2011
Meitinger F, Boehm ME, Hofmann A, Hub B, Zentgraf H, Lehmann WD, Pereira G. Genes Dev 2011, 25, 875-888. Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis.
Bachmann J, Raue A, Schilling M, Böhm ME, Kreutz C, Kaschek D, Busch H, Gretz N, Lehmann WD, Timmer J, Klingmüller U. Mol Syst Biol 2011, 7, 516. Division of Labor by Dual Feedback Regulators Controls JAK2/STAT5 Signaling over Broad Ligand Range
Hahn B, Boehm ME, Zinn N, Möller P, Klingmüller U, Lehmann WD. Proteomics 2011, 11, 490-494. One-Source Peptide/Phosphopeptide Standards for Accurate Phosphorylation Degree Determination.
Seidler J, Zinn N, Haaf E, Boehm ME, Winter D, Schlosser A, Lehmann WD. Amino Acids, 2011, 41, 311-320. Metal Ion-Mobilizing Additives for Comprehensive Detection of Femtomole Amounts of Phosphopeptides by Reversed Phase LC-MS.
Kaltner H, López-Merino Lara; Lohr M, Manning J, Lensch M, Seidler J, Lehmann W, Andre S, Solís D, Gabius HJ. Anatomical Record, 2011, 294, 427-444. Towards Comprehensive Analysis of the Galectin Network in Chicken: Unique Diversity of Galectin-3 and Comparison of its Localization Profile in Organs of Adult Animals to the Other Four Members of this Lectin Family.
Raia V, Schilling M, Böhm ME, Hahn B, Kowarsch A, Raue A, Sticht C, Bohl S, Saile M, Möller P, Gretz N Joos S, Timmer J, Theis F, Lehmann WD, Lichter P, Klingmüller U. Cancer Res 2011, 71, 693-704. Dynamic Mathematical Modeling of IL13-induced Signaling in Hodgkin and Primary Mediastinal B-cell Lymphoma Allows Prediction of Therapeutic Targets
2010
Derrer B, Windeisen V, Guedez Rodriguez G, Seidler J, Gengenbacher M, Lehmann WD, Rippe K, Sinning I, Tews I, Kappes B. FEBS Letters 2010, 584, 4169-4174.Defining the structural requirements of ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase
Lehmann WD. Protein Phosphorylation Analysis by Electrospray Mass Spectrometry – A Guide to Concepts and Practice
Royal Society of Chemistry, London, 2010, ISBN: 978-0-85404-185-5.
Winter D, Seidler J, Hahn B, Lehmann WD. J Am Soc Mass Spectrom 2010, 21, 1814-1820. Structural and mechanistic information on c(1) ion formation in collision-induced fragmentation of peptides.
Erlbruch A, Hung CW, Seidler J, Borrmann K, Gesellchen F, König N, Kübler D, Herberg FW, Lehmann WD, Bossemeyer D. Proteomics 2010, 10, 2890-900.
Uncoupling of bait-protein expression from the prey protein environment adds versatility for cell and tissue interaction proteomics and reveals a complex of CARP-1 and the PKA Cbeta1 subunit.
Winter D, Seidler J, Kugelstadt D, Derrer B, Kappes B, Lehmann WD. Proteomics 2010, 10, 1510-1514.
Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins
Zinn N, Winter D, Lehmann WD. Anal. Chem. 2010, 82, 2334-2340.
Recombinant isotope labeled and selenium quantified proteins for absolute protein quantification
Seidler J, Zinn N, Boehm ME, Lehmann WD. Proteomics 2010, 10, 634-649.
De novo sequencing of peptides by MS/MS
2009
Winter D, Seidler J, Ziv-Lehrman S, Shiloh Y, Lehmann WD. Anticancer Res. 2009, 29, 4949-4958.
Simultaneous identification and quantification of proteins by differential (16)O/(18)O labeling and UPLC-MS/MS applied to mouse cerebellar phosphoproteome following irradiation
Schilling M, Maiwald T, Hengl S, Winter D, Kreutz C, Kolch W, Lehmann WD, Timmer J, Klingmüller U. Mol. Syst. Biol. 2009, 5, 334.
Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions
Brenner, D., Brechmann, M., Röhling, S., Tapernoux, M., Mock, T., Winter, D., Lehmann, WD., Kiefer, F., Thome, M., Krammer, PH., Arnold, R.
Proc Natl Acad Sci U S A 2009, 106, 4508-4513.
Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells
Zinn N, Hahn B, Pipkorn R, Schwarzer D, Lehmann WD. J Proteome Res 2009, 8, 4870-4875.
Phosphorus based Absolutely Quantified Standard (PASTA) Peptides for Quantitative Proteomics
Seidler J, Adal M, Kübler D, Bossemeyer D, Lehmann WD. Anal Bioanal Chem 2009, 395, 1713-1720.
Analysis of autophosphorylation sites in the recombinant catalytic subunit alpha of cAMP-dependent kinase by nano-UPLC-ESI-MS/MS
Winter D, Kugelstadt D, Seidler J, Kappes B, Lehmann WD. Anal Biochem 2009, 393, 41-47.
Protein phosphorylation influences proteolytic cleavage and kinase substrate properties exemplified by analysis of in vitro phosphorylated Plasmodium falciparum glideosome-associated protein 45 by nano-ultra performance liquid chromatography-tandem mass spectrometry
Braun A, Treede I, Gotthardt D, Tietje A, Zahn A, Ruhwald R, Schoenfeld U, Welsch T, Kienle P, Erben G, Lehmann WD, Fuellekrug J, Stremmel W, Ehehalt R. Inflamm Bowel Dis 2009, 15, 1705-1720.
Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: A clue to pathogenesis
Edelson-Averbukh M, Shevchenko A, Pipkorn R, Lehmann WD. Anal Chem 2009, 81, 4369-4381.
Gas-phase intramolecular phosphate shift in phosphotyrosine-containing peptide monoanions
Krüger R, Zinn N, Lehmann WD. In: Phospho-Proteomics: Methods and Protocols, Series: Methods in Molecular Biology, Humana Press, de Graauw, M (Eds.), 2009, 527, 201-218.
Quantification of Protein Phosphorylation by μLC-ICP-MS
Winter D, Lehmann WD. Anal Bioanal Chem 2009, 393, 1587-1591.
Individual b2 Ion Fragmentation Profiles Combined with AspN Digestion Improve N-terminal Peptide Sequencing.
Winter D, Pipkorn R, Lehmann WD. J Separation Sci 2009, 32, 1111-1119.
Separation of Peptide Isomers and Conformers by Ultra Performance Liquid Chromatography
Winter D, Lehmann WD. Proteomics 2009, 9,2076-2084.
Sequencing of the Thirteen Structurally Isomeric Quartets of N-terminal Dipeptide Motifs in Peptides by Collision-induced Dissociation.
Winter D, Seidler J, Ziv Y, Shiloh Y, Lehmann WD. J Proteome Res 2009, 8, 418-424.
Citrate boosts the performance of phosphopeptide analysis by UPLC ESI-MS/MS.
2008
Korf U, Derdak S, Tresch A, Henjes F, Schumacher S, Schmidt C, Hahn B, Lehmann WD, Poustka A, Tim Beissbarth T, Klingmüller U. Proteomics 2008, 8, 4603-4612.
Quantitative protein microarrays for time-resolved measurements of protein phosphorylation,
Jaskolla TW, Lehmann WD, Karas M. Proc Natl Acad Sci USA 2008, 105, 12200-12205.
4-Chloro-α-cyanocinnamic acid is an advanced, rationally designed MALDI matrix.
Kubler D, Hung CW, Dam TK, Kopitz J, Andre S, Kaltner H, Lohr M, Manning JC, He L, Wang H, Middelberg A, Brewer CF, Reed J, Lehmann WD, Gabius HJ. Biochim Biophys Acta 2008, 1780, 716-722.
Phosphorylated human galectin-3: facile large-scale preparation of active lectin and detection iof structural changes by CD spectroscopy.
2007 and previous
Hung CW, Schlosser A, Wei J, Lehmann WD. Anal Bioanal Chem 2007, 389, 1003-1016.
Collision-induced reporter fragmentations for identification of covalently modified peptides.
Lehmann WD, Krüger R, Salek M, Hung CW, Wolschin F, Weckwerth W. J Proteome Res 2007, 6, 2866-2873.
Neutral loss-based phosphopeptide recognition – a collection of caveats.
Kugelstadt D, Winter D, Plückhahn K, Lehmann WD, Kappes B. Mol Biochem Parasitol 2007, 151, 111-117.
Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1.
Krüger R, Wolschin F, Weckwerth W, Bettmer J, Lehmann WD. Biochem Biophys Res Commun 2007, 355, 89-96.
Plant Protein Phosphorylation monitored by capillary liquid chromatography-element mass spectrometry.
Edelson-Averbukh M, Pipkorn R, Lehmann WD. Anal Chem 2007, 79, 3476-3486.
Analysis of protein phosphorylation in the regions of consecutive serine/threonine residues by negative ion electrospray collision-induced dissociation. Approach to pinpointing of phosphorylation sites.
Krüger R, Kübler D, Pallissé R, Burkovski A, Lehmann WD. Anal Chem 2006, 78, 1987-1994.
Protein and Proteome Phosphorylation Stoichiometry Analysis by Element Mass Spectrometry.
Edelson-Averbukh M, Pipkorn R, Lehmann WD. Anal Chem 2006, 78, 1249-1256.
Phosphate Group-Driven Fragmentation of Multiply Charged Phosphopeptide Anions – Improved Recognition of Peptides Phosphorylated at Serine, Threonine or Tyrosine by Negative Ion Electrospray Tandem Mass Spectrometry.
Salek M, Di Bartolo V, Cittaro D, Borsotti D, Wei J, Acuto O, Rappsilber J, Lehmann WD. Proteomics 2005, 5, 667-674.
Sequence Tag Scanning: A New Explorative Strategy for Recognition of Unexpected Protein Alterations by nanoESI-MS/MS.
Krüger R, Hung CW, Edelson-Averbukh M, Lehmann WD. Rapid Commun Mass Spectrom 2005, 19, 1709-1716.
Iodoacetamide-alkylated methionine may mimic neutral loss of phosphoric acid from phosphopeptides as exemplified by nanoESI QTOF parent ion scanning..
Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Teunisse AFAS, Lehmann WD, Jochemsen AG, Shiloh Y. Proc Natl Acad Sci USA 2005, 102, 5056-5061.
Multiple phosphorylations of Hdmx mediate its Hdm2- and ATM-dependent degradation in response to DNA damage.
Wind M, Lehmann WD. J Anal At Spectrom 2004, 19, 20 - 25.
Element and molecular mass spectrometry – an analytical dream team in the life sciences.
Wind M, Feldmann I, Jakubowski N, Lehmann WD. Electrophoresis 2003, 24, 1276-1280.
Spotting and quantification of phosphoproteins purified by gel electrophoresis by laser ablation element mass spectrometry with phosphorus-31 detection.
Wind M, Wegener A, Eisenmenger A, Kellner R, Lehmann WD. Angew Chem Int Ed Engl 2003, 42 3425-3427.
Sulfur as the key element for quantitative protein analysis by capillary liquid chromatography coupled to element mass spectrometry
Kelm O, Wind M, Lehmann WD, Nigg EA. J Biol Chem 2002, 277, 25247-56.
Cell-cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1.
Wind M, Edler M, Jakubowski N, Linscheid M, Wesch H, Lehmann WD. Anal Chem 2001, 73, 29-35. Analysis of protein phosphorylation by capillary liquid chromatography coupled to element mass spectrometry with 31P detection and to electrospray mass spectrometry.
Schlosser A, Pipkorn R, Bossemeyer D, Lehmann WD. Anal Chem 2001, 73, 170-176.
Analysis of protein phosphorylation by combination of elastase digest and neutral loss tandem mass spectrometry.
Wind M, Wesch H, Lehmann WD. Anal Chem 2001, 73, 3006-3010.
Protein phosphorylation degree – Determination by capillary liquid chromatography and inductively coupled plasma mass spectrometry.
Schlosser A, Lehmann WD. J Mass Spectrom 2000, 35, 1382-1390.
Five-membered ring formation in unimolecular reactions of peptides: a key structural element controlling low-energy collision-induced dissociation of peptides.
