Inflammation-dependent immunosuppressive tumor microenvironment: Its neutralization for successful tumor immunotherapy

Number of publications: 10
Israeli Partner: M. Baniyasch, Hebrew University
German Partner: V. Umansky (div. of D. Schadendorf), DKFZ

Publications

Publication
Publication
Baniyash, M., Sade-Feldman, M., Kanterman, J.

Chronic inflammation and cancer: suppressing the suppressors, Cancer Immunol Immunother, 2013

Fujimura, T., Ring, S., Umansky, V., Mahnke, K., Enk, A. H.

Regulatory T cells stimulate B7-H1 expression in myeloid-derived suppressor cells in ret melanomas 132 (4), J Invest Dermatol, 1239-46, 2012

Kanterman, J., Sade-Feldman, M., Baniyash, M.

New insights into chronic inflammation-induced immunosuppression 22 (4), Semin Cancer Biol, 307-18, 2012

Meyer, C., Sevko, A., Ramacher, M., Bazhin, A. V., Falk, C. S., Osen, W., Borrello, I., Kato, M., Schadendorf, D., Baniyash, M., Umansky, V.

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model 108 (41), Proc Natl Acad Sci U S A, 17111-6, 2011

Michels, T., Shurin, G. V., Naiditch, H., Sevko, A., Umansky, V., Shurin, M. R.

Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner 9 (3), J Immunotoxicol, 292-300, 2012

Sade-Feldman, M., Kanterman, J., Ish-Shalom, E., Elnekave, M., Horwitz, E., Baniyash, M.

Tumor necrosis factor-alpha blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation 38 (3), Immunity, 541-54, 2013

Sevko, A., Sade-Feldman, M., Kanterman, J., Michels, T., Falk, C. S., Umansky, L., Ramacher, M., Kato, M., Schadendorf, D., Baniyash, M., Umansky, V.

Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma 133 (6), J Invest Dermatol, 1610-9, 2013

Umansky, V., Sevko, A.

Melanoma-induced immunosuppression and its neutralization 22 (4), Semin Cancer Biol, 319-26, 2012

Umansky, V., Sevko, A.

Tumor microenvironment and myeloid-derived suppressor cells 6 (2), Cancer Microenviron, 169-77, 2013

Umansky, V., Sevko, A.

Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation 61 (2), Cancer Immunol Immunother, 275-82, 2012

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