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Ausgewählte Publikationen

Liu H-K Human adult hippocampal neurogenesis is back, again? Cell Research (2022) 0:1–2; https://doi.org/10.1038/s41422-022-00698-8

 

• Reddy, N. C., Majidi, S. P., Kong, L., Nemera, M., Ferguson, C. J., Moore, M., ... & Gabel, H. W. (2021).  CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nature communications, 12(1), 1-17.

 

• Bojcevski, J., Wang, C., Liu, H., Abdollahi, A., & Dokic, I. (2021). Assessment of Normal Tissue Radiosensitivity by Evaluating DNA Damage and Repair Kinetics in Human Brain Organoids. International Journal of Molecular Sciences, 22(24), 13195.

 

• Costa, B., Fletcher, M. N., Boskovic, P., Ivanova, E. L., Eisemann, T., Lohr, S., ... & Peterziel, H. (2021). A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors. Cancers, 13(2), 230.

 

• Pajtler, K. W., Wei, Y., Okonechnikov, K., Silva, P. B., Vouri, M., Zhang, L., ... & Kawauchi, D. (2019). YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis. Nature communications, 10(1), 1-16.

 

• Venkataramani, V., Tanev, D. I., Strahle, C., Studier-Fischer, A., Fankhauser, L., Kessler, T., ... & Kuner, T. (2019). Glutamatergic synaptic input to glioma cells drives brain tumour progression. Nature, 573(7775), 532-538.

 

• Duman, C., Yaqubi, K., Hoffmann, A., Acikgöz, A.A., Korshunov, A., Bendszus, M., Herold-Mende, C., Liu, H.-K., and Alfonso, J. (2019). Acyl-CoA-Binding Protein Drives Glioblastoma Tumorigenesis by Sustaining Fatty Acid Oxidation. Cell Metabolism.

 

• Rusu,P., Shao, C., Neuerburg, A., Acikgöz, A.A., Wu, Y., Zou, P., Phapale, P., Shankar, TS., Döring, K., Dettling, S., Körkel-Qu, H., Bekki, G., Costa, B., Guo, T., Friesen, O., Schlotter, M., Heikenwalder, M., Tschaharganeh, DF., Bukan, B., Kramer, G., Angel, P., Herold-Mende, C., Radlwimmer, B., Liu, H-K. (2019) GPD1 specifically marks dormant glioma stem cells with a distinct metabolic profile. Cell Stem Cell
View PDF here

 

• Buchauer, L., Khan, M. A., Zhuo, Y., Shao, C., Zou, P., Feng, W., ... & Liu, H. K. (2019). Exponential Growth of Glioblastoma In Vivo Driven by Rapidly Dividing and Outwardly Migrating Cancer Stem Cells. BioRxiv, 723601.

 

• Costa, B., Eisemann, T., Strelau, J., Spaan, I., Korshunov, A., Liu, H.-K., Bugert, P., Angel, P., and Peterziel, H. (2019). Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells. Blood advances 3, 1092-1102.

 

• Lupo, G., Nisi, P.S., Esteve, P., Paul, Y.L., Novo, C.L., Sidders, B., Khan, M.A., Biagioni, S., Liu, H.K., and Bovolenta, P. (2018). Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline. Aging Cell 17, e12745.

 

• Feng, W., Herbst, L., Lichter, P., Pfister, S.M., Liu, H.-K., and Kawauchi, D. (2018). CRISPR-mediated Loss of Function Analysis in Cerebellar Granule Cells Using In Utero Electroporation-based Gene Transfer. JoVE (Journal of Visualized Experiments), e57311.

 

• Feng, W., Liu, H. K., & Kawauchi, D. (2018). CRISPR-engineered genome editing for the next generation neurological disease modeling. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 81, 459-467.

 

• Liu, H. K. (2017). Artemisinin, GABA signaling and cell reprogramming: when an old drug meets modern medicine. Sci Bull, 62(6), 386-387.

 

• Yong-Sheng Cheng , Yue Zhuo , Katharina Hartmann , Peng Zou , Gözde Bekki , Heike Alter, Hai-Kun Liu. (2017) Autonomous combinatorial color barcoding for multiplexing single molecule RNA visualization. bioRxiv 127373;
Our first preprint open access manuscript introduces a new color coded multiplexing single molecular RNA FISH technic: Hulu FISH)
View PDF here

 

• Grund, T., Goyon, S., Li, Y., Eliava, M., Liu, H., Charlet, A., ... & Neumann, I. D. (2017). Neuropeptide S activates paraventricular oxytocin neurons to induce anxiolysis. Journal of Neuroscience, 37(50), 12214-12225.

 

• Feng, W., Shao, C., & Liu, H. K. (2017). Versatile roles of the chromatin remodeler CHD7 during brain development and disease. Frontiers in Molecular Neuroscience, 10, 309.

 

• Qu, H., Deng, H., Serger, E., Sieber, L., Lieberman, JA., Jimeno-Gonzalez, S., Lambo, S., Hanna, B., Harim, Y., Jansen, M., Neuerburg, A., Friesen, O., Zuckermann, M., Rajendran,V., Gronych, J., Ayrault, O., Korshunov, A., Jones, D., Kool, M., Northcott, P., Lichter, P., Cortes-Ledesma, F., Pfister, SM., Liu H-K. (2017) The chromatin remodeler Chd7 is indispensable for mamalian brain development through activation of a neuronal differentiation programme. Nature Communications.14758 (2017)
View PDF here

 

• Feng, W., Liu, H-K. (2017) Revealing the hidden powers that fuel adult neurogenesis. Cell Stem Cell. 20 (2), 154-156

 

• Wang Q, Satomi K, Oh JE, Hutter B, Brors B, Diessl N, Liu H-K, Wolf S, Wiestler O, Kleihues P, Koelsch B, Kindler-Rohrborn A, Ohgaki H (2016) Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea. American Journal of Pathology 186 (10), 2569-2576

 

• Pajtler, K. W., Brabetz, S., Mauermann, M., Mack, N., Sieber, L., Jones, D. T., ... & Kawauchi, D. (2016). EPN-30YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE. Neuro-Oncology, 18(Suppl 3), iii37.

 

• Osswald, M., Jung, E., Sahm, F., Solecki, G., Venkataramani, V., Blaes, J., Weil, S., Horstmann, H., Wiestler, B., Syed, M., Huang, L., Ratliff, M., Karimian Jazi, K., Kurz, F. T., Schmenger, T., Lemke, D., Gommel, M., Pauli, M., Liao, Y., Haring, P., Pusch, S., Herl, V., Steinhauser, C., Krunic, D., Jarahian, M., Miletic, H., Berghoff, A. S., Griesbeck, O., Kalamakis, G., Garaschuk, O., Preusser, M., Weiss, S., Liu, H-K., Heiland, S., Platten, M., Huber, P. E., Kuner, T., von Deimling, A., Wick, W. and Winkler, F. (2015) Brain tumour cells interconnect to a functional and resistant network. Nature, 528, 93–98
View PDF here

 

• Zhu, Z., Kahn, A., Weiler, M., Blaes. J, Jestaedt L., Geibert M., Zou P., Gronych J., Bernhardt, O., Korshunov, A., Bugner, V., Lichter, P., Radlwimmer, B., Heiland S., Bendszus, M., Wick, W., Liu, H-K*. (2014) Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival. Cell Stem Cell,15, 185-198
(* corresponding author. Highlighted in Nature Reviews Cancer: Cancer stem cell knockout! Previewed in Cell Stem Cell: The tailless root of glioma: cancer stem cells. Cell Stem Cell: Best of 2014, Total 8 Articles were selected)
View PDF here

 

• Wang Y, Liu H-K, Schütz G. (2013). Role of the nuclear receptor tailless in adult neural stem cells. Mechanisms of development, 130(6-8):388-90

 

• Feng, W., & Liu, H. K. (2013). Epigenetic regulation of neuronal fate determination: The role of CHD7. Cell Cycle, 12(24), 3707-3708.

 

• Feng, W., Kahn, A., Bellvis P., Zhu, Z., Bernhardt, O., Herold-Mende, C., Liu, H-K*. (2013). The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors. Cell Stem Cell, 13, 62–72
(*corresponding author, Highlighted with a preview in Cell Stem Cell entitled CHD7 in charge of neurogenesis.)
View PDF here

 

• Peterziel H, Müller J, Danner A, Barbus S, Liu H-K, Radlwimmer B, Pietsch T, Lichter P, Schütz G, Hess J, Angel P. (2012). Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation. Neuro Oncol. 14,426-39
View PDF here

 

• Liu H-K., Wang, Y., Belz, T., Bock, D., Takacs, A., Radlwimmer, B., Barbus, S., Reifenberger, G., Lichter, P., Schütz, G. (2010). The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Genes Dev 24:683-695
(Highlighted, Nature 08. April. 2010, Top of most read papers in Genes Dev, Highlighted by Faculty 1000 biology, F1000 Score 6.0 must read paper)
View PDF here

 

• Liu H-K., Belz T., Bock D., Takacs A., Wu H., Lichter P., Chai M-Q., Schütz G. (2008) The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone. Genes Dev 22:2473-2478 (Highlighted by Faculty 1000 biology, F1000 Score 6.0 must read paper)
View PDF here

 

• Belz, T., Liu, H-K., Bock, D., Takacs, A., Vogt, M., Wintermantel, T., Brandwein, C., Gass, P., Greiner, E., and Schütz, G. (2007). Inactivation of the gene for the nuclear receptor tailless in the brain preserving its function in the eye. Eur J Neurosci 26, 2222-2227.
View PDF here

 

 

 

 

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