Publikationen

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Xu, K. ; Kessler, A. ; Nichetti, F. (First author)DKFZ* ; Hoffmeister-Wittmann, P. ; Scherr, A.-L. ; Nader, L. ; Kelmendi, E. ; Schmitt, N. ; Schwab, M. ; García-Beccaria, M.DKFZ* ; Sobol, B. ; Nieto, O. A. ; Isele, H. ; Gärtner, U. ; Vaquero-Siguero, N.DKFZ* ; Volk, J.DKFZ* ; Korell, F.DKFZ* ; Mock, A.DKFZ* ; Heide, D.DKFZ* ; Ramadori, P.DKFZ* ; Lenoir, B.DKFZ* ; Albrecht, T. ; Hüllein, J.DKFZ* ; Jäger, D.DKFZ* ; Fröhling, S.DKFZ* ; Springfeld, C. ; Jackstadt, R.-F.DKFZ* ; Heikenwälder, M.DKFZ* ; Dill, M.DKFZ* ; Roessler, S. ; Goeppert, B. ; Köhler, B. C.DKFZ*
Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma.
Liver international 44(11), 2950-2963 (2024) [10.1111/liv.16069]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Fey, S. K. (First author)DKFZ* ; Vaquero-Siguero, N. (First author)DKFZ* ; Jackstadt, R.-F. (Last author)DKFZ*
Dark force rising: Reawakening and targeting of fetal-like stem cells in colorectal cancer.
Cell reports 43(6), 114270 (2024) [10.1016/j.celrep.2024.114270]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article/Contribution to a conference proceedings/Contribution to a book Maier, A. (Editor) ; Deserno, T. M. (Editor) ; Handels, H. (Editor) ; Maier-Hein, K. (Editor)DKFZ* ; Palm, C. (Editor) ; Tolxdorff, T. (Editor) ; Eixelberger, T. ; Fang, Q. ; Zohud, B. A. ; Hackner, R. ; Jackstadt, R.DKFZ* ; Stürzl, M. ; Naschberger, E. ; Wittenberg, T.
Automated Lesion Detection in Endoscopic Imagery for Small Animal Models
2024Bildverarbeitung für die Medizin 2024 / Maier, Andreas (Editor) [https://orcid.org/0000-0002-9550-5284] ; Wiesbaden : Springer Fachmedien Wiesbaden, 2024, Chapter 54 ; ISSN: 1431-472X=2628-8958 ; ISBN: 978-3-658-44036-7=978-3-658-44037-4 ; doi:10.1007/978-3-658-44037-4
German Conference on Medical Image Computing, BVM 2024, ErlangenErlangen, Germany, 24 Mar 2024 - 24 Mar 20242024-03-242024-03-24 Informatik aktuell 190 - 195 (2024) [10.1007/978-3-658-44037-4_54]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Malviya, G. ; Lannagan, T. R. M. ; Johnson, E. ; Mackintosh, A. ; Bielik, R. ; Peters, A. ; Soloviev, D. ; Brown, G. ; Jackstadt, R.-F.DKFZ* ; Nixon, C. ; Gilroy, K. ; Campbell, A. ; Sansom, O. J. ; Lewis, D. Y.
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging.
Clinical cancer research 30(8), 1518-1529 (2024) [10.1158/1078-0432.CCR-23-1063]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Hermosilla, V. E. ; Gyenis, L. ; Rabalski, A. J. ; Armijo, M. E. ; Sepúlveda, P. ; Duprat, F. ; Benítez-Riquelme, D. ; Fuentes-Villalobos, F. ; Quiroz, A. ; Hepp, M. I. ; Farkas, C. ; Mastel, M.DKFZ* ; González-Chavarría, I. ; Jackstadt, R.DKFZ* ; Litchfield, D. W. ; Castro, A. F. ; Pincheira, R.
Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells.
Cell death & disease 15(3), 223 (2024) [10.1038/s41419-024-06591-z]2024     Files BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Fetit, R. ; McLaren, A. ; White, M. ; Mills, M. L. ; Falconer, J. ; Cortes-Lavaud, X. ; Gilroy, K. ; Lannagan, T. R. ; Ridgway, R. A. ; Nixon, C. ; Naiker, V. ; Njunge, R. ; Clarke, C. J. ; Whyte, D. ; Kirschner, K. ; Jackstadt, R.-F.DKFZ* ; Norman, J. C. ; Carlin, L. M. ; Campbell, A. D. ; Sansom, O. J. ; Steele, C. W.
Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1?/CXCR2 axis in generation of metastasis specific neutrophils.
Cancer research communications 4(2), 588-606 (2024) [10.1158/2767-9764.CRC-23-0319]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Scherr, A.-L. ; Nader, L. ; Xu, K. ; Elssner, C. ; Ridder, D. A. ; Nichetti, F. ; Mastel, M.DKFZ* ; Fritzsche, S. ; Kelmendi, E. ; Schmitt, N. ; Hoffmeister-Wittmann, P. ; Weiler, S. M. E. ; Korell, F.DKFZ* ; Albrecht, T. ; Schwab, M. ; Isele, H. ; Kessler, A. ; Hüllein, J. ; Seretny, A.DKFZ* ; Ye, L. ; Urbanik, T. ; Welte, S. ; Leblond, A.-L. ; Heilig, C.DKFZ* ; Rahbari, M.DKFZ* ; Ali, A.DKFZ* ; Gallage, S. U.DKFZ* ; Lenoir, B. M. A.DKFZ* ; Wilhelm, N.DKFZ* ; Gärtner, U. ; Ogrodnik, S. J.DKFZ* ; Springfeld, C. ; Tschaharganeh, D. F.DKFZ* ; Fröhling, S.DKFZ* ; Longerich, T. ; Schulze-Bergkamen, H. ; Jäger, D.DKFZ* ; Brandl, L. ; Schirmacher, P. ; Straub, B. K. ; Weber, A. ; De Toni, E. N. ; Goeppert, B. ; Heikenwälder, M.DKFZ* ; Jackstadt, R.-F.DKFZ* ; Roessler, S. ; Breuhahn, K. ; Köhler, B. C.DKFZ*
Etiology-independent activation of the LT?-LT?R-RELB axis drives aggressiveness and predicts poor prognosis in Hepatocellular carcinoma.
Hepatology 80(2), 278-294 (2024) [10.1097/HEP.0000000000000657]2024   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Erratum/Correction) Flanagan, D. J. ; Amirkhah, R. ; Vincent, D. F. ; Gunduz, N. ; Gentaz, P. ; Cammareri, P. ; McCooey, A. J. ; McCorry, A. M. B. ; Fisher, N. C. ; Davis, H. L. ; Ridgway, R. A. ; Lohuis, J. ; Leach, J. D. G. ; Jackstadt, R.DKFZ* ; Gilroy, K. ; Mariella, E. ; Nixon, C. ; Clark, W. ; Hedley, A. ; Markert, E. K. ; Strathdee, D. ; Bartholin, L. ; Redmond, K. L. ; Kerr, E. M. ; Longley, D. B. ; Ginty, F. ; Cho, S. ; Coleman, H. G. ; Loughrey, M. B. ; Bardelli, A. ; Maughan, T. S. ; Campbell, A. D. ; Lawler, M. ; Leedham, S. J. ; Barry, S. T. ; Inman, G. J. ; van Rheenen, J. ; Dunne, P. D. ; Sansom, O. J.
Author Correction: Epithelial TGF? engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Nature Communications 14(1), 522 (2023) [10.1038/s41467-023-36266-w]2023   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Betge, J. (First author)DKFZ* ; Jackstadt, R.-F. (Last author)DKFZ*
From organoids to bedside: advances in modeling, decoding and targeting of colorectal cancer
International journal of cancer 152(7), 1304-1313 (2023) [10.1002/ijc.34297]2023   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Bailey, P. ; Ridgway, R. A. ; Cammareri, P. ; Treanor-Taylor, M. ; Bailey, U.-M. ; Schoenherr, C. ; Bone, M. ; Schreyer, D. ; Purdie, K. ; Thomson, J. ; Rickaby, W. ; Jackstadt, R.DKFZ* ; Campbell, A. D. ; Dimonitsas, E. ; Stratigos, A. J. ; Arron, S. T. ; Wang, J. ; Blyth, K. ; Proby, C. M. ; Harwood, C. A. ; Sansom, O. J. ; Leigh, I. M. ; Inman, G. J.
Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression.
Nature Communications 14(1), 5211 (2023) [10.1038/s41467-023-40822-9]2023     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Wittner, L. ; Wagener, L. ; Wiese, J. J. ; Stolzer, I. ; Krug, S. M. ; Naschberger, E. ; Jackstadt, R.-F.DKFZ* ; Beyaert, R. ; Atreya, R. ; Kühl, A. A. ; Sturm, G. ; Gonzalez-Acera, M. ; Patankar, J. V. ; Becker, C. ; Siegmund, B. ; Trajanoski, Z. ; Winner, B. ; Neurath, M. F. ; Schumann, M. ; Günther, C.
Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing.
International journal of molecular sciences 24(8), 7402 (2023) [10.3390/ijms24087402]2023   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Flanagan, D. J. ; Amirkhah, R. ; Vincent, D. F. ; Gundaz, N. ; Gentaz, P. ; Cammareri, P. ; McCooey, A. J. ; McCorry, A. M. B. ; Fisher, N. C. ; Davis, H. L. ; Ridgway, R. A. ; Lohuis, J. ; Leach, J. D. G. ; Jackstadt, R.DKFZ* ; Gilroy, K. ; Mariella, E. ; Nixon, C. ; Clark, W. ; Hedley, A. ; Markert, E. K. ; Strathdee, D. ; Bartholin, L. ; Redmond, K. L. ; Kerr, E. M. ; Longley, D. B. ; Ginty, F. ; Cho, S. ; Coleman, H. G. ; Loughrey, M. B. ; Bardelli, A. ; Maughan, T. S. ; Campbell, A. D. ; Lawler, M. ; Leedham, S. J. ; Barry, S. T. ; Inman, G. J. ; van Rheenen, J. ; Dunne, P. D. ; Sansom, O. J.
Epithelial TGF? engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Nature Communications 13(1), 7551 (2022) [10.1038/s41467-022-35134-3]2022     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Vaquero-Siguero, N. (First author)DKFZ* ; Schleussner, N.DKFZ* ; Volk, J.DKFZ* ; Mastel, M.DKFZ* ; Meier, J.DKFZ* ; Jackstadt, R.-F. (Last author)DKFZ*
Modeling Colorectal Cancer Progression Reveals Niche-Dependent Clonal Selection
Cancers 14(17), 4260 (2022) [10.3390/cancers14174260]2022   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Weisshaar, N. (First author)DKFZ* ; Wu, J.DKFZ* ; Ming, Y.DKFZ* ; Madi, A. A. M.DKFZ* ; Hotz-Wagenblatt, A.DKFZ* ; Ma, S.DKFZ* ; Mieg, A.DKFZ* ; Hering, M.DKFZ* ; Zettl, F.DKFZ* ; Mohr, K.DKFZ* ; Schlimbach, T.DKFZ* ; Ten Bosch, N.DKFZ* ; Hertel, F.DKFZ* ; Müller, L.DKFZ* ; Byren, H.DKFZ* ; Wang, M.DKFZ* ; Borgers, H.DKFZ* ; Munz, M.DKFZ* ; Schmitt, L.DKFZ* ; van der Hoeven, F.DKFZ* ; Kloz, U.DKFZ* ; Carretero, R.DKFZ* ; Schleußner, N.DKFZ* ; Jackstadt, R.-F.DKFZ* ; Hofmann, I.DKFZ* ; Cui, G. (Last author)DKFZ*
Rgs16 promotes antitumor CD8+ T cell exhaustion.
Science immunology 7(71), eabh1873 (2022) [10.1126/sciimmunol.abh1873]2022   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Corry, S. M. ; McCorry, A. M. ; Lannagan, T. R. ; Leonard, N. A. ; Fisher, N. C. ; Byrne, R. M. ; Tsantoulis, P. ; Cortes-Lavaud, X. ; Amirkhah, R. ; Redmond, K. L. ; McCooey, A. J. ; Malla, S. B. ; Rogan, E. ; Sakhnevych, S. ; Gillespie, M. A. ; White, M. ; Richman, S. D. ; Jackstadt, R.-F.DKFZ* ; Campbell, A. D. ; Maguire, S. ; S:CORT ; consortia, A. (Collaboration Author) ; McDade, S. S. ; Longley, D. B. ; Loughrey, M. B. ; Coleman, H. G. ; Kerr, E. M. ; Tejpar, S. ; Maughan, T. ; Leedham, S. J. ; Small, D. M. ; Ryan, A. E. ; Sansom, O. J. ; Lawler, M. ; Dunne, P. D.
Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.
Gut 71(12), 2502-2517 (2022) [10.1136/gutjnl-2021-326183]2022   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Knight, J. R. P. ; Alexandrou, C. ; Skalka, G. L. ; Vlahov, N. ; Pennel, K. ; Officer, L. ; Teodosio, A. ; Kanellos, G. ; Gay, D. M. ; May-Wilson, S. ; Smith, E. M. ; Najumudeen, A. K. ; Gilroy, K. ; Ridgway, R. A. ; Flanagan, D. J. ; Smith, R. C. L. ; McDonald, L. ; MacKay, C. ; Cheasty, A. ; McArthur, K. ; Stanway, E. ; Leach, J. D. ; Jackstadt, R.-F.Extern* ; Waldron, J. A. ; Campbell, A. D. ; Vlachogiannis, G. ; Valeri, N. ; Haigis, K. M. ; Sonenberg, N. ; Proud, C. G. ; Jones, N. P. ; Swarbrick, M. E. ; McKinnon, H. J. ; Faller, W. J. ; Le Quesne, J. ; Edwards, J. ; Willis, A. E. ; Bushell, M. ; Sansom, O. J.
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
Cancer discovery 11(5), 1228 - 1247 (2021) [10.1158/2159-8290.CD-20-0652]2021     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Nielsen, S. R. ; Strøbech, J. E. ; Horton, E. R. ; Jackstadt, R.-F.Extern* ; Laitala, A. ; Bravo, M. C. ; Maltese, G. ; Jensen, A. R. D. ; Reuten, R. ; Rafaeva, M. ; Karim, S. A. ; Hwang, C.-I. ; Arnes, L. ; Tuveson, D. A. ; Sansom, O. J. ; Morton, J. P. ; Erler, J. T.
Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade.
Nature Communications 12(1), 3414 (2021) [10.1038/s41467-021-23731-7]2021     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Leach, J. D. G. ; Vlahov, N. ; Tsantoulis, P. ; Ridgway, R. A. ; Flanagan, D. J. ; Gilroy, K. ; Sphyris, N. ; Vázquez, E. G. ; Vincent, D. F. ; Faller, W. J. ; Hodder, M. C. ; Raven, A. ; Fey, S. ; Najumudeen, A. K. ; Strathdee, D. ; Nixon, C. ; Hughes, M. ; Clark, W. ; Shaw, R. ; consortium, S. (Collaboration Author) ; van Hooff, S. R. ; Huels, D. J. ; Medema, J. P. ; Barry, S. T. ; Frame, M. C. ; Unciti-Broceta, A. ; Leedham, S. J. ; Inman, G. J. ; Jackstadt, R.-F.Extern* ; Thompson, B. J. ; Campbell, A. D. ; Tejpar, S. ; Sansom, O. J. ; Maughan, T. (Contributor) ; Salto-Tellez, M. (Contributor) ; Quirke, P. (Contributor) ; Koelzer, V. (Contributor) ; Dunne, P. (Contributor) ; Beggs, A. (Contributor) ; Campbell, P. (Contributor) ; Buffa, F. (Contributor) ; Holmes, C. (Contributor) ; Kaplan, R. (Contributor) ; Brown, L. (Contributor) ; Lawler, M. (Contributor) ; Hordern, J. (Contributor) ; Tomlinson, I. (Contributor) ; Leedham, S. (Contributor) ; Morton, D. (Contributor)
Oncogenic BRAF, unrestrained by TGF?-receptor signalling, drives right-sided colonic tumorigenesis.
Nature Communications 12(1), 3464 (2021) [10.1038/s41467-021-23717-5]2021     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Ramesh, P. ; Lannagan, T. R. M. ; Jackstadt, R.-F.Extern* ; Atencia Taboada, L. ; Lansu, N. ; Wirapati, P. ; van Hooff, S. R. ; Dekker, D. ; Pritchard, J. ; Kirov, A. B. ; van Neerven, S. M. ; Tejpar, S. ; Kops, G. J. P. L. ; Sansom, O. J. ; Medema, J. P.
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer.
Cell death and differentiation 28(12), 3282 - 3296 (2021) [10.1038/s41418-021-00816-w]2021     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Krotenberg Garcia, A. ; Fumagalli, A. ; Le, H. Q. ; Jackstadt, R.-F.DKFZ* ; Lannagan, T. R. M. ; Sansom, O. J. ; van Rheenen, J. ; Suijkerbuijk, S. J. E.
Active elimination of intestinal cells drives oncogenic growth in organoids.
Cell reports 36(1), 109307 (2021) [10.1016/j.celrep.2021.109307]2021     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Hutton, C. ; Heider, F. ; Blanco-Gomez, A. ; Banyard, A. ; Kononov, A. ; Zhang, X. ; Karim, S. ; Paulus-Hock, V. ; Watt, D. ; Steele, N. ; Kemp, S. ; Hogg, E. K. J. ; Kelly, J. ; Jackstadt, R.-F.Extern* ; Lopes, F. ; Menotti, M. ; Chisholm, L. ; Lamarca, A. ; Valle, J. ; Sansom, O. J. ; Springer, C. ; Malliri, A. ; Marais, R. ; Pasca di Magliano, M. ; Zelenay, S. ; Morton, J. P. ; Jørgensen, C.
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity
Cancer cell 39(9), 1227 - 1244.e20 (2021) [10.1016/j.ccell.2021.06.017]2021   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article O'Connor, M. N. ; Kallenberg, D. M. ; Camilli, C. ; Pilotti, C. ; Dritsoula, A. ; Jackstadt, R.-F.Extern* ; Bowers, C. E. ; Watson, H. A. ; Alatsatianos, M. ; Ohme, J. ; Dowsett, L. ; George, J. ; Blackburn, J. W. D. ; Wang, X. ; Singhal, M.DKFZ* ; Augustin, H. G.DKFZ* ; Ager, A. ; Sansom, O. J. ; Moss, S. E. ; Greenwood, J.
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.
Med 2(11), 1231 - 1252.e10 (2021) [10.1016/j.medj.2021.10.002]2021   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Book/Journal Article Jackstadt, R.-F.Extern* ; Kaller, M. ; Menssen, A.DKFZ* ; Hermeking, H.DKFZ*
Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing.
Methods in molecular biology 2318, 119-160 (2021) [10.1007/978-1-0716-1476-1_7]2021   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jackstadt, R.-F. (First author)DKFZ* ; Norman, J. C.
Stromal WNTer Keeps the Tumor Cold and Drives Metastasis.
Developmental cell 56(1), 3 - 4 (2021) [10.1016/j.devcel.2020.12.011]2021   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Lannagan, T. R. ; Jackstadt, R.DKFZ* ; Leedham, S. J. ; Sansom, O. J.
Advances in colon cancer research: in vitro and animal models.
Current opinion in genetics & development 66, 50 - 56 (2021) [10.1016/j.gde.2020.12.003]2021   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Najumudeen, A. K. ; Ceteci, F. ; Fey, S. K. ; et al
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Nature genetics 53(1), 16 - 26 (2021) [10.1038/s41588-020-00753-3]2021   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Jackstadt, R.-F.Extern* ; Hodder, M. C. ; Sansom, O. J.
WNT and ?-Catenin in Cancer: Genes and Therapy
Annual review of cancer biology 4(1), 177 - 196 (2020) [10.1146/annurev-cancerbio-030419-033628]2020   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Schmidt, S. ; Gay, D. ; Uthe, F. W. ; Denk, S. ; Paauwe, M. ; Matthes, N. ; Diefenbacher, M. E. ; Bryson, S. ; Warrander, F. C. ; Erhard, F. ; Ade, C. P. ; Baluapuri, A. ; Walz, S. ; Jackstadt, R.-F.Extern* ; Ford, C. ; Vlachogiannis, G. ; Valeri, N. ; Otto, C. ; Schülein-Völk, C. ; Maurus, K. ; Schmitz, W. ; Knight, J. R. P. ; Wolf, E. ; Strathdee, D. ; Schulze, A. ; Germer, C.-T. ; Rosenwald, A. ; Sansom, O. J. ; Eilers, M. ; Wiegering, A.
A MYC-GCN2-eIF2? negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
Nature cell biology 21(11), 1413 - 1424 (2019) [10.1038/s41556-019-0408-0]2019     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Gay, D. M. ; Ridgway, R. A. ; Müller, M. ; Hodder, M. C. ; Hedley, A. ; Clark, W. ; Leach, J. D. ; Jackstadt, R.-F.Extern* ; Nixon, C. ; Huels, D. J. ; Campbell, A. D. ; Bird, T. G. ; Sansom, O. J.
Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.
Nature Communications 10(1), 723 (2019) [10.1038/s41467-019-08586-3]2019     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jackstadt, R.-F.Extern* ; van Hooff, S. R. ; Leach, J. D. ; Cortes-Lavaud, X. ; Lohuis, J. O. ; Ridgway, R. A. ; Wouters, V. M. ; Roper, J. ; Kendall, T. J. ; Roxburgh, C. S. ; Horgan, P. G. ; Nixon, C. ; Nourse, C. ; Gunzer, M. ; Clark, W. ; Hedley, A. ; Yilmaz, O. H. ; Rashid, M. ; Bailey, P. ; Biankin, A. V. ; Campbell, A. D. ; Adams, D. J. ; Barry, S. T. ; Steele, C. W. ; Medema, J. P. ; Sansom, O. J.
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Cancer cell 36(3), 319 - 336 (2019) [10.1016/j.ccell.2019.08.003]2019     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jaeckel, S. ; Kaller, M. ; Jackstadt, R.-F.Extern* ; Götz, U. ; Müller, S. ; Boos, S. L.DKFZ* ; Horst, D.DKFZ* ; Jung, P.DKFZ* ; Hermeking, H. (Last author)DKFZ*
Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells.
Nature Communications 9(1), 3573 (2018) [10.1038/s41467-018-06001-x]2018     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jackstadt, R.-F.Extern* ; Sansom, O. J.
The Wae to repair: prostaglandin E2 (PGE2) triggers intestinal wound repair.
The EMBO journal 36(1), 3 - 4 (2017) [10.15252/embj.201695973]2017     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Jackstadt, R.-F.Extern* ; Sansom, O. J.
Mouse models of intestinal cancer.
The journal of pathology 238(2), 141 - 151 (2016) [10.1002/path.4645]2016     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article (Review Article) Jackstadt, R.-F.Extern* ; Hermeking, H.
MicroRNAs as regulators and mediators of c-MYC function.
Biochimica et biophysica acta / Gene regulatory mechanisms 1849(5), 544 - 553 (2015) [10.1016/j.bbagrm.2014.04.003]2015   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Ormanns, S. ; Altendorf-Hofmann, A. ; Jackstadt, R.-F.Extern* ; Horst, D. ; Assmann, G. ; Zhao, Y. ; Bruns, C. ; Kirchner, T. ; Knösel, T.
Desmogleins as prognostic biomarkers in resected pancreatic ductal adenocarcinoma.
British journal of cancer 113(10), 1460 - 1466 (2015) [10.1038/bjc.2015.362]2015     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Cernat, L. ; Blaj, C. ; Jackstadt, R.-F.Extern* ; Brandl, L. ; Engel, J. ; Hermeking, H. ; Jung, A. ; Kirchner, T. ; Horst, D.
Colorectal cancers mimic structural organization of normal colonic crypts.
PLOS ONE 9(8), e104284 (2014) [10.1371/journal.pone.0104284]2014     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Shi, L. ; Jackstadt, R.-F.Extern* ; Siemens, H. ; Li, H. ; Kirchner, T.DKFZ* ; Hermeking, H. (Last author)DKFZ*
p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer.
Cancer research 74(2), 532 - 542 (2014) [10.1158/0008-5472.CAN-13-2203]2014   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Rokavec, M. ; Öner, M. G. ; Li, H. ; Jackstadt, R.-F.Extern* ; Jiang, L. ; Lodygin, D. ; Kaller, M. ; Horst, D. ; Ziegler, P. K. ; Schwitalla, S. ; Slotta-Huspenina, J.DKFZ* ; Bader, F. G. ; Greten, F. R.DKFZ* ; Hermeking, H. (Last author)DKFZ*
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis.
The journal of clinical investigation 124(4), 1853 - 1867 (2014) [10.1172/JCI73531]2014     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jackstadt, R.-F.Extern* ; Hermeking, H. (Last author)DKFZ*
AP4 is required for mitogen- and c-MYC-induced cell cycle progression.
OncoTarget 5(17), 7316 - 7327 (2014) [10.18632/oncotarget.2348]2014     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Siemens, H. ; Neumann, J. ; Jackstadt, R.-F.Extern* ; Mansmann, U. ; Horst, D. ; Kirchner, T. ; Hermeking, H.
Detection of miR-34a promoter methylation in combination with elevated expression of c-Met and ?-catenin predicts distant metastasis of colon cancer.
Clinical cancer research 19(3), 710 - 720 (2013) [10.1158/1078-0432.CCR-12-1703]2013   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Siemens, H. ; Jackstadt, R.-F.Extern* ; Kaller, M. ; Hermeking, H.
Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness.
OncoTarget 4(9), 1399 - 1415 (2013) [10.18632/oncotarget.1202]2013     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jackstadt, R.-F.Extern* ; Röh, S. ; Neumann, J. ; Jung, P. ; Hoffmann, R. ; Horst, D. ; Berens, C. ; Bornkamm, G. W. ; Kirchner, T. ; Menssen, A. ; Hermeking, H.
AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer.
Journal of experimental medicine 210(7), 1331 - 1350 (2013) [10.1084/jem.20120812]2013     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Contribution to a book Jackstadt, R.-F.Extern* ; Menssen, A. ; Hermeking, H.
Genome-wide analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA binding by next-generation sequencing.
2013The Myc Gene / Soucek, Laura (Editor) ; Totowa, NJ : Humana Press, 2013, Chapter 11 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-62703-428-9=978-1-62703-429-6 ; doi:10.1007/978-1-62703-429-6 Totowa, NJ : Humana Press, Methods in Molecular Biology 1012, 145 - 185 (2013) [10.1007/978-1-62703-429-6_11]2013   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Hahn, S. ; Jackstadt, R.-F.Extern* ; Siemens, H. ; Hünten, S. ; Hermeking, H.
SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition
The EMBO journal 32(23), 3079 - 3095 (2013) [10.1038/emboj.2013.236]2013   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Jackstadt, R.-F.Extern* ; Jung, P. ; Hermeking, H.
AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation.
Cell death & disease 4(8), e775 (2013) [10.1038/cddis.2013.282]2013     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Kriegl, L. ; Jung, A. ; Horst, D. ; Rizzani, A. ; Jackstadt, R.-F.Extern* ; Hermeking, H. ; Gallmeier, E. ; Gerbes, A. L. ; Kirchner, T. ; Göke, B. ; De Toni, E. N.
Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.
PLOS ONE 7(12), e51654 (2012) [10.1371/journal.pone.0051654]2012     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Drexler, S. K. ; Bonsignore, L. ; Masin, M. ; Tardivel, A. ; Jackstadt, R.-F.Extern* ; Hermeking, H. ; Schneider, P. ; Gross, O. ; Tschopp, J. ; Yazdi, A. S.
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 109(45), 18384 - 18389 (2012) [10.1073/pnas.1209171109]2012     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Liffers, S.-T. ; Maghnouj, A. ; Munding, J. B. ; Jackstadt, R.-F.Extern* ; Herbrand, U. ; Schulenborg, T. ; Marcus, K. ; Klein-Scory, S. ; Schmiegel, W. ; Schwarte-Waldhoff, I. ; Meyer, H. E. ; Stühler, K. ; Hahn, S. A.
Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3?.
BMC cancer 11(1), 137 (2011) [10.1186/1471-2407-11-137]2011     Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Siemens, H. ; Jackstadt, R.-F.Extern* ; Hünten, S. ; Kaller, M. ; Menssen, A. ; Götz, U. ; Hermeking, H.
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions.
Cell cycle 10(24), 4256 - 4271 (2011) [10.4161/cc.10.24.18552]2011   BibTeX | EndNote: XML, Text | RIS

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Journal Article Kriegl, L. ; Jung, A. ; Engel, J. ; Jackstadt, R.-F.Extern* ; Gerbes, A. L. ; Gallmeier, E. ; Reiche, J. A. ; Hermeking, H. ; Rizzani, A. ; Bruns, C. J. ; Kolligs, F. T. ; Kirchner, T. ; Göke, B. ; De Toni, E. N.
Expression, cellular distribution, and prognostic relevance of TRAIL receptors in hepatocellular carcinoma.
Clinical cancer research 16(22), 5529 - 5538 (2010) [10.1158/1078-0432.CCR-09-3403]2010   BibTeX | EndNote: XML, Text | RIS