Cookie Settings

We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .

Essential

These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name Webedition CMS
Purpose This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name econda
Purpose Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.
Statistics

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name econda
Purpose Statistics
External media

Content from external media platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name YouTube
Purpose Show YouTube content
Name Twitter
Purpose activate Twitter Feeds

Small Animal Imaging Center

Dr. Manfred Jugold

The Small Animal Imaging Center supports users in the application of numerous radiological methods such as ultrasound, optical imaging, µPET, µCT, µSPECT and MRT measurements to collect and quantify morphological and functional data in vivo.


Multimodal Imaging (in vivo)

•  creation of illustrations
•  tumor staging
•  Screening for metastases
•  Intraindividual monitoring of therapy progress

 

 

 


Measurement of quantitative data (in vivo)

  • blood volume
  • vascular permeability
  • perfusion
  • oxygen saturation
  • bone density (HU)
  • volumetric measurement
  • morphology
  • metabolic activity
  • pharmacokinetics


Further services

  • Project planning of animal studies
  • feasibility studies
  • Evaluation of raw data
  • scientific evaluation of the data
  • data storage
  • Support writing applications and publications


Small Animal Imaging Center

Modern non-invasive small animal imaging for comprehensive evaluation of pathologies and therapy monitoring in vivo.

Under the direction of Dr. Manfred Jugold, the Core Facility Small Animal Imaging offers a comprehensive service for the non-invasive characterization of small animal pathologies for DKFZ internal groups only.

The radiological possibilities in todays small animal imaging techniques are able to obtain a multitude of significant data and meaningful images from living animals. By means of most animal-friendly procedures, entire therapy processes can be documented in vivo during the course of the study.

Through the modern methods of non-invasive small animal imaging it is often possible to strongly reduce the number of animals needed to achieve a study goal. At the same time, the significance of the results can be maintained or even increased and additional parameters can be examined. In this way, decisive contributions can be made to research on animal models, from simple documentation and the recording of pathologies, through therapy monitoring to the measurement of quantitative and functional tissue parameters. Furthermore, results, e. g. for publications or patent applications can be enhanced by meaningful images.

Compared to conventional invasive or approximate methods, small animal imaging offers decisive advantages:

  • Recording of quantitative volumetric data
  • Monitoring of intraindividual therapy courses
  • Recording of functional tissue parameters
  • Increasing the significance of the results
  • Imaging of finest morphologic structures
  • Rationalisation of animal numbers


Furthermore, we offer support in the design of animal studies, the selection of suitable modalities, the processing of the raw data,as well as the evaluation/interpretation of the results and the publication of the study.


Available modalities and equipment:
MRI: Icon, Bruker

  • 1Tesla small animal scanner

Three-modality small animal scanner: Inveon, Siemens

  • μCT
  • μPET
  • μSPECT

Photoacoustic Imaging: Fujifilm, VisualSonics

  • LAZR-Photoacoustic-Imaging-System
    Wavelength range: 680 - 970 nm and 1200 - 2000 nm

Optical imaging: PerkinElmer

  • IVIS Lumina III, In Vivo Imaging System
    Bioluminescence Imaging
    Fluorescence Imaging

Ultrasound: Fujifilm, VisualSonics

  • Vevo 3100™
    Transducer mouse 13-24 MHz
    Transducer rat 22-55 MHz

Contact

Core Facility Small Animal Imaging Center
Dr. Manfred Jugold
Telefon: 4455
E-Mail: kleintierbildgebung@dkfz.de

to top
powered by webEdition CMS