1. Ward, A., Balwierz, A., Zhang, J. D., Kublbeck, M., Pawitan, Y., Hielscher, T., Wiemann, S., Sahin, O., (2012) Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. Oncogene, :
   link to pubmed
   
   
2. Walde, S., Thakar, K., Hutten, S., Spillner, C., Nath, A., Rothbauer, U., Wiemann, S., Kehlenbach, R. H., (2012) The nucleoporin Nup358/RanBP2 promotes nuclear import in a cargo- and transport receptor-specific manner. Traffic, 13:218-33
   link to pubmed
   
   
3. Ummanni, R., Barreto, F., Venz, S., Scharf, C., Barett, C., Mannsperger, H. A., Brase, J. C., Kuner, R., Schlomm, T., Sauter, G., Sultmann, H., Korf, U., Bokemeyer, C., Walther, R., Brummendorf, T. H., Balabanov, S., (2012) Peroxiredoxins 3 and 4 are overexpressed in prostate cancer tissue and affect the proliferation of prostate cancer cells in vitro. J Proteome Res, 11:2452-66
   link to pubmed
   
   
4. Uhlmann, S., Mannsperger, H., Zhang, J. D., Horvat, E. A., Schmidt, C., Kublbeck, M., Henjes, F., Ward, A., Tschulena, U., Zweig, K., Korf, U., Wiemann, S., Sahin, O., (2012) Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer. Mol Syst Biol, 8:570
   link to pubmed
   
   
5. Shamu, C. E., Wiemann, S., Boutros, M., (2012) On target: a public repository for large-scale RNAi experiments. Nat Cell Biol, 14:115
   link to pubmed
   
   
6. Malinowsky, K., Wolff, C., Berg, D., Schuster, T., Walch, A., Bronger, H., Mannsperger, H., Schmidt, C., Korf, U., Hofler, H., Becker, K. F., (2012) uPA and PAI-1-Related Signaling Pathways Differ between Primary Breast Cancers and Lymph Node Metastases. Transl Oncol, 5:98-104
   link to pubmed
   
   
7. Lisauskas, T., Matula, P., Claas, C., Reusing, S., Wiemann, S., Erfle, H., Lehmann, L., Fischer, P., Eils, R., Rohr, K., Storrie, B., Starkuviene, V., (2012) Live-cell assays to identify regulators of ER-to-Golgi trafficking. Traffic, 13:416-32
   link to pubmed
   
   
8. Leblond, C. S., Heinrich, J., Delorme, R., Proepper, C., Betancur, C., Huguet, G., Konyukh, M., Chaste, P., Ey, E., Rastam, M., Anckarsater, H., Nygren, G., Gillberg, I. C., Melke, J., Toro, R., Regnault, B., Fauchereau, F., Mercati, O., Lemiere, N., Skuse, D., Poot, M., Holt, R., Monaco, A. P., Jarvela, I., Kantojarvi, K., Vanhala, R., Curran, S., Collier, D. A., Bolton, P., Chiocchetti, A., Klauck, S. M., Poustka, F., Freitag, C. M., Waltes, R., Kopp, M., Duketis, E., Bacchelli, E., Minopoli, F., Ruta, L., Battaglia, A., Mazzone, L., Maestrini, E., Sequeira, A. F., Oliveira, B., Vicente, A., Oliveira, G., Pinto, D., Scherer, S. W., Zelenika, D., Delepine, M., Lathrop, M., Bonneau, D., Guinchat, V., Devillard, F., Assouline, B., Mouren, M. C., Leboyer, M., Gillberg, C., Boeckers, T. M., Bourgeron, T., (2012) Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet, 8:e1002521
   link to pubmed
   
   
9. Jurmeister, S., Baumann, M., Balwierz, A., Keklikoglou, I., Ward, A., Uhlmann, S., Zhang, J. D., Wiemann, S., Sahin, O., (2012) MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Mol Cell Biol, 32:633-51
   link to pubmed
   
   
10. Casey, J. P., Magalhaes, T., Conroy, J. M., Regan, R., Shah, N., Anney, R., Shields, D. C., Abrahams, B. S., Almeida, J., Bacchelli, E., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bolton, P. F., Bourgeron, T., Brennan, S., Cali, P., Correia, C., Corsello, C., Coutanche, M., Dawson, G., de Jonge, M., Delorme, R., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B. A., Folstein, S. E., Foley, S., Fombonne, E., Freitag, C. M., Gilbert, J., Gillberg, C., Glessner, J. T., Green, J., Guter, S. J., Hakonarson, H., Holt, R., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S. M., Kolevzon, A., Lamb, J. A., Leboyer, M., Le Couteur, A., Leventhal, B. L., Lord, C., Lund, S. C., Maestrini, E., Mantoulan, C., Marshall, C. R., McConachie, H., McDougle, C. J., McGrath, J., McMahon, W. M., Merikangas, A., Miller, J., Minopoli, F., Mirza, G. K., Munson, J., Nelson, S. F., Nygren, G., Oliveira, G., Pagnamenta, A. T., Papanikolaou, K., Parr, J. R., Parrini, B., Pickles, A., Pinto, D., Piven, J., Posey, D. J., Poustka, A., Poustka, F., Ragoussis, J., Roge, B., Rutter, M. L., Sequeira, A. F., Soorya, L., Sousa, I., Sykes, N., Stoppioni, V., Tancredi, R., Tauber, M., Thompson, A. P., Thomson, S., Tsiantis, J., Van Engeland, H., Vincent, J. B., Volkmar, F., Vorstman, J. A., Wallace, S., Wang, K., Wassink, T. H., White, K., Wing, K., Wittemeyer, K., Yaspan, B. L., Zwaigenbaum, L., Betancur, C., Buxbaum, J. D., Cantor, R. M., Cook, E. H., Coon, H., Cuccaro, M. L., Geschwind, D. H., Haines, J. L., Hallmayer, J., Monaco, A. P., Nurnberger, J. I., Jr., Pericak-Vance, M. A., Schellenberg, G. D., Scherer, S. W., Sutcliffe, J. S., Szatmari, P., Vieland, V. J., Wijsman, E. M., Green, A., Gill, M., Gallagher, L., Vicente, A., Ennis, S., (2012) A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Hum Genet, 131:565-79
    link to pubmed
    
    
11. Zhang, J. D., Koerner, C., Bechtel, S., Bender, C., Keklikoglou, I., Schmidt, C., Irsigler, A., Ernst, U., Sahin, O., Wiemann, S., Tschulena, U., (2011) Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PLoS One, 6:e22176
    link to pubmed
    
    
12. Wittig-Blaich, S. M., Kacprzyk, L. A., Eismann, T., Bewerunge-Hudler, M., Kruse, P., Winkler, E., Strauss, W. S., Hibst, R., Steiner, R., Schrader, M., Mertens, D., Sultmann, H., Wittig, R., (2011) Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells. Neoplasia, 13:579-89
    link to pubmed
    
    
13. Warth, A., Muley, T., Meister, M., Herpel, E., Pathil, A., Hoffmann, H., Schnabel, P. A., Bender, C., Buness, A., Schirmacher, P., Kuner, R., (2011) Loss of aquaporin-4 expression and putative function in non-small cell lung cancer. BMC Cancer, 11:161
    link to pubmed
    
    
14. Ummanni, R., Mundt, F., Pospisil, H., Venz, S., Scharf, C., Barett, C., Falth, M., Kollermann, J., Walther, R., Schlomm, T., Sauter, G., Bokemeyer, C., Sultmann, H., Schuppert, A., Brummendorf, T. H., Balabanov, S., (2011) Identification of clinically relevant protein targets in prostate cancer with 2D-DIGE coupled mass spectrometry and systems biology network platform. PLoS One, 6:e16833
    link to pubmed
    
    
15. Ummanni, R., Jost, E., Braig, M., Lohmann, F., Mundt, F., Barett, C., Schlomm, T., Sauter, G., Senff, T., Bokemeyer, C., Sultmann, H., Meyer-Schwesinger, C., Brummendorf, T. H., Balabanov, S., (2011) Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation. Mol Cancer, 10:129
    link to pubmed
    
    
16. Tschulena, U., Sanzenbacher, R., Muhlebach, M. D., Berger, A., Munch, J., Schindler, M., Kirchhoff, F., Plesker, R., Coulibaly, C., Panitz, S., Prufer, S., Muckenfuss, H., Hamdorf, M., Schweizer, M., Cichutek, K., Flory, E., (2011) Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease. Retrovirology, 8:14
    link to pubmed
    
    
17. Sonntag, J., Mannsperger, H., Jocker, A., Korf, U., (2011) Microspot immunoassay-based analysis of plasma protein profiles for biomarker discovery strategies. Methods Mol Biol, 785:237-45
    link to pubmed
    
    
18. Schetelig, M. F., Gotschel, F., Viktorinova, I., Handler, A. M., Wimmer, E. A., (2011) Recombination technologies for enhanced transgene stability in bioengineered insects. Genetica, 139:71-8
    link to pubmed
    
    
19. Rupp, A. K., Rupp, C., Keller, S., Brase, J. C., Ehehalt, R., Fogel, M., Moldenhauer, G., Marme, F., Sultmann, H., Altevogt, P., (2011) Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage. Gynecol Oncol, 122:437-46
    link to pubmed
    
    
20. Minner, S., Enodien, M., Sirma, H., Luebke, A. M., Krohn, A., Mayer, P. S., Simon, R., Tennstedt, P., Muller, J., Scholz, L., Brase, J. C., Liu, A. Y., Schluter, H., Pantel, K., Schumacher, U., Bokemeyer, C., Steuber, T., Graefen, M., Sauter, G., Schlomm, T., (2011) ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res, 17:5878-88
    link to pubmed
    
    
21. Mannsperger, H., Uhlmann, S., Korf, U., Sahin, O., (2011) Utilization of RNAi to validate antibodies for reverse phase protein arrays. Methods Mol Biol, 785:45-54
    link to pubmed
    
    
22. Luckert, K., Gotschel, F., Sorger, P. K., Hecht, A., Joos, T. O., Potz, O., (2011) Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions. Mol Cell Proteomics, 10:M110 007377
    link to pubmed
    
    
23. Klauck, S. M., Poustka, L., Chiocchetti, A., (2011) [Genetics and animal modeling of autism spectrum disorders. New developments]. Nervenarzt, 82:553-62
    link to pubmed
    
    
24. Kerick, M., Isau, M., Timmermann, B., Sultmann, H., Herwig, R., Krobitsch, S., Schaefer, G., Verdorfer, I., Bartsch, G., Klocker, H., Lehrach, H., Schweiger, M. R., (2011) Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics, 4:68
    link to pubmed
    
    
25. Keklikoglou, I., Koerner, C., Schmidt, C., Zhang, J. D., Heckmann, D., Shavinskaya, A., Allgayer, H., Guckel, B., Fehm, T., Schneeweiss, A., Sahin, O., Wiemann, S., Tschulena, U., (2011) MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kappaB and TGF-beta signaling pathways. Oncogene, :
    link to pubmed
    
    
26. Johannes, M., Frohlich, H., Sultmann, H., Beissbarth, T., (2011) pathClass: an R-package for integration of pathway knowledge into support vector machines for biomarker discovery. Bioinformatics, 27:1442-3
    link to pubmed
    
    
27. Henjes, F., Gotschel, F., Jocker, A., Korf, U., (2011) Quantitative analysis of phosphoproteins using microspot immunoassays. Methods Mol Biol, 785:191-201
    link to pubmed
    
    
28. Hellwinkel, O. J., Asong, L. E., Rogmann, J. P., Sultmann, H., Wagner, C., Schlomm, T., Eichelberg, C., (2011) Transcription alterations of members of the ubiquitin-proteasome network in prostate carcinoma. Prostate Cancer Prostatic Dis, 14:38-45
    link to pubmed
    
    
29. Gade, S., Porzelius, C., Faelth, M., Brase, J. C., Wuttig, D., Kuner, R., Binder, H., Sueltmann, H., Beissbarth, T., (2011) Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer. BMC Bioinformatics, 12:488
    link to pubmed
    
    
30. Fussbroich, B., Wagener, N., Macher-Goeppinger, S., Benner, A., Falth, M., Sultmann, H., Holzer, A., Hoppe-Seyler, K., Hoppe-Seyler, F., (2011) EZH2 depletion blocks the proliferation of colon cancer cells. PLoS One, 6:e21651
    link to pubmed
    
    
31. El Debs, B. W., Tschulena, U., Griffiths, A. D., Merten, C. A., (2011) A competitive co-cultivation assay for cancer drug specificity evaluation. J Biomol Screen, 16:818-24
    link to pubmed
    
    
32. Curran, S., Bolton, P., Rozsnyai, K., Chiocchetti, A., Klauck, S. M., Duketis, E., Poustka, F., Schlitt, S., Freitag, C. M., Lee, I., Muglia, P., Poot, M., Staal, W., de Jonge, M. V., Ophoff, R. A., Lewis, C., Skuse, D., Mandy, W., Vassos, E., Fossdal, R., Magnusson, P., Hreidarsson, S., Saemundsen, E., Stefansson, H., Stefansson, K., Collier, D., (2011) No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 Gene and Autism Spectrum Disorder. Am J Med Genet B Neuropsychiatr Genet, :
    link to pubmed
    
    
33. Chiocchetti, A., Pakalapati, G., Duketis, E., Wiemann, S., Poustka, A., Poustka, F., Klauck, S. M., (2011) Mutation and expression analyses of the ribosomal protein gene RPL10 in an extended German sample of patients with autism spectrum disorder. Am J Med Genet A, 155A:1472-5
    link to pubmed
    
    
34. Chiocchetti, A., Klauck, S. M., (2011) [Genetic analyses for identifying molecular mechanisms in autism spectrum disorders]. Z Kinder Jugendpsychiatr Psychother, 39:101-11
    link to pubmed
    
    
35. Bu, H., Bormann, S., Schafer, G., Horninger, W., Massoner, P., Neeb, A., Lakshmanan, V. K., Maddalo, D., Nestl, A., Sultmann, H., Cato, A. C., Klocker, H., (2011) The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection. Prostate, 71:575-87
    link to pubmed
    
    
36. Brase, J. C., Mannsperger, H., Sultmann, H., Korf, U., (2011) Antibody-mediated signal amplification for reverse phase protein array-based protein quantification. Methods Mol Biol, 785:55-64
    link to pubmed
    
    
37. Brase, J. C., Johannes, M., Schlomm, T., Falth, M., Haese, A., Steuber, T., Beissbarth, T., Kuner, R., Sultmann, H., (2011) Circulating miRNAs are correlated with tumor progression in prostate cancer. Int J Cancer, 128:608-16
    link to pubmed
    
    
38. Brase, J. C., Johannes, M., Mannsperger, H., Falth, M., Metzger, J., Kacprzyk, L. A., Andrasiuk, T., Gade, S., Meister, M., Sirma, H., Sauter, G., Simon, R., Schlomm, T., Beissbarth, T., Korf, U., Kuner, R., Sultmann, H., (2011) TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-beta signaling. BMC Cancer, 11:507
    link to pubmed
    
    
39. Bender, C., Heyde, S., Henjes, F., Wiemann, S., Korf, U., Beissbarth, T., (2011) Inferring signalling networks from longitudinal data using sampling based approaches in the R-package 'ddepn'. BMC Bioinformatics, 12:291
    link to pubmed
    
    
40. Bai, S. W., Herrera-Abreu, M. T., Rohn, J. L., Racine, V., Tajadura, V., Suryavanshi, N., Bechtel, S., Wiemann, S., Baum, B., Ridley, A. J., (2011) Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol, 9:54
    link to pubmed
    
    
41. Anney, R. J., Kenny, E. M., O'Dushlaine, C., Yaspan, B. L., Parkhomenka, E., Buxbaum, J. D., Sutcliffe, J., Gill, M., Gallagher, L., Bailey, A. J., Fernandez, B. A., Szatmari, P., Scherer, S. W., Patterson, A., Marshall, C. R., Pinto, D., Vincent, J. B., Fombonne, E., Betancur, C., Delorme, R., Leboyer, M., Bourgeron, T., Mantoulan, C., Roge, B., Tauber, M., Freitag, C. M., Poustka, F., Duketis, E., Klauck, S. M., Poustka, A., Papanikolaou, K., Tsiantis, J., Anney, R., Bolshakova, N., Brennan, S., Hughes, G., McGrath, J., Merikangas, A., Ennis, S., Green, A., Casey, J. P., Conroy, J. M., Regan, R., Shah, N., Maestrini, E., Bacchelli, E., Minopoli, F., Stoppioni, V., Battaglia, A., Igliozzi, R., Parrini, B., Tancredi, R., Oliveira, G., Almeida, J., Duque, F., Vicente, A., Correia, C., Magalhaes, T. R., Gillberg, C., Nygren, G., Jonge, M. D., Van Engeland, H., Vorstman, J. A., Wittemeyer, K., Baird, G., Bolton, P. F., Rutter, M. L., Green, J., Lamb, J. A., Pickles, A., Parr, J. R., Couteur, A. L., Berney, T., McConachie, H., Wallace, S., Coutanche, M., Foley, S., White, K., Monaco, A. P., Holt, R., Farrar, P., Pagnamenta, A. T., Mirza, G. K., Ragoussis, J., Sousa, I., Sykes, N., Wing, K., Hallmayer, J., Cantor, R. M., Nelson, S. F., Geschwind, D. H., Abrahams, B. S., Volkmar, F., Pericak-Vance, M. A., Cuccaro, M. L., Gilbert, J., Cook, E. H., Guter, S. J., Jacob, S., Nurnberger Jr, J. I., McDougle, C. J., Posey, D. J., Lord, C., Corsello, C., Hus, V., Kolevzon, A., Soorya, L., Parkhomenko, E., Leventhal, B. L., Dawson, G., Vieland, V. J., Hakonarson, H., Glessner, J. T., Kim, C., Wang, K., Schellenberg, G. D., Devlin, B., Klei, L., Minshew, N., Sutcliffe, J. S., Haines, J. L., Lund, S. C., Thomson, S., Coon, H., Miller, J., McMahon, W. M., Munson, J., Estes, A., Wijsman, E. M., (2011) Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders. Eur J Hum Genet, :
    link to pubmed
    
    
42. Youns, M., Fu, Y. J., Zu, Y. G., Kramer, A., Konkimalla, V. B., Radlwimmer, B., Sultmann, H., Efferth, T., (2010) Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics. Naunyn Schmiedebergs Arch Pharmacol, 382:221-34
    link to pubmed
    
    
43. Will, R. D., Eden, M., Just, S., Hansen, A., Eder, A., Frank, D., Kuhn, C., Seeger, T. S., Oehl, U., Wiemann, S., Korn, B., Koegl, M., Rottbauer, W., Eschenhagen, T., Katus, H. A., Frey, N., (2010) Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing. Circ Res, 107:1253-64
    link to pubmed
    
    
44. Wilber, A., Tschulena, U., Hargrove, P. W., Kim, Y. S., Persons, D. A., Barbas, C. F., 3rd, Nienhuis, A. W., (2010) A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts. Blood, 115:3033-41
    link to pubmed
    
    
45. Uhlmann, S., Zhang, J. D., Schwager, A., Mannsperger, H., Riazalhosseini, Y., Burmester, S., Ward, A., Korf, U., Wiemann, S., Sahin, O., (2010) miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer. Oncogene, 29:4297-306
    link to pubmed
    
    
46. Sousa, I., Clark, T. G., Holt, R., Pagnamenta, A. T., Mulder, E. J., Minderaa, R. B., Bailey, A. J., Battaglia, A., Klauck, S. M., Poustka, F., Monaco, A. P., (2010) Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry. Mol Autism, 1:7
    link to pubmed
    
    
47. Rostamiani, K., Klauck, S. M., Heiss, N., Poustka, A., Khaleghi, M., Rosales, R., Metzenberg, A. B., (2010) Novel mutations of the DKC1 gene in individuals affected with dyskeratosis congenita. Blood Cells Mol Dis, 44:88
    link to pubmed
    
    
48. Pinto, D., Pagnamenta, A. T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., Almeida, J., Bacchelli, E., Bader, G. D., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bolte, S., Bolton, P. F., Bourgeron, T., Brennan, S., Brian, J., Bryson, S. E., Carson, A. R., Casallo, G., Casey, J., Chung, B. H., Cochrane, L., Corsello, C., Crawford, E. L., Crossett, A., Cytrynbaum, C., Dawson, G., de Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B. A., Folstein, S. E., Fombonne, E., Freitag, C. M., Gilbert, J., Gillberg, C., Glessner, J. T., Goldberg, J., Green, A., Green, J., Guter, S. J., Hakonarson, H., Heron, E. A., Hill, M., Holt, R., Howe, J. L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S. M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C. M., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B. L., Lionel, A. C., Liu, X. Q., Lord, C., Lotspeich, L., Lund, S. C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C. R., McConachie, H., McDougle, C. J., McGrath, J., McMahon, W. M., Merikangas, A., Migita, O., Minshew, N. J., Mirza, G. K., Munson, J., Nelson, S. F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J. R., Parrini, B., Paton, T., Pickles, A., Pilorge, M., Piven, J., Ponting, C. P., Posey, D. J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M. L., Bierut, L. J., Rice, J. P., Salt, J., Sansom, K., Sato, D., Segurado, R., Sequeira, A. F., Senman, L., Shah, N., Sheffield, V. C., Soorya, L., Sousa, I., Stein, O., Sykes, N., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A. P., Thomson, S., Tryfon, A., Tsiantis, J., Van Engeland, H., Vincent, J. B., Volkmar, F., Wallace, S., Wang, K., Wang, Z., Wassink, T. H., Webber, C., Weksberg, R., Wing, K., Wittemeyer, K., Wood, S., Wu, J., Yaspan, B. L., Zurawiecki, D., Zwaigenbaum, L., Buxbaum, J. D., Cantor, R. M., Cook, E. H., Coon, H., Cuccaro, M. L., Devlin, B., Ennis, S., Gallagher, L., Geschwind, D. H., Gill, M., Haines, J. L., Hallmayer, J., Miller, J., Monaco, A. P., Nurnberger, J. I., Jr., Paterson, A. D., Pericak-Vance, M. A., Schellenberg, G. D., Szatmari, P., Vicente, A. M., Vieland, V. J., Wijsman, E. M., Scherer, S. W., Sutcliffe, J. S., Betancur, C., (2010) Functional impact of global rare copy number variation in autism spectrum disorders. Nature, 466:368-72
    link to pubmed
    
    
49. Pagnamenta, A. T., Bacchelli, E., de Jonge, M. V., Mirza, G., Scerri, T. S., Minopoli, F., Chiocchetti, A., Ludwig, K. U., Hoffmann, P., Paracchini, S., Lowy, E., Harold, D. H., Chapman, J. A., Klauck, S. M., Poustka, F., Houben, R. H., Staal, W. G., Ophoff, R. A., O'Donovan, M. C., Williams, J., Nothen, M. M., Schulte-Korne, G., Deloukas, P., Ragoussis, J., Bailey, A. J., Maestrini, E., Monaco, A. P., (2010) Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry, 68:320-8
    link to pubmed
    
    
50. Noor, A., Whibley, A., Marshall, C. R., Gianakopoulos, P. J., Piton, A., Carson, A. R., Orlic-Milacic, M., Lionel, A. C., Sato, D., Pinto, D., Drmic, I., Noakes, C., Senman, L., Zhang, X., Mo, R., Gauthier, J., Crosbie, J., Pagnamenta, A. T., Munson, J., Estes, A. M., Fiebig, A., Franke, A., Schreiber, S., Stewart, A. F., Roberts, R., McPherson, R., Guter, S. J., Cook, E. H., Jr., Dawson, G., Schellenberg, G. D., Battaglia, A., Maestrini, E., Autism Genome Project Consortium,, Jeng, L., Hutchison, T., Rajcan-Separovic, E., Chudley, A. E., Lewis, S. M., Liu, X., Holden, J. J., Fernandez, B., Zwaigenbaum, L., Bryson, S. E., Roberts, W., Szatmari, P., Gallagher, L., Stratton, M. R., Gecz, J., Brady, A. F., Schwartz, C. E., Schachar, R. J., Monaco, A. P., Rouleau, G. A., Hui, C. C., Lucy Raymond, F., Scherer, S. W., Vincent, J. B., (2010) Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability. Sci Transl Med, 2:49ra68
    link to pubmed
    
    
51. Mannsperger, H. A., Uhlmann, S., Schmidt, C., Wiemann, S., Sahin, O., Korf, U., (2010) RNAi-based validation of antibodies for reverse phase protein arrays. Proteome Sci, 8:69
    link to pubmed
    
    
52. Mannsperger, H. A., Gade, S., Henjes, F., Beissbarth, T., Korf, U., (2010) RPPanalyzer: Analysis of reverse-phase protein array data. Bioinformatics, 26:2202-3
    link to pubmed
    
    
53. Maestrini, E., Pagnamenta, A. T., Lamb, J. A., Bacchelli, E., Sykes, N. H., Sousa, I., Toma, C., Barnby, G., Butler, H., Winchester, L., Scerri, T. S., Minopoli, F., Reichert, J., Cai, G., Buxbaum, J. D., Korvatska, O., Schellenberg, G. D., Dawson, G., de Bildt, A., Minderaa, R. B., Mulder, E. J., Morris, A. P., Bailey, A. J., Monaco, A. P., (2010) High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. Mol Psychiatry, 15:954-68
    link to pubmed
    
    
54. Johannes, M., Brase, J. C., Frohlich, H., Gade, S., Gehrmann, M., Falth, M., Sultmann, H., Beissbarth, T., (2010) Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients. Bioinformatics, 26:2136-44
    link to pubmed
    
    
55. Jocker, A., Sonntag, J., Henjes, F., Gotschel, F., Tresch, A., Beissbarth, T., Wiemann, S., Korf, U., (2010) QuantProReloaded: quantitative analysis of microspot immunoassays. Bioinformatics, 26:2480-1
    link to pubmed
    
    
56. Holt, R., Barnby, G., Maestrini, E., Bacchelli, E., Brocklebank, D., Sousa, I., Mulder, E. J., Kantojarvi, K., Jarvela, I., Klauck, S. M., Poustka, F., Bailey, A. J., Monaco, A. P., (2010) Linkage and candidate gene studies of autism spectrum disorders in European populations. Eur J Hum Genet, 18:1013-9
    link to pubmed
    
    
57. Haller, F., Zhang, D. J., Lobke, C., von Heydebreck, A., Korf, U., Fuzesi, L., Sahin, O., (2010) [Multilayer analysis of signal transduction and cell cycle control in GIST. Identifying new interaction partners with differential regulation]. Pathologe, 31 Suppl 2:134-7
    link to pubmed
    
    
58. Haller, F., von Heydebreck, A., Zhang, J. D., Gunawan, B., Langer, C., Ramadori, G., Wiemann, S., Sahin, O., (2010) Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31. J Pathol, 220:71-86
    link to pubmed
    
    
59. Freitag, C. M., Staal, W., Klauck, S. M., Duketis, E., Waltes, R., (2010) Genetics of autistic disorders: review and clinical implications. Eur Child Adolesc Psychiatry, 19:169-78
    link to pubmed
    
    
60. de Souza Rocha Simonini, P., Breiling, A., Gupta, N., Malekpour, M., Youns, M., Omranipour, R., Malekpour, F., Volinia, S., Croce, C. M., Najmabadi, H., Diederichs, S., Sahin, O., Mayer, D., Lyko, F., Hoheisel, J. D., Riazalhosseini, Y., (2010) Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res, 70:9175-84
    link to pubmed
    
    
61. Brase, J. C., Wuttig, D., Kuner, R., Sultmann, H., (2010) Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer, 9:306
    link to pubmed
    
    
62. Brase, J. C., Schmidt, M., Fischbach, T., Sultmann, H., Bojar, H., Koelbl, H., Hellwig, B., Rahnenfuhrer, J., Hengstler, J. G., Gehrmann, M. C., (2010) ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction. Clin Cancer Res, 16:2391-401
    link to pubmed
    
    
63. Brase, J. C., Mannsperger, H., Frohlich, H., Gade, S., Schmidt, C., Wiemann, S., Beissbarth, T., Schlomm, T., Sultmann, H., Korf, U., (2010) Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification. Proteome Sci, 8:36
    link to pubmed
    
    
64. Bender, C., Henjes, F., Frohlich, H., Wiemann, S., Korf, U., Beissbarth, T., (2010) Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data. Bioinformatics, 26:i596-602
    link to pubmed
    
    
65. Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., Sykes, N., Pagnamenta, A. T., Almeida, J., Bacchelli, E., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bolte, S., Bolton, P. F., Bourgeron, T., Brennan, S., Brian, J., Carson, A. R., Casallo, G., Casey, J., Chu, S. H., Cochrane, L., Corsello, C., Crawford, E. L., Crossett, A., Dawson, G., de Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B. A., Folstein, S. E., Fombonne, E., Freitag, C. M., Gilbert, J., Gillberg, C., Glessner, J. T., Goldberg, J., Green, J., Guter, S. J., Hakonarson, H., Heron, E. A., Hill, M., Holt, R., Howe, J. L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S. M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C. M., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B. L., Lionel, A. C., Liu, X. Q., Lord, C., Lotspeich, L., Lund, S. C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C. R., McConachie, H., McDougle, C. J., McGrath, J., McMahon, W. M., Melhem, N. M., Merikangas, A., Migita, O., Minshew, N. J., Mirza, G. K., Munson, J., Nelson, S. F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J. R., Parrini, B., Paton, T., Pickles, A., Piven, J., Posey, D. J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M. L., Bierut, L. J., Rice, J. P., Salt, J., Sansom, K., Sato, D., Segurado, R., Senman, L., Shah, N., Sheffield, V. C., Soorya, L., Sousa, I., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A. P., Thomson, S., Tryfon, A., Tsiantis, J., Van Engeland, H., Vincent, J. B., Volkmar, F., Wallace, S., Wang, K., Wang, Z., Wassink, T. H., Wing, K., Wittemeyer, K., Wood, S., Yaspan, B. L., Zurawiecki, D., Zwaigenbaum, L., Betancur, C., Buxbaum, J. D., Cantor, R. M., Cook, E. H., Coon, H., Cuccaro, M. L., Gallagher, L., Geschwind, D. H., Gill, M., Haines, J. L., Miller, J., Monaco, A. P., Nurnberger, J. I., Jr., Paterson, A. D., Pericak-Vance, M. A., Schellenberg, G. D., Scherer, S. W., Sutcliffe, J. S., Szatmari, P., Vicente, A. M., Vieland, V. J., Wijsman, E. M., Devlin, B., Ennis, S., Hallmayer, J., (2010) A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet, 19:4072-82
    link to pubmed
    
    
66. Zhang, J. D., Wiemann, S., (2009) KEGGgraph: a graph approach to KEGG PATHWAY in R and bioconductor. Bioinformatics, 25:1470-1
    link to pubmed
    
    
67. Tschulena, U., Peterson, K. R., Gonzalez, B., Fedosyuk, H., Barbas, C. F., 3rd, (2009) Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production. Nat Struct Mol Biol, 16:1195-9
    link to pubmed
    
    
68. Temple, G., Gerhard, D. S., Rasooly, R., Feingold, E. A., Good, P. J., Robinson, C., Mandich, A., Derge, J. G., Lewis, J., Shoaf, D., Collins, F. S., Jang, W., Wagner, L., Shenmen, C. M., Misquitta, L., Schaefer, C. F., Buetow, K. H., Bonner, T. I., Yankie, L., Ward, M., Phan, L., Astashyn, A., Brown, G., Farrell, C., Hart, J., Landrum, M., Maidak, B. L., Murphy, M., Murphy, T., Rajput, B., Riddick, L., Webb, D., Weber, J., Wu, W., Pruitt, K. D., Maglott, D., Siepel, A., Brejova, B., Diekhans, M., Harte, R., Baertsch, R., Kent, J., Haussler, D., Brent, M., Langton, L., Comstock, C. L., Stevens, M., Wei, C., van Baren, M. J., Salehi-Ashtiani, K., Murray, R. R., Ghamsari, L., Mello, E., Lin, C., Pennacchio, C., Schreiber, K., Shapiro, N., Marsh, A., Pardes, E., Moore, T., Lebeau, A., Muratet, M., Simmons, B., Kloske, D., Sieja, S., Hudson, J., Sethupathy, P., Brownstein, M., Bhat, N., Lazar, J., Jacob, H., Gruber, C. E., Smith, M. R., McPherson, J., Garcia, A. M., Gunaratne, P. H., Wu, J., Muzny, D., Gibbs, R. A., Young, A. C., Bouffard, G. G., Blakesley, R. W., Mullikin, J., Green, E. D., Dickson, M. C., Rodriguez, A. C., Grimwood, J., Schmutz, J., Myers, R. M., Hirst, M., Zeng, T., Tse, K., Moksa, M., Deng, M., Ma, K., Mah, D., Pang, J., Taylor, G., Chuah, E., Deng, A., Fichter, K., Go, A., Lee, S., Wang, J., Griffith, M., Morin, R., Moore, R. A., Mayo, M., Munro, S., Wagner, S., Jones, S. J., Holt, R. A., Marra, M. A., Lu, S., Yang, S., Hartigan, J., Graf, M., Wagner, R., Letovksy, S., Pulido, J. C., Robison, K., Esposito, D., Hartley, J., Wall, V. E., Hopkins, R. F., Ohara, O., Wiemann, S., (2009) The completion of the Mammalian Gene Collection (MGC). Genome Res, 19:2324-33
    link to pubmed
    
    
69. M. G. C. Project Team, Temple, G., Gerhard, D. S., Rasooly, R., Feingold, E. A., Good, P. J., Robinson, C., Mandich, A., Derge, J. G., Lewis, J., Shoaf, D., Collins, F. S., Jang, W., Wagner, L., Shenmen, C. M., Misquitta, L., Schaefer, C. F., Buetow, K. H., Bonner, T. I., Yankie, L., Ward, M., Phan, L., Astashyn, A., Brown, G., Farrell, C., Hart, J., Landrum, M., Maidak, B. L., Murphy, M., Murphy, T., Rajput, B., Riddick, L., Webb, D., Weber, J., Wu, W., Pruitt, K. D., Maglott, D., Siepel, A., Brejova, B., Diekhans, M., Harte, R., Baertsch, R., Kent, J., Haussler, D., Brent, M., Langton, L., Comstock, C. L., Stevens, M., Wei, C., van Baren, M. J., Salehi-Ashtiani, K., Murray, R. R., Ghamsari, L., Mello, E., Lin, C., Pennacchio, C., Schreiber, K., Shapiro, N., Marsh, A., Pardes, E., Moore, T., Lebeau, A., Muratet, M., Simmons, B., Kloske, D., Sieja, S., Hudson, J., Sethupathy, P., Brownstein, M., Bhat, N., Lazar, J., Jacob, H., Gruber, C. E., Smith, M. R., McPherson, J., Garcia, A. M., Gunaratne, P. H., Wu, J., Muzny, D., Gibbs, R. A., Young, A. C., Bouffard, G. G., Blakesley, R. W., Mullikin, J., Green, E. D., Dickson, M. C., Rodriguez, A. C., Grimwood, J., Schmutz, J., Myers, R. M., Hirst, M., Zeng, T., Tse, K., Moksa, M., Deng, M., Ma, K., Mah, D., Pang, J., Taylor, G., Chuah, E., Deng, A., Fichter, K., Go, A., Lee, S., Wang, J., Griffith, M., Morin, R., Moore, R. A., Mayo, M., Munro, S., Wagner, S., Jones, S. J., Holt, R. A., Marra, M. A., Lu, S., Yang, S., Hartigan, J., Graf, M., Wagner, R., Letovksy, S., Pulido, J. C., Robison, K., Esposito, D., Hartley, J., Wall, V. E., Hopkins, R. F., Ohara, O., Wiemann, S., (2009) The completion of the Mammalian Gene Collection (MGC). Genome Res, 19:2324-33
    link to pubmed
    
    
70. Sers, C., Kuner, R., Falk, C. S., Lund, P., Sueltmann, H., Braun, M., Buness, A., Ruschhaupt, M., Conrad, J., Mang-Fatehi, S., Stelniec, I., Krapfenbauer, U., Poustka, A., Schafer, R., (2009) Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells. Int J Cancer, 125:1626-39
    link to pubmed
    
    
71. Schlomm, T., Sultmann, H., Kollermann, J., (2009) [Identification and validation of clinically relevant molecular alterations in prostate cancer]. Pathologe, 30:111-6
    link to pubmed
    
    
72. Schlomm, T., Hellwinkel, O. J., Buness, A., Ruschhaupt, M., Lubke, A. M., Chun, F. K., Simon, R., Budaus, L., Erbersdobler, A., Graefen, M., Huland, H., Poustka, A., Sultmann, H., (2009) Molecular cancer phenotype in normal prostate tissue. Eur Urol, 55:885-90
    link to pubmed
    
    
73. Sahin, O., Wiemann, S., (2009) Functional genomics and proteomics approaches to study the ERBB network in cancer. FEBS Lett, 583:1766-71
    link to pubmed
    
    
74. Sahin, O., Frohlich, H., Lobke, C., Korf, U., Burmester, S., Majety, M., Mattern, J., Schupp, I., Chaouiya, C., Thieffry, D., Poustka, A., Wiemann, S., Beissbarth, T., Arlt, D., (2009) Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance. BMC Syst Biol, 3:1
    link to pubmed
    
    
75. Pressinotti, N. C., Klocker, H., Schafer, G., Luu, V. D., Ruschhaupt, M., Kuner, R., Steiner, E., Poustka, A., Bartsch, G., Sultmann, H., (2009) Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer. Mol Cancer, 8:130
    link to pubmed
    
    
76. Poustka, F., Freitag, C., Klauck, S., Hebebrand, J., (2009) [Autism]. Z Kinder Jugendpsychiatr Psychother, 37:269-75
    link to pubmed
    
    
77. Pagnamenta, A. T., Wing, K., Sadighi Akha, E., Knight, S. J., Bolte, S., Schmotzer, G., Duketis, E., Poustka, F., Klauck, S. M., Poustka, A., Ragoussis, J., Bailey, A. J., Monaco, A. P., (2009) A 15q13.3 microdeletion segregating with autism. Eur J Hum Genet, 17:687-92
    link to pubmed
    
    
78. Kuner, R., Muley, T., Meister, M., Ruschhaupt, M., Buness, A., Xu, E. C., Schnabel, P., Warth, A., Poustka, A., Sultmann, H., Hoffmann, H., (2009) Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes. Lung Cancer, 63:32-8
    link to pubmed
    
    
79. Kuner, R., Hoffmann, H., Sultmann, H., (2009) [Gene expression profiling in lung cancer. Experimental research and clinical application]. Dtsch Med Wochenschr, 134:519-21
    link to pubmed
    
    
80. Korf, U., Lobke, C., Sahin, O., Haller, F., Sultmann, H., Arlt, D., Poustka, A., (2009) Reverse-phase protein arrays for application-orientated cancer research. Proteomics Clin Appl, 3:1140-50
    link to pubmed
    
    
81. Kahn, N., Kuner, R., Eberhardt, R., Meister, M., Muley, T., Winteroll, S., Schnabel, P. A., Ishizaka, A., Herth, F. J., Poustka, A., Sultmann, H., Hoffmann, H., (2009) Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules. J Thorac Cardiovasc Surg, 138:474-9
    link to pubmed
    
    
82. Helmke, B. M., Renner, M., Poustka, A., Schirmacher, P., Mollenhauer, J., Kern, M. A., (2009) DMBT1 expression distinguishes anorectal from cutaneous melanoma. Histopathology, 54:233-40
    link to pubmed
    
    
83. Hagist, S., Sultmann, H., Millonig, G., Hebling, U., Kieslich, D., Kuner, R., Balaguer, S., Seitz, H. K., Poustka, A., Mueller, S., (2009) In vitro-targeted gene identification in patients with hepatitis C using a genome-wide microarray technology. Hepatology, 49:378-86
    link to pubmed
    
    
84. Felder, B., Radlwimmer, B., Benner, A., Mincheva, A., Todt, G., Beyer, K. S., Schuster, C., Bolte, S., Schmotzer, G., Klauck, S. M., Poustka, F., Lichter, P., Poustka, A., (2009) FARP2, HDLBP and PASK are downregulated in a patient with autism and 2q37.3 deletion syndrome. Am J Med Genet A, 149A:952-9
    link to pubmed
    
    
85. End, C., Bikker, F., Renner, M., Bergmann, G., Lyer, S., Blaich, S., Hudler, M., Helmke, B., Gassler, N., Autschbach, F., Ligtenberg, A. J., Benner, A., Holmskov, U., Schirmacher, P., Nieuw Amerongen, A. V., Rosenstiel, P., Sina, C., Franke, A., Hafner, M., Kioschis, P., Schreiber, S., Poustka, A., Mollenhauer, J., (2009) DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands. Eur J Immunol, 39:833-42
    link to pubmed
    
    
86. Calabro, A., Beissbarth, T., Kuner, R., Stojanov, M., Benner, A., Asslaber, M., Ploner, F., Zatloukal, K., Samonigg, H., Poustka, A., Sultmann, H., (2009) Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer. Breast Cancer Res Treat, 116:69-77
    link to pubmed
    
    
87. Yamasaki, C., Murakami, K., Fujii, Y., Sato, Y., Harada, E., Takeda, J., Taniya, T., Sakate, R., Kikugawa, S., Shimada, M., Tanino, M., Koyanagi, K. O., Barrero, R. A., Gough, C., Chun, H. W., Habara, T., Hanaoka, H., Hayakawa, Y., Hilton, P. B., Kaneko, Y., Kanno, M., Kawahara, Y., Kawamura, T., Matsuya, A., Nagata, N., Nishikata, K., Noda, A. O., Nurimoto, S., Saichi, N., Sakai, H., Sanbonmatsu, R., Shiba, R., Suzuki, M., Takabayashi, K., Takahashi, A., Tamura, T., Tanaka, M., Tanaka, S., Todokoro, F., Yamaguchi, K., Yamamoto, N., Okido, T., Mashima, J., Hashizume, A., Jin, L., Lee, K. B., Lin, Y. C., Nozaki, A., Sakai, K., Tada, M., Miyazaki, S., Makino, T., Ohyanagi, H., Osato, N., Tanaka, N., Suzuki, Y., Ikeo, K., Saitou, N., Sugawara, H., O'Donovan, C., Kulikova, T., Whitfield, E., Halligan, B., Shimoyama, M., Twigger, S., Yura, K., Kimura, K., Yasuda, T., Nishikawa, T., Akiyama, Y., Motono, C., Mukai, Y., Nagasaki, H., Suwa, M., Horton, P., Kikuno, R., Ohara, O., Lancet, D., Eveno, E., Graudens, E., Imbeaud, S., Debily, M. A., Hayashizaki, Y., Amid, C., Han, M., Osanger, A., Endo, T., Thomas, M. A., Hirakawa, M., Makalowski, W., Nakao, M., Kim, N. S., Yoo, H. S., De Souza, S. J., Bonaldo Mde, F., Niimura, Y., Kuryshev, V., Schupp, I., Wiemann, S., Bellgard, M., Shionyu, M., Jia, L., Thierry-Mieg, D., Thierry-Mieg, J., Wagner, L., Zhang, Q., Go, M., Minoshima, S., Ohtsubo, M., Hanada, K., Tonellato, P., Isogai, T., Zhang, J., Lenhard, B., Kim, S., Chen, Z., Hinz, U., Estreicher, A., Nakai, K., Makalowska, I., Hide, W., Tiffin, N., Wilming, L., Chakraborty, R., Soares, M. B., Chiusano, M. L., Auffray, C., Yamaguchi-Kabata, Y., Itoh, T., Hishiki, T., Fukuchi, S., Nishikawa, K., Sugano, S., Nomura, N., Tateno, Y., Imanishi, T., Gojobori, T., (2008) The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res, 36:D793-9
    link to pubmed
    
    
88. Westermann, F., Muth, D., Benner, A., Bauer, T., Henrich, K. O., Oberthuer, A., Brors, B., Beissbarth, T., Vandesompele, J., Pattyn, F., Hero, B., Konig, R., Fischer, M., Schwab, M., (2008) Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol, 9:R150
    link to pubmed
    
    
89. Van Laere, S., Beissbarth, T., Van der Auwera, I., Van den Eynden, G., Trinh, X. B., Elst, H., Van Hummelen, P., van Dam, P., Van Marck, E., Vermeulen, P., Dirix, L., (2008) Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer. Clin Cancer Res, 14:7452-60
    link to pubmed
    
    
90. Taylor, C. F., Field, D., Sansone, S. A., Aerts, J., Apweiler, R., Ashburner, M., Ball, C. A., Binz, P. A., Bogue, M., Booth, T., Brazma, A., Brinkman, R. R., Michael Clark, A., Deutsch, E. W., Fiehn, O., Fostel, J., Ghazal, P., Gibson, F., Gray, T., Grimes, G., Hancock, J. M., Hardy, N. W., Hermjakob, H., Julian, R. K., Jr., Kane, M., Kettner, C., Kinsinger, C., Kolker, E., Kuiper, M., Le Novere, N., Leebens-Mack, J., Lewis, S. E., Lord, P., Mallon, A. M., Marthandan, N., Masuya, H., McNally, R., Mehrle, A., Morrison, N., Orchard, S., Quackenbush, J., Reecy, J. M., Robertson, D. G., Rocca-Serra, P., Rodriguez, H., Rosenfelder, H., Santoyo-Lopez, J., Scheuermann, R. H., Schober, D., Smith, B., Snape, J., Stoeckert, C. J., Jr., Tipton, K., Sterk, P., Untergasser, A., Vandesompele, J., Wiemann, S., (2008) Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol, 26:889-96
    link to pubmed
    
    
91. Stadler, V., Felgenhauer, T., Beyer, M., Fernandez, S., Leibe, K., Guttler, S., Groning, M., Konig, K., Torralba, G., Hausmann, M., Lindenstruth, V., Nesterov, A., Block, I., Pipkorn, R., Poustka, A., Bischoff, F. R., Breitling, F., (2008) Combinatorial synthesis of peptide arrays with a laser printer. Angew Chem Int Ed Engl, 47:7132-5
    link to pubmed
    
    
92. Schlomm, T., Sultmann, H., Kollermann, J., (2008) [Identification and validation of clinically relevant molecular alterations in prostate cancer]. Urologe A, 47:1193-8
    link to pubmed
    
    
93. Schlomm, T., Nakel, E., Lubke, A., Buness, A., Chun, F. K., Steuber, T., Graefen, M., Simon, R., Sauter, G., Poustka, A., Huland, H., Erbersdobler, A., Sultmann, H., Hellwinkel, O. J., (2008) Marked gene transcript level alterations occur early during radical prostatectomy. Eur Urol, 53:333-46
    link to pubmed
    
    
94. Sauermann, M., Sahin, O., Sultmann, H., Hahne, F., Blaszkiewicz, S., Majety, M., Zatloukal, K., Fuzesi, L., Poustka, A., Wiemann, S., Arlt, D., (2008) Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells. Oncogene, 27:1320-6
    link to pubmed
    
    
95. Sansone, S. A., Rocca-Serra, P., Brandizi, M., Brazma, A., Field, D., Fostel, J., Garrow, A. G., Gilbert, J., Goodsaid, F., Hardy, N., Jones, P., Lister, A., Miller, M., Morrison, N., Rayner, T., Sklyar, N., Taylor, C., Tong, W., Warner, G., Wiemann, S., (2008) The first RSBI (ISA-TAB) workshop: "can a simple format work for complex studies?". Omics, 12:143-9
    link to pubmed
    
    
96. Retz, W., Rosler, M., Kissling, C., Wiemann, S., Hunnerkopf, R., Coogan, A., Thome, J., Freitag, C., (2008) Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults. J Neural Transm, 115:323-9
    link to pubmed
    
    
97. Praml, C., Schulz, W., Claas, A., Mollenhauer, J., Poustka, A., Ackermann, R., Schwab, M., Henrich, K. O., (2008) Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells. Cancer Lett, 272:160-6
    link to pubmed
    
    
98. Pepperkok, R., Wiemann, S., (2008) Integrating systems biology with clinical research. Genome Biol, 9:314
    link to pubmed
    
    
99. Muller, H., End, C., Weiss, C., Renner, M., Bhandiwad, A., Helmke, B. M., Gassler, N., Hafner, M., Poustka, A., Mollenhauer, J., Poeschl, J., (2008) Respiratory Deleted in Malignant Brain Tumours 1 (DMBT1) levels increase during lung maturation and infection. Clin Exp Immunol, 151:123-9
    link to pubmed
    
    
100. Michaud, J., Simpson, K. M., Escher, R., Buchet-Poyau, K., Beissbarth, T., Carmichael, C., Ritchie, M. E., Schutz, F., Cannon, P., Liu, M., Shen, X., Ito, Y., Raskind, W. H., Horwitz, M. S., Osato, M., Turner, D. R., Speed, T. P., Kavallaris, M., Smyth, G. K., Scott, H. S., (2008) Integrative analysis of RUNX1 downstream pathways and target genes. BMC Genomics, 9:363
     link to pubmed
     
     
101. Mathivanan, S., Ahmed, M., Ahn, N. G., Alexandre, H., Amanchy, R., Andrews, P. C., Bader, J. S., Balgley, B. M., Bantscheff, M., Bennett, K. L., Bjorling, E., Blagoev, B., Bose, R., Brahmachari, S. K., Burlingame, A. S., Bustelo, X. R., Cagney, G., Cantin, G. T., Cardasis, H. L., Celis, J. E., Chaerkady, R., Chu, F., Cole, P. A., Costello, C. E., Cotter, R. J., Crockett, D., DeLany, J. P., De Marzo, A. M., DeSouza, L. V., Deutsch, E. W., Dransfield, E., Drewes, G., Droit, A., Dunn, M. J., Elenitoba-Johnson, K., Ewing, R. M., Van Eyk, J., Faca, V., Falkner, J., Fang, X., Fenselau, C., Figeys, D., Gagne, P., Gelfi, C., Gevaert, K., Gimble, J. M., Gnad, F., Goel, R., Gromov, P., Hanash, S. M., Hancock, W. S., Harsha, H. C., Hart, G., Hays, F., He, F., Hebbar, P., Helsens, K., Hermeking, H., Hide, W., Hjerno, K., Hochstrasser, D. F., Hofmann, O., Horn, D. M., Hruban, R. H., Ibarrola, N., James, P., Jensen, O. N., Jensen, P. H., Jung, P., Kandasamy, K., Kheterpal, I., Kikuno, R. F., Korf, U., Korner, R., Kuster, B., Kwon, M. S., Lee, H. J., Lee, Y. J., Lefevre, M., Lehvaslaiho, M., Lescuyer, P., Levander, F., Lim, M. S., Lobke, C., Loo, J. A., Mann, M., Martens, L., Martinez-Heredia, J., McComb, M., McRedmond, J., Mehrle, A., Menon, R., Miller, C. A., Mischak, H., Mohan, S. S., Mohmood, R., Molina, H., Moran, M. F., Morgan, J. D., Moritz, R., Morzel, M., Muddiman, D. C., Nalli, A., Navarro, J. D., Neubert, T. A., Ohara, O., Oliva, R., Omenn, G. S., Oyama, M., Paik, Y. K., Pennington, K., Pepperkok, R., Periaswamy, B., Petricoin, E. F., Poirier, G. G., Prasad, T. S., Purvine, S. O., Rahiman, B. A., Ramachandran, P., Ramachandra, Y. L., Rice, R. H., Rick, J., Ronnholm, R. H., Salonen, J., Sanchez, J. C., Sayd, T., Seshi, B., Shankari, K., Sheng, S. J., Shetty, V., Shivakumar, K., Simpson, R. J., Sirdeshmukh, R., Siu, K. W., Smith, J. C., Smith, R. D., States, D. J., Sugano, S., Sullivan, M., Superti-Furga, G., Takatalo, M., Thongboonkerd, V., Trinidad, J. C., Uhlen, M., Vandekerckhove, J., Vasilescu, J., Veenstra, T. D., Vidal-Taboada, J. M., Vihinen, M., Wait, R., Wang, X., Wiemann, S., Wu, B., Xu, T., Yates, J. R., Zhong, J., Zhou, M., Zhu, Y., Zurbig, P., Pandey, A., (2008) Human Proteinpedia enables sharing of human protein data. Nat Biotechnol, 26:164-7
     link to pubmed
     
     
102. Lobke, C., Laible, M., Rappl, C., Ruschhaupt, M., Sahin, O., Arlt, D., Wiemann, S., Poustka, A., Sultmann, H., Korf, U., (2008) Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling. Proteomics, 8:1586-94
     link to pubmed
     
     
103. Kuner, R., Barth, A. S., Ruschhaupt, M., Buness, A., Zwermann, L., Kreuzer, E., Steinbeck, G., Poustka, A., Sultmann, H., Nabauer, M., (2008) Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies. Physiol Genomics, 34:88-94
     link to pubmed
     
     
104. Korf, U., Henjes, F., Schmidt, C., Tresch, A., Mannsperger, H., Lobke, C., Beissbarth, T., Poustka, A., (2008) Antibody microarrays as an experimental platform for the analysis of signal transduction networks. Adv Biochem Eng Biotechnol, 110:153-75
     link to pubmed
     
     
105. Korf, U., Derdak, S., Tresch, A., Henjes, F., Schumacher, S., Schmidt, C., Hahn, B., Lehmann, W. D., Poustka, A., Beissbarth, T., Klingmuller, U., (2008) Quantitative protein microarrays for time-resolved measurements of protein phosphorylation. Proteomics, 8:4603-12
     link to pubmed
     
     
106. Kohl, T., Schmidt, C., Wiemann, S., Poustka, A., Korf, U., (2008) Automated production of recombinant human proteins as resource for proteome research. Proteome Sci, 6:4
     link to pubmed
     
     
107. Kleber, S., Sancho-Martinez, I., Wiestler, B., Beisel, A., Gieffers, C., Hill, O., Thiemann, M., Mueller, W., Sykora, J., Kuhn, A., Schreglmann, N., Letellier, E., Zuliani, C., Klussmann, S., Teodorczyk, M., Grone, H. J., Ganten, T. M., Sultmann, H., Tuttenberg, J., von Deimling, A., Regnier-Vigouroux, A., Herold-Mende, C., Martin-Villalba, A., (2008) Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell, 13:235-48
     link to pubmed
     
     
108. Kissling, C., Retz, W., Wiemann, S., Coogan, A. N., Clement, R. M., Hunnerkopf, R., Conner, A. C., Freitag, C. M., Rosler, M., Thome, J., (2008) A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet, 147:333-8
     link to pubmed
     
     
109. Haller, F., Lobke, C., Ruschhaupt, M., Schulten, H. J., Schwager, S., Gunawan, B., Armbrust, T., Langer, C., Ramadori, G., Sultmann, H., Poustka, A., Korf, U., Fuzesi, L., (2008) Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions. J Pathol, 216:225-35
     link to pubmed
     
     
110. Haller, F., Lobke, C., Ruschhaupt, M., Cameron, S., Schulten, H. J., Schwager, S., von Heydebreck, A., Gunawan, B., Langer, C., Ramadori, G., Sultmann, H., Poustka, A., Korf, U., Fuzesi, L., (2008) Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs). J Pathol, 215:253-62
     link to pubmed
     
     
111. Hahne, F., Mehrle, A., Arlt, D., Poustka, A., Wiemann, S., Beissbarth, T., (2008) Extending pathways based on gene lists using InterPro domain signatures. BMC Bioinformatics, 9:3
     link to pubmed
     
     
112. Genome Information Integration, Project, H. Invitational, Yamasaki, C., Murakami, K., Fujii, Y., Sato, Y., Harada, E., Takeda, J., Taniya, T., Sakate, R., Kikugawa, S., Shimada, M., Tanino, M., Koyanagi, K. O., Barrero, R. A., Gough, C., Chun, H. W., Habara, T., Hanaoka, H., Hayakawa, Y., Hilton, P. B., Kaneko, Y., Kanno, M., Kawahara, Y., Kawamura, T., Matsuya, A., Nagata, N., Nishikata, K., Noda, A. O., Nurimoto, S., Saichi, N., Sakai, H., Sanbonmatsu, R., Shiba, R., Suzuki, M., Takabayashi, K., Takahashi, A., Tamura, T., Tanaka, M., Tanaka, S., Todokoro, F., Yamaguchi, K., Yamamoto, N., Okido, T., Mashima, J., Hashizume, A., Jin, L., Lee, K. B., Lin, Y. C., Nozaki, A., Sakai, K., Tada, M., Miyazaki, S., Makino, T., Ohyanagi, H., Osato, N., Tanaka, N., Suzuki, Y., Ikeo, K., Saitou, N., Sugawara, H., O'Donovan, C., Kulikova, T., Whitfield, E., Halligan, B., Shimoyama, M., Twigger, S., Yura, K., Kimura, K., Yasuda, T., Nishikawa, T., Akiyama, Y., Motono, C., Mukai, Y., Nagasaki, H., Suwa, M., Horton, P., Kikuno, R., Ohara, O., Lancet, D., Eveno, E., Graudens, E., Imbeaud, S., Debily, M. A., Hayashizaki, Y., Amid, C., Han, M., Osanger, A., Endo, T., Thomas, M. A., Hirakawa, M., Makalowski, W., Nakao, M., Kim, N. S., Yoo, H. S., De Souza, S. J., Bonaldo Mde, F., Niimura, Y., Kuryshev, V., Schupp, I., Wiemann, S., Bellgard, M., Shionyu, M., Jia, L., Thierry-Mieg, D., Thierry-Mieg, J., Wagner, L., Zhang, Q., Go, M., Minoshima, S., Ohtsubo, M., Hanada, K., Tonellato, P., Isogai, T., Zhang, J., Lenhard, B., Kim, S., Chen, Z., Hinz, U., Estreicher, A., Nakai, K., Makalowska, I., Hide, W., Tiffin, N., Wilming, L., Chakraborty, R., Soares, M. B., Chiusano, M. L., Suzuki, Y., Auffray, C., Yamaguchi-Kabata, Y., Itoh, T., Hishiki, T., Fukuchi, S., Nishikawa, K., Sugano, S., Nomura, N., Tateno, Y., Imanishi, T., Gojobori, T., (2008) The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res, 36:D793-9
     link to pubmed
     
     
113. Frohlich, H., Fellmann, M., Sultmann, H., Poustka, A., Beissbarth, T., (2008) Predicting pathway membership via domain signatures. Bioinformatics, 24:2137-42
     link to pubmed
     
     
114. Frohlich, H., Fellmann, M., Sultmann, H., Poustka, A., Beissbarth, T., (2008) Estimating Large Scale Signaling Networks through Nested Effect Models with Intervention Effects from Microarray Data. Bioinformatics, :
     link to pubmed
     
     
115. Frohlich, H., Beissbarth, T., Tresch, A., Kostka, D., Jacob, J., Spang, R., Markowetz, F., (2008) Analyzing gene perturbation screens with nested effects models in R and bioconductor. Bioinformatics, 24:2549-50
     link to pubmed
     
     
116. Eisenberger, S., Ackermann, K., Voggenreiter, G., Sultmann, H., Kasperk, C., Pyerin, W., (2008) Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo. J Pathol, 214:617-26
     link to pubmed
     
     
117. Cheung, W., Darfler, M. M., Alvarez, H., Hood, B. L., Conrads, T. P., Habbe, N., Krizman, D. B., Mollenhauer, J., Feldmann, G., Maitra, A., (2008) Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors. Pancreatology, 8:608-16
     link to pubmed
     
     
118. Boeuf, S., Steck, E., Pelttari, K., Hennig, T., Buness, A., Benz, K., Witte, D., Sultmann, H., Poustka, A., Richter, W., (2008) Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers. Osteoarthritis Cartilage, 16:48-60
     link to pubmed
     
     
119. Tresch, A., Beissbarth, T., Sultmann, H., Kuner, R., Poustka, A., Buness, A., (2007) Discrimination of direct and indirect interactions in a network of regulatory effects. J Comput Biol, 14:1217-28
     link to pubmed
     
     
120. Szatmari, P., Paterson, A. D., Zwaigenbaum, L., Roberts, W., Brian, J., Liu, X. Q., Vincent, J. B., Skaug, J. L., Thompson, A. P., Senman, L., Feuk, L., Qian, C., Bryson, S. E., Jones, M. B., Marshall, C. R., Scherer, S. W., Vieland, V. J., Bartlett, C., Mangin, L. V., Goedken, R., Segre, A., Pericak-Vance, M. A., Cuccaro, M. L., Gilbert, J. R., Wright, H. H., Abramson, R. K., Betancur, C., Bourgeron, T., Gillberg, C., Leboyer, M., Buxbaum, J. D., Davis, K. L., Hollander, E., Silverman, J. M., Hallmayer, J., Lotspeich, L., Sutcliffe, J. S., Haines, J. L., Folstein, S. E., Piven, J., Wassink, T. H., Sheffield, V., Geschwind, D. H., Bucan, M., Brown, W. T., Cantor, R. M., Constantino, J. N., Gilliam, T. C., Herbert, M., Lajonchere, C., Ledbetter, D. H., Lese-Martin, C., Miller, J., Nelson, S., Samango-Sprouse, C. A., Spence, S., State, M., Tanzi, R. E., Coon, H., Dawson, G., Devlin, B., Estes, A., Flodman, P., Klei, L., McMahon, W. M., Minshew, N., Munson, J., Korvatska, E., Rodier, P. M., Schellenberg, G. D., Smith, M., Spence, M. A., Stodgell, C., Tepper, P. G., Wijsman, E. M., Yu, C. E., Roge, B., Mantoulan, C., Wittemeyer, K., Poustka, A., Felder, B., Klauck, S. M., Schuster, C., Poustka, F., Bolte, S., Feineis-Matthews, S., Herbrecht, E., Schmotzer, G., Tsiantis, J., Papanikolaou, K., Maestrini, E., Bacchelli, E., Blasi, F., Carone, S., Toma, C., Van Engeland, H., de Jonge, M., Kemner, C., Koop, F., Langemeijer, M., Hijmans, C., Staal, W. G., Baird, G., Bolton, P. F., Rutter, M. L., Weisblatt, E., Green, J., Aldred, C., Wilkinson, J. A., Pickles, A., Le Couteur, A., Berney, T., McConachie, H., Bailey, A. J., Francis, K., Honeyman, G., Hutchinson, A., Parr, J. R., Wallace, S., Monaco, A. P., Barnby, G., Kobayashi, K., Lamb, J. A., Sousa, I., Sykes, N., Cook, E. H., Guter, S. J., Leventhal, B. L., Salt, J., Lord, C., Corsello, C., Hus, V., Weeks, D. E., Volkmar, F., Tauber, M., Fombonne, E., Shih, A., Meyer, K. J., (2007) Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet, 39:319-28
     link to pubmed
     
     
121. Schlomm, T., Sultmann, H., Poustka, A., Sauter, G., Hellwinkel, O. J., Huland, H., (2007) Molekulare Hochdurchsatzforschung beim Prostatakarzinom. Urologe A, 46:1097-1100
     link to pubmed
     
     
122. Sauermann, M., Hahne, F., Schmidt, C., Majety, M., Rosenfelder, H., Bechtel, S., Huber, W., Poustka, A., Arlt, D., Wiemann, S., (2007) High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins. J Biomol Screen, 12:510-20
     link to pubmed
     
     
123. Sahin, O., Lobke, C., Korf, U., Appelhans, H., Sultmann, H., Poustka, A., Wiemann, S., Arlt, D., (2007) Combinatorial RNAi for quantitative protein network analysis. Proc Natl Acad Sci U S A, 104:6579-84
     link to pubmed
     
     
124. Rosenstiel, P., Sina, C., End, C., Renner, M., Lyer, S., Till, A., Hellmig, S., Nikolaus, S., Folsch, U. R., Helmke, B., Autschbach, F., Schirmacher, P., Kioschis, P., Hafner, M., Poustka, A., Mollenhauer, J., Schreiber, S., (2007) Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion. J Immunol, 178:8203-11
     link to pubmed
     
     
125. Renner, M., Bergmann, G., Krebs, I., End, C., Lyer, S., Hilberg, F., Helmke, B., Gassler, N., Autschbach, F., Bikker, F., Strobel-Freidekind, O., Gronert-Sum, S., Benner, A., Blaich, S., Wittig, R., Hudler, M., Ligtenberg, A. J., Madsen, J., Holmskov, U., Annese, V., Latiano, A., Schirmacher, P., Amerongen, A. V., D'Amato, M., Kioschis, P., Hafner, M., Poustka, A., Mollenhauer, J., (2007) DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease. Gastroenterology, 133:1499-509
     link to pubmed
     
     
126. Muller, H., End, C., Renner, M., Helmke, B. M., Gassler, N., Weiss, C., Hartl, D., Griese, M., Hafner, M., Poustka, A., Mollenhauer, J., Poeschl, J., (2007) Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant. Respir Res, 8:69
     link to pubmed
     
     
127. Loebke, C., Sueltmann, H., Schmidt, C., Henjes, F., Wiemann, S., Poustka, A., Korf, U., (2007) Infrared-based protein detection arrays for quantitative proteomics. Proteomics, 7:558-64
     link to pubmed
     
     
128. Ligtenberg, A. J., Veerman, E. C., Nieuw Amerongen, A. V., Mollenhauer, J., (2007) Salivary agglutinin/glycoprotein-340/DMBT1: a single molecule with variable composition and with different functions in infection, inflammation and cancer. Biol Chem, 388:1275-89
     link to pubmed
     
     
129. Laketa, V., Simpson, J. C., Bechtel, S., Wiemann, S., Pepperkok, R., (2007) High-content microscopy identifies new neurite outgrowth regulators. Mol Biol Cell, 18:242-52
     link to pubmed
     
     
130. Kuner, R., Vogt, M., Sultmann, H., Buness, A., Dymalla, S., Bulkescher, J., Fellmann, M., Butz, K., Poustka, A., Hoppe-Seyler, F., (2007) Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses. J Mol Med, :
     link to pubmed
     
     
131. Klauck, S. M. , Poustka, F., Poustka, A., (2007) Autismus mit einem Spektrum an Verhaltensstörungen. Ursachenforschung zwischen Phänotyp und Genotyp im internationalen Netzwerk.. GenomXPress, 3:19-22
     
     
     
132. Kissling, C., Retz, W., Wiemann, S., Coogan, A. N., Clement, R. M., Hunnerkopf, R., Conner, A. C., Freitag, C. M., Rosler, M., Thome, J., (2007) A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet, :
     link to pubmed
     
     
133. Henrich, K. O., Claas, A., Praml, C., Benner, A., Mollenhauer, J., Poustka, A., Schwab, M., Westermann, F., (2007) Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma. Eur J Cancer, 43:607-16
     link to pubmed
     
     
134. Geldyyev, A., Koleganova, N., Piecha, G., Sueltmann, H., Finis, K., Ruschaupt, M., Poustka, A., Gross, M. L., Berger, I., (2007) High expression level of bone degrading proteins as a possible inducer of osteolytic features in pigmented villonodular synovitis. Cancer Lett, 255:275-83
     link to pubmed
     
     
135. Frohlich, H., Speer, N., Poustka, A., Beissbarth, T., (2007) GOSim--an R-package for computation of information theoretic GO similarities between terms and gene products. BMC Bioinformatics, 8:166
     link to pubmed
     
     
136. Froehlich, H., Fellmann, M., Sueltmann, H., Poustka, A., Beissbarth, T., (2007) Large scale statistical inference of signaling pathways from RNAi and microarray data. BMC Bioinformatics, 8:386
     link to pubmed
     
     
137. Conde, A. R., Martins, A. P., Brito, M., Manuel, A., Ramos, S., Malta-Vacas, J., Renner, M., Poustka, A., Mollenhauer, J., Monteiro, C., (2007) DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types. Int J Oncol, 30:1441-6
     link to pubmed
     
     
138. Buness, A., Kuner, R., Ruschhaupt, M., Poustka, A., Sultmann, H., Tresch, A., (2007) Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer. Bioinformatics, 23:2273-80
     link to pubmed
     
     
139. Brueckner, B., Stresemann, C., Kuner, R., Mund, C., Musch, T., Meister, M., Sultmann, H., Lyko, F., (2007) The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function. Cancer Res, 67:1419-23
     link to pubmed
     
     
140. Blackburn, A. C., Hill, L. Z., Roberts, A. L., Wang, J., Aud, D., Jung, J., Nikolcheva, T., Allard, J., Peltz, G., Otis, C. N., Cao, Q. J., Ricketts, R. S., Naber, S. P., Mollenhauer, J., Poustka, A., Malamud, D., Jerry, D. J., (2007) Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk. Am J Pathol, 170:2030-41
     link to pubmed
     
     
141. Bechtel, S., Rosenfelder, H., Duda, A., Schmidt, C. P., Ernst, U., Wellenreuther, R., Mehrle, A., Schuster, C., Bahr, A., Blocker, H., Heubner, D., Hoerlein, A., Michel, G., Wedler, H., Kohrer, K., Ottenwalder, B., Poustka, A., Wiemann, S., Schupp, I., (2007) The full-ORF clone resource of the German cDNA Consortium. BMC Genomics, 8:399
     link to pubmed
     
     
142. Treutlein, J., Kissling, C., Frank, J., Wiemann, S., Dong, L., Depner, M., Saam, C., Lascorz, J., Soyka, M., Preuss, U. W., Rujescu, D., Skowronek, M. H., Rietschel, M., Spanagel, R., Heinz, A., Laucht, M., Mann, K., Schumann, G., (2006) Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol Psychiatry, 11:594-602
     link to pubmed
     
     
143. Takeda, J., Suzuki, Y., Nakao, M., Barrero, R. A., Koyanagi, K. O., Jin, L., Motono, C., Hata, H., Isogai, T., Nagai, K., Otsuki, T., Kuryshev, V., Shionyu, M., Yura, K., Go, M., Thierry-Mieg, J., Thierry-Mieg, D., Wiemann, S., Nomura, N., Sugano, S., Gojobori, T., Imanishi, T., (2006) Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56,419 completely sequenced and manually annotated full-length cDNAs. Nucleic Acids Res, 34:3917-28
     link to pubmed
     
     
144. Sultmann, H., Poustka, A., (2006) [Microarrays for the identification of molecular markers in the diagnosis and therapy of renal cell carcinomas.]. Urologe A, 45:297-304
     link to pubmed
     
     
145. Seiler, M., Mehrle, A., Poustka, A., Wiemann, S., (2006) The 3of5 web application for complex and comprehensive pattern matching in protein sequences. BMC Bioinformatics, 7:144
     link to pubmed
     
     
146. Schneider, J., Ruschhaupt, M., Buness, A., Asslaber, M., Regitnig, P., Zatloukal, K., Schippinger, W., Ploner, F., Poustka, A., Sultmann, H., (2006) Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer. Int J Cancer, 119:2974-9
     link to pubmed
     
     
147. Orchard, S., Apweiler, R., Barkovich, R., Field, D., Garavelli, J. S., Horn, D., Jones, A., Jones, P., Julian, R., McNally, R., Nerothin, J., Paton, N., Pizarro, A., Seymour, S., Taylor, C., Wiemann, S., Hermjakob, H., (2006) Proteomics and Beyond: a report on the 3rd Annual Spring Workshop of the HUPO-PSI 21-23 April 2006, San Francisco, CA, USA. Proteomics, 6:4439-43
     link to pubmed
     
     
148. Mehrle, A., Rosenfelder, H., Schupp, I., Del Val, C., Arlt, D., Hahne, F., Bechtel, S., Simpson, J., Hofmann, O., Hide, W., Glatting, K. H., Huber, W., Pepperkok, R., Poustka, A., Wiemann, S., (2006) The LIFEdb database in 2006. Nucleic Acids Res, 34:D415-8
     link to pubmed
     
     
149. Kuryshev, V. Y., Vorobyov, E., Zink, D., Schmitz, J., Rozhdestvensky, T. S., Munstermann, E., Ernst, U., Wellenreuther, R., Moosmayer, P., Bechtel, S., Schupp, I., Horst, J., Korn, B., Poustka, A., Wiemann, S., (2006) An anthropoid-specific segmental duplication on human chromosome 1q22. Genomics, 88:143-51
     link to pubmed
     
     
150. Kolb-Kokocinski, A, Mehrle, A, Bechtel, S, Simpson, AJ, Kioschis, P, Wiemann, S, Wellenreuther, R, Poustka, A, (2006) The systematic functional characterisation of Xq28 genes prioritises candidate disease genes. BMC Genomics, 7:29
     link to pubmed
     
     
151. Klauck, S. M., Felder, B., Kolb-Kokocinski, A., Schuster, C., Chiocchetti, A., Schupp, I., Wellenreuther, R., Schmotzer, G., Poustka, F., Breitenbach-Koller, L., Poustka, A., (2006) Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autism. Mol Psychiatry, 11:1073-84
     link to pubmed
     
     
152. Klauck, S. M., (2006) Genetics of autism spectrum disorder. Eur J Hum Genet, 14:714-20
     link to pubmed
     
     
153. Klauck, S. , Poustka, A., (2006) Animal models of autism.. Drug Discovery Today: Disease Models, 3:313-18
     link to pubmed
     
     
154. Hahne, F., Arlt, D., Sauermann, M., Majety, M., Poustka, A., Wiemann, S., Huber, W., (2006) Statistical methods and software for the analysis of high throughput reverse genetic assays using flow cytometry readouts. Genome Biol, 7:R77
     link to pubmed
     
     
155. Haase, B., Humphray, S. J., Lyer, S., Renner, M., Poustka, A., Mollenhauer, J., Leeb, T., (2006) Molecular characterization of the porcine deleted in malignant brain tumors 1 gene (DMBT1). Gene, 376:184-91
     link to pubmed
     
     
156. Gassler, N., Newrzella, D., Bohm, C., Lyer, S., Li, L., Sorgenfrei, O., van Laer, L., Sido, B., Mollenhauer, J., Poustka, A., Schirmacher, P., Gretz, N., (2006) Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine. Gut, 55:1084-9
     link to pubmed
     
     
157. Fleischer, S., Wiemann, S., Will, H., Hofmann, T. G., (2006) PML-associated repressor of transcription (PAROT), a novel KRAB-zinc finger repressor, is regulated through association with PML nuclear bodies. Exp Cell Res, 312:901-12
     link to pubmed
     
     
158. Finis, K., Sultmann, H., Ruschhaupt, M., Buness, A., Helmchen, B., Kuner, R., Gross, M. L., Fink, B., Schirmacher, P., Poustka, A., Berger, I., (2006) Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches. Arthritis Rheum, 54:1009-19
     link to pubmed
     
     
159. del Val, C., Kuryshev, V. Y., Glatting, K. H., Ernst, P., Hotz-Wagenblatt, A., Poustka, A., Suhai, S., Wiemann, S., (2006) CAFTAN: a tool for fast mapping, and quality assessment of cDNAs. BMC Bioinformatics, 7:473
     link to pubmed
     
     
160. Blasi, F., Bacchelli, E., Pesaresi, G., Carone, S., Bailey, A. J., Maestrini, E., (2006) Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection. Am J Med Genet B Neuropsychiatr Genet, 141:220-1
     link to pubmed
     
     
161. Blasi, F., Bacchelli, E., Carone, S., Toma, C., Monaco, A. P., Bailey, A. J., Maestrini, E., (2006) SLC25A12 and CMYA3 gene variants are not associated with autism in the IMGSAC multiplex family sample. Eur J Hum Genet, 14:123-6
     link to pubmed
     
     
162. Barth, A. S., Kuner, R., Buness, A., Ruschhaupt, M., Merk, S., Zwermann, L., Kaab, S., Kreuzer, E., Steinbeck, G., Mansmann, U., Poustka, A., Nabauer, M., Sultmann, H., (2006) Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies. J Am Coll Cardiol, 48:1610-7
     link to pubmed
     
     
163. Arlt, D., Sahin, O., Korf, U., Loebke, C., Beissbarth, T., Hahne, F., Wiemann, S., Poustka, A., (2006) Modeling breast cell cycle regulation - overcoming drug resistance. Conf Proc IEEE Eng Med Biol Soc, 1:40-3
     link to pubmed
     
     
164. Wittig, R., Salowsky, R., Blaich, S., Lyer, S., Maa, J. S., Muller, O., Mollenhauer, J., Poustka, A., (2005) Multiplex reverse transcription-polymerase chain reaction combined with on-chip electrophoresis as a rapid screening tool for candidate gene sets. Electrophoresis, 26:1687-91
     link to pubmed
     
     
165. Wiemann, S., Kolb-Kokocinski, A., Poustka, A., (2005) Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes. BMC Biol, 3:16
     link to pubmed
     
     
166. Sultmann, H., von Heydebreck, A., Huber, W., Kuner, R., Buness, A., Vogt, M., Gunawan, B., Vingron, M., Fuzesi, L., Poustka, A., (2005) Gene expression in kidney cancer is associated with cytogenetic abnormalities, metastasis formation, and patient survival. Clin Cancer Res, 11:646-55
     link to pubmed
     
     
167. Schlomm, T., Luebke, A. M., Sultmann, H., Hellwinkel, O. J., Sauer, U., Poustka, A., David, K. A., Chun, F. K., Haese, A., Graefen, M., Erbersdobler, A., Huland, H., (2005) Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis. Int J Oncol, 27:713-20
     link to pubmed
     
     
168. Ross, M. T., Grafham, D. V., Coffey, A. J., Scherer, S., McLay, K., Muzny, D., Platzer, M., Howell, G. R., Burrows, C., Bird, C. P., Frankish, A., Lovell, F. L., Howe, K. L., Ashurst, J. L., Fulton, R. S., Sudbrak, R., Wen, G., Jones, M. C., Hurles, M. E., Andrews, T. D., Scott, C. E., Searle, S., Ramser, J., Whittaker, A., Deadman, R., Carter, N. P., Hunt, S. E., Chen, R., Cree, A., Gunaratne, P., Havlak, P., Hodgson, A., Metzker, M. L., Richards, S., Scott, G., Steffen, D., Sodergren, E., Wheeler, D. A., Worley, K. C., Ainscough, R., Ambrose, K. D., Ansari-Lari, M. A., Aradhya, S., Ashwell, R. I., Babbage, A. K., Bagguley, C. L., Ballabio, A., Banerjee, R., Barker, G. E., Barlow, K. F., Barrett, I. P., Bates, K. N., Beare, D. M., Beasley, H., Beasley, O., Beck, A., Bethel, G., Blechschmidt, K., Brady, N., Bray-Allen, S., Bridgeman, A. M., Brown, A. J., Brown, M. J., Bonnin, D., Bruford, E. A., Buhay, C., Burch, P., Burford, D., Burgess, J., Burrill, W., Burton, J., Bye, J. M., Carder, C., Carrel, L., Chako, J., Chapman, J. C., Chavez, D., Chen, E., Chen, G., Chen, Y., Chen, Z., Chinault, C., Ciccodicola, A., Clark, S. Y., Clarke, G., Clee, C. M., Clegg, S., Clerc-Blankenburg, K., Clifford, K., Cobley, V., Cole, C. G., Conquer, J. S., Corby, N., Connor, R. E., David, R., Davies, J., Davis, C., Davis, J., Delgado, O., Deshazo, D., Dhami, P., Ding, Y., Dinh, H., Dodsworth, S., Draper, H., Dugan-Rocha, S., Dunham, A., Dunn, M., Durbin, K. J., Dutta, I., Eades, T., Ellwood, M., Emery-Cohen, A., Errington, H., Evans, K. L., Faulkner, L., Francis, F., Frankland, J., Fraser, A. E., Galgoczy, P., Gilbert, J., Gill, R., Glockner, G., Gregory, S. G., Gribble, S., Griffiths, C., Grocock, R., Gu, Y., Gwilliam, R., Hamilton, C., Hart, E. A., Hawes, A., Heath, P. D., Heitmann, K., Hennig, S., Hernandez, J., Hinzmann, B., Ho, S., Hoffs, M., Howden, P. J., Huckle, E. J., Hume, J., Hunt, P. J., Hunt, A. R., Isherwood, J., Jacob, L., Johnson, D., Jones, S., de Jong, P. J., Joseph, S. S., Keenan, S., Kelly, S., Kershaw, J. K., Khan, Z., Kioschis, P., Klages, S., Knights, A. J., Kosiura, A., Kovar-Smith, C., Laird, G. K., Langford, C., Lawlor, S., Leversha, M., Lewis, L., Liu, W., Lloyd, C., Lloyd, D. M., Loulseged, H., Loveland, J. E., Lovell, J. D., Lozado, R., Lu, J., Lyne, R., Ma, J., Maheshwari, M., Matthews, L. H., McDowall, J., McLaren, S., McMurray, A., Meidl, P., Meitinger, T., Milne, S., Miner, G., Mistry, S. L., Morgan, M., Morris, S., Muller, I., Mullikin, J. C., Nguyen, N., Nordsiek, G., Nyakatura, G., O'Dell C, N., Okwuonu, G., Palmer, S., Pandian, R., Parker, D., Parrish, J., Pasternak, S., Patel, D., Pearce, A. V., Pearson, D. M., Pelan, S. E., Perez, L., Porter, K. M., Ramsey, Y., Reichwald, K., Rhodes, S., Ridler, K. A., Schlessinger, D., Schueler, M. G., Sehra, H. K., Shaw-Smith, C., Shen, H., Sheridan, E. M., Shownkeen, R., Skuce, C. D., Smith, M. L., Sotheran, E. C., Steingruber, H. E., Steward, C. A., Storey, R., Swann, R. M., Swarbreck, D., Tabor, P. E., Taudien, S., Taylor, T., Teague, B., Thomas, K., Thorpe, A., Timms, K., Tracey, A., Trevanion, S., Tromans, A. C., d'Urso, M., Verduzco, D., Villasana, D., Waldron, L., Wall, M., Wang, Q., Warren, J., Warry, G. L., Wei, X., West, A., Whitehead, S. L., Whiteley, M. N., Wilkinson, J. E., Willey, D. L., Williams, G., Williams, L., Williamson, A., Williamson, H., Wilming, L., Woodmansey, R. L., Wray, P. W., Yen, J., Zhang, J., Zhou, J., Zoghbi, H., Zorilla, S., Buck, D., Reinhardt, R., Poustka, A., Rosenthal, A., Lehrach, H., Meindl, A., Minx, P. J., Hillier, L. W., Willard, H. F., Wilson, R. K., Waterston, R. H., Rice, C. M., Vaudin, M., Coulson, A., Nelson, D. L., Weinstock, G., Sulston, J. E., Durbin, R., Hubbard, T., Gibbs, R. A., Beck, S., Rogers, J., Bentley, D. R., (2005) The DNA sequence of the human X chromosome. Nature, 434:325-37
     link to pubmed
     
     
169. Neubrand, V. E., Will, R. D., Mobius, W., Poustka, A, Wiemann, S, Schu, P., Dotti, C. G., Pepperkok, R., Simpson, A. J., (2005) gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking. EMBO Journal, 24:1122-1133
     link to pubmed
     
     
170. Michaelovsky, E., Frisch, A., Leor, S., Stein, D., Danziger, Y., Carel, C., Fennig, S., Mimouni, M., Klauck, S. M., Benner, A., Poustka, A., Apter, A., Weizman, A., (2005) Haplotype analysis of the COMT-ARVCF gene region in Israeli anorexia nervosa family trios. Am J Med Genet B Neuropsychiatr Genet, :
     link to pubmed
     
     
171. Korf, U., Wiemann, S., (2005) Protein microarrays as a discovery tool for studying protein-protein interactions. Expert Rev Proteomics, 2:13-26
     link to pubmed
     
     
172. Korf, U., Kohl, T., van der Zandt, H., Zahn, R., Schleeger, S., Ueberle, B., Wandschneider, S., Bechtel, S., Schnolzer, M., Ottleben, H., Wiemann, S., Poustka, A., (2005) Large-scale protein expression for proteome research. Proteomics, :
     link to pubmed
     
     
173. Karenko, L., Hahtola, S., Paivinen, S., Karhu, R., Syrja, S., Kahkonen, M., Nedoszytko, B., Kytola, S., Zhou, Y., Blazevic, V., Pesonen, M., Nevala, H., Nupponen, N., Sihto, H., Krebs, I., Poustka, A., Roszkiewicz, J., Saksela, K., Peterson, P., Visakorpi, T., Ranki, A., (2005) Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue. Cancer Res, 65:8101-10
     link to pubmed
     
     
174. Hawtin, P., Hardern, I., Wittig, R., Mollenhauer, J., Poustka, A., Salowsky, R., Wulff, T., Rizzo, C., Wilson, B., (2005) Utility of lab-on-a-chip technology for high-throughput nucleic acid and protein analysis. Electrophoresis, 26:3674-3681
     link to pubmed
     
     
175. Guilleaume, B., Buness, A., Schmidt, C., Klimek, F., Moldenhauer, G., Huber, W., Arlt, D., Korf, U., Wiemann, S., Poustka, A., (2005) Systematic comparison of surface coatings for protein microarrays. Proteomics, 5:4705-4712
     link to pubmed
     
     
176. End, C., Lyer, S., Renner, M., Stahl, C., Ditzer, J., Holloschi, A., Kuhn, H. M., Flammann, H. T., Poustka, A., Hafner, M., Mollenhauer, J., Kioschis, P., (2005) Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1. Protein Expr Purif, 41:275-86
     link to pubmed
     
     
177. Buness, A., Huber, W., Steiner, K., Sultmann, H., Poustka, A., (2005) arrayMagic: two-colour cDNA microarray quality control and preprocessing. Bioinformatics, 21:554-6
     link to pubmed
     
     
178. Bonora, E., Lamb, J. A., Barnby, G., Sykes, N., Moberly, T., Beyer, K. S., Klauck, S. M., Poustka, F., Bacchelli, E., Blasi, F., Maestrini, E., Battaglia, A., Haracopos, D., Pedersen, L., Isager, T., Eriksen, G., Viskum, B., Sorensen, E. U., Brondum-Nielsen, K., Cotterill, R., Engeland, H., Jonge, M., Kemner, C., Steggehuis, K., Scherpenisse, M., Rutter, M., Bolton, P. F., Parr, J. R., Poustka, A., Bailey, A. J., Monaco, A. P., (2005) Mutation screening and association analysis of six candidate genes for autism on chromosome 7q. Eur J Hum Genet, 13:198-207
     link to pubmed
     
     
179. Arlt, D., Huber, W., Liebel, U., Schmidt, C., Majety, M., Sauermann, M., Rosenfelder, H., Bechtel, S., Mehrle, A., Bannasch, D., Schupp, I., Seiler, M., Simpson, J. C., Hahne, F., Moosmayer, P., Ruschhaupt, M., Guilleaume, B., Wellenreuther, R., Pepperkok, R., Sultmann, H., Poustka, A., Wiemann, S., (2005) Functional Profiling: From Microarrays via Cell-Based Assays to Novel Tumor Relevant Modulators of the Cell Cycle. Cancer Res, 65:7733-42
     link to pubmed
     
     
180. Wiemann, S., Arlt, D., Huber, W., Wellenreuther, R., Schleeger, S., Mehrle, A., Bechtel, S., Sauermann, M., Korf, U., Pepperkok, R., Sultmann, H., Poustka, A., (2004) From ORFeome to Biology: A Functional Genomics Pipeline. Genome Res, 14:2136-44
     link to pubmed
     
     
181. Wellenreuther, R., Schupp, I., The German cDNA Consortium, Poustka, A., Wiemann, S., (2004) SMART amplification combined with cDNA size fractionation in order to obtain large full-length clones. BMC Genomics, 5:36
     link to pubmed
     
     
182. Sultmann, H., Poustka, A., (2004) Recent advances in transcription profiling of human cancer. Curr Opin Mol Ther, 6:593-9
     link to pubmed
     
     
183. Starkuviene, V., Liebel, U., Simpson, J. C., Erfle, H., Poustka, A., Wiemann, S., Pepperkok, R., (2004) High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic. Genome Res, 14:1948-56
     link to pubmed
     
     
184. Schneider, J., Buness, A., Huber, W., Volz, J., Kioschis, P., Hafner, M., Poustka, A., Sultmann, H., (2004) Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments. BMC Genomics, 5:29
     link to pubmed
     
     
185. Sasaki, M., Tsuneyama, K., Saito, T., Kataoka, H., Mollenhauer, J., Poustka, A., Nakanuma, Y., (2004) Site-characteristic expression and induction of trefoil factor family 1, 2 and 3 and malignant brain tumor-1 in normal and diseased intrahepatic bile ducts relates to biliary pathophysiology. Liver Int, 24:29-37
     link to pubmed
     
     
186. Ruschhaupt, M, Huber, W, Poustka, A, Mansmann, U, (2004) A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks. Statistical Applications in Genetics and Molecular Biology, 3:Article 37
     link to pubmed
     
     
187. Poustka, A. J., Kuhn, A., Radosavljevic, V., Wellenreuther, R., Lehrach, H., Panopoulou, G., (2004) On the origin of the chordate central nervous system: expression of onecut in the sea urchin embryo. Evol Dev, 6:227-36
     link to pubmed
     
     
188. Mollenhauer, J., Helmke, B., Medina, D., Bergmann, G., Gassler, N., Muller, H., Lyer, S., Diedrichs, L., Renner, M., Wittig, R., Blaich, S., Hamann, U., Madsen, J., Holmskov, U., Bikker, F., Ligtenberg, A., Carlen, A., Olsson, J., Otto, H. F., O'Malley, B., Poustka, A., (2004) Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chromosomes Cancer, 39:185-94
     link to pubmed
     
     
189. Kontou, M., Will, R. D., Adelfalk, C., Wittig, R., Poustka, A., Hirsch-Kauffmann, M., Schweiger, M., (2004) Thioredoxin, a regulator of gene expression. Oncogene, 23:2146-52
     link to pubmed
     
     
190. Imanishi, T., Itoh, T., Suzuki, Y., O'Donovan, C., Fukuchi, S., Koyanagi, K. O., Barrero, R. A., Tamura, T., Yamaguchi-Kabata, Y., Tanino, M., Yura, K., Miyazaki, S., Ikeo, K., Homma, K., Kasprzyk, A., Nishikawa, T., Hirakawa, M., Thierry-Mieg, J., Thierry-Mieg, D., Ashurst, J., Jia, L., Nakao, M., Thomas, M. A., Mulder, N., Karavidopoulou, Y., Jin, L., Kim, S., Yasuda, T., Lenhard, B., Eveno, E., Yamasaki, C., Takeda, J., Gough, C., Hilton, P., Fujii, Y., Sakai, H., Tanaka, S., Amid, C., Bellgard, M., Bonaldo Md Mde, F., Bono, H., Bromberg, S. K., Brookes, A. J., Bruford, E., Carninci, P., Chelala, C., Couillault, C., Souza, S. J., Debily, M. A., Devignes, M. D., Dubchak, I., Endo, T., Estreicher, A., Eyras, E., Fukami-Kobayashi, K., R. Gopinath G, Graudens, E., Hahn, Y., Han, M., Han, Z. G., Hanada, K., Hanaoka, H., Harada, E., Hashimoto, K., Hinz, U., Hirai, M., Hishiki, T., Hopkinson, I., Imbeaud, S., Inoko, H., Kanapin, A., Kaneko, Y., Kasukawa, T., Kelso, J., Kersey, P., Kikuno, R., Kimura, K., Korn, B., Kuryshev, V., Makalowska, I., Makino, T., Mano, S., Mariage-Samson, R., Mashima, J., Matsuda, H., Mewes, H. W., Minoshima, S., Nagai, K., Nagasaki, H., Nagata, N., Nigam, R., Ogasawara, O., Ohara, O., Ohtsubo, M., Okada, N., Okido, T., Oota, S., Ota, M., Ota, T., Otsuki, T., Piatier-Tonneau, D., Poustka, A., Ren, S. X., Saitou, N., Sakai, K., Sakamoto, S., Sakate, R., Schupp, I., Servant, F., Sherry, S., Shiba, R., Shimizu, N., Shimoyama, M., Simpson, A. J., Soares, B., Steward, C., Suwa, M., Suzuki, M., Takahashi, A., Tamiya, G., Tanaka, H., Taylor, T., Terwilliger, J. D., Unneberg, P., Veeramachaneni, V., Watanabe, S., Wilming, L., Yasuda, N., Yoo, H. S., Stodolsky, M., Makalowski, W., Go, M., Nakai, K., Takagi, T., Kanehisa, M., Sakaki, Y., Quackenbush, J., Okazaki, Y., Hayashizaki, Y., Hide, W., Chakraborty, R., Nishikawa, K., Sugawara, H., Tateno, Y., Chen, Z., Oishi, M., Tonellato, P., Apweiler, R., Okubo, K., Wagner, L., Wiemann, S., Strausberg, R. L., Isogai, T., Auffray, C., Nomura, N., Gojobori, T., Sugano, S., (2004) Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol, 2:856-875
     link to pubmed
     
     
191. Huber, W., Gentleman, R., (2004) matchprobes: a Bioconductor package for the sequence-matching of microarray probe elements. Bioinformatics, 20:1651-1652
     link to pubmed
     
     
192. Helmke, B. M., Mollenhauer, J., Herold-Mende, C., Benner, A., Thome, M., Gassler, N., Wahl, W., Lyer, S., Poustka, A., Otto, H. F., Deichmann, M., (2004) BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level. Gastroenterology, 127:1815-20
     link to pubmed
     
     
193. Haller, F., Kulle, B., Schwager, S., Gunawan, B., von Heydebreck, A., Sultmann, H., Fuzesi, L., (2004) Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization. Anal Biochem, 335:1-9
     link to pubmed
     
     
194. Gassler, N., Kopitz, J., Tehrani, A., Ottenwalder, B., Schnolzer, M., Kartenbeck, J., Lyer, S., Autschbach, F., Poustka, A., Otto, H. F., Mollenhauer, J., (2004) Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine. J Pathol, 202:188-96
     link to pubmed
     
     
195. del Val, C., Mehrle, A., Falkenhahn, M., Seiler, M., Glatting, K. H., Poustka, A., Suhai, S., Wiemann, S., (2004) High-throughput protein analysis integrating bioinformatics and experimental assays. Nucleic Acids Res, 32:742-8
     link to pubmed
     
     
196. D'Adamo, P., Bacchelli, E., Blasi, F., Lipp, H. P., Toniolo, D., Maestrini, E., and the Molecular Genetic Study of Autism Consortium (IMGSAC), (2004) DNA variants in the human RAB3A gene are not associated with autism. Genes Brain Behav, 3:123-4
     link to pubmed
     
     
197. Braidotti, P., Nuciforo, P. G., Mollenhauer, J., Poustka, A., Pellegrini, C., Moro, A., Bulfamante, G., Coggi, G., Bosari, S., Pietra, G. G., (2004) DMBT1 expression is down-regulated in breast cancer. BMC Cancer, 4:46
     link to pubmed
     
     
198. Bikker, F. J., Van Der Wal, J. E., Ligtenberg, A. J., Mollenhauer, J., De Blieck-Hogervorst, J. M., Van Der Waal, I., Poustka, A., Nieuw Amerongen, A. V., (2004) Salivary Agglutinin/DMBT1(SAG) Expression is Up-regulated in the Presence of Salivary Gland Tumors. J Dent Res, 83:567-71
     link to pubmed
     
     
199. Bikker, F. J., Ligtenberg, A. J., End, C., Renner, M., Blaich, S., Lyer, S., Wittig, R., Van 't Hof, W., Veerman, E. C., Nazmi, K., De Blieck-Hogervorst, J. M., Kioschis, P., Nieuw Amerongen, A. V., Poustka, A., Mollenhauer, J., (2004) Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains. J Biol Chem, :
     link to pubmed
     
     
200. Bannasch, D., Mehrle, A., Glatting, K. H., Pepperkok, R., Poustka, A., Wiemann, S., (2004) LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system. Nucleic Acids Res, 32 Database issue:D505-8
     link to pubmed
     
     
201. Wiemann, S., Mehrle, A., Bechtel, S., Wellenreuther, R., Pepperkok, R., Poustka, A., The German cDNA Consortium, (2003) cDNAs in functional genomics and proteomics: The German cDNA Consortium. C.R.Biologies, 326:1003-1009
     link to pubmed
     
     
202. Wiemann, S., Bechtel, S., Bannasch, D., Pepperkok, R., Poustka, A., The German cDNA Network, (2003) The German cDNA Network: cDNAs, functional genomics and proteomics. J Struct Funct Genom, 4:87-96
     link to pubmed
     
     
203. Wellenreuther, R., Bechtel, S., (2003) Identifying transcribed sequences and beyond. Genome Biol, 4:306
     link to pubmed
     
     
204. Straub, B. K., Boda, J., Kuhn, C., Schnoelzer, M., Korf, U., Kempf, T., Spring, H., Hatzfeld, M., Franke, W. W., (2003) A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. J Cell Sci, 116:4985-95
     link to pubmed
     
     
205. Schumann, G., Rujescu, D., Szegedi, A., Singer, P., Wiemann, S., Wellek, S., Giegling, I., Klawe, C., Anghelescu, I., Heinz, A., Spanagel, R., Mann, K., Henn, F. A., Dahmen, N., (2003) No association of alcohol dependence with a NMDA-receptor 2B gene variant. Mol Psychiatry, 8:11-12
     link to pubmed
     
     
206. Schumann, G., Rujescu, D., Kissling, C., Soyka, M., Dahmen, N., Preuss, U. W., Wiemann, S, Müller, A., Wellek, S., Lascorz, J., Bondy, B., Giegling, I., Anghelescu, I., Cowen, M. S., Poustka, A, Spanagel, R., Mann, K., Henn, F. A., Szegedi, A., (2003) Analysis of genetic variations of Protein Tyrosine Kinase fyn and their as-sociation with alcohol dependence in two independent cohorts. Biol Psychiatry, 54:1422-1426
     link to pubmed
     
     
207. Sasaki, M., Huang, S. F., Chen, M. F., Jan, Y. Y., Yeh, T. S., Ishikawa, A., Mollenhauer, J., Poustka, A., Tsuneyama, K., Nimura, Y., Oda, K., Nakanuma, Y., (2003) Decrease of deleted in malignant brain tumour-1 (DMBT-1) expression is a crucial late event in intrahepatic cholangiocarcinoma. Histopathology, 43:340-6
     link to pubmed
     
     
208. Sasaki, M., Huang, S. F., Chen, M. F., Jan, Y. Y., Yeh, T. S., Ishikawa, A., Mollenhauer, J., Poustka, A., Tsuneyama, K., Nimura, Y., Oda, K., Nakanuma, Y., (2003) Expression of deleted in malignant brain tumor-1 (DMBT1) molecule in biliary epithelium is augmented in hepatolithiasis: possible participation in lithogenesis. Dig Dis Sci, 48:1234-1240
     link to pubmed
     
     
209. Mollenhauer, J., Deichmann, M., Helmke, B., Muller, H., Kollender, G., Holmskov, U., Ligtenberg, T., Krebs, I., Wiemann, S., Bantel-Schaal, U., Madsen, J., Bikker, F., Klauck, S. M., Otto, H. F., Moldenhauer, G., Poustka, A., (2003) Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer. Int J Cancer, 105:149-157
     link to pubmed
     
     
210. Madsen, J., Tornoe, I., Nielsen, O., Lausen, M., Krebs, I., Mollenhauer, J., Kollender, G., Poustka, A., Skjodt, K., Holmskov, U., (2003) CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D. Eur J Immunol, 33:2327-2336
     link to pubmed
     
     
211. Liebel, U., Starkuviene, V., Erfle, H., Simpson, J. C., Poustka, A., Wiemann, S., Pepperkok, R., (2003) A microscope-based screening platform for large-scale functional protein analysis in intact cells. FEBS Lett, 554:394-398
     link to pubmed
     
     
212. Langer, C., Gunawan, B., Schuler, P., Huber, W., Füzesi, L., Becker, H., (2003) Prognostic factors influencing surgical management and outcome of gastrointestinal stromal tumors. Br J Surg, 90:332-339
     link to pubmed
     
     
213. Huber, W., von Heydebreck, A., Vingron, M., (2003) Analysis of microarray gene expression data. In: Handbook of Statistical Genetics, :162-187
     
     
     
214. Huber, W., von Heydebreck, A., Sultmann, H., Poustka, A., Vingron, M., (2003) Parameter estimation for the calibration and variance stabilization of microarray data. Stat Appl Genet Mol Biol, 2:Article 3
     
     
     
215. Heiss, N. S., Poustka, A, (2003) Dyskeratosis Congenita. In: Chromosomal instability and aging: basic science and clinical implication, :
     
     
     
216. Gunawan, B., von Heydebreck, A., Huber, W., Vingron, M., Füzesi, L., (2003) Cytogenetic and Morphologic Typing of 58 Papillary Renal Cell Carcinomas: Evidence for a Cytogeneitc Evolution of Type 2 from Type 1 Tumors. Cancer Res, 63:6200-6205
     link to pubmed
     
     
217. Broders, O., Breitling, F., Dubel, S., (2003) Hyperphage. Improving antibody presentation in phage display. Methods Mol Biol, 205:295-302
     link to pubmed
     
     
218. Bonora, E., Beyer, K. S., Lamb, J.A., Parr, J.R., Klauck, S. M., Benner, A., Paolucci, M., Abbot, A., Ragoussis, I., Poustka, A., Bailey, A., Monaco, A.P., IMGSAC, (2003) Analysis of reelin as a candidate gene for autism. Mol Psychiatry, 8:885-892
     link to pubmed
     
     
219. Bacchelli, E., Blasi, F., Biondolillo, M, Lamb, J.A., Bonora, E., Barnby, G., Parr, J., Beyer, K. S., Klauck, S. M., Poustka, A., Bailey, A., Monaco, A.P., Maestrini, E., IMGSAC, (2003) Screening of nine candidate genes for autism on chromosome 2q reveals rare non-sysnonymous variants in the cAMP-GEFII gene. Mol Psychiatry, 8:916 -924
     link to pubmed
     
     
220. Apic, G., Huber, W., Teichmann, S. A., (2003) Multi-domain protein families and domain pairs: comparison with known structures and a random model of domain recombination. J Struct Funct Genom, 4:67-78
     link to pubmed
     
     
221. Wittig, R., Nessling, M., Will, R. D., Mollenhauer, J., Salowsky, R., Munstermann, E., Schick, M., Helmbach, H., Gschwendt, B., Korn, B., Kioschis, P., Lichter, P., Schadendorf, D., Poustka, A., (2002) Candidate genes for cross-resistance against DNA-damaging drugs. Cancer Res, 62:6698-705
     link to pubmed
     
     
222. von Heydebreck, A., Huber, W., Poustka, A., Vingron, M., (2002) Variance stabilization and robust normalization for microarray gene expression data. Proceeding in Computational Statistics, :623-628
     
     
     
223. Schumann, G., Rujescu D., Szegedi, A., Singer, P., Wiemann, S., Welek, S., Giegling, I., Klawe C., Anghelescu I., Heinz, A., Spanagel, R., Mann, K., Henn, F.A., Dahmen, N., (2002) Alcohol dependence is associated with NMDN receptor 2B gene variant. Eur Psychiatry, 17:212
     link to pubmed
     
     
224. Salowsky, R., Heiss, N. S., Benner, A., Wittig, R., Poustka, A., (2002) Basal transcription activity of the dyskeratosis congenita gene is mediated by Sp1 and Sp3 and a patient mutation in a Sp1 binding site is associated with decreased promoter activity. Gene, 293:9-19
     link to pubmed
     
     
225. Poland, J., Sinha, P., Siegert, A., Schnolzer, M., Korf, U., Hauptmann, S., (2002) Comparison of protein expression profiles between monolayer and spheroid cell culture of HT-29 cells revealed fragmentation of CK18 in three-dimensional cell culture. Electrophoresis, 23:1174-84
     link to pubmed
     
     
226. Newbury, D.F., Bonora, E., Lamb, J.A., Fisher, S.E., Lai, C., Baird, G., Jannoun, L., Solonims, V., Stott, C.M., Merricks, J. , Bolton P,F., Bailey A.J., Monaco, A.P., IMGSAC, (2002) FOXP2 is not a major susceptibility gene for autism or specific language impairment.. Am J Hum Genet, 70:1318-1327
     link to pubmed
     
     
227. Mueller, W., Mollenhauer, J., Stockhammer, F., Poustka, A., von Deimling, A., (2002) Rare mutations of the DMBT1 gene in human astrocytic gliomas. Oncogene, 21:5956-9
     link to pubmed
     
     
228. Mollenhauer, J., Muller, H., Kollender, G., Lyer, S., Diedrichs, L., Helmke, B., Holmskov, U., Ligtenberg, T., Herbertz, S., Krebs, I., Madsen, J., Bikker, F., Schmitt, L., Wiemann, S., Scheurlen, W., Otto, H. F., von Deimling, A., Poustka, A., (2002) The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer. Genes Chromosomes Cancer, 35:242-55
     link to pubmed
     
     
229. Mollenhauer, J., Helmke, B., Muller, H., Kollender, G., Lyer, S., Diedrichs, L., Holmskov, U., Ligtenberg, T., Herbertz, S., Krebs, I., Wiemann, S., Madsen, J., Bikker, F., Schmitt, L., Otto, H. F., Poustka, A., (2002) Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas. Genes Chromosomes Cancer, 35:164-9
     link to pubmed
     
     
230. Mollenhauer, J., Helmke, B., Muller, H., Kollender, G., Krebs, I., Wiemann, S., Holmskov, U., Madsen, J., Otto, H. F., Poustka, A., (2002) An integrative model on the role of DMBT1 in epithelial cancer. Cancer Detect Prev, 26:266-74
     link to pubmed
     
     
231. Klauck, S. M., Lindsay, S., Beyer, K. S., Splitt, M., Burn, J., Poustka, A., (2002) A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome. Am J Hum Genet, 70:1034-7
     link to pubmed
     
     
232. Huber, W., Von Heydebreck, A., Sultmann, H., Poustka, A., Vingron, M., (2002) Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics, 18 Suppl 1:S96-S104
     link to pubmed
     
     
233. Huber, W., Boer, J. M., von Heydebreck, A., Gunawan, B., Vingron, M., Fuzesi, L., Poustka, A., Sultmann, H., (2002) Transcription profiling of renal cell carcinoma. Verh Dtsch Ges Pathol, 86:153-64
     link to pubmed
     
     
234. Heiss, N. S., Poustka, A., Dyskerin (DKC1 Gene), (2002) DKC1 Gene. Encyclopedia of Molecular Medicine, :1121 - 1126
     
     
     
235. Deichmann, M., Mollenhauer, J., Helmke, B., Thome, M., Hartschuh, W., Poustka, A., Naher, H., (2002) Analysis of losses of heterozygosity of the candidate tumour suppressor gene DMBT1 in melanoma resection specimens. Oncology, 63:166-72
     link to pubmed
     
     
236. Coy, J. F., Wiemann, S., Bechmann, I., Bachner, D., Nitsch, R., Kretz, O., Christiansen, H., Poustka, A., (2002) Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene, 290:73-94
     link to pubmed
     
     
237. Copley, L. M., Zhao, W. D., Kopacz, K., Herman, G. E., Kioschis, P., Poustka, A., Taudien, S., Platzer, M., (2002) Exclusion of mutations in the MTMR1 gene as a frequent cause of X-linked myotubular myopathy. Am J Med Genet, 107:256-8
     link to pubmed
     
     
238. Bonora, E., Bacchelli, E., Levy, R.E.., Blasi, F., Marlow, A., Monaco, A.P., Maestrini, E., IMGSAC, (2002) Mutation screening and imprinting analysis of four candidate genes for autism in the 7q32 region. Mol Psychiatry, 7:289-301
     link to pubmed
     
     
239. Bikker, F. J., Ligtenberg, A. J., Nazmi, K., Veerman, E. C., van't Hof, W., Bolscher, J. G., Poustka, A., Nieuw Amerongen, A. V., Mollenhauer, J., (2002) Identification of the bacteria-binding peptide domain on salivary agglutinin (gp-340/DMBT1), a member of the scavenger receptor cysteine-rich superfamily. J Biol Chem, 277:32109-15
     link to pubmed
     
     
240. Beyer, K. S., Klauck, S. M., Benner, A., Poustka, F., Poustka, A., (2002) Association studies of the HOPA dodecamer duplication variant in different subtypes of autism. Am J Med Genet, 114:110-5
     link to pubmed
     
     
241. Beyer, K. S., Blasi, F., Bacchelli, E., Klauck, S. M., Maestrini, E., Poustka, A., (2002) Mutation analysis of the coding sequence of the MECP2 gene in infantile autism. Hum Genet, 111:305-9
     link to pubmed
     
     
242. Aradhya, S., Woffendin, H., Bonnen, P., Heiss, N. S., Yamagata, T., Esposito, T., Bardaro, T., Poustka, A., D'Urso, M., Kenwrick, S., Nelson, D. L., (2002) Physical and genetic characterization reveals a pseudogene, an evolutionary junction, and unstable loci in distal Xq28. Genomics, 79:31-40
     link to pubmed
     
     
243. Wirth, J., Back, E. , Hüttenhofer, A., Nothwang, H.G. , Lich, C., Groß, S., Menzel, C. Schnizel, A., Kioschis, P., Tommerup, N., Ropers, H.H., Horsthemke, B., Buiting, K., (2001) A transcriptional breakpoint cluster disrupts the newly defined 3' end of the SNURF-SNRPN transcription unit on chromosome 15. Hum Mol Genet, 10:201-210
     link to pubmed
     
     
244. Wiemann, S., Weil, B., Wellenreuther, R., Gassenhuber, J., Glassl, S., Ansorge, W., Böcher, M., Blöcker, H., Bauersachs, S., Blum, H., Lauber, J., Düsterhöft, A., Beyer, A., Köhrer, K., Strack, N., Mewes, H. W., Ottenwälder, B., Obermaier, B., Tampe, J., Heubner, D., Wambutt, R., Korn, B., Klein, M., Poustka, A., (2001) Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Genome Res, 11:422-35
     link to pubmed
     
     
245. von Heydebreck, A., Huber, W., Poustka, A., Vingron, M., (2001) Identifying splits with clear separation: a new class discovery method for gene expression data. Bioinformatics, 17 Suppl 1:S107-14
     link to pubmed
     
     
246. Simpson, J. C., Neubrand, V. E., Wiemann, S., Pepperkok, R., (2001) Illuminating the human genome. Histochem Cell Biol, 115:23-9
     link to pubmed
     
     
247. Seranski, P., Hoff, C., Radelof, U., Hennig, S., Reinhardt, R., Schwartz, C. E., Heiss, N. S., Poustka, A., (2001) RAI1 is a novel polyglutamine encoding gene that is deleted in Smith-Magenis syndrome patients. Gene, 270:69-76
     link to pubmed
     
     
248. Rondot, S., Koch, J., Breitling, F., Dubel, S., (2001) A helper phage to improve single-chain antibody presentation in phage display. Nat Biotechnol, 19:75-8
     link to pubmed
     
     
249. Pepperkok, R., Simpson, J. C., Wiemann, S., (2001) Being in the right location at the right time. Genome Biol, 2:REVIEWS1024
     link to pubmed
     
     
250. Nadeau, J. H., Balling, R., Barsh, G., Beier, D., Brown, S. D., Bucan, M., Camper, S., Carlson, G., Copeland, N., Eppig, J., Fletcher, C., Frankel, W. N., Ganten, D., Goldowitz, D., Goodnow, C., Guenet, J. L., Hicks, G., de Angelis, M. H., Jackson, I., Jacob, H. J., Jenkins, N., Johnson, D., Justice, M., Kay, S., Kingsley, D., Lehrach, H., Magnuson, T., Meisler, M., Poustka, A., Rinchik, E. M., Rossant, J., Russell, L. B., Schimenti, J., Shiroishi, T., Skarnes, W. C., Soriano, P., Stanford, W., Takahashi, J. S., Wurst, W., Zimmer, A., (2001) Sequence interpretation. Functional annotation of mouse genome sequences. Science, 291:1251-5
     link to pubmed
     
     
251. Mollenhauer, J., Herbertz, S., Helmke, B., Kollender, G., Krebs, I., Madsen, J., Holmskov, U., Sorger, K., Schmitt, L., Wiemann, S., Otto, H. F., Grone, H. J., Poustka, A., (2001) Deleted in Malignant Brain Tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer. Cancer Res, 61:8880-6
     link to pubmed
     
     
252. McPherson, J. D., Marra, M., Hillier, L., Waterston, R. H., Chinwalla, A., Wallis, J., Sekhon, M., Wylie, K., Mardis, E. R., Wilson, R. K., Fulton, R., Kucaba, T. A., Wagner-McPherson, C., Barbazuk, W. B., Gregory, S. G., Humphray, S. J., French, L., Evans, R. S., Bethel, G., Whittaker, A., Holden, J. L., McCann, O. T., Dunham, A., Soderlund, C., Scott, C. E., Bentley, D. R., Schuler, G., Chen, H. C., Jang, W., Green, E. D., Idol, J. R., Maduro, V. V., Montgomery, K. T., Lee, E., Miller, A., Emerling, S., Kucherlapati,, Gibbs, R., Scherer, S., Gorrell, J. H., Sodergren, E., Clerc-Blankenburg, K., Tabor, P., Naylor, S., Garcia, D., de Jong, P. J., Catanese, J. J., Nowak, N., Osoegawa, K., Qin, S., Rowen, L., Madan, A., Dors, M., Hood, L., Trask, B., Friedman, C., Massa, H., Cheung, V. G., Kirsch, I. R., Reid, T., Yonescu, R., Weissenbach, J., Bruls, T., Heilig, R., Branscomb, E., Olsen, A., Doggett, N., Cheng, J. F., Hawkins, T., Myers, R. M., Shang, J., Ramirez, L., Schmutz, J., Velasquez, O., Dixon, K., Stone, N. E., Cox, D. R., Haussler, D., Kent, W. J., Furey, T., Rogic, S., Kennedy, S., Jones, S., Rosenthal, A., Wen, G., Schilhabel, M., Gloeckner, G., Nyakatura, G., Siebert, R., Schlegelberger, B., Korenberg, J., Chen, X. N., Fujiyama, A., Hattori, M., Toyoda, A., Yada, T., Park, H. S., Sakaki, Y., Shimizu, N., Asakawa, S., Kawasaki, K., Sasaki, T., Shintani, A., Shimizu, A., Shibuya, K., Kudoh, J., Minoshima, S., Ramser, J., Seranski, P., Hoff, C., Poustka, A., Reinhardt, R., Lehrach, H., (2001) A physical map of the human genome. Nature, 409:934-41
     link to pubmed
     
     
253. International Molecular Genetic Study of Autism Consortium (IMGSAC), , Palfermann, S., Matthews, N., Turner, M. , Moore J. , Hervas, A. , Aubin, A., Wllace S., Michelotti, J., Wainhouse, D., Paul, A., Thompson, E., Gupta, R., Garner, C., Murin, M., Freitag, C., Ryder, N., Cottington, E., Parr, J., Pickles, A., Rutter, M., Bailey, A., Barnby, G., Lamb, J.A., Marlow, A., Scudder, P., Monaco, A.P., Baird, G., Cox, A., Docherty, Z., Warburton, P., Klauck. S.M., Beyer, K. S., Epp, S., Poustka, A., Brenner, A., et al., (2001) A genome wide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q and 16p. Am J Hum Genet, 69:570-581
     link to pubmed
     
     
254. Huber, W., von Heydebreck, A., Sültmann, H., Poustka, A., Vingron, M., (2001) Data preprocessing and quality control for DNA array expression profiling experiments.. Currents in Computational Molecular Biology, :181-182
     
     
     
255. Hoff, C., Mollenhauer, J., Waldau, B., Hamann, U., Poustka, A., (2001) Allelic imbalance and fine mapping of the 17p13.3 subregion in sporadic breast carcinomas. Cancer Genet Cytogenet, 129:145-9
     link to pubmed
     
     
256. Heiss, N. S., Megarbane, A., Klauck, S. M., Kreuz, F. R., Makhoul, E., Majewski, F., Poustka, A., (2001) One novel and two recurrent missense DKC1 mutations in patients with dyskeratosis congenita (DKC). Genet Couns, 12:129-36
     link to pubmed
     
     
257. Gunawan, B., Huber, W., Holtrup, M., von Heydebreck, A., Efferth, T., Poustka, A., Ringert, R. H., Jakse, G., Fuzesi, L., (2001) Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis. Cancer Res, 61:7731-8
     link to pubmed
     
     
258. Gotte, K., Riedel, F., Neubuer, J., Schafer, C., Coy, J., Hormann, K., (2001) The relationship between allelic imbalance on 17p, p53 overexpression in head and neck cancer. Int J Oncology, 19:331-336
     link to pubmed
     
     
259. Boer, J. M., Huber, W. K., Sultmann, H., Wilmer, F., von Heydebreck, A., Haas, S., Korn, B., Gunawan, B., Vente, A., Fuzesi, L., Vingron, M., Poustka, A., (2001) Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31,500-element cDNA array. Genome Res, 11:1861-70
     link to pubmed
     
     
260. Beyer, K. S., Klauck, S. M., Wiemann, S., Poustka, A., (2001) Construction of a physical map of an autism susceptibility region in 7q32.3-q33. Gene, 272:85-91
     link to pubmed
     
     
261. International Molecular Genetic Study of Autism Consortium (IMGSAC) , Palfermann, S., Matthews, N., Turner, M., Moore, J., Haervas, A., Aubin, A., Wallace, S., Michelotti, J., Wainhouse, D., Paul, A., Thompson, E., Murin, M., Gupta, R., Garner, C., Pickles, A., Rutter, M., Bailey, A., Lamb, J.A., Marlow, A., Scudder, P., Barnby, G., Monaco, A.P., Baird, G., Cox, A., Docherty, Z., Warburton, P., Green, E. D., Abbs, S.J., Le Couteur, A., McConachie, H.R., Klauck, S. M., Beyer, K. S., Epp, S., Poustka, A., Brenner, A., et al., (2001) Further characterization of the autism susceptibility locus AUTS 1 on chromosome 7q. Hum Mol Genet, 10:973-982
     link to pubmed
     
     
262. Yaghmai, R., Kimyai-Asadi, A., Rostamiani, K., Heiss, N. S., Poustka, A., Eyaid, W., Bodurtha, J., Nousari, H. C., Hamosh, A., Metzenberg, A., (2000) Overlap of dyskeratosis congenita with the Hoyeraal-Hreidarsson syndrome. J Pediatr, 136:390-3
     link to pubmed
     
     
263. von Deimling, A., Fimmers, R., Schmidt, M. C., Bender, B., Fassbender, F., Nagel, J., Jahnke, R., Kaskel, P., Duerr, E. M., Koopmann, J., Maintz, D., Steinbeck, S., Wick, W., Platten, M., Muller, D. J., Przkora, R., Waha, A., Blumcke, B., Wellenreuther, R., Meyer-Puttlitz, B., Schmidt, O., Mollenhauer, J., Poustka, A., Stangl, A. P., Lenartz, D., von Ammon, K., (2000) Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors. J Neuropathol Exp Neurol, 59:544-58
     link to pubmed
     
     
264. Thullner, S., Gesellchen, F., Wiemann, S., Pyerin, W., Kinzel, V., Bossemeyer, D., (2000) The protein kinase A catalytic subunit Cbeta2: molecular characterization and distribution of the splice variant. Biochem J, 351:123-32
     link to pubmed
     
     
265. Smahi, A., Courtois, G., Vabres, P., Yamaoka, S., Heuertz, S., Munnich, A., Israel, A., Heiss, N. S., Klauck, S. M., Kioschis, P., Wiemann, S., Poustka, A., Esposito, T., Bardaro, T., Gianfrancesco, F., Ciccodicola, A., D'Urso, M., Woffendin, H., Jakins, T., Donnai, D., Stewart, H., Kenwrick, S. J., Aradhya, S., Yamagata, T., Levy, M., Lewis, R. A., Nelson, D. L., (2000) Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature, 405:466-72
     link to pubmed
     
     
266. Simpson, J. C., Wellenreuther, R., Poustka, A., Pepperkok, R., Wiemann, S., (2000) Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Rep, 1:287-92
     link to pubmed
     
     
267. Schmiedl, A., Breitling, F., Winter, C. H., Queitsch, I., Dubel, S., (2000) Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli. J Immunol Methods, 242:101-14
     link to pubmed
     
     
268. Schmiedl, A., Breitling, F., Dubel, S., (2000) Expression of a bispecific dsFv-dsFv' antibody fragment in Escherichia coli. Protein Eng, 13:725-34
     link to pubmed
     
     
269. Reichwald, K., Thiesen, J., Wiehe, T., Weitzel, J., Poustka, A., Rosenthal, A., Platzer, M., Stratling, W. H., Kioschis, P., (2000) Comparative sequence analysis of the MECP2ßlocus in man and mouse reveals novel transcribed regions. Mamm Genome, 11:182-190
     link to pubmed
     
     
270. Mollenhauer, J., Herbertz, S., Holmskov, U., Tolnay, M., Krebs, I., Merlo, A., Schroder, H. D., Maier, D., Breitling, F., Wiemann, S., Grone, H. J., Poustka, A., (2000) DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer. Cancer Res, 60:1704-1710
     link to pubmed
     
     
271. Mallon, A. M., Platzer, M., Bate, R., Gloeckner, G., Botcherby, M. R., Nordsiek, G., Strivens, M. A., Kioschis, P., Dangel, A., Cunningham, D., Straw, R. N., Weston, P., Gilbert, M., Fernando, S., Goodall, K., Hunter, G., Greystrong, J. S., Clarke, D., Kimberley, C., Goerdes, M., Blechschmidt, K., Rump, A., Hinzmann, B., Mundy, C. R., Miller, W., Poustka, A., Herman, G. E., Rhodes, M., Denny, P., Rosenthal, A., Brown, S. D., (2000) Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. Genome Res, 10:758-75
     link to pubmed
     
     
272. Los, M., Neubuser, D., Coy, J. F., Mozoluk, M., Poustka, A., Schulze-Osthoff, K., (2000) Functional characterization of DNase X, a novel endonuclease expressed in muscle cells. Biochemistry, 39:7365-73
     link to pubmed
     
     
273. Koch, J., Breitling, F., Dubel, S., (2000) Rapid titration of multiple samples of filamentous bacteriophage (M13) on nitrocellulose filters. Biotechniques, 29:1196-8, 2002
     link to pubmed
     
     
274. Hoff, C., Seranski, P., Mollenhauer, J., Korn, B., Detzel, T., Reinhardt, R., Ramser, J., Poustka, A., (2000) Physical and transcriptional mapping of the 17p13.3 region that is frequently deleted in human cancer. Genomics, 70:26-33
     link to pubmed
     
     
275. Heiss, N. S., Bachner, D., Salowsky, R., Kolb, A., Kioschis, P., Poustka, A., (2000) Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1. Genomics, 67:153-63
     link to pubmed
     
     
276. Finzer, P., Soto, U., Delius, H., Patzelt, A., Coy, J. F., Poustka, A., zur Hausen, H., Rosl, F., (2000) Differential transcriptional regulation of the monocyte-chemoattractant protein-1 (MCP-1) gene in tumorigenic and non-tumorigenic HPV 18 positive cells: the role of the chromatin structure and AP-1 composition. Oncogene, 19:3235-44
     link to pubmed
     
     
277. Briault, S., Villard, L., Rogner, U., Coy, J., Odent, S., Lucas, J., Passage, E., Zhu, D., Shrimpton, A., Pembrey, M., Till, M., Guichet, A., Dessay, S., Fontes, M., Poustka, A., Moraine, C., (2000) Mapping of X chromosome inversion breakpoints [inv(X)(q11q28)] associated with FG syndrome: a second FG locus [FGS2]?. Am J Med Genet, 95:178-81
     link to pubmed
     
     
278. Breitling, F., Schmiedl, A., Winter, C. H., Queitsch, I., Dübel, S., (2000) Effect of engineered cysteines on yield, solubility and activity in various recombinant antibody formats expressed in E. coli.. Protein Eng, 13:725-734
     link to pubmed
     
     
279. Beissbarth, T., Fellenberg, K., Brors, B., Arribas-Prat, R., Boer, J., Hauser, N. C., Scheideler, M., Hoheisel, J. D., Schutz, G., Poustka, A., Vingron, M., (2000) Processing and quality control of DNA array hybridization data. Bioinformatics, 16:1014-22
     link to pubmed
     
     
280. Aradhya, S., Nelson, D. L., Heiss, N. S., Poustka, A., Woffendin, H., Kenwrick, S., Esposito, T., Ciccodicola, A., Bardaro, T., D'Urso, M., Smahi, A., Munnich, A., Herman, G. E., Lewis, R. A., (2000) Human homologue of the murine bare patches/striated gene is not mutated in incontinentia pigmenti type 2. Am J Med Genet, 91:241-4
     link to pubmed
     
     
281. Aradhya, S., Ahobila, P., Lewis, R. A., Nelson, D. L., Esposito, T., Ciccodicola, A., Bardaro, T., D'Urso, M., Woffendin, H., Kenwrick, S., Smahi, A., Heuertz, S., Munnich, A., Heiss, N. S., Poustka, A., Chishti, A. H., (2000) Filamin (FLN1), plexin (SEX), major palmitoylated protein p55 (MPP1), and von-Hippel Lindau binding protein (VBP1) are not involved in incontinentia pigmenti type 2. Am J Med Genet, 94:79-84
     link to pubmed
     
     
282. Wolf, S., Sharpe, L. T., Schmidt, H. J., Knau, H., Weitz, S., Kioschis, P., Poustka, A., Zrenner, E., Lichter, P., Wissinger, B., (1999) Direct visual resolution of gene copy number in the human photopigment gene array. Invest Ophthalmol Vis Sci, 40:1585-9
     link to pubmed
     
     
283. Vulliamy, T. J., Knight, S. W., Heiss, N. S., Smith, O. P., Poustka, A., Dokal, I., Mason, P. J., (1999) Dyskeratosis congenita caused by a 3' deletion: germline and somatic mosaicism in a female carrier. Blood, 94:1254-60
     link to pubmed
     
     
284. von Deimling, A., Larson, J., Wellenreuther, R., Stangl, A. P., van Velthoven, V., Warnick, R., Tew, J., Balko, G., Menon, A.G., (1999) Clonal origin of recurrent meningiomas. Brain Pathol, 9:645-650
     link to pubmed
     
     
285. Vente, A., Korn, B., Zehetner, G., Poustka, A., Lehrach, H., (1999) Distribution and early development of microarray technology in Europe. Nat Genet, 22:22
     link to pubmed
     
     
286. Seranski, P., Heiss, N. S., Dhorne-Pollet, S., Radelof, U., Korn, B., Hennig, S., Backes, E., Schmidt, S., Wiemann, S., Schwarz, C. E., Lehrach, H., Poustka, A., (1999) Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes. Genomics, 56:1-11
     link to pubmed
     
     
287. Sedlacek, Z., Shimeld, S. M., Munstermann, E., Poustka, A., (1999) The amphioxus rab GDP-dissociation inhibitor (GDI) gene is neural-specific: implications for the evolution of chordate rab GDI genes. Mol Biol Evol, 16:1231-7
     link to pubmed
     
     
288. Sedlacek, Z., Munstermann, E., Dhorne-Pollet, S., Otto, C., Bock, D., Schutz, G., Poustka, A., (1999) Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis. Genomics, 61:125-32
     link to pubmed
     
     
289. Scheurlen, W. G., Schwabe, G. C., Seranski, P., Joos, S., Harbott, J., Metzke, S., Dohner, H., Poustka, A., Wilgenbus, K., Haas, O. A., (1999) Mapping of the breakpoints on the short arm of chromosome 17 in neoplasms with an i(17q). Genes Chromosomes Cancer, 25:230-40
     link to pubmed
     
     
290. Peters, N., Waha, A., Wellenreuther, R., Friedrich, R.E., Mautner, V.F., Hoffmeyer, S., Lenartz, D., Schramm, J., Wiestler, O.D., von Deimling, A., (1999) Quantitative analysis of NF1 and OMGP gene transcripts in sporadic gkiomas, sporadic meningiomas and neurofibromatiois type 1 - associated plexiform neurofibromas. Acta Neuropathol, 97:547-551
     link to pubmed
     
     
291. Monaghan, A. P., Kioschis, P., Wu, W., Zuniga, A., Bock, D., Poustka, A., Delius, H., Niehrs, C., (1999) Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev, 87:45-56
     link to pubmed
     
     
292. Mollenhauer, J., Holmskov, U., Wiemann, S., Krebs, I., Herbertz, S., Madsen, J., Kioschis, P., Coy, J. F., Poustka, A., (1999) The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability. Oncogene, 18:6233-40
     link to pubmed
     
     
293. Maestrini, E., Lai, C., Marlow, A., Matthews, N., Wallace, S., Bailey, A., Cook, E.H., Weeks, D.E., Monaco, A.P., The international Molecular Genetic Study of Autism (IMGSA) Consortium (Klauck, S.M.; Beyer, K.S.; Spieler, A.; Poustka, A.Ö Poustka, F.; Rühl, D.; Schmötzer, G.; Bölte, S.;), (1999) Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families.. Am J Hum Genet, 88:492-496
     link to pubmed
     
     
294. Knight, S. W., Heiss, N. S., Vulliamy, T. J., Greschner, S., Stavrides, G., Pai, G. S., Lestringant, G., Varma, N., Mason, P. J., Dokal, I., Poustka, A., (1999) X-linked dyskeratosis congenita is predominantly caused by missense mutations in the DKC1 gene. Am J Hum Genet, 65:50-8
     link to pubmed
     
     
295. Knight, S. W., Heiss, N. S., Vulliamy, T. J., Aalfs, C. M., McMahon, C., Richmond, P., Jones, A., Hennekam, R. C., Poustka, A., Mason, P. J., Dokal, I., (1999) Unexplained aplastic anaemia, immunodeficiency, and cerebellar hypoplasia (Hoyeraal-Hreidarsson syndrome) due to mutations in the dyskeratosis congenita gene, DKC1. Br J Haematol, 107:335-9
     link to pubmed
     
     
296. Holmskov, U., Mollenhauer, J., Madsen, J., Vitved, L., Gronlund, J., Tornoe, I., Kliem, A., Reid, K. B., Poustka, A., Skjodt, K., (1999) Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Proc Natl Acad Sci U S A, 96:10794-9
     link to pubmed
     
     
297. Heiss, N. S., Poustka, A., Knight, S. W., Aradhya, S., Nelson, D. L., Lewis, R. A., Esposito, T., Ciccodicola, A., D'Urso, M., Smahi, A., Heuertz, S., Munnich, A., Vabres, P., Woffendin, H., Kenwrick, S., (1999) Mutation analysis of the DKC1 gene in incontinentia pigmenti. J Med Genet, 36:860-2
     link to pubmed
     
     
298. Heiss, N. S., Girod, A., Salowsky, R., Wiemann, S., Pepperkok, R., Poustka, A., (1999) Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita. Hum Mol Genet, 8:2515-24
     link to pubmed
     
     
299. Eickhoff, B., Korn, B., Schick, M., Poustka, A., van der Bosch, J., (1999) Normalization of array hybridization experiments in differential gene expression analysis. Nucleic Acids Res, 27:e33
     link to pubmed
     
     
300. Coy, J. F., Sedlacek, Z., Bachner, D., Delius, H., Poustka, A., (1999) A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3"-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression. Hum Mol Genet, 8:1253-62
     link to pubmed
     
     
301. The International Molecular Genetic Study of Autism Consortium,, (1998) A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Hum Mol Genet, 7:571-578
     link to pubmed
     
     
302. Sedlacek, Z., Munstermann, E., Mincheva, A., Lichter, P., Poustka, A., (1998) The human rab GDI beta gene with long retroposon-rich introns maps to 10p15 and its pseudogene to 7p11-p13. Mamm Genome, 9:78-80
     link to pubmed
     
     
303. Sedlacek, Z., Kodet, R., Seemanova, E., Vodvarka, P., Wilgenbus, P., Mares, J., Poustka, A., Goetz, P., (1998) Two Li-Fraumeni syndrome families with novel germline p53 mutations: loss of the wild-type p53 allele in only 50% of tumours. Br J Cancer, 77:1034-9
     link to pubmed
     
     
304. Sedlacek, Z., Kodet, R., Poustka, A., Goetz, P., (1998) A database of germline p53 mutations in cancer-prone families. Nucleic Acids Res, 26:214-5
     link to pubmed
     
     
305. Scheurlen, W., Schwabe, G. C., Joos, S., Mollenhauer, J., Sorensen, N., Kuhl, J., (1998) Molecular analysis of childhood primitive neuroectodermal tumours defines markers associated with poor outcome. J Clin Oncol, 16:2478-2485
     link to pubmed
     
     
306. Rondot, S., Anthony, K. G., Dubel, S., Ida, N., Wiemann, S., Beyreuther, K., Frost, L. S., Little, M., Breitling, F., (1998) Epitopes fused to F-pilin are incorporated into functional recombinant pili. J Mol Biol, 279:589-603
     link to pubmed
     
     
307. Radelof, U., Hennig, S., Seranski, P., Steinfath, M., Ramser, J., Reinhardt, R., Poustka, A., Francis, F., Lehrach, H., (1998) Preselection of shotgun clones by oligonucleotide fingerprinting: an efficient and high throughput strategy to reduce redundancy in large-scale sequencing projects. Nucleic Acids Res, 26:5358-64
     link to pubmed
     
     
308. Nikolic, Z., Laube, B., Weber, R. G., Lichter, P., Kioschis, P., Poustka, A., Mulhardt, C., Becker, C. M., (1998) The human glycine receptor subunit a3: Structure of the GLRA3 gene, localization to the distal chromosome 4q, and functional characterization of alternative transcripts. J Biol Chem, 273:19708-19714
     link to pubmed
     
     
309. Milani, N., Mülhardt, C., Weber, R.G., Lichter, P., Kioschis, P., Poustka, A., Becker, C. M., (1998) The human glycine receptor b subunit gene (GLRB): structure, refined chromosomal localization and population polymorphism.. Genomics, 50:341-345
     link to pubmed
     
     
310. Knight, S. W., Vulliamy, T. J., Heiss, N. S., Matthijs, G., Devriendt, K., Connor, J. M., D'Urso, M., Poustka, A., Mason, P. J., Dokal, I., (1998) 1.4 Mb candidate gene region for X linked dyskeratosis congenita defined by combined haplotype and X chromosome inactivation analysis. J Med Genet, 35:993-6
     link to pubmed
     
     
311. Klauck, S. M., Poustka, A., Poustka, F., (1998) Genetik des Autismus. Med Genet, 19:409-411
     
     
     
312. Kischkel, F. C., Kioschis, P., Weitz, S., Poustka, A., Lichter, P., Krammer, P. H., (1998) Assignment of CASP8 to human chromosome band 2q33-->q34 and Casp8 to the murine syntenic region on chromosome 1B-proximal C by in situ hybridization. Cytogenet Cell Genet, 82:95-6
     link to pubmed
     
     
313. Kioschis, P., Wiemann, S., Heiss, N. S., Francis, F., Gotz, C., Poustka, A., Taudien, S., Platzer, M., Wiehe, T., Beckmann, G., Weber, J., Nordsiek, G., Rosenthal, A., (1998) Genomic organization of a 225-kb region in Xq28 containing the gene for X-linked myotubular myopathy (MTM1) and a related gene (MTMR1). Genomics, 54:256-66
     link to pubmed
     
     
314. Heiss, N. S., Knight, S. W., Vulliamy, T. J., Klauck, S. M., Wiemann, S., Mason, P. J., Poustka, A., Dokal, I., (1998) X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions. Nat Genet, 19:32-8
     link to pubmed
     
     
315. Haas, S., Vingron, M., Poustka, A., Wiemann, S., (1998) Primer design for large scale sequencing. Nucleic Acids Res, 26:3006-12
     link to pubmed
     
     
316. Dahamne, N. , Ghezala, G.A.,, Gosset, P., Chamoun, Z., Dufresne-Yacharia, M.C., Lopes, C., Rabatel, N., Gassanova-Maugenre, S., Chettouh, Z. , Abramowski, V., Fayet, E., Yaspo, M.L., Korn, B., Blouin, J.L., Lehrach, H., Poustka, A., Antonarakis, S.E., Sinet, P.M., Créau, N., Delabar, J.M., (1998) Transcriptional map of the 2.5 Mb CBR-ERG region of chromosome 21 involved in Down syndrome. Genomics, 48:12-23
     link to pubmed
     
     
317. Wilke, K., Wiemann, S., Gaul, R., Gong, W., Poustka, A., (1997) Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a-specific 3' untranslated region. Gene, 198:269-74
     link to pubmed
     
     
318. Wilke, K., Gaul, R., Klauck, S. M., Poustka, A., (1997) A gene in human chromosome band Xq28 (GABRE) defines a putative new subunit class of the GABAA neurotransmitter receptor. Genomics, 45:1-10
     link to pubmed
     
     
319. Wilgenbus, K., Seranski, P., Brown, A., Leuchs, B., Mincheva, A., Lichter, P., Poustka, A., (1997) Molecular characterisation of a genetically unstable region containing the SMSßcritical area and a breakpoint cluster for human PNET's. Genomics, 42:1-10
     link to pubmed
     
     
320. Seither, P., Coy, J., Poustka, A., Grummt, I., (1997) Molecular cloning and characterisation of the cDNA encoding the largest subunit of mouse RNA polymerase I.. Mol Gen Genet, 255:180-186
     link to pubmed
     
     
321. Scheurlen, W. G., Seranski, P., Mincheva, A., Kuhl, J., Sorensen, N., Krauss, J., Lichter, P., Poustka, A., Wilgenbus, K. K., (1997) High-resolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11.2. Genes Chromosomes Cancer, 18:50-8
     link to pubmed
     
     
322. Mollenhauer, J., Wiemann, S., Scheurlen, W., Korn, B., Hayashi, Y., Wilgenbus, K. K., von Deimling, A., Poustka, A., (1997) DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet, 17:32-9
     link to pubmed
     
     
323. Lesch, K. P., Meyer, J., Glatz, K., Flugge, G., Hinney, A., Hebebrand, J., Klauck, S. M., Poustka, A., Poustka, F., Bengel, D., Mossner, R., Riederer, P., Heils, A., (1997) The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: alternative biallelic variation in rhesus monkeys. Rapid communication. J Neural Transm, 104:1259-66
     link to pubmed
     
     
324. Laporte, J., Kioschis, P., Hu, L. J., Kretz, C., Carlsson, B., Poustka, A., Mandel, J. L., Dahl, N., (1997) Cloning and characterization of an alternatively spliced gene in proximal Xq28 deleted in two patients with intersexual genitalia and myotubular myopathy. Genomics, 41:458-62
     link to pubmed
     
     
325. Klauck, S. M., Poustka, F., Benner, A., Lesch, K. P., Poustka, A., (1997) Serotonin transporter (5-HTT) gene variants associated with autism?. Hum Mol Genet, 6:2233-8
     link to pubmed
     
     
326. Klauck, S. M., Munstermann, E., Bieber-Martig, B., Ruhl, D., Lisch, S., Schmotzer, G., Poustka, A., Poustka, F., (1997) Molecular genetic analysis of the FMR-1 gene in a large collection of autistic patients. Hum Genet, 100:224-9
     link to pubmed
     
     
327. Heiss, N. S., Poustka, A., (1997) Genomic structure of a novel chloride channel gene, CLIC2, in Xq28. Genomics, 45:224-8
     link to pubmed
     
     
328. Heiss, N. S., Gloeckner, G., Bachner, D., Kioschis, P., Klauck, S. M., Hinzmann, B., Rosenthal, A., Herman, G. E., Poustka, A., (1997) Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript. Genomics, 43:329-38
     link to pubmed
     
     
329. Briault, S., Hill, R., Shrimpton, A., Zhu, D., Till, M., Ronce, N., Margaritte-Jeannin, P., Baraitser, M., Middleton-Price, H., Malcolm, S., Thompson, E., Hoo, J., Wilson, G., Romano, C., Guichet, A., Pembrey, M., Fontes, M., Poustka, A., Moraine, C., (1997) A gene for FG syndrome maps in the Xq12-q21.31 region. Am J Med Genet, 73:87-90
     link to pubmed
     
     
330. Albig, W., Kioschis, P., Poustka, A., Meergans, K., Doenecke, D., (1997) Human histone gene organisation: non-regular arrangement within a large cluster. Genomics, 40:314-322
     link to pubmed