CLARITY

CLARITY - ­CineMR-guided ML-driven breaAthing models for adaptive RadIoTherapY

Dose escalation in breathing anatomies of ultra-central lung cancer lesions is based on cutting-edge LINAC-integrated imaging technology using 2D cineMR time series combined with high-end adaptation strategies. Yet, the 4D motion trajectories still cannot be visualized and processed online with available technologies. 

In this Helmholtz Imaging-funded project our team investigates biomechanical and ML-based 4D motion modelling approaches for their ability and reliability to predict critical deformation events of organ at risks from 2D cineMR. 

Team: Richard Häcker (DKFZ), Kristina Giske (DKFZ), Oliver Jäkel (DKFZ), Daniel Lang (HMGU), Julia Schnabel (HMGU, TUM)

Collaborators: Sebastian Klüter (UKHD), Sebastian Regnery (UKHD), Juliane Hörner-Rieber (UKHD)

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