This project seeks to contribute to the advancement of PET instrumentation and the development of novel multimodal techniques. From preclinical systems to whole-body clinical systems a focus is drawn on investigating monolithic-detector design primarily through the use of computational simulations and with the support of basic experimental tests. The simulation approach includes the full simulation of scintillation photons within the crystals and therefore constitutes a powerful tool being used to optimise the co-dependent scanner geometrical design and the applied gamma-ray point-of-interaction determination algorithm. A prototype for a multimodal preclinical scanner integrating PET imaging with optical tomography is currently being developed using said tools.

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