Research
- Research Topics
- Cell Biology and Tumor Biology
- Stem Cells and Cancer
- Inflammatory Stress in Stem Cells
- Experimental Hematology
- Molecular Embryology
- Signal Transduction and Growth Control
- Epigenetics
- Redox Regulation
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- Molecular Leukemogenesis
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- Neuronal Signaling and Morphogenesis
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- Cell Morphogenesis and Signal Transduction
- Tumour Metabolism and Microenvironment
- Helmholtz Professorship Cell Biology
- Functional and Structural Genomics
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- Molecular Genetics
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- Cancer Genome Research
- Chromatin Networks
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- RNA Biology and Cancer
- Systems Biology of Signal Transduction
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- Mechanisms of Leukemogenesis
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- DNA Vectors
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- Cell Biology and Tumor Biology
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- WHO Collaborating Centers
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Publications
Selected References:
Niebler M, Qian X, Höfler D, Kogosov V, Kaewprag J, Kaufmann AM, Ly R, Böhmer G, Zawatzky R, Rösl F, Rincon-Orozco B. (2013)
Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53.
PLoS Pathog. 9: e1003536.
Raykov Z, Grekova SP, Hörlein R, Leuchs B, Giese T, Giese NA, Rommelaere J, Zawatzky R, Daeffler L. (2013)
TLR-9 contributes to the antiviral innate immune sensing of rodent parvoviruses MVMp and H-1PV by normal human immune cells.
PLoS One. 8 :e55086. doi: 10.1371/journal.pone.0055086. Epub 2013 Jan 29.
Grekova SP, Raykov Z, Zawatzky R, Rommelaere J, Koch U. (2012).Activation of a glioma-specific immune response by oncolytic parvovirus Minute Virus of Mice infection.
Cancer Gene Ther 19:468-75.
Schwandt T, Schumak B, Gielen GH, Jüngerkes F, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Kalff JC, Weber O, Kirschning C, Coch C, Kalinke U, Wenzel J, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A. E. (2011) Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. EMBO J;31:201-213
Ksienzyk A, Neumann B, Nandakumar R, Finsterbusch K, Grashoff M, Zawatzky R, Bernhardt G, Hauser H, Kröger A (2011). IRF-1 expression is essential for natural killer cells to suppress metastasis. Cancer Res.71:6410-6418
Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA (2010). Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity. Gastroenterology 138:336-346
Grekova S, Zawatzky R, Hörlein R, Cziepluch C, Mincberg M, Davis C, Rommelaere J, Daeffler L. (2010). Activation of an antiviral response in normal but not transformed mouse cells: a new determinant of minute virus of mice oncotropism. J Virol. 84:516-531
Wilden H, Fournier P, Zawatzky R, Schirrmacher V (2009). Expression of RIG-I, IRF3, IFN-beta and IRF7 determines resistance or susceptibility of cells to infection by Newcastle Disease Virus.
Int J Oncol. 34:971-982
Parcina M, Wendt C, Goetz F, Zawatzky R, Zähringer U, Heeg K, Bekeredjian-Ding I (2008). Staphylococcus aureus-induced plasmacytoid dendritic cell activation is based on an IgG-mediated memory response. J Immunol.181:3823-3833
Zschiedrich I, Hardeland U, Krones-Herzig A, Berriel Diaz M, Vegiopoulos A, Müggenburg J, Sombroek D, Hofmann TG, Zawatzky R, Yu X, Gretz N, Christian M, White R, Parker MG, Herzig S. (2008). Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression.
Blood 112:264-276