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Publications: Papers 1978 - 1989

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  1. J. Langowski, K. Henco, D. Riesner, H.L. Sänger:
    Common structural features of different viroids: serial arrangement of double helical sections and internal loops.
    Nucl. Acids Res. (1978) 5, 1589-1610 [PDF]


  1. Tóth, K. (1979)
    Light scattering of bacterium and virus solutions. (in Hungarian)
    Study presented at the competition of Young Hungarian Biophysicists, Budapest


  1. Langowski, J., Goppelt, M., Maaß, G. & Pingoud, A. M. (1980).
    Investigations on the mechanism of the cleavage reaction of the restriction endonuclease EcoRI.
    Hoppe-Seylers Zeitschrift für Physiologische Chemie 361, 293.
  2. J. Langowski, A. Pingoud, M. Goppelt, G. Maaß:
    Inhibition of EcoR1 by polynucleotides. A characterization of the non-specific binding of the enzyme to DNA.
    Nucl. Acids Res. (1980) 8, 4727-4736 [PDF]
  3. G. Maaß, J. Langowski, M. Goppelt, A. Pingoud:
    DNA binding by restriction endonuclease EcoR1,
    in: Biological implications of protein-nucleic acid interactions, ed. J. Augustyniak, (1980) Adam Mickiewicz Univ. Press, Poznan, pp. 558-565
  4. G. Maaß, J. Langowski, A. Pingoud, C. Urbanke, M. Goppelt:
    The recognition of specific DNA sequences by restriction endonucleases. Steady state and fast kinetic studies on the cleavage of superhelical DNA by EcoR1.
    Stud. Biophys. (1980) 81, 119-120
  5. Tóth, K. , Fekete, A. (1980)
    Effect of microenvironment on the structure of bacteriophage solutions. (Light scattering study).
    Acta Biochim. Biophys. Acad. Sci. Hung. 15, 127


  1. D. Shore, J. Langowski, R.L. Baldwin:
    DNA flexibility studied by covalent closure of short DNA fragments into circles.
    Proc. Nat. Acad. Sci. USA (1981) 78, 4833-4837 [PDF]
  2. J. Langowski, C. Urbanke, A. Pingoud, G. Maaß:
    Transient cleavage kinetics of the EcoR1 restriction endonuclease measured in a pulsed quench-flow apparatus: enzyme concentration-dependent activity change.
    Nucl. Acids Res. (1981) 9, 3483-3490 [PDF]
  3. M. Goppelt, J. Langowski, A. Pingoud, W. Haupt, C. Urbanke, H. Mayer, G. Maaß:
    The effect of several nucleic acid binding drugs on the cleavage of d(GGAATTCC) and pBR322 by the EcoR1 restriction endonuclease.
    Nucl. Acids Res. (1981) 9, 6115-6127
  4. Alves, J., Pingoud, A., Langowski, J. & Maass, G. (1981).
    The endonucleolytic reaction catalyzed by the EcoRI restriction enzyme is inhibited when the enzyme is in excess over substrate.
    Biophys. Struct. Mech. 7, 247-248.


  1. J. Alves, A. Pingoud, J. Langowski, C. Urbanke, G. Maaß:
    Two identical subunits of the EcoR1 restriction endonuclease co-operate in the binding and cleavage of the palindromic substrate.
    Eur. J. Biochem. (1982) 124, 139-142
  2. C. Urbanke, J. Langowski, E. Schuppe:
    Microprocessor controlled quenched flow apparatus for the study of fast chemical reactions.
    Z. Anal. Chem. (1982) 311, 364-365
  3. J. Langowski, C. Urbanke:
    A continuous fluorimetric assay for the EcoR1 restriction endonuclease.
    Z. Anal. Chem. (1982) 311, 367


  1. J. Langowski, J. Alves, A. Pingoud, G. Maaß:
    Does the specific recognition of DNA by the restriction endonuclease EcoR1 involve a linear diffusion step? Investigation of the processivity of the EcoR1 endonuclease.
    Nucl. Acids Res. (1983) 11, 501-513


  1. J. Alves, A. Pingoud, W. Haupt, J. Langowski, G. Maaß, C. Wolf:
    The influence of sequences adjacent to the recognition site on the cleavage of oligodeoxynucleotides and plasmid DNAs by the EcoR1 endonuclease.
    Eur. J. Biochem. (1984) 140, 83-92
  2. J. Langowski, C. Urbanke, E. Schuppe:
    Construction of a microprocessor controlled pulsed quench-flow apparatus for the study of fast chemical and biochemical reactions.
    Anal. Biochem. (1984) 142, 91-97


  1. Langowski, J. & Giesen, U. (1985).
    Dynamics of superhelical DNA studied by photon-correlation spectroscopy.
    Biol. Chem. Hoppe-Seyler 366, 818-818.
  2. J. Langowski, B.S. Fujimoto, D. Wemmer, A.S. Benight, G. Drobny, J.H. Shibata, J.M. Schurr:
    Deformational dynamics and NMR relaxation of supercoiled DNAs.
    Biopolymers (1985) 24, 1023-1056
  3. Schurr, J. M., Shibata, J. H., Wilcoxon, J., Benight, A. S., Langowski, J., Thomas, J. C. & Fujimoto, B. S. (1985).
    Evidence For 2 Different Global Secondary Structures of Supercoiled Dnas and Buffer-Induced Switching.
    Biophys. J. 47, A16.
  4. J. Langowski, A.S. Benight, B.S. Fujimoto, J.M. Schurr, U. Schomburg:
    Change of conformation and internal dynamics of supercoiled DNA upon binding of E.coli single strand binding protein.
    Biochemistry (1985) 24, 4022-4028
  5. F.U. Gast, J. Langowski, A. Pingoud:
    Product analysis of in vitro ribosomal protein synthesis for the assessment of kinetic parameters.
    Anal. Biochem. (1985) 147, 364-368


  1. J. Langowski, U. Giesen, Chr. Lehmann:
    Dynamics of superhelical DNA studied by photon correlation spectroscopy.
    Biophys. Chem. (1986) 25, 191-200


  1. Wu, P. G., Schurr, J. M., Benight, A. S., Langowski, J. & Fujimoto, B. S. (1987).
    Theory of dynamic light-scattering from rigid double-spirals - a model for supercoiled DNA.
    Biophys. J. 51, A504.
  2. J. Langowski:
    Salt effects on internal motions of superhelical and linear DNA. Dynamic light scattering studies.
    Biophys. Chem. (1987) 27, 263-271
  3. A.S. Benight, J. Langowski, P.-G. Wu, J. Wilcoxon, J.H. Shibata, B.S. Fujimoto, N.S. Ribeiro, J.M. Schurr:
    Structure and Dynamics of Supercoiled DNAs,
    in: Laser Scattering Spectroscopy of Biological Objects, eds. J. Stepanek, P. Anzenbacher, B. Sedlacek, pp. 407-422 (Elsevier, Amsterdam-Oxford-New York-Tokyo 1987)
  4. 1988





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