Macromolecular polymers as a novel platform for the tumor directed delivery of drugs targeting molecular processes of apoptosis and radiation

Number of publications: 10
Israeli Partner: S. Lavi, Tel Aviv University
German Partner: P. Peschke (div. P. Huber), DKFZ


Kiessling, F., Heilmann, M., Lammers, T., Ulbrich, K., Subr, V., Peschke, P., Waengler, B., Mier, W., Schrenk, H. H., Bock, M., Schad, L., Semmler, W.

Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography 17 (1), Bioconjug Chem, 42-51, 2006

Lammers, T., Kuhnlein, R., Kissel, M., Subr, V., Etrych, T., Pola, R., Pechar, M., Ulbrich, K., Storm, G., Huber, P., Peschke, P.

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers 110 (1), J Control Release, 103-18, 2005

Lammers, T., Lavi, S.

Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling 42 (6), Crit Rev Biochem Mol Biol, 437-61, 2007

Lammers, T., Peschke, P., Ehemann, V., Debus, J., Slobodin, B., Lavi, S., Huber, P.

Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity 6, Mol Cancer, 65, 2007

Lammers, T., Peschke, P., Kuhnlein, R., Subr, V., Ulbrich, K., Huber, P., Hennink, W., Storm, G.

Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems 8 (10), Neoplasia, 788-95, 2006

Lammers, T., Subr, V., Peschke, P., Kuhnlein, R., Hennink, W. E., Ulbrich, K., Kiessling, F., Heilmann, M., Debus, J., Huber, P. E., Storm, G.

Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy 99 (6), Br J Cancer, 900-10, 2008

Lammers, T., Subr, V., Ulbrich, K., Peschke, P., Huber, P. E., Hennink, W. E., Storm, G.

Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers 30 (20), Biomaterials, 3466-75, 2009

Lammers, T., Subr, V., Ulbrich, K., Peschke, P., Huber, P. E., Hennink, W. E., Storm, G., Kiessling, F.

HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations 5 (10), Nanomedicine (Lond), 1501-23, 2010

Lammers, T., Ulbrich, K.

HPMA copolymers: 30 years of advances 62 (2), Adv Drug Deliv Rev, 119-21, 2010

Shohat, M., Ben-Meir, D., Lavi, S.

Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells 7 (2), PLoS One, e32438, 2012

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