Phase X 01.07.2009 - 30.06.2012

Ca.-No 135

Regulation and function of viral and cellular microRNAs controlling the immune response

Israeli Partner: O. Mandelboim, Hebrew University
German Partner: S. Diederichs, DKFZ

Ca.-No 136

Monochlonal antibodies targeting CD24 in the treatment of pancreatic cancer

Israeli Partner: N. Arber, Tel-Aviv Sourasky Med. Center
German Partner: P. Altevogt, DKFZ

Publications

2013 - RNA Biol, 10 (10)

Argonaute-3 activates the let-7a passenger strand microRNA

2012 - Cancer Res, 72 (2): p. 460-71
2012 - Neoplasia, 14 (3): p. 238-48

Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells

2013 - J Invest Dermatol, 133 (3): p. 768-75
2013 - Nucleic Acids Res, 41 (10): p. 5503-12
2011 - Cell Host Microbe, 9 (2): p. 93-102
2010 - Nat Immunol, 11 (9): p. 806-13
2014 - Nat Commun, 5: p. 4186

Ca.-No 137

Regulation of p53 family tumor suppressors under DNA damage stress

Israeli Partner: Y. Shaul, The Weizmann Institute of Science
German Partner: T. Hofmann, DKFZ

Publications

2011 - Gastroenterology, 140 (3): p. 935-46
2010 - Expert Opin Investig Drugs, 19: p. S67-77
2011 - J Biol Chem, 286 (47): p. 40548-55
2014 - Immunol Lett, 161 (1): p. 140-8
2015 - J Biol Chem, 290 (27): p. 16478-88

Ca.-No 138

The complex interactions of semaphorins and the delta-notch pathway in tumor angiogenesis

Israeli Partner: G. Neufeld, Technion
German Partner: A. Fischer, DKFZ

Publications

2013 - Cell Cycle, 13 (1)

Src kinase modulates the apoptotic p53 pathway by altering HIPK2 localization

2013 - Cell Death Differ, 20 (10): p. 1330-40
2015 - J Biol Chem, 290 (27): p. 16478-88

Ca.-No 139

Defining control and function of alternative splicing during tumorigenesis

Israeli Partner: G. Ast, Tel Aviv University
German Partner: A. Hotz-Wagenblatt, DKFZ

Publications

2013 - J Cell Sci, 126: p. 3862-72
2015 - Cancer Res, 75 (11): p. 2177-86
2015 - EMBO Mol Med, 7 (10): p. 1267-84

Publications

2010 - Nat Struct Mol Biol, 17 (9): p. 1114-23
2009 - PLoS Comput Biol, 5 (3): p. e1000300
2013 - Bioinformatics, 29 (9): p. 1141-8
2007 - Genome Biol, 8 (6): p. R127
2007 - BMC Genet, 8: p. 78
2008 - Genome Res, 18 (2): p. 214-20
2013 - PLoS One, 8 (1): p. e53506
2007 - BMC Mol Biol, 8: p. 109
2010 - Nucleic Acids Res, 38 (5): p. 1515-30
2009 - PLoS Genet, 5 (11): p. e1000717
2010 - PLoS One, 5 (6): p. e10907
2012 - Genome Res, 22 (1): p. 35-50
2009 - Nat Struct Mol Biol, 16 (9): p. 990-5
2010 - Nucleic Acids Res, 38 (10): p. 3318-27
2012 - Cell Rep, 1 (5): p. 543-56
2011 - PLoS One, 6 (1): p. e16685
2009 - Nucleic Acids Res, 37: p. W189-92
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