Post-transcriptional regulation of viral gene expression

Bryan R. Cullen - Duke University

 July 14, 2016
Main Auditorium
Host: M. Loechelt

Short Bio: Bryan R. Cullen obtained a B.Sc. in Biochemistry from Warwick University in the UK and a M.Sc. in Virology from the University of Birmingham before moving to the USA, where he obtained a Ph.D. in Microbiology from Rutgers University. In 1987, he was recruited to Duke University Medical Center as a Howard Hughes Medical Institute Investigator. He currently holds a James B. Duke Professorship in the Department of Molecular Genetics and Microbiology and serves as Director of the Center for Virology at Duke. Dr. Cullen’s research interests have historically revolved around the use of viruses as genetic tools to understand aspects of the biology of the eukaryotic cell, focusing particularly on RNA-sequence mediated gene regulation. Currently, his laboratory is studying the biogenesis and function of microRNAs, in particular virus-encoded microRNAs, as well as the use of CRISPR/Cas for the specific editing of viral DNA genomes. He is also interested in the role of post-transcriptional RNA modifications in regulating viral replication. Dr. Cullen has published over 300 research papers and is on the editorial board of several prominent journals.

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