Cookie Settings

We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .


These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name Webedition CMS
Purpose This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name econda
Purpose Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name econda
Purpose Statistics
External media

Content from external media platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name YouTube
Purpose Show YouTube content
Name Twitter
Purpose activate Twitter Feeds

Synchromodal emission imaging


To enable what we call synchromodal optical imaging we invented the first plenoptic camera for diagnostic research that not only creates three-dimensional (illumination and fluence) projections of the imaged subject, but can also be integrated and used with PET and MRI (reference). The world's first simultaneously acquired [18F]FDG PET - pVEGF Luc BLI plenoptic image is shown in the left figure (top: experimental plenoptic system integrated into a Siemens Inveon PET for simultaneous data acquisition, bottom: fused PET and OI data (reference)).

A complete instrumentation and mathematical framework for preclinical plenoptic imaging (POI) is developed in which optical data is acquired by means of a microlens array (MLA) based light detector (MLA-D). The MLA-D has been developed to enable unique POI, especially in synchromodal operation with secondary imaging modalities such as PET or MRI. An MLA-D consists of a (large-area) photon sensor array, a matched MLA for field-of-view definition, and a septum mask of specific geometry made of anodized aluminum that is positioned between the sensor and the MLA to suppresses light cross-talk and to shield the sensor's radiofrequency interference signal (essential when used inside an MRI system). The software framework, while freely parameterizable for any MLA-D, is tailored towards a POI prototype system for preclinical synchromodal imaging application comprising a multitude of cylindrically assembled, gantry-mounted, simultaneously operating MLA-D's. When used in synchromodal operation, reconstructed tomographic volume data can be used for co-modal image fusion and also as a prior for estimating the imaged object's 3D surface by means of gradient vector flow. Superimposed planar or surface-aligned inverse mapping can be performed to estimate and to fuse the emission light map with the boundary of the imaged object. Triangulation and subsequent optical reconstruction can be performed to estimate the internal three-dimensional emission light distribution. The framework is susceptible to a number of variables controlling convergence and computational speed.

(← back to research group home web page)

to top
powered by webEdition CMS