Functional Genome Analysis (B070)
Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580
D-69120 Heidelberg, Germany.
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Archive
Overview
DNA-Microarray Technologies
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Technical advances in production
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MolTools
project
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Transcription factor binding
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Peptide Nucleic Acid (PNA)
Genome Mapping & Sequencing
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directed gap closure (RDA)
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microbial genomes
Transcriptional Profiling
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microRNA functions
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Blood-based microRNA diagnostics
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mRNA studies
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Cancer
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Yeast
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Arabidopsis
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Drosophila
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Trypanosoma
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Microbes
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Data repository
Epigenetics
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Common cancer biomarker
GHSR
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microRNA-192 promoter in PDAC
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Correction of experimental biases
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Epigenetically regulated miR-375
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NGFN epigenetics platform
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Carcinoma drug resistance
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Initial profiling
Tumour Analyses
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PDAC: tumour environment
communication
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PDAC: peritumoral tissue
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Melanoma: immune response markers
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Melanoma: tumour niche formation
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Melanome: avoiding immune escape
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PDAC: reason for early cancer
progression
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Genome-wide shRNA screens
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Breast:
SALL1
acts as tumour supressor
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Breast: genes promoting stem cell form.
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PDAC: sensitisation to gemcitabine
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PDAC: PaCaNet consortium
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PDAC: susceptibility loci
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PDAC:
K-RA
S &
CDKN2A
mutations
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PDAC: drug & compound effects
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Breast: epigenetically regulated miR-375
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PDAC:
MolDiagPaCa
consortium
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RDA-based cancer gene detection
Proteomics - Antibody Mcroarrays
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Selection of specific antibodies
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Affinomics
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Gastric cancer
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Bladder cancer recurrence
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Glioblastoma
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Plasma-based lymphoma diagnosis
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ARTAMIS
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Pancreatic cancer cell proteome
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AffinityProteome
&
ProteomeBinders
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Protein extraction procedure
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Single-molecule detection
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Protein labelling strategies
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Kinetics & mass transport
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Production parameters
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Computational Proteomics Subgroup
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Overview
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