Intracellular signalling pathways controlling cell fate decisions of lymphocytes during differentiation and tumorigenesis

Number of publications: 4
Israeli Partner: D. Melamed, Technion
German Partner: R. Arnold, P. Krammer, DKFZ


Benhamou, D., Labi, V., Novak, R., Dai, I., Shafir-Alon, S., Weiss, A., Gaujoux, R., Arnold, R., Shen-Orr, S. S., Rajewsky, K., Melamed, D.

A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency 16 (2), Cell Rep, 419-431, 2016

Brenner, D., Brechmann, M., Rohling, S., Tapernoux, M., Mock, T., Winter, D., Lehmann, W. D., Kiefer, F., Thome, M., Krammer, P. H., Arnold, R.

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells 106 (34), Proc Natl Acad Sci U S A, 14508-13, 2009

Brenner, D., Golks, A., Kiefer, F., Krammer, P. H., Arnold, R.

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death 24 (24), Embo j, 4279-90, 2005

Novak, R., Jacob, E., Haimovich, J., Avni, O., Melamed, D.

The MAPK/ERK and PI3K pathways additively coordinate the transcription of recombination-activating genes in B lineage cells 185 (6), J Immunol, 3239-47, 2010

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