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Research

Publications of Pediatric Neurooncology

2021

Kolb, T. (First author) ; Khalid, U. ; Simovi?, M. ; Ratnaparkhe, M. ; Wong, J. ; Jauch, A. ; Schmezer, P. ; Rode, A. ; Sebban, S. ; Haag, D. ; Hergt, M. ; Devens, F. ; Buganim, Y. ; Zapatka, M. ; Lichter, P. ; Ernst, A. (Last author)
A versatile system to introduce clusters of genomic double-strand breaks in large cell populations.
Genes, chromosomes & cancer 60(5), 303-313 (2021) [10.1002/gcc.22890]2021 BibTeX | EndNote: XML, Text | RIS

Ecker, J. (First author) ; Thatikonda, V. ; Sigismondo, G. ; Selt, F. ; Valinciute, G. ; Oehme, I. ; Müller, C. ; Buhl, J. L. ; Ridinger, J. ; Usta, D. ; Qin, N. ; van Tilburg, C. M. ; Herold-Mende, C. ; Remke, M. ; Sahm, F. ; Westermann, F. ; Kool, M. ; Wechsler-Reya, R. J. ; Chavez, L. ; Krijgsveld, J. ; Jäger, N. ; Pfister, S. M. ; Witt, O. ; Milde, T. (Last author)
Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.
Neuro-Oncology 23(2), 226-239 (2021) [10.1093/neuonc/noaa191]2021 BibTeX | EndNote: XML, Text | RIS

Miele, E. ; Po, A. ; Mastronuzzi, A. ; Carai, A. ; Besharat, Z. M. ; Pediconi, N. ; Abballe, L. ; Catanzaro, G. ; Sabato, C. ; De Smaele, E. ; Canettieri, G. ; Di Marcotullio, L. ; Vacca, A. ; Mai, A. ; Levrero, M. ; Pfister, S. M. ; Kool, M. ; Giangaspero, F. ; Locatelli, F. ; Ferretti, E.
Downregulation of miR-326 and its host gene ?-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth.
Molecular oncology 15(2), 523-542 (2021) [10.1002/1878-0261.12800.]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Massimino, M. ; Barretta, F. ; Modena, P. ; Witt, H. ; Minasi, S. ; Pfister, S. M. ; Pajtler, K. W. ; Antonelli, M. ; Gandola, L. ; Garrè, M. L. ; Bertin, D. ; Mastronuzzi, A. ; Mascarin, M. ; Quaglietta, L. ; Viscardi, E. ; Sardi, I. ; Ruggiero, A. ; Pollo, B. ; Buccoliero, A. ; Boschetti, L. ; Schiavello, E. ; Chiapparini, L. ; Erbetta, A. ; Morra, I. ; Gessi, M. ; Donofrio, V. ; Patriarca, C. ; Giangaspero, F. ; Johann, P. ; Buttarelli, F. R.
The AIEOP 2nd series of children and adolescents intracranial Ependymoma. An integrated molecular and clinical characterization with a long-term follow-up.
Neuro-Oncology 23(5), 848-857 (2021) [10.1093/neuonc/noaa257]2021 BibTeX | EndNote: XML, Text | RIS

Dejaegher, J. ; Solie, L. ; Hunin, Z. ; Sciot, R. ; Capper, D. ; Siewert, C. ; Van Cauter, S. ; Wilms, G. ; van Loon, J. ; Ectors, N. ; Fieuws, S. ; Pfister, S. ; Van Gool, S. W. ; De Vleeschouwer, S.
DNA Methylation based glioblastoma subclassification is related to tumoral T cell infiltration and patient survival.
Neuro-Oncology 23(2), 240-250 (2021) [10.1093/neuonc/noaa247]2021 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Sill, M. ; Schrimpf, D. ; Stichel, D. ; Reuß, D. ; Sturm, D. ; Hench, J. ; Frank, S. ; Krskova, L. ; Vicha, A. ; Zapotocky, M. ; Bison, B. ; Castel, D. ; Grill, J. ; Debily, M.-A. ; Harter, P. N. ; Snuderl, M. ; Kramm, C. M. ; Reifenberger, G. ; Korshunov, A. ; Jabado, N. ; Wesseling, P. ; Wick, W. ; Solomon, D. A. ; Perry, A. ; Jacques, T. S. ; Jones, C. ; Witt, O. ; Pfister, S. ; von Deimling, A. ; Jones, D. (Last author) ; Sahm, F. (Last author)
A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.
Neuro-Oncology 23(1), 34-43 (2021) [10.1093/neuonc/noaa251]2021 BibTeX | EndNote: XML, Text | RIS

Albert, T. K. ; Interlandi, M. ; Sill, M. ; Graf, M. ; Moreno, N. ; Menck, K. ; Rohlmann, A. ; Melcher, V. ; Korbanka, S. ; Meyer zu Hörste, G. ; Lautwein, T. ; Frühwald, M. C. ; Krebs, C. F. ; Holdhof, D. ; Schoof, M. ; Missler, M. ; Bleckmann, A. ; Dugas, M. ; Schüller, U. ; Jäger, N. ; Pfister, S. ; Kerl, K.
An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma
Neuro-Oncology 23(4), 586?598 (2021) [10.1093/neuonc/noaa254]2021 BibTeX | EndNote: XML, Text | RIS

Suwala, A. K. (First author) ; Stichel, D. ; Schrimpf, D. ; Kloor, M. ; Wefers, A. K. ; Reinhardt, A. ; Maas, S. L. N. ; Kratz, C. P. ; Schweizer, L. ; Hasselblatt, M. ; Snuderl, M. ; Abedalthagafi, M. S. J. ; Abdullaev, Z. ; Monoranu, C. M. ; Bergmann, M. ; Pekrun, A. ; Freyschlag, C. ; Aronica, E. ; Kramm, C. M. ; Hinz, F. ; Sievers, P. ; Korshunov, A. ; Kool, M. ; Pfister, S. M. ; Sturm, D. ; Jones, D. T. W. ; Wick, W. ; Unterberg, A. ; Hartmann, C. ; Dodgshun, A. ; Tabori, U. ; Wesseling, P. ; Sahm, F. ; von Deimling, A. ; Reuß, D. (Last author)
Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
Acta neuropathologica 141(1), 85-100 (2021) [10.1007/s00401-020-02243-6]2021 BibTeX | EndNote: XML, Text | RIS

Bale, T. A. ; Sait, S. F. ; Benhamida, J. ; Ptashkin, R. ; Haque, S. ; Villafania, L. ; Sill, M. ; Sadowska, J. ; Akhtar, R. B. ; Liechty, B. ; Juthani, R. ; Ladanyi, M. ; Fowkes, M. ; Karajannis, M. A. ; Rosenblum, M. K.
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).
Acta neuropathologica 141(1), 123-125 (2021) [10.1007/s00401-020-02245-4]2021 BibTeX | EndNote: XML, Text | RIS

Thomas, C. ; Soschinski, P. ; Zwaig, M. ; Oikonomopoulos, S. ; Okonechnikov, K. ; Pajtler, K. ; Sill, M. ; Schweizer, L. ; Koch, A. ; Neumann, J. ; Schüller, U. ; Sahm, F. ; Rauschenbach, L. ; Keyvani, K. ; Proescholdt, M. ; Riemenschneider, M. J. ; Segewiß, J. ; Ruckert, C. ; Grauer, O. ; Monoranu, C.-M. ; Lamszus, K. ; Patrizi, A. ; Kordes, U. ; Siebert, R. ; Kool, M. ; Ragoussis, J. ; Foulkes, W. D. ; Paulus, W. ; Rivera, B. ; Hasselblatt, M.
The genetic landscape of choroid plexus tumors in children and adults.
Neuro-Oncology 23(4), 650-660 (2021) [10.1093/neuonc/noaa267]2021 BibTeX | EndNote: XML, Text | RIS

Prakash, H. ; Upadhyay, D. ; Bandapalli, O. R. ; Jain, A. ; Kleuser, B.
Host sphingolipids: Perspective immune adjuvant for controlling SARS-CoV-2 infection for managing COVID-19 disease.
Prostaglandins & other lipid mediators 152, 106504 (2021) [10.1016/j.prostaglandins.2020.106504]2021 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Gartlgruber, M. (First author) ; Sharma, A. K. ; Quintero, A. ; Dreidax, D. ; Jansky, S. ; Park, Y.-G. ; Kreth, S. ; Meder, J. ; Doncevic, D. ; Saary, P. ; Toprak, U. H. ; Ishaque, N. ; Afanasyeva, E. ; Wecht, E. ; Koster, J. ; Versteeg, R. ; Grünewald, T. ; Jones, D. T. W. ; Pfister, S. M. ; Henrich, K.-O. ; van Nes, J. ; Herrmann, C. ; Westermann, F. (Last author)
Super enhancers define regulatory subtypes and cell identity in neuroblastoma
Nature cancer 2, 114?128 (2021) [10.1038/s43018-020-00145-w]2021 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Sill, M. (First author) ; Blume, C. ; Tauziede-Espariat, A. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Dogan, H. ; Hartmann, C. ; Mawrin, C. ; Hasselblatt, M. ; Stummer, W. ; Schick, U. ; Hench, J. ; Frank, S. ; Ketter, R. ; Schweizer, L. ; Schittenhelm, J. ; Puget, S. ; Brandner, S. ; Jaunmuktane, Z. ; Küsters, B. ; Abdullaev, Z. ; Pekmezci, M. ; Snuderl, M. ; Ratliff, M. ; Herold-Mende, C. ; Unterberg, A. ; Aldape, K. ; Ellison, D. W. ; Wesseling, P. ; Reifenberger, G. ; Wick, W. ; Perry, A. ; Varlet, P. ; Pfister, S. M. ; Jones, D. T. W. ; von Deimling, A. ; Sahm, F. (Last author)
Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1
Acta neuropathologica 141(2), 281-290 (2021) [10.1007/s00401-020-02247-2]2021 BibTeX | EndNote: XML, Text | RIS

Stichel, D. (First author) ; Schrimpf, D. ; Sievers, P. ; Reinhardt, A. ; Suwala, A. K. ; Sill, M. ; Reuss, D. E. ; Korshunov, A. ; Casalini, B. M. ; Sommerkamp, A. C. ; Ecker, J. ; Selt, F. ; Sturm, D. ; Gnekow, A. ; Koch, A. ; Simon, M. ; Hernáiz Driever, P. ; Schüller, U. ; Capper, D. ; van Tilburg, C. M. ; Witt, O. ; Milde, T. ; Pfister, S. M. ; Jones, D. T. W. ; von Deimling, A. ; Sahm, F. ; Wefers, A. (Last author)
Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data.
Neuropathology & applied neurobiology 47(3), 406-414 (2021) [10.1111/nan.12683]2021 BibTeX | EndNote: XML, Text | RIS

Holdhof, D. ; Johann, P. D. ; Spohn, M. ; Bockmayr, M. ; Safaei, S. ; Joshi, P. ; Masliah-Planchon, J. ; Ho, B. ; Andrianteranagna, M. ; Bourdeaut, F. ; Huang, A. ; Kool, M. ; Upadhyaya, S. A. ; Bendel, A. E. ; Indenbirken, D. ; Foulkes, W. D. ; Bush, J. W. ; Creytens, D. ; Kordes, U. ; Frühwald, M. C. ; Hasselblatt, M. ; Schüller, U.
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases.
Acta neuropathologica 142(2), 291-301 (2021) [10.1007/s00401-020-02250-7]2021 BibTeX | EndNote: XML, Text | RIS

Adolph, J. E. ; Fleischhack, G. ; Mikasch, R. ; Zeller, J. ; Warmuth-Metz, M. ; Bison, B. ; Mynarek, M. ; Rutkowski, S. ; Schüller, U. ; von Hoff, K. ; Obrecht, D. ; Pietsch, T. ; Pfister, S. M. ; Pajtler, K. W. ; Witt, O. ; Witt, H. ; Kortmann, R.-D. ; Timmermann, B. ; Krauß, J. ; Frühwald, M. C. ; Faldum, A. ; Kwiecien, R. ; Bode, U. ; Tippelt, S. ; HIT-Network, G. G. (Collaboration Author)
Local and Systemic Therapy of Recurrent Ependymoma in Children and Adolescents: Short- and Long-term Results of the E-HIT-REZ 2005 Study.
Neuro-Oncology 23(6), 1012-1023 (2021) [10.1093/neuonc/noaa276]2021 BibTeX | EndNote: XML, Text | RIS

Garcia-Moure, M. ; Gonzalez-Huarriz, M. ; Labiano, S. ; Guruceaga, E. ; Bandres, E. ; Zalacain, M. ; Marrodan, L. ; de Andrea, C. E. ; Villalba Esparza, M. ; Martínez-Vélez, N. ; Laspidea, V. ; Puigdelloses, M. ; Gallego Perez-Larraya, J. ; Iñigo-Marco, I. ; Stripecke, R. ; Chan, J. A. ; Raabe, E. H. ; Kool, M. ; Gomez-Manzano, C. ; Fueyo, J. ; Patiño-García, A. ; Alonso, M. M.
Delta-24-RGD, an oncolytic adenovirus, increases survival and promotes proinflammatory immune landscape remodeling in models of AT/RT and CNS-PNET.
Clinical cancer research 27(6), 1807-1820 (2021) [10.1158/1078-0432.CCR-20-3313]2021 BibTeX | EndNote: XML, Text | RIS

Gajjar, A. ; Robinson, G. W. ; Smith, K. S. ; Lin, T. ; Merchant, T. E. ; Chintagumpala, M. ; Mahajan, A. ; Su, J. ; Bouffet, E. ; Bartels, U. ; Schechter, T. ; Hassall, T. ; Robertson, T. ; Nicholls, W. ; Gururangan, S. ; Schroeder, K. ; Sullivan, M. ; Wheeler, G. ; Hansford, J. R. ; Kellie, S. J. ; McCowage, G. ; Cohn, R. ; Fisher, M. J. ; Krasin, M. J. ; Stewart, C. F. ; Broniscer, A. ; Buchhalter, I. ; Tatevossian, R. G. ; Orr, B. A. ; Neale, G. ; Klimo, P. ; Boop, F. ; Srinivasan, A. ; Pfister, S. M. ; Gilbertson, R. J. ; Onar-Thomas, A. ; Ellison, D. W. ; Northcott, P. A.
Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).
Journal of clinical oncology 39(7), 822-835 (2021) [10.1200/JCO.20.01372]2021 BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Sundquist, K. ; Sundquist, J. ; Chen, T. ; Försti, A. ; Hemminki, O. ; Hemminki, K.
Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers
European urology open science 24, 52 - 59 (2021) [10.1016/j.euros.2020.12.007]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Consortium, B. C. A. (Collaboration Author) ; Dorling, L. ; Carvalho, S. ; et al
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.
The New England journal of medicine 384(5), 428-439 (2021) [10.1056/NEJMoa1913948]2021 BibTeX | EndNote: XML, Text | RIS

Kumar, A. (First author) ; Paramasivam, N. ; Bandapalli, O. R. ; Schlesner, M. ; Chen, T. ; Sijmons, R. ; Dymerska, D. ; Golebiewska, K. ; Kuswik, M. ; Lubinski, J. ; Hemminki, K. ; Försti, A. (Last author)
A rare large duplication of MLH1 identified in Lynch syndrome.
Hereditary cancer in clinical practice 19(1), 10 (2021) [10.1186/s13053-021-00167-0]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Endersby, R. ; Whitehouse, J. ; Pribnow, A. ; Kuchibhotla, M. ; Hii, H. ; Carline, B. ; Gande, S. ; Stripay, J. ; Ancliffe, M. ; Howlett, M. ; Schoep, T. ; George, C. ; Andradas, C. ; Dyer, P. ; Schluck, M. ; Patterson, B. ; Tacheva-Gigorova, S. K. ; Cooper, M. N. ; Robinson, G. ; Stewart, C. ; Pfister, S. M. ; Kool, M. ; Milde, T. ; Gajjar, A. ; Johns, T. ; Wechsler-Reya, R. J. ; Roussel, M. F. ; Gottardo, N. G.
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma.
Science translational medicine 13(577), eaba7401 - (2021) [10.1126/scitranslmed.aba7401]2021 BibTeX | EndNote: XML, Text | RIS

Koelsche, C. (First author) ; Schrimpf, D. (First author) ; Stichel, D. (First author) ; et al
Sarcoma classification by DNA methylation profiling.
Nature Communications 12(1), 498 (2021) [10.1038/s41467-020-20603-4]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Kratz, C. P. ; Jongmans, M. C. ; Cavé, H. ; Wimmer, K. ; Behjati, S. ; Guerrini-Rousseau, L. ; Milde, T. ; Pajtler, K. W. ; Golmard, L. ; Gauthier-Villars, M. ; Jewell, R. ; Duncan, C. ; Maher, E. R. ; Brugieres, L. ; Pritchard-Jones, K. ; Bourdeaut, F.
Predisposition to cancer in children and adolescents.
The lancet child & adolescent health 5(2), 142 - 154 (2021) [10.1016/S2352-4642(20)30275-3]2021 BibTeX | EndNote: XML, Text | RIS

Li, X. ; Thomsen, H. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K. (Last author)
Familial Risks between Pernicious Anemia and Other Autoimmune Diseases in the Population of Sweden.
Autoimmune diseases 2021, 8815297 (2021) [10.1155/2021/8815297]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Truong, T. ; Lesueur, F. ; Sugier, P.-E. ; Guibon, J. ; Xhaard, C. ; Karimi, M. ; Kulkarni, O. ; Lucotte, E. A. ; Bacq-Daian, D. ; Boland-Auge, A. ; Mulot, C. ; Laurent-Puig, P. ; Schvartz, C. ; Guizard, A.-V. ; Ren, Y. ; Adjadj, E. ; Rachédi, F. ; Borson-Chazot, F. ; Ortiz, R. M. ; Lence-Anta, J. J. ; Pereda, C. M. ; Comiskey, D. F. ; He, H. ; Liyanarachchi, S. ; de la Chapelle, A. ; Elisei, R. ; Gemignani, F. ; Thomsen, H. ; Forsti, A. ; Herzig, A. F. ; Leutenegger, A.-L. ; Rubino, C. ; Ostroumova, E. ; Kesminiene, A. ; Boutron-Ruault, M.-C. ; Deleuze, J.-F. ; Guénel, P. ; de Vathaire, F.
Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium.
International journal of cancer 148(12), 2935-2946 (2021) [10.1002/ijc.33488]2021 BibTeX | EndNote: XML, Text | RIS

Frühwald, M. C. ; Nemes, K. ; Boztug, H. ; Cornips, M. C. A. ; Evans, D. G. ; Farah, R. ; Glentis, S. ; Jorgensen, M. ; Katsibardi, K. ; Hirsch, S. ; Jahnukainen, K. ; Kventsel, I. ; Kerl, K. ; Kratz, C. P. ; Pajtler, K. W. ; Kordes, U. ; Ridola, V. ; Stutz, E. ; Bourdeaut, F.
Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group.
Familial cancer 20(4), 305-316 (2021) [10.1007/s10689-021-00229-1]2021 BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Okonechnikov, K. ; Schmitt-Hoffner, F. ; Ryzhova, M. ; Sahm, F. ; Stichel, D. ; Schrimpf, D. ; Reuss, D. E. ; Sievers, P. ; Suwala, A. K. ; Kumirova, E. ; Zheludkova, O. ; Golanov, A. ; Jones, D. T. W. ; Pfister, S. M. ; Kool, M. ; von Deimling, A. (Last author)
Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation.
Acta Neuropathologica Communications 9(1), 20 (2021) [10.1186/s40478-021-01118-5]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Haag, D. (First author) ; Mack, N. ; Benites Goncalves da Silva, P. ; Statz, B. ; Clark, J. ; Tanabe, K. ; Sharma, T. ; Jäger, N. ; Jones, D. T. W. ; Kawauchi, D. ; Wernig, M. ; Pfister, S. (Last author)
H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model.
Cancer cell 39(3), 407-422.e13 (2021) [10.1016/j.ccell.2021.01.005]2021 BibTeX | EndNote: XML, Text | RIS

Baroni, L. ; Sundaresan, L. ; Heled, A. ; Coltin, H. ; Pajtler, K. W. ; Lin, T. ; Merchant, T. E. ; McLendon, R. ; Faria, C. ; Buntine, M. ; White, C. L. ; Pfister, S. M. ; Gilbert, M. R. ; Armstrong, T. S. ; Bouffet, E. ; Kumar, S. ; Taylor, M. D. ; Aldape, K. D. ; Ellison, D. W. ; Gottardo, N. G. ; Kool, M. ; Korshunov, A. ; Hansford, J. R. ; Ramaswamy, V.
Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q.
Neuro-Oncology 23(8), 1360-1370 (2021) [10.1093/neuonc/noab034]2021 BibTeX | EndNote: XML, Text | RIS

Fisher, M. J. ; Jones, D. T. W. (First author) ; Li, Y. ; Guo, X. ; Sonawane, P. S. ; Waanders, A. J. ; Phillips, J. J. ; Weiss, W. A. ; Resnick, A. C. ; Gosline, S. ; Banerjee, J. ; Guinney, J. ; Gnekow, A. ; Kandels, D. ; Foreman, N. K. ; Korshunov, A. ; Ryzhova, M. ; Massimi, L. ; Gururangan, S. ; Kieran, M. W. ; Wang, Z. ; Fouladi, M. ; Sato, M. ; Øra, I. ; Holm, S. ; Markham, S. J. ; Beck, P. ; Jäger, N. ; Wittmann, A. ; Sommerkamp, A. C. ; Sahm, F. ; Pfister, S. (Last author) ; Gutmann, D. H.
Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).
Acta neuropathologica 141(4), 605-617 (2021) [10.1007/s00401-021-02276-5.]2021 BibTeX | EndNote: XML, Text | RIS

Catalano, C. (First author) ; Paramasivam, N. ; Blocka, J. ; Giangiobbe, S. ; Huhn, S. ; Schlesner, M. ; Weinhold, N. ; Sijmons, R. ; de Jong, M. ; Langer, C. ; Preuss, K.-D. ; Nilsson, B. ; Durie, B. ; Goldschmidt, H. ; Bandapalli, O. R. ; Hemminki, K. ; Försti, A. (Last author)
Characterization of rare germline variants in familial multiple myeloma.
Blood cancer journal 11(2), 33 (2021) [10.1038/s41408-021-00422-6]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Okonechnikov, K. (First author) ; Stichel, D. ; Ryzhova, M. ; Schrimpf, D. ; Sahm, F. ; Sievers, P. ; Absalyamova, O. ; Zheludkova, O. ; Golanov, A. ; Jones, D. T. W. ; Pfister, S. M. ; von Deimling, A. ; Kool, M. (Last author)
Integrated molecular analysis of adult Sonic Hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.
Neuro-Oncology 23(9), 1576-1585 (2021) [10.1093/neuonc/noab031]2021 BibTeX | EndNote: XML, Text | RIS

Behjati, S. ; Gilbertson, R. J. ; Pfister, S. (Last author)
Maturation Block in Childhood Cancer.
Cancer discovery 11(3), 542-544 (2021) [10.1158/2159-8290.CD-20-0926]2021 BibTeX | EndNote: XML, Text | RIS

Liu, A. P. Y. ; Li, B. K. ; Pfaff, E. ; Gudenas, B. ; Vasiljevic, A. ; Orr, B. A. ; Dufour, C. ; Snuderl, M. ; Karajannis, M. A. ; Rosenblum, M. K. ; Hwang, E. I. ; Ng, H.-K. ; Hansford, J. R. ; Szathmari, A. ; Faure-Conter, C. ; Merchant, T. E. ; Levine, M. ; Bouvier, N. ; von Hoff, K. ; Mynarek, M. ; Rutkowski, S. ; Sahm, F. ; Kool, M. ; Hawkins, C. ; Onar-Thomas, A. ; Robinson, G. W. ; Gajjar, A. ; Pfister, S. M. ; Bouffet, E. ; Northcott, P. A. ; Jones, D. T. W. (Last author) ; Huang, A.
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study.
Acta neuropathologica 141(5), 771-785 (2021) [10.1007/s00401-021-02284-5]2021 BibTeX | EndNote: XML, Text | RIS

Skopelitou, D. (First author) ; Miao, B. ; Srivastava, A. ; Kumar, A. ; Kuswick, M. ; Dymerska, D. ; Paramasivam, N. ; Schlesner, M. ; Lubinski, J. ; Hemminki, K. ; Försti, A. ; Bandapalli, O. R. (Last author)
Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer
International journal of molecular sciences 22(4), 1837 (2021) [10.3390/ijms22041837]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Chan, T. S. Y. ; Picard, D. ; Hawkins, C. E. ; Lu, M. ; Pfister, S. ; Korshunov, A. ; Roussel, M. F. ; Wechsler-Reya, R. J. ; Henkin, J. ; Bouffet, E. ; Huang, A.
Thrombospondin-1 mimetics are promising novel therapeutics for MYC-associated medulloblastoma.
Neuro-oncology advances 3(1), vdab002 (2021) [10.1093/noajnl/vdab002]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hartlieb, S. (First author) ; Sieverling, L. (First author) ; Nadler-Holly, M. ; Ziehm, M. ; Toprak, U. H. ; Herrmann, C. ; Ishaque, N. ; Okonechnikov, K. ; Gartlgruber, M. ; Park, Y.-G. ; Wecht, E. M. ; Savelyeva, L. ; Henrich, K.-O. ; Rosswog, C. ; Fischer, M. ; Hero, B. ; Jones, D. T. W. ; Pfaff, E. ; Witt, O. ; Pfister, S. M. ; Volckmann, R. ; Koster, J. ; Kiesel, K. ; Rippe, K. ; Taschner-Mandl, S. ; Ambros, P. ; Brors, B. ; Selbach, M. ; Feuerbach, L. ; Westermann, F. (Last author)
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Nature Communications 12(1), 1269 (2021) [10.1038/s41467-021-21247-8]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Mannarapu, M. ; Dariya, B. ; Bandapalli, O. R. (Last author)
Application of single-cell sequencing technologies in pancreatic cancer
Molecular and cellular biochemistry 476(6), 2429-2437 (2021) [10.1007/s11010-021-04095-4]2021 BibTeX | EndNote: XML, Text | RIS

Fresnais, M. ; Yildirim, E. ; Karabulut, S. ; Jäger, D. ; Zörnig, I. ; Benzel, J. ; Pajtler, K. W. ; Pfister, S. M. ; Burhenne, J. ; Haefeli, W. E. ; Longuespée, R.
Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives.
Molecules 26(5), 1281 (2021) [10.3390/molecules26051281]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Custers, L. ; Khabirova, E. ; Coorens, T. H. H. ; Oliver, T. R. W. ; Calandrini, C. ; Young, M. D. ; Vieira Braga, F. A. ; Ellis, P. ; Mamanova, L. ; Segers, H. ; Maat, A. ; Kool, M. ; Hoving, E. W. ; van den Heuvel-Eibrink, M. M. ; Nicholson, J. ; Straathof, K. ; Hook, L. ; de Krijger, R. R. ; Trayers, C. ; Allinson, K. ; Behjati, S. ; Drost, J.
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Nature Communications 12(1), 1407 (2021) [10.1038/s41467-021-21675-6]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Niazi, Y. (First author) ; Thomsen, H. ; Smolkova, B. ; Vodickova, L. ; Vodenkova, S. ; Kroupa, M. ; Vymetalkova, V. ; Kazimirova, A. ; Barancokova, M. ; Volkovova, K. ; Staruchova, M. ; Hoffmann, P. ; Nöthen, M. M. ; Dusinska, M. ; Musak, L. ; Vodicka, P. ; Försti, A. ; Hemminki, K. (Last author)
DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population.
DNA repair 101, 103079 (2021) [10.1016/j.dnarep.2021.103079]2021 BibTeX | EndNote: XML, Text | RIS

Srivastava, A. (First author) ; Giangiobbe, S. ; Skopelitou, D. ; Miao, B. ; Paramasivam, N. ; Diquigiovanni, C. ; Bonora, E. ; Hemminki, K. ; Försti, A. ; Bandapalli, O. R. (Last author)
Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer.
Frontiers in endocrinology 12, 600682 (2021) [10.3389/fendo.2021.600682]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Sainz, J. ; García-Verdejo, F. J. ; Martínez-Bueno, M. ; Kumar, A. ; Sánchez-Maldonado, J. M. ; Díez-Villanueva, A. ; Vodi?ková, L. ; Vymetálková, V. ; Martin Sánchez, V. ; Da Silva Filho, M. I. ; Sampaio-Marques, B. ; Brezina, S. ; Butterbach, K. ; ter Horst, R. ; Hoffmeister, M. ; Ludovico, P. ; Jurado, M. ; Li, Y. ; Sánchez-Rovira, P. ; Netea, M. G. ; Gsur, A. ; Vodi?ka, P. ; Moreno, V. ; Hemminki, K. ; Brenner, H. ; Chang-Claude, J. ; Försti, A. (Last author)
Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts
Cancers 13(6), 1258 (2021) [10.3390/cancers13061258]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Thomas, C. ; Federico, A. (First author) ; Sill, M. ; Bens, S. ; Oyen, F. ; Nemes, K. ; Johann, P. D. ; Hartmann, C. ; Hartmann, W. ; Sumerauer, D. ; Paterno, V. ; Samii, A. ; Kordes, U. ; Siebert, R. ; Frühwald, M. C. ; Paulus, W. ; Kool, M. (Last author) ; Hasselblatt, M.
Atypical Teratoid/Rhabdoid Tumor (AT/RT) With Molecular Features of Pleomorphic Xanthoastrocytoma.
The American journal of surgical pathology 45(9), 1228-1234 (2021) [10.1097/PAS.0000000000001694]2021 BibTeX | EndNote: XML, Text | RIS

Upadhyaya, S. A. ; Robinson, G. ; Onar-Thomas, A. ; Orr, B. A. ; Johann, P. ; Wu, G. ; Billups, C. A. ; Tatevossian, R. G. ; Dhanda, S. K. ; Srinivasan, A. ; Broniscer, A. ; Qaddoumi, I. ; Vinitsky, A. ; Armstrong, G. T. ; Bendel, A. ; Hassall, T. E. ; Partap, S. ; Fisher, P. G. ; Crawford, J. R. ; Chintagumpala, M. M. ; Bouffet, E. ; Gururangan, S. ; Mostafavi, R. ; Sanders, R. P. ; Klimo, P. ; Patay, Z. ; Indelicato, D. J. ; Nichols, K. E. ; Boop, F. A. ; Merchant, T. E. ; Kool, M. ; Ellison, D. W. ; Gajjar, A.
Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-Institutional Trials.
Clinical cancer research 27(10), 2879-2889 (2021) [10.1158/1078-0432.CCR-20-4731]2021 BibTeX | EndNote: XML, Text | RIS

Kupp, R. ; Ruff, L. ; Terranova, S. ; Nathan, E. ; Ballereau, S. ; Stark, R. ; Sekhar Reddy Chilamakuri, C. ; Hoffmann, N. ; Wickham-Rahrmann, K. ; Widdess, M. ; Arabzade, A. ; Zhao, Y. ; Varadharajan, S. ; Zheng, T. ; Murugesan, M. K. ; Pfister, S. ; Kawauchi, D. ; Pajtler, K. W. ; Deneen, B. ; Mack, S. C. ; Masih, K. E. ; Gryder, B. E. ; Khan, J. ; Gilbertson, R. J.
ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors.
Cancer discovery 11(9), 2216-2229 (2021) [10.1158/2159-8290.CD-20-1052]2021 BibTeX | EndNote: XML, Text | RIS

Arabzade, A. ; Zhao, Y. ; Varadharajan, S. ; Chen, H.-C. ; Jessa, S. ; Rivas, B. ; Stuckert, A. J. ; Solis, M. ; Kardian, A. ; Tlais, D. ; Golbourn, B. J. ; Stanton, A. J. ; Chan, Y. S. ; Olson, C. ; Karlin, K. L. ; Kong, K. ; Kupp, R. ; Hu, B. ; Injac, S. G. ; Ngo, M. ; Wang, P. R. ; De Leon, L. A. ; Sahm, F. ; Kawauchi, D. ; Pfister, S. ; Lin, C. Y. ; Hodges, H. C. ; Singh, I. ; Westbrook, T. F. ; Chintagumpala, M. M. ; Blaney, S. M. ; Parsons, D. W. ; Pajtler, K. W. ; Agnihotri, S. ; Gilbertson, R. J. ; Yi, J. ; Jabado, N. ; Kleinman, C. L. ; Bertrand, K. C. ; Deneen, B. ; Mack, S. C.
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
Cancer discovery 11(9), 2200-2215 (2021) [10.1158/2159-8290.CD-20-1066]2021 BibTeX | EndNote: XML, Text | RIS

Voronina, N. (First author) ; Aichmüller, C. (First author) ; Kolb, T. (First author) ; Korshunov, A. ; Ryzhova, M. ; Barnholtz-Sloan, J. ; Cioffi, G. ; Sill, M. ; von Deimling, A. ; Pfister, S. M. ; Gronych, J. ; Jones, D. T. W. ; Frisén, J. ; Zapatka, M. ; Ernst, A. (Last author)
The age of adult pilocytic astrocytoma cells.
Oncogene 40(16), 2830-2841 (2021) [10.1038/s41388-021-01738-0]2021 BibTeX | EndNote: XML, Text | RIS

Adachi, T. ; Miyashita, S. ; Yamashita, M. ; Shimoda, M. ; Okonechnikov, K. ; Chavez, L. ; Kool, M. ; Pfister, S. M. ; Inoue, T. ; Kawauchi, D. ; Hoshino, M.
Notch Signaling between Cerebellar Granule Cell Progenitors.
eNeuro 8(3), ENEURO.0468-20.2021 (2021) [10.1523/ENEURO.0468-20.2021]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Deubzer, H. E. ; Eggert, A. ; Pajtler, K. W. (Last author)
Liquid biopsies as a new diagnostic platform in pediatric oncology[?Liquid biopsies? als neue Diagnostikplattform in der pädiatrischen Onkologie]
Der Onkologe 27, 458?463 (2021) [10.1007/s00761-021-00904-z]2021 BibTeX | EndNote: XML, Text | RIS

Pfaff, E. (First author) ; Adam de Beaumais, T. ; Marchais, A. ; van Tilburg, C. M. ; Blattner-Johnson, M. ; Dirksen, U. ; Øra, I. ; Geoerger, B. ; Schleiermacher, G. ; Pfister, S. ; Witt, O. ; Jones, D. T. W. ; Vassal, G.
NTRK Alterations in Pediatric High-Risk Malignancies Identified Through European Clinical Sequencing Programs Constitute Promising Drug Targets
JCO precision oncology 5, 450 - 454 (2021) [10.1200/PO.20.00417]2021 BibTeX | EndNote: XML, Text | RIS

Kommoss, F. K. (First author) ; Stichel, D. ; Mora, J. ; Esteller, M. ; Jones, D. ; Pfister, S. M. ; Brack, E. ; Wachtel, M. ; Bode, P. K. ; Sinn, H.-P. ; Schmidt, D. ; Mentzel, T. ; Kommoss, F. ; Sahm, F. ; von Deimling, A. (Last author) ; Koelsche, C.
Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.
Modern pathology 34(8), 1558-1569 (2021) [10.1038/s41379-021-00804-y]2021 BibTeX | EndNote: XML, Text | RIS

Kumar, R. ; Smith, K. S. ; Deng, M. ; et al
Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma
Journal of clinical oncology 39(7), 807 - 821 (2021) [10.1200/JCO.20.01359]2021 BibTeX | EndNote: XML, Text | RIS

Suwala, A. K. (First author) ; Stichel, D. ; Schrimpf, D. ; Maas, S. L. N. ; Sill, M. ; Dohmen, H. ; Banan, R. ; Reinhardt, A. ; Sievers, P. ; Hinz, F. ; Blattner-Johnson, M. ; Hartmann, C. ; Schweizer, L. ; Boldt, H. B. ; Kristensen, B. W. ; Schittenhelm, J. ; Wood, M. D. ; Chotard, G. ; Bjergvig, R. ; Das, A. ; Tabori, U. ; Hasselblatt, M. ; Korshunov, A. ; Abdullaev, Z. ; Quezado, M. ; Aldape, K. ; Harter, P. ; Snuderl, M. ; Hench, J. ; Frank, S. ; Acker, T. ; Brandner, S. ; Winkler, F. ; Wesseling, P. ; Pfister, S. M. ; Reuss, D. E. ; Wick, W. ; von Deimling, A. ; Jones, D. T. W. ; Sahm, F. (Last author)
Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.
Acta neuropathologica 142(1), 179-189 (2021) [10.1007/s00401-021-02302-6]2021 BibTeX | EndNote: XML, Text | RIS

Zheng, T. (First author) ; Ghasemi, D. R. (First author) ; Okonechnikov, K. (First author) ; Korshunov, A. ; Sill, M. ; Maass, K. K. ; Benites Goncalves da Silva, P. ; Ryzhova, M. ; Gojo, J. ; Stichel, D. ; Arabzade, A. ; Kupp, R. ; Benzel, J. ; Taya, S. ; Adachi, T. ; Shiraishi, R. ; Gerber, N. U. ; Sturm, D. ; Ecker, J. ; Sievers, P. ; Selt, F. ; Chapman, R. ; Haberler, C. ; Figarella-Branger, D. ; Reifenberger, G. ; Fleischhack, G. ; Rutkowski, S. ; Donson, A. M. ; Ramaswamy, V. ; Capper, D. ; Ellison, D. W. ; Herold-Mende, C. C. ; Schuller, U. ; Brandner, S. ; Hernaiz Driever, P. ; Kros, J. M. ; Snuderl, M. ; Milde, T. ; Grundy, R. G. ; Hoshino, M. ; Mack, S. C. ; Gilbertson, R. J. ; Jones, D. T. W. ; Kool, M. ; von Deimling, A. ; Pfister, S. M. ; Sahm, F. (Last author) ; Kawauchi, D. (Last author) ; Pajtler, K. (Last author)
Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas.
Cancer discovery 11(9), 2230-2247 (2021) [10.1158/2159-8290.CD-20-0963]2021 BibTeX | EndNote: XML, Text | RIS

Thomas, C. ; Oehl-Huber, K. ; Bens, S. ; Soschinski, P. ; Koch, A. ; Nemes, K. ; Oyen, F. ; Kordes, U. ; Kool, M. ; Frühwald, M. C. ; Hasselblatt, M. ; Siebert, R.
Transposable element insertion as a mechanism of SMARCB1 inactivation in atypical teratoid/rhabdoid tumor.
Genes, chromosomes & cancer 60(8), 586-590 (2021) [10.1002/gcc.22954]2021 BibTeX | EndNote: XML, Text | RIS

Skopelitou, D. (First author) ; Miao, B. ; Srivastava, A. ; Kumar, A. ; Ku?wik, M. ; Dymerska, D. ; Paramasivam, N. ; Schlesner, M. ; Lubi?ski, J. ; Hemminki, K. ; Försti, A. ; Bandapalli, O. R. (Last author)
A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer.
Journal of Personalized Medicine 11(4), 262 (2021) [10.3390/jpm11040262]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Zin, F. ; Cotter, J. A. ; Haberler, C. ; Dottermusch, M. ; Neumann, J. ; Schüller, U. ; Schweizer, L. ; Thomas, C. ; Nemes, K. ; Johann, P. D. ; Kool, M. ; Frühwald, M. C. ; Paulus, W. ; Judkins, A. ; Hasselblatt, M.
Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup.
Brain pathology 31(5), e12967 (2021) [10.1111/bpa.12967]2021 BibTeX | EndNote: XML, Text | RIS

Lyskjaer, I. ; De Noon, S. ; Tirabosco, R. ; Rocha, A. M. ; Lindsay, D. ; Amary, F. ; Ye, H. ; Schrimpf, D. ; Stichel, D. ; Sill, M. ; Koelsche, C. ; Pillay, N. ; Von Deimling, A. ; Beck, S. ; Flanagan, A. M.
DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'.
The journal of pathology: clinical research 7(4), 350-360 (2021) [10.1002/cjp2.215]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Nasir, A. ; Cardall, A. ; Othman, R. T. ; Nicolaou, N. ; Lourdusamy, A. ; Linke, F. ; Onion, D. ; Ryzhova, M. ; Cameron, H. ; Valente, C. ; Ritchie, A. ; Korshunov, A. ; Pfister, S. M. ; Grabowska, A. M. ; Kerr, I. D. ; Coyle, B.
ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma.
Neuro-oncology advances 3(1), 1-12 (2021) [10.1093/noajnl/vdab030]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Pathak, R. ; Zin, F. ; Thomas, C. ; Bens, S. ; Gayden, T. ; Karamchandani, J. ; Dudley, R. W. ; Nemes, K. ; Johann, P. D. ; Oyen, F. ; Kordes, U. ; Jabado, N. ; Siebert, R. ; Paulus, W. ; Kool, M. ; Frühwald, M. C. ; Albrecht, S. ; Kalpana, G. V. ; Hasselblatt, M.
Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors
Acta neuropathologica 142(2), 361-374 (2021) [10.1007/s00401-021-02328-w]2021 BibTeX | EndNote: XML, Text | RIS

Gao, J.-l. ; Beck, P. (First author) ; Sun, Y.-c. ; Xue, J. ; Wang, G. ; Wang, L.-w. ; Du, Y. ; Zhang, X. ; Sun, J.-g.
Caulobacter endophyticus sp. nov., an endophytic bacterium harboring three lasso peptide biosynthetic gene clusters and producing indoleacetic acid isolated from maize root
Antonie van Leeuwenhoek 114, 1213?1224 (2021) [10.1007/s10482-021-01593-9]2021 BibTeX | EndNote: XML, Text | RIS

Hemminki, K. ; Försti, A. ; Hemminki, A. ; Ljungberg, B. ; Hemminki, O.
Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor.
BMC cancer 21(1), 604 (2021) [10.1186/s12885-021-08371-w]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Simovic, M. (First author) ; Bolkestein, M. ; Moustafa, M. ; Wong, J. K. L. ; Körber, V. ; Benedetto, S. ; Khalid, U. ; Schreiber, H. S. ; Jugold, M. ; Korshunov, A. ; Hübschmann, D. ; Mack, N. ; Brons, S. ; Wei, P.-C. ; Breckwoldt, M. O. ; Heiland, S. ; Bendszus, M. ; Jürgen, D. ; Höfer, T. ; Zapatka, M. ; Kool, M. ; Pfister, S. M. ; Abdollahi, A. ; Ernst, A. (Last author)
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.
Neuro-Oncology 23(12), 2028-2041 (2021) [10.1093/neuonc/noab127]2021 BibTeX | EndNote: XML, Text | RIS

Lötsch, D. ; Kirchhofer, D. ; Englinger, B. ; Jiang, L. ; Okonechnikov, K. ; Senfter, D. ; Laemmerer, A. ; Gabler, L. ; Pirker, C. ; Donson, A. M. ; Bannauer, P. ; Korbel, P. ; Jaunecker, C. N. ; Hübner, J.-M. ; Mayr, L. ; Madlener, S. ; Schmook, M. T. ; Ricken, G. ; Maaß, K. ; Grusch, M. ; Holzmann, K. ; Grasl-Kraupp, B. ; Spiegl-Kreinecker, S. ; Hsu, J. ; Dorfer, C. ; Rössler, K. ; Azizi, A. A. ; Foreman, N. K. ; Peyrl, A. ; Haberler, C. ; Czech, T. ; Slavc, I. ; Filbin, M. G. ; Pajtler, K. W. ; Kool, M. ; Berger, W. ; Gojo, J. (Last author)
Targeting fibroblast growth factor receptors to combat aggressive ependymoma.
Acta neuropathologica 142(2), 339-360 (2021) [10.1007/s00401-021-02327-x]2021 BibTeX | EndNote: XML, Text | RIS

Sauter, M. ; Foerster, K. I. ; Benzel, J. ; Pfister, S. ; Pajtler, K. W. ; Haefeli, W. E. ; Burhenne, J.
Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS.
Journal of chromatography / B 1176, 122781 (2021) [10.1016/j.jchromb.2021.122781]2021 BibTeX | EndNote: XML, Text | RIS

von Hoff, K. ; Haberler, C. ; Schmitt-Hoffner, F. ; et al
Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study
Neuro-Oncology 23(9), 1597-1611 (2021) [10.1093/neuonc/noab136]2021 BibTeX | EndNote: XML, Text | RIS

Schmitt-Hoffner, F. (First author) ; van Rijn, S. ; Toprak, U. H. ; Mauermann, M. ; Rosemann, F. ; Heit-Mondrzyk, A. ; Hübner, J.-M. ; Camgöz, A. ; Hartlieb, S. ; Pfister, S. M. ; Henrich, K.-O. ; Westermann, F. ; Kool, M. (Last author)
FOXR2 Stabilizes MYCN Protein and Identifies Non-MYCN-Amplified Neuroblastoma Patients With Unfavorable Outcome.
Journal of clinical oncology 39(29), 3217-3228 (2021) [10.1200/JCO.20.02540]2021 BibTeX | EndNote: XML, Text | RIS

Vassal, G. ; Houghton, P. J. ; Pfister, S. M. ; Smith, M. A. ; Caron, H. N. ; Li, X.-N. ; Shields, D. J. ; Witt, O. ; Molenaar, J. J. ; Colombetti, S. ; Schuler, J. ; Stancato, L. F.
International consensus on minimum preclinical testing requirements for the development of innovative therapies for children and adolescents with cancer.
Molecular cancer therapeutics 20(8), 1462-1468 (2021) [10.1158/1535-7163.MCT-20-0394]2021 BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, O. ; Hemminki, K.
Bladder and upper urinary tract cancers as first and second primary cancers.
Cancer reports 4(6), e1406 (2021) [10.1002/cnr2.1406]2021 BibTeX | EndNote: XML, Text | RIS

Franceschi, E. ; Seidel, C. ; Sahm, F. ; Pajtler, K. W. ; Hau, P.
How we treat medulloblastoma in adults.
ESMO open 6(4), 100173 (2021) [10.1016/j.esmoop.2021.100173]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K.
Family history of early onset acute lymphoblastic leukemia is suggesting genetic associations.
Scientific reports 11(1), 12370 (2021) [10.1038/s41598-021-90542-7]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Maass, K. (First author) ; Schad, P. (First author) ; Finster, A. (First author) ; Puranachot, P. ; Rosing, F. ; Wedig, T. ; Schwarz, N. ; Stumpf, N. ; Pfister, S. M. ; Pajtler, K. (Last author)
From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube
Cancers 13(12), 3002 (2021) [10.3390/cancers13123002]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hemminki, K. ; Försti, A. ; Hemminki, A. ; Ljungberg, B. ; Hemminki, O.
Progress in survival in renal cell carcinoma through 50 years evaluated in Finland and Sweden.
PLOS ONE 16(6), e0253236 - (2021) [10.1371/journal.pone.0253236]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Ballabio, C. ; Gianesello, M. ; Lago, C. ; Okonechnikov, K. ; Anderle, M. ; Aiello, G. ; Antonica, F. ; Zhang, T. ; Gianno, F. ; Giangaspero, F. ; Hassan, B. A. ; Pfister, S. ; Tiberi, L.
Notch1 switches progenitor competence in inducing medulloblastoma.
Science advances 7(26), eabd2781 - (2021) [10.1126/sciadv.abd2781]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Young, M. D. ; Mitchell, T. J. ; Custers, L. ; Margaritis, T. ; Morales-Rodriguez, F. ; Kwakwa, K. ; Khabirova, E. ; Kildisiute, G. ; Oliver, T. R. W. ; de Krijger, R. R. ; van den Heuvel-Eibrink, M. M. ; Comitani, F. ; Piapi, A. ; Bugallo-Blanco, E. ; Thevanesan, C. ; Burke, C. ; Prigmore, E. ; Ambridge, K. ; Roberts, K. ; Braga, F. A. V. ; Coorens, T. H. H. ; Del Valle, I. ; Wilbrey-Clark, A. ; Mamanova, L. ; Stewart, G. D. ; Gnanapragasam, V. J. ; Rampling, D. ; Sebire, N. ; Coleman, N. ; Hook, L. ; Warren, A. ; Haniffa, M. ; Kool, M. ; Pfister, S. M. ; Achermann, J. C. ; He, X. ; Barker, R. A. ; Shlien, A. ; Bayraktar, O. A. ; Teichmann, S. A. ; Holstege, F. C. ; Meyer, K. B. ; Drost, J. ; Straathof, K. ; Behjati, S.
Single cell derived mRNA signals across human kidney tumors.
Nature Communications 12(1), 3896 (2021) [10.1038/s41467-021-23949-5]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Louis, D. N. ; Perry, A. ; Wesseling, P. ; Brat, D. J. ; Cree, I. A. ; Figarella-Branger, D. ; Hawkins, C. ; Ng, H. K. ; Pfister, S. M. ; Reifenberger, G. ; Soffietti, R. ; von Deimling, A. ; Ellison, D. W.
The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.
Neuro-Oncology 23(8), 1231-1251 (2021) [10.1093/neuonc/noab106]2021 BibTeX | EndNote: XML, Text | RIS

Saunders, C. N. ; Chattopadhyay, S. ; Huhn, S. ; Weinhold, N. ; Hoffmann, P. ; Nöthen, M. M. ; Jöckel, K.-H. ; Schmidt, B. ; Landi, S. ; Goldschmidt, H. ; Milani, P. ; Merlini, G. ; Rowcieno, D. ; Hawkins, P. ; Hegenbart, U. ; Palladini, G. ; Wechalekar, A. ; Schönland, S. O. ; Försti, A. ; Houlston, R. ; Hemminki, K.
Search for AL amyloidosis risk factors using Mendelian randomization.
Blood advances 5(13), 2725 - 2731 (2021) [10.1182/bloodadvances.2021004423]2021 BibTeX | EndNote: XML, Text | RIS

Johann, P. (First author) ; Lenz, D. ; Ries, M.
The drug development pipeline for glioblastoma-A cross sectional assessment of the FDA Orphan Drug Product designation database.
PLOS ONE 16(7), e0252924 - (2021) [10.1371/journal.pone.0252924]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Sundquist, K. ; Sundquist, J. ; Chen, T. ; Försti, A. ; Hemminki, A. ; Hemminki, K. (Last author)
Second Primary Cancers After Gastric Cancer, and Gastric Cancer as Second Primary Cancer.
Clinical epidemiology 13, 515 - 525 (2021) [10.2147/CLEP.S304332]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Glöss, S. ; Jurmeister, P. ; Thieme, A. ; Schmid, S. ; Cai, W. Y. ; Serrette, R. N. ; Perner, S. ; Ribbat-Idel, J. ; Pagenstecher, A. ; Bläker, H. ; Keber, U. ; Stadelmann, C. ; Zechel, S. ; Johann, P. D. ; Hasselblatt, M. ; Paulus, W. ; Thomas, C. ; Dohmen, H. ; Baumhoer, D. ; Frank, S. ; Agaimy, A. ; Schüller, U. ; Vasudevaraja, V. ; Snuderl, M. ; Liu, C. Z. ; Pfister, D. G. ; Jungbluth, A. A. ; Ghossein, R. A. ; Xu, B. ; Capper, D. ; Dogan, S.
IDH2 R172 Mutations Across Poorly Differentiated Sinonasal Tract Malignancies: Forty Molecularly Homogenous and Histologically Variable Cases With Favorable Outcome.
The American journal of surgical pathology 45(9), 1190-1204 (2021) [10.1097/PAS.0000000000001697]2021 BibTeX | EndNote: XML, Text | RIS

Hemminki, K. (First author) ; Försti, A. ; Hemminki, A.
Survival in colon and rectal cancers in Finland and Sweden through 50 years.
BMJ open gastroenterology 8(1), e000644 (2021) [10.1136/bmjgast-2021-000644]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Asokan, S. (First author) ; Bandapalli, O. R. (Last author)
CXCL8 Signaling in the Tumor Microenvironment.
Advances in experimental medicine and biology 1302, 25-39 (2021) [10.1007/978-3-030-62658-7_3]2021 BibTeX | EndNote: XML, Text | RIS

Hau, P. ; Frappaz, D. ; Hovey, E. ; McCabe, M. G. ; Pajtler, K. W. ; Wiestler, B. ; Seidel, C. ; Combs, S. E. ; Dirven, L. ; Klein, M. ; Anazodo, A. ; Hattingen, E. ; Hofer, S. ; Pfister, S. M. ; Zimmer, C. ; Kortmann, R.-D. ; Sunyach, M.-P. ; Tanguy, R. ; Effeney, R. ; von Deimling, A. ; Sahm, F. ; Rutkowski, S. ; Berghoff, A. S. ; Franceschi, E. ; Pineda, E. ; Beier, D. ; Peeters, E. ; Gorlia, T. ; Vanlancker, M. ; Bromberg, J. E. C. ; Gautier, J. ; Ziegler, D. S. ; Preusser, M. ; Wick, W. ; Weller, M.
Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23.
Cancers 13(14), 3451 (2021) [10.3390/cancers13143451]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Koelsche, C. ; Benhamida, J. K. ; Kommoss, F. K. F. ; Stichel, D. ; Jones, D. ; Pfister, S. M. ; Heilig, C. E. ; Fröhling, S. ; Stenzinger, A. ; Buslei, R. ; Mentzel, T. ; Baumhoer, D. ; Ladanyi, M. ; Antonescu, C. R. ; Flucke, U. ; Gorp, J. v. ; Bode-Lesniewska, B. ; von Deimling, A. (Last author) ; Mechtersheimer, G.
Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature.
Modern pathology 34(12), 2122-2129 (2021) [10.1038/s41379-021-00874-y]2021 BibTeX | EndNote: XML, Text | RIS

Slater, E. P. ; Wilke, L. M. ; Böhm, L. B. ; Strauch, K. ; Lutz, M. ; Gercke, N. ; Matthäi, E. ; Hemminki, K. ; Försti, A. ; Schlesner, M. ; Paramasivam, N. ; Bartsch, D. K.
Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer
Journal of Personalized Medicine 11(7), 631 (2021) [10.3390/jpm11070631]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Steinbügl, M. ; Nemes, K. ; Johann, P. ; Kröncke, T. ; Tüchert, S. ; da Costa, M. J. G. ; Ebinger, M. ; Schüller, U. ; Sehested, A. ; Hauser, P. ; Reinhard, H. ; Sumerauer, D. ; Hettmer, S. ; Jakob, M. ; Hasselblatt, M. ; Siebert, R. ; Witt, O. ; Gerss, J. ; Kerl, K. ; Frühwald, M. C.
Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors.
Pediatric blood & cancer 68(12), e29267 (2021) [10.1002/pbc.29267]2021 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Henneken, S. (First author) ; Blume, C. ; et al
Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.
Acta neuropathologica 142(5), 827-839 (2021) [10.1007/s00401-021-02356-6]2021 BibTeX | EndNote: XML, Text | RIS

van Tilburg, C. M. ; Pfaff, E. ; Pajtler, K. W. ; et al
The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets.
Cancer discovery 11(11), 2764-2779 (2021) [10.1158/2159-8290.CD-21-0094]2021 BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Sundquist, K. ; Sundquist, J. ; Chen, T. ; Försti, A. ; Hemminki, A. ; Liska, V. ; Hemminki, K.
Second Primary Cancers After Liver, Gallbladder and Bile Duct Cancers, and These Cancers as Second Primary Cancers.
Clinical epidemiology 13, 683 - 691 (2021) [10.2147/CLEP.S318737]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hemminki, K. ; Försti, A. ; Houlston, R. ; Sud, A.
Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.
International journal of cancer 149(12), 1980-1996 (2021) [10.1002/ijc.33762]2021 BibTeX | EndNote: XML, Text | RIS

Hlap?i?, I. ; Grdi? Rajkovi?, M. ; ?eri, A. ; Dabeli?, S. ; Popovi?-Grle, S. ; Radi? Antolic, M. ; Kne?evi?, J. ; Försti, A. ; Rumora, L.
Increased HSP70 and TLR2 Gene Expression and Association of HSP70 rs6457452 Single Nucleotide Polymorphism with the Risk of Chronic Obstructive Pulmonary Disease in the Croatian Population
Diagnostics 11(8), 1412 (2021) [10.3390/diagnostics11081412]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Coltin, H. ; Sundaresan, L. ; Smith, K. S. ; Skowron, P. ; Massimi, L. ; Eberhart, C. G. ; Schreck, K. C. ; Gupta, N. ; Weiss, W. A. ; Tirapelli, D. ; Carlotti, C. ; Li, K. K. W. ; Ryzhova, M. ; Golanov, A. ; Zheludkova, O. ; Absalyamova, O. ; Okonechnikov, K. ; Stichel, D. ; von Deimling, A. ; Giannini, C. ; Raskin, S. ; Van Meir, E. G. ; Chan, J. A. ; Fults, D. ; Chambless, L. B. ; Kim, S.-K. ; Vasiljevic, A. ; Faure-Conter, C. ; Vibhakar, R. ; Jung, S. ; Leary, S. ; Mora, J. ; McLendon, R. E. ; Pollack, I. F. ; Hauser, P. ; Grajkowska, W. A. ; Rubin, J. B. ; van Veelen, M. C. ; French, P. J. ; Kros, J. M. ; Liau, L. M. ; Pfister, S. M. ; Kool, M. ; Kijima, N. ; Taylor, M. D. ; Packer, R. J. ; Northcott, P. A. ; Korshunov, A. (Last author) ; Ramaswamy, V.
Subgroup and subtype-specific outcomes in adult medulloblastoma.
Acta neuropathologica 142(5), 859-871 (2021) [10.1007/s00401-021-02358-4]2021 BibTeX | EndNote: XML, Text | RIS

Alhalabi, K. T. (First author) ; Stichel, D. ; Sievers, P. ; et al
PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.
Acta neuropathologica 142(5), 841-857 (2021) [10.1007/s00401-021-02354-8]2021 BibTeX | EndNote: XML, Text | RIS

Calandrini, C. ; van Hooff, S. R. ; Paassen, I. ; Ayyildiz, D. ; Derakhshan, S. ; Dolman, M. E. M. ; Langenberg, K. P. S. ; van de Ven, M. ; de Heus, C. ; Liv, N. ; Kool, M. ; de Krijger, R. R. ; Tytgat, G. A. M. ; van den Heuvel-Eibrink, M. M. ; Molenaar, J. J. ; Drost, J.
Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors.
Cell reports 36(8), 109568 (2021) [10.1016/j.celrep.2021.109568]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hemminki, K. ; Försti, A. ; Hansson, M.
Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016.
Scientific reports 11(1), 17272 (2021) [10.1038/s41598-021-96804-8]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Sarropoulos, I. ; Sepp, M. ; Frömel, R. ; Leiss, K. ; Trost, N. ; Leushkin, E. ; Okonechnikov, K. ; Joshi, P. K. ; Giere, P. ; Kutscher, L. ; Cardoso-Moreira, M. ; Pfister, S. (Last author) ; Kaessmann, H.
Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells.
Science 373(6558), eabg4696 - (2021) [10.1126/science.abg4696]2021 BibTeX | EndNote: XML, Text | RIS

Li, X. ; Koskinen, A. I. ; Hemminki, O. ; Försti, A. ; Sundquist, J. ; Sundquist, K. ; Hemminki, K.
Family History of Head and Neck Cancers.
Cancers 13(16), 4115 (2021) [10.3390/cancers13164115]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kirches, E. ; Sahm, F. ; Korshunov, A. ; Bluecher, C. ; Waldt, N. ; Kropf, S. ; Schrimpf, D. ; Sievers, P. ; Stichel, D. ; Schüller, U. ; Schittenhelm, J. ; Riemenschneider, M. J. ; Karajannis, M. A. ; Perry, A. ; Pietsch, T. ; Boekhoff, S. ; Capper, D. ; Beck, K. ; Paramasivam, N. ; Schlesner, M. ; Brastianos, P. K. ; Müller, H. L. ; Pfister, S. M. ; Mawrin, C.
Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.
Acta neuropathologica 142(5), 873-886 (2021) [10.1007/s00401-021-02351-x]2021 BibTeX | EndNote: XML, Text | RIS

Hemminki, K. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, A. ; Li, X.
Familial Risks and Proportions Describing Population Landscape of Familial Cancer.
Cancers 13(17), 4385 (2021) [10.3390/cancers13174385]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Panwalkar, P. ; Tamrazi, B. ; Dang, D. ; Chung, C. ; Sweha, S. ; Natarajan, S. K. ; Pun, M. ; Bayliss, J. ; Ogrodzinski, M. P. ; Pratt, D. ; Mullan, B. ; Hawes, D. ; Yang, F. ; Lu, C. ; Sabari, B. R. ; Achreja, A. ; Heon, J. ; Animasahun, O. ; Cieslik, M. ; Dunham, C. ; Yip, S. ; Hukin, J. ; Phillips, J. J. ; Bornhorst, M. ; Griesinger, A. M. ; Donson, A. M. ; Foreman, N. K. ; Garton, H. J. L. ; Heth, J. ; Muraszko, K. ; Nazarian, J. ; Koschmann, C. ; Jiang, L. ; Filbin, M. G. ; Nagrath, D. ; Kool, M. ; Korshunov, A. ; Pfister, S. ; Gilbertson, R. J. ; Allis, C. D. ; Chinnaiyan, A. M. ; Lunt, S. Y. ; Blüml, S. ; Judkins, A. R. ; Venneti, S.
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Science translational medicine 13(614), eabc0497 (2021) [ doi: 10.1126/scitranslmed.abc0497]2021 BibTeX | EndNote: XML, Text | RIS

Marcu, A. ; Schlosser, A. ; Keupp, A. ; Trautwein, N. ; Johann, P. ; Wölfl, M. ; Lager, J. ; Monoranu, C. M. ; Walz, J. S. ; Henkel, L. M. ; Krauß, J. ; Ebinger, M. ; Schuhmann, M. ; Thomale, U. W. ; Pietsch, T. ; Klinker, E. ; Schlegel, P. G. ; Oyen, F. ; Reisner, Y. ; Rammensee, H.-G. ; Eyrich, M.
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors.
Journal for ImmunoTherapy of Cancer 9(10), e003404 (2021) [10.1136/jitc-2021-003404]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hirsch, S. ; Dikow, N. ; Pfister, S. M. ; Pajtler, K. (Last author)
Cancer predisposition in pediatric neuro-oncology-practical approaches and ethical considerations.
Neuro-oncology practice 8(5), 526 - 538 (2021) [10.1093/nop/npab031]2021 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Deng, M. Y. (First author) ; Sturm, D. (First author) ; Pfaff, E. (First author) ; Sill, M. ; Stichel, D. ; Balasubramanian, G. P. ; Tippelt, S. ; Kramm, C. ; Donson, A. M. ; Green, A. L. ; Jones, C. ; Schittenhelm, J. ; Ebinger, M. ; Schuhmann, M. U. ; Jones, B. C. ; van Tilburg, C. M. ; Wittmann, A. ; Golanov, A. ; Ryzhova, M. ; Ecker, J. ; Milde, T. ; Witt, O. ; Sahm, F. ; Reuss, D. ; Sumerauer, D. ; Zamecnik, J. ; Korshunov, A. ; von Deimling, A. ; Pfister, S. M. ; Jones, D. (Last author)
Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B.
Nature Communications 12(1), 5530 (2021) [10.1038/s41467-021-25708-y]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Stichel, D. (First author) ; Sill, M. ; Schrimpf, D. ; Sturm, D. ; Selt, F. ; Ecker, J. ; Kazdal, D. ; Miele, E. ; Kranendonk, M. E. G. ; Tops, B. B. J. ; Kohlhof-Meinecke, P. ; Beschorner, R. ; Kramm, C. M. ; Hasselblatt, M. ; Reifenberger, G. ; Capper, D. ; Wesseling, P. ; Stenzinger, A. ; Milde, T. ; Korshunov, A. ; Witt, O. ; Pfister, S. M. ; Wick, W. ; von Deimling, A. ; Jones, D. T. W. ; Sahm, F. (Last author)
GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Acta neuropathologica 142(6), 1065-1069 (2021) [10.1007/s00401-021-02369-1]2021 BibTeX | EndNote: XML, Text | RIS

Benzel, J. (First author) ; Bajraktari-Sylejmani, G. ; Uhl, P. ; Davis, A. ; Nair, S. ; Pfister, S. M. ; Haefeli, W. E. ; Weiss, J. ; Burhenne, J. ; Pajtler, K. W. ; Sauter, M.
Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification.
Pharmaceutics 13(9), 1498 (2021) [10.3390/pharmaceutics13091498]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Maas, S. L. N. (First author) ; Stichel, D. ; Hielscher, T. ; et al
Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.
Journal of clinical oncology 39(34), 3839-3852 (2021) [10.1200/JCO.21.00784]2021 BibTeX | EndNote: XML, Text | RIS

Daub, J. T. ; Amini, S. ; Kersjes, D. J. E. ; Ma, X. ; Jäger, N. ; Zhang, J. ; Pfister, S. M. ; Holstege, F. C. P. ; Kemmeren, P.
A systematic analysis of genetic interactions and their underlying biology in childhood cancer.
Communications biology 4(1), 1139 (2021) [10.1038/s42003-021-02647-4]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Adolph, J. E. ; Fleischhack, G. ; Gaab, C. ; Mikasch, R. ; Mynarek, M. ; Rutkowski, S. ; Schüller, U. ; Pfister, S. M. ; Pajtler, K. ; Milde, T. ; Witt, O. ; Bison, B. ; Warmuth-Metz, M. ; Kortmann, R.-D. ; Dietzsch, S. ; Pietsch, T. ; Timmermann, B. ; Tippelt, S. ; HIT-Network, G. G. (Collaboration Author)
Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies.
Journal of neuro-oncology 155(2), 193-202 (2021) [10.1007/s11060-021-03867-8]2021 BibTeX | EndNote: XML, Text | RIS

Schmid, S. ; Solomon, D. A. ; Perez, E. ; Thieme, A. ; Kleinschmidt-DeMasters, B. K. ; Giannini, C. ; Reinhardt, A. ; Asa, S. L. ; Mete, O. ; Stichel, D. ; Siewert, C. ; Dittmayer, C. ; Hasselblatt, M. ; Paulus, W. ; Nagel, C. ; Harter, P. ; Schittenhelm, J. ; Honegger, J. ; Rushing, E. ; Coras, R. ; Pfister, S. M. ; Buslei, R. ; Koch, A. ; Perry, A. ; Jones, D. T. W. ; von Deimling, A. ; Capper, D. ; Lopes, M. B.
Genetic and epigenetic characterization of posterior pituitary tumors.
Acta neuropathologica 142(6), 1025-1043 (2021) [10.1007/s00401-021-02377-1]2021 BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Chattopadhyay, S. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, A. ; Hemminki, K. (Last author)
Types of second primary cancer influence overall survival in cutaneous melanoma.
BMC cancer 21(1), 1123 (2021) [10.1186/s12885-021-08845-x]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Liu, A. P. Y. ; Smith, K. S. ; Kumar, R. ; Paul, L. ; Bihannic, L. ; Lin, T. ; Maass, K. K. ; Pajtler, K. W. ; Chintagumpala, M. ; Su, J. M. ; Bouffet, E. ; Fisher, M. J. ; Gururangan, S. ; Cohn, R. ; Hassall, T. ; Hansford, J. R. ; Klimo, P. ; Boop, F. A. ; Stewart, C. F. ; Harreld, J. H. ; Merchant, T. E. ; Tatevossian, R. G. ; Neale, G. ; Lear, M. ; Klco, J. M. ; Orr, B. A. ; Ellison, D. W. ; Gilbertson, R. J. ; Onar-Thomas, A. ; Gajjar, A. ; Robinson, G. W. ; Northcott, P. A.
Serial assessment of measurable residual disease in medulloblastoma liquid biopsies.
Cancer cell 39(11), 1519-1530.e4 (2021) [10.1016/j.ccell.2021.09.012]2021 BibTeX | EndNote: XML, Text | RIS

Riedmeier, M. ; Stock, A. ; Krauß, J. ; Sahm, F. ; Jones, D. T. W. ; Sturm, D. ; Kramm, C. M. ; Eyrich, M. ; Härtel, C. ; Schlegel, S. ; Schlegel, P. G. ; Monoranu, C.-M. ; Wiegering, V.
Spontaneous regression of a congenital high-grade glioma-a case report.
Neuro-oncology advances 3(1), vdab120 (2021) [10.1093/noajnl/vdab120]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Huang, Y. ; Qi, L. ; Kogiso, M. ; Du, Y. ; Braun, F. K. ; Zhang, H. ; Huang, L. F. ; Xiao, S. ; Teo, W.-Y. ; Lindsay, H. ; Zhao, S. ; Baxter, P. ; Su, J. M. F. ; Adesina, A. ; Yang, J. ; Brabetz, S. ; Kool, M. ; Pfister, S. M. ; Chintagumpala, M. ; Perlaky, L. ; Wang, Z. ; Zhou, Y. ; Man, T.-K. ; Li, X.-N.
Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.
Advanced science 8(23), e2101923 (2021) [10.1002/advs.202101923]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Khandanpour, C. ; Eisfeld, C. ; Nimmagadda, S. C. ; Raab, M. S. ; Weinhold, N. ; Seckinger, A. ; Hose, D. ; Jauch, A. ; Försti, A. ; Hemminki, K. ; Hielscher, T. ; Hummel, M. ; Lenz, G. ; Goldschmidt, H. ; Huhn, S.
Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis.
Frontiers in oncology 11, 757664 (2021) [10.3389/fonc.2021.757664]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Franceschi, E. ; Seidel, C. ; Sahm, F. ; Pajtler, K. W. ; Hau, P.
Erratum to 'How we treat medulloblastoma in adults': [ESMO Open Volume 6, Issue 4, August 2021, 100173].
ESMO open 6(6), 100327 (2021) [10.1016/j.esmoop.2021.100327]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hemminki, K. (First author) ; Försti, A. ; Chen, T. ; Hemminki, A.
Incidence, mortality and survival in malignant pleural mesothelioma before and after asbestos in Denmark, Finland, Norway and Sweden.
BMC cancer 21(1), 1189 (2021) [10.1186/s12885-021-08913-2]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kaur, A. ; Chopra, M. ; Bhushan, M. ; Gupta, S. ; Kumari P, H. ; Sivagurunathan, N. ; Shukla, N. ; Rajagopal, S. ; Bhalothia, P. ; Sharma, P. ; Naravula, J. ; Suravajhala, R. ; Gupta, A. ; Abbasi, B. A. ; Goswami, P. ; Singh, H. ; Narang, R. ; Polavarapu, R. ; Medicherla, K. M. ; Valadi, J. ; Kumar S, A. ; Chaubey, G. ; Singh, K. K. ; Bandapalli, O. R. ; Kavi Kishor, P. B. ; Suravajhala, P.
The Omic Insights on Unfolding Saga of COVID-19.
Frontiers in immunology 12, 724914 (2021) [10.3389/fimmu.2021.724914]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Duran-Lozano, L. ; Thorleifsson, G. ; Lopez de Lapuente Portilla, A. ; Niroula, A. ; Went, M. ; Thodberg, M. ; Pertesi, M. ; Ajore, R. ; Cafaro, C. ; Olason, P. I. ; Stefansdottir, L. ; Bragi Walters, G. ; Halldorsson, G. H. ; Turesson, I. ; Kaiser, M. F. ; Försti, A. ; Weinhold, N. ; Abildgaard, N. ; Andersen, N. F. ; Mellqvist, U.-H. ; Waage, A. ; Juul-Vangsted, A. ; Thorsteinsdottir, U. ; Hansson, M. ; Houlston, R. ; Rafnar, T. ; Stefansson, K. ; Nilsson, B.
Author Correction: Germline variants at SOHLH2 influence multiple myeloma risk
Blood cancer journal 11(11), 181 (2021) [10.1038/s41408-021-00575-4]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Willscher, E. ; Hopp, L. ; Kreuz, M. ; Schmidt, M. ; Hakobyan, S. ; Arakelyan, A. ; Hentschel, B. ; Jones, D. T. W. ; Pfister, S. M. ; Loeffler, M. ; Loeffler-Wirth, H. ; Binder, H.
High-Resolution Cartography of the Transcriptome and Methylome Landscapes of Diffuse Gliomas.
Cancers 13(13), 3198 (2021) [10.3390/cancers13133198]2021 DBCoverage Fulltext Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Niazi, Y. (First author) ; Thomsen, H. ; Smolkova, B. ; Vodickova, L. ; Vodenkova, S. ; Kroupa, M. ; Vymetalkova, V. ; Kazimirova, A. ; Barancokova, M. ; Volkovova, K. ; Staruchova, M. ; Hoffmann, P. ; Nöthen, M. M. ; Dusinska, M. ; Musak, L. ; Vodicka, P. ; Hemminki, K. ; Försti, A. (Last author)
DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations.
Frontiers in genetics 12, 691947 (2021) [10.3389/fgene.2021.691947]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Whitehouse, J. P. ; Howlett, M. ; Federico, A. ; Kool, M. ; Endersby, R. ; Gottardo, N. G.
Defining the molecular features of radiation-induced glioma: A systematic review and meta-analysis.
Neuro-oncology advances 3(1), vdab109 (2021) [10.1093/noajnl/vdab109]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K.
Family history of any cancer for childhood leukemia patients in Sweden
eJHaem 2(3), 421 - 427 (2021) [10.1002/jha2.166]2021 BibTeX | EndNote: XML, Text | RIS

?uti?, M. ; Vuki?, A. ; Barana?i?, J. ; Försti, A. ; D?ubur, F. ; Samar?ija, M. ; Jakopovi?, M. ; Br?i?, L. ; Kne?evi?, J.
Diagnostic, Predictive, and Prognostic Biomarkers in Non-Small Cell Lung Cancer (NSCLC) Management
Journal of Personalized Medicine 11(11), 1102 (2021) [10.3390/jpm11111102]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Shatara, M. ; Schieffer, K. M. ; Klawinski, D. ; Thomas, D. L. ; Pierson, C. R. ; Sribnick, E. A. ; Jones, J. ; Rodriguez, D. P. ; Deeg, C. ; Hamelberg, E. ; LaHaye, S. ; Miller, K. E. ; Fitch, J. ; Kelly, B. ; Leraas, K. ; Pfau, R. ; White, P. ; Magrini, V. ; Wilson, R. K. ; Mardis, E. R. ; Abdelbaki, M. S. ; Finlay, J. L. ; Boué, D. R. ; Cottrell, C. E. ; Ghasemi, D. R. ; Pajtler, K. W. ; Osorio, D. S.
Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas.
Acta Neuropathologica Communications 9(1), 192 (2021) [10.1186/s40478-021-01296-2]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Williamson, L. M. ; Rive, C. M. ; Di Francesco, D. ; Titmuss, E. ; Chun, H. E. ; Brown, S. D. ; Milne, K. ; Pleasance, E. ; Lee, A. F. ; Yip, S. ; Rosenbaum, D. G. ; Hasselblatt, M. ; Johann, P. D. ; Kool, M. ; Harvey, M. ; Dix, D. ; Renouf, D. J. ; Holt, R. A. ; Nelson, B. H. ; Hirst, M. ; Jones, S. J. M. ; Laskin, J. ; Rassekh, S. R. ; Deyell, R. J. ; Marra, M. A.
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.
npj precision oncology 5(1), 103 (2021) [10.1038/s41698-021-00238-4]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Ryzhova, M. V. ; Telysheva, E. N. ; Shaikhaev, E. G. ; Starovoitov, D. V. ; Kotelnikova, A. O. ; Galstyan, S. A. ; Okonechnikov, K. (Last author)
Sovremennye diagnosticheskie vozmozhnosti molekulyarnogo issledovaniya opukholei mozga v Tsentre neirokhirurgii im. akad. N.N. Burdenko.
Zurnal voprosy nejrochirurgii imeni N.N. Burdenko 85(6), 98 (2021) [10.17116/neiro20218506198]2021 BibTeX | EndNote: XML, Text | RIS

Voellger, B. ; Zhang, Z. ; Benzel, J. ; Wang, J. ; Lei, T. ; Nimsky, C. ; Bartsch, J.-W.
Targeting Aggressive Pituitary Adenomas at the Molecular Level-A Review.
Journal of Clinical Medicine 11(1), 124 (2021) [10.3390/jcm11010124]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hill, R. M. ; Plasschaert, S. L. A. ; Timmermann, B. ; Dufour, C. ; Aquilina, K. ; Avula, S. ; Donovan, L. ; Lequin, M. ; Pietsch, T. ; Thomale, U. ; Tippelt, S. ; Wesseling, P. ; Rutkowski, S. ; Clifford, S. C. ; Pfister, S. M. ; Bailey, S. ; Fleischhack, G.
Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment.
Cancers 14(1), 126 (2021) [10.3390/cancers14010126]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

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