PD Dr. Michael Hoffmeister
Funktion:
Stellvertretender Abteilungsleiter, Gruppenleiter
Kontakt:
Telefonnr.:
+49 (0)6221 42-1303
Fax:
+49 (0)6221 42-1302
Gebäude:
Im Neuenheimer Feld 581
Raum:
S 1.200
Stellvertretender Abteilungsleiter
Gruppenleiter "Molekular-pathologische Epidemiologie"
Gruppenleiter "Molekular-pathologische Epidemiologie"
Forschungsschwerpunkte
Darmkrebsprävention
Screening
Risikofaktoren und prognostische Faktoren
Molekular-pathologische Epidemiologie
Wissenschaftliche Studien, Projekte, Aktivitäten
DACHS-Studie, Principal Investigator (seit 2011)
IMPACT Konsortium, Netzwerkkoordinator (seit 2009), Co-Principal Investigator
KolosSal-Studie, Co-Principal Investigator (seit 2009)
SAMS-Studie, Co-Principal Investigator (seit 2012)
GECCO Consortium (Seattle, USA), Co-Investigator (seit 2009)
RAPS-Studie, Co-Investigator (seit 2014)
DARIO-Studie, Co-Investigator (seit 2015)
Gewähltes Mitglied des Wissenschaftlichen Rats des DKFZ (seit 2015)
Aktuelle Gruppenmitglieder MPE
Elizabeth Alwers, MD
Efrat Amitay, PhD
Prudence Carr, PhD
Margherita D'Errico, MSc
Stefanie Bienert, MSc
Min Jia, PhD
Publikationen
Ausgewählte Publikationen
Screening
Hoffmeister M, Holleczek B, Stock C, Zwink N, Stolz T, Stegmaier C, Brenner H. Utilization and determinants of follow-up colonoscopies within 6 years after screening colonoscopy: prospective cohort study. Int J Cancer 2019;144(2):402-10
The IARC Perspective on Colorectal Cancer Screening. N Engl J Med 2018;378(18):1734-40
Screening for Bowel Cancer: Increasing Participation via Personal Invitation. Dtsch Arztebl Int 2017;114(6):87-93
Brenner H, Stock C, Hoffmeister M. Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies. BMJ 2014;348:g2467
Brenner H, Chang-Claude J, Jansen L, Knebel P, Stock C, Hoffmeister M. Reduced risk of colorectal cancer up to 10 y after screening, surveillance, or diagnostic colonoscopy. Gastroenterology 2014;146(3);709-17
Risikofaktoren und prognostische Factoren
Gastroenterology 2018;155(6):1805-15 Healthy Lifestyle Factors Associated With Lower Risk of Colorectal Cancer Irrespective of Genetic Risk.
Clin Gastroenterol Hepatol 2018, doi: 10.1016/j.cgh.2018.11.036. [Epub ahead of print] Association Between Intake of Red and Processed Meat and Survival in Patients With Colorectal Cancer in a Pooled Analysis.
Hoffmeister M, Jansen L, Rudolph A, Toth C, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H. Statin use and survival after colorectal cancer: the importance of comprehensive confounder adjustment. J Natl Cancer Inst 2015;107(6):djv045
Carr PR, Walter V, Brenner H, Hoffmeister M. Meat subtypes and their association with colorectal cancer: systematic review and meta-analysis. Int J Cancer 2015;138(2):293-302
Molekular-pathologische Epidemiologie
JClin Epigenetics 2019;11(1):109. A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival.
Nat Med 2019;25(7):1054-56 Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.
J Natl Cancer Inst 2019;111(5):475-83
Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review. Clin Gastroenterol Hepatol 2019;17(3):402-10
The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage. Clin Gastroenterol Hepatol 2019;17(3):455-62 (*equal contribution)
Lifestyle factors and risk of sporadic colorectal cancer by microsatellite instability status: a systematic review and meta-analyses. Ann Oncol 2018;29(4):825-34 (*equal contribution)
Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes.