Characterization and regulation of NCR and NKG2D ligands in cancer

Number of publications: 5
Israeli Partner: A. Porgador, Ben-Gurion Univ.
German Partner: A. Cerwenka, DKFZ


Brusilovsky, M., Cordoba, M., Rosental, B., Hershkovitz, O., Andrake, M. D., Pecherskaya, A., Einarson, M. B., Zhou, Y., Braiman, A., Campbell, K. S., Porgador, A.

Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses 191 (10), J Immunol, 5256-67, 2013

Fiegler, N., Textor, S., Arnold, A., Rolle, A., Oehme, I., Breuhahn, K., Moldenhauer, G., Witzens-Harig, M., Cerwenka, A.

Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells 122 (5), Blood, 684-93, 2013

Ni, J., Miller, M., Stojanovic, A., Garbi, N., Cerwenka, A.

Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors 209 (13), J Exp Med, 2351-65, 2012

Rosental, B., Brusilovsky, M., Hadad, U., Oz, D., Appel, M. Y., Afergan, F., Yossef, R., Rosenberg, L. A., Aharoni, A., Cerwenka, A., Campbell, K. S., Braiman, A., Porgador, A.

Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44 187 (11), J Immunol, 5693-702, 2011

Textor, S., Fiegler, N., Arnold, A., Porgador, A., Hofmann, T. G., Cerwenka, A.

Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2 71 (18), Cancer Res, 5998-6009, 2011

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