2016

Brenner H, Castro FA, Eberle A, Emrich K, Holleczek B, Katalinic A, Jansen L., for the GEKID Cancer Survival Workgroup. Death certificate only proportions should be age adjusted in studies comparing cancer survival across populations and over time. European Journal of Cancer 2016; 52:102-108.

Thompson DJ, O'Mara TA, Glubb DM, Painter JN, Cheng T, ..., Brenner H, ..., Tomlinson I, Dowsett M, Easton DF, Spurdle AB. CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer. Endocrine-Related Cancer 2016; 23:77-91.

Florath I, Butterbach K, Heiss JA, Bewerunge-Hudler M, Zhang Y, Schöttker B, Brenner H. Type 2 diabetes and leucocyte DNA methylation: An epigenome-wide association study in over 1500 older adults. Diabetologia 2016; 59:130-138.

Zhang Y, Schöttker B, Florath I, Stock C, Butterbach K, Holleczek B, Mons U, Brenner H. Smoking-associated DNA methylation biomarkers and their predictive value for all-cause and cardiovascular mortality. Environmental Health Perspectives 2016; 124:67-74.

Carr PR, Jansen L, Walter V, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M. Association of red and processed meat with survival after colorectal cancer and differences according to timing of dietary assessment. American Journal of Clinical Nutrition 2016; 103:192-200.

Mons U, Muscat JE, Modesto J, Richie JP, Brenner H. Effect of smoking reduction and cessation on the plasma levels of the oxidative stress biomarker glutathione - post-hoc analysis of data from a smoking cessation trial. Free Radical Biology & Medicine 2016; 91:172-177.

Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier C, Brenner H. Body mass index and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort. Experimental Gerontology 2016; 74:1-8.

Phipps A, Passarelli MN, Chan AT, Harrison TA, Jeon J, Hutter CM, Berndt SI, Brenner H, Caan BJ, Campbell PT, Chang-Claude J, Chanock SJ, Cheadle JP, Curtis KR, Duggan D, Fisher D, Fuchs CS, Gala M, Giovannucci EL, Hayes RB, Hoffmeister M, Hsu L, Jacobs EJ, Jansen L, Kaplan R, Kap L, Maughan TS, Potter JD, Schoen RE, Seminara D, Slattery ML, West H, White E, Peters U, Newcomb PA. Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis. Carciogenesis 2016; 37:87-95.

Carr P, Walter V, Brenner H, Hoffmeister M. Meat subtypes and their association with colorectal cancer: systematic reveiw and meta-analysis. International Journal of Cancer 2016; 138:293-302.

Schöttker B, Saum KU, Jansen EHJM, Holleczek B, Brenner H. Associations of metabolic, inflammatory and oxidative stress markers with total morbidity and multi-morbidity in a large cohort of older German adults. Age and Ageing 2016; 45:127-135.

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, ..., Brenner H, ..., Butterbach K, ..., Köttgen A, Kao L, Fox CS. Genetic association at 53 loci highlight cell types and biologic pathways for kidney function. Nature Communications 2016; 7:10023.

Haug U, Rösch T, Hoffmeister M, Katalinic A, Brenner H, Becker N. Einführung eines organisierten Darmkrebs-Screenings in Deuschland: Chancen und Herausforderungen. Das Gesundheitswesen (in press).

Purrington KS, Slettedahl S, Bolla MK, ..., Brenner H, ..., Dieffenbach AK, Stegmaier C, Arndt V, ..., Slager S, Vachon CM, Couch FJ. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. Human Molecular Genetics (in press).

von Winterfeld M, Hoffmeister M, Ingold-Heppner B, Jansen L, Tao S, Herpel E, Schirmacher P, Dietel M, Chang-Claude J, Autschbach F, Brenner H, Bläker H. Frequency of therapy-relevant staging shifts in colorectal cancer through the introduction of pN1c in the 7th TNM edition. European Journal of Cancer (in press).

Bock JO, Heider D, Matschinger H, Brenner H, Saum KU, Haefeli WE, König HH. Willingness to pay for health insurance among the elderly population in Germany. European Journal of Health Economics (in press).

Chen XZ, Chen H, Castro FA, Hu JK, Brenner H. Epstein-Barr virus infection and gastric cancer - a systematic review. Medicine (in press).

Hollestelle A, van der Baan F, Berchuck A, Johnatty SE, Aben KK, Agnarsson BA, ..., Arndt V, ..., Brenner H, ..., Pharoah PDP, Rookus MA, Hooning MJ, Goode EL. No clinical utility of KRAS Variant rs61764370 for ovarian or breast cancer. Gynecologic Oncology (in press).

Boehlen F, Herzog W, Maatouk I, Saum K-U, Brenner H, Wild B. Behandlungswünsche von älteren Menschen mit psychischen Erkrankungen. Zeitschrift für Gerontologie und Geriatrie (in press).

Pulte D, Jansen L, Castro FA, Emrich K, Katalinic A, Holleczek B, Brenner H, for the GEKID Cancer Survival Working Group. Trends in survival of multiple myeloma patients in Germany and in the United States in the first decade of the 21st century. British Journal of Haematology (in press).

Ordonez-Mena JM, Schöttker B, Fedirko V, Jenab M, Olsen A, Halkjær J, Kampman E, de Groot L, Jansen E, BAs Bueno-de-Mesquita H, Peeters PH, siganos G, Wilsgaard T, Perna L, Holleczek B, Pettersson-Kymmer U, Orfanos P, Trichopoulou A, Boffetta P, Brenner H. Pre-diagnostic vitamin D concentrations and cancer risks in older individuals: an analysis of cohorts participating in the CHANCES consortium. European Journal of Epidemiology (in press).

Jiao S, Peters U, Berndt S, Bézieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Lemire M, Newcomb PA, Potter JD; Slattery ML, Woods MO, Hsu L. Powerful set-based gene-environment interaction testing framework for complex diseases. Genetic Epidemiology (in press).

Zhang B, Shu XO, Delahanty RJ, Zeng C, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hunter DJ, Easton DF, Zheng W. Height and breast cancer risk: Evidence from prospective studies and mendelian randomization. Journal of the National Cancer Institute (in press).

Lüthgens K, Albert S, Brenner H. Unterschiedliche Nachweisgrenzen immunologischer Tests auf Blut im Stuhl unterstreichen die Notwendigkeit der Standardisierung und Qualitätssicherung. Zeitschrift für Gastroenterologie (in press).

Hajek A, Bock J-O, Brenner H, Saum K-U, Matschinger H, Haefeli WE, Quinzler R, Heider D, König H-H. Welche Faktoren beeinflussen die privaten Zuzahlungen zu Gesundheitsleistungen im Alter? Ergebnisse einer Längsschnittstudie. Das Gesundheitswesen (in press).

Brenner H, Jansen L. Timely disclosure of progress in long-term cancer survival: The boomerang method substantially improved estimates in a comparative study. Journal of Clinical Epidemiology (in press).

Meeks HD, Song H, Michailidou K, Bolla MK, Dennis J, ..., Brenner H, Butterbach K, ..., Couch FJ, Spurdle AB, Goldgar DE. BRCA2 polymorphic stop codon K3326X and the risk of breast, prostate and ovarian cancers. Journal of the National Cancer Institute (in press).

Eberle A, Jansen L, Krilaviciute A, Luttmann S, Emrich K, Holleczek B, Nennecke A, Katalinic A, Brenner H, for the GEKID Cancer Survival Working Group. Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients. Lung Cancer (in press).

Benner A, Hoffmeister M, Jansen L, Yang R, Bläker H, Herpel E, Ulrich A, Ulrich CM, Chang-Claude J, Brenner H, Burwinkel B. Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy. Genomics (in press).

Holleczek B, Brenner H. Implications from under-reporting, death certificate notifications and trace-back on the recorded incidence of a newly established population-based cancer registry. Methods of Information in Medicine (in press).

Brück K, Stel VS, Gambaro G, Hallan S, Völzke H, Ärnlöv J, Kastarinen M, Guessous I, Vinhas J, Stengel B, Brenner H, Chudek J, Romundstad S, Tomson C, Gonzalez AO, Bello AK, Ferrieres J, Palmieri L, Browne G, Capuano V, Van Biesen W, Zoccali C, Gansevoort R, Navis G, Rothenbacher D, Ferraro PM, Nitsch D, Wanner C, Jager KJ. Chronic kidney disease prevalence varies across European general population. Journal of the American Society of Nephrology (in press).

Werner S, Krause F, Rolny V, Strobl M, Morgenstern D, Datz C, Chen H, Brenner H. Evaluation of a 5-marker blood test for colorectal cancer early detection in a colorectal cancer screening setting. Clinical Cancer Research (in press).

Teumer A, Tin A, Sorice R, Gorski M, Yeo NC, ..., Dieffenbach AK, ..., Brenner H, ..., Butterbach K, ..., Böger CA, Fox CS, Pattaro C, Köttgen A. Genome-wide association studies identify genetic loci associated with albuminuria in diabetes. Diabetes (in press).

Sirri E, Castro F, Kieschke J, Jansen L, Emrich K, Gondos A, Holleczek B, Katalinic A, Urbschat I, Vohmann C, Brenner H for the GEKID Cancer Survival Group. Recent trends in survival of patients with pancreas cancer in Germany and the United States. Pancreas (in press).

Garcia-De-Albeniz X, Rudolph A, Hutter C, White E, Lin Y, ..., Brenner H, ..., Hoffmeister M, Butterbach K, ..., Hsu L, Chan A, Peters U, Chang-Claude J. CYP24A1 variant modifies the association between use of estrogen plus progestogen therapy and colorectal cancer. British Journal of Cancer (in press).

Eisemann N, Jansen L, Castro FA, Chen T, Eberle A, Nennecke A, Zeissig SR, Brenner H, Katalinic A, for the GEKID Cancer Survival Working Group. Survival from non-melanoma skin cancer in Germany. British Journal of Dermatology (in press).

O'Doherty MG, Cairns K, O'Neill V, Lamrock F, Jørgensen T, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kuulasmaa K, Boffetta P, Trichopoulou A, Kee F, on behalf of the CHANCES consortium. Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES). European Journal of Epidemiology (in press).

Easton DF, Lesueur F, Decker B, Michailidou K, Li J, ..., Arndt V, ..., Brenner H, ..., Le Calvez-Kelm F, Goldgar DE, Tavtigian SV, Chenevix-Trenche G. No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing. Journal of Medical Genetics (in press).

Zwink N, Stock C, Birkner B, Hoffmeister M, Brenner H. Screening colonoscopy volume and detection of colorectal neoplasms: A state-wide study from Bavaria, Germany. European Journal of Cancer Prevention (in press).

Kap EJ, Seibold P, Scherer D, Habermann N, Balavarca Y, Jansen L, Zucknick M, Becker N, Hoffmeister M, Ulrich A, Benner A, Ulrich CM, Burwinkel B, Brenner H, Chang-Claude J. SNPs in transporter and metabolizing genes as predictive markers for oxaliplatin treatment in colorectal cancer patients. International Journal of Cancer (in press).

Gondos A, Jansen L, Heil J, Schneeweiss A, Voogd AC, Frisell J, Fredriksson I, Johannsson U, Tvedskof TF, Jensen MB, Balslev E, Hartmann-Johnsen OJ, Sant M, Baili P, Agresti R, van de Velde T, Broeks A, Nogaret JM, Bourgois P, Moreau M, Mátrai Z, Sávolt A, Nagy P, Kásler M, Schrotz-King P, Ulrich C, Brenner H. Time trends in axilla management among early breast cancer patients: persisting major variation in clinical practice across European centers. Acta Oncologica (in press).

Petridis C, Brook MN, Shah V, Kohut K, Gorman P, ..., Brenner H, Arndt V, ..., Tomlinson I, Roylance R, Garcia-Closas M, Sawyer EJ. Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Research (in press).

Dumstrei K, Chen H, Brenner H. A systematic review of serum autoantibodies as biomarkers for pancreatic cancer detection. Oncotarget (in press).

Brenner H, Schrotz-King P, Holleczek B, Katalinic A, Hoffmeister M. Rückgang der Darmkrebs-Inzidenz und -Mortalität in Deutschland in den ersten 10 Jahren nach Einführung der Vorsorge Koloskopie. Deutsches Ärzteblatt (in press).

Zhang Y, Florath I, Saum KU, Brenner H. Self-reported smoking, serum cotinine, and blood DNA methylation. Environmental Research (in press).

Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairlbäurl H, Kaminski MM, Penzel R, Zhang C, Fuller JC, Wade R Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W. The HMGB1 protein induces a metabolic type of tumor cell death by blocking aerobic respiration. Nature Communication (in press).

Florath I, Schöttker B, Butterbach K, Bewerunge-Hudler M, Brenner H. Epigenome-wide search for association of serum 25-hydroxyvitamin D concentration with leukocyte DNA methylation in a large cohort of older men. Epigenomics (in press).


Chen H, Knebel P, Brenner H. Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer in screening settings to limit the number of false positive findings. Journal of Clinical Epidemiology (in press).

Schöttker B, Rathmann W, Herder C, Thorand B, Wilsgaard T, Njølstad I, Siganos G, Mathiesen EB, Saum KU, Peasey A, Feskens E, Boffetta P, Trichopoulou A, Kuulasmaa KK, Kee F, Brenner H. HbA1c levels in non-diabetic older adults - No J-shaped associations with primary cardovascular events, cardiovascular and all-cause mortality after adjustment for confounders. A meta-analysis of individual participant data from six cohort studies. BMC Medicine (in press).

2015

Lin W-Y, Camp NJ, Ghoussaini M, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Dunning A, Easton DF, Cox A. Identification and characterisation of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Human Molecular Genetics 2015; 24:285-298.

Campa D, Martino A, Varkonyi J, Lesueur F, Jamrozial K, Landi S, Jurczyszyn  A, Marques H, Andersen V, Jurado M, Brenner H, Petrini M, Vogel U, Garcia-Sanz R, Buda G, Gemignani F, Rios R, Vangsted AJ, Dumontet C, Martinez-Lopez J, Moreno MJ, Stepien A, Watek M, Moreno V, Dieffenbach AK, Rossi AM, Butterbach K, Jacobsen SEH, Goldschmidt H, Sainz J, Hillengass J, Orciuolo E, Dudzinski M, Weinhold N, Reis RM, Canzian F. Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length. International Journal of Cancer 2015:136:E351-E358.

Conway DI, Brenner DR, McMahon AD, Macpherson LMD, Agudo A, Ahrens W, Bosetti C, Brenner H, ..., Müller H, ..., Lee YCA, Hashibe M, Brennan P. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries.International Journal of Cancer 2015; 136:1125-1139.

Elgizouli M, Logan C, Nieters A, Brenner H, Rothenbacher D. Cord blood PRF1 methylation patterns and risk of lower respiratory tract infections in infants: findings from the Ulm Birth Cohort. Medicine 2015; 94:e332.

Glubb DM, Maranian MJ, Michailidou K, Pooley KA, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, .., Dunning AM, French JD. Fine scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics 2015; 96:5-20.

Carvajal-Carmona L, O'Mara TA, Painter JN, ..., Brenner H, Dieffenbach AK, ..., Easton DF, Spurdle AB, Thompson DJ. Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Human Genetics 2015; 134:231-245.

Rudolph A, Milne RL, Truong T, ..., Dieffenbach AK, Arndt V, Stegmaier C, ..., Brenner H, ..., Pharoah PDP, Garcia-Closas M, Chang-Claude J. Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors. International Journal of Cancer 2015; 136:E685-E696.

GBD 2013 Mortality and Causes of Death Collaborators*. Global, regional and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015; 385:117-171. *Collaborators from DKFZ: Brenner H, Schöttker B.

Brenner H, Hoffmeister M, Birkner B, Stock C. Which adenomas are detected by fecal occult blood testing? A state-wide analysis from Bavaria, Germany. International Journal of Cancer 2015; 136:1672-1679.

Ashwin N, Ananthakrishnan AN, Du M, Berndt SI, Brenner H, Caan BJ, Casey G, Chang-Claude J, Duggan D, Fuchs CS, Gallinger S, Giovannucci EL, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hou L, Hsu L, Jenkins MA, Kraft P, Ma J, Nan H, Newcomb PA, Ogino S, Potter JD, Seminara D, Slattery ML, Thornquist M, White E, Wu K, Peters U, Chan AT. Red meat intake, NAT2, and risk of colorectal cancer: A pooled analysis of 11 studies. Cancer Epidemiology, Biomarkers and Prevention 2015; 24:198-205.

Dallmeier D, Pencina MJ, Rajman I, Koenig W, Rothenbacher D, Brenner H. Serial measurements of N-Terminal Pro-Brain Natriuretic Peptide in patients with coronary heart disease. PLoS One 2015; 10:e0117143.

Braig S, Brandt S, Wabitsch M, Florath I, Brenner H, Rothenbacher D, Genuneit J. Age-specific influence of wheezing phenotypes on preadolescent and adolescent health-related quality of life. Pediatric Allergy and Immunology 2015; 25:781-787.

Stock C, Uhlmann L, Hoffmeister M, Laux G, Kieser M, Brenner H. Identification of physicians with unusual performance in screening colonoscopy databases: a Bayesian approach. Gastrointestinal Endoscopy 2015; 81:646-654.

Kabisch M, Lorenzo Bermejo J, Dünnebier T, Ying S, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hamann U. Inherited variants in the inner contromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER negative breast cancer. Carcinogenesis 2015; 36:256-271.

Painter JN, O'Mara TA, Batra J, ..., Brenner H, Dieffenbach AK, ..., Edwards SL, Thompson DJ, Spurdle AB. Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. Human Molecular Genetics 2015; 24:1478-1492.

Yang R, Pfütze K, Zucknick M, Sutter C, Wappenschmidt B, Marma F, Qu B, Cuk K, Engel C, Schott S, Schneeweiss A, Brenner H, Claus R, Plass C, Bugert P, Hoth M, Sohn C, Schmutzler R, Bartram CR, Burwinkel B. DNA methylation array analyses identified breast cancer associated HYAL2 methylation in peripheral blood. International Journal of Cancer 2015; 136:1845-1855.

Bläker H, Hildebrandt B, Riess H, von Winterfeld M, Ingold-Heppner B, Roth W, Kloor M, Schirmacher P, Dietel M, Tao S, Jansen L, Chang-Claude J, Ulrich A, Brenner H, Hoffmeister M. Lymph node count and prognosis in colorectal cancer: the influence of examination quality. International Journal of Cancer 2015; 136:1957-1966.

Bickeböller M, Tagscherer K, Kloor M, Jansen L, Chang-Claude J, Brenner H, Hoffmeister M, Toth C, Schirmacher P, Roth W, Bläker H. Functional characterization of the tumor suppressor MARCKS in colorectal cancer and its association with survival. Oncogene 2015; 34:1150-1159.

Bozorgmehr K, San Sebastian M, Brenner H, Razum O, Maier W, Saum KU, Holleczek B, Miksch A, Szecsenyi J. Analysing horizontal equity in enrolment in Disease Management Programmes for coronary heart disease in Germany 2008 - 2010. International Journal for Equity in Health 2015; 14:28.

Jansen L, Castro F, Gondos A, Krilaviciute A, Barnes B, Eberle A, Emrich K, Hentschel S, Holleczek B, Katalinic A, Brenner H for the GEKID Cancer Survival Workgroup. Recent cancer survival in Germany: an analysis of common and less common cancers. International Journal of Cancer 2015; 136:2649-2658.

Allemani C, Weir HK, ..., Tucker TC, Coleman MP, Concord Working Group*. Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,877 patients from 279 population-based registries in 67 countries (CONCORD-2). The Lancet 2015; 385:977-1010. *Member of the CONCORD Working Group from DKFZ: Brenner H.

Heiss JA, Brenner H. Between-array normalization for 450K data. Frontiers in Genetics 2015; 6:92.

Brandt S, Moß A, Koenig W, Rothenbacher D, Brenner H, Wabitsch M. Intrafamilial  associations of cardiometabolic risk factors - results of the Ulm Birth Cohort Study. Atherosclerosis 2015; 240:174-183.

Nan H, Hutter CM, Lin Y, Jacobs EJ, Ulrich CM, White E, Baron JA, Berndt SI, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chang-Claude J, Chanock SJ, Cotterchio M, Duggan D, Figueiredo JC, Fuchs CS, Giovannucci EL, Gong J, Haile RW, haarrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jenkins MA, Jiao S, Lindor NM, Lemire M, Le Marchand L, Newcomb PA, Ogino S, Pflugeisen BM, Potter JD, Qu C, Rosse SA, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Thibodeau SN, Thomas F, Thornquist M, Warnick GS, Zanke BW, Gauderman J, Peters U Hsu L, Chan AT; for the CCFR and GECCO. Association of Aspirin and NSAID use with risk of colorectal cancer according genetic variants. JAMA 2015; 313:1133-1142.

Michailidou K, Beesley J, Lindstrom S, Canisius S, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hall P, Easton DF. Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Nature Genetics 2015; 47:373-381.

Stegeman S, Amankwah E, Klein K, O'Mara TA, Kim D, Lin HY, Permuth-Wey J, Sellers TA, Srinivasan S, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pharoah P, Khaw KT, Standford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Teixeria MR, Consortium P, Bioresource AP, Spurdle AB, Clements JA, Park JY, Batra J. A large scale analysis of genetic variants within putative miRNA binding sites in prostate cancer. Cancer Discovery 2015; 5:368-379.

Brenner H, Altenhofen L, Stock C, Hoffmeister M. Prevention, early detection, and overdiagnosis of colorectal cancer within 10 years of screening colonoscopy in Germany. Clinical Gastroenterology and Hepatology 2015; 13:717-723.

Emrich IE, Pickering J, Schöttker B, Lennartz CS, Rogacev KS, Brenner H, Rothenbacher D, Holleczek B, Saum KU, Fliser D, Heine GH. Comparison of the performance of two GFR Estimating Equations using creatinine and cystatin C to predict adverse outcomes in elderly individuals. Americal Journal of Kidney Diseases 2015; 65:632-638.

Schöttker B, Saum KU, Jansen EHJM, Boffetta P, Trichopoulou A, Holleczek B, Dieffenbach AK, Brenner H. Oxidative stress markers and all-cause mortality at older age. A population-based cohort study. Journal of Gerontology: Medical Sciences 2015; 70:518-524.

Schmidt ME, Chang-Claude J, Seibold P, Vrieling A, Heinz J, Flesch-Janys D, Steindorf K: Determinants of long-term fatigue in breast cancer survivors: results of a prospective patient cohort study. Psychooncology 2015; 24(1): 40-6.

Scharhag-Rosenberger F, Kuehl R, Klassen O, Schommer K, Schmidt ME, Ulrich CM, Wiskemann J, Steindorf K: Exercise training intensity prescription in breast cancer survivors: validity of current practice and specific recommendations. Journal of Cancer Survivorship 2015; 137(2):471-80.

Scharhag-Rosenberger F, Wiskemann J, Scharhag J: Cardiopulmonary exercise testing in cancer patients: should we really refrain from considering it for preparticipation screening? Oncologist 2015; 20(2): 228.

Ungar N, Sieverding M, Ulrich CM, Wiskemann J (2015): What explains the intention to be physically active in cancer patients? Different determinants for active and insufficiently active patients. J Psychosoc Oncol. 33(1):15-33.

Werner S, Chen H, Tao S, Brenner H. Systematic Review: Serum autoantibodies in the early detection of gastric cancer. International Journal of Cancer 2015; 136:2243-2252.

Rothenbacher D, Jaensch A, Mons U, Hahmann H, Becker T, Koenig W, Brenner H. Prognostic value of one-year course of symptoms of anxiety and depression in patients with coronary heart disease: role of physical activity and unmet medical need. European Journal of Preventive Cardiology 2015; 22:1129-1138.

Chen H, Chen XZ, Waterboer T, Castro FA, Brenner H. Viral infections and colorectal cancer: a systematic review of epidemiological studies. International Journal of Cancer 2015; 137:12-24.

Vart P, Bakker SJL, Schöttker B, de Zeeuw D, Rothenbacher D, Brenner H, Lambers Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U, Koenig W, Gansevoort RT. Relevance of correction for drift and day-to-day variation in cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with independent replication in the ESTHER cohort. Clinical Chemistry and Laboratory Medicine 2015; 53:1381-1390.

Perna L, Wahl HW, Mons U, Saum KU, Holleczek B, Brenner H. Cognitive impairment, all-cause and cause-specific mortality among non-demented older adults. Age and Ageing 2015; 44:445-451.

Boehlen F, Herzog W, Quinzler R, Haefeli WE, Maatouk I, Niehoff D, Saum KU, Brenner H, Wild B. Loneliness in the elderly is associated with the use of psychotropic drugs. International Journal of Geriatric Psychiatry 2015; 30:957-964.

Song M, Gong J, Giovannucci EL, ..., Brenner H, Chang-Claude J, ..., Hoffmeister M, ..., Jensen M, Peters U, Chan AT. Genetic variants of adiponectin and risk of colorectal cancer. International Journal of Cancer 2015; 137:154-164.

Orr N, Dudbridge F, Dryden N, ..., Brenner H, Dieffenbach AK, Arndt V, ..., dos Santos Silva I, Fletcher O, Peto J. Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. Human Molecular Genetics 2015; 24:2966-2984.

Benetou V, Orfanos P, Feskanich D, Michaelsson K, Pettersson-Kymmer U, Ahmed L, Peasey A, Wolk A, Brenner H, Bobak M, Wilsgaard T, Schöttker B, Saum KU, Bellavia A, Grodstein F, Klinaki E, Valanou E, Papatesta HM, Boffetta P, Trichopoulou A. Education, marital status and risk of hip fractures in older men and women: the CHANCES project. Osteoporosis International 2015; 26:1733-1746.

Kap EJ, Seibold P, Richter S, Scherer D, Habermann N, Balavarca Y, Jansen L, Becker N, Pfuetze K, Popanda O, Hoffmeister M, Ulrich A, Benner H, Ulrich CM, Burwinkel B, Brenner H, Chang-Claude J. Genetic variants in DNA repair genes as potential predictive markers for oxaliplatin chemotherapy in colorectal cancer. The Pharmacogenomics Journal 2015; 15:505-512.

Mons U, Müezzinler A, Gellert C, Schöttker B, Abnet CC, Bobak M, de Groot L, Freedman ND, Jansen E, Kee F, Kromhout D, Kuulasmaa K, Laatikainen T, O'Doherty MG, Bueno-de-Mesquita B, Orfanos P, Peters A, van der Schouw YT, Wilsgaard T, Wolk A, Trichopoulou A, Bofetta P, Brenner H, on behalf of the CHANCES consortium. Impact of smoking and smoking cessation on cardiovascular events and mortality among older adults - Meta-analysis of individual participant data from prospective cohort studies of the CHANCES consortium. British Medical Journal 2015; 350:h1551.

Hsu L, Jeon J, Brenner H, Gruber SB, Schoen RE, Berndt SI, Chan AT, Chang-Claude J, Du M, Gong J, Harrison TA, Hayes RB, Hoffmeister M, Hutter CM, Lin Y, Nishihara R, Ogino S, Prentice RL, Schumacher FR, Seminara D, Slattery ML, Thomas DC, Thornquist M, Newcomb PA, Potter JD, Zheng Y, White E, Peters U on behalf of the Colorecal Transdisciplinary (CORECT) Study and Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). A model to determine colorectal cancer risk using common genetic susceptibility loci. Gastroenterology 2015; 148:1330-1339.

Hoffmeister M, Jansen L, Rudolph A, Toth C, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H. Statin use and survival after colorectal cancer: the importance of comprehensive confounder adjustment. Journal of the National Cancer Institute 2015; 107:djv045.

Saum KU, Dieffenbach AK, Jansen EHJM, Schöttker B, Holleczek B, Hauer K, Brenner H. Association between oxidative stress and frailty in an elderly German population: results from the ESTHER cohort study. Gerontology 2015; 61:407-415.

Pulte D, Jansen L, Brenner H. Survival disparities by insurance type for patients age 15-64 with Non-Hodgekin Lymphoma. The Oncologist 2015; 20:554-561.

Walter V, Jansen L, Hoffmeister M, Ulrich A, Chang-Claude J, Brenner H. Smoking and survival of colorectal cancer patients: population-based study from Germany. International Journal of Cancer 2015; 137:1433-1445.

Brenner H, Jansen L. Restriction to period of interest improves informative value of death certificate only proportions in period analysis of cancer survival. Journal of Clinical Epidemiology 2015; 68:1432-1439.

Zhang Y, Schöttker B, Ordonez-Mena J, Holleczek B, Yang R, Burwinkel B, Butterbach K, Brenner H. F2RL3 methylation, lung cancer incident and mortality. International Journal of Cancer 2015; 137:1739-1748.

Guo Q, Schmidt MK, Kraft P, Canisius S, ..., Brenner H, Dieffenbach AK, Arndt V, ..., Pharoah PDP. Identification of novel genetic markers of breast cancer survival. Journal of the National Cancer Institute 2015; 107:djv081.

Müezzinler A, Gellert C, Mons U, Schöttker B, Jansen E, Kee F, O'Doherty MG, Kuulasmaa K, Freedman ND, Abnet CC, Wolk A Håkansson N, Orsini N, Wilsgaard T, Njølstad I, Bøgeberg M, Leenders M, Bueno-de-Mesquita B, van der Schouw YT, Peeters PH, Streppel MT, de Groot LCPGM, Peters A, Schneider A, Orfanos P, Linneberg A, Pisinger C, Lorbeer R, Tamosiunas A, Baceviciene M, Luksiene D, Bernotiene G, Jousilahti P, Schaan B, Wennberg P, Petterson-Kymmer U, Jansson JH, Söderberg S, Eriksson S, jankovic N, Kromhout D, Geelen A, Sánchez M-J, Veronesi G, Trichopoulou A, Boffetta P, Brenner H. Smoking and all-cause mortality in older adults - Results from CHANCES Consortium. American Journal of Preventive Medicine 2015; 49:e53-e63.

Campa D, Rizzato C, Stolzenberg-Solomon R, Pacetti P, Vodicka P, Cleary S, Capurso G, Bas Bueno-de-Mesquita H, Werner J, Gazouli M, Butterbach K, Ivanauskas A, Giese N, Petersen GM, Fogar P, Wang Z, Bassi C, Ryska M, Theodoropoulos GE, Kooperberg C, Hassan M, Greenhalf W, Pasquali C, Hackert T, Fuchs C, Mohelníková-Duchoñová B, Sperti C, Funel N, Dieffenbach AK, Wareham NJ, Buring J, Holcátová I, Costello-Goldring E, Zambone C-F, Kupcinskas J, Risch HA, Kraft P, Bracci PM, Pezzilli R, Olson SH, Sesso H, Hartge P, Strobel O, Malecka-Panas E, Visvanathan K, Arslan AA, Pedrazzoli S, Sucek P, Gioffreda D, Key TJ, Talar-Wojnarowska R, Scarpa A, Mambrini A, Jacobs EJ, Jamroziak K, Klein A, Tavano F, Bambi F, Landi S, Austin MA, Vodickova L, Brenner H, Chanock SJ, Delle Fave G, Piepoli A, Cantore M, Zheng W, Wolpin B, Amundadottir L, Canzian F. The TERT gene harbors multiple variants associated with pancreatic cancer susceptibility. International Journal of Cancer 2015; 137:2175-2183.

Chen H, Zucknick M, Werner S, Brenner H. Head-to head comparison and evaluation of 92 plasma protein biomarkers for early detection of colorectal cancer in a true screening setting. Clinical Cancer Research 2015; 21:3318-3326.

Brenner H, Altenhofen L, Stock C, Hoffmeister M. Expected long-term impact of the German screening colonoscopy program on colorectal cancer prevention: analyses based on 4,407,971 screening colonoscopies. European Journal of Cancer 2015; 51:1346-1353.

Chen XZ, Chen H, Castro FA, Hu JK, Brenner H. Epstein-Barr virus infection and gastric cancer - a systematic review. Medicine 2015; 94(20):e792.

Al Olama AA, Benlloch S, Antoniou AC, Giles GG, Severi G, Neal D, Hamdy FC, Donovan JL, Muir K, Schleutker J, Henderson BE, Haiman C, Schumacher FR, Pashayan N, Pharoah PD, Ostrander EA, Stanford JL, Batra J, Clements JA, Chambers SK, Weischer M, Nordestgaard BG, Ingles SA, Sorensen KD, Orntoft TF, Park JY, Cybulski C, Maier C, Doerk T, Dickinson JL, Cannon-Albright L, Brenner H, Rebbeck TR, Zeigler -Johnson C, Habuchi T, Thibodeau SN, Cooney K, Chappius PO, Hutter P, Kaneva RP, Foulkes WD, Zeegers MP, Lu YJ, Zhang HW, Stephenson R, Cox A, Southey MC, Spurdle AB, FitzGerald L, Leongamornlert D, Saunders E, Tymrakiewicz M, Guy M, Dadaev T, Little SJ, Govindasami K, Sawyer E Wilkinson R, Herkommer K, Hopper JL, Lophatonanon A, Rinckleb AE, Kote-Jarai Z, Eeles RA, Easton DF. Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 unknown prostate cancer susceptibility loci. Cancer Epidemiology, Biomarkers and Prevention 2015; 24:1121-1129.

Darabi H, McCue K, Beesley J, Michailidou K, ..., Brenner H, ..., Arndt V, ..., Dunning AM, Easton DF, Hall P, Cevenix-Trench G. Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate NRBF2 expression. American Journal of Human Genetics 2015; 97:22-34.

Schumacher F, Schmit S, Jiao S, Edlund C, Wang H, ..., Butterbach K, ..., Brenner H, ... Hoffmeister M, ..., Casey G, Gruber S, Peters U. Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nature Communication 2015; 6:7138.

Pirie A, Guo Q, Kraft P, Canisius S, Eccles DM, ..., Brenner H, Butterbach K, Arndt V, ..., Fasching PA, Pharoah PDP, Schmidt MK. Common germline polymorphisms associated with breast cancer specific survival. Breast Cancer Research 2015; 17:58.

Global Burden of Disease Study 2013 Collaborators*. Global, regional, and national incidence, prevalence, and YLDs for 301 acute and chronic diseases and injuries for 188 countries, 1990-2013: a systematic analysis for the Global Burden of Diseases Study 2013. The Lancet 2015; 386:743-800. *Collaborators from DKFZ: Brenner H, Schöttker B.

Brenner H, Altenhofen L, Kretschmann J, Rösch T, Pox C, Stock C, Hoffmeister M. Trends in adenoma detection rates during the first 10 years of the German screening colonoscopy program. Gastroenterology 2015; 149:356-366.

Kahlert C, Lerbs T, Pecqueux M, Herpel E, Hoffmeister M, Jansen L, Brenner H, Chang-Claude J, Bläker H, Kloor M, Roth W, Pilarsky C, Rahbari NN, Schölch S, Bork U, Reissfelder C, Weitz J, Aust D, Koch M. Overexpression of SIX1 is an independent prognostic marker in stage I - III colorectal cancer. International Journal of Cancer 2015; 137:2104-2113.

Beyerle J, Frei E, Stiborova M, Habermann N, Ulrich CM. Biotransformation of xenobiotics in the human colon and rectum and its associations with colorectal cancer. Drug Metab Rev 2015; 47(2):199-221.

Wiskemann J, Kleindienst N, Kuehl R, Dreger P, Schwerdtfeger R, Huber G, Bohus M. Effects of a physical exercise on survival after allogeneic stem cell transplantation. International Journal of Cancer 2015; 137(11):2749-56.

Schmidt ME, Wiskemann J, Armbrust P, Schneeweiss A, Ulrich CM, Steindorf K: Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: A randomized controlled trial. International Journal of Cancer 2015; 137(2), 471-480.

Gollhofer SM, Wiskemann J, Schmidt ME, Klassen O, Ulrich CM, Oelmann J, Hof H, Potthoff K, Steindorf K (2015): Factors influencing participation in a randomized controlled resistance exercise intervention study in breast cancer patients during radiotherapy. BMC Cancer, 15(1):186.

Skender S, Schrotz-King P, Böhm J, Abbenhardt C, Gigic B, Chang-Claude, J, Siegel EM, Steindorf, K, Ulrich, CM. Repeat physical activity measurement by accelerometry among colorectal cancer patients—feasibility and minimal number of days of monitoring. BMC Research Notes 2015; 8:222.

Kharazmi E, Fallah M, Pukkala E, Olsen JH, Tryggvadottir L, Sundquist K, Tretli S, Hemminki K. Risk of familial classical Hodgkin lymphoma by relationship, histology, age, and sex: a joint study from five Nordic countries. Blood 2015; 126(17): 1990-5.

Kharazmi E, Hemminki K, Pukkala E, Sundquist K, Tryggvadottir L, Tretli S, Olsen JH, Fallah M. Cancer Risk in Relatives of Testicular Cancer Patients by Histology Type and Age at Diagnosis: A Joint Study from Five Nordic Countries. Eur Urol 2015; 68(2):283-9.

Frank C, Fallah M, Sundquist J, Hemminki A, Hemminki K. Population Landscape of Familial Cancer. Sci Rep 2015; 5:12891.

Chen T, Fallah M, Jansen L, Castro FA, Krilaviciute A, Katalinic A, Emrich K, Holleczek B, Geiss K, Eberle A, Sundquist J, Brenner H, Hemminki H, for the GEKID Cancer Survival Working Group. Distribution and risk of the second discordant primary cancers combined after a specific first primary cancer in German and Swedish cancer registries. Cancer Letters 2015; 369:152-166.

Brenner H. Colorectal cancer screening for older adults. BMJ 2015; 350:h2029.

Schöttker B, Brenner H. Vitamin D as a resilience factor, helpful for survival of potentially fatal conditions. A hypothesis emerging from recent findings of the ESTHER cohort study and the CHANCES consortium. Nutrients 2015; 7:3264-3278.

Sobral-Leite M, Wesseling J, Smit V, Nevanlinna H, van Miltenburg MH, ..., Brenner H, Butterbach K, Arndt V, Holleczek B, ..., García-Closas M, de Graauw M, Schmidt MK. Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis. BMC Medicine 2015; 13:156.

Darabi H, McCue K, Beesley J, Michailidou K, ..., Brenner H, ..., Arndt V, ..., Dunning AM, Easton DF, Hall P, Cevenix-Trench G. Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate NRBF2 expression. American Journal of Human Genetics 2015; 97:22-34.

Thrift AP, Gong J, Peters U, Chang-Claude J, Rudolph A, Slattery ML, Chan AT, Locke AE, Kahali B, Justice AE, Pers TH, Gallinger S, Hayes RB, Baron JA, Caan BJ, Ogino S, Berndt SI, Chanock SJ, Casey G, Haile RW, Du M, Harrison TA, Thornquist M, Duggan DJ, Le Marchand L, Lindor NM, Seminara D, Song M, Wu K, Thibodeau SN, Cotterchio M, Win AK, Jenkins MA, Hopper JL, Ulrich CM, Potter JD, Newcomb PA, Hoffmeister M, Brenner H, White E, Hsu L, Campbell PT. Mendelian randomization study of body mass index and colorectal cancer risk. Cancer Epidemiology, Biomarkers and Prevention 2015; 24:1024-1031.

Schöttker B, Zhang Y, Heiss JA, Butterbach K, Jansen EHJM, Bewerunge-Hudler M, Saum KU, Holleczek B, Brenner H. Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood. Genes Chromosomes and Cancer 2015; 54:583-594.

Gondos A, Krilaviciute A, Smailyte G, Ulys A, Brenner H. Cancer surveillance using registry data: results and recommendations for the Lithuanian national prostate cancer early detection programme. European Journal of Cancer 2015; 51:1630-1637.

Brenner H, Altenhofen L, Kretschmann J, Rösch T, Pox C, Stock C, Hoffmeister M. Trends in adenoma detection rates during the first 10 years of the German screening colonoscopy program. Gastroenterology 2015; 149:356-366.

Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier B, Brenner H. Smoking habits and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort. Experimental Gerontology 2015; 70:18-25.

Szulkin R, Whitington T, Eklund M, Aly M, Eeles RA, ..., Brenner H, Butterbach K, Stegmaier C, ..., the PRACTICAL consortium, Gronberg H, Wiklund F. Prediction of individual genetic risk to prostate cancer using a polygenic score. The Prostate 2015; 75:1467-1474.

Freigofas J, Seidling HM, Quinzler R, Schöttker B, Saum KU, Brenner H, Haefeli WE. Characteristics of medication schedules used by elderly ambulatory patients. European Journal of Clinical Pharmacology 2015; 71:1109-1120.

Childs EJ, Mocci E, Campa D, Bracci PM, Gallinger S, Goggins MG, Li D, Neale R, Olson SH, Scelo G, Bamlet WR, Bijlsma M, Blackford A, Borges M, Brennan P, Brenner H, Bueno-de-Mesquita HB, Canzian F. Capurso G, Cavestro GM, Chaffee KG, Cleary SP, Cotterchio M, Foretova L, Funel N, Gazouli M, Hassan M, Holcatova I, Holly EA, Janout V, Key TJ, Kupcinskas J, Kurtz RC Landi S, Lu L, Malecka-Panas E, Mambrini A, Mohelnikova-Duchonova B, Neoptolemos JP, Oberg AL, Orlow I, Pasquali C, Pezzilli R, Rizzato C, Saldia A, Scarpa A, Strobel O, Tavano F, Vashist YK, Vodicka P, Yu H, Petersen GM, Risch H, Klein AP. Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. Nature Genetics 2015; 47:911-916.

Candido do Reis FJ, Lynn S, Ali HR, Eccles D, Hanby A, Provenzano E, Caldas C, Howqat WJ, McDuffus LA, Liu B, Daley F, Coulson P, Vyas RJ, Harris LM, Owens JM, Carton AFM, McQuillan JP, Paterson AM, Hirji Z, Christie SK, Holmes AR, Schmidt MK, Garcia-Closas M, Easton DF, Bolla MK, Wang Q, Benitez J, Milne RL, Mannermaa A, couch F, Defilee P, cox A, Cross SS, Blows FM, Sanders J, de Groot R, Figueroa J, Sherman M, Hooning M, Brenner H, Holleczek B, Stegmaier C, Lintott C, Pharoah PDP for the Citizen Science Alliance. Croudsourcing the general public for large scale molecular pathology studies in cancer. EBioMedicine 2015; 2:681-689.

Meid AD, Quinzler R, Feigofas J, Saum K-U, Schöttker B, Holleczek B, Heider D, König H-H, Brenner H, Haefeli WE. Medication underuse in aging outpatients with cardiovascular disease: prevalence, determinants, and outcomes in a prospective cohort study. PLoS One 2015;10:e0136339.

Surinova S, Choi M, Tao S, Schüffler PJ, Chang CY, Clough T, Vyslouzil K, Khoylou M, Srovnal J, Liu Y, Matondo M, Hüttenhain R, Weisser H, Buhmann JM, Hajdúch M, Brenner H, Vitek O, Aebersold R. Prediction of colorectal cancer diagnosis based on circulating plasma proteins. EMBO Molecular Medicine 2015; 7:1166-1178.

Surinova S, Radová L, Choi M, Srovnal J, Brenner H, Vitek O, Hajdúch M,  Aebersold R. Non-invasive prognostic protein biomarker signatures associated with colorectal cancer. EMBO Molecular Medicine 2015; 7:1153-1165.

Khalili H, Gong J, Brenner H, Austin TR, Hutter CM, Baba Y, Baron JA, Berndt SI, Bézieau S, Caan B, Campbell PT, Chang-Claude J, Chanock SJ, Chen C, Hus L, Jiao S, Conti DV, Duggan D, Fuchs CS, Gala M, Gallinger S, Haile RW, Harrison TA, Hayes R, Hazra A, Henderson B, Haiman C, Hoffmeister M, Hopper JL, Jenkins MA, Kolonel LN, Küry S, LaCroix A, le Marchand L, Lemire M, Lindor NM, Ma J, Manson JE, Morikawa T, nan H, Ng K, Newcomb PA, Nishihara R, Potter JD, Qu C, Schoen RE, Schumacher FR, Seminara D, Taverna D, Thibodeau S, Wactawski-Wende J, White E, Wu K, Zanke BW, Casey G, Hudson TJ, Kraft P, Peters U, Slattery ML, Ogino S, Chan AT on behalf of GECCO and CCFR. Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carciogenesis 2015; 36:999-1007.

Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kin C, Lutz S, Rosenberger A, Aben KK, Andrew AS, Breslau N, Chang SC, Dieffenbach AK, Dienemann H, Frederiksen B, Han J, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Heinrich H, Hokanson JE, Hunter DJ, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare D, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Kraft P, Amos CI, Bierut LJ. CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis - a meta-analysis. Journal of the National Cancer Institute 2015; 107:djv100.

Rothenbacher D, Dallmeier D, Mons U, Rosamond W, Koenig W, Brenner H. Sexual activity patterns before myocardial infarction and risk for subsequent cardiovascular adverse events. JACC 2015; 66:1516-1517.

Brenner H. Mortality from malignant melanoma in an era of nationwide skin cancer screening. Deutsches Ärzteblatt 2015; 112:627-628.

Anderson LA, Tavilla A, Brenner H, Luttmann S, Navaro C, Gavin AT, Holleczek B, Johnston BT, Cook MB, Bannon f, Sant M, EUROCARE-5 Working Group. Survival for oesophageal, stomach and small intestine cancers: results from EUROCARE-5. European Journal of Cancer 2015; 51:2144-2157.

Holleczek B, Rossi S, Domenic A, Innos K, Minicozzi P, Francisci S, Hackl M, Eisemann N, Brenner H, and the EUROCARE-5 Working Group. On-going improvement and persistent differences in the survival for patients with colon and rectum cancer across Europe - results from the EUROCARE-5 study. European Journal of Cancer 2015; 51:2158-2168.

Gao X, Jia M, Zhang Y, Breitling LP, Brenner H. DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies. Clinical Epigenetics 2015; 7:113.

Brenner H, Stock C, Hoffmeister M. Colorectal cancer screening: the time to act is now. BMC Medicine 2015; 13:262.

Bozorgmehr K, Maier W, Brenner H, Saum KU, Stock C, Miksch A, Holleczek B, Szecsenyi J, Razum O. Social disparities in Disease Management Programmes for coronary heart disease in Germany: A cross-classified multilevel analysis. Journal of Epidemiology & Community Health 2015; 69:1091-1101.

Galeone C, Turati F, Zhang ZF, Guerico V, Tavani A, Serraino D, Brennan P, Fabianova E, Lissowska J, Mates D, Rudnai P, Shangina O, Szeszenia-Dabrowska N, Vaughan TL, Kelsey K, McClean M, Levi F, Hayes RB, Purdue MP, Bosetti C, Brenner H, Pelucchi C, Lee YCA, Hashibe M, Boffetta P, La Vecchia C. Relation of allium vegetables intake with head and neck cancers: evidence from the INHANCE Consortium. Molecular Nutrition and Food Research 2015; 59:1641-1650.

Castro FA, Jansen L, Krilaviciute A, Katalinic A, Pulte D, Sirri E, Ressing M, Holleczek B, Luttmann S, Brenner H, for the GEKID Cancer Survival Working Group. Survival of patients with gastric lymphoma in Germany and the United States. Journal of Gastroenterology and Hepatology 2015; 30:1485-1491.

Perna L, Mons U, Rujescu D, Kliegel M, Brenner H. Apolipoprotein E e4 and cognitive function: a modifiable association? Results from two independent cohort studies. Dementia and Geriatric Cognitive Disorders 2015; 41:35-45.

Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, ..., Arndt V, ..., Brenner H, ..., Murabito JM, Perry JRB, Murray A. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics 2015; 47:1294-1303.

Imhof A, Koenig W, Jaensch A, Mons U, Brenner H, Rothenbacher D. Long-term prognostic value of lgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease. Atherosclerosis 2015; 243:414-420.

Lemire M, Qu C, Loo LWM, Zaidi SHE, Wang H, Berndt SI, Bézieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Du M, Edlund CK, Gallinger S, Haile RW, Harrision TA, Hoffmeister M, Hopper JL, Hou L, Hsu L, Jacobs EJ, Jenkins MA, Jeon J, Küry S, Li L, Lindor NM, Newcomb PA, Potter JD, Rennert G, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Severi G, Slattery ML, White E, Wood MO, Cotterchio M, Le Marchand L, Casey G, Gruber SB, Peters U, Hudson TJ. A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1. Human Genetics 2015; 134:1249-1262.

Guo X, Long J, Zeng C, Michailidou K, Ghoussaini M, ..., Arndt V, ..., Brenner H, ..., Dunning AM, Easton DF, Zheng W. Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk. Cancer Epidemiology, Biomarkers & Prevention 2015; 24:1680-1691.

Brenner H, Altenhofen L, Stock C, Hoffmeister M. Vorsorge-Koloskopie in Deutschland - Bilanz und Perspektiven. Endoskopie heute 2015; 28:174-177.

Krilaviciute A, Heiss JA, Leja M, Kupcinskas J, Haick H, Brenner H. Detection of cancer through exhaled breath: a systematic review. Oncotarget 2015; 6:38643-38657.

Pfütze K, Benner A, Hoffmeister M, Jansen L, Yang R, Bläker H, Herpel E, Ulrich A, Ulrich CM, Chang-Claude J, Brenner H, Burwinkel B. Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy. Genomics 2015; 106:348-354.

Eberle A, Jansen L, Krilaviciute A, Luttmann S, Emrich K, Holleczek B, Nennecke A, Katalinic A, Brenner H, for the GEKID Cancer Survival Working Group. Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients. Lung Cancer 2015; 90(3):528-533.

Haug U, Rösch T, Hoffmeister M, Katalinic A, Brenner H, Becker N. Einführung eines organisierten Darmkrebs-Screenings in Deuschland: Chancen und Herausforderungen. Das Gesundheitswesen 2015; 77(11):869-74.
 

2014

Zeller G, Tap J, Voigt AY, Sunagawa S, Kultima JR, Costea PI, Amiot A, Böhm J, Brunetti F, Habermann N, Hercog R, Koch M, Luciani A, Mende DR, Schneider MA, Schrotz-King P, Tournigand C, Tran Van Nhieu J, Yamada T, Zimmermann J, Benes V, Kloor M, Ulrich CM, von Knebel Doeberitz M, Sobhani I, Bork P. (2014), "Potential of fecal microbiota for early-stage detection of colorectal cancer". Mol Syst Biol, 2014. 10(11): p. 766.

Liesenfeld DB, Habermann N, Toth R, Owen RW, Frei E, Böhm J, Schrotz-King P, Klika KD, Ulrich CM (2014), "Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare)". Metabolomics, 2014, Vol. 10, Nr. 6. DOI 10.1007/s11306-014-0758-3

Ristau J, Staffa J, Schrotz-King P, Gigic B, Makar KW, Hoffmeister M, Brenner H, Ulrich A, Schneider M, Ulrich CM, Habermann N. (2014), "Suitability of Circulating miRNAs as Potential Prognostic Markers in Colorectal Cancer". Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12): 2632-7. PMID: 25472670

Schmid D, Steindorf K, Leitzmann MF (2014): Epidemiologic Studies of Physical Activity and Primary Prevention of Cancer. Dt. Zeitschrift für Sportmedizin, 65, 5-10.

Klassen O, Schmidt ME, Scharhag-Rosenberger F, Sorkin M, Ulrich CM, Schneeweiss A, Potthoff K, Steindorf K*, Wiskemann J* (2014): Cardiorespiratory fitness in breast cancer patients undergoing adjuvant therapy. Acta Oncologica, 53, 1356-65. *Shared last authorship

Wiskemann J, Steindorf K (2014): Resistance training as supportive therapy in Oncology [in German]. Dt. Zeitschrift für Sportmedizin, 65, 22-24.

Wientzek A, Vigl M, Steindorf K, Brühmann B, Bergmann MM, Harttig U, Katzke V, Kaaks R, Boeing H (2014): The Improved Physical Activity Index for measuring physical activity in EPIC Germany. PLos One, 9, e92005, epub only.

Steindorf K, Schmidt ME, Wiskemann J, Ulrich CM (2014). Physiologic and molecular mechanisms linking endurance and resistance training with effects for cancer patients. Dt. Zeitschrift für Sportmedizin, 65, 299-303.

Brühmann B, Schmidt ME, Steindorf K (2014): Assessment of physical activity in epidemiological studies: Are questionnaires obsolete in the era of accelerometry? GMS Medizinische Informatik, Biometrie und Epidemiologie, 10(1). doi:10.3205/mibe000155.

Steindorf K*, Schmidt ME*, Klassen O, Ulrich CM, Oelmann J, Habermann N, Beckhove P, Owen R, Debus J, Wiskemann J, Potthoff K (2014): Randomized Controlled Trial of Resistance Training in Breast Cancer Patients Receiving Adjuvant Radiotherapy: Results on Cancer-related Fatigue and Quality of Life. Annals of Oncology, 25, 2237-43. *Shared first authorship

Scharhag-Rosenberger F, Becker T, Streckmann F, Schmidt K, Berling A, Bernardi A, Engeroff T, Exner AK, Gutekunst K, Hofmeister D, Jensen W, Kähnert H, Kneis S, Limbach M, Mau-Möller A, Röcker K, Schmidt ME, Schmidt T, Stöckel T, Wehrle A, Wiskemann J, Zimmer P, Zopf E, Steindorf K (2014). Studien zu körperlichem Training bei onkologischen Patienten: Empfehlungen zu den Erhebungsmethoden. Dt. Zeitschrift für Sportmedizin, 65, 304-313.

Steindorf K, Schmidt ME, Scharhag-Rosenberger F, Wiskemann J (2014): Supportive Sport- und Bewegungstherapie für onkologische Patienten. Onkologie Heute, 9, 41-46.

Schmidt ME, Wiskemann J, Steindorf K (2014). Exercise in breast cancer patients: impact on health. Breast Cancer Management 3:241–250.

Kuehl R, Scharhag-Rosenberger F, Schommer K, Dreger P, Bohus M, Wiskemann J (2014). Exercise intensity classification in cancer patients undergoing allogeneic HSCT. Medicine & Science in Sport and Exercise; epub ahead of print

Wiskemann J, Scharhag-Rosenberger F (2014). Nebenwirkungsorientierte Behandlungspfade für die bewegungstherapeutische Betreuung onkologischer Patienten. Bewegungstherapie und Gesundheitssport 30(4), 146-150

Huebner J, Marienfeld S, Abbenhardt C, Ulrich CM, Muenstedt K, Micke O, Muecke R., Loeser C. Counseling patients on cancer diets: a review of the literature and recommendations for clinical practice. Anticancer Research 2014;34,39-48.

Stiborová M, Frei E. Ellipticines as DNA-targeted chemotherapeutics, Current Med. Chem. 2014;21,575-591.

Wiskemann J, Steindorf K (2014). Standards der Sportmedizin: Krafttraining als Supportivtherapie bei onkologischen Patienten [Resistance training as supportive therapy for cancer patients]. Deutsche Zeitschrift für Sportmedizin, 65(1): 22-24.

Klassen O, Schmidt ME, Scharhag-Rosenberger F, Sorkin M, Ulrich CM, Schneeweiss A, Potthoff K, Steindorf K*, Wiskemann J* (2014): Cardiorespiratory fitness in breast cancer patients undergoing adjuvant therapy. Acta Oncologica, 53, 1356-65. *Shared last authorship

Wientzek A, Vigl M, Steindorf K, Brühmann B, Bergmann MM, Harttig U, Katzke V, Kaaks R, Boeing H (2014): The Improved Physical Activity Index for measuring physical activity in EPIC Germany. PLos One, 9, e92005.

Steindorf K*, Schmidt ME*, Klassen O, Ulrich CM, Oelmann J, Habermann N, Beckhove P, Owen R, Debus J, Wiskemann J, Potthoff K (2014): Randomized Controlled Trial of Resistance Training in Breast Cancer Patients Receiving Adjuvant Radiotherapy: Results on Cancer-related Fatigue and Quality of Life. Annals of Oncology, 25, 2237-43. *Shared first authorship

Brühmann, BA, Schmidt, ME, Wientzek A, Vigl M, Teucher B, Katzke VA, Boeing H, Bergmann MM, Kaaks R, Steindorf K (2014): Reliability and validity of the Questionnaire on Annual Physical Activity Pattern: A validation study using combined heart rate and accelerometry data as an objective measurement. World Journal of Epidemiology and Cancer Prevention, 3, 51-63.

Bücher

  1. Baumann FT, Wiskemann J (2014). Sport- und Bewegungstherapie. In: Heim R, Weis J eds. Fatigue bei Krebserkrankungen, 154-165. Stuttgart: Schattauer Verlag.
  2. Baumann F, Schüle K, Leitzmann M, Steindorf K (2015): Präventionsbroschüre „Schritt für Schritt zur Bewegung“. Herausgeber Deutsche Krebshilfe und Deutsche Krebsgesellschaft, Bonn/Berlin. 74 Seiten.

Sonstige Schriften

  1. Löser C, Arends J, , Steindorf K, Scheppach W, Staffa J, Ulrich CM, Wiskemann J, Riemann JF (2014). Prävention und Therapie von Dickdarmkrebs – Plädoyer für einen gesunden Lebensstil - Frankfurter Erklärung der Stiftung Lebensblicke.

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