Selected publications

Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, Lewinger JP, Witte JS, Chen G, Bull S, Hung RJ. Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2013, 132(5): 579-89.

Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, Gu L, Muley T, Meister M, Dienemann H, Plass C, Risch A. Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4. Oncogene 2013, 32(28): 3329-38.

Timofeeva MN, ... Risch A, ... Landi MT; for TRICL Research Team. Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet. 2012, 21(22): 4980-95.

Hartz SM, ... Risch A, ... Bierut LJ. Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers. Arch Gen Psychiatry 2012, 69(8): 854-60.

Campa D, Müller P, Edler L, Knoefel L, Barale R, Heussel CP, Thomas M, Canzian F, Risch A. A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis. Int J Cancer 2012, 131(12): 2920-8.

Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG. Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet. 2011 43:513-518.

Knöfel L.F, Werle-Schneider G., Dally H., Müller P.J., Jäger B., Edler L. , Bartsch H., Tuengerthal S., Heussel C.P., Thomas M., Risch A. Influence of polymorphisms in apoptotic genes on chemotherapy response and outcome in lung cancer patients. Journal of Thoracic Oncology 2011 6:183-189.

Landi MT, Chatterjee N, Caporaso NE, Rotunno M, Albanes D, Thun M, Wheeler W, Rosenberger A, Bickeböller H, Risch A, Wang Y, Gaborieau V, Thorgeirsson T, Gudbjartsson D, Sulem P, Spitz MR, Wichmann HE, Rafnar T, Stefansson K, Houlston RS, Brennan P. GPC5 rs2352028 variant and risk of lung cancer in never smokers. Lancet Oncology 2010 11:714-716.

Truong T., Hung R. J., Amos C. I., Wu X., Bickeböller H., Rosenberger A., Sauter W., Illig T., Wichmann H.-E., Risch A., Dienemann H., Kaaks R., Yang P., Jiang R., Wiencke J. K., Wrensch M., Hansen H., Kelsey K. T., Matsuo K., Tajima K., Schwartz A. G., Wenzlaff A., Seow A., Ying C., Staratschek-Jox A., Nürnberg P., Stoelben E., Wolf J., Lazarus P., Muscat J. E., Gallagher C., Zienolddiny S., Haugen A., van der Heijden H. F. M., Kiemeney L. A., Isla D., Mayordomo J. I., Rafnar T., Stefansson K., Zhang Z.-F., Chang S.-C., Kim J. H., Hong Y.-C., Duell E. J., Andrew A. S., Lejbkowicz F., Rennert G., Müller H., Brenner H., Le Marchand L., Benhamou S., Bouchardy C., Teare M. D., Xue Xi., McLaughlin J., Liu G., McKay J. D., Brennan P., Spitz M. Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A Pooled Analysis From the International Lung Cancer Consortium. J Natl Cancer Inst. 2010 102:959-971.

Timofeeva M, Kropp S, Sauter W, Beckmann L, Rosenberger A, Illig T, Jäger B, Mittelstrass K, Dienemann H, Bartsch H, Bickeböller H, Chang-Claude J, Risch A, Wichmann HE; The LUCY‐Consortium. Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer. Int J Cancer 2010 127(7):1547-1561.

Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, Thun M, Diver R, Oken M, Virtamo J, Albanes D, Wang Z, Burdette L, Doheny KF, Pugh EW, Laurie C, Brennan P, Hung R, Gaborieau V, McKay JD, Lathrop M, McLaughlin J, Wang Y, Tsao MS, Spitz MR, Wang Y, Krokan H, Vatten L, Skorpen F, Arnesen E, Benhamou S, Bouchard C, Metsapalu A, Vooder T, Nelis M, Välk K, Field JK, Chen C, Goodman G, Sulem P, Thorleifsson G, Rafnar T, Eisen T, Sauter W, Rosenberger A, Bickeböller H, Risch A, Chang-Claude J, Wichmann HE, Stefansson K, Houlston R, Amos CI, Fraumeni JF Jr, Savage SA, Bertazzi PA, Tucker MA, Chanock S, Caporaso NE. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet. 2009;85(5):679-91.

Scherf DB, Dally H, Müller P, Werle-Schneider G, Jäger B, Edler L, Tuengerthal S, Fischer JR, Drings P, Bartsch H, Risch A. SNPs in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis. Eur Respir J. 2009; 35(2):381-90.

Timofeeva M, Kropp S, Sauter W, Beckmann L, Rosenberger A, Illig T, Jäger B, Mittelstrass K, Dienemann H; The LUCY-Consortium, Bartsch H, Bickeböller H, Chang-Claude J, Risch A, Wichmann HE. CYP 450 polymorphisms as risk factors for early onset lung cancer: gender specific differences. 2009; 30(7): 1161-9.

Timofeeva M, Jäger B, Rosenberger A, Sauter W, Wichmann HE; KORA Study Group, Bickeböller H, Risch A. A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers. Clin Biochem. 2009; 42(6): 500-9.

Müller PJ, Dally H, Klappenecker CN, Edler L, Jäger B, Gerst M, Spiegelhalder B, Tuengerthal S, Fischer JR, Drings P, Bartsch H, Risch A. Polymorphisms in ABCG2, ABCC3 and CNT1 genes and their possible impact on chemotherapy outcome of lung cancer patients. Int J Cancer 2009; 124(7): 1669-74.

Sauter W, Rosenberger A, Beckmann L, Kropp S, Mittelstrass K, Timofeeva M, Wölke G, Steinwachs A, Scheiner D, Meese E, Sybrecht G, Kronenberg F, Dienemann H; The LUCY-Consortium, Chang-Claude J, Illig T, Wichmann HE, Bickeböller H, Risch A. Matrix Metalloproteinase 1 (MMP1) Is Associated with Early-Onset Lung Cancer. Cancer Epidemiol Biomarkers Prev. 2008; 17(5): 1127-1135.

Mittelstrass K, Sauter W, Rosenberger A, Illig T, Timofeeva M, Klopp N, Dienemann H, Meese E, Sybrecht G, Woelke G, Cebulla M, Degen M, Morr H, Drings P, Groeschel A, Kreymborg KG, Haeussinger K, Hoeffken G, Schmidt C, Jilge B, Schmidt W, Ko YD, Taeuscher D, Chang-Claude J, Wichmann HE, Bickeboeller H, Risch A. Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene. BMC Cancer 2008; 8: 113.

Risch A, Plass C. Lung cancer epigenetics and genetics. Int J Cancer 2008; 123(1): 1-7.

Bartsch H, Dally H, Popanda O, Risch A, Schmezer P. Genetic risk profiles for cancer susceptibility and therapy response. Recent Results Cancer Res. 2007; 174:19-36. Review.

Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MW, Pooley KA, Scollen S, Baynes C, Ponder BA, Chanock S, Lissowska J, Brinton L, Peplonska B, Southey MC, Hopper JL, McCredie MR, Giles GG, Fletcher O, Johnson N, dos Santos Silva I, Gibson L, Bojesen SE, Nordestgaard BG, Axelsson CK, Torres D, Hamann U, Justenhoven C, Brauch H, Chang-Claude J, Kropp S, Risch A, Wang-Gohrke S, Schürmann P, Bogdanova N, Dörk T, Fagerholm R, Aaltonen K, Blomqvist C, Nevanlinna H, Seal S, Renwick A, Stratton MR, Rahman N, Sangrajrang S, Hughes D, Odefrey F, Brennan P, Spurdle AB, Chenevix-Trench G; Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer, Beesley J, Mannermaa A, Hartikainen J, Kataja V, Kosma VM, Couch FJ, Olson JE, Goode EL, Broeks A, Schmidt MK, Hogervorst FB, Van't Veer LJ, Kang D, Yoo KY, Noh DY, Ahn SH, Wedrén S, Hall P, Low YL, Liu J, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Sigurdson AJ, Stredrick DL, Alexander BH, Struewing JP, Pharoah PD, Easton DF; Breast Cancer Association Consortium. A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet. 2007; 39(3): 352-8.

Complete publication list

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