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Computational Epigenomics


  1. Schramm A, Köster J, Assenov Y, Althoff K, Peifer M, Mahlow E, Odersky A, Beisser D, Ernst C, Henssen AG, Stephan H, Schröder C, Heukamp L, Engesser A, Kahlert Y, Theissen J, Hero B, Roels F, Altmüller J, Nürnberg P, Astrahantseff K, Gloeckner C, De Preter K, Plass C, Lee S, Lode HN, Henrich KO, Gartlgruber M, Speleman F, Schmezer P, Westermann F, Rahmann S, Fischer M, Eggert A, Schulte JH. Mutational dynamics between primary and relapse neuroblastomas. Nature Genetics, doi:10.1038/ng.3349 (abstract)
  2. Liesenfeld DB, Habermann N, Toth R, Owen RW, Frei E, Böhm Ü, Schrotz-King P, Klika KD, Ulrich CM. Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare). Metabolomics, 11(4):998-1012 (abstract)


  1. Kunz J, Bandapalli OR, Rausch T, Stuetz A, Pechanska P, Assenov Y, Eilers J, Orlova E, Sagi J, Stanulla M, Schrappe M, Handgretinger R, Kirschner-Schwabe R, Hof J, Eckert C, Avigad S, Koehler R, Muckenthaler MU, Korbel J, Kulozik AE. Targeted Deep Sequencing of Genetic Alterations Identified By Whole Exome Sequencing Reveals Clonal Evolution in Pediatric T-Lymphoblastic Leukemia. Blood, 124(21):491-491 (abstract)
  2. Ecsedi S, Hernandez-Vargas H, Lima SC, Vizkeleti L, Toth R, Lazar V, Koroknai V, Kiss T, Emri G, Herceg Z, Adany R, Balazs M. DNA methylation characteristics of primary melanomas with distinct biological behaviour. PLoS ONE, 9(5):e96612 (abstract)
  3. Assenov Y*, Müller F*, Lutsik P*, Walter J, Lengauer T, Bock C. Comprehensive analysis of DNA methylation data with RnBeads. Nature Methods, 11(11):1138-1140 (abstract)
  4. Brocks D, Assenov Y, Minner S, Bogatyrova O, Simon R, Koop C, Oakes CC, Zucknick M, Lipka DB, Weischenfeldt J, Feuerbach L, Cowper-Sal R, Lupien M, Brors B, Korbel J, Schlomm T, Tanay A, Sauter G, Gerhäuser C, Plass C. Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer. Cell Reports, 8(3):798-806 (abstract)
  5. Oakes CC, Claus R, Gu L, Assenov Y, Hüllein J, Zucknick M, Bieg M, Brocks D, Bogatyrova O, Schmidt CR, Rassenti L, Kipps TJ, Mertens D, Lichter P, Döhner H, Stilgenbauer S, Byrd JC, Zenz T, Plass C. Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia. Cancer Discovery 4(3):348-361 (abstract)

















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