Interactions between cancer associated fibroblasts (CAFs) and myeloid-derived inflammatory cells in the dynamic phenotype of the microenvironment during tumor progression; basic mechanisms and preclinical applications of novel intervention strategies

Number of publications: 7
Israeli Partner: R. Apte, Ben-Gurion University
German Partner: M. Mueller, DKFZ


Bersudsky, M., Luski, L., Fishman, D., White, R. M., Ziv-Sokolovskaya, N., Dotan, S., Rider, P., Kaplanov, I., Aychek, T., Dinarello, C. A., Apte, R. N., Voronov, E.

Non-redundant properties of IL-1alpha and IL-1beta during acute colon inflammation in mice, Gut, 2013

Carmi, Y., Dotan, S., Rider, P., Kaplanov, I., White, M. R., Baron, R., Abutbul, S., Huszar, M., Dinarello, C. A., Apte, R. N., Voronov, E.

The role of IL-1beta in the early tumor cell-induced angiogenic response 190 (7), J Immunol, 3500-9, 2013

Carmi, Y., Rinott, G., Dotan, S., Elkabets, M., Rider, P., Voronov, E., Apte, R. N.

Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis 186 (6), J Immunol, 3462-71, 2011

Meides, A., Gutschalk, C. M., Devel, L., Beau, F., Czarny, B., Hensler, S., Neugebauer, J., Dive, V., Angel, P., Mueller, M. M.

Effects of selective MMP-13 inhibition in squamous cell carcinoma depend on estrogen 135 (12), Int J Cancer, 2749-59, 2014

Rider, P., Carmi, Y., Voronov, E., Apte, R. N.

Interleukin-1alpha 25 (6), Semin Immunol, 430-8, 2013

Rider, P., Kaplanov, I., Romzova, M., Bernardis, L., Braiman, A., Voronov, E., Apte, R. N.

The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells 3, Front Immunol, 290, 2012

Voronov, E., Dotan, S., Krelin, Y., Song, X., Elkabets, M., Carmi, Y., Rider, P., Idan, Cohen, Romzova, M., Kaplanov, I., Apte, R. N.

Unique Versus Redundant Functions of IL-1alpha and IL-1beta in the Tumor Microenvironment 4, Front Immunol, 177, 2013

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