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- Advancement of clinical proteomics for systems medicine
- Bridging from the single cell to the cell population – Epo-induced cellular responses and erythroleukemia
- Deciphering tumor microenvironment interactions determining lung cancer development
- Mechanisms controlling the compensation of liver injury and towards model-based biomarkers for early detection of liver cancer
- Application of dynamic pathway modelling for personalized medicine
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Characterization and regulation of NCR and NKG2D ligands in cancer
Number of publications: 5
Israeli Partner: A. Porgador, Ben-Gurion Univ.
German Partner: A. Cerwenka, DKFZ
Publications
| Publication |
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| Publication |
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Brusilovsky, M., Cordoba, M., Rosental, B., Hershkovitz, O., Andrake, M. D., Pecherskaya, A., Einarson, M. B., Zhou, Y., Braiman, A., Campbell, K. S., Porgador, A.
Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses 191 (10), J Immunol, 5256-67, 2013 |
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Fiegler, N., Textor, S., Arnold, A., Rolle, A., Oehme, I., Breuhahn, K., Moldenhauer, G., Witzens-Harig, M., Cerwenka, A.
Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells 122 (5), Blood, 684-93, 2013 |
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Ni, J., Miller, M., Stojanovic, A., Garbi, N., Cerwenka, A.
Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors 209 (13), J Exp Med, 2351-65, 2012 |
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Rosental, B., Brusilovsky, M., Hadad, U., Oz, D., Appel, M. Y., Afergan, F., Yossef, R., Rosenberg, L. A., Aharoni, A., Cerwenka, A., Campbell, K. S., Braiman, A., Porgador, A.
Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44 187 (11), J Immunol, 5693-702, 2011 |
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Textor, S., Fiegler, N., Arnold, A., Porgador, A., Hofmann, T. G., Cerwenka, A.
Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2 71 (18), Cancer Res, 5998-6009, 2011 |