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Publications 2020

Rheinbay, E. ; Nielsen, M. M. ; Abascal, F. ; et al
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Nature <London> 578(7793), 102 - 111 (2020) [10.1038/s41586-020-1965-x]2020 BibTeX | EndNote: XML, Text | RIS

Li, C. H. ; Prokopec, S. D. ; Sun, R. X. ; et al
Sex differences in oncogenic mutational processes
Nature Communications 11(1), 4330 (2020) [10.1038/s41467-020-17359-2]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Cmero, M. ; Yuan, K. ; Ong, C. S. ; Schröder, J. ; PCAWG, E. ; Heterogeneity Working, G. ; Corcoran, N. M. ; Papenfuss, T. ; Hovens, C. M. ; Markowetz, F. ; Macintyre, G. ; PCAWGConsortium
Inferring structural variant cancer cell fraction.
Nature Communications 11(1), 730 (2020) [10.1038/s41467-020-14351-8]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Jiao, W. ; Atwal, G. ; Polak, P. ; Karlic, R. ; Cuppen, E. ; PCAWGTumorSubtypesClinicalTranslationWorkingGroup ; Danyi, A. ; de Ridder, J. ; van Herpen, C. ; Lolkema, M. P. ; Steeghs, N. ; Getz, G. ; Morris, Q. ; Stein, L. D. ; PCAWGConsortium
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Nature Communications 11(1), 728 (2020) [10.1038/s41467-019-13825-8]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Reyna, M. A. ; Haan, D. ; Paczkowska, M. ; Verbeke, L. P. C. ; Vazquez, M. ; Kahraman, A. ; Pulido-Tamayo, S. ; Barenboim, J. ; Wadi, L. ; Dhingra, P. ; Shrestha, R. ; Getz, G. ; Lawrence, M. S. ; Pedersen, J. S. ; Rubin, M. A. ; Wheeler, D. A. ; Brunak, S. ; Izarzugaza, J. M. G. ; Khurana, E. ; Marchal, K. ; von Mering, C. ; Sahinalp, S. C. ; Valencia, A. ; Drivers, P. ; FunctionalInterpretationWorkingGroup ; Reimand, J. ; Stuart, J. M. ; Raphael, B. J. ; PCAWGConsortium
Pathway and network analysis of more than 2500 whole cancer genomes.
Nature Communications 11(1), 729 (2020) [10.1038/s41467-020-14367-0]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Rubanova, Y. ; Shi, R. ; Harrigan, C. F. ; Li, R. ; Wintersinger, J. ; Sahin, N. ; Deshwar, A. ; PCAWGEvolution ; Group, H. W. ; Morris, Q. ; PCAWGConsortium
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig.
Nature Communications 11(1), 731 (2020) [10.1038/s41467-020-14352-7]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Bhandari, V. ; Li, C. H. ; Bristow, R. G. ; Boutros, P. C. ; PCAWGConsortium
Divergent mutational processes distinguish hypoxic and normoxic tumours.
Nature Communications 11(1), 737 (2020) [10.1038/s41467-019-14052-x]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Shuai, S. ; PCAWGDrivers ; FunctionalInterpretationWorkingGroup ; Gallinger, S. ; Stein, L. ; PCAWGConsortium
Combined burden and functional impact tests for cancer driver discovery using DriverPower.
Nature Communications 11(1), 734 (2020) [10.1038/s41467-019-13929-1]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Paczkowska, M. ; Barenboim, J. ; Sintupisut, N. ; Fox, N. S. ; Zhu, H. ; Abd-Rabbo, D. ; Mee, M. W. ; Boutros, P. C. ; Drivers, P. ; FunctionalInterpretationWorkingGroup ; Reimand, J. ; PCAWGConsortium
Integrative pathway enrichment analysis of multivariate omics data.
Nature Communications 11(1), 735 (2020) [10.1038/s41467-019-13983-9]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Alexandrov, L. B. ; Kim, J. ; Haradhvala, N. J. ; Huang, M. N. ; Tian Ng, A. W. ; Wu, Y. ; Boot, A. ; Covington, K. R. ; Gordenin, D. A. ; Bergstrom, E. N. ; Islam, S. M. A. ; Lopez-Bigas, N. ; Klimczak, L. J. ; McPherson, J. R. ; Morganella, S. ; Sabarinathan, R. ; Wheeler, D. A. ; Mustonen, V. ; PCAWGMutationalSignaturesWorkingGroup ; Getz, G. ; Rozen, S. G. ; Stratton, M. R. ; PCAWGConsortium
The repertoire of mutational signatures in human cancer.
Nature <London> 578(7793), 94 - 101 (2020) [10.1038/s41586-020-1943-3]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Zhang, Y. ; Chen, F. ; Fonseca, N. A. ; He, Y. ; Fujita, M. ; Nakagawa, H. ; Zhang, Z. ; Brazma, A. ; PCAWGTranscriptomeWorkingGroup ; PCAWGStructuralVariationWorkingGroup ; Creighton, C. J. ; PCAWGConsortium
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Nature Communications 11(1), 736 (2020) [10.1038/s41467-019-13885-w]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Mayr, L. ; Guntner, A. S. ; Madlener, S. ; Schmook, M. T. ; Peyrl, A. ; Azizi, A. A. ; Dieckmann, K. ; Reisinger, D. ; Stepien, N. M. ; Schramm, K. ; Laemmerer, A. ; Jones, D. T. W. ; Ecker, J. ; Sahm, F. ; Milde, T. ; Pajtler, K. W. ; Blattner-Johnson, M. ; Strbac, M. ; Dorfer, C. ; Czech, T. ; Kirchhofer, D. ; Gabler, L. ; Berger, W. ; Haberler, C. ; Müllauer, L. ; Buchberger, W. ; Slavc, I. ; Lötsch-Gojo, D. ; Gojo, J. (Last author)
Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK-Fusion Positive Pediatric High-Grade Glioma
Journal of Personalized Medicine 10(4), 290 (2020) [10.3390/jpm10040290]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Chen, C. C. L. ; Deshmukh, S. ; Jessa, S. ; et al
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
Cell 183(6), 1617-1633.e22 (2020) [10.1016/j.cell.2020.11.012]2020 BibTeX | EndNote: XML, Text | RIS

Cortés-Ciriano, I. ; Lee, J. J. ; Xi, R. ; Jain, D. ; Jung, Y. L. ; Yang, L. ; Gordenin, D. ; Klimczak, L. J. ; Zhang, C.-Z. ; Pellman, D. S. ; Park, P. J.
Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature genetics nn, nn (2020) [10.1038/s41588-020-0634-1]2020 BibTeX | EndNote: XML, Text | RIS

Bailey, M. H. ; Meyerson, W. U. ; Dursi, L. J. ; et al
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Nature Communications 11(1), 4748 (2020) [10.1038/s41467-020-18151-y]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Selt, F. (First author) ; van Tilburg, C. M. ; Bison, B. ; Sievers, P. ; Harting, I. ; Ecker, J. ; Pajtler, K. W. ; Sahm, F. ; Bahr, A. ; Simon, M. ; Jones, D. T. W. ; Well, L. ; Mautner, V.-F. ; Capper, D. ; Hernáiz Driever, P. ; Gnekow, A. ; Pfister, S. M. ; Witt, O. ; Milde, T. (Last author)
Response to trametinib treatment in progressive pediatric low-grade glioma patients.
Journal of neuro-oncology 149(3), 499-510 (2020) [10.1007/s11060-020-03640-3]2020 BibTeX | EndNote: XML, Text | RIS

Li, Y. ; Roberts, N. D. ; Wala, J. A. ; Shapira, O. ; Schumacher, S. E. ; Kumar, K. ; Khurana, E. ; Waszak, S. ; Korbel, J. O. ; Haber, J. E. ; Imielinski, M. ; PCAWGStructuralVariationWorkingGroup ; Weischenfeldt, J. ; Beroukhim, R. ; Campbell, P. J. ; PCAWGConsortium
Patterns of somatic structural variation in human cancer genomes.
Nature <London> 578(7793), 112 - 121 (2020) [10.1038/s41586-019-1913-9]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Dodgshun, A. J. ; Fukuoka, K. ; Edwards, M. ; Bianchi, V. J. ; Das, A. ; Sexton-Oates, A. ; Larouche, V. ; Vanan, M. I. ; Lindhorst, S. ; Yalon, M. ; Mason, G. ; Crooks, B. ; Constantini, S. ; Massimino, M. ; Chiaravalli, S. ; Ramdas, J. ; Mason, W. ; Ashraf, S. ; Farah, R. ; Van Damme, A. ; Opocher, E. ; Hamid, S. A. ; Ziegler, D. S. ; Samuel, D. ; Cole, K. A. ; Tomboc, P. ; Stearns, D. ; Thomas, G. A. ; Lossos, A. ; Sullivan, M. ; Hansford, J. R. ; Mackay, A. ; Jones, C. ; Jones, D. T. W. ; Ramaswamy, V. ; Hawkins, C. ; Bouffet, E. ; Tabori, U.
Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns.
Acta neuropathologica 140(5), 765-776 (2020) [10.1007/s00401-020-02209-8]2020 BibTeX | EndNote: XML, Text | RIS

Fittall, M. W. ; Lyskjaer, I. ; Ellery, P. ; Lombard, P. ; Ijaz, J. ; Strobl, A.-C. ; Oukrif, D. ; Tarabichi, M. ; Sill, M. ; Koelsche, C. ; Mechtersheimer, G. ; Demeulemeester, J. ; Tirabosco, R. ; Amary, F. ; Campbell, P. J. ; Pfister, S. ; Jones, D. T. W. ; Pillay, N. ; Van Loo, P. ; Behjati, S. ; Flanagan, A. M.
Drivers underpinning the malignant transformation of giant cell tumour of bone.
The journal of pathology 252(4), 433-440 (2020) [10.1002/path.5537]2020 BibTeX | EndNote: XML, Text | RIS

Banan, R. ; Stichel, D. ; Bleck, A. ; Hong, B. ; Lehmann, U. ; Suwala, A. ; Reinhardt, A. ; Schrimpf, D. ; Buslei, R. ; Stadelmann, C. ; Ehlert, K. ; Prinz, M. ; Acker, T. ; Schittenhelm, J. ; Kaul, D. ; Schweizer, L. ; Capper, D. ; Harter, P. ; Etminan, N. ; Jones, D. T. W. ; Pfister, S. M. ; Herold-Mende, C. ; Wick, W. ; Sahm, F. ; von Deimling, A. ; Hartmann, C. ; Reuß, D. (Last author)
Infratentorial IDH-mutant astrocytoma is a distinct subtype.
Acta neuropathologica 140(4), 569-581 (2020) [10.1007/s00401-020-02194-y]2020 BibTeX | EndNote: XML, Text | RIS

Sommerkamp, A. (First author) ; Uhrig, S. ; Stichel, D. ; St-Onge, P. ; Sun, P. ; Jäger, N. ; von Deimling, A. ; Sahm, F. ; Pfister, S. M. ; Korshunov, A. ; Sinnett, D. ; Jabado, N. ; Wefers, A. K. ; Jones, D. (Last author)
An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data.
Acta neuropathologica 140(2), 237-239 (2020) [10.1007/s00401-020-02167-1]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Hielscher, T. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Berghoff, A. S. ; Neidert, M. C. ; Wirsching, H.-G. ; Mawrin, C. ; Ketter, R. ; Paulus, W. ; Reifenberger, G. ; Lamszus, K. ; Westphal, M. ; Etminan, N. ; Ratliff, M. ; Herold-Mende, C. ; Pfister, S. M. ; Jones, D. T. W. ; Weller, M. ; Harter, P. N. ; Wick, W. ; Preusser, M. ; von Deimling, A. ; Sahm, F. (Last author)
CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.
Acta neuropathologica 140(3), 409-413 (2020) [10.1007/s00401-020-02188-w]2020 BibTeX | EndNote: XML, Text | RIS

Usta, D. (First author) ; Sigaud, R. ; Buhl, J. L. ; Selt, F. ; Marquardt, V. ; Pauck, D. ; Jansen, J. ; Pusch, S. ; Ecker, J. ; Hielscher, T. ; Vollmer, J. ; Sommerkamp, A. C. ; Rubner, T. ; Hargrave, D. ; van Tilburg, C. M. ; Pfister, S. M. ; Jones, D. T. W. ; Remke, M. ; Brummer, T. ; Witt, O. ; Milde, T. (Last author)
A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells.
Molecular cancer therapeutics 19(8), 1736-1750 (2020) [10.1158/1535-7163.MCT-19-1021]2020 BibTeX | EndNote: XML, Text | RIS

Appay, R. ; Pages, M. ; Colin, C. ; Jones, D. T. W. ; Varlet, P. ; Figarella-Branger, D.
Diffuse leptomeningeal glioneuronal tumor: a double misnomer? A report of two cases.
Acta Neuropathologica Communications 8(1), 95 (2020) [10.1186/s40478-020-00978-7]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

ICGC/TCGAPan-CancerAnalysisofWholeGenomesConsortium
Pan-cancer analysis of whole genomes.
Nature <London> 578(7793), 82 - 93 (2020) [10.1038/s41586-020-1969-6]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

van Tilburg, C. M. (First author) ; Witt, R. ; Heiss, M. ; Pajtler, K. W. ; Plass, C. ; Poschke, I. ; Platten, M. ; Harting, I. ; Sedlaczek, O. ; Freitag, A. ; Meyrath, D. ; Taylor, L. ; Balasubramanian, G. P. ; Jäger, N. ; Pfaff, E. ; Jones, B. C. ; Milde, T. ; Pfister, S. M. ; Jones, D. T. W. ; Kopp-Schneider, A. ; Witt, O. (Last author)
INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies
BMC cancer 20(1), 523 (2020) [10.1186/s12885-020-07008-8]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Kommoss, F. K. ; Chang, K. T. ; Stichel, D. ; Banito, A. ; Jones, D. ; Heilig, C. ; Fröhling, S. ; Sahm, F. ; Stenzinger, A. ; Hartmann, W. ; Mechtersheimer, G. ; Sinn, H.-P. ; Schmidt, D. ; Kommoss, F. K. ; von Deimling, A. (Last author) ; Koelsche, C.
Endometrial stromal sarcomas with BCOR-rearrangement harbor MDM2 amplifications.
The journal of pathology: clinical research 6(3), 178-184 (2020) [10.1002/cjp2.165]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Waszak, S. ; Robinson, G. ; Gudenas, B. L. ; et al
Germline Elongator mutations in Sonic Hedgehog medulloblastoma
Nature <London> 580(7803), 396 - 401 (2020) [10.1038/s41586-020-2164-5]2020 BibTeX | EndNote: XML, Text | RIS

Clarke, M. ; Mackay, A. ; Ismer, B. ; et al
Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes.
Cancer discovery 10(7), 942-963 (2020) [10.1158/2159-8290.CD-19-1030]2020 BibTeX | EndNote: XML, Text | RIS

Schubert, N. A. ; Lowery, C. D. ; Bergthold, G. ; Koster, J. ; Eleveld, T. F. ; Rodríguez, A. ; Jones, D. T. W. ; German Cancer Research Center , H. (DKFZ) ; Vassal, G. ; Stancato, L. F. ; Pfister, S. M. ; German Cancer Research Center , H. (DKFZ) ; Heidelberg University Hospital, H. ; Caron, H. N. ; Molenaar, J. J.
Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers.
European journal of cancer 130, 168 - 181 (2020) [10.1016/j.ejca.2020.01.027]2020 BibTeX | EndNote: XML, Text | RIS

Castel, D. ; Kergrohen, T. ; Tauziède-Espariat, A. ; Mackay, A. ; Ghermaoui, S. ; Lechapt, E. ; Pfister, S. M. ; Kramm, C. M. ; Boddaert, N. ; Blauwblomme, T. ; Puget, S. ; Beccaria, K. ; Jones, C. ; Jones, D. T. W. ; Varlet, P. ; Grill, J. ; Debily, M.-A.
Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation.
Acta neuropathologica 139(5), 1109-1113 (2020) [10.1007/s00401-020-02142-w]2020 BibTeX | EndNote: XML, Text | RIS

Aichmüller, C. (First author) ; Iskar, M. ; Jones, D. T. W. ; Korshunov, A. ; Radlwimmer, B. ; Kool, M. ; Ernst, A. ; Pfister, S. M. ; Lichter, P. ; Zapatka, M. (Last author)
Pilocytic Astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response.
Neuro-Oncology 22(9), 1327-1338 (2020) [10.1093/neuonc/noaa035]2020 BibTeX | EndNote: XML, Text | RIS

Cortés-Ciriano, I. ; Lee, J. J. ; Xi, R. ; et al
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.
Nature genetics 52(3), 331-341 (2020) [10.1038/s41588-019-0576-7]2020 BibTeX | EndNote: XML, Text | RIS

Akdemir, K. C. ; Le, V. T. ; Chandran, S. ; et al
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer.
Nature genetics 52(3), 294-305 (2020) [10.1038/s41588-019-0564-y]2020 BibTeX | EndNote: XML, Text | RIS

Rodriguez-Martin, B. ; Alvarez, E. G. ; Baez-Ortega, A. ; et al
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Nature genetics 52(3), 306-319 (2020) [10.1038/s41588-019-0562-0]2020 BibTeX | EndNote: XML, Text | RIS

Packer, R. J. ; Iavarone, A. ; Jones, D. T. W. ; Blakeley, J. O. ; Bouffet, E. ; Fisher, M. J. ; Hwang, E. ; Hawkins, C. ; Kilburn, L. ; MacDonald, T. ; Pfister, S. M. ; Rood, B. ; Rodriguez, F. J. ; Tabori, U. ; Ramaswamy, V. ; Zhu, Y. ; Fangusaro, J. ; Johnston, S. A. ; Gutmann, D. H.
Implications of New Understandings of Gliomas in Children and Adults with NF1: Report of a Consensus Conference.
Neuro-Oncology 22(6), 773-784 (2020) [10.1093/neuonc/noaa036]2020 BibTeX | EndNote: XML, Text | RIS

Sieverling, L. (First author) ; Hong, C. ; Koser, S. D. ; et al
Genomic footprints of activated telomere maintenance mechanisms in cancer.
Nature Communications 11(1), 733 (2020) [10.1038/s41467-019-13824-9]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Gerstung, M. ; Jolly, C. ; Leshchiner, I. ; Dentro, S. ; Gonzalez, S. ; Rosebrock, D. ; Mitchell, T. J. ; Rubanova, Y. ; Anur, P. ; Yu, K. ; Tarabichi, M. ; Deshwar, A. ; Wintersinger, J. ; Kleinheinz, K. ; Vázquez-García, I. ; Haase, K. ; Jerman, L. ; Sengupta, S. ; Macintyre, G. ; Malikic, S. ; Donmez, N. ; Livitz, D. G. ; Cmero, M. ; Demeulemeester, J. ; Schumacher, S. ; Fan, Y. ; Yao, X. ; Lee, J. ; Schlesner, M. ; Boutros, P. C. ; Bowtell, D. D. ; Zhu, H. ; Getz, G. ; Imielinski, M. ; Beroukhim, R. ; Sahinalp, S. C. ; Ji, Y. ; Peifer, M. ; Markowetz, F. ; Mustonen, V. ; Yuan, K. ; Wang, W. ; Morris, Q. D. ; PCAWGEvolution&HeterogeneityWorkingGroup ; Spellman, P. T. ; Wedge, D. C. ; Van Loo, P. ; PCAWGConsortium
The evolutionary history of 2,658 cancers.
Nature <London> 578(7793), 122 - 128 (2020) [10.1038/s41586-019-1907-7]2020 BibTeX | EndNote: XML, Text | RIS

Group, P. T. C. (Collaboration Author) ; Calabrese, C. ; Davidson, N. R. ; et al
Genomic basis for RNA alterations in cancer.
Nature <London> 578(7793), 129 - 136 (2020) [10.1038/s41586-020-1970-0]2020 BibTeX | EndNote: XML, Text | RIS

Maros, M. E. ; Capper, D. ; Jones, D. T. W. ; Hovestadt, V. ; von Deimling, A. ; Pfister, S. M. ; Benner, A. ; Zucknick, M. ; Sill, M. (Last author)
Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data.
Nature protocols 15(2), 479-512 (2020) [10.1038/s41596-019-0251-6]2020 BibTeX | EndNote: XML, Text | RIS

Deng, M. Y. (First author) ; Sill, M. ; Sturm, D. ; Stichel, D. ; Witt, H. ; Ecker, J. ; Wittmann, A. ; Schittenhelm, J. ; Ebinger, M. ; Schuhmann, M. U. ; Figarella-Branger, D. ; Aronica, E. ; Staszewski, O. ; Preusser, M. ; Haberler, C. ; Lauten, M. ; Schüller, U. ; Hartmann, C. ; Snuderl, M. ; Dunham, C. ; Jabado, N. ; Wesseling, P. ; Deckert, M. ; Keyvani, K. ; Gottardo, N. ; Giangaspero, F. ; von Hoff, K. ; Ellison, D. W. ; Pietsch, T. ; Herold Mende, C. ; Milde, T. ; Witt, O. ; Kool, M. ; Korshunov, A. ; Wick, W. ; von Deimling, A. ; Pfister, S. M. ; Jones, D. T. W. ; Sahm, F. (Last author)
Diffuse Glioneuronal tumour with Oligodendroglioma-like features and Nuclear Clusters (DGONC) - a molecularly-defined glioneuronal CNS tumour class displaying recurrent monosomy 14.
Neuropathology & applied neurobiology 46(5), 422-430 (2020) [10.1111/nan.12590]2020 BibTeX | EndNote: XML, Text | RIS

Pickles, J. C. ; Fairchild, A. R. ; Stone, T. J. ; Brownlee, L. ; Merve, A. ; Yasin, S. A. ; Avery, A. ; Ahmed, S. W. ; Ogunbiyi, O. ; Gonzalez Zapata, J. ; Peary, A. F. ; Edwards, M. ; Wilkhu, L. ; Dryden, C. ; Ladon, D. ; Kristiansen, M. ; Rowe, C. ; Kurian, K. M. ; Nicoll, J. A. R. ; Mitchell, C. ; Bloom, T. ; Hilton, D. A. ; Al-Sarraj, S. ; Doey, L. ; Johns, P. N. ; Bridges, L. R. ; Chakrabarty, A. ; Ismail, A. ; Rathi, N. ; Syed, K. ; Lammie, G. A. ; Limback-Stanic, C. ; Smith, C. ; Torgersen, A. ; Rae, F. ; Hill, R. M. ; Clifford, S. C. ; Grabovska, Y. ; Williamson, D. ; Clarke, M. ; Jones, C. ; Capper, D. ; Sill, M. ; von Deimling, A. ; Pfister, S. M. ; Jones, D. T. W. ; Hargrave, D. ; Chalker, J. ; Jacques, T. S.
DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.
The lancet child & adolescent health 4(2), 121-130 (2020) [10.1016/S2352-4642(19)30342-6]2020 BibTeX | EndNote: XML, Text | RIS

Braczynski, A. K. ; Capper, D. ; Jones, D. T. W. ; Schittenhelm, J. ; Stichel, D. ; von Deimling, A. ; Harter, P. ; Mittelbronn, M.
High density DNA methylation array is a reliable alternative for PCR-based analysis of the MGMT promoter methylation status in glioblastoma.
Pathology, research and practice 216(1), 152728 (2020) [10.1016/j.prp.2019.152728]2020 BibTeX | EndNote: XML, Text | RIS

Pfaff, E. (First author) ; Aichmüller, C. ; Sill, M. ; Stichel, D. ; Snuderl, M. ; Karajannis, M. A. ; Schuhmann, M. U. ; Schittenhelm, J. ; Hasselblatt, M. ; Thomas, C. ; Korshunov, A. ; Rhizova, M. ; Wittmann, A. ; Kaufhold, A. ; Iskar, M. ; Ketteler, P. ; Lohmann, D. ; Orr, B. A. ; Ellison, D. W. ; von Hoff, K. ; Mynarek, M. ; Rutkowski, S. ; Sahm, F. ; von Deimling, A. ; Lichter, P. ; Kool, M. ; Zapatka, M. ; Pfister, S. M. ; Jones, D. (Last author)
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.
Acta neuropathologica 139(2), 243-257 (2020) [10.1007/s00401-019-02101-0]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Chiang, J. ; Schrimpf, D. ; Stichel, D. ; Paramasivam, N. ; Sill, M. ; Gayden, T. ; Casalini, B. ; Reuss, D. E. ; Dalton, J. ; Pajtler, K. W. ; Hänggi, D. ; Herold-Mende, C. ; Rushing, E. ; Korshunov, A. ; Mawrin, C. ; Weller, M. ; Schlesner, M. ; Wick, W. ; Jabado, N. ; Jones, D. T. W. ; Pfister, S. M. ; von Deimling, A. ; Ellison, D. W. ; Sahm, F. (Last author)
YAP1-fusions in pediatric NF2-wildtype meningioma.
Acta neuropathologica 139(1), 215-218 (2020) [10.1007/s00401-019-02095-9]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Hasselblatt, M. ; Hagel, C. ; Staszewski, O. ; Hench, J. ; Frank, S. ; Brandner, S. ; Korshunov, A. ; Wick, W. ; Pfister, S. M. ; Reifenberger, G. ; von Deimling, A. ; Sahm, F. (Last author) ; Jones, D. (Last author)
Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation.
Acta neuropathologica 139(2), 403-406 (2020) [10.1007/s00401-019-02097-7]2020 BibTeX | EndNote: XML, Text | RIS

Wefers, A. (First author) ; Stichel, D. ; Schrimpf, D. ; et al
Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
Acta neuropathologica 139(1), 193-209 (2020) [10.1007/s00401-019-02078-w]2020 BibTeX | EndNote: XML, Text | RIS

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