PERSPECTIVEs of patients on exercise interventions after the diagnosis of metastasized breast cancer

The PERSPECTIVE study at a glance

  • Study objective: Examine patients' perspective on exercise interventions
  • Target group: Patients with advanced breast cancer (i.e. metastatic breast cancer)
  • Study design: Cross-sectional (one-time survey)

The PERSPECTIVE study is conducted in 5 EU countries (Germany, the Netherlands, Poland, Sweden, Spain) within the framework of the EU Horizon 2020 funded PREFERABLE project. The PREFERABLE project is coordinated by UMC Utrecht in the Netherlands.

Further information about PREFERABLE can be found here:

Overall project coordination:

Prof. Dr. Anne May (UMC Utrecht), Dr. Martijn Stuiver (NKI Amsterdam)

Study center Heidelberg:

Prof. Dr. Karen Steindorf, Prof. Dr. Andreas Schneeweiss


Numerous studies suggest that physical activity can lead to a reduction in treatment-related side effects such as fatigue, a reduction in depression symptoms and an increase in self-esteem among breast cancer patients receiving adjuvant therapy. The evidence for breast cancer patients with advanced disease is still scarce. Physical training appears as a promising intervention to reduce fatigue symptoms and improve quality of life also among patients with metastatic disease. In order to successfully implement such interventions for patients with metastatic breast cancer, it is crucial to gain a better understanding of patients’ goals, expectations and barriers regarding exercise interventions.

The aim of the PERSPECTIVE study is to comprehensively examine the perspective of patients with metastatic breast cancer on exercise interventions.

In the survey, patients are asked about their attitudes towards exercise interventions, potential barriers, facilitators, personal goals, expectations and preferences. In addition, the relation of these factors to personal and medical characteristics of the patients as well as regional and cultural factors is investigated. The insights gained from the PERSPECTIVE study will then be used to successfully integrate exercise interventions into the daily lives of patients with metastatic disease.

Current status

Recruitment started in May 2020.


Johanna Depenbusch
phone: +49 6221 42 2201


PREFERABLE has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 825677.

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