Epigenomics of hormone-driven cancers

Major Research Direction
In the Epigenomics of hormone-driven cancers group, current projects focus on
- The role of 5-hydroxymethylation in human adipogenesis
- Profiling DNA hydroxy-/methylation and chromatin accessibility in human intervention studies
- Epigenetic mechanisms in cancer and metastasis development, with a focus on breast and prostate cancer
- Developing biomarkers for endogenous endocrine resistance in breast cancer
- Characterizing the enhancer methylome in prostate cancer
- The pan-prostate cancer methylome landscape
Members
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Dr. Clarissa Gerhäuser
Group Leader Prostate Cancer Epigenomics
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Nan Zhang
PhD Student
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Maxime de Vrieze