Research Program E: Imaging and Radiooncology

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Below you will find DKFZ divisions and research groups of the Research Program Imaging and Radiooncology who are interested in recruiting Postdocs within the 2018 DKFZ Postdoctoral Fellowships Selection.

Please note that this is not an exhaustive list and new groups are continously added.

You may also contact the principal investigator of the DKFZ research group of your choice directly to discuss about current possibilities. More information about hiring labs can be found below and descriptions of DKFZ research programs via the general topic locator.

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Medical Physics in Radiology – Prof. Dr. Mark Ladd

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RESEARCH PROFILE

The Division of Medical Physics in Radiology plays a pivotal role in developing new and optimizing existing methods for all imaging-based diagnostic and therapeutic procedures. We are working on new methodology for magnetic resonance imaging (MRI), positron emission tomography (PET), and optical imaging. We are also developing new targeted contrast agents that enable the monitoring of molecular processes in vivo. We are working on projects involving new image acquisition or reconstruction methodologies, and we develop innovative hardware components and perform numerical simulations to optimize designs and ensure safe use.

 

Please visit our website for further information on our research and recent publications.

LINK: http://www.dkfz.de/en/medphysrad

Medical Image Computing – PD Dr. Klaus Maier-Hein

RESEARCH PROFILE

The division of Medical Image Computing focuses on machine learning, especially in the context of big data applications where large-scale heterogeneous data sources are analyzed. Deep learning techniques that explicitly deal with uncertainty in the data or that solve problems "end-to-end" are of particular interest to us. We also pursue novel image computing concepts that combine mathematical modelling approaches with current machine learning technology. The division further encompasses two dedicated groups focusing on and translation of the developed techniques into clinical practice. In this context we contribute to several consortia such as the German Cancer Consortium (DKTK) or the National Center for Tumor Diseases (NCT).

Link: https://www.dkfz.de/en/mic

Biomedical Physics in Radiation Oncology – Prof. Dr. Joao Seco

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RESEARCH PROFILE

Radiotherapy (RT) is one of the main approaches for cancer treatment used alone or in combination with chemotherapy. Different types of radiation sources are currently used, such as photons (X-rays) and heavy charged particles (protons and carbon ions (12C)). Radiation enables to kill proliferating cancer cells, while limiting the effects on healthy tissues. The main cellular target of ionizing radiation is the nuclear DNA. In general, RT works by causing cellular genomic damages, either directly by interacting and injuring DNA, or indirectly, by ionizing water molecules. In this last effect, radiation induces the formation of Reactive Oxygen Species (ROS), such as superoxide anion (•O-2), singlet oxygen (1O2), hydrogen peroxide (H2O2) and the extremely reactive hydroxyl radical (•OH), that may alter DNA and protein structure, as well as lead to lipid peroxidation.

My Current Research interest is to investigate the mechanism of radiation triggered DNA damage via reactive oxygen species (ROS).

Please visit our website for further information on our research and recent publications.

Link: https://www.dkfz.de/en/medizinische-physik-radioonkologie/index.php

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