Research
- Research Topics
- Cell Biology and Tumor Biology
- Stem Cells and Cancer
- Inflammatory Stress in Stem Cells
- Experimental Hematology
- Molecular Embryology
- Signal Transduction and Growth Control
- Epigenetics
- Redox Regulation
- Vascular Oncology and Metastasis
- Clinical Neurobiology
- Molecular Neurogenetics
- Molecular Neurobiology
- Mechanisms Regulating Gene Expression
- Molecular Biology of Centrosomes and Cilia
- Dermato-Oncology
- Pediatric Leukemia
- Tumour Metabolism and Microenvironment
- Personalized Medical Oncology
- Molecular Hematology - Oncology
- Cancer Progression and Metastasis
- Translational Surgical Oncology
- Neuronal Signaling and Morphogenesis
- Cell Signaling and Metabolism
- Cell Fate Engineering and Disease Modeling
- Cancer Drug Development
- Cell Morphogenesis and Signal Transduction
- Functional and Structural Genomics
- Molecular Genome Analysis
- Molecular Genetics
- Pediatric Neurooncology
- Cancer Genome Research
- Chromatin Networks
- Functional Genome Analysis
- Theoretical Systems Biology
- Neuroblastoma Genomics
- Signaling and Functional Genomics
- Signal Transduction in Cancer and Metabolism
- RNA-Protein Complexes and Cell Proliferation
- Systems Biology of Signal Transduction
- Areas of Interest
- Advancement of clinical proteomics for systems medicine
- Bridging from the single cell to the cell population – Epo-induced cellular responses and erythroleukemia
- Deciphering tumor microenvironment interactions determining lung cancer development
- Mechanisms controlling the compensation of liver injury and towards model-based biomarkers for early detection of liver cancer
- Application of dynamic pathway modelling for personalized medicine
- Group Members
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- Areas of Interest
- Molecular thoracic Oncology
- Proteomics of Stem Cells and Cancer
- Computational Genomics and System Genetics
- Applied Functional Genomics
- Applied Bioinformatics
- Translational Medical Oncology
- Metabolic crosstalk in cancer
- Pediatric Glioma Research
- Cancer Epigenomics
- Translational Pediatric Sarcoma Research
- Artificial Intelligence in Oncology
- Mechanisms of Genomic Variation and Data Science
- Neuropathology
- Pediatric Oncology
- Neurooncology
- Somatic Evolution and Early Detection
- Translational Control and Metabolism
- Soft-Tissue Sarcoma
- Precision Sarcoma Research
- Brain Mosaicism and Tumorigenesis
- Mechanisms of Genome Control
- Translational Gastrointestinal Oncology and Preclinical Models
- Translational Lymphoma Research
- Mechanisms of Leukemogenesis
- Genome Instability in Tumors
- Developmental Origins of Pediatric Cancer
- Brain Tumor Translational Targets
- Translational Functional Cancer Genomics
- Regulatory Genomics and Cancer Evolution
- SPRINT
- Cancer Risk Factors and Prevention
- Cancer Epidemiology
- Biostatistics
- Clinical Epidemiology and Aging Research
- Health Economics
- Physical Activity, Prevention and Cancer
- Primary Cancer Prevention
- Personalized Early Detection of Prostate Cancer
- Digital prevention, diagnostics and therapy guidance
- Policy and Implementation Research for Cancer Prevention
- Tumorigenesis and molecular cancer prevention
- Genomic Epidemiology
- Cancer Survivorship
- Immunology, Infection and Cancer
- Structural Biology of Infection and Immunity
- Cellular Immunology
- B Cell Immunology
- Immune Diversity
- Immunoproteomics
- Personalized Immunotherapy
- mRNA Cancer Immunotherapies
- Tumor Immunology and Tumor Immunotherapy
- Infections and Cancer Epidemiology
- Pathogenesis of Virus-Associated Tumors
- Immunotherapy and Immunoprevention
- Virus-associated Carcinogenesis
- Chronic Inflammation and Cancer
- Microbiome and Cancer
- Molecular Oncology of Gastrointestinal Tumors
- Applied Tumor Immunity
- Neuroimmunology and Brain Tumor Immunology
- Applied Tumor Biology
- Virotherapy
- Adaptive Immunity and Lymphoma
- Dermal Oncoimmunology
- Immune Regulation in Cancer
- Systems Immunology and Single Cell Biology
- Pediatric Immuno-Oncology
- Epithelium Microbiome lnteractions
- Experimental Hepatology, Inflammation and Cancer
- GMP & T Cell Therapy
- Tumorvirus-specific Vaccination Strategies
- Mammalian Cell Cycle Control Mechanisms
- Molecular Therapy of Virus-Associated Cancers
- DNA Vectors
- Episomal-Persistent DNA in Cancer- and Chronic Diseases
- Immune Monitoring
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- Computational Radiology Research Group
- Contrast Agents In Radiology Research Group
- Neuro-Oncologic Imaging Research Group
- Radiological Early Response Assessment Of Modern Cancer Therapies
- Imaging In Monoclonal Plasma Cell Disorders
- 7 Tesla MRI - Novel Imaging Biomarkers
- Functional Imaging
- Visualization And Forensic Imaging
- PET/MRI
- Dual- and Multienergy CT
- Radiomics Research Group
- Prostate Research Group
- Bone marrow
- Musculoskeletal Imaging
- Microstructural Imaging Research Group
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- Medical Physics in Radiology
- X-Ray Imaging and Computed Tomography
- Federated Information Systems
- Translational Molecular Imaging
- Medical Physics in Radiation Oncology
- Biomedical Physics in Radiation Oncology
- Intelligent Medical Systems
- Medical Image Computing
- Radiooncology - Radiobiology
- Smart Technologies for Tumor Therapy
- Team
- Research
- Microrobots and Miniaturize Devices for Minimally-invasive Surgery
- Magnetic localization and sensing for biomedical devices
- Nanorobots for Targeted Delivery in Deep Biological Tissues
- 3D Additive Manufacturing of Soft Materials as In Vitro Tumor Models
- Surgical Simulation on Cyber-physical Organ Models
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- Radiation Oncology
- Molecular Radiooncology
- Nuclear Medicine
- Translational Radiation Oncology
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- Interactive Machine Learning
- Intelligent Systems and Robotics in Urology
- Multiparametric methods for early detection of prostate cancer
- Translational Molecular Imaging in Oncologic Therapy Monitoring
- Radiology
- Cell Biology and Tumor Biology
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- Microbiological Diagnostics
- Next Generation Sequencing
- Omics IT and Data Management
- Proteomics
- Radiopharmaceuticals and Preclinical Trials
- Single-cell Open Lab
- Small Animal Imaging
- Transgenic Service
- Tumor Models
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- Baden-Württemberg Cancer Registry
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- Heidelberg - Israel, Science and Culture
- Symposium 40 Years of German-Israeli Cooperation
- 35th Anniversary Symposium
- 34th Meeting of the DKFZ-MOST Program
- 40th Anniversary Publication
- 30th Anniversary Publication
- 20th Anniversary Publication
- Flyer - The Cancer Cooperation Program
- List Publications 1976-2004
- Highlight-Projects
- Cooperational Research Program with Israel: DKFZ - MOST in Cancer Research
- Cooperations with industrial companies
- DKFZ PostDoc Network
- Cross Program Topic RNA@DKFZ
- Cross Program Topic Epigenetics@dkfz
- Cross Program Topic Single Cell Sequencing
- WHO Collaborating Centers
- DKFZ Site Dresden
- Health + Life Science Alliance Heidelberg Mannheim
Ignacio Mastandrea
Ignacio Mastandrea
Position:
Postdoctoral Researcher
Scientific CV
Since January 2023
Postdoctoral Researcher, Division of Microbiome and Cancer, DKFZ, Heidelberg, Germany
2017-2022
Ph.D. Candidate. School of Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel
2015 – 2017
MSc Cellular and Molecular Biology, Basic Sciences Development Program (PEDECIBA) Montevideo, Uruguay
2011-2015
BSc Biochemistry, Universidad de la República, Montevideo, Uruguay
Selected Publications
Mastandrea I, Sher D, Magod P, Friedmann-Morvinski D. (2022) Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment. STAR Protocols 3, 101106.
Magod P, Mastandrea I, Rousso-Noori L, Agemi L, Shapira G, Shomron N, Friedmann- Morvinski D. (2021) Exploring the Longitudinal Glioma Microenvironment Landscape Uncovers Reprogrammed Pro-Tumorigenic Neutrophils in the Bone Marrow. Cell Reports 36(5):109480.
Rousso-Noori L#, Mastandrea I#, Talmor S, Waks T, Globerson Levin A, Haugas M, Teesalu T, Alvarez-Vallina L, Eshhar Z, Friedmann-Morvinski D. (2021) P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas. Nat Commun. 12(1):3615. (#contributed equally).
Säälik P, Lingasamy P, Toome K, Mastandrea I, Rousso- Noori L, Tobi A, Simón-Gracia L, Hunt H, Paiste P, Kotamraju VR, Bergers G, Asser T, Rätsep T, Ruoslahti E, Bjerkvig R, Friedmann- Morvinski D, Teesalu T. (2019) Peptide-guided nanoparticles for glioblastoma targeting. J Control Release 308:109-118.