del_knr4

23-Jul-2002 by nhauser
multiconditional experiment no. (if not recombined):
hybridisations (conditions & MCE(s) marked by brackets): {{18,19,20,21},{22,23,24,25}}
normalization method [parameters]: log. reg. 2
intensity threshold: 400000

			factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
			condition1	condition0(CONTROL)	condition1	functional category	description
			delta knr4	wt, strain AR27	delta knr4


*	YAL001C	TFC3______	-1.04	99141	95377	transcription	TFIIIC 138 kD subunit
	YBR166C	TYR1______	-1.19	376129	314794	tyrosine biosynthesis	prephenate dehydrogenase (NADP+
	YCR102W	__________	-1.35	167403	123714	unknown	unknown
	YDR037W	KRS1______	-1.24	2470167	1992865	protein synthesis	tRNA synthetase, lysyl
	YDR404C	RPB7______	-1.04	605771	584728	transcription	RNA polymerase II 19 kD subunit
	YER099C	PRS2______	-1.25	601923	481742	purine biosynthesis	ribose-phosphate pyrophosphokinase
	YGL097W	SRM1______	-1.19	701082	591493	nuclear targeting; mating	GDP/GTP exchange factor for Gsp1p/Gsp2p
	YGR204W	ADE3______	-1.33	520141	390676	purine biosynthesis	C1-5,6,7,8-tetrahydrofolate synthase
	YIL001W	__________	+1.05	197188	206874	unknown	unknown
	YJL098W	SAP185____	-1.16	227752	195876	cell cycle	Sit4p-associated protein
	YKL095W	YJU2______	-1.27	124741	98487	unknown	unknown
	YLR030W	__________	-1.11	130945	117601	unknown	unknown
	YLR402W	__________	-1.16	125157	108003	unknown	unknown
	YNL189W	SRP1______	-1.05	1314089	1248407	nuclear protein targeting	alpha-karyopherin
	YOL095C	HMI1______	-1.14	177381	156153	unknown	mitochondrial DNA helicase (putative)
	YOR305W	__________	-1.00	607611	605078	unknown	unknown
	YPL283C	YRF1-7____	-1.12	134932	120655	unknown	Y' helicase (subtelomerically-encoded)
	YBL095W	__________	+1.01	227409	230135	unknown	unknown
	YCL001W	RER1______	-1.04	105053	101154	secretion; protein targeting	ER protein retention (Golgi membrane protein)
	YDL097C	RPN6______	+1.07	1233382	1321411	protein degradation	26S proteasome regulatory subunit
	YDR220C	__________	+1.03	112050	115823	unknown	unknown
	YEL001C	__________	+1.18	1153008	1360455	unknown	unknown
	YFR020W	__________	-1.01	195000	193205	unknown	unknown
	YGR025W	__________	-1.18	115766	98158	unknown	unknown
	YHR038W	FIL1______	+1.04	221148	229978	protein syntehsis	robosomal protein, mitochondrial (putative)
	YIR008C	PRI1______	-1.07	296776	277678	DNA replication	DNA primase subunit
	YJR064W	CCT5______	-1.15	1381352	1205664	protein targeting	cytoplasmic chaperonin complex
	YKR061W	KTR2______	+1.98	199645	395757	protein glycosylation	putative mannosyltransferase; type 2 membrane protein
	YLR218C	__________	+1.09	151242	164768	unknown	unknown
	YML088W	__________	-1.08	374057	347859	unknown	unknown
	YNL001W	DOM34_____	-1.09	539929	497434	protein synthesis (putative)	unknown
	YNR040W	__________	-1.01	103884	102417	unknown	unknown; zinc regulated
	YOR119C	RIO1______	-1.43	346700	241665	unknown	unknown; similar to a C.elegans ZK632.3 protein
	YPL095C	__________	-1.02	221569	216723	unknown	unknown; similar to Ybr177p
	YPR186C	PZF1______	+1.02	353012	358668	transcription	TFIIIA
	YAL014C	__________	-1.19	381315	320803	unknown	unknown
	YBR178W	__________	-1.12	105493	93954	unknown	unknown
	YCRX08W	__________	-1.15	134880	116889
	YDR049W	__________	-1.11	194595	174586	unknown	unknown
	YDR416W	SYF1______	-1.12	196881	175177	cell cycle (putative)	unknown; synthetic lethal with cdc40
	YER111C	SWI4______	-1.04	254501	244272	cell cycle	transcription factor
	YGL109W	__________	+1.02	298577	304427	unknown	unknown
	YGR216C	GPI1______	+1.05	281093	296477	protein processing	N-acetylglucosaminylphosphatidylinositol synthesis
	YIL013C	PDR11_____	-1.15	140852	122862	transport	ATP-binding cassette (ABC) family
	YJL110C	GZF3______	-1.06	305179	287596	nitrogen catabolism	transcription factor
	YKL106W	AAT1______	-1.13	325575	287053	aspartate metabolism?	aspartate aminotransferase,
	YLR040C	__________	+1.16	1153960	1332996	unknown	unknown
	YLR412W	__________	+1.03	358209	368198	unknown	unknown
	YMR147W	__________	-1.17	159593	136824	unknown	unknown
	YNL201C	__________	-1.04	101178	96925	unknown	unknown
	YOL105C	WSC3______	-1.20	348077	290217	signaling	stress response
	YOR317W	FAA1______	+1.05	681196	713013	fatty acid metabolism	long chain fatty acyl:CoA synthetase
	YPR012W	__________	-1.18	888653	751444	unknown	unknown
	YBL105C	PKC1______	-1.25	179192	143201	cell wall biogenesis	protein kinase C
	YCL012W	__________	-1.06	170015	160055	unknown	unknown
	YDL109C	__________	-1.24	133917	107568	unknown	unknown
	YDR232W	HEM1______	-1.34	294183	218764	heme biosynthesis	5-aminolevulinate synthase
	YEL013W	VAC8______	-1.17	270425	231115	vacuolar protein targeting	vacuolar protein
	YFR031C	RPL2A_____	-1.01	105721	105079	protein synthesis	ribosomal protein L2A
	YGR035C	__________	-1.17	149017	127726	unknown	unknown
	YHR049W	__________	-1.33	1009103	757440	unknown	unknown
	YIR019C	MUC1______	-1.11	149453	134669	flocculation and invasive growth	unknown
	YJR076C	CDC11_____	+1.02	806498	826519	cytokinesis	septin
	YKR073C	__________	-1.22	137962	112623	unknown	unknown
	YLR228C	ECM22_____	-1.17	199588	170350	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
	YML099C	ARG81_____	-1.03	170550	165887	arginine metabolism	transcription factor
	YNL013C	__________	+1.07	498406	532432	unknown	unknown
	YNR052C	POP2______	-1.03	1073183	1046421	glucose derepression	component of CCR4 complex
	YOR131C	__________	+1.12	399987	447762	unknown	unknown; similar to E. coli protein yhfE gene of the dam
	YPL107W	__________	+1.11	302355	336062	unknown	unknown
	YPR198W	SGE1______	+1.37	401546	550006	crystal violet resistance	transporter, major facilitator superfamily
	YAL026C	DRS2______	-1.18	275695	232893	transport	Ca(2+) transporting ATPase
	YBR190W	__________	-1.35	199189	147636	unknown	unknown; similar to glycosyl hydrolases
	YCRX20C	__________	-1.32	125239	94562
	YDR061W	__________	+1.02	303296	310470	unknown	unknown; similar to E. coli photorepair protein
	YDR428C	__________	+1.01	226653	229408	unknown	unknown
	YER122C	GLO3______	-1.14	664751	582008	cell proliferation	unknown
	YGL121C	__________	+1.09	183175	198852	unknown	unknown
	YGR228W	__________	-2.34	754394	321949	unknown	unknown
	YIL024C	__________	-1.33	346079	260148	unknown	unknown
	YJL122W	__________	-1.29	867844	672180	unknown	unknown
	YKL118W	__________	-1.14	148558	130451	unknown	unknown
	YLR052W	__________	-1.07	337430	314991	unknown	unknown
	YLR424W	__________	+1.03	186801	192694	unknown	unknown; similar to retrovirus-related protease
	YMR158W	__________	+1.07	278984	297910	unknown	unknown; similar E. coli ribosomal protein S8
	YNL213C	__________	+1.15	239877	276019	unknown	unknown
	YOL117W	__________	-1.01	138100	136118	unknown	unknown
	YOR329C	SCD5______	-1.08	290883	268609	secretion	suppressor of clathrin deficiency
	YPR024W	YME1______	-1.20	279907	232413	mitochondrial protein processing	AAA family protease
	YBR004C	__________	+1.14	226656	257524	unknown	expressed during sporulation
	YCL025C	AGP1______	+1.04	177314	183837	transport	amino acid permease
	YDL121C	__________	-1.03	716406	696697	unknown	unknown
	YEL024W	RIP1______	+1.18	714971	846544	respiration	ubiquinol cyt.-c reductase iron-sulfur protein
	YFR041C	__________	+1.15	410796	470608	unknown	unknown; similar to dnaJ proteins Sis1p, Mdj1p, and Scj1p
	YGR042W	__________	+1.29	293043	377563	unknown	unknown
	YHR059W	__________	+1.07	278446	298817	unknown	unknown
	YIR029W	DAL2______	-1.03	214099	208534	allantoin utilization	allantoicase
	YJR089W	BIR1______	-1.13	173823	153825	unknown	unknown
	YKR085C	MRPL20____	-1.02	393008	384672	protein synthesis	ribosomal protein, mitochondrial L20
	YLR240W	VPS34_____	-1.19	125148	105523	vacuolar protein targeting	phosphatidylinositol 3-kinase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YML109W	ZDS2______	-1.05	231520	219655	cell cycle	Zds1 homolog
YNL025C	SSN8______	-1.08	147696	136822	transcription	RNA polymerase II mediator subunit
YNR064C	__________	+1.11	187943	208249	unknown	unknown; similar to Rhodobacter capsulatus bchO
YPL119C	DBP1______	-1.12	161252	144449	mRNA processing	RNA helicase
YAL035W	FUN12_____	-1.39	774776	555830	unknown	unknown; similar to Bacillus subtilis IF2
YBR202W	CDC47_____	-1.34	350562	261549	DNA replication	MCM initiator complex
YDR073W	SNF11_____	+1.13	316073	356064	transcription	component of SWI/SNF global activator complex
YDR440W	DOT1______	-1.24	206223	165910	meiosis, checkpoint; transcriptional silencing	unknown
YER134C	__________	-1.19	91607	77062	unknown	unknown
YGL133W	ITC1______	+1.11	161373	179912	chromatin structure	chromatin remodeling complex subunit
YGR240C	PFK1______	-1.14	189876	166297	glycolysis	phosphofructokinase
YIL036W	CST6______	+1.06	307065	324405	chromosome stability	unknown; similar to Mei4p and to cAMP response element
YJL134W	LCB3______	-1.02	444193	436580	sphingolipid metabolism	sphingoid base-phosphate phosphatase
YKL130C	SHE2______	-1.12	250193	223120	cell polarity	asymmetric HO expression
YLR064W	__________	-1.03	529063	514919	unknown	unknown
YLR434C	__________	-1.35	190177	140724	unknown	unknown
YNL225C	CNM67_____	+1.05	147006	154919	cytoskeleton	spindle pole body component
YOL129W	__________	+1.26	586629	741915	unknown	unknown
YOR341W	RPA190____	-1.52	833115	548143	transcription	RNA polymerase I 190 kD subunit
YPR036W	VMA13_____	-1.06	1355383	1276611	vacuolar acidification	vacuolar H+-ATPase V1 domain 54 KD subunit
YBR014C	__________	+1.18	343765	404084	unknown	unknown; similar to glutaredoxin
YCL037C	SRO9______	-1.11	122730	110650	cytoskeleton	actin filament organization
YDL132W	CDC53_____	-1.02	274880	268705	cell cycle	G1 cyclin degradation
YDR256C	CTA1______	-1.12	159775	142798	oxidative stress response	catalase A
YEL036C	ANP1______	-1.06	1269342	1195911	protein glycosylation	mannosyltransferase complex subunit
YFR053C	HXK1______	-1.03	816900	793575	glycolysis	hexokinase I
YGR054W	__________	-1.34	277098	207017	unknown	unknown; similar to C. elegans C14B9.6 protein
YHR070W	__________	-1.44	262270	181939	unknown	unknown
YIR041W	__________	-1.01	268652	266264	unknown	unknown; similar to Pau3p, Yil176p, Yil011p and other
YJR100C	__________	-1.03	309561	301251	unknown	unknown
YKR097W	PCK1______	-1.16	157208	135674	TCA cycle	phosphoenolpyruvate carboxykinase
YLR252W	__________	+1.08	134954	145500	unknown	unknown
YML120C	NDI1______	+1.04	211826	219892	oxidative phosphorylation	NADH-ubiquinone-6 oxidoreductase
YNR076W	PAU6______	-1.03	377732	365491	unknown	seripauperin family
YOR153W	PDR5______	+1.22	1750802	2128346	drug resistance	transporter
YPL131W	RPL5______	+1.12	15729333	17613498	protein synthesis	ribosomal protein L5
YAL046C	__________	+1.22	308829	375856	unknown	unknown
YBR214W	SDS24_____	-1.03	111287	107967	unknown	unknown; nuclear protein; similar to S. pombe sds23
YDR085C	AFR1______	+1.37	172743	237044	mating	cytoskeletal protein, similar to arrestins
YDR452W	PHM5______	+1.04	439420	458888	phosphate metabolism (putative)	vacuolar polyphosphatase
YER144C	UBP5______	+1.04	146264	152160	unknown	ubiquitin pathway
YGL145W	TIP20_____	+1.03	329934	339613	secretion	unknown; interacts with Sec20p
YGR252W	GCN5______	-1.11	227773	205470	chromatin structure	histone acetyltransferase
YIL048W	NEO1______	-1.15	228640	198987	neomycin resistance	ATPase
YJL146W	IDS2______	-1.02	285941	281009	signaling, meiosis pathway	Putative activator of Ime2p
YKL142W	MRP8______	+1.37	572017	786081	protein synthesis	ribosomal protein, mitochondrial small subunit
YLR076C	__________	+1.06	15572295	16479846	unknown	unknown
YLR446W	__________	-1.01	345398	340387	unknown	unknown; similar to human hexokinase I
YMR179W	SPT21_____	+1.06	223198	235848	transcription	transcriptional regulator
YNL237W	YTP1______	+1.04	145658	151431	unknown	unknown; similar to mitochondrial electron transport proteins
YOL141W	PPM2______	+1.07	108995	116148	protein modification	carboxymethyltransferase
YOR351C	MEK1______	+1.02	108543	110498	meiosis	protein kinase
YPR048W	TAH18_____	-1.06	204292	193500	unknown	unknown; similar to NAPDH-cytochrome P450 reductase
YBR026C	(MRF1)____	+1.17	344562	402425	mitochondrial respiration	ARS-binding protein
YCL049C	__________	+1.35	234757	317412	unknown	unknown
YDL143W	CCT4______	-1.15	1276791	1106971	protein folding	cytoplasmic chaperonin subunit
YDR264C	AKR1______	-1.20	319834	265672	signaling, pheromone pathway; endocytosis; cell shape control	ankyrin-containing protein
YEL048C	__________	-1.31	165698	126363	unknown	unknown
YGR066C	__________	-1.07	116634	108923	unknown	unknown; similar to Vid24p
YHR080C	__________	-1.00	149993	149278	unknown	unknown; similar to Yfl042p
YJR112W	NNF1______	-1.17	441936	378412	mitosis	nuclear envelope protein
YLR261C	__________	+1.11	324192	360475	unknown	unknown
YML132W	COS3______	+1.49	1060052	1583213	unknown	unknown; similar to subtelomerically-encoded proteins
YNL047C	__________	-1.06	166059	157121	unknown	unknown; similar to Ask10p
YOR165W	__________	-1.06	233705	219584	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YPL143W	RPL33A____	+1.07	2569832	2739200	protein synthesis	ribosomal protein L33A
YAL060W	__________	-1.08	423926	392552	unknown	unknown; similar to alcohol/sorbitol dehydrogenase
YBR226C	__________	-1.15	90802	78811	unknown	unknown
YDR097C	MSH6______	-1.15	158804	137993	DNA repair	MutS homolog; mismatch repair
YDR464W	SPP41_____	-1.08	113361	105200	splicing	negative regulator of spliceosome genes
YER154W	OXA1______	-1.23	534712	434927	respiration	cytochrome c oxidase assembly
YGL157W	__________	-1.06	291909	274278	unknown	unknown; similar to tomato dihydroflavonol 4-reductase
YGR264C	MES1______	-1.16	1216729	1045441	protein synthesis	tRNA synthetase, methionyl
YIL060W	__________	-1.08	7807524	7234161	unknown	unknown
YJL158C	CIS3______	+1.63	5795684	9431195	unknown	unknown; overexpression suppresses cik1 deletion
YKL154W	SRP102____	+1.15	1008798	1164635	secretion	signal recognition particle subunit
YLR088W	GAA1______	-1.17	201431	172782	protein processing	GPI:protein transamidase component
YLR458W	__________	-1.02	137550	135177	unknown	unknown
YMR191W	__________	+1.39	293534	408849	unknown	unknown
YNL249C	MPA43_____	+1.07	210015	224941	unknown	unknown; similar to YDR109c
YOL153C	__________	+1.04	172926	180568	unknown	unknown
YOR363C	PIP2______	-1.01	155243	154445	peroxisome proliferation	transcription factor
YPR060C	ARO7______	+1.01	539406	543095	aromatic amino acid biosynthesis	chorismate mutase
YBR038W	CHS2______	-1.07	94859	89026	cell wall biogenesis	chitin synthase II
YCL061C	__________	-1.04	645635	620933	unknown	unknown
YDL155W	CLB3______	-1.16	429630	370131	cell cycle	G2/M cyclin
YDR276C	PMP3______	+1.25	1257078	1566633	salt tolerance (putative)	unknown
YEL059W	__________	-1.09	155738	143024	unknown	unknown
YGR078C	PAC10_____	-1.04	645817	619417	cytoskeleton	non-native actin binding complex subunit
YHR092C	HXT4______	-1.11	146716	132153	transport	hexose permease
YJR124C	__________	-1.25	523438	417661	unknown	unknown; similar to multidrug resistance proteins
YLR272C	YCS4______	-1.09	186069	170053	mitosis, sister chromatid cohesion	cohesin complex component
YMR011W	HXT2______	-1.18	1863734	1584052	transport	hexose permease
YNL057W	__________	-1.12	273578	243510	unknown	unknown
YOR177C	__________	+1.15	139808	160289	unknown	unknown
YPL155C	KIP2______	-1.08	161437	149497	cytoskeleton (putative)	kinesin-related protein
YAR003W	__________	-1.10	140248	128034	unknown	unknown
YBR238C	__________	-1.20	251381	210281	unknown	unknown
YDR107C	__________	+1.04	155431	161216	unknown	unknown; similar to Emp70p
YDR476C	__________	-1.20	289993	240755	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YER164W	CHD1______	-1.20	363467	301771	transcription	chromodomain-helicase-DNA-binding (CHD) family
YGL169W	SUA5______	-1.25	497755	399372	protein synthesis	translation initiation protein
YGR276C	RNH70_____	-1.12	530847	475782	DNA replication (putative)	ribonuclease H
YIL070C	MAM33_____	-1.22	385464	317189	respiration	mitochondrial acidic matrix protein
YJL170C	ASG7______	-1.07	132140	123399	unknown	unknown
YKL166C	TPK3______	-1.25	204916	163578	signaling, nutrient control of cell growth	cAMP-dependent protein kinase catalytic subunit
YLR100W	ERG27_____	+1.14	1777218	2018040	sterol metabolism	3-keto sterol reductase
YMR202W	ERG2______	-1.07	1617619	1512267	sterol metabolism	C-8 sterol isomerase
YNL261W	ORC5______	-1.07	339450	317824	DNA replication	origin recognition complex, 50 kD subunit
YOL165C	AAD15_____	+1.04	409612	425084	unknown	hypothetical aryl-alcohol dehydrogenase
YOR375C	GDH1______	-1.10	714316	646773	glutamate biosynthesis	glutamate dehydrogenase
YPR072W	NOT5______	-1.06	358333	339513	transcription	global negative regulator cpmplex component
YBR050C	REG2______	+1.22	120170	146555	glucose repression	(putative) Glc7p regulatory subunit
YCL076W	__________	-1.11	110703	100052	unknown	unknown
YDL167C	NRP1______	-1.24	360886	290482	unknown	unknown
YDR288W	__________	+1.10	297928	327784	unknown	unknown
YEL071W	DLD3______	+1.12	728341	813348	pyruvate metabolism	D-lactate dehydrogenase
YGR090W	__________	-1.15	331560	287522	unknown	unknown
YHR104W	GRE3______	+1.01	411519	415151	unknown	induced by osmotic stress
YJR136C	__________	-1.05	219086	209083	unknown	unknown
YLR284C	ECI1______	+1.02	160061	163095	unknown	putative enoyl-CoA hydratase, peroxisomal
YMR023C	MSS1______	+1.13	168466	191082	protein synthesis (putative)	mitochondrial GTPase; COX1 expression
YNL069C	RPL16B____	-1.12	9897224	8820075	protein synthesis	ribosomal protein L16B
YOR189W	__________	+1.17	378280	442921	unknown	unknown
YPL167C	REV3______	+1.07	129890	138762	DNA repair	polymerase zeta subunit
YAR028W	__________	+1.07	236608	252153	unknown	unknown; similar to subtelomerically-encoded proteins
YBR250W	__________	-1.02	115596	113662	unknown	unknown
YDR119W	__________	-1.17	1274227	1085090	unknown	unknown; similar to human cystic fibrosis
YDR488C	PAC11_____	-1.26	192693	152561	unknown	unknown; required in absence of Cin8p
YER174C	GRX4______	-1.10	537428	488046	oxidative stress response	glutaredoxin
YGL181W	GTS1______	+1.03	421224	434167	heat shock, flocculation, and bud emergence	transcription factor
YGR288W	MAL13_____	-1.18	179529	152430	maltose utilization	regulator of maltose metabolic genes
YJL182C	__________	-1.12	114000	101609	unknown	unknown
YKL178C	STE3______	-1.23	2375117	1937186	mating	a-factor receptor
YLR112W	__________	-1.50	189823	126512	unknown	unknown
YMR214W	SCJ1______	-1.06	553901	521638	unknown	unknown; similar to E. coli DnaJ
YNL273W	TOF1______	-1.04	345132	330748	unknown	topoisomerase I interacting factor
YOR011W	__________	+1.10	186786	205556	unknown	ATP-binding cassette (ABC) superfamily
YOR387C	__________	+1.02	162729	166149	unknown	unknown
YPR084W	__________	+1.02	232714	237460	unknown	unknown
YBR062C	__________	+1.11	255687	284802	unknown	unknown
YCLX12W	__________	-1.23	262873	213444
YDL179W	PCL9______	-1.12	209491	187162	cell cycle	cyclin (Pho85p)
YDR300C	PRO1______	-1.10	433571	395580	proline biosynthesis	glutamate 5-kinase
YER005W	YND1______	-1.17	279583	238040	protein glycosylation (putative)	apyrase (NDPase/NTPase)
YGR102C	__________	+1.05	340750	359288	unknown	unknown
YHR116W	__________	-1.16	334793	289299	unknown	unknown
YJR148W	BAT2______	-1.40	1620754	1154154	branched chain amino acid biosynthesis	transaminase
YLR295C	ATP14_____	+1.07	346026	369387	ATP synthesis	F1F0-ATPase complex, subunit h
YMR034C	__________	+1.13	154894	174560	unknown	unknown
YNL081C	__________	+1.25	435036	543302	unknown	unknown; similar to mitochondrial ribosomal protein S13 of
YOR199W	__________	+1.04	183464	190007	unknown	unknown
YPL179W	PPQ1______	-1.23	428584	349689	translational regulation	protein phosphatase
YBL001C	ECM15_____	+1.41	672275	950192	cell wall biogenesis	unknown
YBR262C	__________	+1.01	416668	420514	unknown	unknown
YDL001W	__________	-1.22	254288	208151	unknown	unknown; similar to Yfr048p
YDR131C	__________	-1.22	158734	130545	unknown	unknown
YDR500C	RPL37B____	-1.06	8023142	7553747	protein synthesis	ribosomal protein L37B
YFL-TYA	TY2A______	+1.01	244379	246443
YGL193C	__________	+1.01	290288	294542	unknown	unknown
YHL001W	RPL14B____	+1.17	15382837	17940944	protein synthesis	ribosomal protein L14B
YIL092W	__________	-1.13	307551	271868	unknown	unknown
YJL194W	CDC6______	-1.16	486993	418060	DNA replication	pre-initiation complex formation
YKL190W	CNB1______	+1.06	827239	873276	signaling	calcineurin regulatory B subunit
YLR124W	__________	-1.15	106615	92590	unknown	unknown
YML001W	YPT7______	+1.03	188886	193784	endocytosis	GTP-binding protein, rab family
YMR226C	__________	+1.25	1619836	2024521	unknown	unknown; similar to insect-type alcohol dehydrogenase,
YOR023C	AHC1______	-1.01	336990	333231	chromatin structure	histone acetyltransferase complex subunit
YPL001W	HAT1______	+1.09	375814	409023	chromatin structure	histone acetyltransferase complex subunit
YPR096C	__________	-1.21	128710	106094	unknown	unknown
YBR074W	__________	-1.63	253634	155392	unknown	unknown; similar to Ape3p (aminopeptidase Y)
YCR012W	PGK1______	-1.57	9950413	6321682	glycolysis	phosphoglycerate kinase
YDL191W	RPL35A____	+1.03	5972627	6159629	protein synthesis	ribosomal protein L35A
YDR312W	SSF2______	-1.15	937071	812833	signaling (putative)	suppresses G-protein beta subunit mutation
YGL001C	ERG26_____	-1.09	297202	272785	sterol metabolism	sterol C-3 dehydrogenase
YGR112W	SHY1______	+1.01	192228	194216	respiration	unknown
YHR128W	FUR1______	-1.49	1643833	1101471	pyrimidine salvage pathway	uracil phosphoribosyltransferase
YJL001W	PRE3______	+1.45	1089355	1584841	protein degradation	20S proteasome subunit (beta1)
YKL001C	MET14_____	-1.05	139161	132746	sulfate assimilation	adenylylsulfate kinase
YLL001W	DNM1______	+1.05	337941	354965	endocytosis	dynamin-related protein
YLR307W	CDA1______	+1.01	110365	111029	sporulation	chitin deacetylase
YNL093W	YPT53_____	-1.00	108083	107959	endocytosis	GTP-binding protein, rab family
YOL001W	PHO80_____	+1.12	255624	287516	cell cycle	cyclin (Pho85p)
YOR211C	MGM1______	+1.01	130187	131939	mitochondrial genome maintenance	dynamin family protein
YPL190C	NAB3______	-1.03	592632	575256	mRNA splicing	nuclear polyadenylated RNA-binding protein
YAR050W	FLO1______	-1.03	111485	108720	flocculation	cell wall protein
YBL011W	SCT1______	-1.27	186640	147002	unknown	suppresses a choline-transport mutant
YBR274W	CHK1______	-1.19	203334	171500	cell cycle	DNA damage checkpoint protein kinase
YDL013W	HEX3______	-1.23	205668	167439	hexose metabolism (putative)	unknown
YDR143C	SAN1______	-1.42	199004	140629	silencing	(putative) transcriptional regulator
YDR512C	__________	+1.16	362896	419901	unknown	unknown
YFL010C	__________	-1.10	1245147	1135122	unknown	unknown
YGL205W	POX1______	-1.04	140071	135150	fatty acid metabolism	acyl-CoA oxidase
YHL009C	YAP3______	-1.10	206924	188056	transcription	basic leu zipper transcription factor
YIL103W	__________	-1.01	432862	427241	unknown	unknown; similar to diptheria toxin resistance protein
YJL206C	__________	+1.05	149307	157421	unknown	unknown; similar to Put3p and other transcription
YKL202W	__________	+1.03	116741	119666	unknown	unknown
YLR136C	TIS11_____	+1.32	115457	152041	unknown	unknown
YML011C	__________	+1.03	249569	256120	unknown	unknown
YMR238W	DFG5______	+1.94	615934	1192121	pseudohyphal growth	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL295W	__________	-1.06	165129	155177	unknown	unknown
YOR035C	SHE4______	-1.02	194713	191041	asymmetric HO expression	unknown
YPL013C	__________	+1.20	453541	543746	protein synthesis	ribosomal protein, mitochondrial S16
YPR108W	RPN7______	-1.07	750134	699197	protein degradation	26S proteasome regulatory subunit
YBR085W	AAC3______	-1.76	309123	175167	transport	mitochondrial ADP/ATP translocator
YCR023C	__________	-1.24	263992	212831	unknown	major facilitator superfamily
YDL203C	__________	-1.46	184998	126398	unknown	unknown
YDR322W	MRPL35____	-1.35	267717	197578	protein synthesis	ribosomal protein, mitochondrial L35
YER025W	GCD11_____	-1.51	1762352	1163469	protein synthesis	translation initiation factor eIF2 gamma subunit
YGL013C	PDR1______	-1.19	212457	177920	transport	transcription factor, regulates ABC transporters
YGR124W	ASN2______	-1.19	2166161	1822811	asparagine biosynthesis	asparagine synthetase
YHR139C	SPS100____	-1.06	162571	153634	sporulation	spore wall maturation protein
YJL013C	MAD3______	-1.14	389220	341744	cell cycle	spindle checkpoint complex subunit
YKL012W	PRP40_____	+1.05	255501	268358	mRNA splicing	U1 snRNP protein
YLL013C	__________	-1.32	438437	331441	unknown	unknown; similar to Drosophila pumilio protein
YLR318W	EST2______	-1.05	197534	187262	telomere length regulation	telomerase catalytic subunit
YMR055C	BUB2______	-1.00	158649	158623	cell cycle, checkpoint	unknown
YNL105W	__________	-1.12	111094	99594	unknown	unknown
YOL013C	HRD1______	+1.03	203935	209045	protein degradation	unknown; required to degrade misfolded ER lumenal and integral membrane proteins
YOR223W	__________	+1.11	314316	349320	unknown	unknown; similar to class II family of aminoacyl-tRNA
YPL202C	__________	-1.15	338231	294261	unknown	unknown; similar to Rcs1p
YAR073W	IMD1______	-1.83	1589892	867351	unknown	unknown; similar to Pur5p, may be an inosine-5'-monophosphate dehydrogenase
YBL023C	MCM2______	-1.25	306363	244986	DNA replication	MCM initiator complex
YBR286W	APE3______	-1.28	1021727	796001	protein degradation	vacuolar aminopeptidase Y
YDL025C	__________	-1.15	158568	138338	unknown	putative protein kinase
YDR155C	CPH1______	-1.13	971409	859285	protein folding	peptidyl-prolyl cis-trans isomerase
YDR524C	AGE1______	-1.07	317637	295719	secretion	GTPase activating protein for ARFs
YFL019C	__________	-1.15	131847	114593	unknown	unknown
YGL217C	__________	-1.16	146527	126733	unknown	unknown; similar to mouse kinesin-related protein KIF3
YHL021C	__________	+1.24	219555	272860	unknown	unknown
YIL115C	NUP159____	+1.04	614538	636468	nuclear protein targeting	nuclear pore protein
YJL218W	__________	-1.06	184356	174270	unknown	unknown; similar to E. coli galactoside O-acetyltransferase
YKL214C	__________	-1.12	372221	332697	unknown	unknown
YLR148W	PEP3______	-1.07	274289	255878	vacuole biogenesis	vacuolar membrane protein
YML022W	APT1______	-1.18	1501334	1273708	purine biosynthesis	adenine phosphoribosyltransferase
YMR251W	__________	+1.00	132388	132534	unknown	unknown
YNL307C	MCK1______	-1.20	601546	499547	meiosis	protein kinase
YOR047C	STD1______	-1.09	510151	470140	glucose repression	modulator of glucose repression
YPL025C	__________	-1.23	340903	276789	unknown	unknown
YPR120C	CLB5______	+1.01	202241	204551	cell cycle	G1/S cyclin
YBR096W	__________	+1.12	651741	730946	unknown	unknown
YCR033W	__________	-1.17	120787	103520	unknown	unknown
YDL215C	GDH2______	-1.25	141994	113753	glutamate metabolism	NAD-dependent glutamate dehydrogenase
YDR334W	SWR1______	-1.09	264408	243688	RNA processing (putative)	RNA helicase (putative)
YER037W	__________	+1.47	148416	217597	unknown	unknown
YGL025C	PGD1______	-1.02	924421	906515	transcription	RNA polymerase II mediator subunit
YGR136W	__________	+1.06	749473	797762	unknown	unknown
YHR149C	__________	-1.11	240155	216478	unknown	unknown
YJL025W	RRN7______	-1.07	232480	217795	transcription	component of rDNA transcription factor
YKL024C	URA6______	-1.09	1115862	1021544	pyrimidine metabolism	uridine-monophosphate kinase
YLL025W	__________	+1.05	306288	322251	unknown	unknown; similar to Pau3p and members of the PAU1 family
YLR330W	CHS5______	-1.01	745111	738039	cell wall biogenesis	unknown
YMR067C	__________	+1.10	340679	375561	unknown	unknown
YNL117W	MLS1______	+1.00	145546	145991	glyoxylate cycle	malate synthase
YOL025W	LAG2______	-1.03	164885	160667	aging	unknown
YOR235W	__________	-1.02	177245	173088	unknown	unknown
YPL214C	THI6______	+1.04	329431	342062	thiamine biosynthesis	TMP pyrophosphorylase, hydroxyethylthiazole kinase
YER186C	__________	+1.03	498911	512577	unknown	unknown
YBL035C	POL12_____	-1.13	131049	116393	DNA replication	DNA polymerase alpha, 70 kD subunit
YBR298C	MAL31_____	-1.06	99010	93822	transport	maltose permease
YDL037C	__________	-1.17	105998	90806	unknown	similar to glucan 1,4-alpha-glucosidase
YDR167W	TAF25_____	+1.08	518229	559748	transcription	TFIID 23 kD subunit
YDR536W	STL1______	-1.10	145751	132866	transport	hexose transporter (putative)
YFL030W	__________	+1.05	150093	158187	unknown	unknown; similar to Methanobacterium aspartate transaminase
YGL228W	SHE10_____	-1.00	441561	440982	unknown	causes lethality when overexpressed
YHL032C	GUT1______	+1.02	238968	242905	glycerol utilization	glycerol kinase
YIL127C	__________	-1.17	677611	578588	unknown	unknown
YJR006W	HYS2______	+1.07	377520	404478	DNA replication	polymerase delta 55 KD subunit
YKR001C	VPS1______	-1.10	587533	534928	vacuolar protein targeting	GTPase, dynamin family
YLR158C	ASP3-3____	+1.08	141684	153477	asparagine utilization	L-asparaginase II
YML033W	__________	+1.22	282201	344539
YMR262W	__________	-1.15	391642	340078	unknown	unknown
YNL319W	__________	-1.23	346073	281106	unknown	unknown
YOR059C	__________	-1.07	584653	548421	unknown	unknown
YPL037C	EGD1______	+1.12	6625120	7387928	transcription	regulator of pol II transcribed genes; enhances Gal4 DNA binding
YPR132W	RPS23B____	+1.20	15710343	18851414	protein synthesis	ribosomal protein S23B
YBR108W	__________	+1.14	224893	255646	unknown	unknown; similar to wheat glutenin, secalin
YCR045C	__________	-1.19	127835	106975	unknown	unknown; similar to protease B (Prb1p) and subtilisin family
YDL227C	HO________	-1.17	85484	73328	mating type switching	homothallic switching endonuclease
YDR346C	__________	-1.57	1075896	684977	unknown	unknown
YGL037C	PNC1______	+2.36	282860	667596	pyridine nucleotide cycle	pyrazinamidase and nicotinamidase
YGR148C	RPL24B____	+1.20	15812855	19033610	protein synthesis	ribosomal protein L24B
YHR161C	YAP1801___	+1.03	1175276	1213341	endocytosis and secretion	clathrin assembly protein
YJL037W	__________	-1.47	248916	169382	unknown	unknown
YKL035W	UGP1______	-1.01	450374	444403	pyrimidine metabolism	UGP1, UDP-glucose pyrophosphorylase
YLL037W	__________	+1.02	592427	605600	unknown	unknown; similar to human platelet-activating factor
YLR342W	FKS1______	+1.37	1771440	2428403	cell wall biogenesis	1,3-beta-D-glucan synthase subunit
YMR078C	CTF18_____	-1.08	226022	209876	mitosis, chromosome transmission	unknown
YNL129W	__________	-1.01	171286	169960	unknown	unknown
YOL037C	__________	-1.08	282712	261734	unknown	unknown
YOR247W	SRL1______	+1.36	3592658	4900333	unknown	unknown; similar to Svs1p; suppressor of Rad53 lethality
YPL226W	NEW1______	-1.41	959329	680356	unknown	unknown; similar to members of the ATP-binding cassette (AC); prion
YHR218W	__________	-1.11	214474	193283	unknown	unknown; similar to other subtelomerically-encoded proteins
YBL047C	__________	-1.38	139968	101160	unknown	unknown; similar to Uso1p, Pan1p, and mouse eps15
YDL049C	KNH1______	+1.02	100688	103030	cell wall biogenesis	Kre9p homolog
YDR177W	UBC1______	+1.17	749774	873529	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YFL040W	__________	-1.05	130100	123460	unknown	unknown; similar to members of the sugar transport family
YGL240W	DOC1______	-1.09	184455	169054	cell cycle	anaphase-promoting complex subunit
YHL044W	__________	+1.04	139979	146201	unknown	unknown; similar to subtelomerically-encoded proteins
YIL139C	REV7______	+1.11	276455	305588	DNA repair	DNA polymerase zeta

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YJR017C	ESS1______	-1.23	517926	419379	protein folding	peptidyl-prolyl cis/trans isomerase
YKR013W	PRY2______	+1.26	1353077	1711473	unknown	unknown; similar to plant PR-pathogen related proteins
YLR170C	APS1______	+1.17	345957	403148	secretion	AP-1 complex subunit
YML043C	RRN11_____	-1.01	263013	259252	transcription	component of rDNA transcription factor
YMR274C	RCE1______	+1.03	232869	240820	protein processing	protease, acts on Ras and a-factor C-termini
YNL331C	AAD14_____	-1.07	345797	322013	unknown	hypothetical aryl-alcohol dehydrogenase
YOR071C	__________	-1.13	291215	258365	transport	thiamine transporter (putative)
YPL049C	DIG1______	-1.06	698450	657433	invasive growth	MAP kinase-associated protein
YPR142C	__________	-1.32	483618	365969	unknown	unknown
YBR119W	MUD1______	+1.12	267753	299363	mRNA splicing	U1 snRNP A protein
YCR057C	PWP2______	-1.82	221044	121319	cytoskeleton (putative)	unknown
YDL239C	__________	-1.08	132766	122483	unknown	unknown
YDR358W	GGA1______	+1.02	148862	152146	secretion (putative)	unknown; binds ARF
YER057C	HIG1______	+1.45	780443	1129345	heat shock response	heat-induced protein
YGL049C	TIF4632___	-1.07	181966	170225	protein synthesis	mRNA cap-binding protein (eIF-4F) subunit
YGR160W	__________	-2.08	839142	403796	unknown	unknown
YHR173C	__________	+1.17	220541	257471	unknown	unknown
YJL050W	MTR4______	-1.58	773331	490603	mRNA export	RNA helicase
YKL047W	__________	+1.09	266089	288770	unknown	unknown
YLL049W	__________	+1.31	423419	553968	unknown	unknown
YLR354C	TAL1______	+1.25	2045678	2558970	pentose phosphate cycle	transaldolase
YMR089C	YTA12_____	-1.17	161861	138546	protein folding	mitochondrial chaperonin
YNL141W	AAH1______	-1.34	978877	729277	purine metabolism	adenine deaminase
YOL049W	GSH2______	+1.12	896437	1007595	glutathione biosynthesis	glutathione synthetase
YOR259C	RPT4______	+1.32	506125	667745	protein degradation	26S proteasome regulatory subunit
YPL238C	__________	-1.58	313675	198280	unknown	unknown
YJR160C	__________	-1.01	115685	114686	unknown	unknown; similar to maltose permeases (maltose/H+
YBL059W	__________	+1.02	199785	203777	unknown	unknown
YDL061C	RPS29B____	+1.03	8066973	8344565	protein synthesis	ribosomal protein S29B
YDR188W	CCT6______	-1.19	1397629	1177968	protein folding	cytoplasmic chaperonin complex
YFL052W	__________	-1.18	155669	131603	unknown	unknown; similar to MAL regulatory proteins
YGL252C	RTG2______	-1.11	581795	524457	interorganelle communication	unknown
YHR004C	NEM1______	-1.06	244284	229467	nuclear organization and biogenesis	phosphatase
YIL151C	__________	-1.08	741595	688903	unknown	unknown; similar to mitochondrial aldehyde dehydrogenase
YJR028W	__________	-1.08	3210692	2978053	transposition	TyA gag protein
YKR025W	RPC37_____	-1.24	869307	700877	transcription	RNA polymerase III 37 kDa subunit
YLR182W	SWI6______	-1.17	301331	257727	cell cycle	transcription factor
YML053C	__________	+1.20	308611	371320	unknown	unknown
YNR004W	__________	+1.12	179868	200776	unknown	unknown; similar to bovine interferon gamma precursor
YOR083W	__________	-1.13	181900	160859	unknown	unknown
YPR154W	__________	-1.07	105276	98034	unknown	unknown; similar to several SH3 domain-containing proteins
YBR131W	CCZ1______	-1.14	140182	123045	calcium, caffeine, and zinc sensitivity	unknown
YDR003W	__________	+1.03	124933	128967	unknown	unknown; similar to Ybr005p
YDR368W	YPR1______	+1.18	659629	775468	unknown	unknown; similar to aldo-keto reductases
YER067W	__________	+1.17	163454	191043	unknown	unknown
YGL061C	DUO1______	-1.02	227556	223079	mitosis	unknown; spindle protein
YGR168C	__________	+1.07	169349	180662	unknown	unknown; similar to human vasoactive intestinal peptide
YHR185C	ADY1______	+1.02	106133	108499	meiosis (putative)	unknown
YJL062W	LAS21_____	-1.09	354695	324370	unknown	major facilitator superfamily
YKL059C	__________	-1.04	221243	213464	unknown	unknown; similar to members of the chaperonin-containing
YLL061W	MMP1______	+1.00	773323	777002	transport, amino acid	high affinity S-methylmethionine permease
YLR366W	__________	-1.09	99395	91581	unknown	unknown
YMR101C	SRT1______	-1.07	122668	114124	protein glycosylation	cis-prenytransferase (putative)
YNL153C	GIM3______	-1.04	618082	592750	protein folding	prefoldin subunit 4
YOL059W	GPD2______	-1.18	586122	496458	glycerol metabolism	glycerol-3-phosphate dehydrogenase
YOR271C	__________	-1.15	1024007	891598	unknown	unknown; similar to rat tricarboxylate carrier
YBL071C	__________	-1.05	305761	290886	unknown	unknown
YDL073W	__________	-1.05	135026	128976	unknown	unknown
YDR200C	__________	-1.01	204240	201321	unknown	unknown
YFL064C	__________	-1.30	209204	160896	unknown	unknown; similar to other subtelomerically-encoded proteins
YGR001C	__________	+1.00	878921	880577	unknown	unknown
YHR015W	MIP6______	-1.05	151717	143978	mRNA export, putative	RNA-binding protein
YIL162W	SUC2______	-1.34	434080	323059	sucrose utilization	invertase
YJR040W	GEF1______	-1.01	426401	422136	transport	CLC chloride channel, iron transporter
YKR037C	SPC34_____	+1.06	278988	296249	cytoskeleton	spindle pole body component
YLR194C	__________	+2.55	745390	1897121	unknown	unknown
YML064C	TEM1______	-1.11	351816	315599	cell cycle	GTP-binding protein, RAS superfamily
YMR296C	LCB1______	-1.19	805674	678876	sphinogolipid metabolism	serine palmitoyltransferase component
YNR016C	ACC1______	-1.02	138170	135507	fatty acid metabolism	acetyl-CoA carboxylase
YOR095C	RKI1______	-1.54	1279558	829310	pentose phosphate cycle	ribose-5-phosphate ketol-isomerase
YPL071C	__________	+1.18	314561	372364	unknown	unknown
YPR162C	ORC4______	-1.10	261531	238125	DNA replication	origin recognition complex 56 kD subunit
YBR143C	SUP45_____	-1.24	868314	701985	protein synthesis	translation release factor eRF1 subunit
YCR081W	SRB8______	-1.11	120387	108543	transcription	RNA polymerase II mediator subunit
YDR015C	__________	+1.01	107348	108264	unknown	unknown
YDR380W	__________	+1.03	222204	228362	unknown	unknown; similar to pyruvate decarboxylase, pyruvate
YER077C	__________	+1.11	207671	229551	unknown	unknown; similar to class I tRNA synthetases
YGL073W	HSF1______	+1.01	140921	142261	heat shock	transcription factor
YGR180C	RNR4______	+1.08	877073	945695	DNA replication	ribonucleotide reductase
YHR197W	__________	-1.34	510297	382160	unknown	unknown
YJL074C	SMC3______	-1.13	232586	206175	chromatin structure	cohesin
YKL071W	__________	-1.05	200345	191502	unknown	unknown
YLR006C	SSK1______	-1.07	227147	212826	signaling	two-component pathway
YLR378C	SEC61_____	-1.21	1278215	1059155	secretion	ER protein translocation complex subunit
YMR113W	FOL3______	-1.02	316084	308955	folate metabolism	dihydrofolate synthetase
YNL165W	__________	-1.01	304490	301812	unknown	unknown
YOL071W	__________	+1.22	259262	315597	unknown	unknown
YOR283W	__________	+1.01	645900	654143	unknown	unknown; similar to phosphoglycerate mutases
YPL259C	APM1______	+1.05	354387	373278	secretion	AP-1 complex subunit
YBL083C	__________	+1.10	325992	359011	unknown	unknown
YDL085W	__________	+1.04	139323	144386	unknown	unknown; similar to NADH dehydrogenase (ubiquinone)
YFR008W	__________	-1.14	600580	528287	unknown	unknown
YGR013W	SNU71_____	-1.20	186351	155670	mRNA splicing	U1 snRNP protein
YHR026W	PPA1______	-1.00	3192932	3190273	vacuolar acidification	vacuolar H+-ATPase proteolipid protein
YIL173W	VTH1______	-1.02	326596	319029	vacuolar protein targeting	unknown; similar to Vps10p
YJR052W	RAD7______	+1.03	288309	296219	DNA repair, nucleotide excision	NEF4 component
YKR049C	__________	+1.21	223472	271383	unknown	unknown
YLR206W	ENT2______	-1.05	96680	92067	endocytosis (putative)	unknown; epsin homolog
YML076C	__________	-1.05	170542	162338	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YNR028W	CPR8______	-1.08	392282	362126	protein folding	peptidyl-prolyl cis-trans isomerase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOR107W	RGS2______	-1.08	226589	208960	signaling	GTPase-activating protein (GAP) for Gpa2p
YPL083C	SEN54_____	+1.07	456205	488456	tRNA splicing	splicing endonuclease subunit
YPR174C	__________	-1.03	157906	152836	unknown	unknown; similar to C. elegans nuclear lamin
YBR155W	CNS1______	-1.39	730958	526447	unknown	unknown; similar to Sti1p; suppresses cyclophilin mutant
YCR092C	MSH3______	-1.09	251528	230490	DNA repair, mismatch	MutS homolog
YDR027C	LUV1______	-1.01	540058	533170	vacuole biogenesis (putative)	unknown
YDR392W	SPT3______	-1.00	340966	339652	chromatin structure	histone acetyltransferase complex subunit
YER088C	DOT6______	+1.04	388028	401843	silencing (telomere)	nuclear protein with Myb DNA-binding domain
YGL085W	__________	+1.06	254262	268623	unknown	unknown; similar to Staphylococcus hyicus thermonuclease
YGR192C	TDH3______	+1.20	15927761	19104076	glycolysis	glyceraldehyde-3-phosphate dehydrogenase 3
YHR209W	__________	+1.03	4273996	4383645	unknown	unknown; similar to Yer175p
YJL086C	__________	-1.01	241329	239240	unknown	unknown
YKL083W	__________	-1.25	236732	189672	unknown	unknown
YLR018C	POM34_____	-1.71	609825	355684	nuclear protein targeting	nuclear pore protein
YLR390W	ECM19_____	+1.16	248489	287715	cell wall biogenesis	unknown
YMR124W	__________	+1.12	695557	778880	unknown	unknown
YNL177C	__________	+1.01	532123	536300	unknown	unknown
YOL083W	__________	+1.06	162989	172266	unknown	unknown
YOR295W	__________	+1.05	326092	343785	unknown	unknown
YPL271W	ATP15_____	+1.27	510023	649386	ATP synthesis	F1-ATP synthase epsilon subunit
YAL002W	VPS8______	-1.17	234551	199879	vacuolar protein targeting	unknown
YBR167C	POP7______	+1.03	217006	223023	rRNA and tRNA processing	RNase P and RNase MRP subunit
YCR104W	PAU3______	-1.14	198468	173701	unknown	unknown; similar to bovine alcohol dehydrogenase
YDR038C	ENA5______	-1.26	360590	286092	transport	Na(+) ATPase
YDR405W	MRP20_____	-1.32	241742	183505	protein synthesis	ribosomal protein, mitochondrial L23
YER100W	UBC6______	-1.15	576842	502580	protein degradation, ubiquitin-mediated	ubiquitin-conjugating enzyme
YGL098W	__________	-1.03	237117	230660	unknown	unknown
YGR205W	__________	+1.10	154900	169924	unknown	unknown; similar to E. coli putrescine transport protein
YIL002C	INP51_____	+1.04	258675	270284	phosphatidylinositol metabolism	phosphatidylinositol 4,5-bisphosphate 5-phosphatase
YJL099W	CHS6______	+1.20	182022	218897	cell wall biogenesis	chitin biosynthesis
YKL096W	CWP1______	+4.33	1750592	7576937	cell wall protein	beta-1,6-glucan acceptor
YLR031W	__________	+1.33	125681	166721	unknown	unknown
YLR403W	SFP1______	-1.15	200984	174947	unknown	overexpression inhibits nuclear protein localization
YMR136W	GAT2______	+1.27	202457	256549	transcription (putative)	transcription factor (putative_; GATA zinc finger protein
YNL190W	__________	-1.34	2513462	1881159	unknown	unknown
YOL096C	COQ3______	+1.05	212474	222533	ubiquinone biosynthesis	3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
YOR306C	__________	+1.16	355978	414431	unknown	unknown; similar to human X-linked PEST-containing
YPR001W	CIT3______	-1.09	135964	124250	TCA cycle	citrate synthase
YBL096C	__________	-1.20	128889	107624	unknown	unknown
YDL098C	SNU23_____	-1.12	236425	210886	mRNA splicing (putative)	U4/U6.U5 snRNP protein
YDR221W	__________	-1.14	180082	158335	unknown	unknown; similar to the beta subunit of human glucosidase
YEL002C	WBP1______	-1.19	271305	227853	protein glycosylation	oligosaccharyltransferase complex subunit
YFR021W	__________	-1.25	186568	149446	unknown	unknown
YGR026W	__________	+1.24	568485	704379	unknown	unknown
YHR039C	VMA10_____	+1.24	2120402	2620741	vacuolar acidification	vacuolar H-ATPase 13 kDa subunit
YIR009W	MSL1______	+1.01	205584	208278	mRNA splicing	U2 snRNP protein
YJR065C	ARP3______	+1.12	968253	1082547	cytoskeleton	actin-related protein
YKR062W	TFA2______	+1.17	379205	442655	transcription	TFIIE 43 kD subunit
YLR219W	__________	-1.01	174764	173607	unknown	unknown
YML089C	__________	-1.00	111935	111490	unknown	unknown
YNL002C	RLP7______	-1.15	1118905	973441	protein synthesis	ribosomal protein L7 (putative)
YNR041C	COQ2______	-1.12	385950	345037	ubiquinone biosynthesis	para-hydroxybenzoate polyprenyltransferase
YOR120W	GCY1______	+1.14	227382	259396	unknown	unknown; similar to mammalian aldo-keto reductases
YPL096W	PNG1______	-1.00	283974	282935	protein modification	peptide:N-glycanase
YPR187W	RPO26_____	+1.10	2668585	2935338	transcription	Shared subunit of RNA polymerases I, II, and III
YAL015C	NTG1______	-1.61	226602	141154	DNA repair	DNA glycosylase
YBR179C	FZO1______	-1.31	264500	201510	mitochondrial biogenesis	mitochondrial membrane GTPase
YCRX09C	__________	-1.79	305528	171030
YDR050C	TPI1______	+1.17	15881893	18543790	glycolysis	triosephosphate isomerase
YDR417C	__________	-1.65	8959390	5445737	unknown	unknown
YER112W	LSM4______	-1.05	632261	600359	mRNA splicing	U6 snRNP protein
YGL110C	__________	-1.00	429519	429049	unknown	unknown
YGR217W	CCH1______	+1.04	303623	315225	transport	(putative) Ca(2+) channel protein
YJL111W	CCT7______	-1.14	1349772	1185689	protein folding	cytoplasmic chaperonin complex
YKL107W	__________	+1.13	123445	139616	unknown	unknown
YLR041W	__________	-1.24	328641	265294	unknown	unknown
YLR413W	__________	-1.69	1185663	703613	unknown	unknown
YMR148W	__________	+1.05	229980	241042	unknown	unknown
YNL202W	SPS19_____	-1.17	143170	122626	sporulation	peroxisomal 2,4-dienoyl-CoA reductase
YOL106W	__________	-1.25	7918691	6328775	unknown	unknown
YOR318C	__________	-1.35	204129	151614	unknown	unknown
YPR013C	__________	-1.02	250763	246803	unknown	unknown; similar to mouse REX1 encoded transcription factor
YBL106C	SRO77_____	-1.02	123200	121175	secretion (putative)	unknown; homolog of Drosophila tumor suppressor l(2)gl
YCL013W	__________	-1.07	121257	113238
YDL110C	__________	+1.81	295033	532818	unknown	unknown
YDR233C	__________	-1.16	2184168	1880470	unknown	unknown
YEL014C	__________	-1.09	260437	239907	unknown	unknown
YFR032C	__________	+1.08	131169	142193	unknown	unknown
YGR036C	CAX4______	+1.02	160544	164087	cell wall biogenesis	unknown
YIR020C	__________	-1.01	170517	168753	unknown	unknown
YJR077C	MIR1______	-1.12	1152412	1025208	transport	mitochondrial phosphate transporter
YKR074W	__________	+1.20	603681	723302	unknown	unknown
YLR229C	CDC42_____	+1.14	1100572	1259199	signaling, filamentous or polarized growth	GTPase, Rho subfamily
YNL014W	__________	-1.85	721211	389028	unknown	unknown; similar to translation elongation factor Yef3p,
YNR053C	__________	-1.21	1171948	968951	unknown	unknown; similar to human breast tumor-associated
YOR132W	VPS17_____	+1.00	347965	349542	vacuolar protein targeting	peripheral membrane protein
YPL108W	__________	+1.08	262863	283043	unknown	unknown
YPR199C	ARR1______	+1.32	301992	397299	transcription	basic leu zipper transcription factor
YAL027W	__________	-1.18	337948	287368	unknown	unknown
YBR191W	RPL21A____	-1.10	12133153	11034734	protein synthesis	ribosomal protein L21A
YCRX21C	__________	-1.35	311316	230741
YDR062W	LCB2______	-1.79	414440	231129	sphingolipid biosynthesis	serine C-palmitoyltransferase subunit
YDR429C	TIF35_____	-1.31	2154510	1644168	protein synthesis	translation initiation factor eIF3 subunit
YER123W	YCK3______	-1.54	407115	264494	cell proliferation	plasma membrane-bound casein kinase I
YGL122C	NAB2______	+1.07	108635	115984	mRNA processing	poly(A)+RNA binding protein
YGR229C	SMI1______	-1.91	471616	246950	cell wall biogenesis	may regulate glucan and chitin synthesis
YIL025C	__________	-1.15	169778	147036	unknown	unknown
YJL123C	__________	-1.03	316843	306150	unknown	unknown
YKL119C	VPH2______	+1.05	255678	268642	vacuolar acidification	vacuolar H+-ATPase assembly protein
YLR053C	__________	+1.12	125145	140567	unknown	unknown; similar to xylose isomerase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL214W	PEX17_____	+1.11	165947	183405	peroxisome biogenesis	peripheral membrane protein
YOL118C	__________	-1.05	144077	137282	unknown	unknown
YOR330C	MIP1______	-1.16	368939	319183	DNA replication	mitochondrial DNA polymerase catalytic subunit
YPR025C	CCL1______	-1.00	311747	310975	transcription	TFIIH subunit
YBR005W	__________	+1.39	249563	346429	unknown	unknown
YCL026C	FRM2______	-1.13	98959	87257	signaling, fatty acid-mediated	unknown
YDL122W	UBP1______	-1.14	199133	174760	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YEL025C	SRI1______	-1.01	284199	280696	unknown	unknown; interacts with SWI/SNF and RSC
YFR042W	__________	+1.16	229589	266313	unknown	unknown
YGR043C	__________	+1.55	113212	175600	unknown	unknown; similar to Tal1p
YHR060W	VMA22_____	+1.12	391540	438155	vacuolar acidification	vacuolar H+-ATPase assembly protein
YIR030C	DCG1______	+1.25	149879	187632	unknown	may be involved in catabolite repression
YJR090C	GRR1______	-1.01	189910	187850	glucose repression (and cell cycle)	cyclin F box protein
YKR086W	PRP16_____	-1.07	503426	471765	mRNA splicing	RNA helicase
YLR241W	__________	-1.07	215488	200761	unknown	major facilitator superfamily
YML110C	COQ5______	-1.00	728210	725610	ubiquinone biosynthesis	methyltransferase
YNL026W	__________	+1.07	139342	149355	unknown	unknown
YNR065C	__________	+1.14	207638	236356	unknown	unknown; similar to Pep1p
YPL120W	VPS30_____	+1.04	202808	211450	vacuolar protein targeting	unknown?
YAL036C	FUN11_____	-1.40	380362	271786	unknown	unknown; similar to Xenopus laevis GTP-binding protein DRG
YBR203W	__________	-1.14	90049	79051	unknown	unknown
YDR074W	TPS2______	+1.05	201475	212110	trehalose metabolism	trehalose-6-phosphate phosphatase
YDR441C	APT2______	+1.10	400651	442154	purine metabolism	unknown; similar to adenine phosphoribosyltransferase
YER135C	__________	-1.08	92989	86407	unknown	unknown
YGL134W	PCL10_____	+1.05	218543	230313	cell cycle	cyclin (Pho85p)
YGR241C	YAP1802___	+1.09	257349	281461	endocytosis and secretion	clathrin assembly protein
YIL037C	__________	+1.21	137605	165986	unknown	unknown
YJL135W	__________	+1.03	95600	98425	unknown	unknown
YKL131W	__________	-1.00	97909	97619	unknown	unknown
YLR065C	__________	+1.05	696386	728390	unknown	unknown
YLR435W	__________	-1.12	896729	804087	unknown	unknown
YMR170C	ALD2______	+1.11	198556	219741	ethanol utilization	aldehyde dehydrogenase
YNL226W	__________	-1.04	115403	111102	unknown	unknown
YOL130W	ALR1______	-1.21	171050	141621	aluminum resistance	ion transporter, putative
YOR342C	__________	-1.05	550049	521688	unknown	unknown
YPR037C	__________	+1.20	567279	680679	unknown	unknown; similar to Erv1p and rat ALR protein
YBR015C	MNN2______	-1.10	496504	450589	protein glycosylation	Golgi alpha-1,2-mannosyltransferase (putative)
YCL038C	__________	-1.13	93423	82513	unknown	unknown
YDR257C	RMS1______	-1.46	319445	218548	transcription	(putative) transcriptional regulator
YEL037C	RAD23_____	-1.24	582198	467984	DNA repair, nucleotide excision	ubiquitin-like protein
YFR054C	__________	-1.13	105618	93603	unknown	unknown
YGR055W	MUP1______	+1.40	562537	787383	transport	methionine permease
YIR042C	__________	+1.32	157272	206882	unknown	unknown
YJR101W	__________	+1.08	121743	131504	unknown	unknown; similar to superoxide dismutase
YKR098C	UBP11_____	+1.13	161321	181793	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YLR253W	__________	-1.00	208646	208156	unknown	unknown; similar to Abc1p
YML121W	GTR1______	+1.08	407669	439173	phosphate transport	GTP-binding protein
YNL036W	NCE103____	+1.41	292305	413205	secretion, non-classical	unknown
YNR077C	__________	-1.03	88339	85931	unknown	unknown
YOR154W	__________	-1.16	238980	205276	unknown	unknown
YPL132W	COX11_____	+1.03	243232	251714	respiration	cytochrome-c oxidase assembly
YAL047C	SPC72_____	-1.09	192419	176250	cytoskeleton	spindle pole body component
YBR215W	HPC2______	-1.27	130744	102835	transcription	regulator of histone transcription
YDR086C	SSS1______	+1.11	1288221	1425770	secretion	ER protein translocation complex subunit
YDR453C	__________	-1.22	257760	211220	unknown	unknown; similar to Tsa1p
YER145C	FTR1______	-1.30	1112032	853208	transport	iron permease
YGL146C	__________	+1.01	122359	123616	unknown	unknown; similar to Bunyamwera virus RNA-directed RNA
YGR253C	PUP2______	+1.24	1340347	1657360	protein degradation	20S proteasome subunit(alpha5)
YIL049W	DFG10_____	+1.09	269139	294469	filamentous growth	unknown
YJL147C	__________	+1.13	216050	244716	unknown	unknown
YKL143W	LTV1______	-1.46	898697	614537	unknown	unknown; required for viability at low temperature
YLR077W	__________	-1.05	155922	148271	unknown	unknown
YLR447C	VMA6______	-1.00	2288244	2287441	vacuolar acidification	vacuolar H+-ATPase V0 domain 36 KD subunit
YMR180C	CTL1______	+1.10	225882	247490	unknown	RNA triphosphatase
YNL238W	KEX2______	+1.00	97395	97722	secretion	late Golgi endoproteinase
YOL142W	RRP40_____	-1.15	626835	545371	rRNA processing	exosome complex component
YOR352W	__________	+1.10	237501	261373	unknown	unknown
YPR049C	__________	-1.06	464981	438097	unknown	unknown
YBR027C	__________	+1.02	124768	126864	unknown	unknown
YCL050C	APA1______	-1.18	383671	325936	purine metabolism	ATP adenylyltransferase I
YDL144C	__________	+1.03	369946	379969	unknown	unknown
YDR265W	PEX10_____	-1.03	142362	138355	peroxisome biogenesis	integral membrane protein
YEL049W	PAU2______	+1.17	216924	254776	unknown	unknown; similar to members of the Srp1p/Tip1p family
YGR067C	__________	+1.05	109639	115108	unknown	unknown
YHR081W	__________	-1.14	757344	664086	unknown	unknown
YJR113C	__________	+1.02	462705	470213	protein synthesis	ribosomal protein, mitochondrial S7 (putative)
YLR262C	YPT6______	+1.06	367009	387944	secretion	GTP-binding protein, rab family
YNL048W	ALG11_____	-1.06	296744	279902	protein glycosylation	unknown
YOR166C	__________	+1.03	237860	245318	unknown	unknown
YPL144W	__________	+1.09	130446	142597	unknown	unknown
YAL061W	__________	-1.08	139496	129380	unknown	unknown; similar to alcohol/sorbitol dehydrogenase
YBR227C	MCX1______	-1.14	211293	185991	protein folding	chaperone, mitochondrial (putative)
YDR098C	GRX3______	+1.06	927034	986107	oxidative stress response	glutaredoxin
YDR465C	RMT2______	-1.39	397259	284811	arginine metabolism	arginine methyltransferase
YER155C	BEM2______	-1.07	90794	84951	bud emergence	GTPase-activating protein for Rho1p
YGL158W	RCK1______	+1.06	110313	116650	unknown	protein kinase
YGR265W	__________	-1.41	250832	178276	unknown	unknown
YIL061C	SNP1______	-1.06	241639	227425	mRNA splicing	U1 snRNP protein
YJL159W	HSP150____	+1.13	11208963	12718414	heat shock response	secreted glycoprotein of HSP family
YKL155C	__________	+1.07	452474	483415	unknown	unknown
YLR089C	__________	-1.34	600035	448883	unknown	unknown; similar to alanine aminotransferase
YLR459W	CDC91_____	+1.06	137878	145684	unknown	unknown; major facilitator superfamily
YMR192W	__________	+1.13	182891	206946	unknown	unknown; similar to mouse Tbc1 protein
YNL250W	RAD50_____	+1.10	122503	135180	DNA repair	DNA binding protein
YOL154W	__________	-1.07	208411	194883	unknown	unknown; similar to Sartorya fumigata Asp FII
YOR364W	__________	+1.02	120133	122977	unknown	unknown
YPR061C	__________	+1.08	142343	153258	unknown	unknown; similar to E. coli DnaJ and other DnaJ-like
YBR039W	ATP3______	+1.21	1194487	1448278	ATP synthesis	mitochondrial F1F0 ATP synthase subunit
YCL062W	__________	-1.01	216444	214783
YDL156W	__________	-1.09	111997	102605	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDR277C	MTH1______	+1.09	131038	142611	hexose transport	transcriptional repressor
YEL060C	PRB1______	+1.17	219583	257834	protein degradation	vacuolar protease B
YGR079W	__________	-1.14	567587	495924	unknown	unknown
YHR093W	AHT1______	+1.10	129770	142603	unknown	unknown
YJR125C	ENT3______	-1.24	728525	588783	endocytosis (putative)	unknown; epsin homolog
YLR273C	PIG1______	-1.05	130723	124819	glucose repression	(putative) Glc7p regulatory subunit
YMR012W	CLU1______	-1.19	1523718	1285439	protein synthesis	translation initiation factor eIF3 subunit
YNL058C	__________	+1.44	666884	961302	unknown	unknown
YOR178C	GAC1______	-1.09	184511	169733	glycogen metabolism	Glc7p regulatory subunit
YPL156C	__________	+1.16	367231	426963	unknown	unknown
YAR007C	RFA1______	+1.00	175498	176244	DNA replication	replication factor A, 69 kD subunit
YBR239C	__________	-1.14	220181	192935	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YDR108W	GSG1______	+1.04	192508	199503	meiosis	unknown
YDR477W	SNF1______	-1.14	352399	310291	glucose derepression	protein kinase
YER165W	PAB1______	-1.16	2580637	2228703	mRNA 3'-end processing	cleavage/polyadenylation factor CF IA component
YGL170C	__________	-1.12	199864	177865	unknown	unknown; similar to phosphoribulokinase precursor
YGR277C	__________	+1.03	396606	409836	unknown	unknown; similar to Ctr1p
YIL071C	__________	+1.02	206080	210367	unknown	unknown
YJL171C	__________	+1.59	245143	388606	unknown	unknown
YKL167C	MRP49_____	+1.13	315562	356893	protein synthesis	ribosomal protein, mitochondrial large subunit
YLR101C	__________	+1.31	1559772	2035714	unknown	unknown
YMR203W	TOM40_____	-1.22	763821	625486	mitochondrial protein targeting	outer membrane translocase component
YNL262W	POL2______	-1.01	117789	116722	DNA replication	polymerase epsilon catalytic subunit
YOL166C	__________	-1.09	129921	119474	unknown	unknown
YOR376W	__________	-1.04	117170	112135	unknown	unknown; similar to Na+/K+-exchanging ATPases
YPR073C	LTP1______	+1.16	645813	751914	unknown	protein phosphatase
YBR051W	__________	-1.02	106785	104625	unknown	unknown
YCLX01W	__________	+1.01	430961	434287
YDL168W	SFA1______	-1.02	710494	699511	formaldehyde metabolism	long-chain alcohol dehydrogenase
YDR289C	RTT103____	-1.06	287900	272404	transposition (putative)	unknown; similar to Spt8p
YEL072W	__________	+1.16	150179	174604	unknown	unknown
YGR091W	PRP31_____	+1.04	196505	204467	mRNA splicing	U4/U6, U5 snRNP protein
YHR105W	__________	+1.01	148030	149982	unknown	unknown; similar to Grd19p and bacterial helix-turn-helix
YJR137C	ECM17_____	+1.09	139232	151474	cell wall biogenesis	unknown
YLR285W	__________	-1.08	609525	566657	unknown	unknown
YMR024W	MRPL3_____	-1.00	297624	296599	protein synthesis	ribosomal protein, mitochondrial L3
YNL070W	TOM7______	+1.19	270204	321600	mitochondrial protein targeting	small subunit of translocase
YOR190W	SPR1______	-1.07	190785	177631	sporulation	exo-1,3-beta-glucanase
YPL168W	__________	+1.03	174021	179626	unknown	unknown
YAR029W	__________	+1.11	99243	110455	unknown	unknown; similar to subtelomerically-encoded proteins
YBR251W	MRPS5_____	+1.09	339287	370675	protein synthesis	ribosomal protein, mitochondrial S5
YDR120C	TRM1______	-1.42	574229	404284	tRNA processing	tRNA methyltransferase
YDR489W	__________	+1.07	189316	202073	unknown	unknown
YER175C	__________	+1.03	152723	158016	unknown	unknown; similar to Yhr209p
YGL182C	__________	-1.09	103450	95176	unknown	unknown
YGR289C	MAL11_____	-1.06	147068	139257	transport	alpha-glucoside permease
YJL183W	MNN11_____	-1.15	791063	687200	unknown	mannosyltransferase complex subunit
YKL179C	__________	-1.31	233527	177881	unknown	unknown; similar to kinesin and human kinesin-related
YLR113W	HOG1______	-1.15	634313	553179	signaling, high osmolarity pathway	MAPK (mitogen-activated protein kinase)
YMR215W	__________	-1.40	536652	382084	unknown	unknown; similar to Gas1p
YNL274C	__________	+1.13	177523	201239	unknown	putative alpha-ketoisocaproate reductase
YOR012W	__________	-1.07	131065	122321	unknown	unknown
YOR388C	FDH1______	-1.23	165978	135422	unknown	unknown; similar to formate dehydrogenases
YPR085C	__________	-1.09	294710	269282	unknown	unknown
YBR063C	__________	+1.00	225620	226545	unknown	unknown; similar to phosphopanthethein-binding proteins
YCR001W	__________	+1.11	102464	114185	unknown	unknown
YDL180W	__________	+1.07	294350	316162	unknown	unknown
YDR301W	CFT1______	+1.07	132157	140812	mRNA 3'-end processing	cleavage/polyadenylation factor CF II component
YER006W	__________	-1.22	1619707	1329223	unknown	unknown; similar to mouse Mmr1p protein
YGR103W	__________	-1.30	1879629	1441059	unknown	unknown
YHR117W	TOM71_____	-1.14	738517	647243	mitochondrial protein targeting	outer membrane translocase component
YJR149W	__________	-1.29	187356	144829	unknown	unknown; similar to 2-nitropropane dioxygenase
YLR296W	__________	-1.08	161228	149571	unknown	unknown
YMR035W	IMP2______	-1.04	188591	180793	protein processing	mitochondrial inner membrane protease
YNL082W	PMS1______	-1.16	209485	180390	DNA repair	MutL homolog; mismatch repair
YOR200W	__________	+1.15	313039	360332	unknown	unknown
YPL180W	__________	-1.02	128544	126460	unknown	unknown
YBL002W	HTB2______	+1.02	197271	200452	chromatin structure	histone H2B
YBR263W	SHM1______	-1.42	594704	419855	one-carbon interconversion	serine hydroxymethyltransferase
YDL002C	NHP10_____	-1.02	456648	445905	chromatin structure	non-histone protein
YDR132C	__________	-1.16	226214	194928	unknown	unknown
YDR501W	PLM2______	+1.06	272091	288569	plasmid maintenance (putative)	unknown
YFL-TYB	TY2B______	+1.05	15695157	16512232
YGL194C	HOS2______	+1.00	226682	226729	chromatin structure	putative histone deacetylase
YIL093C	__________	+1.09	268168	292003	unknown	unknown
YJL195C	__________	-1.05	123169	116809	unknown	unknown
YKL191W	DPH2______	-1.24	684790	554022	diphthamide biosynthesis	unknown
YLR125W	__________	+1.03	101789	104787	unknown	unknown
YML002W	__________	-1.08	194208	180280	unknown	unknown
YMR227C	TAF67_____	-1.05	238925	227823	transcription	TFIID 67 kD subunit
YOR024W	__________	-1.04	194085	187332	unknown	unknown
YPL002C	SNF8______	-1.01	303856	301531	glucose derepression	unknown
YPR097W	__________	-1.29	565747	437626	unknown	unknown
YBR075W	__________	-1.31	524467	400930	unknown	unknown
YCR013C	__________	+1.06	14491276	15292075	unknown	unknown
YDL192W	ARF1______	+1.05	5393558	5641781	secretion	ADP-ribosylation factor
YDR313C	PIB1______	-1.02	308052	301706	signaling	phosphatidylinositol(3)-phosphate binding
YER015W	FAA2______	-1.25	207256	166177	fatty acid metabolism	acyl-CoA synthetase
YGL002W	ERP6______	-1.04	339606	327375	membrane trafficking; secretion (putative)	unknown
YGR113W	DAM1______	+1.02	197002	200889	unknown	unknown; interacts with Duo1p and Mps1p
YHR129C	ARP1______	+1.05	273773	286095	cytoskeleton	actin-related protein
YJL002C	OST1______	-1.03	570663	555928	protein glycosylation	oligosaccharyltransferase complex subunit
YKL002W	__________	+1.36	605313	821876	unknown	unknown
YLL002W	REM50_____	+1.11	162567	180487	diepoxybutane and mitomycin C resistance	unknown
YLR308W	CDA2______	+1.02	98080	100373	sporulation	chitin deacetylase
YMR046C	__________	-1.26	2807532	2222700	unknown	unknown
YNL094W	__________	+1.11	313489	347735	unknown	unknown
YOL002C	__________	+1.12	530610	595493	unknown	unknown
YOR212W	STE4______	-1.14	575256	506345	signaling, pheromone pathway	beta subunit of G protein
YPL191C	__________	-1.03	150629	146484	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YAR052C	__________	-1.23	168041	136649
YBL012C	__________	-1.11	128236	115870	unknown	unknown
YBR275C	RIF1______	-1.17	216688	185162	silencing	RAP1-interacting protein
YDL014W	NOP1______	-1.72	4373016	2547312	rRNA processing, 35S	fibrillarin homolog
YDR144C	MKC7______	-1.52	671732	441508	protein degradation	periplasmic aspartyl protease
YDR513W	TTR1______	+1.35	661580	892035	electron carrier	glutaredoxin
YFL011W	HXT10_____	-1.15	253029	220934	transport	hexose permease
YGL206C	CHC1______	+1.14	94640	108122	endocytosis and secretion	clathrin heavy chain
YHL010C	__________	+1.12	99662	111255	unknown	unknown
YIL104C	__________	+1.43	2274591	3249347	unknown	unknown
YJL207C	__________	+1.17	94789	110594	unknown	major facilitator superfamily
YKL203C	TOR2______	+1.13	96966	109898	signaling, cell cycle, meiosis and actin cytoskeleton organization	phosphatidylinositol 3-kinase
YLR137W	__________	+1.20	162060	194491	unknown	unknown
YMR239C	RNT1______	-1.33	241955	181510	rRNA processing	ribonuclease III
YNL296W	__________	-1.10	107839	98370	unknown	unknown
YOR036W	PEP12_____	+1.34	340987	456816	vacuolar protein targeting	t-SNARE
YPL014W	__________	+1.54	339449	522422	unknown	unknown
YPR109W	__________	+1.03	287373	297098	unknown	unknown
YBR086C	IST2______	-1.11	503068	453570	salt tolerance (putative)	unknown; similar to calcium and sodium channel proteins
YCR024C	__________	-1.01	150146	149385	protein synthesis	tRNA synthetase, mitochondrial, asparaginyl
YDL204W	__________	+1.10	103684	114212	unknown	unknown
YDR323C	PEP7______	-1.16	161530	138721	vacuolar protein targeting	vacuolar segregation protein
YER026C	CHO1______	-1.03	683841	662396	phospholipid metabolism	phosphatidylserine synthase
YGL014W	__________	-1.19	562445	471811	aging	Sir3p and Sir4p localization
YGR125W	__________	-1.00	308509	308241	unknown	unknown; sulfate permease family
YJL014W	CCT3______	-1.20	1139682	952229	protein folding	cytoplasmic chaperonin complex
YKL013C	ARC19_____	+1.18	669179	792712	cytoskeleton	cortical actin patch integrity
YLL014W	__________	+1.43	257718	367498	unknown	unknown
YLR319C	BUD6______	+1.04	201647	208874	bud site selection, bipolar	actin-interacting protein
YMR056C	AAC1______	-1.03	170945	165659	transport	mitochondrial ADP/ATP translocator
YNL106C	INP52_____	-1.06	1191588	1127115	endocytosis (putative)	inositol polyphosphate 5-phosphatase
YOL014W	__________	-1.33	1049013	790764	unknown	unknown
YOR224C	RPB8______	-1.09	1661503	1518238	transcription	shared subunit of RNA polymerase I,II, and III
YPL203W	PKA3______	-1.01	298379	296149	signaling, nutrient control of cell growth	cAMP-dependent protein kinase catalytic subunit
YAR074C	__________	-1.78	1097292	617522
YBL024W	NCL1______	-1.36	732048	536967	unknown	unknown; similar to human proliferating cell nucleolar antigen
YBR287W	__________	+1.27	308917	392485	unknown	unknown
YDL026W	__________	-1.19	115479	96723	unknown	unknown
YDR156W	RPA14_____	-1.30	385991	296256	transcription	RNA polymerase I subunit A14
YDR525W	__________	+1.01	107438	108527	unknown	unknown
YFL020C	PAU5______	+1.08	247292	265924	unknown	unknown; similar to members of the Srp1p/Tip1p family
YGL218W	__________	-1.18	151771	128772	unknown	unknown
YHL022C	SPO11_____	+1.27	119694	152394	meiosis, recombination	ds break formation complex catalytic subunit
YIL116W	HIS5______	+1.13	424166	478611	histidine biosynthesis	histidinol-phosphate aminotransferase
YJL219W	HXT9______	+1.17	163539	190673	transport	hexose permease
YKL215C	__________	+1.20	208773	250695	unknown	unknown; similar to Pseudomonas hydantoinases hyuA-hyuB
YLR149C	__________	+1.15	115286	132389	unknown	unknown
YML023C	__________	+1.00	180971	181449	unknown	unknown
YNL308C	KRI1______	-1.31	864547	657507	unknown	unknown; similar to Mgm1p
YOR048C	RAT1______	-1.36	843079	618747	transcription	exonuclease II
YPL026C	SKS1______	-1.03	286754	279331	glucose transport (putative)	protein kinase
YPR121W	THI22_____	-1.05	170179	162163	thaimine metabolism	unknown
YBR097W	VPS15_____	-1.15	105865	92117	vacuolar protein targeting	ser/thr protein kinase
YCR034W	FEN1______	+1.01	737391	743792	cell wall biogenesis	beta-1,3-glucan synthase subunit
YDL216C	__________	+1.04	148464	154350	unknown	unknown
YDR335W	MSN5______	-1.07	226270	211331	signaling	pheromone pathway
YER038C	__________	+1.20	144160	173647	unknown	unknown
YGL026C	TRP5______	+1.06	785041	833643	tryptophan biosynthesis	tryptophan synthase
YGR137W	__________	+1.59	850019	1349357	unknown	unknown; similar to tomato extensin PIR:S14983
YHR150W	__________	+1.25	149712	187472	unknown	unknown
YJL026W	RNR2______	+1.01	799410	808344	DNA replication	ribonucleotide reductase
YKL025C	PAN3______	+1.10	318032	350428	mRNA processing	Pab1p-dependent poly(A) ribonuclease subunit
YLL026W	HSP104____	+1.22	269515	328739	heat shock response /thermotolerance	heat shock protein
YLR331C	__________	-1.05	140936	134571	unknown	unknown
YMR068W	__________	+1.11	157269	174852	unknown	unknown; similar to mouse I kappa B gamma and p70
YNL118C	DCP2______	+1.02	268699	275002	respiration (putative)	unknown; suppresses pet mutant
YOL026C	__________	+1.23	418698	513081	unknown	unknown
YOR236W	DFR1______	+1.04	560586	585615	folate biosynthesis	dihydrofolate reductase
YPL215W	CBP3______	+1.16	362495	421816	respiration	cytochrome-c reductase assembly
YER187W	__________	+1.03	148372	153358	unknown	unknown; similar to killer toxin Khs1p
YBL036C	__________	+1.08	629578	682101	unknown	unknown; similar to Pseudomonas aeroginosa twitching motility protein
YBR299W	MAL32_____	-1.06	154643	146484	maltose metabolism	alpha-glucosidase
YDL038C	__________	-1.70	299829	176611	unknown	unknown
YDR168W	CDC37_____	+1.03	552660	571625	cell cycle	chaperone
YDR537C	__________	-1.18	202634	171049	unknown	unknown
YFL031W	HAC1______	-1.20	125547	104604	unfolded protein response	transcription factor
YGL229C	SAP4______	-1.04	190030	182775	cell cycle	Sit4p-associated protein
YHL033C	RPL8A_____	-1.40	11467811	8207342	protein synthesis	ribosomal protein L8A
YIL128W	MET18_____	-1.19	267694	225025	transcription and DNA repair	regulator of TFIIH
YJR007W	SUI2______	-1.17	1699787	1450105	protein synthesis	translation initiation factor eIF-2 alpha subunit
YKR002W	PAP1______	-1.15	393575	342440	mRNA polyadenylation	poly(A) polymerase
YLR159W	__________	-1.04	107908	103343	unknown	unknown
YMR263W	__________	+1.15	336239	385072	unknown	unknown
YNL320W	__________	+1.17	316305	369439	unknown	unknown; similar to S. pombe bem1/bud5 suppressor (Bem46+)
YOR060C	__________	-1.01	144694	142757	unknown	unknown
YPL038W	MET31_____	-1.08	304910	282443	sulfur amino acid metbolism	transcription factor
YPR133C	__________	-1.03	604071	585500	unknown	unknown
YBR109C	CMD1______	+1.23	1207501	1490709	signaling	calmodulin
YCR046C	IMG1______	-1.00	399603	398624	protein synthesis	ribosomal protein, mitochondrial
YDL228C	__________	-1.07	103173	96365	unknown	unknown; similar to Achlya klebsiana glutamate
YDR347W	MRP1______	-1.02	511686	499895	protein synthesis	ribosomal protein, mitochondrial small subunit
YER047C	SAP1______	-1.13	198956	175580	mating type switching	AAA family protein
YGL038C	OCH1______	-1.10	391609	355883	protein glycosylation	membrane-bound mannosyltransferase
YGR149W	__________	+1.32	193334	255436	unknown	unknown; similar to hypothetical protein A-288
YHR162W	__________	+1.27	3054010	3887182	unknown	unknown
YJL038C	__________	+1.05	172270	181516	unknown	unknown
YKL036C	__________	-1.08	192592	178966	unknown	unknown
YLL038C	ENT4______	+1.13	126243	142764	endocytosis (putative)	unknown; epsin homolog
YLR343W	__________	+1.13	168590	191038	unknown	unknown; similar to Gas1p
YNL130C	CPT1______	+1.05	533404	558849	phospholipid metabolism	diacylglycerol cholinephosphotransferase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOL038W	PRE6______	+1.09	1934342	2107182	protein degradation	20S proteasome subunit (alpha4)
YOR248W	__________	+1.40	3192960	4462050	unknown	unknown
YPL227C	ALG5______	+1.12	869344	973947	protein glycosylation	UDP-glucose:dolichyl-phosphate glucosyltransferase
YBL048W	__________	-1.03	92889	90226	unknown	unknown
YDL050C	__________	-1.20	708721	591100	unknown	unknown
YDR178W	SDH4______	+1.44	307852	442397	TCA cycle, oxidative phosphorylation	succinate dehydrogenase anchor subunit
YFL041W	FET5______	-1.04	258223	248234	transport	iron transporter, multicopper oxidase
YGL241W	KAP114____	+1.01	223776	226977	nuclear protein targeting	karyopherin
YHL045W	__________	-1.02	131212	128323	unknown	unknown
YIL140W	SRO4______	+1.01	290371	294275	bud site selection, axial	unknown; plasma membrane protein
YJR018W	__________	-1.54	321189	208255	unknown	unknown
YKR014C	YPT52_____	+1.11	788257	876457	endocytosis	GTP-binding protein, rab family
YLR171W	__________	-1.01	299759	296642	unknown	unknown
YMR275C	BUL1______	-1.11	198784	178425	protein degradation, ubiquitin-mediated	unknown; binds Rsp5p ubiquitin ligase
YNL332W	THI12_____	-1.07	166224	154906	pyrimidine biosynthesis	unknown
YOR072W	__________	+1.01	117714	118719	unknown	unknown
YPL050C	MNN9______	-1.14	680137	594668	protein glycosylation	mannosyltransferase complex subunit
YPR143W	__________	-1.07	709059	664112	unknown	unknown
YBR120C	CBP6______	+1.19	172344	204409	protein synthesis, COB	translation activator of COB mRNA
YCR058C	__________	-1.14	91421	79991
YDL240W	LRG1______	-1.34	183391	136800	sporulation	GTPase-activating protein of the rho/rac family
YDR359C	VID21_____	-1.08	517199	477312	vacuolar protein targeting (putative)	unknown
YER058W	PET117____	+1.06	156628	166666	respiration	cytochrome c oxidase assembly factor
YGL050W	__________	-1.01	168869	166702	unknown	unknown
YGR161C	__________	-1.95	572018	292646	unknown	unknown
YHR174W	ENO2______	+1.19	15819104	18829887	glycolysis	enolase II
YJL051W	__________	-1.26	471203	373738	unknown	unknown
YKL048C	ELM1______	-1.65	691768	419110	pseudohyphal growth	protein kinase
YLL050C	COF1______	-1.23	326442	266374	cytoskeleton	cofilin
YLR355C	ILV5______	-1.78	5021155	2816424	isoleucine and valine biosynthesis	ketol-acid reductoisomerase
YMR090W	__________	-1.23	235619	190933	unknown	unknown; similar to malate dehydrogenases
YNL142W	MEP2______	-1.13	231084	203985	transport	ammonia permease
YOL050C	__________	+1.03	325837	334661	unknown	unknown
YOR260W	GCD1______	-1.42	763919	536876	protein synthesis	translation initiation factor eIF2b gamma subunit
YPL239W	YAR1______	-1.09	1215795	1119523	unknown	unknown
YJR161C	COS5______	+1.47	745547	1093382	unknown	unknown; similar to subtelomerically-encoded proteins
YBL060W	__________	+1.02	216911	221215	unknown	unknown
YDL062W	__________	-1.43	125264	87379	unknown	unknown
YDR189W	SLY1______	-1.03	557857	540845	secretion	SNARE docking complex subunit
YFL053W	DAK2______	+1.01	120976	122243	carbohydrate metabolism; stress response	dihydroxyacetone kinase
YGL253W	HXK2______	-1.04	4491416	4330070	glycolysis	hexokinase II
YHR005C	GPA1______	-1.40	1524469	1085451	signaling, pheromone pathway	alpha subunit of G protein coupled to mating factor
YIL152W	__________	-1.18	562438	477260	unknown	unknown
YJR029W	__________	+1.20	15847924	19016502	unknown	unknown; similar to malate dehydrogenase
YKR026C	GCN3______	-1.49	2133405	1435251	protein synthesis	translation initiation factor EIF2B
YLR183C	__________	-1.57	749307	477299	unknown	unknown
YML054C	CYB2______	+1.10	181936	199683	lactate utilization	cytochrome b2
YMR287C	MSU1______	-1.17	172792	147624	mitochondrial biogenesis	component of 3'-5' exonuclease complex
YNR005C	__________	-1.26	136663	108843	unknown	unknown
YOR084W	__________	-1.04	257325	247250	unknown	unknown
YPL060W	__________	-1.03	207354	200473	unknown	unknown; similar to Mrs2p
YPR155C	NCA2______	-1.05	188633	180058	ATP synthesis	regulates Atp6p and Atp8p synthesis
YBR132C	AGP2______	-1.01	129228	128198	transport	general amino acid permease
YCR069W	SCC3______	-1.14	247503	217486	protein folding	peptidyl-prolyl cis-trans isomerase
YDR004W	RAD57_____	+1.05	230167	242344	DNA repair and recombination	RecA homolog
YDR369C	XRS2______	-1.00	150621	150284	DNA repair and recombinations	required for ds break repair
YGL062W	PYC1______	-1.29	320278	248182	TCA cycle	pyruvate carboxylase 1
YGR169C	__________	-1.25	322313	256972	unknown	unknown
YHR186C	__________	-1.48	467194	314758	unknown	unknown; similar to Cdc39p, has WD (WD-40) domain
YJL063C	MRPL8_____	-1.15	583323	509029	protein synthesis	ribosomal protein, mitochondrial L8
YKL060C	FBA1______	+1.19	15899878	18871921	glycolysis	aldolase
YLL062C	MHT1______	-1.39	542993	389651	sulfur amino acid metabolism	S-methylmethionine:homocysteine S-methyltransferase
YLR367W	RPS22B____	-1.05	7704392	7309661	protein synthesis	ribosomal protein S22B
YMR102C	__________	-1.11	159504	143919	unknown	unknown
YNL154C	YCK2______	-1.19	1009372	849955	unknown	protein kinase
YOL060C	AMI3______	-1.19	190804	160950	mitochondrial morphology (putative)	unknown
YOR272W	YTM1______	-1.42	718725	506877	cytoskeleton (putative)	microtubule-associated protein
YPL250C	ICY2______	+1.06	143567	152325	cytoskeleton (putative)	unknown
YMR317W	__________	-1.10	110923	100970	unknown	unknown
YBL072C	RPS8A_____	+1.20	15812252	18965107	protein synthesis	ribosomal protein S8
YDL074C	__________	-1.08	328293	304354	unknown	unknown
YDR201W	SPC19_____	-1.20	509522	425038	cytoskeleton	spindle pole body component
YFL065C	__________	-1.16	298111	257144	unknown	unknown; similar to other subtelomerically-encoded proteins
YGR002C	__________	-1.08	227404	210877	unknown	unknown; similar to Drosophila melanogaster transcription
YHR016C	YSC84_____	+1.11	273488	304362	unknown	unknown; similar to hypothetical protein YFR024c-a
YIL163C	__________	-1.00	164177	163559	unknown	unknown
YJR041C	__________	-1.16	183807	159093	unknown	unknown; similar to Podospora anserina NADH dehydrogenase
YKR038C	__________	+1.03	538929	557404	unknown	unknown; similar to Qri7p and Pasteurella haemolytica
YLR195C	NMT1______	-1.24	323187	261051	protein processing	N-myristoyltransferase
YML065W	ORC1______	-1.22	335558	274554	DNA replication	origin recognition complex 104 kD subunit
YMR297W	PRC1______	+1.00	682583	685963	sporulation	carboxypeptidase Y
YNR017W	MAS6______	-1.27	846715	667573	mitochondrial protein targeting	inner membrane translocase component
YOR096W	RPS7A_____	+1.01	11552644	11625561	protein synthesis	ribosomal protein S7A
YPL072W	UBP16_____	+1.00	279893	280992	protein degradation, ubiquitin-mediated	putative deubiquitinating enzyme
YPR163C	TIF3______	-1.41	4119065	2921683	protein synthesis	translation initiation factor eIF4B
YBR144C	__________	-1.04	96169	92317	unknown	unknown
YCR082W	__________	+1.23	437425	539859	unknown	unknown
YDR016C	DAD1______	+1.20	298079	356416	unknown	unknown; localizes to spindles and spindle pole bodies
YDR381W	YRA1______	+1.15	1250839	1444450	mRNA processing	RNA annealing protein
YER078C	__________	-1.09	239072	218770	unknown	unknown; similar to E. coli X-Pro aminopeptidase II
YGL074C	__________	-1.00	99574	99516	unknown	unknown
YGR181W	TIM13_____	+1.06	624943	661232	mitochondrial protein targeting	inner membrane translocase subunit
YHR198C	__________	-1.02	264504	258429	unknown	unknown; similar to Yhr199p
YJL075C	__________	-1.03	573821	559500	unknown	unknown
YKL072W	STB6______	-1.06	205507	193515	unknown	binds Sin3p
YLR007W	__________	-1.02	546276	533940	unknown	unknown
YLR379W	__________	-1.59	163942	102913	unknown	unknown
YMR114C	__________	+1.11	206505	228487	unknown	unknown
YNL166C	BNI5______	-1.03	546695	530760	unknown	unknown; localizes to mother-bud neck
YOL072W	__________	-1.15	244897	212944	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOR284W	__________	-1.17	193488	165235	unknown	unknown
YPL260W	__________	-1.08	540564	501484	unknown	unknown
YBL084C	CDC27_____	+1.12	93954	104865	cell cycle	anaphase-promoting complex subunit
YDL086W	__________	-1.04	748690	722195	unknown	unknown
YFR009W	GCN20_____	+1.08	101074	108665	protein synthesis	activator of Gcn2p kinase; ABC superfamily
YGR014W	MSB2______	-1.20	540836	451738	bud emergence	unknown
YHR027C	RPN1______	-1.16	583755	503310	protein degradation	26S proteasome regulatory subunit
YIL174W	__________	-1.04	144380	139365	unknown	unknown; similar to Yir040p
YJR053W	BFA1______	-1.24	147336	118555	unknown	unknown
YKR050W	TRK2______	-1.10	113026	102869	transport	potassium permease
YLR207W	HRD3______	-1.08	192100	177969	protein degradation	HMG-CoA reductase degradation
YML077W	BET5______	+1.08	446283	484173	secretion (putative)	unknown; suppresses bet3 mutation
YMR307W	GAS1______	-1.34	3914546	2917271	unknown	cell surface glycoprotein
YNR029C	__________	-1.07	437733	409914	unknown	unknown; similar to Rhodococcus sp. nitrile hydratase
YOR108W	__________	-1.72	757380	439493	unknown	unknown; similar to Leu4p
YPL084W	BRO1______	-1.19	442302	370214	unknown	unknown
YPR175W	DPB2______	-1.06	177412	166914	DNA replication	polymerase epsilon 80 kDa subunit
YBR156C	SLI15_____	-1.04	297462	286106	mitosis, chromosome segregation	unknown
YCR093W	CDC39_____	-1.09	363475	334652	transcription	general negative regulator
YDR028C	REG1______	-1.12	246394	219947	glucose repression	protein phosphatase regulator
YDR393W	SHE9______	-1.13	291150	257501	unknown	unknown
YER089C	PTC2______	-1.04	702733	678827	unknown	protein phosphatase
YGL086W	MAD1______	-1.12	656341	585980	cell cycle	spindle checkpoint complex subunit
YGR193C	PDX1______	-1.16	676443	581296	glycolysis	pyruvate dehydrogenase
YHR210C	__________	+1.02	178579	182451	unknown	unknown; similar to Gal10p, has strong similarity to
YJL087C	TRL1______	-1.19	327669	276141	tRNA splicing	tRNA ligase
YKL084W	__________	+1.01	285130	287878	unknown	unknown
YLR019W	PSR2______	-1.30	401123	308889	salt tolerance (putative)	phosphatase
YLR390W	SSR1______	+1.77	1439671	2548509	unknown	secretory stress response
YMR125W	STO1______	-1.15	235371	204505	glycolysis	large subunit of the nuclear CAP-binding protein complex
YNL178W	RPS3______	+1.14	14107010	16114414	protein synthesis	ribosomal protein S3
YOL084W	__________	-1.42	204101	144238	unknown	major facilitator superfamily
YOR296W	__________	-1.03	140755	136273	unknown	unknown; may be involved in bud site selection (YPD)
YPL272C	__________	-1.09	174445	160420	unknown	unknown
YAL003W	EFB1______	-1.15	8408258	7289362	protein synthesis	translation elongation factor EF1-beta
YBR168W	__________	-1.19	239975	202088	unknown	unknown
YCR105W	__________	-1.26	202465	160920	unknown	unknown; similar to bovine alcohol dehydrogenase
YDR039C	ENA2______	-1.32	264572	200311	transport	plasma membrane ATPase
YDR406W	PDR15_____	-1.47	314429	214147	drug resistance	putative transporter
YER101C	AST2______	-1.35	272653	201930	plasma membrane protein targeting	targets plasma membrane ATPase
YGL099W	__________	-1.16	186627	160941	unknown	unknown; similar to human possible GTP-binding protein HSR1
YGR206W	__________	+1.20	206490	248350	unknown	unknown
YIL003W	__________	-1.23	393967	320703	unknown	unknown; similar to E. coli MRP protein
YJL100W	__________	+1.23	178338	220058	unknown	unknown
YKL097C	__________	+1.21	92039	111170	unknown	unknown
YLR032W	RAD5______	+1.12	85466	95422	DNA repair	DNA helicase
YLR404W	__________	+1.15	185428	213865	unknown	unknown
YMR137C	PSO2______	-1.05	135743	129489	DNA repair	required for interstrand crosslink repair
YNL191W	__________	-1.03	199801	193477	unknown	unknown
YOL097C	WRS1______	-1.37	1668358	1214089	protein synthesis	tRNA ligase, tryptophan
YOR307C	SLY41_____	-1.17	391063	333724	secretion	unknown; suppresses ypt1 null
YPR002W	PDH1______	-1.05	127110	121501	proionate metabolism (putative)	unknown; prpD homolog
YBL097W	BRN1______	-1.12	139592	124408	chromosome maintenance	unknown; homolog of human BRRN1
YCL002C	__________	-1.08	162809	150600	unknown	unknown
YDL099W	__________	-1.03	571161	554819	unknown	unknown
YDR222W	__________	-1.05	270050	256201	unknown	unknown
YEL003W	GIM4______	+1.26	511967	642526	protein folding	chaperone; tubulin folding
YFR022W	__________	-1.03	136334	131732	unknown	unknown
YGR027C	RPS25A____	+1.13	15487803	17478430	protein synthesis	ribosomal protein S25A
YHR039C	__________	-1.01	310563	308546	unknown	unknown; similar to aldehyde dehydrogenases
YIR010W	__________	+1.07	393080	421606	unknown	unknown
YJR066W	TOR1______	+1.09	1003820	1097070	signaling, cell cycle and meiosis	phosphatidylinositol 3-kinase
YKR063C	LAS1______	-1.00	442134	440825	morphogenesis, cytoskeletal assembly, bud formation	(putative) gene expression
YLR220W	CCC1______	-1.12	447685	399045	ion homeostasis, Ca2+ and Mn2+	transmembrane transporter, putative
YML090W	__________	-1.08	112442	104549	unknown	unknown
YNL003C	PET8______	+1.30	373768	485324	mitochondrial protein targeting	mitochondrial carrier family
YNR042W	__________	-1.16	130736	112476	unknown	unknown
YOR121C	__________	+1.08	277674	298781	unknown	unknown
YPL097W	MSY1______	-1.15	235695	205755	protein synthesis	tRNA synthetase, mitochondrial, tyrosyl
YPR188C	MLC2______	+1.16	563017	651985	cytoskeleton	myosin light chain
YAL016W	TPD3______	-1.10	571854	521335	tRNA biosynthesis, cytokinesis, ceramide-mediated signaling	protein phosphatase (PP2A regulatory subunit)
YBR180W	DTR1______	-1.13	151408	134136	sporulation	dityrosine transporter
YCRX10W	__________	+1.08	280491	301588
YDR051C	__________	-1.12	333262	297244	unknown	unknown
YDR418W	RPL12B____	-1.23	13649917	11093409	protein synthesis	ribosomal protein L12B
YER113C	__________	-1.16	438729	378269	unknown	unknown; similar to Emp70p
YGL111W	__________	-1.38	833292	605121	unknown	unknown
YGR218W	CRM1______	-1.08	398802	369494	nuclear protein targeting	nuclear export factor
YIL014W	MNT3______	-1.02	297970	292295	protein glycosylation	mannosyltransferase
YJL112W	MDV1______	-1.01	288697	284626	unknown	unknown
YKL108W	SLD2______	+1.09	189594	207438	DNA replication	unknown; interacts with Dpb11p
YLR042C	__________	+1.29	206790	267270	unknown	unknown
YLR414C	__________	+2.16	852547	1840079	unknown	unknown
YMR149W	SWP1______	-1.04	928488	894681	protein glycosylation	oligosaccharyltransferase complex subunit
YNL203C	__________	-1.07	140585	130882	unknown	unknown; similar to Bacillus subtilis
YOL107W	__________	-1.00	210616	209697	unknown	unknown; similar to Rnh70p and Pan2p
YOR319W	HSH49_____	-1.08	262784	244024	mRNA splicing	U2 snRNP protein; human SAP145 homolog
YPR014C	__________	-1.05	124653	118281	unknown	unknown
YBL107C	__________	+1.02	368381	376246	unknown	unknown
YCL014W	BUD3______	-1.08	110794	102423	cell polarity	bud site selection
YDL111C	RRP42_____	-1.20	704454	587102	rRNA processing	exoribonuclease
YDR234W	LYS4______	-1.33	224762	169002	lysine biosynthesis	homoaconitase
YEL015W	__________	-1.41	293866	208378	unknown	unknown
YGR037C	ACB1______	+1.13	998552	1131070	fatty acid metabolism	acyl-CoA ester transporter
YHR050W	SMF2______	+1.12	317677	355164	transport	(putative) manganese transporter
YJR078W	__________	+1.27	106914	136236	unknown	unknown; similar to indoleamine 2,3-dioxygenase
YKR075C	__________	+1.22	216657	263524	unknown	unknown; similar to Reg1p
YLR230W	__________	-1.14	292582	256518	unknown	unknown
YML100W	TSL1______	+1.27	231237	293667	trehalose metabolism	trehalose-6-phosphate synthase/phosphatase complex regulatory subunit
YNL015W	PBI2______	+1.95	268189	524028	unknown	protease inhibitor

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNR054C	__________	-1.19	885861	742708	unknown	unknown
YOR133W	EFT1______	-1.21	6427040	5301421	protein synthesis	translation elongation factor eEF2
YPL109C	__________	-1.04	172957	166530	unknown	unknown
YPR200C	ARR2______	-1.12	175455	156659	arsenic resistance	unknown
YAL028A	__________	-1.09	98416	89916
YBR192W	RIM2______	-1.08	103489	96009	transport	mitochondrial carrier family
YDR063W	__________	+1.13	459076	519842	unknown	unknown
YDR430C	__________	-1.18	154333	130896	unknown	unknown; similar to class I family of aminoacyl-tRNA
YER124C	__________	-1.05	283254	270782	unknown	unknown
YGL123W	RPS2______	-1.17	5651491	4816195	protein synthesis	ribosomal protein S2
YGR230W	BNS1______	+1.42	236460	336532	unknown	unknown; similar to Spo12p; bypasses spo12/spo12 deletion
YIL026C	IRR1______	+1.00	187012	187412	unknown	colony morphology
YJL124C	LSM1______	+1.02	770009	785657	mRNA splicing (putative)	similar to snRNA-associated protein
YKL120W	OAC1______	-1.43	460171	321098	transport	oxaloacetate carrier
YLR054C	__________	+1.25	95837	119839	unknown	unknown
YMR159C	APG16_____	-1.05	129865	124245	autophagy	unknown; interacts with Apg5p and Apg12p; similar to human Sin3 complex component SAP1
YNL215W	__________	-1.08	453414	420066	unknown	unknown
YOL119C	__________	-1.24	211699	170457	unknown	unknown; similar to mammalian monocarboxylate
YOR331C	__________	-1.09	1862710	1707280	unknown	unknown
YPR026W	ATH1______	+1.02	114453	116180	trehalose metabolism	vacuolar acid trehalase
YBR006W	UGA5______	+1.05	158403	165596	GABA metabolism	succinate semialdehyde dehydrogenase
YCL027W	FUS1______	-1.16	226899	195592	mating; cell fusion	SH3 domain protein
YDL123W	__________	-1.11	226522	204799	unknown	unknown
YEL026W	SNU13_____	+1.04	3683575	3843222	mRNA splicing (putative)	U4/U6.U5 snRNP protein
YFR043C	__________	+1.20	299435	359106	unknown	unknown
YGR044C	RME1______	+1.26	306560	386369	meiosis	transcription factor
YHR061C	GIC1______	+1.08	214257	231168	bud emergence	binds Cdc42p
YIR031C	DAL7______	+1.05	175183	183919	allantoin utilization	malate synthase
YJR091C	JSN1______	+1.00	157752	158256	mitosis (putative)	unknown; suppresses tub2-150
YKR087C	__________	+1.13	414548	468720	unknown	unknown; similar to neutral zinc metallopeptidases
YLR242C	ARV1______	+1.13	217367	245833	unknown	unknown; similar to C.elegans R05H5.5 protein and Nup120p
YML111W	BUL2______	-1.00	160670	160011	protein degradation, ubiquitin-mediated (putative)	unknown; similar to Bul1p
YNL027W	CRZ1______	+1.11	1555184	1734007	(calcineurin) signaling	calcineurin-responsive transcription factor
YNR066C	__________	+1.04	126985	131950	unknown	unknown; similar to Pep1p
YOR143C	THI80_____	+1.02	353528	359694	thiamine metabolism	thiamine pyrophosphokinase
YPL121C	MEI5______	+1.01	135883	137192	meiosis, synapsis and recombination	unknown
YAL037W	__________	-1.11	110078	98969	unknown	unknown
YBR204C	__________	+1.04	134385	139801	unknown	unknown; similar to peroxisomal serine-active lipase
YDR075W	PPH3______	-1.04	283945	274037	cell cycle	protein phosphatase 2A
YDR442W	__________	-1.18	128493	109043	unknown	unknown
YER136W	GDI1______	+1.10	626825	689593	secretion	regulatory; GDP dissociation inhibitor
YGL135W	RPL1B_____	+1.01	14346248	14466736	protein synthesis	ribosomal protein L1B
YGR242W	__________	-1.11	215690	194313	unknown	unknown
YIL038C	NOT3______	-1.08	338545	312110	transcription	general repressor
YJL136C	RPS21B____	+1.15	8156294	9345352	protein synthesis	ribosomal protein S21B
YKL132C	RMA1______	-1.15	238594	207607	unknown; mating (putative)	unknown; similar to folylpolyglutamate synthase
YLR066W	SPC3______	+1.21	654298	788991	secretion	signal peptidase subunit
YLR436C	ECM30_____	-1.05	798557	759652	cell wall biogenesis	unknown
YMR171C	__________	-1.09	306046	281030	unknown	unknown
YNL227C	__________	-1.03	220516	213461	unknown	unknown; similar to E. coli DnaJ and other DnaJ-like
YOL131W	__________	+1.03	101193	104429	unknown	unknown
YOR343C	__________	+1.00	113409	113498	unknown	unknown
YPR038W	__________	-1.33	277837	209130	unknown	unknown
YBR016W	__________	-1.21	372891	307390	unknown	unknown
YCL039W	__________	-1.11	101849	91853	unknown	unknown
YDL133W	__________	-1.18	301945	256026	unknown	unknown
YDR258C	HSP78_____	+1.16	228140	265500	protein folding	mitochondrial
YEL038W	UTR4______	-1.08	417527	385539	unknown	unknown
YFR055W	__________	-1.80	505997	280858	unknown	unknown; similar to E. coli cystathionine beta
YGR056W	RSC1______	-1.21	181786	150040	chromatin structure	chromatin remodeling complex subunit
YHR071W	PCL5______	+1.31	413646	541322	cell cycle	cyclin (Pho85p)
YIR043C	__________	+1.54	816084	1260212	unknown	unknown
YJR102C	__________	+1.07	151298	161253	unknown	unknown
YKR099W	BAS1______	-1.10	178756	162451	histidine, adenine biosynthesis	transcription factor
YLR254C	__________	+1.14	282324	321750	unknown	unknown
YML122C	__________	-1.12	159123	141445	unknown	unknown
YNL037C	IDH1______	+1.26	358263	449727	TCA cycle	isocitrate dehydrogenase
YOR155C	__________	-1.02	283725	277927	unknown	unknown
YPL133C	__________	-1.09	154808	141915	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YAL048C	__________	-1.22	115052	94654	secretion (putative)	unknown; similar to Ras1p, Ras2p, and other GTP-binding proteins of the RAS superfamily
YBR216C	__________	-1.13	171479	151139	unknown	unknown
YDR087C	RRP1______	-1.20	933885	777657	rRNA processing	unknown
YDR454C	GUK1______	+1.03	2064971	2117450	guanine nucleotide metabolism	guanylate kinase
YGL147C	RPL9A_____	+1.20	15727091	18837403	protein synthesis	ribosomal protein L9A
YGR254W	ENO1______	+1.21	15784253	19032651	glycolysis	enolase I
YIL050W	PCL7______	+1.18	581014	683292	cell cycle	cyclin
YJL148W	RPA34_____	-1.21	1138561	940346	transcription	RNA polymerase I subunit
YKL144C	RPC25_____	-1.43	851664	594915	transcription	RNA polymerase III 25 kD subunit
YLR078C	BOS1______	+1.08	575794	621588	secretion	ER-to-Golgi v-SNARE
YLR448W	RPL6B_____	+1.00	15362342	15437508	protein synthesis	ribosomal protein L6b
YMR181C	__________	+1.35	272786	367924	unknown	unknown
YNL239W	LAP3______	-1.25	369969	295388	protein degradation	aminopeptidase of cysteine protease family
YOL143C	RIB4______	+1.37	1647385	2264288	riboflavin biosynthesis	6,7-dimethyl-8-ribityllumazine synthase
YOR353C	__________	-1.01	338434	334803	unknown	unknown; similar to adenylate cyclases
YPR050C	__________	+1.27	451396	574814	unknown	unknown
YBR028C	__________	-1.02	295642	289471	unknown	unknown; similar to Ypk2p/Ykr2p and Ypk1p
YCL051W	LRE1______	-1.09	208793	191063	laminarase resistance	unknown
YDL145C	COP1______	-1.29	1147725	886453	secretion	vesicle coat component
YDR266C	__________	-1.20	419775	350703	unknown	unknown
YEL050C	RML2______	-1.15	336373	293427	protein synthesis	ribosomal protein, mitochondrial L2
YGR068C	__________	-1.15	133930	116049	unknown	unknown; similar to Rod1p
YHR082C	KSP1______	-1.15	212966	185592	unknown	protein kinase
YJR114W	__________	-1.40	221373	158145	unknown	unknown
YMR001C	CDC5______	-1.13	282002	250315	cell cycle	G2/M protein kinase
YNL049C	SFB2______	-1.14	200841	175919	unknown	unknown; similar to Sec24p; binds Sed3p and Sec23p
YOR167C	RPS28A____	+1.10	10706063	11770791	protein synthesis	ribosomal protein S28A
YPL145C	KES1______	-1.23	880119	716764	sterol metabolism	unknown
YAL062W	GDH3______	-1.36	174305	127888	glutamate biosynthesis	NADP-glutamate dehydrogenase
YBR228W	__________	-1.02	185359	181188	unknown	unknown
YDR466W	__________	-1.05	127016	120832	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YER156C	__________	-1.35	1458607	1083693	unknown	unknown
YGL159W	__________	-1.01	248753	246071	unknown	unknown
YGR266W	__________	-1.31	399715	305773	unknown	unknown
YIL062C	ARC15_____	+1.19	1061994	1260297	cytoskeleton	cortical actin patch integrity
YJL160C	__________	+1.08	137538	148117	unknown	unknown; similar to members of the Pir1p/Hsp150p/Pir3p
YKL156W	RPS27A____	-1.16	6514606	5625573	protein synthesis	ribosomal protein S27A
YLR090W	XDJ1______	-1.05	336082	320326	unknown	unknown; similar to E.coli dnaJ
YLR460C	__________	-1.10	158729	144860	unknown	unknown; similar to Ycr102p
YMR193W	MRPL24____	+1.05	345307	362017	protein synthesis	ribosomal protein, mitochondrial L24
YNL251C	NRD1______	-1.08	172816	160597	transcription	elongation; also mRNA abundance
YOL155C	__________	-1.06	251148	236851	unknown	unknown; similar to S. cerevisiae glucan 1,4-alpha-glucosidase
YOR365C	__________	-1.10	174890	159000	unknown	unknown
YPR062W	FCY1______	-1.12	1865323	1672201	pyrimidine metabolism	cytosine deaminase
YBR040W	FIG1______	-1.08	105347	97842	mating	extracellular integral membrane protein
YCL063W	__________	-1.14	123954	108686	unknown	unknown; similar to plant aminocyclopropane-1-carboxylate
YDL157C	__________	+1.06	346217	366927	unknown	unknown
YDR278C	__________	+1.01	102339	103471	unknown	unknown
YEL061C	CIN8______	-1.06	780237	733398	mitosis, spindle maintenance	kinesin related protein
YGR080W	TWF1______	+1.12	396026	444399	cytoskeleton	twifilin; actin monomer sequestering protein
YHR094C	HXT1______	-1.40	3496899	2506364	transport	hexose permease
YJR126C	__________	-1.14	427063	373106	unknown	unknown; similar to transferrin receptor
YLR274W	CDC46_____	-1.21	342341	283770	DNA replication	MCM initiator complex
YMR013C	SEC59_____	+1.00	256686	257442	protein glycosylation	mannosyltransferase (putative)
YNL059C	ARP5______	-1.05	381463	364962	cytoskeleton (putative)	actin-related protein
YOR179C	__________	-1.12	243300	217280	unknown	unknown
YPL157W	__________	-1.13	327855	290027	unknown	unknown
YAR008W	SEN34_____	-1.00	145690	145616	tRNA splicing	splicing endonuclease subunit
YBR240C	THI2______	-1.07	98401	92012	thiamine biosynthesis	transcription factor
YDR109C	__________	-1.04	218965	210104	unknown	unknown; similar to FGGY kinase family (GB:Z48758)
YDR478W	SNM1______	+1.05	196075	206536	rRNA processing	RNase MRP component
YGL171W	ROK1______	-1.31	648277	494580	rRNA processing	RNA helicase
YGR278W	__________	+1.02	263057	267381	unknown	unknown
YJL172W	CPS1______	+1.44	244132	351639	protein degradation	vacuolar carboxypeptidase yscS
YKL168C	KKQ8______	+1.02	163932	166568	unknown	protein kinase
YLR102C	APC9______	+1.07	160157	171947	cell cycle	anaphase-promoting complex subunit
YMR204C	__________	-1.05	182457	174046	unknown	unknown
YNL263C	YIF1______	-1.02	612433	600032	unknown	interacts with Yip1p; similar to NADH dehydrogenases
YOR001W	RRP6______	-1.23	550628	448079	rRNA processing, 5.8S	unknown
YOR377W	ATF1______	-1.44	265968	184388	acetate ester biosynthesis	alcohol acetyltransferase
YPR074C	TKL1______	-1.01	122959	122123	pentose phosphate cycle	transketolase
YBR052C	__________	+1.30	440928	573291	unknown	unknown; similar to Ycp4p, S. pombe obr1, and E. coli trp
YCLX02C	__________	-1.33	129013	97012
YDL169C	UGX2______	+1.16	113642	132023	unknown	unknown
YDR290W	__________	-1.09	108266	99387	unknown	unknown
YEL073C	__________	+1.06	126357	133787	unknown	unknown
YGR092W	DBF2______	+1.09	307861	336105	cell cycle	late mitosis; protein kinase
YHR106W	TRR2______	-1.50	924436	617051	pyrimidine biosynthesis	thioredoxin reductase
YJR138W	IML1______	-1.15	129369	112284	plasmid maintenance (outative)	unknown
YLR286C	CTS1______	+1.23	2051285	2514719	cell wall biogenesis	endochitinase
YMR025W	__________	+1.03	181568	187831	unknown	unknown
YNL071W	LAT1______	+1.13	3378710	3817738	glycolysis	dihydrolipoamide S-acetyltransferase
YOR191W	RIS1______	-1.12	418482	374764	silencing	SNF2 family DNA-dependent ATPase
YPL169C	MEX67_____	-1.23	462906	377324	mRNA export	poly(A)+RNA binding protein
YAR030C	__________	+1.13	125057	141354	unknown	unknown
YBR252W	DUT1______	+1.02	721770	738475	pyrimidine metabolism	dUTP pyrophosphatase
YDR121W	DPB4______	+1.05	501233	526462	DNA replication	DNA polymerase epsilon subunit
YDR490C	PKH1______	+1.19	271986	322771	unknown	protein kinase (ser/thr)
YER176W	ECM32_____	-1.05	206174	195494	cell wall biogenesis	DNA helicase I
YGL183C	__________	-1.09	170368	156467	unknown	unknown
YGR290W	__________	-1.35	174288	129570	unknown	unknown
YIL082W	__________	-1.03	315122	306316	unknown	unknown
YJL184W	__________	+1.04	637436	664387	unknown	unknown
YKL180W	RPL17A____	+1.20	15821417	19025262	protein synthesis	ribosomal protein L17A
YLR114C	EFR4______	-1.29	590621	457028	unknown	unknown; similar to Drosophila bicaudal-D protein; null requires PHO85
YMR216C	SKY1______	-1.23	289601	234638	unknown	protein kinase
YNL275W	__________	-1.21	208986	173153	unknown	unknown; similar to human band 3 anion transport protein
YOR013W	__________	-1.02	206841	203401	unknown	unknown
YOR389W	__________	-1.19	244329	204550	unknown	unknown
YPR086W	SUA7______	-1.31	657064	502982	transcription	TFIIB subunit
YBR064W	__________	+1.06	109241	115333	unknown	unknown
YCR002C	CDC10_____	+1.04	858039	889165	cytokinesis	septin
YDL181W	INH1______	+1.71	420895	720681	ATP synthesis	mitochondrial ATPase inhibitor
YDR302W	GPI11_____	+1.06	356147	377680	protein processing	GPI-phosphoethanolamine transferase subunit
YGR104C	SRB5______	-1.00	283937	282869	transcription	RNA polymerase II mediator subunit
YHR118C	ORC6______	-1.05	764416	725035	DNA replication	origin recognition complex, 50 KD subunit
YJR150C	DAN1______	-1.31	204585	155582	unknown	unknown; induced during anaerobic growth
YLR297W	__________	+1.50	209802	313956	unknown	unknown
YMR036C	MIH1______	-1.05	175013	166853	cell cycle	M-phase phosphatase
YNL083W	__________	-1.11	133221	119880	unknown	unknown; mitochondrial carrier (MCF) family
YOR201C	PET56_____	-1.05	326553	309549	rRNA processing, mitochondrial	ribose methyltransferase
YPL181W	__________	-1.01	112706	111312	unknown	unknown
YBL003C	HTA2______	+1.12	6937510	7742202	chromatin structure	histone H2A
YBR264C	YPT10_____	-1.11	460845	414178	unknown	unknown; similar to rab proteins and other small GTP-binding
YDL003W	MCD1______	-1.31	478639	366497	mitosis, sister chromatid cohesion	unknown
YDR133C	__________	+1.18	15453859	18310056	unknown	unknown
YDR502C	SAM2______	-1.42	2349886	1649097	methionine biosynthesis	regulator; S-adenosylmethionine synthetase
YFL001W	DEG1______	-1.04	220366	212421	tRNA processing	pseudouridine synthase
YGL195W	GCN1______	+1.11	120939	134750	protein synthesis	translation activator of GCN4
YHL002W	__________	+1.13	338025	380576	unknown	unknown
YIL094C	LYS12_____	-1.17	1835434	1570363	lysine biosynthesis	homo-isocitrate dehydrogenase
YJL196C	ELO1______	+1.24	914283	1135325	fatty acid metabolism	fatty acid elongation protein
YKL192C	ACP1______	+1.14	944743	1077517	fatty acid biosynthesis	mitochondrial acyl carrier protein
YLR126C	__________	+1.26	183275	230252	unknown	unknown; similar to Pseudomonas aeroginosa anthranilate
YML003W	__________	-1.05	120616	115070	unknown	unknown
YMR228W	MTF1______	+1.01	196420	198596	transcription	mitochondrial RNA polymerase specificity factor
YNL285W	__________	+1.10	177769	196108	unknown	unknown
YOR025W	HST3______	-1.28	400379	313062	silencing	unknown
YPL003W	ULA1______	+1.12	270463	303576	protein degradation, Rub1p-mediated	Rub1p activating protein
YPR098C	__________	+1.34	363495	486763	unknown	unknown
YBR076W	ECM8______	+1.21	130377	157305	cell wall biogenesis	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YCR014C	POL4______	-1.07	192514	180382	DNA repair	DNA polymerase IV
YDL193W	__________	-1.36	338929	249854	unknown	unknown
YDR314C	__________	-1.16	115757	99818	unknown	unknown
YER016W	BIM1______	-1.08	607143	564163	cytoskeleton	microtubule binding protein
YGL003C	CDH1______	-1.16	175813	151511	cell cycle	cyclin degradation
YGR114C	__________	-1.05	185763	176988	unknown	unknown
YHR130C	__________	+1.09	106079	115542	unknown	unknown
YJL003W	__________	+1.07	220993	235432	unknown	unknown
YKL003C	MRP17_____	+1.07	426883	458342	protein synthesis	ribosomal protein, mitochondrial small subunit
YLL003W	SFI1______	+1.05	215589	226276	unknown	unknown
YLR309C	IMH1______	-1.08	182136	169066	secretion (putative)	unknown; suppresses ypt6 ts mutation
YMR047C	NUP116____	-1.18	726616	614250	nuclear protein targeting	nuclear pore protein
YNL095C	__________	-1.14	201564	177380	unknown	unknown; similar to Ecm3p
YOL003C	__________	+1.07	337502	360520	unknown	unknown
YOR213C	SAS5______	-1.03	264806	255934	silencing	unknown
YPL192C	__________	-1.04	251370	242137	unknown	unknown
YAR053W	__________	+1.00	139675	139870	unknown	unknown
YBL013W	FMT1______	-1.08	116901	108092	tRNA processing	met-tRNA formyltransferase
YBR276C	PPS1______	-1.07	363859	338957	unknown	protein phosphatase
YDL015C	__________	-1.38	852270	618299	unknown	unknown; similar to rat synaptic glycoprotein SC2
YDR145W	TAF61_____	-1.03	2600544	2532993	transcription	TFIID 61 kDsubunit
YDR514C	__________	-1.12	519637	463147	unknown	unknown
YFL012W	__________	-1.05	120012	114518	unknown	unknown
YGL207W	SPT16_____	-1.23	397895	324770	chromatin structure	non-histone protein
YHL011C	PRS3______	-1.08	251598	233151	purine biosynthesis	ribose-phosphate pyrophosphokinase 3
YIL105C	__________	-1.08	5888840	5444013	unknown	unknown; similar to Ask10p and Ynl047p
YJL208C	NUC1______	-1.07	423522	396900	mitochondrial recombination	endonuclease
YKL204W	EAP1______	+1.01	116457	117931	translation	unknown; associates with translation initiation factor eIF4E
YLR138W	NHA1______	-1.01	259051	256970	transport (putative)	Na+/H+ antiporter
YML012W	ERV25_____	+1.04	520941	539254	secretion	vesicle coat component
YMR240C	CUS1______	-1.07	512508	480522	mRNA splicing	U2 snRNP protein
YNL297C	MON2______	-1.04	104367	100410	secretion (putative)	unknown; brefeldin A sensitive; monensin sensitive
YOR037W	CYC2______	-1.04	281519	270806	mitochondrial protein targeting	cytochrome c import factor
YPL015C	HST2______	-1.01	298447	296762	unknown	similar to Sir2p
YPR110C	RPC40_____	-1.41	1400534	992551	transcription	RNA polymerase III 40 kD subunit
YBR087W	RFC5______	-1.12	416908	371805	DNA replication	DNA polymerase processivity factor
YCR024C	PMP1______	-1.82	1289581	706953	H+ homeostasis	regulates plasma membrane H+-ATPase
YDL205C	HEM3______	-1.85	299891	162091	heme biosynthesis	phorphobilinogen deaminase (uroporphyrinogen synthase)
YDR324C	__________	-1.75	422469	241336	unknown	unknown; similar to G-protein beta subunits
YER027C	GAL83_____	-1.30	407424	312919	glucose repression	component of Snf1 complex
YGL015C	__________	-1.12	145854	130100	unknown	unknown
YGR126W	__________	+1.15	107868	123694	unknown	unknown
YHR140W	__________	+1.18	127839	151291	unknown	unknown
YJL015C	__________	+1.10	237446	260967	unknown	unknown
YKL014C	__________	-1.14	423595	372830	unknown	unknown
YLL015W	BPT1______	+1.05	283500	296876	transport	bile pigment transporter
YLR320W	__________	+1.11	96295	106930	unknown	unknown
YMR057C	__________	-1.10	116382	105947	unknown	unknown
YNL107W	YAF9______	+1.07	302466	323640	unknown	unknown; similar to human AF-9 protein
YOL015W	__________	-1.12	128781	115402	unknown	unknown
YOR225W	__________	+1.04	366151	380235	unknown	unknown
YPL204W	HRR25_____	-1.05	760732	725377	DNA repair	casein kinase I isoform
YBL025W	RRN10_____	-1.29	158178	122822	transcription	component of upstream activation factor complex (UAF)
YBR288C	APM3______	-1.24	259713	209266	vacuolar protein targeting	AP-3 complex subunit
YDL027C	__________	+1.05	226067	238102	unknown	unknown
YDR157W	__________	-1.17	345343	294188	unknown	unknown
YDR526C	__________	-1.64	265149	161870	unknown	unknown
YFL021W	GAT1______	+1.11	206356	228560	nitrogen catabolism	transcription factor
YGL219C	__________	-1.03	268610	261968	unknown	unknown; similar to Mycoplasma genitalium threoninyl-tRNA
YHL023C	__________	-1.08	242564	224676	unknown	unknown
YIL117C	__________	+2.53	358672	907466	unknown	unknown
YJL220W	__________	+1.16	110567	128209	unknown	unknown; similar to alpha-D-glucosidase (maltase)
YKL216W	URA1______	+1.20	3013258	3627349	pyrimidine biosynthesis	dihydroorotate dehydrogenase
YLR150W	STM1______	-1.32	10858516	8204411	unknown	unknown; suppressor of tom1 and pop2 mutations
YMR252C	__________	+1.11	211012	233971	unknown	unknown
YNL309W	STB1______	-1.11	163724	147040	unknown	binds Sin3p
YOR049C	__________	-1.06	242746	228539	unknown	unknown
YPL027W	__________	-1.11	122072	110038	unknown	unknown
YPR122W	AXL1______	-1.03	98683	95352	bud site selection, axial	unknown; insulin-degrading enzyme homolog
YBR098W	MMS4______	-1.01	95833	95023	methylmethanesulfonate resistance	transcription activator (putative)
YCR035C	RRP43_____	-1.10	191587	174381	rRNA processing	exoribonuclease
YDL217C	TIM22_____	-1.24	326952	264257	mitochondrial protein targeting	inner membrane carrier protein
YDR336W	__________	-1.02	208487	204099	unknown	unknown
YGL027C	CWH41_____	-1.08	485281	450908	cell wall biogenesis	beta-1,6-glucan assembly protein
YGR138C	__________	+1.80	415549	749446	unknown	major facilitator superfamily
YHR151C	__________	+1.03	213037	220201	unknown	unknown
YJL027C	__________	+1.12	104795	117302	unknown	unknown
YKL026C	GPX1______	+1.17	95515	111565	glutathione metabolism (putative)	glutathione peroxidase (putative)
YLL027W	ISA1______	+1.14	407782	463157	unknown	unknown; Iron Sulfur Assembly -- IscA/NifA homolog
YLR332W	MID2______	+1.51	385350	583193	mating (putative)	unknown; mutant is sensitive to matin pheromone
YMR069W	__________	+1.03	107928	111513	unknown	unknown
YNL119W	__________	-1.08	1363118	1267836	unknown	unknown
YOL027C	__________	-1.16	375460	323989	unknown	unknown
YOR237W	HES1______	-1.07	151116	141327	sterol metabolism	unknown
YPL216W	__________	-1.07	262057	245738	unknown	unknown
YER188W	__________	+1.04	150825	157075	unknown	unknown
YBL037W	APL3______	-1.17	116959	99975	secretion	clathrin associated
YBR300C	__________	-1.18	148620	125905	unknown	unknown
YDL039C	__________	-1.23	304282	248281	unknown	unknown
YDR169C	STB3______	-1.31	226543	172619	unknown	binds Sin3p
YDR538W	PAD1______	-1.47	210289	143476	phenylacrylic acid resistance	phenylacrylic acid decarboxylase
YFL032W	__________	-1.18	173419	147056	unknown	unknown
YGL230C	__________	+1.15	117116	135016	unknown	unknown
YHL034C	SBP1______	-1.00	3046414	3032522	RNA processing	single stranded nucleic acid binding protein
YIL129C	TAO3______	+1.16	436238	504384	transcription (putative)	unknown; transcripiotnal activator of OCH1
YJR008W	__________	+1.21	203842	245675	unknown	unknown
YKR003W	__________	+1.33	312321	414152	unknown	unknown; similar to human oxysterol-binding protein
YLR160C	ASP3-4____	+1.12	118015	132513	asparagine utilization	L-asparaginase II
YML034W	SRC1______	-1.09	136743	125161	unknown	unknown; induced at G2/M
YMR264W	CUE1______	+1.09	729668	793126	protein degradation, ubiquitin-mediated	recruits enzyme Ubc7p to membrane

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL321W	__________	-1.05	142739	136029	unknown	unknown; calcium permease family
YOR061W	CKA2______	-1.03	137530	133483	cell cycle	casein kinase II
YPL039W	__________	-1.07	158541	147957	unknown	unknown
YPR134W	MSS18_____	+1.11	269642	300395	mRNA splicing, COX1 mRNA	unknown
YCR047C	__________	-1.38	669021	485604	unknown	unknown; similar to rat methylglycine transferase
YDL229W	SSB1______	-1.13	116903	103909	translation	cytosolic HSP70
YDR348C	__________	-1.14	256155	224592	unknown	unknown
YER048C	CAJ1______	-1.14	866326	762317	unknown	unknown; similar to E. coli DnaJ
YGL039W	__________	-1.08	453666	421864	unknown	unknown
YGR150C	__________	-1.02	275841	269281	unknown	unknown; similar to Yjl083p
YHR163W	SOL3______	-1.07	854896	800026	tRNA splicing, putative	unknown
YJL039C	NUP192____	-1.22	310138	254987	nuclear protein targeting	nuclear pore protein
YKL037W	__________	+1.12	152849	171425	unknown	unknown
YLL039C	UBI4______	-1.16	14908166	12828557	protein degradation, ubiquitin-mediated	ubiquitin
YLR344W	RPL26A____	+1.11	12126455	13433964	protein synthesis	ribosomal protein L26A
YMR080C	NAM7______	-1.43	477044	334058	mRNA decay	RNA helicase, putative
YNL131W	TOM22_____	-1.06	999246	946787	mitochondrial protein targeting	outer membrane translocase component
YOL039W	RPP2A_____	+1.20	15798264	18917268	protein synthesis	ribosomal protein P2A/L44, acidic
YOR249C	APC5______	-1.12	479069	426867	mitosis	anaphase-promoting complex subunit
YPL228W	CET1______	-1.33	462077	346950	mRNA capping	capping enzyme beta subunit, RNA 5'-triphosphatase
YHR219W	__________	-1.08	1679397	1562111	unknown	unknown; similar to other subtelomerically-encoded proteins
YBL049W	__________	-1.01	110843	110035	unknown	unknown
YDL051W	LHP1______	-1.33	868517	653411	tRNA processing	RNA binding protein
YDR179C	__________	+1.08	158807	171247	unknown	unknown
YFL042C	__________	-1.11	139542	125831	unknown	unknown; similar to Yhr080p
YGL242C	__________	+1.31	554503	727775	unknown	unknown; similar to ankyrin and coiled-coil proteins
YHL046C	__________	+1.32	297984	392080	unknown	unknown; similar to members of the Srp1p/Tip1p family
YIL141W	__________	-1.04	125481	120480	unknown	unknown
YJR019C	TES1______	+1.14	145278	165691	fatty acid metabolism	peroxisomal acyl-CoA thioesterase
YKR015C	__________	+1.11	155724	173438	unknown	unknown
YLR172C	DPH5______	-1.10	1290877	1170190	diphthamide biosynthesis	diphthamide methyltransferase
YMR276W	DSK2______	-1.05	933164	886961	spindle pole body dupl	ubiquitin-like protein
YNL333W	SNZ2______	+1.03	276548	284020	unknown	unknown; induced in stationary phase
YOR073W	__________	-1.07	308927	288295	unknown	unknown
YPL051W	ARL3______	+1.13	310950	350332	unknown	unknown; Similar to ADP-ribosylation factor
YPR144C	__________	-1.26	416229	331370	unknown	unknown; similar to RNA polymerase beta subunit
YBR121C	GRS1______	-1.16	2666166	2304395	protein synthesis	tRNA synthase, glycyl
YCR059C	__________	-1.22	497267	406883	unknown	unknown
YDL241W	__________	-1.19	284493	238753	unknown	unknown
YDR360W	__________	-1.14	119114	104170	unknown	unknown
YER059W	PCL6______	+1.15	213406	245799	cell cycle	cyclin (Pho85p)
YGL051W	__________	-1.02	251984	246271	unknown	unknown
YHR175W	CTR2______	+1.12	510131	571846	transport	copper transporter
YJL052W	TDH1______	+1.19	15958128	19058769	glycolysis	glyceraldehyde-3-phosphate dehydrogenase 1
YKL049C	CSE4______	+1.05	562231	592529	chromatin structure, centromeric	histone-related
YLL051C	FRE6______	-1.30	481879	371433	unknown	unknown; similar to ferric reductase Fre2p
YLR356W	__________	+1.19	217902	260214	unknown	unknown; similar to Scm4p, possible Cdc4p-interacting
YMR091C	NPL6______	-1.13	759819	672853	nuclear protein targeting	unknown
YNL143C	__________	-1.26	539124	427297	unknown	unknown
YOL051W	GAL11_____	-1.08	1666146	1535851	transcription	RNA polymerase II mediator subunit
YOR261C	RPN8______	+1.06	1548960	1639587	protein degradation	26S proteasome regulatory subunit
YPL240C	HSP82_____	-1.67	4868728	2909624	protein folding	HSP90 homolog
YJR162C	__________	-1.03	168279	162979	unknown	unknown; similar to subtelomerically-encoded proteins
YBL061C	SKT5______	+1.05	160063	167566	cell wall biogenesis	chitin synthase regulator
YDL063C	__________	-1.20	441993	368990	unknown	unknown
YDR190C	RVB1______	-1.01	1084878	1075509	unknown	unknown; similar to RUVB
YFL054C	__________	-1.03	119852	116443	unknown	unknown; similar to Fps1p and Ypr192p transmembrane channels
YGL254W	FZF1______	-1.07	173839	162008	sulfite metabolism	(putative) transcription factor
YIL153W	RRD1______	-1.01	421857	418966	drug resistance	unknown
YJR030C	__________	-1.14	315066	276534	unknown	unknown
YKR027W	__________	-1.12	189060	168971	unknown	unknown
YLR184W	__________	+1.07	95909	102190	unknown	unknown
YML055W	SPC2______	+1.32	451911	596181	secretion	signal peptidase subunit
YMR288W	__________	+1.01	104615	105436	unknown	unknown
YNR006W	VPS27_____	-1.01	234475	233134	vacuolar protein targeting	component of class E protein complex
YOR085W	OST3______	-1.07	363331	338892	protein glycosylation	oligosaccharyltransferase complex subunit
YPL061W	ALD6______	+1.38	2427823	3351124	ethanol utilization	acetaldehyde dehydrogenase
YPR156C	__________	+1.46	346868	505128	unknown	major facilitator superfamily
YBR133C	HSL7______	-1.09	258493	237315	cell cycle	Swe1p (kinase) regulator
YCR070W	__________	+1.23	508437	623489
YDR005C	MAF1______	+1.08	276794	298545	protein targeting (putative)	unknown
YDR370C	__________	-1.12	344350	308012	unknown	unknown
YER068W	MOT2______	-1.14	225289	197613	mating	transcriptional regulator
YGL063W	PUS2______	-1.02	149669	147031	tRNA processing	pseudouridine synthase
YGR170W	PSD2______	-1.04	213020	205765	phospholipid metabolism	phosphatidylserine decarboxylase 2
YHR187W	IKI1______	-1.00	356703	355281	killer toxin sensitivity	unknown
YJL064W	__________	-1.17	345239	295449	unknown	unknown
YKL061W	__________	+1.34	260736	348852	unknown	unknown
YLL063C	AYT1______	+1.04	180510	187183	unknown	transacetylase (putative)
YLR368W	__________	+1.09	199231	216312	unknown	unknown
YMR103C	__________	-1.01	109819	108995	unknown	unknown
YNL155W	__________	+1.15	549188	631003	unknown	unknown
YOL061W	PRS5______	+1.01	853261	858040	purine, pyrimidine, tryptophan and histidine biosynthesis	phosphoribosylpyrophosphate synthetase
YOR273C	__________	+1.13	168701	190523	unknown	unknown; similar to members of major facilitator superfamily
YPL251W	__________	-1.44	545929	378210	unknown	unknown
YMR318C	__________	-1.23	1615314	1316673	unknown	unknown; similar to alcohol-dehydrogenases
YBL073W	__________	-1.11	131076	118012	unknown	unknown
YDL075W	RPL31A____	+1.07	15474127	16527809	protein synthesis	ribosomal protein L31A
YDR202C	RAV2______	+1.13	564173	639518	vacuolar acidification (putative)	unknown; regulates V-ATPase
YFL066C	__________	-2.11	442787	210079	unknown	unknown; similar to other subtelomerically-encoded proteins
YGR003W	__________	-1.03	146399	141547	unknown	unknown
YHR017W	YSC83_____	+1.17	282501	331612	unknown	unknown; similar to S.douglasii YSD83
YIL164C	NIT1______	-1.15	237707	207190	unknown	nitrilase
YJR042W	NUP85_____	+1.05	121027	127415	nuclear protein targeting	nuclear pore protein
YKR039W	GAP1______	+1.13	134108	151213	transport	general amino acid permease
YLR196W	PWP1______	-1.23	766547	622565	unknown	unknown; similar to beta-transducin superfamily
YML066C	__________	-1.11	246016	220973	unknown	unknown
YMR298W	__________	-1.01	665459	659877	unknown	unknown
YNR018W	__________	+1.09	1035290	1124595	unknown	unknown
YOR097C	__________	+1.30	282889	366494	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YPL073C	__________	+1.11	123716	137485	unknown	unknown
YPR164W	KIM3______	-1.01	114287	113393	diepoxybutane and mitomycin C resistance	unknown
YBR145W	ADH5______	-2.12	917428	431878	glycolysis	alcohol dehydrogenase V
YCR083W	TRX3______	+1.13	203178	228786	oxidative stress response	thioredoxin, mitochondrial
YDR017C	KCS1______	-1.15	666988	578359	cell wall organization	(putative) transcription factor
YDR382W	RPP2B_____	+1.20	15852473	19072376	protein synthesis	ribosomal protein L45, acidic
YER079W	__________	-1.00	281471	280794	unknown	unknown
YGL075C	MPS2______	+1.05	173000	181479	cytoskeleton	spindle pole body duplication; nuclear envelope/ER protein
YGR182C	__________	+1.30	1042635	1351616	unknown	unknown
YHR199C	__________	+1.02	550404	559974	unknown	unknown; similar to Yhr198p
YJL076W	NET1______	-1.20	185988	154490	silencing	unknown
YKL073W	LHS1______	+1.07	355684	380527	secretion	chaperone; ER protein translocation
YLR008C	__________	+1.01	125941	127654	unknown	unknown
YLR380W	CSR1______	-1.10	455432	413199	unknown	unknown; multicopy suppressor of chs5 spa2 double mutant
YMR115W	__________	-1.02	333536	327261	unknown	unknown
YNL167C	SKO1______	-1.11	228436	206686	transcription	CREB-like transcriptional repressor
YOL073C	__________	+1.14	287309	328824	unknown	unknown
YOR285W	__________	+1.43	1020039	1459031	unknown	unknown; similar to Drosophila melanogaster heat shock
YPL261C	__________	+1.02	115542	117365	unknown	unknown
YBL085W	BOI1______	+1.05	91173	96142	bud growth	binds Bem1p
YDL087C	LUC7______	-1.00	147047	146984	mRNA processing (putative)	unknown; synthetic lethal with cap-binding complex
YFR010W	UBP6______	+1.10	617128	678066	protein degradation, ubiquitin-mediated	deubiquitinating enzyme (putative)
YGR015C	__________	+1.02	179163	182623	unknown	unknown
YHR028C	DAP2______	-1.07	489429	458311	protein degradation	dipeptidyl aminopeptidase B
YIL175W	__________	-1.19	208802	175715	unknown	unknown
YJR054W	__________	+1.16	327791	381214	unknown	unknown
YKR051W	__________	-1.20	337716	280957	unknown	unknown
YLR208W	SEC13_____	-1.12	1180883	1050562	secretion	vesicle coat component
YML078W	CPR3______	+1.20	2086457	2495764	protein folding	peptidyl-prolyl cis-trans isomerase
YMR308C	PSE1______	-1.35	487117	361731	nuclear protein targeting	beta-karyopherin
YNR030W	ECM39_____	+1.01	383605	387958	cell wall biogenesis	unknown
YOR109W	INP53_____	-1.17	585230	501478	vesicle trafficking; phosphatidylinositol metabolism	inositol polyphosphate 5-phosphatase
YPL085W	SEC16_____	-1.02	119871	117554	secretion	vesicle coat component
YPR176C	BET2______	-1.05	657633	625321	protein processing	geranylgeranyltransferase type II beta subunit
YBR157C	ICS2______	+1.09	140823	153676	Cu2+ ion homeostasis (putative)	unknown
YCR094W	CDC50_____	+1.04	257212	267539	cell cycle	unknown
YDR029W	__________	+1.17	113849	133281	unknown	unknown
YDR394W	RPT3______	+1.08	768305	826424	protein degradation	26S proteasome subunit
YER090W	TRP2______	-1.04	757861	729531	tryptophan biosynthesis	anthranilate synthase component I
YGL087C	MMS2______	+1.39	330387	458877	DNA repair, postreplication	unknown
YGR194C	XKS1______	+1.11	212461	235002	xylulose utilization	xylulokinase
YHR211W	FLO5______	-1.05	289172	274799	flocculation	flocculin, similar to Flo1p
YJL088W	ARG3______	+1.18	257863	303785	arginine biosynthesis	ornithine carbamoyltransferase
YKL085W	MDH1______	-1.21	696632	575566	TCA cycle	malate dehydrogenase
YLR020C	__________	-1.13	136929	121048	unknown	unknown; similar to triacylglycerol lipase
YLR392C	__________	-1.04	175200	168513	unknown	unknown
YMR126C	__________	-1.05	276297	263398	unknown	unknown
YNL179C	__________	-1.08	423757	391779	unknown	unknown
YOL085C	__________	-1.01	131388	129475	unknown	unknown
YOR297C	TIM18_____	-1.07	349581	327942	mitochondrial protein targeting	inner membrane translocase component
YPL273W	SAM4______	-1.23	1671457	1363725	sulfur amino acid metabolism	S-adenosylmethionine:homocysteine S-methyltransferase
YAL004W	__________	-1.13	144717	127846	unknown	unknown
YBR169C	SSE2______	-1.22	321456	264143	heat shock response	HSP70 family
YCR106W	__________	-1.91	306096	160447	unknown	unknown; similar to transcription factors
YDR040C	ENA1______	-1.21	420375	346173	transport	plasma membrane ATPase
YDR407C	TRS120____	-1.40	503437	358531	secretion (putative)	transport protein particle (TRAPP) subunit, 120 kD
YER102W	RPS8B_____	+1.18	15942991	18761555	protein synthesis	ribosomal protein S8B
YGL100W	SEH1______	-1.09	1020026	938174	nuclear protein targeting	nuclear pore protein
YGR207C	__________	+1.30	773320	1003059	unknown	electron-transferring flavoprotein, beta chain (putative)
YIL004C	BET1______	+1.13	380060	429327	secretion	vesicle recycling; SNARE
YJL101C	GSH1______	-1.01	416763	412025	glutathione biosynthesis	gamma-glutamylcysteine synthetase
YKL096W	CWP2______	+1.19	15877377	18955412	unknown	cell wall protein
YLR033W	__________	-1.01	226803	223945	unknown	involved in temperature-sensitive growth and in pheromone response pathway
YLR405W	__________	-1.21	459915	380096	unknown	unknown
YMR138W	CIN4______	-1.04	246409	236500	mitosis, chromosome segregation	GTP-binding protein
YNL192W	CHS1______	-1.01	101318	100421	cytokinesis	chitin synthase
YOL098C	__________	-1.37	875040	636695	unknown	unknown
YOR308C	SNU66_____	-1.24	174746	141231	mRNA splicing (putative)	U4/U6.U5 snRNP protein
YPR003C	__________	-1.03	151087	147228	unknown	unknown; similar to Sul1p and sulfate transporters from
YBL098W	__________	-1.04	226134	216784	unknown	unknown; similar to bacterial NADP/NAD-dependent
YCL003W	__________	-1.20	132594	110175
YDL100C	__________	-1.17	466804	400358	unknown	unknown; similar to E. coli arsenical pump-driving ATPase
YDR223W	__________	-1.07	123465	115801	unknown	unknown
YEL004W	YEA4______	-1.17	145973	124264	unknown	unknown; similar to GOG5, a gene involved in vanadate
YFR023W	PES4______	-1.07	106431	99496	DNA replication	unknown; suppresses DNA polymerase epsilon mutation
YHR040W	__________	-1.25	302255	241147	unknown	unknown; similar to Hit1p, expressed under
YIR011C	STS1______	+1.08	502027	542090	nuclear protein targeting	Rna15 transport factor
YJR067C	YAE1______	-1.00	290148	289435	unknown	unknown
YKR064W	__________	+1.07	111035	118563	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YLR221C	__________	-1.16	821769	708110	unknown	unknown
YML091C	RPM2______	-1.18	490414	416078	tRNA processing, mitochondrial	RNase P subunit
YNL004W	HRB1______	-1.07	496624	463515	unknown	RNA binding protein (putative)
YNR043W	MVD1______	-1.10	1711251	1560653	sterol metabolism	mevalonate pyrophosphate decarboxylase
YOR122C	PFY1______	+1.12	2796281	3140748	cytoskeleton	profilin
YPL098C	__________	+1.08	555356	598764	unknown	unknown
YPR189W	SKI3______	-1.08	126979	117713	mRNA decay and virus resistance	unknown
YAL017W	FUN31_____	-1.24	352288	283776	unknown	putative protein kinase
YBR181C	RPS6B_____	+1.05	15916150	16636816	protein synthesis	ribosomal protein S6B
YCRX11W	__________	-1.09	224415	205410
YDR052C	DBF4______	-1.32	180740	136841	cell cycle	Cdc7p (kinase) regulator
YDR419W	RAD30_____	-1.05	123889	117582	DNA repair	unknown
YER114C	BOI2______	-1.33	206133	154597	bud emergence	binds Bem1p
YGL112C	TAF60_____	+1.00	407623	408449	transcription	TFIID 60 kD subunit
YGR219W	__________	+1.17	303078	353423	unknown	unknown
YIL015W	BAR1______	+1.17	116488	136625	mating	alpha-factor degradation
YJL113W	__________	+1.05	101055	106454	unknown	unknown
YKL109W	HAP4______	-1.18	265976	226088	transcription	component of heterotrimeric CCAAT-binding factor
YLR043C	TRX1______	+1.29	1625260	2096882	DNA replication	thioredoxin I
YLR415C	__________	-1.05	114202	108544	unknown	unknown
YMR150C	IMP1______	+1.16	342451	397906	protein processing	mitochondrial inner membrane protease

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL204C	SPS18_____	-1.04	131109	125988	sporulation	unknown
YOL108C	INO4______	+1.13	263819	297356	phospholipid biosynthesis	transcription factor
YOR320C	__________	+1.01	534184	539522	unknown	unknown
YPR015C	__________	-1.07	166614	156022	unknown	unknown; similar to human GT box-binding protein
YBL108W	__________	-1.13	108797	95899	unknown	unknown
YCL016C	__________	-1.49	163849	109675	unknown	unknown
YDL112W	TRM3______	-1.12	100894	90481	tRNA processing	tRNA robose methylase
YEL016C	__________	-1.23	146036	118426	unknown	unknown; similar to Ycr026p
YFR033C	QCR6______	-1.61	1526988	950198	oxidative phosphorylation	ubiquinol cytochrome-c reductase subunit
YGR038W	ORM1______	+1.03	524148	538682	unknown	unknown
YHR051W	COX6______	+1.14	917169	1042579	oxidative phosphorylation	cytochrome-c oxidase subunit VI
YIR021W	MRS1______	-1.03	169267	164069	mRNA splicing, COB mRNA	unknown
YJR079W	__________	+1.10	109032	119477	unknown	unknown
YKR076W	ECM4______	+1.30	142303	184675	cell wall biogenesis	unknown
YLR231C	__________	+1.57	320842	503190	unknown	unknown; similar to rat kynureninase (PIR:PS0370)
YML101C	__________	+1.15	326251	374936	unknown	unknown
YNL016W	PUB1______	-1.24	2316873	1865096	mRNA processing	poly(A)+ RNA-binding protein
YNR055C	HOL1______	-1.19	781290	654570	transport	(putative) multidrug resistance permease
YOR134W	BAG7______	-1.00	166037	165224	signaling	GTPase activating protein
YPL110C	__________	-1.08	105199	97508	unknown	unknown; similar to Pho81p
YPR201W	ARR3______	-1.30	190431	145944	arsenic resistance	arsenite transporter
YAL028W	__________	-1.23	147242	119335	unknown	unknown
YBR193C	MED8______	-1.27	147845	116320	transcription	RNA polymerase II mediator subunit
YDR064W	RPS13_____	-1.05	5796198	5537337	protein synthesis	ribosomal protein S13
YDR431W	__________	-1.26	125877	100231	unknown	unknown
YER125W	RSP5______	-1.69	445539	263534	protein degradation, ubiquitin-mediated	ubiquitin-protein ligase (E3 enzyme)
YGL124C	MON1______	-1.02	171758	168851	secretion (putative)	unknown; brefeldin A sensitive; monensin sensitive
YGR231C	PHB2______	+1.14	912141	1038380	aging	prohibitin homolog
YIL027C	__________	+1.11	248198	275822	unknown	unknown
YJL125C	GCD14_____	-1.11	479786	431032	protein synthesis	translation repressor of GCN4
YKL121W	__________	+1.10	111099	122189	unknown	unknown
YLR055C	SPT8______	-1.07	794993	740369	chromatin structure	histone acetyltransferase complex subunit
YLR425W	TUS1______	-1.13	177351	156997	unknown	unknown; interacts with Sec1p
YMR160W	__________	-1.09	116993	107654	unknown	unknown
YNL216W	RAP1______	-1.29	208530	161392	transcription	transcriptional repressor and activator
YOL120C	RPL18A____	-1.30	14182354	10907648	protein synthesis	ribosomal protein L18A
YOR332W	VMA4______	+1.15	3476605	4004344	vacuolar acidification	vacuolar H+-ATPase V1 domain 27 KD subunit
YPR027C	__________	-1.20	237977	198130	unknown	unknown; similar to Ynl019p and Ynl033p
YBR007C	__________	-1.00	212553	212330	unknown	unknown
YCL028W	RNQ1______	-1.14	846196	742868	unknown	unknown; "transferable epigenetic modifier"
YDL124W	__________	+2.09	606463	1267562	unknown	unknown
YEL027W	CUP5______	-1.01	3852588	3798448	ATP synthesis	vacuolar ATP synthase subunit
YFR044C	__________	-1.21	1256159	1040728	unknown	unknown; similar to Ybr281p
YGR045C	__________	+1.01	114983	116289	unknown	unknown
YHR062C	RPP1______	-1.16	465645	400248	rRNA and tRNA processing	RNase P and RNase MRP subunit
YIR032C	DAL3______	-1.04	115825	111585	purine metabolism	ureidoglycolate hydrolase
YJR092W	BUD4______	-1.04	124156	119194	bud site selection, axial	unknown
YKR088C	__________	+1.07	484361	520283	unknown	unknown
YLR243W	__________	+1.03	542991	557096	unknown	unknown
YML112W	CTK3______	-1.03	376521	366579	cell cycle (putative)	protein kinase subunit
YNL028W	__________	-1.02	117729	115874	unknown	unknown
YNR067C	__________	+1.12	382700	427447	unknown	unknown
YOR144C	EFD1______	-1.08	146817	135547	recombination (putative)	unknown
YPL122C	TFB2______	-1.11	326977	294587	transcription	TFIIH 55 kD subunit
YAL038W	CDC19_____	-1.23	12224286	9978894	glycolysis	pyruvate kinase
YBR205W	KTR3______	-1.30	704931	541828	protein glycosylation	putative alpha-1,2-mannosyltransferase
YDR076W	RAD55_____	-1.40	208143	149021	DNA repair and recombination	RecA homolog
YDR443C	SSN2______	+1.00	1119434	1122739	transcription	RNA polymerase II mediator subunit
YER137C	__________	-1.18	130126	109845	unknown	unknown
YGL136C	__________	+1.17	294943	345526	unknown	unknown; similar to E. coli ftsJ protein
YGR243W	__________	+1.10	341411	374476	unknown	unknown
YIL039W	__________	+1.12	585932	655865	unknown	unknown
YJL137C	GLG2______	+1.17	182699	212939	glycogen metabolism	glycogen synthesis initiator
YKL133C	__________	+1.28	127706	164002	unknown	unknown
YLR067C	PET309____	+1.05	98837	103951	RNA processing	COX1 mRNA stability
YLR437C	__________	-1.19	1078454	907239	unknown	unknown
YMR172W	HOT1______	-1.06	186354	176592	osmotic stress response (putative)	unknown; nuclear protein; similar to Msn1p
YNL228W	__________	-1.07	431994	402253	unknown	unknown
YOL132W	__________	-1.11	138228	125066	unknown	unknown; similar to glycophospholipid-anchored surface glycoprotein GAS1
YPR039W	__________	-1.31	183895	140358	unknown	unknown
YBR017C	KAP104____	-1.24	263482	213147	nuclear protein targeting	beta-karyopherin
YCL040W	GLK1______	+1.87	237852	443611	glycolysis	glucokinase
YDL134C	PPH21_____	+1.09	993518	1084812	cell cycle	protein phosphatase 2A
YDR259C	YAP6______	+1.02	149316	152454	salt tolerance	basic leu zipper transcription factor
YEL039C	CYC7______	-1.08	528773	490385	respiration	cytochrome c (isoform 2)
YFR056C	__________	-1.19	132309	111486	unknown	unknown
YGR057C	LST7______	+1.04	122789	128129	secretion	unknown; post-Golgi
YHR072W	ERG7______	-1.05	306394	292548	sterol metabolism	lanosterol synthase
YIR044C	__________	-1.12	164018	145895	unknown	unknown
YJR103W	URA8______	-1.18	339482	287418	pyrimidine biosynthesis	CTP synthase
YKR100C	__________	-1.26	358952	283918	unknown	unknown
YLR255C	__________	+1.14	107081	122209	unknown	unknown
YML123C	PHO84_____	+1.27	2488620	3168820	transport	inorganic phosphate permease
YNL038W	__________	+1.12	403338	449918	unknown	unknown
YOR156C	NFI1______	-1.10	345389	312609	unknown	interacts with Cdc12p in 2-hybrid assay
YPL134C	ODC1______	-1.08	190277	175634	unknown	unknown; similar to mitochondrial ADP/ATP carrier proteins
YAL049C	__________	+1.12	477721	533741	unknown	unknown
YBR217W	APG12_____	+1.02	220896	224732	autophagy	unknown
YDR088C	SLU7______	-1.01	258160	256807	mRNA splicing	3' splice site selection
YDR455C	__________	-1.18	129838	109886	unknown	unknown
YER146W	LSM5______	+1.02	743854	760884	mRNA splicing (putative)	unknown; similar to snRNA-associated protein
YGL148W	ARO2______	-1.02	1775196	1738966	aromatic amino acid biosynthesis	chorismate synthase
YGR255C	COQ6______	+1.17	341915	401036	ubiquinone biosynthesis	monooxygenase
YIL051C	MMD1______	+1.20	4662069	5610520	maintenance of mitochondrial DNA	unknown
YJL149W	__________	+1.18	236630	278276	unknown	unknown
YKL145W	RPT1______	-1.15	971375	844118	protein degradation, ubiquitin-mediated	26S proteasome subunit
YLR079W	SIC1______	+1.14	445640	509990	cell cycle	Cdc28p-Clb5 protein kinase inhibitor
YLR449W	FPR4______	-1.39	2308240	1660366	protein folding (putative)	similar to peptidyl-prolyl cis-trans isomerase
YMR182C	RGM1______	-1.27	304354	239097	transcription	putative repressor
YNL240C	NAR1______	-1.25	232743	185897	nuclear organization and biogenesis (putative)	unknown; similar to human Narf

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOL144W	NOP8______	-1.18	565831	479859	ribosome biogenesis (putative)	unknown; nucleolar protein
YOR354C	__________	-1.16	364207	313744	unknown	unknown
YPR051W	MAK3______	+1.21	463963	559643	viral propagation	L-A virus GAG protein N-acetyltransferase
YBR029C	CDS1______	-1.21	137321	113268	lipid metabolism	CDP-diacylglycerol synthase
YCL052C	PBN1______	+1.11	325084	359880	protein degradation	protease B
YDL146W	__________	-1.02	146838	144092	unknown	unknown
YDR267C	__________	-1.22	393551	322079	unknown	unknown; similar to Sec13p and other proteins with WD
YEL051W	VMA8______	+1.09	1880394	2044206	vacuolar acidification	vacuolar H+-ATPase V1 domain D subunit
YGR069W	__________	-1.13	490024	431961	unknown	unknown
YHR083W	__________	+1.01	606743	614818	unknown	unknown
YJR115W	__________	+1.06	604112	642538	unknown	unknown
YLR263W	RED1______	-1.04	155354	149395	meiosis, synapsis	synaptonemal complex component (putative)
YMR002W	__________	+1.21	1278734	1548716	unknown	unknown
YNL050C	__________	+1.03	498030	513745	unknown	unknown
YOR168W	GLN4______	-1.40	606220	431664	protein synthesis	tRNA synthetase, glutaminyl
YPL146C	__________	-1.37	926735	673992	unknown	unknown
YAL063C	FLO9______	+1.07	295908	316645	flocculation	cell wall protein
YBR229C	ROT2______	-1.11	228310	205127	cytoskeleton	glucosidase II
YDR467C	__________	+1.12	238300	267223	unknown	unknown
YER157W	SEC34_____	-1.08	256909	238840	secretion	Golgi protein retention
YGL160W	__________	+1.01	166742	167795	unknown	unknown
YGR267C	FOL2______	-1.22	891756	733649	folate biosynthesis	GTP cyclohydrolase I
YIL063C	YRB2______	-1.09	731785	672188	nuclear export	Ran-GTPase-binding protein
YJL161W	__________	+1.47	136955	200713	unknown	unknown
YKL157W	APE2______	-1.09	359852	330762	protein degradation	aminopeptidase yscII
YLR091W	__________	-1.05	124646	118498	unknown	unknown
YLR461W	PAU4______	+1.03	319917	328591	unknown	unknown; seripauperin family
YNL252C	MRPL17____	-1.01	337535	335586	protein synthesis	ribosomal protein, mitochondrial L17
YOL156W	HXT11_____	-1.17	195588	166527	transport	hexose permease
YOR366W	__________	-1.01	165927	164730	unknown	unknown
YPR063C	__________	+1.09	613689	666642	unknown	unknown
YBR041W	FAT1______	-1.07	126270	118223	transport	long-chain fatty acid transporter
YCL064C	CHA1______	-1.05	1961435	1868128	hydroxy amino acid metabolism	L-serine/L-threonine deaminase
YDL158C	__________	-1.08	132863	122761	unknown	unknown
YDR279W	__________	+1.02	267568	273532	unknown	unknown
YEL062W	NPR2______	+1.04	146920	152754	nitrogen transport	transcription factor
YGR081C	__________	-1.07	701481	653131	unknown	unknown; similar to chicken myosin heavy chain PIR:A29320
YHR095W	__________	+1.04	302394	315513	unknown	unknown
YJR127C	ZMS1______	+1.11	520595	577624	unknown	unknown; similar to Adr1p and Yml081p
YLR275W	SMD2______	+1.09	294058	321302	mRNA splicing	U1 snRNP protein
YMR014W	__________	-1.32	724632	548388	unknown	unknown
YNL060C	__________	+1.02	1037662	1060183
YOR180C	DCI1______	-1.04	160282	154519	fatty acid metabolism	delta(3,5)-delta(2,4)-dienoyl-CoA isomerase
YPL158C	__________	-1.01	288118	285456	unknown	unknown
YAR009C	__________	-1.01	106435	105559	unknown	unknown
YBR241C	__________	+1.07	130879	140388	unknown	unknown; similar to sugar permeases
YDR110W	FOB1______	-1.18	213519	181531	DNA replication(putative)	fork blocking protein
YDR479C	__________	+1.13	242705	274165	unknown	unknown
YER166W	__________	-1.06	116108	109276	unknown	unknown; similar to members of the Drs2p family of P-type
YGL172W	NUP49_____	-1.14	257629	226208	nuclear protein targeting	nuclear pore protein
YGR279C	SCW4______	+1.08	5617815	6040005	cell wall biogenesis	glucanase (putative)
YIL072W	HOP1______	-1.30	213298	163681	meiosis, synapsis	DNA binding protein
YJL173C	RFA3______	+1.18	635814	750279	DNA replication	replication factor A, 13 kD subunit
YKL169C	__________	+1.04	372487	389041	unknown	unknown
YLR103C	CDC45_____	-1.07	200946	187438	DNA replication	pre-replicative complex subunit (putative)
YMR205C	PFK2______	-1.49	1129424	757929	glycolysis	phosphofructokinase
YNL264C	PDR17_____	+1.05	340422	358036	drug resistance	unknown
YOR002W	ALG6______	-1.12	719954	641447	protein glycosylation	glucosyltransferase
YOR378W	__________	-1.06	155028	146627	unknown	unknown; similar to members of major facilitator superfamily
YPR075C	OPY2______	+1.06	453600	482240	signaling (putative)	pheromone pathway
YBR053C	__________	+1.33	242386	321702	unknown	unknown; similar to rat calcium-binding protein regucalcin
YCLX03C	__________	+1.02	100418	102070
YDL170W	UGA3______	+1.00	187389	188289	transcription	activator of GABA catabolic genes
YDR291W	__________	-1.09	150970	138949	unknown	unknown; similar to Sgs1p and other DNA helicases
YEL074W	__________	-1.04	255836	245539	unknown	unknown
YGR093W	__________	-1.10	401325	365761	unknown	unknown
YHR107C	CDC12_____	-1.16	1093025	943094	cytokinesis	septin
YJR139C	HOM6______	+1.01	2361807	2380058	methionine and threonine biosynthesis	homoserine dehydrogenase
YLR287C	__________	-1.12	415194	372005	unknown	unknown
YMR026C	PEX12_____	+1.00	337511	339165	peroxisome biogenesis	integral membrane protein
YNL072W	RNH35_____	-1.06	314934	297322	DNA replication (putative)	ribonuclease H
YOR192C	__________	-1.08	240315	221805	unknown	putative thiamine transporter
YPL170W	__________	+1.03	121200	124361	unknown	unknown
YAR031W	__________	+1.07	209478	223337	unknown	unknown; similar to subtelomerically-encoded proteins
YBR253W	SRB6______	+1.32	361646	478017	transcription	RNA polymerase mediator subunit
YDR122W	KIN1______	+1.04	196049	204324	unknown	protein kinase
YDR491C	__________	+1.03	141378	145623	unknown	unknown; similar to Hrd312p
YER177W	BMH1______	+1.04	5218475	5406686	unknown	unknown; similar to mammalian 14-3-3 proteins
YGL184C	STR3______	+1.04	232008	240383	methionine biosynthesis	cystathionine beta-lyase
YGR291C	__________	+1.05	120309	126448	unknown	unknown
YIL083C	__________	+1.03	368104	379458	unknown	unknown
YJL185C	__________	+1.08	255258	274806	unknown	unknown
YKL181W	PRS1______	-1.14	2252167	1980006	purine, pyrimidine, tryptophan and histidine biosynthesis	phosphoribosylpyrophosphate synthetase
YLR115W	CFT2______	-1.09	214588	196936	mRNA 3'-end processing	cleavage/polyadenylation factor CF II component
YMR217W	GUA1______	-1.63	5322860	3270913	purine metabolism	GMP synthase
YNL276C	__________	+1.21	176589	214518	unknown	unknown
YOR014W	RTS1______	-1.13	429995	381392	stress response	protein phosphatase 2A B-type regulatory subunit
YOR390W	__________	-1.32	485198	367483	unknown	unknown
YPR087W	__________	+1.00	1700578	1708659	unknown	unknown
YBR065C	ECM2______	-1.09	140033	127886	cell wall biogenesis and mRNA splicing (putative)	unknown
YCR003W	MRPL32____	+1.15	132392	152673	protein synthesis	ribosomal protein, mitochondrial L32
YDL182W	LYS20_____	-1.22	3248643	2668709	lysine biosynthesis	homocitrate synthase
YDR303C	__________	-1.16	311052	269069	unknown	unknown; similar to transcription factors
YER007W	PAC2______	+1.02	180078	184304	mitosis	unknown; microtubule stability
YGR105W	VMA21_____	+1.17	362581	423815	vacuolar acidification	vacuolar H+-ATPase assembly protein
YHR119W	SET1______	+1.12	864797	969187	transcription	trithorax protein family
YJR151C	__________	-1.07	196100	183285	unknown	unknown
YLR298C	YHC1______	+1.05	277228	291543	mRNA splicing	U1 snRNP protein
YMR037C	MSN2______	-1.12	210951	188027	stress response	transcriptional activator
YNL084C	END3______	-1.11	646458	580628	endocytosis	actin cytoskeleton regulatory complex component

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOR202W	HIS3______	-1.34	809306	606189	histidine biosynthesis	imidazoleglycerol-phosphate dehydratase
YPL182C	__________	-1.07	157170	146727	unknown	unknown
YBL004W	__________	-1.51	159199	105117	unknown	unknown; major facilitator superfamily
YBR265W	TSC10_____	-1.25	438511	350218	sphingolipid biosynthesis	3-ketosphinganine reductase
YDL004W	ATP16_____	+1.44	677932	977943	ATP synthesis	F1F0-ATPase subunit
YDR134C	__________	+1.20	15706281	18798179	unknown	unknown
YDR503C	LPP1______	+1.03	299519	308515	phospholipid metabolism	lipid phosphate phosphatase
YFL002C	SPB4______	-1.12	457017	407163	rRNA processing, 25S	RNA helicase
YGL196W	__________	+1.28	294026	374913	unknown	unknown
YHL003C	LAG1______	-1.18	400540	338773	aging	unknown
YIL095W	PRK1______	+1.03	377911	390757	unknown	protein kinase
YJL197W	UBP12_____	-1.04	159968	153571	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YKL193C	SDS22_____	+1.24	252457	314124	glucose repression	Glc7p regulatory subunit
YLR127C	APC2______	-1.02	131507	128509	mitosis	anaphase promoting complex subunit
YML004C	GLO1______	+1.23	767872	944995	amino acid metabolism	glyoxalase I
YMR229C	RRP5______	-1.27	1949532	1537409	rRNA processing	unknown; required for pre-rRNA cleavage
YNL286W	CUS2______	-1.06	292412	276683	mRNA splicing, putative	unknown
YOR026W	BUB3______	-1.06	394492	372750	cell cycle, checkpoint	unknown
YPL004C	__________	+1.11	928599	1032194	unknown	unknown; similar to tropomyosin
YPR099C	__________	-1.05	802483	762601	unknown	unknown
YBR077C	__________	-1.00	200609	199767	unknown	unknown
YCR015C	__________	-1.02	130988	129052	unknown	unknown
YDL194W	SNF3______	-1.08	109832	102009	transport	glucose permease
YDR315C	IPK1______	+1.16	132831	153815	signaling (putative)	inositol(1,4,5)P3 6-kinase
YER017C	AFG3______	-1.21	213245	175722	protein degradation	mitochondrial metalloprotease
YGL004C	__________	+1.08	100522	108694	unknown	unknown
YGR115C	__________	-1.08	188599	174753	unknown	unknown; similar to Sly41p, questionable ORF
YHR131C	__________	+1.03	444449	459959	unknown	unknown
YJL004C	SYS1______	+1.11	334042	370718	secretion (putative)	unknown; overexpression suppresse mutation in ypt6
YKL004W	AUR1______	-1.16	1242054	1070375	sphingolipid metabolism	phosphatidylinositol:ceramide phosphoinositol transferase
YLL004W	ORC3______	-1.01	156880	155832	DNA replication	origin recognition complex, 62 kDa subunit
YLR310C	CDC25_____	-1.07	511018	476295	signaling	GDP/GTP exchange factor for Ras1p and Ras2p
YMR048W	__________	-1.13	199856	176713	unknown	unknown
YNL096C	RPS7B_____	-1.02	8916810	8705716	protein synthesis	ribosomal protein S7B
YOL004W	SIN3______	-1.10	374934	340039	transcription	transcriptional regulator
YOR214C	__________	-1.14	118939	104442	unknown	unknown
YPL193W	RSA1______	-1.36	237620	174137	ribosome biogenesis (putative)	unknown
YAR060C	__________	-1.30	214160	165189	unknown	identical to Yhr2p
YBL014C	RRN6______	-1.23	149451	121558	transcription	component of rDNA transcription factor complex
YBR277C	__________	-1.30	153003	117590	unknown	unknown
YDL016C	__________	-1.02	396911	388249	unknown	unknown
YDR146C	SWI5______	-1.20	152900	127551	cell cycle	transcription factor, regulates HO
YDR515W	SLF1______	-1.17	241760	205842	Cu2+ ion homeostasis	CuS biomineralization
YGL208W	SIP2______	+1.15	206640	238255	transcription	component of Snf1 protein complex
YHL012W	__________	+1.14	161803	184789	unknown	unknown; similar to UTP glucose-1-phosphate
YIL106W	MOB1______	+1.10	354209	390290	mitosis	unknown; binds Mps1p and Dbf2p
YJL209W	CBP1______	-1.01	260419	257992	mRNA stability, COB mRNA	unknown
YKL205W	LOS1______	-1.10	917370	837098	tRNA splicing	nuclear pore protein
YLR139C	SLS1______	+1.06	163857	173312	mitochondrial metabolism	integral membrane protein
YML013W	__________	-1.07	144121	135085	unknown	unknown
YMR241W	YHM2______	-1.05	622755	592727	unknown	suppresses HM mutant
YNL298W	CLA4______	+1.01	901536	908770	cytokinesis	protein kinase
YOR038C	HIR2______	-1.06	153221	144085	transcription	histone transcription inhibitor
YPL016W	SWI1______	-1.10	110634	100515	transcription	component of SWI/SNF global activator complex
YPR111W	DBF20_____	-1.10	150133	136360	cell cycle	M phase; protein kinase
YBR088C	POL30_____	-1.07	370876	347783	DNA replication	DNA polymerase processivity factor
YCR025C	__________	-1.03	131804	128240	unknown	unknown
YDL206W	__________	-1.05	140487	133245	unknown	unknown; similar to transporter proteins
YDR325W	YCG1______	-1.32	211427	160707	mitosis, chromosome condensation (putative)	unknown; high copy suppressor of brn1 mutation
YER028C	__________	-1.03	167327	161757	unknown	unknown; similar to Mig2p
YGL016W	KAP122____	-1.33	327013	246465	drug resistance	karyopherin-beta family protein
YGR127W	__________	-1.02	289988	284511	unknown	unknown; similar to mouse T10 protein PIR:S37448
YHR141C	RPL42B____	+1.09	13368650	14545172	protein synthesis	ribosomal protein L42B
YJL016W	__________	+1.23	303777	372294	unknown	unknown
YKL015W	PUT3______	-1.10	280199	253582	transcription	positive regulator of PUT genes
YLL016W	SDC25_____	+1.01	165884	167189	signaling (putative)	GDP/GTP exchange factor for Ras
YLR321C	SFH1______	-1.27	378799	298658	chromatin structure	chromatin remodeling complex subunit
YMR058W	FET3______	-1.84	574317	312283	transport	cell surface ferroxidase
YNL108C	__________	-1.13	555138	492389	unknown	unknown
YOL016C	CMK2______	+1.02	778326	796632	signaling	calmodulin-dependent protein kinase
YOR226C	ISU2______	-1.12	378202	337295	iron homeostasis	unknown; similar to iron-sulfur cluster protein nifU
YPL205C	__________	-1.49	179471	120686	unknown	unknown
YBL026W	LSM2______	+1.09	452834	493281	mRNA splicing	core snRNP protein
YBR289W	SNF5______	-1.04	3203810	3089541	transcription	component of SWI/SNF global activator complex
YDL028C	MPS1______	-1.13	214457	190222	mitosis, checkpoint	protein kinase
YDR158W	HOM2______	-1.66	1346868	811275	threonine and methionine biosynthesis	aspartate-semialdehyde dehydrogenase
YDR527W	__________	-1.35	276611	204241	unknown	unknown
YGL220W	__________	+1.14	683642	778368	unknown	unknown; similar to Vibrio alginolyticus bolA protein
YHL024W	RIM4______	+1.02	137246	139906	sporulation (putative)	unknown; N-terminus has putative RNA binding domain
YIL118W	RHO3______	+1.00	102910	103220	cytoskeleton	GTP-binding protein, rho family
YJL221C	FSP2______	+1.10	154551	169579	unknown	unknown; similar to maltase
YKL217W	JEN1______	+1.07	112146	119872	transport	lactate transporter
YLR151C	PCD1______	+1.06	121630	128419	unknown	nudix hydrolase family
YMR253C	__________	-1.05	105750	100346	unknown	major facilitator superfamily
YNL310C	__________	+1.05	394606	415706	unknown	unknown
YOR050C	__________	-1.06	187094	176801	unknown	unknown
YPL028W	ERG10_____	+1.10	2550322	2800940	sterol metabolism	acetoacetyl CoA thiolase
YPR123C	__________	-1.25	161856	129504	unknown	unknown
YBR099C	__________	-1.01	143576	142183	unknown	unknown
YCR036W	RBK1______	+1.04	127967	132986	ribose metabolism	ribokinase
YDL218W	__________	-1.24	162789	131344	unknown	unknown
YDR337W	MRPS28____	-1.11	396695	357677	protein synthesis	ribosomal protein, mitochondrial S28
YER039C	HVG1______	-1.11	143398	129026	protein glycosylation (putative)	nucleotide sugar transporter (putative)
YGL028C	SCW11_____	-1.09	729422	668749	cell wall biogenesis	glucanase (putative)
YGR139W	__________	+1.00	165380	165609	unknown	unknown
YHR152W	SPO12_____	+1.28	531046	681410	meiosis; mitotic cell cycle	unknown
YJL028W	__________	-1.32	229775	173676	unknown	unknown
YKL027W	__________	-1.05	516023	492366	unknown	unknown; similar to E. coli molybdopterin-converting factor
YLL028W	TPO1______	-1.30	317361	243576	transport	polyamine transport protein
YLR333C	RPS25B____	+1.16	14935435	17346778	protein synthesis	ribosomal protein S25B

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YMR070W	MOT3______	+1.02	376103	382798	mating	transcriptional regulator of pheremone-responsive genes
YNL120C	__________	-1.36	207072	152430	unknown	unknown
YOL028C	YAP7______	-1.34	240639	179102	transcription	basic leucine zipper transcription factor
YOR238W	__________	+1.16	365472	423413	unknown	unknown
YPL217C	BMS1______	-1.32	1367200	1037530	unknown	unknown; essential
YBL038W	MRPL16____	-1.09	108836	99848	protein synthesis	ribosomal protein, mitochondrial L16
YBR301W	__________	+1.03	263658	270261	unknown	unknown; similar to Ykl224p and other members of the PAU1
YDL040C	NAT1______	-1.22	355294	291319	protein processing	protein N-acetyltransferase subunit
YDR170C	SEC7______	-1.34	660651	493553	secretion	vesicle coat component
YDR539W	__________	-1.12	333023	297080	unknown	unknown
YFL033C	RIM15_____	-1.06	434500	411547	meiosis	protein kinase
YGL231C	__________	+1.29	713295	920890	unknown	unknown
YHL035C	__________	-1.13	1851332	1644334	unknown	unknown; ATP-binding cassette (ABC) superfamily
YIL130W	__________	-1.67	1014173	605827	unknown	unknown; similar to transcription factors
YJR009C	TDH2______	+1.22	15743220	19165954	glycolysis	glyceraldehyde-3-phosphate dehydrogenase 2
YKR004C	ECM9______	-1.18	749849	635674	cell wall biogenesis	unknown
YLR161W	__________	+1.69	498997	841657	unknown	unknown
YML035C	AMD1______	-1.32	336023	254865	protein glycosylation	alpha-mannosidase, putative
YMR265C	__________	-1.13	311563	276201	unknown	unknown
YNL322C	KRE1______	+1.12	836771	940754	cell wall biogenesis	beta-1,6-glucan assembly
YOR062C	__________	-1.06	136660	129074	unknown	unknown
YPL040C	ISM1______	-1.23	252869	206378	protein synthesis	tRNA synthetase, mitochondrial, isoleucyl
YPR135W	CTF4______	-1.07	115835	108532	DNA replication	polymerase alpha binding protein
YBR110W	ALG1______	+1.11	312196	345551	protein glycosylation	beta-1,4-mannosyltransferase
YCR048W	ARE1______	-1.24	131188	105844	sterol metabolism	acyl-CoA sterol acyltransferase
YDL230W	PTP1______	-1.04	213904	206528	unknown	protein phosphatase
YDR349C	YPS7______	-1.05	460727	440562	protein degradation	GPI-anchored aspartic protease
YER049W	__________	-1.16	554006	476626	unknown	unknown
YGL040C	HEM2______	-1.42	555887	391914	heme biosynthesis	porphobilinogen synthase
YGR151C	__________	+1.14	261694	298815	unknown	unknown
YHR164C	DNA2______	+1.10	314324	346585	DNA replication	DNA helicase
YJL041W	NSP1______	-1.33	685571	515746	nuclear protein targeting	nuclear pore protein
YKL038W	RGT1______	-1.09	133926	123029	(glucose) transport	transcriptional regulator of glucose transporters
YLL040C	VPS13_____	-1.05	156889	149727	vacuolar protein targeting	component of peripheral membrane protein complex
YLR345W	__________	+1.36	164662	223262	unknown	unknown
YMR081C	ISF1______	-1.01	150020	148212	RNA splicing, mitochondrial	interacts with Nam7p
YNL132W	__________	-1.50	509459	339221	unknown	unknown; similar to Achlya ambisexualis antheridiol steroid
YOL040C	RPS15_____	+1.19	15769014	18776967	protein synthesis	ribosomal protein S15
YOR250C	CLP1______	-1.03	320477	311063	mRNA 3'-end processing	cleavage/polyadenylation factor CF IA component
YPL229W	__________	+1.16	849592	981679	unknown	unknown
YBL050W	SEC17_____	+1.03	612507	630162	secretion	SNAP; vesicle fusion
YDL052C	SLC1______	-1.25	297595	237339	phospholipid metabolism	fatty acyltransferase
YFL043C	__________	+1.15	216867	248702	unknown	unknown
YGL243W	TAD1______	+1.09	219898	240681	tRNA processing	tRNA-specific adenosine deaminase
YIL142W	CCT2______	-1.22	1239690	1013680	protein folding	cytoplasmic chaperonin complex
YJR020W	__________	+1.05	114570	120668	unknown	unknown
YKR016W	__________	-1.03	374523	363839	unknown	unknown
YLR173W	__________	+1.10	101930	111989	unknown	unknown
YML045W	__________	-1.24	3171099	2557950	unknown	unknown
YMR277W	FCP1______	-1.19	406985	342842	transcription	TFIIF interacting component of CTD phosphatase
YNL334C	SNO2______	+1.06	193800	206162	unknown	unknown; induced in stationary phase
YOR074C	CDC21_____	-1.09	499335	459074	DNA replication	thymidylate synthase
YPL052W	__________	+1.28	262333	336097	unknown	unknown
YPR145W	ASN1______	-1.37	1793353	1306625	asparagine biosynthesis	asparagine synthetase
YBR122C	MRPL36____	-1.04	315780	302546	protein synthesis	ribosomal protein, mitochondrial L36
YCR060W	__________	+1.10	305830	336113	unknown	unknown; similar to stress inducible protein Sti1p, has
YDL242W	__________	-1.10	113308	103186	unknown	unknown
YDR361C	__________	-1.33	890453	671044	unknown	unknown
YER060W	FCY21_____	-1.15	253041	220512	transport	purine-cytosine permease
YGL052W	__________	+1.01	191568	192576	unknown	unknown
YHR176W	__________	+1.17	116806	136778	unknown	unknown; similar to flavin-containing monooxygenases
YJL053W	PEP8______	+1.05	371753	390836	vacuolar protein targeting	vacuolar peripheral memebrane protein
YKL050C	__________	+1.13	103152	116580	unknown	unknown
YLL052C	AQY2______	-1.48	1534743	1039200	transport, water	aquaporin (putative)
YLR357W	RSC2______	-1.16	151829	130872	chromatin structure	chromatin remodeling complex subunit
YMR092C	AIP1______	-1.31	174643	133395	cytoskeleton	actin cortical patch component
YNL144C	__________	-1.10	165144	149977	unknown	unknown
YOL052C	SPE2______	-1.16	501520	431572	polyamine metabolism	S-adenosylmethionine decarboxylase
YOR262W	__________	-1.12	430786	384727	unknown	unknown
YPL241C	CIN2______	+1.03	268937	277525	mitosis, chromosome segregation	unknown
YBL062W	__________	+1.32	303971	401704	unknown	unknown
YDL064W	UBC9______	+1.10	738233	810557	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YDR191W	HST4______	-1.03	160729	156541	silencing (telomere)	unknown; similar to nuclear lamins
YFL055W	AGP3______	-1.05	128233	121921	transport	general amino acid permease
YGL255W	ZRT1______	-1.27	326359	256264	transport	high-affinity zinc transporter
YHR006W	STP2______	+1.33	216864	289057	tRNA splicing	unknown
YIL154C	(IMP2)____	+1.03	472258	486797	stress response	transcriptional repressor
YJR031C	GEA1______	-1.00	529749	528382	secretion	GDP/GTP exchange factor for ARF
YKR028W	SAP190____	-1.10	986506	900550	cell cycle	Sit4p-associated protein
YLR185W	RPL37A____	-1.06	9653563	9080983	protein synthesis	ribosomal protein L37A
YMR289W	__________	-1.07	233157	218323	unknown	unknown
YNR007C	AUT1______	+1.04	208617	217325	autophagy	unknown
YOR086C	__________	+1.01	775202	782070	unknown	unknown
YPL062W	__________	-1.15	138418	120806	unknown	unknown
YPR157W	__________	+1.29	174589	225229	unknown	unknown
YBR134W	__________	-1.01	129016	127571	unknown	unknown
YCR071C	IMG2______	+1.08	257823	279561	mitochondrial DNA maintenance	unknown
YDR006C	SOK1______	-1.12	285016	254543	unknown	suppressor of a cAMP-dependent protein kinase mutant
YDR371W	__________	+1.07	238945	255201	unknown	unknown; similar to chitinases
YGL064C	__________	-1.01	187129	185848	unknown	unknown
YGR171C	MSM1______	+1.00	244354	245044	protein synthesis	tRNA synthetase, mitochondrial, methionyl
YHR188C	__________	-1.04	573590	550107	unknown	unknown
YJL065C	__________	+1.03	402319	414861	unknown	unknown; similar to DNA polymerase epsilon subunit c
YKL062W	MSN4______	+1.08	187642	202531	transcription	transcriptional activator with Snf1p
YLL064C	__________	+1.16	332328	384394	unknown	unknown; similar to members of the PAU1 family
YLR369W	SSQ1______	-1.05	263127	249932	DNA replication (mitochondrial)	mitochondrial HSP70
YMR104C	YPK2______	+1.01	142892	144386	unknown	protein kinase
YNL156C	__________	+1.25	479012	597081	unknown	unknown
YOL062C	APM4______	-1.08	547119	508414	secretion	vesicle coat component
YOR274W	MOD5______	+1.04	268286	278279	tRNA processing	tRNA isopentenyltransferase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YPL252C	YAH1______	-1.13	792420	702909	unknown	unknown; similar to adrenodoxin and ferrodoxin
YMR319C	FET4______	-1.35	377570	279276	transport	iron transporter
YBL074C	AAR2______	-1.09	132124	120854	mRNA splicing, MATa1	unknown
YDL076C	__________	+1.04	288335	299162	unknown	unknown
YDR203W	__________	-1.10	159947	145115	unknown	unknown
YFL067W	__________	-2.71	512636	189491	unknown	unknown; similar to periodic clock protein
YGR004W	__________	-1.18	185464	157160	unknown	unknown
YHR018C	ARG4______	-1.14	575719	506530	arginine biosynthesis	argininosuccinate lyase
YIL165C	__________	+1.07	209148	222905	unknown	unknown; similar to nitrilases, putative pseudogene
YJR043C	POL32_____	-1.08	414776	384630	DNA replication	polymerase delta 55 kD subunit
YKR040C	__________	-1.10	479008	436882	unknown	unknown
YLR197W	SIK1______	-1.27	3799971	2981228	rRNA processing	nucleolar protein
YMR299C	__________	+1.10	221417	244362	unknown	unknown
YNR019W	ARE2______	-1.07	101890	95455	sterol metabolism	acyl-CoA sterol acyltransferase
YOR098C	NUP1______	-1.28	519379	405973	nuclear protein targeting	nuclear pore protein
YPL074W	YTA6______	+1.11	125728	139721	unknown	unknown; AAA ATPase family
YPR165W	RHO1______	+1.29	2828900	3648548	signaling	GTP-binding protein, rho family
YBR146W	MRPS9_____	-1.07	296885	278166	protein synthesis	ribosomal protein, mitochondrial S9
YCR084C	TUP1______	-1.27	645442	508196	transcription	general repressor
YDR018C	__________	-1.13	141336	125546	unknown	unknown; similar to Ybr042p
YDR383C	__________	+1.10	236166	259257	unknown	unknown
YER080W	__________	-1.03	447985	436220	unknown	unknown
YGL076C	RPL7A_____	-1.35	3555408	2642279	protein synthesis	ribosomal protein L7A
YGR183C	QCR9______	+1.35	754321	1014930	oxidative phosphorylation	ubiquinol cytochrome-c reductase subunit 9
YHR200W	RPN10_____	+1.02	1519366	1555661	protein degradation	26S proteasome subunit
YJL077C	ICS3______	-1.10	362986	328624	Cu2+ ion homeostasis (putative)	unknown
YKL074C	MUD2______	-1.18	264822	223756	mRNA splicing	commitment complex component
YLR009W	__________	-1.12	2264546	2021193	protein synthesis	ribosomal protein L24B (putative)
YLR381W	__________	+1.02	250595	255230	unknown	unknown
YNL168C	__________	+1.11	327698	364531	unknown	unknown; similar to E. coli hpcE gene product which is
YOL074C	__________	-1.19	150306	126384
YOR286W	__________	-1.01	726051	720024	unknown	unknown; similar to Drosophila melanogaster heat shock
YPL262W	FUM1______	+1.02	878726	899662	TCA cycle	fumarate hydratase
YBL086C	__________	-1.05	205545	196284	unknown	unknown
YDL088C	ASM4______	-1.02	299711	295190	unknown	unknown; suppresses ts mutations in pol3
YDR211W	GCD6______	-1.13	359212	318968	protein synthesis	translation initiation factor eIF2b subunit
YFR011C	__________	+1.18	409907	484862	unknown	unknown
YGR016W	__________	+1.01	168178	169889	unknown	unknown
YHR029C	__________	+1.02	388024	395875	unknown	unknown; similar to thymidylate synthase in the N-terminal
YIL176C	__________	+1.12	438485	489654	unknown	unknown; similar to members of the PAU1 family
YJR055W	HIT1______	+1.04	246567	256867	unknown	required for growth at high temperature
YKR052C	MRS4______	-1.08	245780	227756	transport	mitochondrial carrier
YLR209C	__________	+1.18	510523	601710	unknown	unknown; similar to human purine nucleoside phosphorylase
YML079W	__________	+1.11	670685	747226	unknown	unknown
YMR309C	NIP1______	-1.49	831922	556769	nuclear protein targeting	unknown, similar to NSR1
YNR031C	SSK2______	-1.19	313339	263364	signaling, high osmolarity pathway	MAPKKK (mitogen-activated protein kinase kinase kinase)
YOR110W	TFC7______	-1.11	431103	388171	transcription	TFIIIC subunit
YPL086C	ELP3______	-1.50	700599	466859	chromatin structure	histone acetyltransferase complex subunit
YPR177C	__________	-1.24	185329	149840	unknown	unknown
YBR158W	CST13_____	+1.32	1060015	1401817	Cu2+ ion homeostasis (putative); chromosome stability	unknown; required for optimal growth
YCR095C	__________	+1.18	312790	368425	unknown	unknown
YDR030C	RAD28_____	+1.17	128855	150777	DNA repair	unknown
YDR395W	SXM1______	-1.21	459847	378974	mRNA export; nuclear protein targeting	karyopherin
YER091C	MET6______	+1.33	286027	381326	methionine biosynthesis	homocysteine methyltransferase
YGL088W	__________	+1.18	181600	214433	unknown	unknown; similar to Cyanophora paradoxa ribosomal protein
YGR195W	SKI6______	-1.10	787857	715542	rRNA processing	exoribonuclease
YHR212C	__________	-1.04	171318	165311	unknown	unknown; identical to Yar060p/Raa19p
YJL089W	SIP4______	-1.06	135060	127501	glucose derepression	transcription factor
YKL086W	__________	-1.07	151609	141446	unknown	unknown
YLR021W	__________	+1.04	446281	465586	unknown	unknown
YLR393W	ATP10_____	-1.09	112994	103562	ATP synthesis	F1F0 ATPase complex assembly
YMR127C	SAS2______	-1.06	260864	245010	silencing	zinc-finger protein
YNL180C	RHO5______	+1.09	628011	685045	signaling	Rho family GTPase
YOL086C	ADH1______	+1.21	15806622	19124397	glycolysis	alcohol dehydrogenase I
YOR298W	__________	-1.40	474903	340024	unknown	meiosis (putative)
YPL274W	SAM3______	-1.03	192740	186227	transport, amino acid	high affinity S-adenosylmethionine permease
YAL005C	SSA1______	-2.17	2308259	1064906	ER and mitochondrial translocation	cytosolic HSP70
YBR170C	NPL4______	-1.13	219983	195171	nuclear protein targeting	nuclear pore protein
YCR107W	AAD3______	-1.47	283974	193502	unknown	hypothetical aryl-alcohol dehydrogenase
YDR041W	__________	+1.01	356193	359470	protein synthesis	ribosomal protein, mitochondrial
YDR408C	ADE8______	-1.25	830937	662878	purine biosynthesis	phosphoribosylglycinamide formyltransferase
YER103W	SSA4______	-2.11	566462	268519	ER and mitochondrial translocation	cytosolic HSP70
YGL101W	__________	-1.15	482606	418023	unknown	unknown
YGR208W	SER2______	-1.18	867298	738059	glycine, serine, and threonine metabolism	phosphoserine phosphatase
YIL005W	__________	+1.07	273666	291820	unknown	unknown; similar to protein disulfide
YJL102W	MEF2______	+1.01	143130	144721	protein synthesis	translation elongation factor, mitochondrial
YKL098W	__________	+1.10	234551	258748	unknown	unknown
YLR034C	SMF3______	+1.05	301046	316298	transport (putative)	metal transporter (putative)
YLR406C	RPL31B____	-1.19	146914	123908	protein synthesis	ribosomal protein L31B
YMR139W	RIM11_____	+1.09	302724	331415	meiosis	protein kinase
YNL193W	__________	-1.00	204901	204790	unknown	unknown
YOL099C	__________	+1.08	319356	345112	unknown	unknown
YOR309C	__________	-1.17	5863098	5029677	unknown	unknown
YPR004C	__________	+1.02	678247	694893	unknown	unknown; similar to human electron transport flavoprotein
YBL099W	ATP1______	-1.13	709330	628061	ATP synthesis	mitochondrial F1F0-ATPase subunit
YCL004W	PGS1______	-1.11	145638	131092	phospholipid metabolism	phosphatidylglycerophosphate synthase
YDL101C	DUN1______	+1.00	227508	228248	DNA repair	DNA damage-responsive protein kinase
YDR224C	HTB1______	+1.06	5478888	5833396	chromatin structure	histone H2B
YEL005C	VAB2______	+1.04	208403	217769	vacuolar protein targeting (putative)	unknown; Vac8p binding protein
YFR024C	__________	-1.38	502510	362990	unknown	unknown
YHR041C	SRB2______	-1.03	262594	256019	transcription	RNA polymerase II mediator subunit
YIR012W	SQT1______	-1.20	815696	681642	ribosome biogenesis (putative)	unknown
YJR068W	RFC2______	-1.00	560714	559389	DNA replication	replication factor C 41 kD subunit
YKR065C	__________	+1.23	561463	691084	unknown	unknown
YLR222C	__________	-1.16	508916	440281	unknown	unknown
YML092C	PRE8______	+1.07	1181847	1263361	protein degradation	20S proteasome subunit Y7 (alpha2
YNL005C	MRP7______	-1.04	390930	374889	protein synthesis	ribosomal protein, mitochondrial large subunit
YNR044W	AGA1______	-1.48	503533	339177	mating	a-agglutinin anchor subunit
YOR123C	LEO1______	-1.37	430323	314319	unknown	unknown
YPL099C	__________	+1.03	274302	283015	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YPR190C	RPC82_____	-1.22	654771	538364	transcription	RNA polymerase III 82 kD subunit
YAL018C	__________	-1.06	95949	90646	unknown	unknown
YBR182C	SMP1______	-1.06	124128	116775	cell wall organization	MADS box transcription factor
YCRX12W	__________	-1.04	100572	97134
YDR053W	__________	-1.26	126070	99761	unknown	unknown
YDR420W	HKR1______	-1.11	293081	263040	cell wall biogenesis (putative)	unknown; cell surface protein
YER115C	SPR6______	-1.17	324688	277697	sporulation	unknown
YGL113W	__________	+1.08	166839	179358	unknown	unknown
YGR220C	MRPL9_____	+1.06	488404	517665	protein synthesis	ribosomal protein, mitochondrial L9
YIL016W	SNL1______	+1.13	667706	753855	nuclear protein targeting	nuclear pore protein (putative)
YJL114W	__________	+1.00	152956	153406	unknown	unknown
YKL110C	KTI12_____	-1.06	426322	403444	killer toxin resistance	unknown
YLR044C	PDC1______	-1.14	13370049	11757530	glycolysis	pyruvate decarboxylase
YLR416C	__________	-1.28	190637	148776	unknown	unknown
YMR151W	YIM2______	-1.25	153450	122852	unknown	unknown
YNL205C	__________	-1.21	168839	139394	unknown	unknown
YOL109W	ZEO1______	-1.05	8272421	7911289	zeocin resistance	unknown
YOR321W	PMT3______	-1.19	342934	288678	protein glycosylation	dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
YPR016C	TIF6______	-1.09	142436	131148	ribosome biogenesis (putative)	unknown; similar to human translation initiation factor 6 (eIF6)
YBL109W	__________	-1.10	299662	273096	unknown	unknown
YCL017C	NFS1______	-1.42	337116	237524	tRNA splicing	unknown
YDL113C	__________	-1.10	167110	151501	unknown	unknown
YEL017C	PMP2______	-1.52	1082625	710161	H+ homeostasis	regulates plasma membrane H+-ATPase
YFR034C	PHO4______	-1.31	187699	142780	phosphate signaling	transcription factor
YHR052W	__________	-1.33	688250	518841	unknown	unknown
YIR022W	SEC11_____	+1.04	514451	536603	secretion	signal peptidase subunit
YJR080C	__________	-1.07	190741	178346	unknown	unknown; similar to Arg8p
YKR077W	__________	+1.14	200950	228788	unknown	unknown
YLR232W	__________	-1.02	100155	98509	unknown	unknown
YNL017C	__________	-1.18	134155	114160	unknown	unknown
YNR056C	BIO5______	-1.16	134717	115969	biotin biosynthesis	transmembrane regulator of KAPA/DAPA transport
YOR135C	__________	-1.37	175639	128504	unknown	unknown
YPL111W	CAR1______	-1.04	350596	336029	arginine metabolism	arginase
YPR202W	__________	-1.18	340979	288346	unknown	unknown; similar to other subtelomerically-encoded proteins
YAL029C	MYO4______	-1.11	104164	93831	cell polarity	myosin; asymmetric HO expression
YBR194W	__________	+1.01	167053	168824	unknown	unknown
YDR065W	__________	-1.14	141406	124321	unknown	unknown
YDR432W	NPL3______	-1.79	388570	216780	mRNA export; protein import	nuclear shuttling protein
YER126C	__________	-1.12	350439	312248	unknown	unknown
YGL125W	MET13_____	+1.02	236413	240047	methionine metabolism	methylenetetrahydrofolate reductase, putative
YGR232W	NAS6______	+1.16	415423	480662	protein degradation (putative)	unknown; interacts with 26S proteasome
YIL028W	__________	-1.09	134114	122813	unknown	unknown
YJL126W	NIT2______	-1.05	185839	176601	unknown	nitrilase
YKL122C	SRP21_____	+1.12	650187	730683	secretion	signal recognition particle subunit
YLR056W	ERG3______	+1.00	2592753	2602123	sterol metabolism	C-5 sterol desaturase
YLR426W	__________	-1.23	303261	246909	unknown	unknown; similar to Fox2p, E. coli 3-oxoacyl-[acyl-carrier
YMR161W	HLJ1______	-1.08	130937	120855	unknown	unknown; similar to E. coli DnaJ
YNL217W	__________	+1.49	677165	1008466	unknown	unknown
YOL121C	RPS19A____	+1.07	12278023	13146086	protein synthesis	ribosomal protein S19A
YOR333C	__________	-1.18	206779	175147	unknown	unknown
YPR028W	YIP2______	+1.12	1855209	2076165	unknown	unknown; interacts with Ypt protein(s)
YBR008C	FLR1______	-1.10	158488	144661	fluconazole resistance	transporter, major facilitator superfamily
YCL029C	BIK1______	-1.26	253702	202057	mating; mitosis	microtubule-associated protein
YDL125C	HNT1______	+1.16	1179683	1372925	unknown	unknown; similar to protein kinase C inhibitor-I
YEL028W	__________	-1.07	128064	120203	unknown	unknown
YFR045W	__________	+1.10	184823	202947	unknown	unknown; similar to mitochondrial carrier family protein Ctp1p
YGR046W	__________	-1.04	285934	273920	unknown	unknown; similar to phage 1C ANTP-139 protein PIR:S46430
YHR063C	__________	+1.20	492232	588890	unknown	unknown; similar to Cbs2p
YIR033W	MGA2______	-1.13	617666	547294	transcription	chromatin remodeling (putative)
YJR093C	FIP1______	+1.04	326865	338461	mRNA polyadenylation	interacts with poly(A) polymerase
YKR089C	__________	-1.24	999368	804183	unknown	unknown
YLR244C	MAP1______	-1.06	715084	673922	protein processing	methionine aminopeptidase
YML113W	DAT1______	-1.20	1260314	1053307	transcription (putative)	oligo(dA)/oligo(dT)-binding protein
YNL029C	KTR5______	-1.11	223174	201459	protein glycosylation	putative mannosyltransferase
YNR068C	__________	-1.04	136574	131492	unknown	unknown
YOR145C	__________	-1.19	1343146	1125627	unknown	unknown
YPL123C	RNY1______	+1.00	182377	182607	unknown	ribonuclease, T2 family
YAL039C	CYC3______	+1.04	357751	370396	cytochrome c biosynthesis	cytochrome c heme lyase
YBR206W	__________	-1.05	552254	528254	unknown	unknown
YDR077W	SED1______	+2.95	2300581	6793809	unknown	putative cell surface glycoprotein
YDR444W	__________	-1.10	275539	250191	unknown	unknown
YGL137W	SEC27_____	-1.10	172818	156615	secretion	vesicle coat component
YGR244C	LSC2______	+1.63	626107	1022964	TCA cycle	succinyl-CoA ligase
YIL040W	__________	+1.20	404586	484230	unknown	unknown
YJL138C	TIF2______	-1.23	7609694	6192583	protein synthesis	translation initiation factor eIF4A
YKL134C	OCT1______	-1.21	194106	160749	mitochondrial protein targeting	mitochondrial intermediate peptidase
YLR068W	__________	-1.00	373615	372700	unknown	unknown
YLR438W	CAR2______	+1.62	308325	498777	arginine metabolism	ornithine aminotransferase
YNL229C	URE2______	-1.12	437926	391891	catabolite repression	inhibitor of Gln3p regulator
YOL133W	HRT1______	+1.08	339860	368575	unknown	unknown; similar to C. elegans protein of unknown function
YPR040W	__________	+1.04	378135	393585	unknown	unknown
YBR018C	GAL7______	-1.12	136092	121580	galactose metabolism	gal-1-phosphate uridyl transferase
YCL041C	__________	-1.17	146728	125887	unknown	unknown; similar to human papilloma virus (HPV) E6 protein
YDL135C	RDI1______	+1.14	732721	838093	signaling	rho GDP dissociation inhibitor for Rho1p
YDR260C	SWM1______	-1.32	214598	162258	sporulation	unknown
YEL040W	UTR2______	-1.01	2895293	2864063	unknown	unknown
YFR057W	__________	-1.26	281982	223164	unknown	unknown
YGR058W	__________	+1.01	219310	221189	unknown	unknown
YHR073W	__________	-1.28	480661	375905	unknown	unknown; similar to human oxysterol-binding protein (OSBP)
YJR104C	SOD1______	-1.04	8766346	8467700	oxidative stress response	copper-zinc superoxide dismutase
YKR101W	SIR1______	+1.06	316193	335209	silencing	reulator of silencing at HML and HMR
YLR256W	HAP1______	-1.29	10033094	7748888	transcription	heme-dependent transcription factor
YNL039W	TFC5______	-1.15	390067	338630	transcription	TFIIIB 90 kD subunit
YOR157C	PUP1______	-1.06	1680051	1588384	protein degradation	20S proteasome subunit (beta2)
YPL135W	ISU1______	+1.22	525232	642756	iron homeostasis	unknown; similar to iron-sulfur cluster protein nifU
YAL051W	OAF1______	-1.04	114040	109228	peroxisome proliferation	transcriptional activator of POX1
YBR218C	PYC2______	-1.17	629201	540014	TCA cycle	pyruvate carboxylase 2
YDR089W	__________	-1.18	173519	146797	unknown	unknown
YDR456W	NHX1______	-1.05	390845	373966	transport	Na+/H+ antiporter
YER147C	__________	-1.02	175447	171595	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YGL149W	__________	-1.10	142575	129760	unknown	unknown
YGR256W	GND2______	-1.40	1138264	810181	pentose phosphate cycle	6-phosphogluconate dehydrogenase
YIL052C	RPL34B____	+1.14	15760239	17959823	protein synthesis	ribosomal protein L34B
YJL150W	__________	+1.05	333158	350377	unknown	unknown
YKL146W	__________	-1.21	290336	239265	unknown	unknown; similar to members of a putative transporter family
YLR080W	__________	-1.04	158405	152891	unknown	unknown
YLR450W	HMG2______	-1.25	445659	355267	sterol metabolism	3-hydroxy-3-methylglutaryl-coenzyme A reductase
YMR183C	SSO2______	-1.14	965369	845214	secretion	post-Golgi t-SNARE
YNL241C	ZWF1______	+1.02	403303	410674	pentose phosphate cycle	glucose-6-phosphate dehydrogenase
YOL145C	CTR9______	-1.12	738428	662143	mitosis, chromosome segregation	unknown
YOR355W	GDS1______	-1.29	611057	471877	respiration (putative)	unknown; suppresses nam9-1
YPR052C	NHP6A_____	+1.04	697957	726168	chromatin structure	non-histone protein
YBR030W	__________	-1.20	243333	202039	unknown	unknown; similar to Sin3p
YCL053C	__________	-1.05	540641	512796
YDL147W	RPN5______	-1.03	1296095	1253185	protein degradation	26S proteasome subunit
YDR268W	MSW1______	+1.04	221173	229284	protein synthesis	tRNA synthetase, mitochondrial, Trp
YEL052W	AFG1______	-1.11	440445	395873	unknown	unknown; similar to members of the AAA family
YGR070W	ROM1______	+1.07	105834	113069	signaling	GDP/GTP exchange protein for Rho1p
YHR084W	STE12_____	-1.07	273858	256388	mating and pseudohyphal growth	transcription factor
YJR116W	__________	-1.10	308940	280968	unknown	unknown
YLR264W	RPS28B____	+1.09	8252396	9009669	protein synthesis	ribosomal protein S28B
YMR003W	__________	+1.08	269380	291733	unknown	unknown
YNL051W	__________	+1.01	141283	143105	unknown	unknown
YOR169C	__________	+1.03	2165163	2226756	unknown	unknown
YPL147W	PXA1______	+1.03	158277	162779	transport	long-chain fatty acid transporter, ABC family
YBR230C	__________	+1.42	244463	347072	unknown	unknown
YDR099W	BMH2______	-1.02	2652634	2608444	unknown	suppresses clathrin deficiency
YDR468C	TLG1______	+1.20	416621	501956	endocytosis	late Golgi t-SNARE
YER158C	__________	+1.29	172452	222164	unknown	unknown; similar to Afr1p
YGL161C	__________	-1.02	446657	436143	unknown	unknown
YGR268C	__________	+1.15	248402	286147	unknown	unknown
YIL064W	__________	-1.22	1022368	836333	unknown	unknown
YJL162C	__________	-1.30	1093139	841507	unknown	unknown; similar to E. coli DnaJ and other DnaJ-like
YKL158W	__________	-1.01	118324	116734
YLR092W	SUL2______	+1.04	134741	140104	transport	sulfate permease
YLR462W	__________	-1.24	232464	188101	unknown	unknown
YNL253W	__________	+1.01	285874	290031	unknown	unknown
YOL157C	__________	-1.14	206969	181801	unknown	putative alpha-glucosidase
YOR367W	SCP1______	+1.02	547979	561259	cytoskeleton (putative)	calponin homolog
YPR064W	__________	-1.08	126518	117147	unknown	unknown
YBR042C	__________	+1.02	324745	332173	unknown	unknown
YCL065W	__________	+1.16	603323	698547	unknown	unknown
YDL159W	STE7______	-1.00	253901	253764	signaling, pheromone and pseudohyphal growth pathways	MAPKK (mitogen-activated protein kinase kinase)
YDR280W	RRP45_____	-1.03	742276	723660	rRNA processing	3'->5' exoribonuclease
YEL063C	CAN1______	-1.22	320822	262575	transport	basic amino acid permease
YGR082W	TOM20_____	-1.19	919059	771889	mitochondrial protein targeting	mito. import receptor
YHR096C	HXT5______	-1.37	953542	695029	transport	hexose permease
YJR128W	__________	-1.00	132349	132282	unknown	unknown
YLR276C	DBP9______	-1.28	812925	636259	unknown	putative RNA helicase
YMR015C	ERG5______	-1.04	1006021	964124	sterol metabolism	C-22 sterol desaturase
YNL061W	NOP2______	-1.42	1083256	760478	nuclear organization	nucleolar protein
YOR181W	LAS17_____	-1.16	339238	293684	cytoskeleton	cortical actin patch component
YPL159C	__________	+1.15	269051	309664	unknown	unknown
YAR010C	__________	+1.01	110823	112017	unknown	unknown
YBR242W	__________	-1.02	642146	631078	unknown	unknown
YDR111C	__________	-1.04	182954	175630	unknown	unknown; similar to alanine aminotransferase (GB:Z48758)
YDR480W	DIG2______	-1.04	203417	194925	invasive growth	negative regulator
YER167W	BCK2______	-1.01	263797	260315	signaling	protein kniase C pathway
YGL173C	KEM1______	-1.03	1079417	1050221	mRNBA decay	DNA and RNA exonuclease
YGR280C	__________	-1.38	1347435	973143	unknown	unknown
YIL073C	SPO22_____	+1.01	257824	259556	sporulation	phospholipase A2, meiosis-specific
YJL174W	KRE9______	+1.01	944549	951830	cell wall biogenesis	beta-1,6-glucan assembly
YKL170W	MRPL38____	+1.08	425168	459652	protein synthesis	ribosomal protein, mitochondrial L38
YLR104W	__________	+1.20	223989	267773	unknown	unknown
YMR206W	__________	-1.06	138665	130842	unknown	unknown
YNL265C	IST1______	+1.04	335173	347996	salt tolerance (putative)	unknown; similar to Nuf1p
YOR003W	YSP3______	+1.01	235187	237194	protein degradation	subtilisin-like protease III
YOR379C	__________	-1.17	163530	140158	unknown	unknown
YPR076W	__________	-1.19	139603	117533	unknown	unknown
YBR054W	YRO2______	-1.09	708781	647621	unknown	putative heat shock protein
YCLX04W	__________	+1.06	156725	166627
YDL171C	GLT1______	-1.11	789147	708692	glutamate biosynthesis	glutamate synthase (NAPDPH) (GOGAT)
YDR292C	SRP101____	+1.05	115449	120774	secretion	signal recognition particle receptor subunit
YEL075C	__________	-1.10	170374	155588	unknown	unknown; similar to other subtelomerically-encoded proteins
YGR094W	VAS1______	-1.24	298216	239990	protein synthesis	tRNA synthetase, valyl
YHR108W	GGA2______	-1.30	1147542	885855	secretion (putative)	unknown; binds ARF
YJR140C	HIR3______	-1.19	538557	451471	transcription	regulator of histone transcription
YMR027W	HRT2______	-1.03	406849	394533	transposition, Ty3 (putative)	unknown
YNL073W	MSK1______	-1.10	235559	214378	protein synthesis	tRNA synthetase, mitochondrial, lysyl
YPL171C	OYE3______	+1.03	109776	113335	unknown	NAPDH dehydrogenase (old yellow enzyme)
YAR033W	__________	+1.03	204817	209991	unknown	unknown; similar to subtelomerically-encoded proteins
YBR254C	TRS20_____	+1.15	330828	379358	secretion (putative)	transport protein particle (TRAPP) subunit, 20 kD
YDR123C	INO2______	-1.04	173007	165600	phospholipid biosynthesis	transcription factor
YDR492W	__________	-1.21	500513	414280	unknown	unknown
YER178W	PDA1______	-1.04	2130305	2048098	glycolysis	pyruvate dehydrogenase
YGL185C	__________	-1.14	243967	213744	unknown	unknown; similar to D-2-hydroxyacid dehydrogenase
YGR292W	MAL12_____	-1.03	124618	120997	maltose utilization	alpha-glucosidase
YIL084C	SDS3______	-1.04	151906	145404	silencing	(putative) transcriptional regulator
YJL186W	MNN5______	-1.28	782968	610535	protein glycosylation	alpha-1,2-mannosyltransferase (putative)
YKL182W	FAS1______	-1.00	106590	106435	fatty acid metabolism	fatty-acyl-CoA synthase, beta subunit
YLR116W	MSL5______	-1.19	210663	177643	mRNA splicing	branchpoint bridging protein (commitment complex component)
YMR218C	TRS130____	-1.11	153224	137425	secretion	membrane targeting complex (TRAPP) subunit
YNL277W	MET2______	-1.00	206659	205769	methionine biosynthesis	homoserine O-acetyltransferase
YOR015W	__________	+1.21	540989	655364	unknown	unknown
YOR391C	__________	-1.03	125041	121059	unknown	unknown
YPR088C	SRP54_____	-1.35	1214193	900366	secretion	signal recognition particle subunit
YBR066C	NRG2______	+1.10	122072	134530	unknown	unknown
YCR004C	YCP4______	+1.42	1058669	1499339	unknown	unknown; similar to S. pombe brefeldin A resistance protein
YDL183C	__________	+1.13	166001	188051	unknown	unknown
YDR304C	CYP5______	+1.06	758733	806474	protein folding	peptidyl-prolyl cis-trans isomerase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YGR106C	__________	+1.04	1979101	2052137	unknown	unknown; similar to Vibrio anguillarum chemotaxis methyl
YHR120W	MSH1______	-1.12	354992	315564	DNA repair	MutS homolog; mitochondrial DNA repair
YJR152W	DAL5______	-1.06	214967	201969	allantoin utilization	allantoate permease
YLR299W	ECM38_____	+1.14	156065	178566	glutathione biosynthesis	gamma-glutamyltransferase
YMR038C	LYS7______	-1.17	617725	525964	oxidative stress response	copper chaperone for superoxide dismutase Sod1p
YNL085W	MKT1______	-1.64	735634	447748	viral propagation	retroviral protease signature protein
YOR203W	__________	-1.21	611129	506758	unknown	unknown
YPL183C	__________	-1.26	775524	615184	unknown	unknown
YBL005W	TY1A______	-1.20	2695370	2254766	unknown	unknown
YBR266C	__________	-1.81	285247	157386	unknown	unknown
YDL005C	MED2______	-1.17	354750	301939	transcription	RNA polymerase II mediator subunit
YDR135C	YCF1______	-1.17	390079	334602	transport	vacuolar glutathione S-conjugate transporter
YDR504C	__________	+1.16	326227	379115	unknown	unknown
YFL003C	MSH4______	-1.13	147054	129863	meiosis, recombination	MutS homolog
YGL197W	MDS3______	+1.02	106445	108387	meiosis	gene expression regulator (putative)
YHL004W	MRP4______	-1.03	375144	363359	protein synthesis	ribosomal protein, mitochondrial small sunubit
YIL096C	__________	-1.11	450522	404742	unknown	unknown
YJL198W	__________	-1.14	206787	181438	unknown	unknown; similar to Pho87p, member of the phosphate
YKL194C	MST1______	+1.00	106703	107091	protein synthesis	tRNA synthetase, mitochondrial, threonyl
YLR128W	__________	-1.02	143946	140657	unknown	unknown
YML005W	__________	+1.02	186450	189574	unknown	unknown
YNL287W	SEC21_____	-1.06	971167	912402	secretion	vesicle coat component
YOR027W	STI1______	-1.36	946269	696276	protein folding	component of Hsp70-Hsp90 complexes
YPL005W	__________	-1.05	138634	131849	unknown	unknown
YPR100W	__________	+1.09	925072	1010480	unknown	unknown
YBR078W	ECM33_____	-1.48	1470078	990027	cell wall biogenesis	unknown
YCR016W	__________	-1.36	439582	323994	unknown	unknown
YDL195W	SEC31_____	-1.28	210267	164046	secretion	vesicle coat component
YDR316W	__________	-1.38	261256	189768	unknown	unknown
YER018C	SPC25_____	-1.05	202822	194040	cytoskeleton	spindle pole body component
YGL005C	__________	+1.01	245350	248998	unknown	unknown; similar to Xenopus kinesin-related protein Eg5
YGR116W	SPT6______	-1.05	267706	254862	transcription	elongation factor
YJL005W	CYR1______	-1.01	14650564	14449817	cell cycle	adenylate cyclase
YKL005C	__________	+1.02	270732	276036	unknown	unknown; similar to Drosophila transcription factor TFIIS,
YLL005C	__________	+1.02	200400	205231	unknown	unknown
YLR311C	__________	-1.08	145020	133906	unknown	unknown
YMR049C	__________	-1.53	362165	236975	unknown	unknown
YNL097C	PHO23_____	+1.01	285510	287471	phosphate signaling	transcriptional regulator of PHO5
YOL005C	RPB11_____	+1.12	725815	813193	transcription	RNA polymerase II subunit
YOR215C	__________	+1.15	321778	368515	unknown	unknown
YPL194W	DDC1______	+1.02	127287	130100	cell cycle, checkpoint	unknown
YAR061W	__________	-1.08	120302	110986	unknown	unknown; similar to N-terminus of Flo1p
YBL015W	ACH1______	-1.04	143585	138153	acetyl-CoA metabolism	acetyl-CoA hydrolase
YBR278W	DPB3______	+1.03	168441	173568	DNA replication	polymerase epsilon C subunit
YDL017W	CDC7______	-1.04	155353	148797	cell cycle	S phase protein kinase
YDR147W	EKI1______	+1.08	245481	264685	phospholipid metabolism	ethanolamine kinase
YDR516C	__________	+1.14	170047	193389	unknown	unknown; similar to Glk1p
YFL013C	__________	-1.16	212079	182655	unknown	unknown; similar to Ifh1p and Nab3p
YGL209W	MIG2______	+1.01	107115	108366	glucose repression	transcriptional repressor
YHL013C	__________	+1.07	392977	422220	unknown	unknown
YIL107C	PFK26_____	+1.23	156042	192111	fructose and mannose metabolism	6-Phosphofructose-2-kinase
YJL210W	PEX2______	+1.10	264238	291730	peroxisome biogenesis	integral membrane protein
YKL206C	__________	+1.21	310729	375453	unknown	unknown
YLR140W	__________	+1.10	119806	132345	unknown	unknown
YML014W	__________	-1.39	580298	418658	unknown	unknown; similar to Diptheria toxin resistance protein
YMR242C	RPL20A____	-1.10	13346689	12147234	protein synthesis	ribosomal protein L20A
YNL299W	TRF5______	-1.19	201419	169857	mitosis	related to DNA topoisomerase I
YOR039W	CKB2______	-1.23	697349	569012	salt tolerance	casein kinase II regulatory subunit
YPL017C	__________	+1.19	218247	260115	unknown	unknown; similar to Lpd1p
YPR112C	MRD1______	-1.12	140192	125082	unknown	unknown; similar to Pab1p, Pub1p, Nsr1p, Nop4p and other
YBR089W	__________	-1.22	393550	322746	unknown	unknown
YCR026C	__________	-1.18	165343	140133	unknown	unknown; similar to human plasma membrane glycoprotein PCI
YDL207W	GLE1______	-1.23	300398	244823	mRNA export	unknown
YDR326C	__________	-1.08	136189	125717	unknown	unknown
YER029C	SMB1______	-1.19	359591	301383	mRNA splicing	U1 snRNP protein
YGL017W	ATE1______	-1.12	196903	176182	protein synthesis	tRNA transferase, arginyl
YGR128C	__________	-1.27	336199	265468	unknown	unknown; similar to Haemophilus glutamate-ammonia-ligase
YHR142W	CHS7______	+1.40	475680	666926	cell wall biogenesis	ER membrane protein; chitin synthase export
YJL017W	__________	+1.05	151318	158215	unknown	unknown
YKL016C	ATP7______	+1.52	1090028	1655777	ATP synthesis	F1F0-ATPase complex, FO D subunit
YLL017W	__________	+1.04	145869	151948	unknown	unknown
YLR322W	__________	-1.10	121084	110406	unknown	unknown
YMR059W	SEN15_____	-1.13	225650	198836	tRNA splicing	splicing endonuclease subunit
YNL109W	__________	+1.01	445796	450995	unknown	unknown
YOL017W	__________	-1.02	156623	152833	unknown	unknown
YOR227W	__________	+1.01	478472	484988	unknown	unknown
YPL206C	__________	+1.28	466247	596905	unknown	unknown; similar to Mycoplasma genitalium glycerophosphoryl
YBL027W	RPL19B____	+1.19	15760938	18778077	protein synthesis	ribosomal protein L19B
YBR290W	BSD2______	+1.01	312137	316447	transport	Cu(2+) transporter
YDL029W	ARP2______	-1.02	619252	606680	cytoskeleton	actin-related protein
YDR159W	SAC3______	-1.21	393452	324099	leucine transport	nuclear protein
YDR528W	HLR1______	-1.26	314085	249569	trehalose metabolism (putative)	unknown; pKA antagonist
YFL022C	FRS2______	-1.64	1139239	695737	protein synthesis	tRNA synthetase, phenylalanyl
YGL221C	NIF3______	-1.14	612871	535296	unknown	unknown
YHL025W	SNF6______	-1.01	430961	425471	transcription	component of SWI/SNF global activator complex
YIL119C	RPI1______	+1.02	183855	187061	signaling, Ras pathway	negative regulator of ras-cAMP pathway
YJL222W	VTH2______	+1.06	105845	112584	vacuolar protein targeting	unknown; similar to Vps10p
YKL218C	SRY1______	+1.25	169637	211933	serine metabolism	serine racemase
YLR152C	__________	+1.11	122049	135758	unknown	unknown; similar to Ecm3p
YNL311C	__________	+1.01	192565	194622	unknown	unknown
YOR051C	__________	-1.19	1138738	957014	unknown	unknown
YPL029W	SUV3______	-1.16	229371	197413	RNA processing, mitochondrial	RNA helicase
YPR124W	CTR1______	-1.26	1086282	860352	transport	copper transporter
YBR100W	__________	+1.05	159101	167513	unknown	unknown
YCR037C	PHO87_____	-1.13	139460	123149	transport	inorganic phosphate permease
YDL219W	__________	+1.21	406324	493534	unknown	unknown
YDR338C	__________	-1.04	134945	130345	unknown	unknown
YER040W	GLN3______	-1.16	237367	204925	nitrogen catabolite repression	transcription factor
YGL029W	CGR1______	+1.21	781006	947716	unknown	unknown; similar to human chromatin assembly factor I p150
YGR140W	CBF2______	+1.16	97885	113790	mitosis	kinetochore protein complex CBF3, 110 KD subunit

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YHR153C	SPO16_____	+1.17	128523	150181	meiosis, spore formation	unknown
YJL029C	VPS53_____	+1.08	238464	257116	vacuolar protein targeting (putative)	unknown
YKL028W	TFA1______	-1.07	407400	382526	transcription	TFIIE 66 kD subunit
YLL029W	__________	+1.17	302125	353775	unknown	unknown
YLR334C	__________	-1.16	2866385	2471955	unknown	unknown
YMR071C	__________	+1.11	689764	766858	unknown	unknown
YNL121C	TOM70_____	-1.34	472070	351288	mitochondrial protein targeting	outer membrane translocase component
YOL029C	__________	+1.06	464847	494748	unknown	unknown
YOR239W	ABP140____	-1.14	436758	384640	cytoskeleton	F-actin binding protein
YPL218W	SAR1______	+1.14	2646231	3020716	secretion	GTP-binding protein of the ARF family
YER189W	__________	-1.04	163905	157171	unknown	unknown; similar to subtelomerically-encoded proteins
YBL039C	URA7______	-1.49	600805	403184	pyrimidine biosynthesis	CTP synthase 1
YBR302C	COS2______	+1.59	613160	973791	unknown	unknown; similar to subtelomerically-encoded proteins
YDL041W	__________	-1.15	113938	98867	unknown	unknown
YDR540C	__________	+1.00	134372	134466	unknown	unknown
YGL232W	__________	+1.07	454445	488365	unknown	unknown; similar to dihydropteroate synthase
YHL036W	MUP3______	+1.25	167998	209665	transport	methionine permease
YIL131C	FKH1______	+1.10	93436	102681	unknown	unknown; similar to Drosophila fork head protein
YJR010W	MET3______	+1.20	240935	288148	methionine biosynthesis	sulfate adenylyltransferase
YKR005C	__________	+1.14	117524	133601	unknown	unknown
YLR162W	__________	+1.22	585574	713778	unknown	unknown
YMR266W	__________	-1.16	118114	101459	unknown	unknown
YNL323W	BRE3______	-1.15	252792	219925	secretion (putative)	unknown; brefeldin A sensitive
YOR063W	RPL3______	-1.09	13420053	12333892	protein synthesis	ribosomal protein L3
YPL041C	__________	-1.24	268294	215973	unknown	unknown
YPR136C	__________	-1.59	207000	130058	unknown	unknown
YBR111C	YSA1______	+1.26	718970	908314	unknown	unknown; similar to Drosophila serendipity protein
YCR049C	__________	+1.02	123169	125203	unknown	unknown
YDL231C	BRE4______	-1.03	188503	183651	secretion (putative)	unknown; major facilitator superfamily; brefeldin A sensitive
YDR350C	TCM10_____	+1.04	200775	207845	unknown	unknown
YER050C	__________	+1.29	362204	466404	unknown	unknown
YGL041C	__________	+1.07	274447	292753	unknown	unknown
YGR152C	RSR1______	+1.06	382739	404733	bud site selection	GTP-binding protein, ras superfamily
YHR165C	PRP8______	+1.08	105445	113363	mRNA splicing	U4/U6, U5 snRNP protein
YJL042W	MHP1______	+1.06	119103	126178	cytoskeleton	microtubule-associated protein
YKL039W	PTM1______	-1.18	536736	453120	unknown	unknown; similar to Yhl017p, member of the major facilitator superfamily
YLL041C	SDH2______	-1.08	303011	281742	TCA cycle, oxidative phosphorylation	succinate dehydrogenase
YLR346C	__________	+1.28	117596	150368	unknown	unknown
YMR082C	__________	-1.08	102010	94721	unknown	unknown
YNL133C	__________	+1.15	172116	198346	unknown	unknown
YOL041C	NOP12_____	+1.01	124833	126075	unknown	unknown; nucleolar protein
YOR251C	__________	-1.15	561461	488689	unknown	unknown; similar to thiosulfate sulfurtransferases
YPL230W	USV1______	-1.16	328211	281975	unknown	unknown; expression increases upon starvation
YBL051C	__________	-1.26	446202	355155	unknown	unknown; similar to RNA-binding proteins, contains 1 RRM domain
YDL053C	__________	+1.06	470699	498155	unknown	unknown
YDR180W	SCC2______	-1.08	278409	258765	mitosis, sister chromatid cohesion	unknown; binds chromosomes
YFL044C	__________	-1.08	137351	127734	unknown	unknown
YGL244W	RTF1______	-1.03	384826	373412	transcription	regulator of Spt15 DNA binding properties
YHL047C	TAF1______	+1.16	184983	214155	transport	triacetylfusarinine C transporter
YIL143C	SSL2______	+1.00	215189	215276	transcription; DNA repair	TFIIH helicase
YJR021C	REC107____	+1.14	197734	226015	meiosis, recombination	ds break formation complex subunit
YKR017C	__________	+1.15	149291	172008	unknown	unknown
YLR174W	IDP2______	+1.19	117464	139239	TCA cycle	isocitrate dehydrogenase
YML046W	PRP39_____	-1.11	161232	145299	mRNA splicing	U1 snRNP protein
YMR278W	__________	-1.06	199378	188053	unknown	unknown; similar to phosphomannomutase
YNL335W	__________	+1.04	127069	131950	unknown	unknown; similar to Myrothecium verrucaria cyanamide hydratase
YOR075W	UFE1______	+1.14	289336	329752	secretion	ER membrane t-SNARE
YPL053C	KTR6______	+1.14	348072	398307	protein glycosylation	mannosylphosphate transferase
YPR146C	__________	+1.28	247310	315856	unknown	unknown
YBR123C	TFC1______	-1.08	282440	262489	transcription	TFIIIC 95 kD subunit
YCR061W	__________	-1.11	185808	166841	unknown	unknown
YDL243C	AAD4______	-1.03	241830	234681	unknown	hypothetical aryl-alcohol dehydrogenase
YDR362C	TFC6______	-1.03	224488	217483	transcription	TFIIIC 91 kD subunit
YGL053W	__________	+1.04	323949	335963	unknown	unknown
YHR177W	__________	+1.33	141957	188468	unknown	unknown
YJL054W	TIM54_____	+1.05	117990	123597	mitochondrial protein targeting	inner membrane translocase component
YKL051W	__________	+1.37	265536	363605	unknown	unknown
YLL053C	__________	+1.09	307828	335557	unknown	unknown; similar to putative aquaporin Ypr192p, member of
YLR358C	__________	+1.05	289188	304907	unknown	unknown
YMR093W	__________	-1.26	649933	514648	unknown	unknown
YNL145W	MFA2______	+1.07	113605	121552	mating	a-factor precursor
YOR263C	__________	-1.14	182106	159663	unknown	unknown; similar to adenosine A1 receptors
YPL242C	IQG1______	-1.01	119159	117456	cytoskeleton	IQGAP homolog
YBL063W	KIP1______	+1.05	109786	115096	mitosis, spindle assembly	kinesin related protein
YDL065C	PEX19_____	+1.11	371847	411034	peroxisome biogenesis	unknown
YDR192C	NUP42_____	-1.04	170722	164400	nuclear protein targeting	nuclear pore protein
YFL056C	AAD6______	-1.21	198656	163936	unknown	hypothetical aryl-alcohol dehydrogenase
YGL256W	ADH4______	-1.18	364000	307460	glycolysis	alcohol dehydrogenase IV
YHR007C	ERG11_____	-1.60	2034021	1270298	sterol metabolism	cytochrome P450 lanosterol 14a-demethylase
YIL155C	GUT2______	-1.07	172545	160558	glycerol metabolism	glycerol-3-phosphate dehydrogenase, mitochondrial
YJR032W	CPR7______	-1.04	443684	428359	protein folding	peptidyl-prolyl cis/trans isomerase
YKR029C	__________	+1.02	197517	202448	unknown	unknown; similar to E(z) Enhancer of zeste in the C-terminal
YLR186W	__________	-1.30	941576	723535	unknown	unknown
YMR290C	HAS1______	-1.58	1269644	803048	unknown	RNA helicase
YNR008W	LRO1______	-1.14	160015	139994	sterol metabolism (putative)	lecithin cholesterol acyl transferase (putative)
YOR087W	__________	-1.42	165098	116457	unknown	unknown
YPL063W	__________	-1.18	1166841	985527	unknown	phosphatase
YPR158W	__________	-1.04	287542	276622	unknown	unknown
YBR135W	CKS1______	+1.06	1085060	1154757	cell cycle	portein kinase regulator
YCR072C	__________	-1.55	318650	206210	unknown	unknown; similar to nuclear mRNA processing protein Prp4p
YDR007W	TRP1______	+1.14	539056	616292	tryptophan biosynthesis	phosphoribosylanthranilate isomerase
YDR372C	__________	-1.00	421891	421406	unknown	unknown
YER069W	ARG5,6____	+1.07	212406	227484	arginine biosynthesis	acetylglutamate kinase and acetylglutamyl-phosphate reductase
YGL065C	ALG2______	+1.00	290525	291259	protein glycosylation	glycosyltransferase
YGR172C	YIP1______	-1.07	661448	617876	unknown	unknown; interacts with Ypt protein(s)
YHR189W	__________	+1.33	111301	147937	protein synthesis	tRNA hydrolase, peptidyl, putative
YJL066C	__________	+1.00	224983	225772	unknown	unknown
YKL063C	__________	+1.11	456708	507527	unknown	unknown
YLL065W	GIN11_____	+1.08	160810	173991	unknown	growth inhibitor
YLR370C	ARC18_____	+1.09	777217	848040	cytoskeleton	cortical actin patch integrity; Arp2/3 complex subunit

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YMR105C	PGM2______	+1.09	170569	185109	glycolysis	phosphoglucomutase
YNL157W	__________	+1.50	650411	973541	unknown	unknown
YOL063C	__________	-1.00	128323	127754	unknown	unknown
YOR275C	__________	-1.03	209208	202338	unknown	unknown
YPL253C	VIK1______	-1.08	200254	185736	nuclear fusion (putative)	Kar3p interactor
YMR320W	__________	-1.06	152076	143356	unknown	unknown
YBL075C	SSA3______	-1.45	263601	181626	ER and mitochondrial translocation	cytosolic HSP70
YDL077C	VAM6______	-1.08	232990	215130	protein degradation	vacuolar carboxypeptidase Y
YDR204W	COQ4______	+1.08	262792	285086	ubiquinone biosynthesis	unknown
YFL068W	__________	-1.45	969244	669906	unknown	unknown; similar to other subtelomerically-encoded proteins
YGR005C	TFG2______	-1.15	465092	405876	transcription	TFIIF 54 kD subunit
YHR019C	DED81_____	-1.35	4346234	3231351	protein synthesis	tRNA synthetase, arparaginyl
YIL166C	__________	-1.11	228763	207002	unknown	unknown; major facilitator superfamily
YJR044C	__________	+1.10	500693	552119	unknown	unknown; similar to Drosophila yakuba NADH dehydrogenase
YKR041W	__________	+1.02	159651	162793	unknown	unknown
YLR198C	__________	+1.06	3848740	4068685	unknown	unknown
YML068W	__________	-1.10	235575	214590	unknown	unknown
YMR300C	ADE4______	+1.01	964955	975629	purine biosynthesis	amidophosphoribosyltransferase
YNR020C	__________	+1.17	273801	321354	unknown	unknown
YOR099W	KTR1______	+1.07	1149570	1227774	protein glycosylation	mannosyltransferase
YPL075W	GCR1______	-1.17	201930	172875	glycolysis	transcriptional activator
YPR166C	MRP2______	+1.21	348074	422463	protein synthesis	ribosomal protein, mitochondrial S14
YBR147W	__________	-1.01	110522	108954	unknown	unknown
YCR085W	__________	-1.07	123143	115498	unknown	unknown
YDR019C	GCV1______	+1.12	185983	208455	amino acid metabolism	glycine decarboxylase T subunit
YDR384C	__________	-1.57	513735	326197	unknown	unknown; similar to Y. lipolytica Gpr1p
YER081W	SER3______	+1.00	560908	561029	serine biosynthesis	3-phosphoglycerate dehydrogenase
YGL077C	HNM1______	+1.04	616192	641655	transport	choline permease
YGR184C	UBR1______	+1.02	109384	112090	protein degradation, ubiquitin-mediated	ubiquitin-protein ligase
YHR201C	PPX1______	-1.09	1050913	967394	unknown	vacuolar exopolyphosphatase
YJL078C	PRY3______	+1.08	110805	119434	unknown	unknown; similar to plant PR-pathogen related proteins
YKL075C	__________	-1.06	240052	226416	unknown	unknown
YLR010C	__________	-1.00	157464	157081	unknown	unknown
YLR382C	NAM2______	-1.09	173313	158485	protein synthesis	tRNA synthetase, mitochondrial, leucyl
YNL169C	PSD1______	-1.08	251485	232432	phospholipid metabolism	phosphatidylserine decarboxylase
YOL075C	__________	-1.06	246363	232600	unknown	putative ATP-dependent transporter
YOR287C	__________	-1.14	577368	507078	unknown	unknown; similar to PITSLRE protein kinase isoforms
YPL263C	KEL3______	-1.31	308561	236066	unknown	unknown; similar to Kel1p and Kel2p
YBL087C	RPL23A____	-1.06	13024230	12302215	protein synthesis	ribosomal protein L23A
YDL089W	__________	-1.09	205108	188100	unknown	unknown
YDR212W	TCP1______	-1.26	1295573	1031799	protein folding	cytoplasmic chaperonin complex
YFR012W	__________	-1.30	226765	173813	unknown	unknown
YGR017W	__________	-1.00	125173	124675	unknown	unknown; similar to Nmd2p
YHR030C	SLT2______	+1.84	1575325	2902179	signaling, PKC1 pathway	MAP kinase (mitogen-activated protein kinase)
YIL177C	__________	-1.02	795764	779836	unknown	unknown; similar to subtelomerically-encoded proteins
YJR056C	__________	-1.00	341186	339690	unknown	unknown
YKR053C	YSR3______	+1.05	281088	296209	sphingolipid metabolism	dihydrosphingosine-1-phosphate phosphatase
YLR210W	CLB4______	-1.12	207922	186312	cell cycle	G2/M cyclin
YML080W	__________	-1.17	514519	439704	unknown	unknown; similar to Azospirillum brasilense nifR3
YMR310C	__________	-1.43	705453	492538	unknown	unknown
YNR032W	PPG1______	+1.07	296063	318016	glycogen metabolism	protein phosphatase
YOR111W	__________	-1.01	236114	233486	unknown	unknown
YPL087W	YDC1______	+1.23	506083	624060	sphingolipid metabolism	dihyroceramidase
YPR178W	PRP4______	-1.11	337524	304989	mRNA splicing	U4/U6 snRNP protein
YBR159W	__________	-1.06	958348	907720	unknown	unknown; similar to human estradiol
YCR096C	HMRA2_____	+1.22	725407	886136	unknown	mating type a specific
YDR031W	__________	+1.28	203761	261831	unknown	unknown
YDR396W	__________	+1.32	646424	851577	unknown	unknown
YER092W	__________	+1.10	403131	444697	unknown	unknown
YGL089C	MF(ALPHA)2	-1.13	4160616	3684103	mating	alpha factor
YGR196C	__________	-1.02	307532	301094	unknown	unknown
YHR213W	__________	-1.24	185235	149206	unknown	unknown; similar to the N-terminus of Flo1p
YJL090C	DPB11_____	-1.07	242183	225800	DNA replication	DNA polymerase II complex
YKL087C	CYT2______	+1.05	335511	350897	cytochrome c1 biosynthesis	cytochrome c1 heme lyase
YLR022C	__________	-1.02	784040	770568	unknown	unknown
YLR394W	CST9______	-1.10	210106	191124	meiosis, synapsis	unknown
YMR128W	ECM16_____	-1.45	732663	505819	cell wall biogenesis	unknown
YNL181W	__________	-1.18	416504	352161	unknown	unknown
YOL087C	__________	-1.07	268033	250119	unknown	unknown
YPL275W	__________	-1.07	129864	121866	unknown	unknown; similar to formate dehydrogenases
YAL007C	ERP2______	+1.23	539803	662638	membrane trafficking; secretion (putative)	unknown
YBR171W	SEC66_____	+1.10	370616	406955	secretion	ER protein translocation subcomplex subunit
YCRX01W	__________	-1.05	98285	94049
YDR042C	__________	-1.20	113594	94377	unknown	unknown
YDR409W	__________	-1.30	893058	685626	unknown	unknown; similar to Nfi1p
YER104W	RTT105____	-1.27	177988	140062	transposition (putative)	unknown
YGL102C	__________	+1.20	15690378	18897369	unknown	unknown
YGR209C	TRX2______	+1.04	2917944	3044972	DNA replication	thioredoxin II
YIL006W	__________	-1.15	273018	237512	unknown	unknown; similar to Flx1p, Yel006p, and other members of
YJL103C	__________	+1.03	174560	180270	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YKL099C	__________	-1.25	845241	674311	unknown	unknown; similar to human kinesin heavy chain
YLR035C	MLH2______	-1.04	179677	172888	DNA repair	MutL homolog; mismatch repair; non-Mendelian segregation
YLR407W	__________	+1.23	214903	264163	unknown	unknown
YMR140W	__________	-1.16	145151	124703	unknown	unknown
YNL194C	__________	-1.10	129883	117789	unknown	unknown; similar to Sur7p
YOL100W	PKH2______	+1.08	279715	301667	unknown	protein kinase (ser/thr)
YOR310C	NOP58_____	-1.20	3046801	2532917	ribosome biogenesis	nucleolar protein
YPR005C	HAL1______	+1.07	166976	177907	salt tolerance	unknown
YBL100C	__________	-1.59	193088	121094	unknown	unknown
YCL005W	__________	-1.16	305478	263813	unknown	unknown
YDL102W	CDC2______	-1.14	179136	157824	DNA replication	DNA polymerase delta catalytic 125 KD subunit
YDR225W	HTA1______	+1.05	6696164	7058462	chromatin structure	histone H2A
YEL006W	__________	-1.21	276340	227490	unknown	unknown; similar to Aac1p, Pet9p, Aac3p, Yil006p and other
YFR025C	HIS2______	-1.04	197901	190902	histidine biosynthesis	histidinol phosphatase
YGR028W	MSP1______	+1.27	196583	249338	mitochondrial protein targeting	AAA-ATPase
YHR042W	NCP1______	+1.00	203075	204039	microsomal electron transfer	NADP-cytochrome P450 reductase
YIR013C	GAT4______	+1.07	116058	124067	transcription (putative)	DNA binding protein, GATA family
YJR069C	HAM1______	+1.09	661149	717746	6-N-hydroxylaminopurine resistance	unknown
YKR066C	CCP1______	+1.23	675000	833322	oxidative stress response	cytochrome-c peroxidase
YLR223C	IFH1______	+1.10	467208	516129	rRNA processing	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YML093W	__________	-1.30	377825	289653	unknown	unknown
YNL006W	LST8______	-1.15	363767	315481	secretion	unknown; post-Golgi
YNR045W	PET494____	-1.10	251529	228157	protein synthesis	translation activator of COX3
YOR124C	UBP2______	+1.03	627180	644964	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YPL100W	__________	-1.03	228359	220881	unknown	unknown; similar to Yfr021p
YPR191W	QCR2______	+1.21	716595	867356	oxidative phosphorylation	ubiquinol--cytochrome-c reductase 40 kD subunit
YAL019W	FUN30_____	-1.17	235846	202289	unknown	unknown; similar to SNF2 transcriptional regulator
YBR183W	YPC1______	+1.33	183344	243563	sphingolipid metabolism	alkaline ceramidase
YCRX13W	__________	-1.14	302966	265645
YDR054C	CDC34_____	-1.29	298954	232553	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YDR421W	__________	-1.09	196781	181315	unknown	unknown
YER116C	__________	-1.17	168605	144273	unknown	unknown
YGL114W	__________	-1.03	239587	233632	unknown	unknown; major facilitator superfamily
YGR221C	__________	+1.11	149016	165292	unknown	unknown
YIL017C	VID28_____	+1.10	140040	154596	vacuolar protein targeting (putative)	unknown
YJL115W	ASF1______	+1.27	465524	593228	transcription	anti-silencing protein
YKL111C	__________	+1.20	278756	335229	unknown	unknown
YLR045C	STU2______	+1.03	155690	160833	cytoskeleton	spindle pole body component
YLR417W	VPS36_____	+1.03	237913	245618	vacuolar protein targeting	unknown?
YMR152W	YIM1______	-1.11	372644	334952	protein processing	mitochondrial inner membrane protease
YNL206C	RTT106____	-1.05	289378	275309	transposition	unknown; similar to SSRP proteins (DNA structure-specific
YOL110W	SHR5______	+1.02	227056	230925	protein processing	localization and palmitoylation of Ras proteins
YOR322C	__________	-1.21	228998	189481	unknown	unknown
YPR017C	DSS4______	-1.01	314240	310633	secretion	GDP/GTP exchange factor for Sec4p
YBL110C	__________	-1.25	187737	150059
YCL018W	LEU2______	-1.36	267093	196696	leucine biosynthesis	beta-isopropyl-malate dehydrogenase
YDL114W	__________	+1.06	105813	112560	unknown	unknown
YEL017W	__________	-1.15	305413	265097	unknown	unknown
YFR035C	__________	-1.06	434744	410266	unknown	unknown
YHR053C	CUP1-1____	+1.02	3562856	3645922	Cu2+ ion homeostasis	metallothionein
YIR023W	DAL81_____	+1.11	118012	130931	transcription	activator of allantoin and urea catabolic genes
YJR082C	__________	+1.18	224590	264294	unknown	unknown
YKR078W	__________	+1.03	169848	175585	unknown	unknown; similar to Uso1p
YLR233C	EST1______	+1.11	114445	126613	telomere length regulation	putative end-binding protein
YML102W	CAC2______	-1.15	331005	288403	chromatin structure	chromatin assembly factor I subunit
YNL018C	__________	-1.19	153787	129767	unknown	unknown; similar to Drosophila melanogaster
YNR057C	BIO4______	-1.06	229966	217631	biotin biosynthesis	dethiobiotin synthetase
YOR136W	IDH2______	+1.46	558936	813340	TCA cycle	isocitrate dehydrogenase
YPL112C	__________	-1.17	485094	414372	unknown	unknown
YPR203W	__________	-1.03	190636	185229	unknown	unknown; similar to other subtelomerically-encoded proteins
YAL030W	SNC1______	+1.35	356946	482908	secretion	Golgi v-SNARE
YBR195C	MSI1______	-1.20	224681	186661	chromatin structure	chromatin assembly factor I subunit
YDR066C	__________	+1.10	172932	190957	unknown	unknown; similar to Yer139p
YDR433W	__________	-1.05	108399	103102	unknown	unknown
YER127W	LCP5______	-1.33	652081	491847	rRNA processing, putative	unknown
YGL126W	SCS3______	+1.18	97106	114363	phospholipid metabolism	inositol phospholipid biosynthesis
YGR233C	PHO81_____	+1.19	172775	205725	cell cycle	Pho85p kinase inhibitor
YIL029C	__________	+1.22	130633	159870	unknown	unknown
YJL127C	SPT10_____	-1.14	145327	127296	transcription	transcriptional regulator
YKL123W	__________	+1.28	121532	154964	unknown	unknown
YLR057W	__________	+1.08	181073	195409	unknown	unknown
YLR427W	__________	-1.06	200661	189385	unknown	unknown
YMR162C	__________	-1.11	115088	103667	unknown	unknown; similar to members of the Drs2p family of P-type
YNL218W	__________	-1.03	121885	118366	unknown	unknown; similar to E. coli DNA polymerase III gamma and tau
YOL122C	SMF1______	+1.03	284290	293160	transport	high affinity manganese transporter
YOR334W	MRS2______	-1.03	165407	161148	mRNA splicing, mitochondrial	unknown
YPR029C	APL4______	-1.12	923281	823504	secretion	AP complex subunit
YBR009C	HHF1______	+1.09	7594745	8290480	chromatin structure	histone H4
YCL030C	HIS4______	-1.34	847346	632274	histidine biosynthesis	histidinol dehydrogenase
YDL126C	CDC48_____	-1.07	806264	750969	ubiquitin mediated degredation	microsomal AAA ATPase family
YDR249C	__________	-1.04	139861	134966	unknown	unknown; similar to cytochromes
YEL029C	__________	+1.12	214013	238963	unknown	unknown; similar to putative Salmonella phosphotransferase
YFR046C	__________	+1.01	252736	256439	unknown	unknown
YGR047C	TFC4______	+1.12	144292	160918	transcription	TFIIIC 131 kD subunit
YIR034C	LYS1______	+1.07	297593	317100	lysine biosynthesis	saccharopine dehydrogenase
YJR094C	IME1______	+1.27	159484	202786	meiosis	transcription factor
YKR090W	__________	+1.13	154964	174577	unknown	unknown
YLR245C	CDD1______	+1.21	98712	119603	pyrimidine metabolism	cytidine deaminase
YML114C	TAF65_____	-1.04	351764	337280	transcription	TFIID subunit
YNL030W	HHF2______	+1.09	10119596	10988906	chromatin structure	histone H4
YNR069C	__________	-1.11	218400	196652	unknown	unknown
YOR146W	__________	-1.56	537329	345213	unknown	unknown
YPL124W	NIP29_____	-1.03	235157	229418	nuclear protein targeting	spindle pole body associated protein
YAL040C	CLN3______	+1.02	395403	404117	cell cycle	G1/S cyclin
YBR207W	FTH1______	-1.07	267800	250020	unknown	unknown; similar to Ftr1p
YDR078C	__________	-1.06	174144	163733	unknown	unknown
YDR445C	__________	+1.05	264973	278397	unknown	unknown
YGL138C	__________	+1.15	94307	108771	unknown	unknown
YGR245C	SDA1______	-1.24	889411	714514	cytoskeleton (putative)	unknown
YIL041W	__________	+1.04	1491077	1546772	unknown	unknown
YJL139C	YUR1______	+1.07	149363	159589	protein glycosylation	mannosyltransferase
YKL135C	APL2______	+1.12	137554	154674	secretion	AP-1 complex subunit
YLR069C	MEF1______	-1.04	212909	205221	protein synthesis	translation elongation factor G, mitochondrial
YLR439W	MRPL4_____	-1.07	400089	373518	protein synthesis	ribosomal protein, mitochondrial L4
YMR173W	DDR48_____	+1.57	1328330	2090544	unknown	induced by DNA damage, heat shock, or osmotic stress
YNL230C	ELA1______	-1.02	204286	199830	transcription (putative)	elongin A homolog
YOL134C	__________	+1.06	296807	313882	unknown	unknown
YOR344C	TYE7______	+1.09	549630	596518	glycolysis	basic h-l-h transcription factor
YPR041W	TIF5______	-1.20	1913551	1598172	protein synthesis	translation initiation factor eIF5
YBR019C	GAL10_____	-1.01	123000	121663	galactose metabolism	UDP-glucose 4-epimerase
YCL042W	__________	-1.05	120313	114673	unknown	unknown
YDL136W	RPL35B____	-1.00	3146978	3143614	protein synthesis	ribosomal protein L35B
YDR261C	EXG2______	-1.02	416411	408146	cell wall biogenesis	exo-beta-1,3-glucanase
YEL041W	__________	-1.09	134072	122901	unknown	unknown; similar to Fre2p
YGR059W	SPR3______	+1.23	102590	125825	sporulation	septin
YHR074W	__________	+1.05	459092	483852	unknown	unknown; similar to Rhodobacter protein adgA and Bacillus subtilis NH3-dependent NAD synthetase (spore outgrowth factor)
YJR105W	__________	-1.02	2093415	2053066	unknown	unknown; similar to ribokinase
YKR102W	FLO10_____	+1.10	140355	154733	unknown	unknown; similar to flocculation protein Flo1p
YML125C	__________	-1.28	1284667	1002197	unknown	unknown; similar to NADH-cytochrome b5 reductase
YNL040W	__________	-1.81	324373	179466	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOR158W	PET123____	-1.01	456123	453402	protein synthesis	ribosomal protein, mitochondrial small subunit
YPL136W	__________	-1.03	131848	127574	unknown	unknown
YAL053W	__________	+1.49	274214	408927	unknown	unknown
YBR219C	__________	+1.06	326985	347086	unknown	unknown
YDR090C	__________	-1.20	222602	185217	unknown	unknown; similar to Yro2p
YDR457W	TOM1______	+1.05	112804	118201	cell cycle, G2/M	unknown
YER148W	SPT15_____	-1.16	1401580	1209282	transcription	TFIID and TFIIIB subunit
YGL150C	INO80_____	+1.21	148955	180330	unknown	unknown; similar to the Snf2p family of DNA-dependent ATPases
YGR257C	__________	+1.05	351750	370102	unknown	unknown; similar to members of the mitochondrial carrier
YIL053W	RHR2______	-1.09	6800112	6228824	glycerol metabolism	DL-glycerol-3-phosphatase
YJL151C	__________	+1.53	868260	1324890	unknown	unknown
YKL147C	__________	+1.10	130164	143218	unknown	unknown
YLR081W	GAL2______	+1.08	121266	130992	transport	glucose and galactose permease
YLR451W	LEU3______	-1.05	172114	163582	leucine biosynthesis	transcription factor
YMR184W	__________	+1.77	260931	461902	unknown	unknown
YNL242W	SPO72_____	-1.01	120008	118249	sporulation	unknown
YOL146W	__________	+1.18	395444	468089	unknown	unknown
YOR356W	__________	-1.06	123834	116698	unknown	unknown; similar to human electron transfer flavoprotein-ubiquinone oxidoreductase
YPR053C	__________	+1.08	941284	1012660	unknown	unknown
YBR031W	RPL4A_____	-1.49	12310330	8235090	protein synthesis	ribosomal protein L4A
YCL054W	SPB1______	-1.37	275134	200250	ribosome biogenesis	rRna methyltransferase (putative)
YDL148C	__________	-1.29	382783	297461	unknown	unknown
YDR269C	__________	-1.05	130637	124977	unknown	unknown
YEL053C	MAK10_____	-1.22	302027	248000	dsRNA virus propagation	unknown
YGR071C	__________	+1.06	144190	152185	unknown	unknown
YHR085W	__________	+1.30	93792	121542	unknown	unknown
YJR117W	STE24_____	+1.03	667725	688271	protein processing	zinc metalloprotease; a-factor precursor processing
YLR265C	__________	+1.17	206299	241367	unknown	unknown
YMR004W	MVP1______	-1.09	291431	267283	vacuolar protein targeting	peripheral Golgi membrane protein
YNL052W	COX5A_____	-1.03	1458578	1422546	oxidative phosphorylation	cytochrome-c oxidase subunit Va
YOR170W	__________	+1.12	369152	414577	unknown	unknown
YPL148C	PPT2______	+1.10	178095	195608	lipid transport	phosphopantetheine
YAL064W	__________	+1.13	91238	103013	unknown	unknown
YBR231C	AOR1______	-1.11	186902	168126	osmotic stress response (putative)	unknown
YDR100W	__________	+1.15	298339	343585	unknown	unknown
YDR469W	__________	+1.18	329181	387266	unknown	unknown; similar to C. elegans dpy-30 gene product,
YER159C	BUR6______	+1.53	624339	955148	transcription	general pol II repressor
YGL162W	SUT1______	+1.11	143574	159362	transport	hypoxic gene family (sterol uptake)
YGR269W	__________	+1.16	94625	110137	unknown	unknown
YIL065C	MDV2______	+1.22	231223	281460	unknown	unknown
YJL163C	__________	+1.13	133843	150980	unknown	unknown; similar to bovine prefoldin subunit 1
YKL159C	RCN1______	+1.38	182232	252294	signaling	unknown; calcineurin regulator
YLR093C	NYV1______	+1.60	509267	813835	vacuolar protein targeting	vacuolar v-SNARE
YLR463C	__________	-1.04	201195	193294	unknown	unknown; similar to other subtelomerically-coded proteins
YMR195W	ICY1______	+1.49	249810	372539	cytoskeleton (putative)	unknown
YNL254C	__________	-1.17	175626	150560	unknown	unknown
YOL158C	ENB1______	-1.12	317230	283617	transport	enterobactin transporter
YOR368W	RAD17_____	-1.03	298914	291126	cell cycle, checkpoint	3'->5' exonuclease (putative)
YPR065W	ROX1______	-1.06	108618	102928	transcription, oxygen-dependent	transcriptional repressor
YBR043C	__________	-1.02	128640	126737	unknown	major facilitator superfamily
YCL066W	HMLALPHA1_	+1.05	468885	490180	transcription	silenced copy at HML; see YCR040W
YDL160C	DHH1______	-1.27	253292	198737	transcription	RNA helicase
YDR281C	PHM6______	+1.42	136759	194732	phosphate metabolism (putative)	unknown
YEL064C	__________	+1.00	143100	143661	unknown	unknown; similar to members of the major facilitator
YGR083C	GCD2______	-1.09	758986	698726	protein synthesis	translation initiation factor eIF2B subunit
YHR097C	__________	+1.45	286102	415976	unknown	unknown
YJR129C	__________	-1.03	278173	270814	unknown	unknown
YLR277C	YSH1______	-1.02	218630	215371	mRNA 3'-end processing	cleavage/polyadenylation factor CF II component
YMR016C	SOK2______	-1.17	291662	249308	unknown	unknown; similar to several transcription factors
YNL062C	GCD10_____	-1.35	443884	327812	protein synthesis	translation initiation factor eIF3 RNA-binding subunit
YOR182C	RPS30B____	+1.07	5813350	6201176	protein synthesis	ribosomal protein S30B
YPL160W	CDC60_____	-1.04	140798	135954	protein synthesis	tRNA synthetase, leucyl
YAR014C	__________	-1.05	286806	272366	unknown	unknown
YBR243C	ALG7______	-1.01	278798	276106	protein glycosylation	UDP-N-acetyl-glucosamine-1-P transferase (GPT)
YDR112W	__________	-1.01	101719	100730	unknown	unknown
YDR481C	PHO8______	+1.42	218293	309675	phosphate metabolism	vacuolar alkaline phosphatase
YER168C	CCA1______	-1.15	444584	384953	tRNA processing	tRNA nucleotidyltransferase
YGL174W	__________	+1.06	208670	220390	unknown	unknown
YGR281W	YOR1______	+1.07	313333	335123	transport	ATP-binding cassette (ABC) family
YIL074C	SER33_____	+1.20	847553	1018226	serine biosynthesis	3-phosphoglycerate dehydrogenase
YJL175W	__________	-1.08	172321	159164	unknown	unknown
YKL171W	__________	+1.19	126034	149845	unknown	putative protein kinase
YLR105C	SEN2______	+1.10	256702	282230	tRNA splicing	splicing endonuclease subunit
YMR207C	HFA1______	-1.15	316215	275716	unknown	unknown; similar to acetyl-coenzyme A carboxylase
YNL266W	__________	+1.18	272476	320843	unknown	unknown; similar to NADH dehydrogenases
YOR004W	__________	-1.39	1147861	826912	unknown	unknown
YOR380W	__________	+1.05	169091	177624	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YPR077C	__________	+1.12	129082	144226	unknown	unknown
YBR055C	PRP6______	-1.07	231166	216966	mRNA splicing	U4/U6 snRNP protein
YCLX05C	__________	-1.08	227580	211702
YDL172C	__________	+1.44	460237	664670	unknown	unknown
YDR293C	SSD1______	+1.12	187949	209889	drug resistance	putative protein phosphatase
YGR095C	RRP46_____	-1.07	589943	553378	rRNA processing	3'->5' exoribonuclease
YHR109W	CTM1______	-1.06	213669	200817	proteim modification	cytochrome c trimethylase
YJR141W	__________	+1.03	256664	265440	unknown	unknown
YLR288C	MEC3______	+1.08	164308	177102	DNA repair; DNA damage checkpoint	activates exonuclease
YMR028W	TAP42_____	+1.04	427255	443644	signaling	associated with protein phosphatases
YNL074C	MLF3______	+1.01	370600	373105	unknown	unknown
YPL172C	COX10_____	-1.19	184820	154825	respiration	cytochrome-c oxidase assembly
YAR035W	YAT1______	+1.01	111885	112899	fatty acid transport	carnitine O-acetyltransferase
YBR255W	__________	-1.04	157163	150838	unknown	unknown
YDR124W	__________	+1.01	165060	166943	unknown	unknown
YDR493W	__________	-1.01	179467	177011	unknown	unknown
YER179W	DMC1______	+1.06	144862	153458	meiosis, chromsome pairing	unknown
YGL186C	__________	-1.10	311770	283181	unknown	unknown; similar to Fcy21p, Fcy2p, Fcy22p
YGR293C	__________	-1.10	174062	158207	unknown	unknown
YIL085C	KTR7______	-1.04	581917	559921	protein glycosylation	putative mannosyltransferase
YJL187C	SWE1______	+1.04	225587	234978	cell cycle	negative regulator of Cdc28p
YKL183W	__________	-1.13	161130	142865	unknown	unknown
YLR117C	CLF1______	+1.16	167624	193890	mRNA splicing; cell cycle (putative)	unknown; synthetic lethal with cdc40

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YMR219W	ESC1______	+1.01	444617	450759	silencing	unknown
YNL278W	__________	+1.02	251619	255760	unknown	unknown
YOR016C	ERP4______	-1.01	118420	117714	membrane trafficking; secretion (putative)	unknown
YOR392W	__________	-1.10	117570	106851	unknown	unknown
YPR089W	__________	-1.29	145888	112798	unknown	unknown
YBR067C	TIP1______	-1.33	892051	669924	stress response (putative)	cell wall mannoprotein
YCR005C	CIT2______	+1.20	192354	230069	glyoxylate cycle	peroxisomal citrate synthase
YDL184C	RPL41A____	+1.17	11516947	13436264	protein synthesis	ribosomal protein L41A
YDR305C	HNT2______	+1.08	299505	323558	unknown	histidine triad family
YER008C	SEC3______	-1.08	1215829	1122077	secretion	exocyst complex subunit
YGR107W	__________	+1.11	282218	313540	unknown	unknown
YHR121W	__________	+1.17	901695	1055305	unknown	unknown
YJR153W	PGU1______	-1.20	204916	171451	unknown	endo-polygalacturonase
YLR300W	EXG1______	+1.88	2378933	4474794	cell wall biogenesis	exo-beta-1,3-glucanase
YMR039C	SUB1______	-1.11	489331	439022	transcription	transcriptional coactivator
YNL086W	__________	+1.08	180630	194354	unknown	unknown
YOR204W	DED1______	-1.86	806803	433881	RNA processing	ATP-dependent RNA helicase
YBL005W	TY1B______	-1.07	97642	90924	unknown	unknown
YBR267W	__________	-1.09	373829	341601	unknown	unknown
YDL006W	PTC1______	-1.02	342492	336973	tRNA splicing	protein phosphatase
YDR136C	__________	-1.03	94863	92279	unknown	unknown
YDR505C	PSP1______	+1.01	108617	109557	unknown	unknown; overexpression suppresses mutation in pol3
YFL004W	PHM1______	+1.08	419126	452522	phosphate metabolism (putative)	polyphosphate synthetase (putative)
YGL198W	__________	+1.10	286123	313990	unknown	unknown; similar to NADH-ubiquinone oxidoreductase chain 2
YHL005C	__________	+1.04	112627	117360	unknown	unknown
YIL097W	__________	+1.09	153400	166527	unknown	unknown
YJL199C	__________	+1.10	122118	134787	unknown	unknown
YKL195W	__________	+1.16	88338	102082	unknown	unknown
YLR129W	DIP2______	-1.13	368916	327390	unknown	interacts with Dom3p
YML006C	GIS4______	+1.02	290701	297262	unknown	unknown
YMR231W	PEP5______	-1.02	218140	213382	vacuole biogenesis	unknown; vacuolar peripheral membrane protein
YNL288W	__________	-1.15	389817	337946	unknown	unknown
YOR028C	CIN5______	-1.24	198518	160415	salt tolerance	basic leu zipper transcription factor
YPL006W	NCR1______	+1.04	110452	114596	sterol metabolism (putative)	unknown
YPR101W	SNT309____	+1.28	390460	500334	mRNA splicing	spliceosome-associated protein
YBR079C	RPG1______	-1.31	1007430	771563	protein synthesis	translation initiation factor eIF3
YCR017C	__________	-1.01	108552	106990	unknown	unknown
YDL196W	__________	-1.00	121990	121798	unknown	unknown
YER019W	__________	+1.05	1234920	1295700	unknown	unknown; similar to mammalian neutral
YGL006W	PMC1______	+1.05	324575	339428	transport	vacuolar Ca(2+)-ATPase
YGR117C	__________	-1.04	292139	280596	unknown	unknown
YHR132C	ECM14_____	-1.21	506296	418947	cell wall biogenesis	unknown
YJL006C	CTK2______	+1.03	200565	206917	transcription	cyclin-like
YKL006C	SFT1______	+1.35	316726	428996	secretion	intra-Golgi v-SNARE
YLL006W	MMM1______	-1.05	190680	181581	mitochondrial biogenesis	(putative) component of actin binding protein complex
YLR312C	__________	+1.01	93687	94388	unknown	unknown
YNL098C	RAS2______	+1.13	715148	804838	signaling, Ras pathway	GTP-binding protein, ras homolog
YOL006C	TOP1______	-1.07	192569	180109	DNA replication	topoisomerase I
YOR216C	RUD3______	-1.15	404038	351331	secretion (putative)	unknown; suppresses uso1-1
YPL195W	APL5______	-1.07	158640	147965	vacuolar protein targeting	AP-3 complex subunit
YAR062W	__________	-1.16	164045	140853	unknown	unknown; similar to the N-terminus of Flo1p, identical to Yhr213p
YBL016W	FUS3______	-1.27	297140	234521	mating (cell cycle arrest)	protein kinase
YBR279W	PAF1______	-1.05	364009	346704	transcription	RNA polymerase II-associated protein
YDL018C	ERP3______	+1.11	227997	253250	membrane trafficking; secretion (putative)	unknown
YDR148C	KGD2______	-1.02	352592	346962	TCA cycle	2-oxoglutarate dehydrogenase
YDR517W	GRH1______	-1.07	323802	302912	unknown	unknown; homolog of mammalian Golgi protein GRASP65
YGL210W	YPT32_____	+1.02	635536	647043	secretion	ras-like GTPase
YHL014C	YLF2______	+1.00	270304	270891	unknown	unknown; similar to B. subtilis GTP-binding protein and human glycogen phosphorylases
YIL108W	__________	+1.23	240555	295259	unknown	unknown
YJL211C	__________	+1.10	131591	144728	unknown	unknown
YKL207W	__________	-1.15	617364	534755	unknown	unknown
YLR141W	RRN5______	-1.05	160808	153403	transcription	component of upstream activation factor complex (UAF)
YML015C	TAF40_____	-1.15	277141	241003	transcription	TFIID 40 kD subunit
YMR243C	ZRC1______	-1.34	1518219	1133919	zinc and cadmium ion homeostasis	unknown
YNL300W	__________	-1.05	361053	343107	unknown	unknown; similar to Mid2p
YOR040W	GLO4______	-1.04	223495	215852	methylglyoxal resistance	glyoxalase II
YPL018W	CTF19_____	-1.07	158680	148587	mitosis, chromosome segregation	kinetochore protein
YPR113W	PIS1______	-1.01	1340204	1327144	phospholipid metabolism	phosphatidylinositol synthase
YBR090C	NHP6B_____	+1.17	586649	685987
YCR027C	RSG1______	-1.04	152561	146149	unknown	GTP-binding protein, ras family
YDL208W	NHP2______	-1.42	1950746	1378141	unknown	unknown; similar to high mobility group proteins
YDR327W	__________	+1.07	668811	713192	unknown	unknown
YER030W	__________	-1.18	551727	467262	unknown	unknown
YGL018C	JAC1______	-1.13	223411	197887	protein folding	chaperonin; E. coli Hsc20 homolog
YGR129W	SYF2______	+1.01	201449	202723	cell cycle (putative)	unknown; synthetic lethal with cdc40
YHR143W	RPC10_____	+1.04	684204	712498	transcription	shared subunit of RNA polymerase I,II, and III
YJL018W	__________	-1.06	136800	129381	unknown	unknown
YKL017C	HCS1______	-1.01	174981	173939	DNA replication	DNA helicase A
YLL018C	DPS1______	-1.15	2004550	1742656	protein synthesis	tRNA synthetase, aspartyl
YLR323C	__________	-1.00	154266	153758	unknown	unknown
YNL110C	__________	-1.22	947117	775881	unknown	unknown
YOL018C	TLG2______	-1.09	261584	238913	endocytosis	trans-Golgi network t-SNARE
YOR228C	__________	-1.06	143784	135301	unknown	unknown
YPL207W	__________	-1.36	449896	331456	unknown	unknown
YBL028C	__________	-1.28	662343	516974	unknown	unknown
YBR291C	CTP1______	-1.27	330866	260269	transport	mitochondrial citrate transporter
YDL030W	PRP9______	-1.10	237396	214952	mRNA splicing	U2 snRNP activation
YDR160W	SSY1______	-1.08	156955	145414	transport	regulator of transporters
YDR529C	QCR7______	+1.14	910195	1040822	respiration	cytochrome-c reductase subunit
YFL023W	__________	-1.09	155546	143224	unknown	unknown
YGL222C	EDC1______	+1.23	113439	139547	mRNA processing	unknown; genetic interactiosn with dcp1-2
YHL026C	__________	+1.17	250231	293620	unknown	unknown
YIL120W	QDR1______	+1.06	148304	156681	drug resistance (putative)	unknown; major facilitator superfamily
YJL223C	PAU1______	+1.14	253328	288470	unknown	unknown; similar to members of the Srp1p/Tip1p family
YKL219W	COS9______	+1.35	204547	277064	unknown	unknown; similar to subtelomerically-encoded proteins
YLR153C	ACS2______	-1.13	1024417	903022	acetyl-CoA biosynthesis	acetyl-coenzyme A synthetase
YML027W	YOX1______	+1.03	185721	191746	unknown	binds leu-tRNA gene
YMR255W	GFD1______	-1.03	218405	212500	RNA processing (putative)	unknown; affects DEAD box protein activity
YNL312W	RFA2______	-1.05	458094	434230	DNA replication	replication factor A 36 kD subunit
YOR052C	__________	+1.46	184458	268539	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YPL030W	__________	-1.19	381878	320381	unknown	unknown
YPR125W	__________	-1.48	1034860	699306	unknown	suppresses mrs2-1
YBR101C	__________	-1.25	957265	764424	unknown	unknown; similar to Ypt/Rab interacting protein
YCR038C	BUD5______	-1.16	152517	131283	bud site selection	GDP/GTP exchange factor for Rsr1p/Bud1p
YDL220C	CDC13_____	-1.07	113227	106126	cell cycle, G2/M	telomere binding protein
YDR339C	__________	-1.07	589735	552918	unknown	unknown
YER041W	__________	-1.11	140422	126175	unknown	unknown; similar to DNA repair protein Rad2p
YGL030W	RPL30_____	-1.13	3118889	2754211	protein synthesis	ribosomal protein L30
YGR141W	__________	+1.09	165898	181213	unknown	unknown
YHR154W	ESC4______	+1.11	152284	168403	silencing	unknown
YJL030W	MAD2______	+1.26	228904	288706	mitosis	unknown; spindle-assembly checkpoint
YKL029C	MAE1______	-1.08	255028	236850	pyruvate metabolism	mitochondrial malic enzyme
YLL030C	__________	+1.21	92089	111422	unknown	unknown; similar to Ca++-transporting ATPase
YLR335W	NUP2______	-1.03	440257	428164	nuclear protein targeting	nuclear pore protein
YMR072W	ABF2______	+1.34	742198	994571	mitochondrial genome maintenance	(putative) HMG transcription factors
YNL122C	__________	+1.08	291337	316044	unknown	unknown
YOL030W	__________	+1.19	983557	1167738	unknown	unknown; similar to Gas1p
YOR240W	__________	-1.19	612382	515607
YPL219W	PCL8______	+1.00	199517	200325	cell cycle	cyclin (Pho85p)
YER190W	YRF1-2____	-1.08	119099	109771	unknown	Y' helicase (subtelomerically-encoded)
YBL040C	ERD2______	+1.34	288692	386177	ER protein retention	HDEL receptor
YDL042C	SIR2______	-1.01	102289	101170	silencing	reulator of silencing at HML, HMR, telomeres
YDR541C	__________	-1.01	173061	171388	unknown	unknown; similar to dihydroflavonol-4-reductases
YGL233W	SEC15_____	+1.16	212461	246060	secretion	exocyst complex subunit
YHL037C	__________	+1.03	111684	114676	unknown	unknown
YIL132C	__________	-1.03	126786	122718	unknown	unknown
YJR010C	SPC1______	+1.21	258974	314342	secretion	signal peptidase subunit
YKR006C	MRPL13____	+1.05	491216	516432	protein synthesis	ribosomal protein, mitochondrial L13
YLR163C	MAS1______	-1.09	319191	292895	protein processing	mitochondrial processing protease subunit
YML037C	__________	-1.03	128572	124313	unknown	unknown
YMR267W	PPA2______	-1.09	153663	140940	oxidative phosphorylation	inorganic pyrophosphatase, mitochondrial
YNL324W	__________	-1.11	114749	103617	unknown	unknown
YOR064C	YNG1______	-1.08	380108	351201	chromatin structure	histone acetyltransferase complex subunit
YPL042C	SSN3______	-1.24	161058	130161	transcription	RNA polymerase II mediator subunit
YPR137W	RRP9______	-1.32	557004	421708	rRNA processing	U3 snRNP protein
YBR112C	CYC8______	-1.05	143229	135768	transcription	general repressor
YCR050C	__________	-1.01	173488	171424	mitochondrial function (putative)	unknown
YDL232W	OST4______	+1.08	140548	152093	protein glycosylation	oligosaccharyltransferase complex assembly
YDR351W	SBE2______	+1.13	229983	260278	bud growth	unknown
YER051W	__________	+1.01	162415	163387	unknown	unknown
YGL042C	__________	+1.05	535228	564319	unknown	unknown; similar to rat Na+/Ca++ exchanger NCX2 PIR:A54139
YGR153W	__________	+1.26	146586	184209	unknown	unknown
YHR166C	CDC23_____	-1.02	218101	214756	mitosis	anaphase promoting complex subunit
YJL043W	__________	+1.01	128360	129955	unknown	unknown
YKL040C	NFU1______	+1.04	525877	545733	iron homeostasis	unknown; similar to Anabaena nitrogen fixing protein nifU
YLL042C	APG10_____	+1.16	130715	152261	autophagy	unknown; protein conjugating enzyme (putative)
YLR347C	KAP95_____	-1.21	237884	195835	nuclear protein targeting	beta-karyopherin
YMR083W	ADH3______	-2.00	5816183	2911806	glycolysis	alcohol dehydrogenase III, mitochondrial
YNL134C	__________	+1.40	609224	851208	unknown	unknown; similar to C. carbonum toxD gene
YOL042W	__________	-1.04	271486	262104	unknown	unknown; similar to Ccr4p
YOR252W	__________	-1.01	711229	706218	unknown	unknown
YPL231W	FAS2______	-1.21	173279	142679	fatty acid metabolism	fatty-acyl-CoA synthase, alpha subunit
YBL052C	SAS3______	-1.01	180985	179651	silencing	unknown
YDL054C	__________	-1.03	171359	166954	unknown	unknown
YDR181C	SAS4______	-1.11	212705	192179	silencing	unknown
YFL045C	SEC53_____	+1.02	3170987	3225324	protein glycosylation	phosphomannomutase
YGL245W	__________	-1.07	2349721	2195065	protein synthesis	tRNA synthetase, glutamyl
YHL048W	COS8______	+1.30	537607	701228	unknown	unknown; similar to subtelomerically-encoded proteins
YIL144W	TID3______	+1.03	243102	249352	cytoskeleton	spindle pole body component
YJR022W	LSM8______	+1.22	167958	205246	mRNA splicing	snRNP protein (putative)
YKR018C	__________	-1.06	281180	266308	unknown	unknown
YLR175W	CBF5______	-1.15	2903532	2533790	mitosis	centromeric microtubule binding protein
YML047C	__________	-1.10	124158	113333	unknown	unknown
YMR279C	__________	-1.14	176726	155130	unknown	major facilitator superfamily
YNL336W	COS1______	+1.09	123213	133777	unknown	unknown; similar to subtelomerically-encoded proteins
YOR076C	__________	-1.08	273215	253630	unknown	unknown
YPL054W	LEE1______	+1.18	142122	168398	unknown	unknown
YPR147C	__________	-1.03	133408	129883	unknown	unknown
YBR124W	__________	+1.01	96877	98232	unknown	unknown
YCR062W	__________	-1.08	179230	165875	unknown	unknown
YDL244W	THI13_____	-1.00	135103	134849	unknown	unknown; similar to Thi5p, Thi11p, and Thi12p
YDR363W	ESC2______	-1.11	149903	134942	silencing	unknown
YER061C	CEM1______	-1.16	179682	155242	fatty acid metabolism	beta-keto-acyl-ACP synthase, mitochondrial
YGL054C	ERV14_____	-1.10	981805	891819	polarized growth (putative)	unknown; ER-derived vesicle protein
YHR178W	STB5______	+1.08	139749	150281	transcription	unknown; binds Sin3p
YJL055W	__________	+1.07	626988	670241	unknown	unknown
YKL052C	__________	+1.19	387201	460839	unknown	unknown
YLL054C	__________	+1.21	92695	111808	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YLR359W	ADE13_____	-1.25	3104167	2476866	purine biosynthesis	adenylosuccinate lyase
YMR094W	CTF13_____	-1.07	154509	144724	mitosis	kinetochore protein complex subunit
YNL146W	__________	+1.06	131377	139789	unknown	unknown
YOL053C	__________	+1.37	126852	173838
YOR264W	__________	+1.09	393562	427665	unknown	unknown
YPL243W	SRP68_____	-1.12	994210	890241	secretion	signal recognition particle subunit
YBL064C	__________	+1.17	240026	281312	unknown	unknown; similar to Tsa1p
YDL066W	IDP1______	+1.04	178184	186115	TCA cycle	isocitrate dehydrogenase (NADP+)
YDR193W	__________	-1.00	106055	105644	unknown	unknown
YFL057C	__________	+1.07	101947	108957	unknown	putative aryl-alcohol reductase
YGL257C	MNT2______	+1.01	286531	288668	protein glycosylation	mannosyltransferase
YHR008C	SOD2______	+1.12	95358	106993	oxidative stress response	Manganese superoxide dismutase
YIL156W	UBP7______	+1.03	201326	208232	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YJR033C	RAV1______	-1.07	440123	412056	vacuolar acidification (putative)	unknown; regulates V-ATPase
YKR030W	__________	+1.12	480688	539332	unknown	unknown
YLR187W	__________	-1.01	129307	128657	unknown	unknown
YML057W	CMP2______	+1.12	347295	390557	signaling	calcineurin catalytic A subunit
YNR009W	__________	+1.06	299863	319202	unknown	unknown
YOR088W	__________	+1.04	423385	440437	unknown	unknown
YPL064C	__________	+1.05	404384	423102	unknown	unknown
YBR136W	MEC1______	+1.14	90842	103828	DNA repair and recombination	PI kinase homolog
YCR073C	SSK22_____	+1.06	145195	153530	signaling, high osmolarity pathway	MAPKKK (mitogen-activated protein kinase kinase kinase)

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDR008C	__________	+1.16	416092	482807	unknown	unknown
YDR373W	FRQ1______	+1.13	554932	625670	unknown	unknown; similar to human BDR-1 protein and other calcium
YER070W	RNR1______	-1.10	505254	459222	DNA replication	ribonucleotide reductase
YGL066W	__________	+1.10	110770	121742	unknown	unknown; similar to Dictyostelium discoideum G-box-binding
YGR173W	__________	-1.15	1038113	900587	unknown	unknown; similar to human GTP-binding protein PIR:A55014
YHR190W	ERG9______	-1.23	1430969	1159599	sterol metabloism	squalene synthetase
YJL067W	__________	+1.14	233394	265948	unknown	unknown
YKL064W	MNR2______	+1.09	168737	184309	manganese resistance	unknown
YLL066C	__________	+1.09	102707	112235	unknown	unknown; similar to other subtelomerically-encoded proteins
YLR371W	ROM2______	-1.14	627631	551082	signaling	GDP/GTP exchange factor for Rho1p
YMR106C	YKU80_____	-1.07	150185	140084	DNA repair	DNA binding; Ku80 homolog
YNL158W	__________	-1.32	251299	190415	unknown	unknown
YOL064C	MET22_____	-1.05	502168	479290	methionine biosynthesis	3'(2')5'-bisphosphate nucleotidase
YOR276W	CAF20_____	-1.01	2396504	2366691	protein synthesis	mRNA cap-binding protein (eIF4F) 20K subunit
YPL254W	HFI1______	-1.16	288318	248604	transcription	Ada/Gcn5 protein complex
YMR321C	__________	+1.09	1319875	1444365	unknown	unknown
YBL076C	ILS1______	-1.29	475737	369776	protein synthesis	tRNA synthetase, isoleucyl
YDL078C	MDH3______	+1.09	575632	630274	TCA cycle	malate dehydrogenase
YDR205W	__________	+1.04	180688	187528	unknown	unknown; similar to Cot1p
YFR001W	LOC1______	+1.08	846614	914796	mRNA localization	dsRNA binding protein
YGR006W	PRP18_____	-1.19	182877	153703	mRNA splicing	U5 snRNP protein
YHR020W	__________	-1.48	1638200	1108062	unknown	unknown; similar to prolyl-tRNA synthetases, putative class
YIL167W	__________	-1.21	249860	206939	gluconeogenesis	serine dehydratase
YJR045C	SSC1______	-1.79	2422722	1353468	mitochondrial protein targeting	HSP70 family, chaperonin and import motor
YKR042W	UTH1______	-1.40	5294042	3781829	aging	unknown
YLR199C	__________	+1.18	386757	457807	unknown	unknown
YML069W	POB3______	-1.16	612918	527673	DNA replication (putative)	binds DNA polymerase delta
YMR301C	ATM1______	-1.14	388485	339479	transport	regulator of mit. iron transporter
YNR021W	__________	-1.28	1737234	1360554	unknown	unknown
YOR100C	CRC1______	-1.09	138882	126840	transport	mitochondrial carnitine carrier
YPL076W	GPI2______	-1.10	204598	186694	protein processing	N-acetylglucosaminylphosphatidylinositol synthesis
YPR167C	MET16_____	+1.32	181579	239362	sulfate assimilation	3'-phosphoadenylylsulfate reductase
YBR148W	YSW1______	-1.09	161605	147716	unknown	spore specific
YCR086W	__________	+1.03	243067	250492	unknown	unknown
YDR020C	__________	-1.05	145313	138404	unknown	unknown; similar to uridine kinases and phosphoribulokinases
YDR385W	EFT2______	-1.19	5311326	4467472	protein synthesis	translation elongation factor eEF2
YER082C	__________	-1.17	655629	561306	unknown	unknown
YGL078C	DBP3______	-1.26	1160291	921940	rRNA processing	RNA helicase
YGR185C	TYS1______	-1.19	2308584	1935206	protein synthesis	tRNA synthetase, tyrosyl
YHR202W	__________	-1.07	238554	222392	unknown	unknown
YJL079C	PRY1______	+1.16	851683	991614	unknown	unknown; similar to plant PR-pathogen related proteins
YKL076C	__________	+1.09	287863	312346	unknown	unknown
YLR011W	__________	+1.19	243662	290545	unknown	unknown; similar to E. coli 20.4 KD protein of unknown function
YLR383W	RHC18_____	+1.00	116350	116689	DNA repair, recombination	unknown
YMR118C	__________	-1.12	175472	156940	unknown	unknown; similar to Sdh3p
YNL170W	__________	+1.24	525937	650646	unknown	unknown
YOL076W	MDM20_____	-1.23	288026	233423	mitochondrial inheritance; actin assembly	transmembrane protein
YOR288C	MPD1______	-1.05	258184	245828	protein folding (putative)	related to protein disulfide isomerases
YPL264C	__________	-1.12	181110	162222	unknown	major facilitator superfamily
YBL088C	TEL1______	+1.06	104182	110269	telomere length regulation	putative phosphatidylinositol kinase
YDL090C	RAM1______	-1.06	232680	220424	protein processing	farnesyltransferase
YDR213W	UPC2______	-1.06	142711	134641	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YFR013W	IOC3______	-1.07	326503	305792	unknown	unknown
YGR018C	__________	+1.31	423768	554623	unknown	unknown
YHR031C	RRM3______	-1.05	225231	215335	transposition; rDNA replication	DNA helicase
YIR001C	SGN1______	+1.01	351504	354504	unknown; growth on ethanol and glycerol	unknown
YJR057W	CDC8______	+1.09	302876	330758	DNA replication	thymidylate kinase
YKR054C	DYN1______	+1.03	96558	99585	cytoskeleton	dynein heavy chain
YLR211C	__________	+1.06	126356	133988	unknown	unknown
YML081W	__________	-1.07	681778	636418	unknown	unknown
YMR311C	GLC8______	+1.19	641724	764825	mitosis, chromosome segregation	unknown; regulates Glc7p
YNR033W	ABZ1______	-1.11	399630	359018	PABA biosynthesis	para-aminobenzoate synthase
YOR112W	__________	-1.06	223596	210865	unknown	unknown
YPL088W	__________	+2.29	232633	532072	unknown	unknown; similar to Agrobacterium tumefaciens MocA protein
YPR179C	PLO1______	-1.03	168429	163580	unknown; ploidy-related	unknown; similar to C-terminal region of Nip80p
YBR160W	CDC28_____	+1.31	456369	600030	cell cycle	cyclin dependent protein kinase
YCR097W	HMRA1_____	+1.06	134533	142606
YDR032C	PST2______	+1.26	986902	1247021	unknown	unknown; similar to Ycp4p and S. pombe OBR1 brefeldin A; secreted by regenerating protoplasts
YDR397C	NCB2______	+1.22	657589	803534	transcription	negative regulator of RNA polymerase II
YER093C	__________	-1.13	1378372	1221125	unknown	unknown
YGL090W	LIF1______	-1.14	376521	331279	DNA replication (putative)	interacts with DNA ligase
YGR197C	SNG1______	+1.02	213579	217089	nitrosoguanidine resistance	unknown
YHR214W	__________	-1.34	302123	224694	unknown	unknown
YJL091C	__________	+1.06	278406	294121	unknown	unknown; similar to Can1p
YKL088W	__________	-1.07	245547	229776	unknown	unknown; similar to Sis2p
YLR023C	__________	-1.06	213100	201763	unknown	unknown
YLR395C	COX8______	+1.33	621829	827079	oxidative phosphorylation	cytochrome-c oxidase chain VIII
YMR129W	POM152____	-1.23	702949	569583	nuclear protein targeting	nuclear pore protein
YNL182C	__________	-1.47	634983	433252	unknown	unknown
YOL088C	MPD2______	-1.14	710366	624361	unknown	putative protein disulfide isomerase
YOR299W	BUD7______	+1.15	365148	421274	bud site selection, bipolar	unknown
YPL276W	__________	-1.12	147895	132517	unknown	unknown; similar to formate dehydrogenases
YAL008W	FUN14_____	-1.00	169495	168775	unknown	unknown
YBR172C	SMY2______	-1.33	422726	318039	unknown	kinesin related
YCRX02C	__________	+1.04	90114	94036
YDR043C	NRG1______	-1.16	159847	138396	unknown	unknown; suppresses snf mutation(s)
YDR410C	STE14_____	-1.17	284063	243768	mating	a-factor farnesyltransferase
YER105C	NUP157____	+1.02	769881	784706	nuclear protein targeting	nuclear pore protein
YGL103W	RPL28_____	+1.20	14313837	17160627	protein synthesis	ribosomal protein L28
YGR210C	__________	-1.15	880663	764216	unknown	unknown
YIL007C	__________	-1.09	772397	708935	unknown	unknown
YJL104W	__________	-1.10	559461	508038	unknown	unknown
YKL100C	__________	-1.08	272972	251774	unknown	unknown
YLR408C	__________	+1.23	167636	206694	unknown	unknown
YMR141C	__________	+1.28	200333	256150	unknown	unknown
YNL195C	__________	-1.23	148418	120600	unknown	unknown
YOL101C	__________	-1.11	345519	312050	unknown	unknown
YOR311C	__________	-1.15	573320	498418	unknown	unknown
YPR006C	ICL2______	-1.03	190005	184494	unknown	isocitrate lyase, nonfunctional
YBL101C	ECM21_____	+1.05	101981	107510	cell wall biogenesis	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YCL006C	__________	+1.19	216932	257493
YDL103C	QRI1______	-1.23	455738	370874	UDP-N-acetylglucosamine biosynthesis	UDP-N-acetylglucosamine pyrophosphorylase
YDR226W	ADK1______	-1.16	3132113	2693129	metabolism	cytosolic adenylate kinase
YEL007W	__________	+1.01	140290	141671	unknown	unknown; similar to Yhr177p
YFR026C	__________	-1.06	142224	134485	unknown	unknown
YGR029W	ERV1______	+1.14	297899	340219	mitochondrial biogenesis	unknown; similar to human ALR protein
YHR043C	DOG2______	+1.36	378629	513082	2-deoxyglucose resistance	2-deoxyglucose-6-phosphate phosphatase
YIR014W	__________	+1.07	130872	139490	unknown	unknown
YJR070C	__________	-1.30	1863643	1431217	unknown	unknown
YKR067W	__________	-1.03	167939	162605	unknown	unknown; similar to Sct1p
YLR224W	__________	-1.03	316275	307320	unknown	unknown
YNL007C	SIS1______	-1.18	1099273	932102	translation	heat shock protein, homolog of E. coli DnaJ
YNR046W	__________	-1.15	1430051	1247565	unknown	unknown
YOR125C	CAT5______	-1.06	377061	356561	ubiquinone biosynthesis	unknown
YPL101W	__________	-1.18	457948	387787	unknown	unknown
YPR192W	AQY1______	-1.17	226930	194152	transport, water	aquaporin
YAL020C	ATS1______	-1.00	145574	145482	cytoskeleton (putative)	unknown; similar to human RCC1
YBR184W	__________	-1.77	340724	193014	unknown	unknown
YCRX14W	__________	-1.70	243310	143363
YDR055W	PST1______	+1.66	332322	550894	unknown	unknown; secreted by regenerating protoplasts
YDR422C	SIP1______	-1.50	278509	185480	transcription	negative regulator of GAL genes
YER117W	RPL23B____	-1.22	10428376	8544491	protein synthesis	ribosomal protein L23B
YGL115W	SNF4______	-1.12	722280	642916	glucose derepression	component of Snf1 complex
YGR222W	PET54_____	+1.30	239754	312162	protein synthesis	translation activator of COX3
YIL018W	RPL2B_____	+1.00	15698524	15733172	protein synthesis	ribosomal protein L2B
YJL116C	NCA3______	-1.22	314140	257329	ATP synthesis	regulates expression of F0F1 ATPase subunits
YKL112W	ABF1______	-1.08	285540	264543	transcription	ARS-binding factor
YLR046C	__________	+1.03	279241	286832	unknown	unknown
YLR418C	CDC73_____	-1.09	430707	393425	transcription	RNA polymerase II accessory protein
YMR153W	NUP53_____	-1.05	418102	396319	nuclear protein targeting	nuclear pore protein
YNL207W	__________	-1.09	196905	181258	unknown	unknown
YOL111C	__________	-1.09	825833	758803	unknown	unknown; similar to human ubiquitin-like protein GDX
YOR323C	PRO2______	-1.28	1800455	1408007	proline biosynthesis	gamma-glutamyl phosphate reductase
YPR018W	RLF2______	-1.04	162268	155579	chromatin structure	chromatin assembly factor I subunit
YBL111C	__________	-1.28	339105	264696	unknown	unknown
YCL019W	__________	-1.24	14105985	11330415	unknown	unknown
YDL115C	__________	-1.06	300359	283101	unknown	unknown
YEL018W	__________	-1.24	349090	282279	unknown	unknown
YFR036W	CDC26_____	-1.55	328033	211390	cell cycle	anaphase-promoting complex subunit
YHR054C	__________	-1.04	1006796	966042	unknown	unknown
YJR083C	__________	+1.04	231970	241260	unknown	unknown
YKR079C	__________	-1.13	1111837	987034	unknown	unknown
YLR234W	TOP3______	-1.02	115438	113616	DNA replication	DNA topoisomerase III
YML103C	NUP188____	-1.19	575425	482785	nuclear protein targeting	nuclear pore protein
YNL019C	__________	-1.13	153522	136160	unknown	unknown
YNR058W	BIO3______	+1.00	165031	165577	biotin biosynthesis	DAPA aminotransferase
YOR137C	__________	+1.10	187249	206549	unknown	unknown
YPL113C	__________	-1.22	171277	140194	unknown	unknown; similar to E. coli 2-hydroxyacid dehydrogenase
YPR204W	__________	-1.05	1764909	1679802	unknown	unknown; similar to other subtelomerically-encoded proteins
YAL031C	FUN21_____	-1.06	169010	159508	unknown	unknown
YBR196C	PGI1______	-1.10	2725787	2469379	glycolysis	glucose-6-phosphate isomerase
YDR067C	__________	+1.10	277924	306499	unknown	unknown
YDR434W	__________	-1.01	266225	263354	unknown	unknown
YER128W	__________	+1.00	163294	163422	unknown	unknown
YGL127C	SOH1______	+1.29	306482	395295	unknown	unknown; similar to RNA polymerases
YGR234W	YHB1______	-1.02	9660964	9451477	oxidative stress response (putative)	flavohemoglobin
YIL030C	SSM4______	-1.13	970018	856975	mRNA decay	unknown
YJL128C	PBS2______	-1.18	383639	324430	signaling	two-component pathway
YKL124W	SSH4______	-1.14	402455	351954	unknown	suppresses shr3 mutation
YLR058C	SHM2______	-1.41	946731	670152	one-carbon interconversion	serine hydroxymethyltransferase
YLR428C	__________	-1.09	147426	135594	unknown	unknown
YMR163C	__________	-1.10	174832	159058	unknown	unknown
YNL219C	ALG9______	-1.15	336871	293793	protein glycosylation	mannosyltransferase
YOL123W	HRP1______	-1.35	1017953	755013	mRNA processing	poly(A)+ RNA-binding protein, putative
YOR335C	ALA1______	-1.48	492778	331926	protein synthesis	tRNA synthetase, alanyl
YPR030W	CSR2______	-1.04	133528	128675	unknown	unknown; multicopy suppressor of chs5 spa2 double mutant
YBR010W	HHT1______	-1.08	7566888	7022163	chromatin structure	histone H3
YCL031C	RRP7______	+1.07	1066633	1137311	rRNA processing	unknown
YDL127W	PCL2______	-1.07	234514	219985	cell cycle	G1/S cyclin
YDR250C	__________	+1.05	145305	152364	unknown	unknown
YEL030W	ECM10_____	-1.16	205143	177490	cell wall biogenesis	heat shock protein (HSP70)
YFR047C	__________	+1.02	622469	634337	unknown	unknown; similar to Rhodospirillum rubrum and S. typhimurium nicotinate-nucleotide pyrophosphorylase
YGR048W	UFD1______	+1.17	201705	235975	protein degradation, ubiquitin-mediated	unknown; ubiquitin fusion degradation
YHR064C	PDR13_____	-1.35	1584474	1172232	drug resistance	HSP70 homolog
YIR035C	__________	+1.20	351384	420587	unknown	unknown; similar to proteins of the human corticosteroid
YKR091W	SRL3______	+3.14	165153	518097	unknown	unknown; suppressor of Rad53 lethality
YLR246W	ERF2______	-1.02	177801	175171	signaling (putative)	unknown; synthetic lethal with Ras CaaX mutant
YML115C	VAN1______	-1.13	436834	388247	protein glycosylation and vanadate resistance	mannosyltransferase
YNL031C	HHT2______	-1.03	7961497	7729090	chromatin structure	histone H3
YNR070W	__________	-1.17	267526	228899	unknown	unknown; ATP-binding cassette (ABC) family
YOR147W	__________	-1.06	206738	194173	unknown	unknown
YPL125W	KAP120____	-1.06	122362	115446	nuclear protein targeting	karyopherin
YAL041W	CDC24_____	+1.05	444724	466004	cell polarity	GDP/GTP exchange factor for Cdc42p
YBR208C	DUR1,2____	-1.28	417365	325340	nitrogen, amino acid, nucleotide metabolism	urea amidolyase
YDR079W	PET100____	+1.00	409734	411443	respiration	cytochrome-c oxidase assembly
YDR446W	ECM11_____	-1.25	306226	244925	cell wall biogenesis	unknown
YER138C	__________	+1.20	15958128	19077110	unknown	unknown
YGL139W	__________	-1.81	1908616	1056285	unknown	unknown
YGR246C	BRF1______	-1.45	691148	476264	transcription	TFIIIB 70 kD subunit
YIL042C	__________	-1.02	207744	204186	unknown	unknown; similar to mitochondrial branched chain
YJL140W	RPB4______	+1.09	899556	984134	transcription	RNA polymerase II 32 kDa subunit
YKL136W	__________	+1.09	139557	152592	unknown	unknown
YLR070C	__________	+1.08	132526	142877	unknown	unknown; similar to sugar dehydrogenases
YLR440C	__________	-1.10	275805	250349	unknown	unknown
YNL231C	PDR16_____	+1.02	1047990	1072347	drug resistance	unknown
YOL135C	MED7______	-1.10	332613	302587	transcription	RNA polymerase II mediator subunit
YOR345C	__________	-1.07	117622	110086	unknown	unknown
YPR042C	PUF2______	-1.02	110349	108594	unknown	mRNA binding protein
YBR020W	GAL1______	-1.13	302649	267066	galactose metabolism	galactokinase
YCL043C	PDI1______	-1.13	1303085	1150670	protein folding	protein disulfide isomerase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDL137W	ARF2______	+1.04	3449278	3593069	secretion	ADP-ribosylation factor
YEL042W	GDA1______	-1.26	538545	427382	Golgi organization	Golgi membrane guanosine diphosphatase
YGR060W	ERG25_____	-1.47	238199	162479	sterol metabolism	C-4 sterol methyl oxidase
YHR075C	PPE1______	+1.13	257152	290620	protein synthesis	ribosomal protein, mitochondrial small subunit; carboxymethyl esterase
YJR106W	ECM27_____	+1.00	135240	135360	cell wall biogenesis	unknown
YKR103W	__________	+1.03	99819	103224	unknown	ATP-binding cassette (ABC) superfamily
YML126C	ERG13_____	-1.28	2686789	2091031	sterol metabolism	3-hydroxy-3-methylglutaryl coenzyme A synthase
YNL041C	__________	+1.01	177097	178466	unknown	unknown
YOR159C	SME1______	-1.08	426345	395499	mRNA splicing	U1, U2 snRNP protein
YPL137C	__________	+1.03	146658	151668	unknown	unknown; similar to Mhp1p
YAL054C	ACS1______	+1.01	109733	110325	acetyl-CoA biosynthesis	acetyl-CoA synthetase
YBR220C	__________	-1.18	245878	208434	unknown	unknown; similar to E. coli ampG protein
YDR091C	RLI1______	-1.52	622344	409096	unknown	unknown; similar to members of the ATP-binding cassette
YDR458C	__________	-1.07	246754	230111	unknown	unknown
YGL151W	NUT1______	+1.01	105978	107022	mating type switching	negative regulator of HO endonuclease
YGR258C	RAD2______	-1.05	133192	126874	DNA repair, nucleotide excision	single-stranded DNA endonuclease
YIL054W	__________	+1.03	111774	115008	unknown	unknown
YJL152W	__________	+1.54	631820	973590	unknown	unknown
YKL148C	SDH1______	+1.14	231620	263563	TCA cycle, oxidative phosphorylation	succinate dehydrogenase flavoprotein subunit
YLR082C	SRL2______	-1.06	118990	112697	unknown	unknown; suppressor of Rad53 lethality
YLR452C	SST2______	-1.30	783112	603648	mating	negative regulator of Gpa1
YMR185W	__________	-1.03	240673	232827	unknown	unknown
YNL243W	SLA2______	-1.11	849437	766945	cytoskeleton	talin-like protein
YOL147C	PEX11_____	+1.04	464860	482500	peroxisome biogenesis	peripheral membrane protein
YOR357C	GRD19_____	+1.13	460278	521664	secretion	Golgi protein retention
YPR054W	SMK1______	-1.06	146855	138395	sporulation	MAP kinase
YBR032W	__________	+1.10	160480	176420	unknown	unknown
YCL055W	KAR4______	-1.01	234397	231579	karyogamy	transcription factor
YDL149W	APG9______	-1.02	173783	170078	autophagy	unknown; integral membrane protein
YDR270W	CCC2______	-1.01	182093	179584	oxidative phosphorylation	Cu(2+)-transporting ATPase
YEL054C	RPL12A____	-1.26	14308887	11356593	protein synthesis	ribosomal protein L12A
YGR072W	UPF3______	+1.03	321311	330731	mRNA decay, nonsense-mediated	unknown
YHR086W	NAM8______	+1.12	188089	210539	RNA splicing, mitochondrial	RNA binding protein
YJR118C	ILM1______	+1.12	544091	611594	mitochondrial genome maintenance (putative)	unknown
YLR266C	__________	+1.09	165527	180796	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YMR005W	MPT1______	-1.13	505198	447278	protein synthesis	unknown
YNL053W	MSG5______	+1.08	268489	289146	signaling, pheromone pathway	dual-specificity protein phosphatase
YOR171C	LCB4______	-1.07	377707	351870	sphingolipid metabolism	long chain base kinase
YPL149W	APG5______	+1.29	351926	452658	autophagy	unknown
YAL065C	__________	+1.13	178323	202138	unknown	unknown; similar to Flo1p
YBR232C	__________	-1.15	123689	107506	unknown	unknown
YDR101C	__________	-1.36	1328188	980033	unknown	unknown
YDR470C	__________	+1.04	203339	210647	unknown	unknown; mitochondrial carrier (MCF) family
YGL163C	RAD54_____	+1.03	118616	122653	DNA repair	DNA-dependent ATPase
YGR270W	YTA7______	+1.01	127981	129169	protein degradation	26S proteasome subunit; ATPase
YIL066C	RNR3______	-1.33	210582	157877	DNA repair	repair-induced ribonucleotide reductase
YJL164C	SRA3______	+1.14	193277	219787	signaling	cAMP-dependent protein kinase subunit
YKL160W	__________	+1.07	1152063	1229169	unknown	unknown
YLR094C	GIS3______	-1.07	245822	228727	unknown	unknown
YLR464W	__________	-1.28	309305	241724	unknown	unknown; similar to other subtelomerically-coded proteins
YMR196W	__________	-1.14	809607	709248	unknown	unknown
YNL255C	GIS2______	-1.05	3268592	3115408	unknown	unknown; gig3 suppressor
YOL159C	__________	+1.76	315055	554679	unknown	unknown; similar to Ovis aries melatonin receptor
YOR369C	RPS12_____	+1.20	15958128	19127806	protein synthesis	ribosomal protein S12
YPR066W	UBA3______	+1.05	474747	496526	protein degradation, Rub1p-mediated	Rub1p activating protein
YBR044C	TCM62_____	+1.01	163397	164853	protein folding	chaperone, mitochondrial (putative)
YCL067C	HMLALPHA2_	+1.30	685687	893222	transcription	silenced copy at HML; see YCR039C
YDL161W	ENT1______	-1.06	587636	555683	endocytosis (putative)	unknown; epsin homolog
YDR282C	__________	-1.11	183774	164964	unknown	unknown
YEL065W	SIT1______	+1.11	223361	247447	transport	Ferrioxamine B permease
YGR084C	MRP13_____	-1.20	343621	285878	protein synthesis	ribosomal protein, mitochondrial small subunit
YHR098C	SFB3______	-1.25	559541	448417	unknown	unknown; binds Sed3p and Sec23p
YJR130C	STR2______	-1.06	256912	243465	methionine biosynthesis	O-succinylhomoserine (thiol)-lyase
YLR278C	__________	+1.08	105999	114485	unknown	unknown; similar to transcription factors, has Zn[2]-Cys]
YMR017W	SPO20_____	-1.11	153717	138448	sporulation	SNAP 25 homolog; prospore membrane formation
YNL063W	__________	+1.01	327875	331606	unknown	unknown; similar to Mycoplasma protophorphyrinogen oxidase
YOR183W	__________	-1.08	136687	126362	unknown	unknown
YPL161C	BEM4______	-1.04	115375	111265	bud emergence	interacts with Rho-type GTPases
YAR015W	ADE1______	-1.28	2101024	1635249	purine biosynthesis	phosphoribosylaminoimidazole-succinocarboxamide synthase
YBR244W	GPX2______	-1.10	936326	847428	mitochondrial morphology; glutathione metabolism (putative)	glutathione peroxidase (putative)
YDR113C	PDS1______	-1.05	270485	258101	cell cycle	anaphase inhibitor (putative)
YDR482C	__________	+1.21	414005	500093	unknown	unknown
YER169W	RPH1______	-1.17	183218	156906	DNA repair	transcriptional repressor of PHR1
YGL175C	SAE2______	-1.04	126390	121110	meiosis, recombination	unknown
YGR282C	BGL2______	+1.32	2738055	3606927	cell wall biogenesis	endo-beta-1,3-glucanase
YIL075C	RPN2______	-1.11	717788	644080	tRNA processing	26S proteasome subunit)
YJL176C	SWI3______	-1.03	358029	348593	transcription	component of SWI/SNF global activator complex
YKL172W	EBP2______	-1.47	1566582	1062884	unknown	unknown; EBNA1-binding protein homolog
YLR106C	__________	-1.08	115529	107262	unknown	unknown; similar to Rnh70p
YMR208W	ERG12_____	-1.12	572747	511941	sterol metabolism	mevalonate kinase
YNL267W	PIK1______	-1.11	117848	106432	cytokinesis	phosphatidylinositol 4-kinase
YOR005C	DNL4______	+1.04	316183	327449	DNA repair	DNA ligase IV homologue
YOR381W	FRE3______	-1.00	127520	127066	unknown	unknown; similar to Fre2p
YPR078C	__________	+1.60	145721	232895	unknown	unknown
YBR056W	__________	+1.59	305441	486271	unknown	unknown; similar to glucan-1,3-beta-glucosidase
YCLX06C	__________	-1.23	531013	431969
YDL173W	__________	+1.24	456196	564878	unknown	unknown
YDR294C	DPL1______	-1.02	397717	390865	phospholipid metabolism	dihydrosphingosine phosphate lyase
YEL076C	__________	-1.11	190137	170533	unknown	unknown; similar to other subtelomerically-encoded proteins
YGR096W	__________	-1.11	185693	166550	unknown	unknown
YHR110W	ERP5______	+1.17	625476	731693	membrane trafficking; secretion (putative)	unknown
YJR142W	__________	+1.09	342698	373825	unknown	unknown; similar to thiamine pyrophosphokinase
YLR289W	GUF1______	-1.05	129595	123658	unknown	GTPase; similar to E. coli LepA
YMR029C	__________	-1.17	388594	330927	unknown	unknown
YNL075W	IMP4______	-1.28	706462	550699	rRNA processing	U3 snoRNP protein
YOR193W	__________	+1.18	295233	348972	unknown	unknown
YPL173W	MRPL40____	-1.13	393775	348662	protein synthesis	ribosomal protein, mitochondrial L40
YAR037W	__________	-1.36	164038	120523
YBR256C	RIB5______	+1.27	631682	802526	flavin biosynthesis	riboflavin synthase, alpha chain
YDR125C	ECM18_____	-1.14	145906	128464	cell wall biogenesis	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDR494W	__________	-1.11	324892	291881	unknown	unknown
YER180C	ISC10_____	+1.24	258820	319863	meiosis, spore formation	unknown
YGL187C	COX4______	+1.33	1078607	1429893	oxidative phosphorylation	cytochrome-c oxidase subunit IV
YGR294W	__________	+1.04	525687	546554	unknown	PAU1 unknown; family
YIL086C	__________	-1.46	278423	190339	unknown	unknown
YJL188C	__________	+1.09	14142690	15453312	unknown	unknown
YKL184W	SPE1______	-1.22	925128	759851	polyamine biosynthesis	ornithine decarboxylase
YLR118C	__________	+1.08	380829	410460	unknown	unknown
YMR220W	ERG8______	-1.28	822864	640489	sterol metabolism	phosphomevalonate kinase
YNL279W	PRM1______	-1.14	153300	134626	mating (putative)	unknown; pheromone-regulated membrane protein
YOR017W	PET127____	-1.13	354494	314923	protein synthesis	mitochondrial translation
YOR393W	ERR1______	-1.84	275504	149988	unknown	enolase homolog
YPR090W	__________	-1.18	203683	173227	unknown	unknown
YBR068C	BAP2______	-1.07	114319	106532	transport	branched-chain amino acid permease
YCR006C	__________	-1.26	141296	112346	unknown	unknown
YDL185W	TFP1______	+1.04	999501	1034577	vacuolar acidification	vacuolar H+-ATPase subunit
YDR306C	__________	-1.06	161897	152712	unknown	unknown
YER009W	NTF2______	+1.13	2426013	2733724	nuclear protein targeting	nuclear transport factor
YGR108W	CLB1______	+1.09	597540	652438	cell cycle	G2/M cyclin
YHR122W	__________	-1.11	760769	685919	unknown	unknown
YJR154W	__________	-1.13	164548	145156	unknown	unknown
YLR301W	__________	+1.03	1162617	1192388	unknown	unknown
YMR040W	__________	+1.16	167494	194963	unknown	unknown; similar to Ykl065p
YNL087W	__________	-1.29	960026	746414	unknown	unknown
YOR205C	__________	-1.23	213033	172847	unknown	unknown
YPL184C	__________	-1.11	122512	110616	unknown	unknown
YBL005W	PDR3______	-1.15	165229	144141	transport	transcription factor
YBR268W	MRPL37____	+1.01	440206	443959	protein synthesis	ribosomal protein, mitochondrial L37
YDL007W	RPT2______	+1.16	584285	680187	protein degradation	26S proteasome subunit
YDR137W	RGP1______	-1.33	260749	195831	unknown	unknown
YDR506C	__________	-1.21	137304	113760	unknown	unknown; similar to Fet5p
YFL005W	SEC4______	-1.20	354420	295826	secretion	ras-like GTPase; post-Golgi
YGL199C	__________	-1.13	268493	237881	unknown	unknown
YHL006C	__________	-1.01	159584	157380	unknown	unknown
YIL098C	FMC1______	+1.02	268677	273181	respiration (putative)	production or assembly of mitochondrial cytochromes
YJL200C	__________	-1.51	726802	482550	unknown	unknown; similar to aconitase, has potential mitochondrial
YKL196C	YKT6______	-1.04	897814	859605	secretion	ER-to-Golgi v-SNARE
YLR130C	ZRT2______	-1.21	446548	368145	transport	zinc transporter
YML007W	YAP1______	+1.05	452557	473802	oxidative stress	transcriptional activator
YMR232W	FUS2______	+1.01	233508	236781	mating; cell fusion	fus1 suppressor
YNL289W	PCL1______	-1.17	742299	635968	cell cycle	G1/S cyclin
YOR029W	__________	-1.21	149257	122939	unknown	unknown
YPL007C	TFC8______	-1.11	220862	199560	transcription	TFIIIC subunit
YPR102C	RPL11A____	+1.37	13914930	19081013	protein synthesis	ribosomal protein L11A
YBR080C	SEC18_____	-1.04	294605	282903	secretion	NSF; vesicle fusion
YCR018C	SRD1______	+1.05	89931	94604	rRNA processing	nucleolar protein
YDL197C	ASF2______	-1.16	178261	153633	transcription	anti-silencing protein
YER019C	SBH2______	-1.06	218491	205265	secretion	ER protein translocation complex subunit
YGL007W	__________	+1.03	105479	108699	unknown	unknown
YGR118W	RPS23A____	+1.21	15731037	19096247	protein synthesis	ribosomal protein S23A
YHR133C	__________	-1.04	1075426	1033301	unknown	unknown
YJL007C	__________	+1.05	208532	219585	unknown	unknown
YKL006W	RPL14A____	-1.11	12060412	10839488	protein synthesis	ribosomal protein L14A
YLL007C	__________	+1.00	311395	311920	unknown	unknown
YNL099C	__________	-1.16	552883	475304	unknown	unknown
YOL007C	CSI2______	-1.11	297657	267759	cell wall biogenesis	chitin synthase 3 subunit
YOR217W	RFC1______	-1.48	504282	340838	DNA replication	DNA replication factor C 95 KD subunit
YPL196W	__________	+1.10	319401	352641	unknown	unknown
YAR064W	__________	-1.05	120157	114408	unknown	unknown
YBL017C	PEP1______	-1.14	171734	150460	vacuolar protein targeting	CPY sorting receptor
YBR280C	__________	+1.00	125025	125577	unknown	unknown; similar to Srm1p/Prp20p
YDL019C	__________	-1.12	380436	339718	unknown	unknown; similar to Swh1p
YDR149C	__________	+1.05	124806	130677	unknown	unknown
YDR518W	EUG1______	+1.03	249352	257701	protein folding	protein disulfide isomerase
YFL014W	HSP12_____	+1.57	159498	250236	glucose and lipid utilization	heat shock protein
YGL211W	__________	-1.55	230485	149064	unknown	unknown
YHL015W	RPS20_____	-1.24	7810021	6314595	protein synthesis	ribosomal protein S20
YIL109C	SEC24_____	-1.06	619529	586752	secretion	vesicle coat component
YJL212C	OPT1______	-1.57	365105	232837	transport	oligopeptide transporter
YKL208W	CBT1______	-1.04	180480	174010	mRNA processing, COB mRNA	unknown
YLR142W	PUT1______	+1.10	112150	123268	proline utilization	proline oxidase
YML016C	PPZ1______	-1.04	232781	223190	stress response	ser/thr phosphatase
YMR244W	__________	-1.56	245908	158040	unknown	unknown; similar to Nca3p
YNL301C	RPL18B____	-1.15	12585476	10931257	protein synthesis	ribosomal protein L18B
YOR041C	__________	-1.38	301634	217899	unknown	unknown
YPL019C	PHM2______	+1.00	293907	294927	phosphate metabolism (putative)	polyphosphate synthetase (putative)
YPR114W	__________	-1.24	473503	381387	unknown	unknown
YBR090C	__________	-1.10	325117	295291	unknown	unknown
YCR028C	FEN2______	+1.03	110672	114345	unknown	unknown; similar to Dal5p and members of the allantoate
YDL209C	__________	-1.53	248515	162595	unknown	unknown
YDR328C	SKP1______	-1.22	753238	615607	mitosis	kinetochore protein
YER031C	YPT31_____	-1.51	1151684	763570	secretion	rab GTPase; intra-Golgi
YGL019W	CKB1______	-1.47	546241	372786	salt tolerance	casein kinase II subunit
YGR130C	__________	+1.00	409453	410459	unknown	unknown; similar to Entamoeba histolytica myosin heavy chain
YHR143W	__________	+1.02	421015	430556	unknown	unknown
YJL019W	__________	-1.08	155137	143509	unknown	unknown
YKL018W	__________	-1.12	324840	289857	unknown	unknown
YLL019C	KNS1______	+1.11	166464	184815	unknown	protein kinase
YLR324W	__________	+1.08	187385	201517	unknown	unknown
YMR061W	RNA14_____	-1.07	361417	337085	mRNA 3'-end processing	cleavage/polyadenylation factor CF I component
YNL111C	CYB5______	+1.03	851085	875401	lipid metabolism	cytochrome b5
YOL019W	__________	+1.12	280638	314779	unknown	unknown
YOR229W	WTM2______	-1.10	543566	494875	transcription	shared subunit of RNA polymerases I, II, and III
YPL208W	__________	-1.10	340407	310366	unknown	unknown
YBL029W	__________	+1.03	345623	356154	unknown	unknown
YBR292C	__________	-1.08	146461	135023	unknown	unknown
YDL031W	DBP10_____	-1.14	355299	310645	unknown	unknown; similar to RNA helicases
YDR161W	TCI1______	-1.36	587466	430449	unknown	interacts with PP2C
YDR530C	APA2______	-1.26	203789	161365	purine metabolism	ATP adenylyltransferase II
YFL024C	EPL1______	-1.01	110191	108699	unknown	putative chromatin protein

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YGL223C	__________	+1.03	174536	180036	unknown	unknown
YHL027W	RIM101____	+1.03	303536	313229	meiosis	transcription factor
YIL121W	__________	+1.04	158266	164051	unknown	unknown; major facilitator superfamily
YJL225C	__________	-1.04	795903	766651	unknown	unknown; similar to other subtelomerically-encoded proteins
YKL220C	FRE2______	-1.02	124108	122139	iron homeostasis	ferric (and cupric) reductase
YLR154C	__________	+1.19	239277	285425	unknown	unknown
YML028W	TSA1______	-1.31	12284231	9358036	oxidative stress response	thiol-specific
YNL313C	__________	-1.18	216148	182901	unknown	unknown
YOR053W	__________	-1.11	1648889	1488163	unknown	unknown; similar to protamines
YPL031C	PHO85_____	-1.04	576275	551662	phosphate metabolism; cell cycle; glycogen metabolism	protein kinase
YPR126C	__________	+1.05	326109	342180	unknown	unknown
YBR102C	EXO84_____	-1.13	247039	217736	secretion	exocyst complex subunit
YCR039C	MATALPHA2_	-1.04	467962	449353	transcription	a-specific gene repressor
YDL221W	__________	-1.17	230159	197048	unknown	unknown
YDR340W	__________	-1.10	3345421	3047140	unknown	unknown; similar to Cyc1/Cyp3 transcription activator
YER042W	MXR1______	+1.48	671600	996845	oxidative stress response	peptide-methionine sulfoxide reductase
YGL031C	RPL24A____	+1.20	15674621	18797865	protein synthesis	ribosomal protein L24A
YGR142W	BTN2______	-1.10	449259	407924	unknown	unknown
YHR155W	__________	-1.04	131448	126846	unknown	unknown; similar to Sip3p
YJL031C	BET4______	+1.33	357812	476855	protein processing	geranylgeranyl transferase subunit
YKL030W	__________	-1.04	749983	719758	unknown	unknown
YLL031C	GPI13_____	-1.11	186256	168103	protein processing	phosphoryltransferase (GPI anchor synthesis)
YLR336C	SGD1______	-1.19	212598	178732	signaling (putative)	high osmolarity pathway
YMR073C	__________	-1.09	447172	411300	unknown	unknown; similar to rat cytochrome b5
YNL123W	__________	-1.23	371262	302372	unknown	unknown
YOL031C	__________	+1.19	619847	739466	unknown	unknown; similar to Yarrowia lipolytica Sls1 protein
YOR241W	MET7______	-1.13	749672	662533	methionine biosynthesis	folylpolyglutamate synthase
YPL220W	RPL1A_____	+1.19	15958128	19051328	protein synthesis	ribosomal protein L1A
YBL041W	PRE7______	+1.25	730688	912283	protein degradation	20S proteasome subunit
YDL043C	PRP11_____	-1.08	204206	189144	mRNA splicing	U2, U5, U4/U6 snRNP protein
YDR171W	HSP42_____	-1.03	336152	327680	cytoskeleton assembly	heat shock protein, similar to HSP26
YDR542W	__________	-1.02	274100	269245	unknown	unknown
YFL034W	__________	-1.16	161654	138999	unknown	unknown
YGL234W	ADE5,7____	-1.48	1690775	1142945	purine biosynthesis	phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase
YHL038C	CBP2______	-1.10	252364	229469	mRNA splicing, COB mRNA	pre-mRNA binding protein
YIL133C	RPL16A____	-1.16	11310870	9750109	protein synthesis	ribosomal protein L16A
YJR011C	__________	-1.10	281250	254649	unknown	unknown
YKR007W	__________	+1.12	514147	576700	unknown	unknown
YLR164W	__________	-1.19	171943	144648	unknown	unknown; similar to Sdh4p
YML038C	YMD8______	-1.22	468565	383537	unknown	unknown; similar to vanadate resistance protein Gog5p
YMR268C	PRP24_____	-1.21	327358	270888	mRNA splicing	U4/U6 snRNP protein
YNL325C	FIG4______	-1.09	234491	215313	mating (putative)	unknown; induced by mating factor
YOR065W	CYT1______	-1.04	1085475	1041589	oxidative phosphorylation	cytochrome c1
YPL043W	NOP4______	-1.49	569923	381922	rRNA processing	RNA binding protein
YBR113W	__________	-1.09	963369	883237	unknown	unknown
YCR051W	__________	-1.33	850344	640847	unknown	unknown; similar to ankyrin and coiled-coil protein
YDL233W	__________	-1.03	209961	204585	unknown	unknown
YDR352W	__________	-1.14	328381	286833	unknown	unknown
YER052C	HOM3______	-1.00	514715	512231	Met. and Thr. biosynthesis	aspartate kinase
YGL043W	DST1______	-1.01	109999	109424	transcription	elongation factor TFIIS
YGR154C	__________	+1.01	151495	152615	unknown	unknown
YHR167W	__________	-1.05	221284	210388	unknown	unknown
YJL044C	GYP6______	-1.02	507504	498639	secretion	GTPase-activating protein for Ypt6
YKL041W	VPS24_____	+1.12	409739	458008	vacuolar protein targeting	component of class E protein complex
YLL043W	FPS1______	-1.25	470469	376136	transport	glycerol channel protein
YLR348C	DIC1______	-1.00	205252	204764	transport	mitochondrial dicarboxylate carrier
YNL135C	FPR1______	+1.14	1157305	1321896	protein folding	peptidyl-prolyl cis-trans isomerase
YOL043C	NTG2______	-1.11	274384	247552	DNA repair	endonuclease III-like glycosylase
YOR253W	__________	+1.17	1078746	1265816	unknown	unknown
YPL232W	SSO1______	+1.18	1316424	1547940	secretion	post-Golgi t-SNARE
YBL053W	__________	-1.04	322699	309677	unknown	unknown
YDL055C	PSA1______	+1.01	3285800	3318366	mannose metabolism	mannose-1-phosphate guanyltransferase
YDR182W	CDC1______	-1.09	413051	378064	Mn2+ ion homeostasis	unknown
YFL046W	__________	+1.10	339413	374704	unknown	unknown; similar to myosin heavy chain A
YGL246C	RAI1______	-1.10	524775	475421	unknown	unknown; similar to C. elegans DOM-3 (GB:1004375)
YHL049C	__________	-1.25	258751	206690	unknown	unknown; similar to other subtelomerically-encoded proteins
YIL145C	__________	-1.18	596565	505727	unknown	unknown; similar to E. coli pantoate beta-alanine ligase
YJR023C	__________	+1.20	185706	223457	unknown	unknown; similar to sodium channel proteins
YKR019C	IRS4______	-1.05	160465	153513	silencing (rDNA)	unknown
YLR176C	RFX1______	-1.03	158384	153287	unknown	unknown; DNA binding protein
YMR280C	CAT8______	-1.01	390049	387512	gluconeogenesis	transcription factor
YNL337W	__________	+1.13	136820	154248	unknown	unknown
YOR077W	RTS2______	-1.27	171587	134715	unknown	unknown; similar to mouse KIN7 protein
YPL055C	__________	-1.03	354947	345711	unknown	unknown
YPR148C	__________	+1.22	644697	787287	unknown	unknown
YBR125C	PTC4______	+1.03	310435	319226	unknown	protein phosphatase type 2C
YCR063W	__________	-1.05	131078	124964	unknown	unknown; similar to Xenopus G10, a developmentally-regulated
YDL245C	HXT15_____	+1.08	146320	158195	transport	hexose permease
YDR364C	CDC40_____	-1.12	245830	219427	cell cycle and mRNA splicing	unknown
YER062C	HOR2______	-1.16	2190572	1884566	glycerol metabolism	DL-glycerol-3-phosphatase
YGL055W	OLE1______	-1.06	2152951	2034095	fatty acid metabolism	delta-9-fatty acid desaturase
YGR162W	TIF4631___	-1.48	526963	355551	protein synthesis	mRNA cap-binding protein (eIF4F) 150K subunit
YHR179W	OYE2______	+1.27	3267831	4137299	unknown	NAPDH dehydrogenase (old yellow enzyme)
YJL056C	ZAP1______	-1.09	157296	144199	transport (Zn)	transcription factor
YKL053W	__________	+1.24	407603	504511	unknown	unknown
YLL055W	__________	+1.03	113972	117172	unknown	unknown; similar to Dal5p and members of the allantoate
YLR360W	VPS38_____	+1.16	369459	427445	vacuolar protein targeting	unknown
YMR095C	SNO1______	-1.12	141020	125506	unknown	unknown; induced in stationary phase
YNL147W	LSM7______	+1.12	666895	749458	mRNA splicing (putative)	similar to snRNA-associated protein
YOL053W	__________	-1.03	232197	225949	unknown	unknown
YOR265W	RBL2______	+1.04	566660	588266	cytoskeleton	beta-tubulin binding protein
YPL244C	HUT1______	-1.02	300454	294945	unknown	unknown
YBL065W	__________	+1.06	90774	96398	unknown	unknown
YDL067C	COX9______	+1.48	636365	939611	oxidative phosphorylation	cytochrome c oxidase assembly
YDR194C	MSS116____	-1.34	418766	313371	mRNA splicing, mitochondrial	RNA helicase
YFL058W	THI5______	+1.15	141541	162959	pyrimidine biosynthesis	unknown
YGL258W	__________	+1.02	150068	152535	unknown	unknown
YHR009C	__________	+1.12	327326	365106	unknown	unknown
YJR034W	PET191____	+1.18	268088	316754	respiration	cytochrome c oxidase assembly
YKR031C	SPO14_____	+1.01	113083	114003	meiosis	phospholipase D

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YLR188W	MDL1______	-1.10	199171	181600	transport	ATP-binding cassette (ABC) family
YML058W	SML1______	+1.34	1439577	1922795	DNA replication (putative)	regulator of ribonucleotide reductase (putative)
YMR291W	__________	+1.13	203269	229359	unknown	unknown
YNR010W	CSE2______	+1.34	202426	271674	mitosis, chromosome segregation	kinetochore protein (putative)
YOR089C	VPS21_____	+1.10	846399	929453	endocytosis	rab5-like GTPase
YPL065W	VPS28_____	+1.14	277677	317114	vacuolar protein targeting	cytoplasmic protein
YBR137W	__________	+1.09	97990	106721	unknown	unknown
YCR073W	SOL2______	-1.01	90004	88752	tRNA splicing, putative	unknown
YDR009W	GAL3______	+1.04	109996	113966	galactose metabolism	galactokinase
YDR374C	__________	-1.00	102416	102390	unknown	unknown
YER071C	__________	+1.03	181895	187566	unknown	unknown
YGL067W	NPY1______	+1.10	97087	107237	NAD metabolism	NAD+ pyrophosphatase
YGR174C	CBP4______	+1.14	418990	476135	respiration	ubiquinol--cytochrome-c reductase assembly factor
YHR191C	CTF8______	+1.01	502737	508614	mitosis (putative)	kinetochore protein (putative)
YJL068C	__________	+1.17	329481	384044	unknown	unknown; similar to human esterase D
YKL065C	YET1______	+1.87	758128	1416960	unknown	ER 25 kDa transmembrane protein
YLL067C	__________	+1.01	119288	120959	unknown	unknown; similar to other subtelomerically-encoded proteins
YLR372W	SUR4______	-1.14	1228994	1082796	fatty acid metabolism	conversion of 24-carbon to 26-carbon fatty acids
YMR107W	__________	+1.01	132117	133545	unknown	unknown
YNL159C	__________	-1.01	281021	276998	unknown	unknown
YOL065C	INP54_____	-1.06	287570	271075	unknown	putative inositol polyphosphate 5-phosphatase
YOR277C	__________	-1.03	2258923	2196266	unknown	unknown
YPL255W	BBP1______	-1.19	297642	249532	cell cycle and meiosis	unknown
YMR322C	__________	-1.09	130731	120058	unknown	unknown
YBL077W	__________	+1.09	2253815	2456315	unknown	unknown
YDL079C	MRK1______	-1.05	213687	204436	unknown	protein kinase
YDR206W	EBS1______	-1.09	185593	170163	unknown	unknown; similar to Est1p; bcy1 suppressor
YFR002W	NIC96_____	-1.13	306481	270392	nuclear protein targeting	nuclear pore protein
YGR007W	MUQ1______	-1.14	453500	397557	phospholipid metabolism	choline phosphate cytidylyltransferase
YHR021C	RPS27B____	-1.03	6484790	6271044	protein synthesis	ribosomal protein S27B
YIL168W	SDL1______	-1.40	242074	172315	gluconeogenesis	serine dehydratase
YJR046W	TAH11_____	-1.36	408004	299122	unknown	unknown
YKR043C	__________	-1.13	786212	694130	unknown	unknown
YLR200W	YKE2______	+1.18	590290	695633	cytoskeleton	microtubule nucleation
YML070W	DAK1______	+1.03	464555	480281	carbohydrate metabolism; stress response	dihydroxyacetone kinase
YMR302C	PRP12_____	-1.05	244728	233222	rRNA processing	mitochondrial inner membrane protein
YNR022C	__________	+1.08	489141	530578	unknown	unknown
YOR101W	RAS1______	-1.57	718587	457866	signaling, Ras pathway	GTP-binding protein, ras homolog
YPL077C	__________	-1.05	194613	184958	unknown	unknown; similar to Ybr197p
YPR168W	NUT2______	-1.11	117569	105598	mating type switching	negative regulator of HO expression
YBR149W	ARA1______	+1.33	616000	818292	arabinose metabolism	arabinose dehydrogenase
YCR087W	__________	-1.21	2890502	2381944	unknown	unknown
YDR021W	FAL1______	-1.16	460595	397646	rRNA processing	RNA helicase
YDR386W	MUS81_____	-1.09	165364	151841	DNA repair (putative)	unknown
YER083C	__________	-1.09	731763	673451	unknown	unknown
YGL079W	__________	+1.04	306209	318895	unknown	unknown
YGR186W	TFG1______	-1.26	774185	612853	transcription	TFIIF 105 kD subunit
YHR203C	RPS4B_____	+1.19	15826584	18896579	protein synthesis	ribosomal protein S4B
YJL080C	SCP160____	-1.32	1218193	919675	mitosis, chromosome transmission	unknown
YKL077W	__________	-1.17	712088	611129	unknown	unknown
YLR012C	__________	-1.20	268596	224415	unknown	unknown
YLR384C	IKI3______	-1.27	1314668	1038265	killer toxin sensitivity	unknown
YMR119W	__________	-1.26	228114	181160	unknown	unknown
YNL171C	__________	+1.04	177171	184485	unknown	unknown
YOL077C	__________	-1.22	2155469	1760234	unknown	unknown; similar to C. elegans Kq2H4.3 protein
YOR289W	__________	+1.38	198792	274055	unknown	unknown
YPL265W	DIP5______	-1.20	428641	356805	transport	dicarboxylic amino acid permease
YBL089W	__________	-1.18	103919	88251	unknown	major facilitator superfamily
YDL091C	__________	+1.01	201649	203044	unknown	unknown
YDR214W	__________	-1.08	652824	605341	unknown	unknown
YFR014C	CMK1______	-1.14	229687	201192	signaling	calmodulin-dependent protein kinase
YGR019W	UGA1______	+1.16	228415	265349	GABA metabolism	4-aminobutyrate aminotransferase (GABA transaminase)
YHR032W	__________	-1.59	290579	183226	unknown	major facilitator superfamily
YIR002C	MPH1______	-1.14	270519	236794	unknown; mutator null phenotype	unknown; similar to ATP-dependent RNA helicases
YJR058C	APS2______	+1.22	486740	591976	secretion	AP-1 complex subunit
YKR055W	RHO4______	-1.16	222246	191597	signaling	GTP-binding protein, rho family
YLR212C	TUB4______	-1.04	335268	322811	cytoskeleton	gamma-tubulin
YML082W	__________	-1.39	263585	189497	unknown	unknown; similar to O-succinylhomoserine (thiol)-lyase
YMR312W	__________	-1.25	370614	296347	unknown	unknown
YNR034W	SOL1______	-1.35	289871	215382	tRNA splicing, putative	unknown
YOR113W	AZF1______	-1.11	144493	130353	transcription (putative)	similar to Zn-finger transcription factors
YPL089C	RLM1______	+1.05	972294	1016485	cell wall organization	MADS box transcription factor
YPR180W	AOS1______	-1.15	394046	342461	protein degradation, Smt3p-mediated	Smt3p activating protein
YBR161W	__________	+1.01	226681	228094	unknown	unknown; similar to Sur1p, Hoc1p, and Och1p
YCR097W	HMRA1_____	-1.09	121334	111248
YDR033W	MRH1______	+1.19	2236757	2665511	unknown	similar to Yro2p and Hsp30p
YDR398W	__________	-1.35	235346	173865	unknown	unknown
YGL091C	NBP35_____	+1.07	369248	395620	unknown	unknown; essential; similar to bacterial partitioning ATPases
YGR198W	__________	-1.12	706431	629187	unknown	unknown
YJL092W	HPR5______	-1.08	195414	180478	meiosis	DNA helicase
YKL089W	MIF2______	-1.07	220720	207125	mitosis	centromere protein
YLR024C	UBR2______	-1.12	535614	478243	protein degradation, ubiquitin-mediated	ubiquitin-protein ligase
YLR396C	VPS33_____	-1.11	659356	593063	vacuolar protein targeting	Sec1 protein family
YMR130W	__________	+1.07	525591	560500	unknown	unknown
YNL183C	NPR1______	-1.21	190249	156900	transport	protein kinase; regulates activity of nitrogen source transporters
YOL089C	HAL9______	-1.09	228719	208958	salt tolerance	transcription factor (putative)
YOR300W	__________	+1.24	235280	292302	unknown	unknown
YPL277C	__________	+1.04	198177	206844	unknown	unknown
YAL009W	SPO7______	+1.01	87987	89211	meiosis	unknown
YBR173C	UMP1______	+1.06	343402	363191	protein degradation, ubiquitin-mediated	20S proteasome maturation factor
YCRX03C	__________	+1.01	94886	95648
YDR044W	HEM13_____	-1.30	270732	208692	heme biosynthesis	coproporphyrinogen III oxidase
YDR411C	__________	+1.07	317735	340586	unknown	unknown
YER106W	__________	+1.03	104709	108366	unknown	unknown
YGL104C	__________	-1.03	139269	135677	unknown	unknown; similar to glucose transport proteins
YGR211W	ZPR1______	-1.30	604777	466005	unknown	unknown; zinc finger protein
YIL008W	URM1______	-1.03	505119	490823	protein modification	ubiquitin-like protein
YJL105W	__________	-1.03	150033	146249	unknown	unknown; similar to Ykr029p
YKL101W	HSL1______	+1.34	370499	497736	cell cycle	negative regulator of swe1 kinase
YLR409C	__________	-1.26	179659	142556	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL196C	SLZ1______	-1.52	233963	153888	meiosis	unknown
YOL102C	TPT1______	+1.04	387580	404377	tRNA splicing	2'-phosphotransferase
YOR312C	RPL20B____	+1.07	14784365	15779242	protein synthesis	ribosomal protein L20B
YPR007C	SPO69_____	-1.10	193799	175557	sporulation	unknown
YBL101W	TY2A______	-1.04	1222267	1171620	unknown	unknown
YCL007C	CWH36_____	+1.06	665469	702261	cell wall biogenesis	unknown
YDL104C	QRI7______	+1.22	146099	178886	unknown	unknown; similar to E. coli orfx gene
YDR227W	SIR4______	+1.01	114710	115790	silencing	nuclear coiled-coil protein, regulator of silencing
YEL008W	__________	+1.03	121628	124752	unknown	unknown
YFR027W	ECO1______	+1.03	142082	146359	mitosis, sister chromatid cohesion (putative)	unknown
YGR030C	POP6______	+1.03	250421	257018	tRNA processing	RNase P and RNase MRP subunit
YHR044C	DOG1______	+1.15	353751	406840	2-deoxyglucose resistance	2-deoxyglucose-6-phosphate phosphatase
YIR015W	RPR2______	-1.14	133273	116527	tRNA processing	RNase P subunit
YJR071W	__________	-1.58	287150	181553	unknown	unknown
YKR068C	BET3______	+1.20	561477	675473	secretion	SNARE docking complex assembly
YLR225C	__________	+1.23	328667	403869	unknown	unknown
YNL008C	__________	-1.01	686708	681844	unknown	unknown; similar to Mdj2p, E. coli DnaJ, and other DnaJ-like
YNR047W	__________	-1.33	1001894	752871	unknown	unknown
YOR126C	IAH1______	+1.20	356888	427919	unknown	isoamyl acetate hydrolytic enzyme
YPL102C	__________	-1.30	140313	107692	unknown	unknown
YPR193C	HPA2______	-1.06	131010	123217	chromatin structure	histone acetyltransferase complex subunit
YAL021C	CCR4______	+1.03	90270	93101	catabolite repression	component of CCR4 transcriptional complex
YBR185C	MBA1______	-1.02	208448	204455	respiration	mitochondrial respiratory complex assembly
YCRX15W	__________	-1.02	110083	107744
YDR056C	__________	+1.03	632209	652439	unknown	unknown
YDR423C	CAD1______	-1.03	250606	244045	transcription	basic leu zipper transcription factor
YER118C	SHO1______	+1.01	416568	421490	signaling, high osmolarity pathway	transmembrane osmosensor
YGL116W	CDC20_____	-1.09	256344	235484	mitosis	activator of the anaphase promoting complex
YGR223C	__________	+1.05	246600	257843	unknown	unknown
YIL019W	__________	-1.45	525018	362987	unknown	unknown
YJL117W	PHO86_____	+1.13	862202	975729	transport	inorganic phosphate permease
YKL113C	RAD27_____	+1.03	357130	366579	DNA repair	ssDNA endonuclease
YLR047C	__________	-1.10	117023	106041	unknown	unknown
YLR419W	__________	-1.23	399566	323832	unknown	unknown; similar to pre-mRNA splicing factors
YNL208W	__________	+1.62	1045700	1692317	unknown	unknown
YOL112W	MSB4______	+1.13	371135	421065	unknown	unknown; suppresses bud emergence defect
YOR324C	__________	-1.01	134755	133421	unknown	unknown
YPR019W	CDC54_____	-1.17	288108	246295	DNA replication	MCM initiator complex
YBL112C	__________	-1.35	160285	118895	unknown	unknown
YCL020W	__________	-1.13	1370872	1210377	unknown	unknown
YDL116W	NUP84_____	-1.17	268906	229611	nuclear protein targeting	nuclear pore protein
YEL019C	MMS21_____	+1.01	114214	115817	DNA repair	unknown
YHR055C	CUP1-2____	-1.21	4355957	3612824	Cu2+ ion homeostasis	metallothionein
YIR024C	GIF1______	+1.03	271022	280229	cell cycle, G1	unknown
YJR084W	__________	-1.15	281051	244226	unknown	unknown; similar to human sodium channel protein HI
YKR080W	MTD1______	-1.07	900098	837818	nucleotide metabolism	NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase
YLR235C	__________	-1.14	117806	103759	unknown	unknown
YML104C	MDM1______	-1.14	143358	125231	cytoskeletal organization	intermediate filament protein
YNL020C	ARK1______	+1.03	368475	377798	unknown	protein kinase
YNR059W	MNT4______	-1.06	154938	146114	protein glycosylation	mannosyltransferase
YOR138C	__________	-1.08	228316	212289	unknown	unknown
YPL114W	__________	-1.16	174151	149834	unknown	unknown
YAL032C	PRP45_____	-1.18	175109	148515	mRNA splicing	U2, U5, U6 snRNP protein
YBR197C	__________	-1.13	168480	148826	unknown	unknown
YDR068W	DOS2______	-1.03	326045	316226	unknown	unknown
YDR435C	PPM1______	+1.01	210578	212621	protein modification	carboxymethyltransferase
YER129W	PAK1______	-1.01	134932	133094	DNA replication	protein kinase; suppresses pol. alpha mutations
YGL128C	__________	-1.16	544295	471062	unknown	unknown; similar to E. coli DnaJ and other DnaJ-like
YGR235C	__________	+1.09	645064	700007	unknown	unknown
YIL031W	ULP2______	-1.06	143511	135919	unknown	unknown; suppresses mif2 mutation
YJL129C	TRK1______	-1.09	420784	385962	transport	potassium permease
YKL125W	RRN3______	-1.00	306018	304985	transcription	RNA polymerase I transcription factor
YLR059C	REX2______	-1.17	364081	311446	RNA processing	RNA exonuclease
YLR429W	CRN1______	-1.11	522488	472500	cytoskeleton	coronin
YMR164C	MSS11_____	+1.02	2153140	2199797	starch metabolism	(putative) transcriptional repressor
YNL220W	ADE12_____	-1.34	2904068	2166859	purine biosynthesis	adenylosuccinate synthetase
YOL124C	__________	-1.36	854071	630032	unknown	unknown
YOR336W	KRE5______	-1.02	520157	507499	cell wall biogenesis	unknown; ER resident glycoprotein
YPR031W	__________	-1.23	491503	400510	unknown	unknown; similar to human zinc finger protein PIR:JC2069
YBR011C	IPP1______	-1.30	4087425	3150007	phosphate metabolism	inorganic pyrophosphatase, cytoplasmic
YCL032W	STE50_____	-1.13	236447	210059	signaling	pheromone response
YDL128W	VCX1______	-1.03	489288	475274	transport	vacuolar H+/Ca(2+) exchanger
YDR251W	PAM1______	+1.03	215994	222247	unknown	unknown; overexpression suppresses PP2A depletion
YEL031W	SPF1______	-1.06	110534	103869	transport	(putative) Ca(2+) ATPase
YFR048W	__________	+1.02	196959	201674	unknown	unknown
YGR049W	SCM4______	+1.03	491356	507985	cell cycle	suppresses cdc4 mutation
YHR065C	RRP3______	-1.11	589815	531668	rRNA processing	RNA helicase
YIR036C	__________	+1.05	244821	257111	unknown	unknown; similar to proteins of the short-chain alcohol
YJR095W	SFC1______	-1.11	128020	114825	transport	mitochondrial succinate-fumarate carrier
YKR092C	SRP40_____	-1.06	893709	840729	transcription (putative)	Suppressor of mutant AC40 subunit of RNA polymerase I and III
YLR247C	__________	+1.07	346618	371992	unknown	unknown; similar to Rad16p
YML116W	ATR1______	-1.47	373234	254648	aminotriazole resistance	transporter (putative)
YNL032W	SIW14_____	+1.01	455559	459036	cell cycle	tyrosine phosphatase
YNR071C	__________	-1.06	144873	136652	unknown	unknown; similar to UDPglucose 4-epimerase
YOR148C	SPP2______	+1.09	319417	349481	mRNA splicing	spliceosome-associated protein
YPL126W	NAN1______	-1.31	1091709	832454	unknown	unknown; nucleolar protein
YAL042W	ERV46_____	+1.07	674739	721263	unknown	unknown; ER vesicle protein
YBR209W	__________	-1.14	120895	106017	unknown	unknown
YDR080W	VPS41_____	-1.02	282351	276327	vacuolar protein targeting	component of vacuolar membrane protein complex
YDR447C	RPS17B____	-1.09	10575736	9660232	protein synthesis	ribosomal protein S17B
YER139C	__________	-1.10	213401	194114	unknown	unknown
YGL140C	__________	-1.52	420479	276875	unknown	major facilitator superfamily
YGR247W	__________	+1.03	190921	197330	unknown	unknown
YIL043C	CBR1______	+1.09	1677133	1830800	aminosugars metabolism	cytochrome b reductase
YJL141C	YAK1______	-1.03	303079	294728	signaling	serine-threonine protein kinase
YKL137W	__________	+1.14	273279	312581	unknown	unknown
YLR071C	RGR1______	-1.14	143447	125731	transcription	RNA polymerase II mediator subunit
YLR441C	RPS1A_____	+1.20	15713716	18881783	protein synthesis	ribosomal protein S1A
YNL232W	CSL4______	-1.24	567892	456268	mitosis, chromosome segregation	unknown
YOL136C	PFK27_____	-1.24	454784	367779	fructose metabolism	6-phosphofructo-2-kinase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOR346W	REV1______	-1.28	249986	194994	DNA repair	deoxycytidyl transferase
YPR043W	RPL43A____	+1.06	15599936	16496579	protein synthesis	ribosomal protein L34A
YBR021W	FUR4______	+1.02	89979	92137	transport	uracil permease
YCL044C	__________	+1.11	186985	207765	unknown	unknown
YDL138W	RGT2______	-1.06	210401	199406	transport	glucose permease
YEL043W	__________	-1.09	211028	193463	unknown	unknown
YGR061C	ADE6______	-1.17	154198	131263	purine biosynthesis	5'-phosphoribosylformyl glycinamidine synthetase
YHR076W	__________	-1.02	475522	465019	unknown	unknown
YJR107W	__________	+1.23	299231	367630	unknown	unknown; similar to acylglycerol lipase
YKR104W	__________	-1.00	123161	123116	unknown	ATP-binding cassette (ABC) superfamily
YML127W	__________	-1.22	402411	329010	unknown	unknown
YNL042W	BOP3______	-1.10	288324	261417	unknown	unknown; bypass of PAM1
YOR160W	MTR10_____	-1.38	544491	393272	mRNA export	Npl3p import factor
YPL138C	__________	-1.05	316559	301145	unknown	unknown
YAL055W	PEX22_____	+1.32	202457	268174	peroxisome biogenesis (putative)	peroxisomal membrane anchoring protein (puttaive)
YBR221C	PDB1______	-1.18	1156161	979841	glycolysis	pyruvate dehydrogenase
YDR092W	UBC13_____	+1.17	377399	443060	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YDR459C	__________	-1.09	204161	186574	unknown	unknown; similar to protein PIR:S51289
YER149C	PEA2______	-1.01	190893	189267	mating	unknown
YGL152C	__________	+1.06	169931	180737	unknown	unknown; similar to rat G protein-coupled glutamate
YGR259C	__________	-1.18	125620	106626	unknown	unknown
YIL055C	__________	+1.04	213986	222709	unknown	unknown
YJL153C	INO1______	+1.00	117507	117693	inositol biosynthesis	L-myo-inositol-1-phosphate synthase
YKL149C	DBR1______	-1.03	257995	250837	mRNA splicing	debranching enzyme
YLR083C	EMP70_____	-1.12	144848	129575	secretion (putative)	endosomal membrane protein
YLR453C	RIF2______	+1.07	160496	172061	silencing	RAP1-interacting protein
YMR186W	HSC82_____	-1.63	4866872	2986888	protein folding	chaperonin
YNL244C	SUI1______	+1.06	3757827	3987584	protein synthesis	translation initiation factor 3 (eIF3)
YOL148C	SPT20_____	-1.11	384297	346383	chromatin structure	histone acetyltransferase complex subunit
YOR358W	HAP5______	-1.13	295094	260078	respiration	transcription factor
YPR055W	SEC8______	+1.00	159250	159959	secretion	exocyst complex subunit
YBR033W	__________	+1.07	88246	94775	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6] cluster domain
YCL056C	__________	+1.27	288595	367810	unknown	unknown
YDL150W	RPC53_____	-1.31	703041	535736	transcription	RNA polymerase III 47 kD subunit
YDR271C	__________	+1.23	175243	215597	unknown	unknown
YEL055C	POL5______	-1.06	194782	183584	DNA replication	DNA polymerase V
YGR073C	__________	-1.15	183762	160080	unknown	unknown
YHR087W	__________	+1.29	154126	199299	unknown	unknown
YJR119C	__________	-1.05	157057	150237	unknown	unknown; similar to human retinoblastoma binding protein 2
YLR267W	BOP2______	-1.08	150254	139368	unknown	unknown; bypass of PAM1
YNL054W	VAC7______	+1.08	610321	659834	vacuole biogenesis	unknown; vacuolar integral membrane protein
YOR172W	__________	-1.06	128580	121485	unknown	unknown; similar to transcription factors
YPL150W	__________	+1.04	117850	122385	unknown	unknown
YAL066W	__________	-1.01	108754	107823	unknown	unknown
YBR233W	PBP2______	-1.09	207059	190003	unknown	interacts with Pab1p
YDR102C	__________	+1.03	104358	107324	unknown	unknown
YDR471W	RPL27B____	-1.00	13077445	13075169	protein synthesis	ribosomal protein L27B
YGL164C	__________	-1.06	138396	130570	unknown	unknown
YGR271W	__________	-1.01	340247	337094	unknown	unknown; similar to Ski2p
YJL165C	HAL5______	-1.11	357920	321099	salt tolerance	putative protein kinase
YKL161C	__________	+2.32	165271	383964	unknown	putative protein kinase
YLR095C	IOC2______	-1.03	273874	266201	unknown	unknown
YLR465C	__________	-1.16	136434	117377	unknown	unknown
YMR197C	VTI1______	+1.27	370297	471845	secretion	cis-Golgi v-SNARE
YNL256W	FOL1______	-1.26	631770	503096	folate biosynthesis	dihydroneopterin aldolase, dihydro-6-hydroxymethylpterin pyrophosphokinase, dihydropteroate synthetase
YOL160W	__________	-1.01	128731	127881	unknown	unknown
YOR370C	MRS6______	-1.12	761176	681142	protein processing	Rab geranylgeranyltransferase regulatory subunit
YPR067W	ISA2______	+1.19	285259	338378	unknown	unknown; Iron Sulfur Assembly -- IscA/NifA homolog
YBR045C	GIP1______	+1.01	88298	88810	glucose repression	(putative) Glc7p regulatory subunit
YCL068C	__________	+1.01	100173	101185	unknown	unknown
YDL162C	__________	-1.02	100510	98609	unknown	unknown
YDR283C	GCN2______	-1.18	313986	266373	protein synthesis	eIF2alpha kinase
YEL066W	HPA3______	+1.27	260647	330059	chromatin structure	histone acetyltransferase complex subunit
YGR085C	RPL11B____	+1.19	15711867	18696820	protein synthesis	ribosomal protein L11B
YHR099W	TRA1______	-1.06	548972	518600	unknown	unknown; similar to human TR-AP
YJR131W	MNS1______	-1.26	279227	222130	protein glycosylation	specific alpha-mannosidase
YLR279W	__________	-1.08	202821	187984	unknown	unknown
YMR018W	__________	+1.00	159830	160438	unknown	unknown; similar to Pex5p/Pas10p (GB:Z49211)
YNL064C	YDJ1______	-1.34	3688568	2750572	mitochondrial and ER protein targeting	HSP70 associated chaperone
YOR184W	SER1______	-1.46	2119673	1447390	serine biosynthesis	phosphoserine
YPL162C	__________	-1.17	210175	179017	unknown	unknown
YAR018C	KIN3______	-1.21	305470	253360	unknown	protein kinase
YBR245C	ISW1______	-1.20	149054	124164	unknown	unknown; similar to Drosophila nucleosome remodeling
YDR114C	__________	+1.00	149614	149653	unknown	unknown
YDR483W	KRE2______	+1.19	1383593	1650391	protein glycosylation	alpha-1,2-mannosyltransferase
YER170W	ADK2______	+1.00	205393	205706	purine metabolism	adenylate kinase,
YGL176C	__________	+1.06	165124	174385	unknown	unknown; similar to Discopyge ommata Ca++ channel alpha1
YGR283C	__________	+1.19	709532	842782	unknown	unknown
YIL076W	SEC28_____	+1.23	1186193	1458400	secretion	vesicle coat component
YJL177W	RPL17B____	+1.19	15868556	18881419	protein synthesis	ribosomal protein L17B
YKL173W	SNU114____	-1.19	505245	425645	mRNA splicing	U5 snRNP protein
YLR107W	REX3______	+1.27	274879	349129	RNA processing	RNA exonuclease
YMR209C	__________	-1.16	351650	302639	unknown	unknown
YNL268W	LYP1______	-1.34	312241	232783	transport	lysine permease
YOR006C	__________	-1.07	758265	705430	unknown	unknown
YOR382W	__________	-1.30	338521	261128	unknown	unknown
YPR079W	__________	+1.01	291903	295400	unknown	unknown
YBR057C	MUM2______	-1.25	382960	306423	meiosis	unknown; similar to ubiquitin C-terminal hydrolase
YCLX07W	__________	-1.31	137379	104599
YDL174C	DLD1______	+1.17	638543	747589	pyruvate metabolism	D-lactate dehydrogenase
YDR295C	PLO2______	-1.03	118469	114906	unknown; ploidy-related	unknown
YEL077C	__________	-1.14	814763	711669	unknown	unknown
YGR097W	ASK10_____	-1.05	196894	188046	stress response	enhancer of SKN7-dependent transcription
YHR111W	__________	+1.00	752545	756069	unknown	unknown; similar to Uba1p and molybdopterin biosynthesis
YJR143C	PMT4______	-1.22	776167	638445	protein glycosylation	dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
YLR290C	__________	+1.15	259537	299671	unknown	unknown
YMR030W	__________	-1.02	177646	173728	unknown	unknown
YNL076W	MKS1______	-1.13	288061	253960	signaling, Ras pathway	negative regulator of cAMP-dependent genes
YOR194C	TOA1______	-1.15	629503	546398	transcription	TFIIA 32 kD subunit
YPL174C	NIP100____	-1.19	132241	111008	nuclear protein targeting	(putative) large subunit of dynactin complex

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YAR040C	__________	-1.20	116508	97204
YBR257W	POP4______	+1.07	279018	297831	rRNA and tRNA processing	RNase P and RNase MRP subunit
YDR126W	__________	-1.04	164850	157791	unknown	unknown
YDR495C	VPS3______	-1.06	322393	304706	vacuolar protein targeting	unknown
YER181C	__________	-1.02	313103	308268	unknown	unknown
YGL188C	__________	+1.17	380372	443965	unknown	unknown
YGR295C	COS6______	+1.61	1853933	2987083	unknown	unknown; similar to other subtelomerically-encoded proteins
YIL087C	__________	+1.12	294132	328160	unknown	unknown
YJL189W	RPL39_____	+1.18	6787170	8033664	protein synthesis	ribosomal protein L39
YKL185W	ASH1______	+1.05	720258	755903	mating type switching	transcription factor
YLR119W	SRN2______	+1.03	116668	119659	RNA export, putative	unknown
YMR221C	__________	-1.14	548117	481496	unknown	major facilitator superfamily
YNL280C	ERG24_____	-1.25	163817	130845	sterol metabolism	C-14 sterol reductase
YOR018W	ROD1______	+1.09	337271	365984	drug resistance	unknown
YOR394W	__________	+1.04	264142	275736	unknown	unknown; similar to PAU1 family
YPR091C	__________	-1.03	137033	133411	unknown	unknown
YBR069C	TAT1______	-1.24	360819	291724	transport	amino acid permease
YCR007C	__________	+1.03	167527	173227	unknown	unknown; similar to subtelomerically-encoded proteins
YDL186W	__________	-1.08	166406	153647	unknown	unknown
YDR307W	__________	-1.06	221399	209507	unknown	unknown; similar to Pmt1p
YER010C	__________	-1.04	303418	292599	unknown	unknown
YGR109C	CLB6______	-1.07	177582	165604	cell cycle	B-type cyclin; S phase
YHR123W	EPT1______	-1.04	2028688	1945311	phospholipid metabolism	sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase
YJR155W	AAD10_____	-1.17	417609	357134	unknown	hypothetical aryl-alcohol dehydrogenase
YLR302C	__________	-1.19	125707	106032	unknown	unknown
YMR041C	__________	+1.07	220369	236751	unknown	unknown
YNL088W	TOP2______	-1.06	1029133	974472	DNA replication	DNA topoisomerase II
YOR206W	__________	-1.40	706011	504523	unknown	unknown
YPL185W	__________	-1.05	140595	133601	unknown	unknown
YBL006C	__________	-1.48	377399	255478	unknown	unknown
YBR269C	__________	+1.00	208394	209366	unknown	unknown
YDL008W	APC11_____	+1.10	113211	124983	mitosis	anaphase promoting complex subunit
YDR138W	HPR1______	+1.04	99971	103602	mitosis, recombination	related to topoisomerase
YDR507C	GIN4______	-1.23	460126	374865	cell cycle (growth inhibitor)	protein kinase
YFL006W	__________	-1.17	511470	437930	unknown	unknown
YGL200C	EMP24_____	-1.00	1951985	1947521	secretion	vesicle coat component
YIL099W	SGA1______	-1.02	126570	123662	sporulation	glucan 1,4-alpha-glucosidase
YJL201W	ECM25_____	-1.13	240539	212072	cell wall biogenesis	unknown
YKL197C	PEX1______	-1.21	161844	133730	peroxisome biogenesis	ATPase (putative)
YLR131C	ACE2______	+1.04	87243	90805	transcription	CUP1 regulator
YML008C	ERG6______	-1.05	4653459	4423235	sterol metabolism	S-adenosyl-methionine delta-24-sterol-c-methyltransferase
YMR233W	__________	-1.11	275058	247410	unknown	unknown; similar to Bud7p
YNL290W	RFC3______	-1.13	617839	548160	DNA replication	replication factor C 40 kD subunit
YOR030W	DFG16_____	-1.10	129414	117202	invasive growth	unknown
YPL008W	CHL1______	-1.19	171545	143813	mitosis	kinetochore protein, DEAH box family
YPR103W	PRE2______	+1.00	1319626	1325174	protein degradation	20S proteasome subunit (beta5)
YBR081C	SPT7______	+1.01	134517	136318	chromatin structure	histone acetyltransferase complex subunit
YCR019W	MAK32_____	-1.20	188658	157161	dsRNA virus propagation	unknown
YDL198C	YHM1______	-1.11	452188	407973	transport	mitochondrial carrier family
YDR317W	__________	-1.13	187340	166236	unknown	unknown
YER020W	GPA2______	-1.20	227251	190151	signaling	G protein alpha subunit
YGL008C	PMA1______	-1.41	4522491	3215106	H+ homeostasis	plasma membrane H+-ATPase
YGR119C	NUP57_____	-1.07	514209	478898	nuclear protein targeting	nuclear pore protein
YHR134W	__________	+1.08	259031	279524	unknown	unknown
YJL008C	CCT8______	-1.29	1211403	938754	protein folding	cytoplasmic chaperonin complex
YKL007W	CAP1______	+1.24	685260	848711	cytoskeleton	actin capping protein subunit
YLL008W	DRS1______	-1.45	838793	578367	rRNA processing	RNA helicase
YLR313C	SPH1______	+1.01	106818	108013	bud site selection, bipolar	unknown; interacts with MAPKKs
YMR051C	__________	-1.29	3693100	2856669	unknown	unknown
YNL100W	__________	+1.09	506625	552149	unknown	unknown
YOL008W	__________	+1.05	285723	300474	unknown	unknown
YOR218C	__________	-1.26	536408	427311	unknown	unknown
YPL197C	__________	-1.12	991018	882434	unknown	unknown
YBL018C	POP8______	-1.07	300666	281717	tRNA processing	RNase P and RNase MRP subunit
YBR281C	__________	-1.06	134790	127257	unknown	unknown
YDL020C	RPN4______	-1.05	376328	358360	protein degradation, ubiquitin-mediated	26S proteasome subunit
YDR150W	NUM1______	+1.08	91674	99184	mitosis, nuclear migration	unknown
YDR519W	FKB2______	+1.27	422675	537979	protein folding	peptidyl-prolyl cis-trans isomerase
YFL015C	__________	+1.18	132992	156271	unknown	unknown
YGL212W	VAM7______	-1.08	154902	142916	vacuole biogenesis	unknown; regulator
YHL016C	DUR3______	+1.01	134199	134926	transport	urea permease
YIL110W	__________	-1.24	560291	451801	unknown	unknown
YJL213W	__________	-1.31	216083	165574	unknown	unknown; similar to Nocardia aryldialkylphosphatase
YKL209C	STE6______	+1.02	98949	100439	mating	a-factor exporter (ABC superfamily)
YLR143W	__________	-1.20	193009	161342	unknown	unknown; similar to Mmd1p
YNL302C	RPS19B____	+1.08	15578227	16858468	protein synthesis	ribosomal protein S19B
YOR042W	__________	-1.05	608865	577167	unknown	unknown
YPL020C	ULP1______	+1.20	255093	306709	protein degradation	Ubl (ubiquitin-like protein) - specific protease
YPR115W	__________	+1.01	174759	176681	unknown	unknown
YBR091C	MRS5______	+1.04	99336	103557	mitochondrial protein targeting	inner membrane carrier protein
YCR029C	RIM1______	+1.03	119177	123348
YDL210W	UGA4______	+1.08	117535	127191	transport	GABA-specific permease
YDR329C	PEX3______	-1.26	204598	162012	peroxisomal protein targeting	integral membrane protein
YER032W	FIR1______	-1.19	184902	154974	mRNA 3'-end processing	unknown
YGL020C	__________	-1.12	436187	388650	unknown	unknown
YGR131W	__________	-1.07	149236	139649	unknown	unknown
YHR144C	DCD1______	-1.03	344941	335566	pyrimidine metabolism	deoxycytidylate deaminase
YJL020C	__________	-1.04	295345	283970	unknown	unknown
YKL019W	RAM2______	-1.07	436330	408868	protein processing	protein farnesyltransferase, alpha subunit
YLL020C	__________	-1.03	175636	170564	unknown	unknown
YLR325C	RPL38_____	-1.07	10339518	9660624	protein synthesis	ribosomal protein L38
YNL112W	DBP2______	-1.35	6712890	4976619	mRNA decay	RNA helicase
YOL020W	TAT2______	-1.18	835423	708571	transport	tryptophan permease
YOR230W	WTM1______	-1.01	909775	903657	meiosis	transcription factor
YPL209C	IPL1______	-1.06	214573	202106	mitosis, chromosome segregation	protein kinase
YBL030C	PET9______	+1.05	1607531	1686071	transport	mitochondrial ADP/ATP translocator
YBR293W	__________	-1.13	172589	152636	unknown	major facilitator superfamily
YDL032W	__________	-1.06	115379	108907	unknown	unknown
YDR162C	NBP2______	+1.02	226362	230366	unknown	interacts with Nap1p
YDR531W	__________	-1.05	428562	407184	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YFL025C	BST1______	-1.06	165166	156438	secretion	negative regulator of COPII vesicle formation
YGL224C	__________	+1.17	350202	411194	unknown	unknown
YHL028W	WSC4______	-1.21	280138	231112	cell wall integrity and stress response	unknown
YIL122W	__________	+1.02	176054	180266	unknown	unknown
YJR001W	__________	+1.08	500440	542375	unknown	major facilitator superfamily
YKL221W	__________	-1.07	125382	117149	unknown	unknown; similar to mammalian monocarboxylate
YLR155C	ASP3-1____	-1.13	148822	131485	asparagine utilization	L-asparaginase II
YML029W	__________	-1.09	167432	153447	unknown	unknown
YMR257C	PET111____	-1.22	167760	138023	protein synthesis	translation activator of COX2
YNL314W	DAL82_____	-1.05	248214	236021	transcription	activator of allantoin catabolic genes
YOR054C	__________	-1.05	623102	594360	unknown	unknown
YPL032C	SVL3______	-1.21	196703	162950	unknown	unknown; styryl dye vacuolar localization
YPR127W	__________	+1.11	249344	275900	unknown	unknown; similar to auxin-induced protein PIR:S16390
YBR103W	SIF2______	+1.03	216338	221747	silencing (telomere)(putative)	unknown
YCR040W	MATALPHA1_	+1.06	108349	114439	transcription	alpha-specific gene activator
YDL222C	__________	-1.20	170061	141615	unknown	unknown; similar to Sur7p
YDR341C	__________	-1.27	1250164	981600	protein synthesis	tRNA synthetase, arginine
YER043C	SAH1______	-1.29	3040369	2363592	methionine biosynthesis	S-adenosyl-L-homocysteine hydrolase
YGL032C	AGA2______	-1.14	143242	126130	mating	a-agglutinin binding subunit
YGR143W	SKN1______	-1.05	145263	137808	cell wall biogenesis	(1->6)-beta-glucan synthase subunit
YHR156C	__________	-1.01	179091	177735	unknown	unknown
YJL032W	__________	+1.39	243660	339289	unknown	unknown
YKL031W	__________	-1.06	137471	129235	unknown	unknown
YLL032C	__________	+1.04	273134	283639	unknown	unknown
YLR337C	VRP1______	+1.06	1032573	1095485	cytoskeleton	verprolin
YMR074C	__________	+1.08	934433	1011298	unknown	unknown
YNL124W	__________	-1.26	1398990	1112913	unknown	unknown
YOL032W	__________	-1.06	242771	227966	unknown	unknown
YOR242C	SSP2______	-1.04	237424	228177	sporulation	unknown; similar to class II family of aminoacyl-tRNA synthetases
YPL221W	BOP1______	+1.27	324904	413266	unknown	unknown; bypass of PAM1
YBL042C	FUI1______	+1.03	306754	316808	transport	uridine permease
YDL044C	MTF2______	+1.11	93264	103870	mRNA splicing, mitochondrial	unknown
YDR172W	SUP35_____	-1.11	1034726	933623	protein synthesis	translation release factor
YDR543C	__________	+1.10	124484	136436	unknown	unknown; similar to other subtelomerically-encoded proteins
YFL035C	__________	+1.17	402364	469375
YGL235W	__________	-1.10	121508	110438	unknown	unknown
YHL039W	__________	-1.06	559370	527546	unknown	unknown
YIL134W	FLX1______	-1.05	240190	229134	transport	FAD mitochondrial carrier
YJR012C	__________	+1.10	211866	233241	unknown	unknown
YKR008W	RSC4______	-1.12	299025	267758	chromatin structure	chromatin remodeling complex subunit
YLR165C	__________	+1.14	170366	193403	unknown	unknown
YMR269W	__________	-1.20	461333	384108	unknown	unknown
YNL326C	__________	+1.09	257418	279406	unknown	unknown; similar to Akr1p and Ydr126p
YOR066W	__________	-1.18	246761	208903	unknown	unknown
YPL044C	__________	-2.06	296679	143762	unknown	unknown
YBR114W	RAD16_____	+1.07	165230	177469	DNA repair, nucleotide excision	NEF4 component
YCR052W	RSC6______	-1.14	374332	328979	chromatin structure	chromatin remodeling complex subunit
YDL234C	GYP7______	+1.24	169321	209423	vacuole inheritance	GTPase-activating protein for Ypt7p
YDR353W	TRR1______	+1.07	1368972	1464297	pyrimidine metabolism	thioredoxin reductase
YER053C	__________	+1.38	262602	363059	unknown	unknown; similar to C. elegans mitochondrial phosphate
YGL044C	RNA15_____	-1.09	382448	351832	mRNA 3'-end processing	cleavage/polyadenylation factor CF I component
YGR155W	CYS4______	-1.14	2000104	1747077	methionine biosynthesis	cystathionine beta-synthase
YHR168W	__________	-1.25	221606	177029	unknown	unknown
YJL045W	__________	-1.49	233999	157221	unknown	unknown; similar to succinate dehydrogenase flavoprotein
YKL042W	SPC42_____	-1.04	103205	99531	cytoskeleton	spindle pole body component
YLL044W	__________	-2.06	6095167	2957768	unknown	unknown
YLR349W	__________	-1.16	196043	169586	unknown	unknown
YNL136W	__________	-1.02	364757	355881	unknown	unknown; similar to mature-parasite-infected
YOL044W	PEX15_____	-1.01	193717	191635	peroxisome biogenesis	integral membrane protein
YOR254C	SEC63_____	-1.05	1500546	1422449	secretion	ER protein translocation subcomplex subunit
YPL233W	__________	+1.03	249536	256920	unknown	unknown
YBL054W	__________	+1.07	145159	155569	unknown	unknown
YDL056W	MBP1______	+1.02	246867	251008	cell cycle	transcription factor
YDR183W	PLP1______	+1.19	223486	265330	unknown	unknown; similar to phosducin
YFL047W	__________	-1.12	207456	185538	unknown	unknown; similar to Rga2p
YGL247W	__________	+1.14	193385	220148	unknown	unknown
YHL050C	__________	+1.06	1454585	1541764	unknown	unknown; similar to other subtelomerically-encoded proteins
YIL146C	ECM37_____	-1.05	188155	179633	cell wall biogenesis	unknown
YJR024C	__________	-1.09	544535	499943	unknown	unknown
YKR020W	__________	-1.02	243303	237629	unknown	unknown
YLR177W	__________	+1.26	702080	885595	unknown	unknown
YML048W	GSF2______	-1.14	311487	272366	glucose repression	unknown
YMR281W	GPI12_____	+1.06	309405	327520	protein processing (putative)	N-acetylglucosaminylphosphatidylinositol de-N-acetylase
YNL338W	__________	-1.13	426341	377091	unknown	unknown
YOR078W	__________	-1.06	1403468	1326427	unknown	unknown
YPL056C	__________	-1.14	198216	173967	unknown	unknown
YPR149W	NCE102____	-1.46	729151	500286	secretion, non-classical	unknown
YBR126C	TPS1______	+1.15	564364	650238	trehalose metabolism	trehalose-6-phosphate synthas
YCR064C	__________	+1.04	125811	130396	unknown	unknown
YDL246C	__________	+1.33	153229	203223	unknown	unknown; similar to Sor1p (SOR1 and YDL246C code for nearly
YDR365C	__________	-1.25	859860	685699	unknown	unknown
YER063W	THO1______	+1.05	721935	757946	transcription (putative)	unknown
YGL056C	SDS23_____	-1.04	497373	479125	unknown	unknown; similar to S. pombe sds23
YGR163W	GTR2______	+1.07	484467	520644	signaling (putative)	small GTPase (putative)
YHR180W	__________	+1.12	166368	187014	unknown	unknown
YJL057C	IKS1______	+1.07	196459	210524	signaling (putative)	protein kinase
YKL054C	VID31_____	-1.12	691203	618703	vacuolar protein targeting (putative)	unknown
YLL056C	__________	-1.11	748595	676141	unknown	unknown; similar to Y. pseudotuberculosis CDP-3,
YLR361C	__________	+1.01	225308	227633	unknown	unknown
YMR096W	SNZ1______	-1.07	254453	238256	unknown	unknown; induced in stationary phase
YNL148C	ALF1______	-1.00	131286	130802	protein folding	alpha-tubulin foldin
YOL054W	__________	+1.04	361761	377261	unknown	unknown
YOR266W	PNT1______	+1.03	361451	373102	pentamidine resistance	unknown
YPL245W	__________	-1.17	544828	467021	unknown	unknown
YBL066C	SEF1______	+1.08	105961	114889	transcription	(putative) transcription factor
YDL068W	__________	+1.07	140263	150198	unknown	unknown
YDR195W	REF2______	-1.06	167781	158106	mRNA 3'-end processing	unknown
YFL059W	SNZ3______	+1.20	224088	268193	unknown	unknown; induced in stationary phase
YGL259W	YPS5______	-1.59	248868	156259	protein degradation	GPI-anchored aspartic protease
YHR010W	RPL27A____	+1.23	15394892	18926386	protein synthesis	ribosomal protein L27A

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YIL157C	__________	-1.13	563049	498571	unknown	unknown
YJR035W	RAD26_____	+1.02	463183	473533	DNA repair	putative helicase
YKR032W	__________	-1.06	181670	171066	unknown	unknown
YLR189C	UGT51_____	+1.04	149659	155082	sterol metabolism	UDP-glycosyltransferases
YML059C	__________	-1.07	490564	457360	unknown	unknown
YNR011C	PRP2______	-1.20	374057	310763	mRNA splicing	RNA helicase, putative
YOR090C	PTC5______	+1.01	289268	291424	unknown	protein phosphatase type 2C
YPL066W	__________	+1.32	462100	608597	unknown	unknown
YBR138C	HDR1______	+1.12	157650	176911	meiosis	unknown
YCR075C	ERS1______	-1.04	213812	205370	secretion (putative)	unknown; suppresses erd1 mutation
YDR010C	__________	+1.04	114523	119172	unknown	unknown
YDR375C	BCS1______	+1.15	212377	243709	respiration	cyt. c iron-sulfur subunit expression
YER072W	NRF1______	+1.86	2350052	4365940	signaling, polarized growth (putative)	negative regulator of Cdc42p
YGL068W	__________	+1.04	939389	976199	unknown	unknown; similar to ribosomal proteins
YGR175C	ERG1______	-1.02	2115126	2070311	sterol metabolism	squalene monooxygenase
YHR192W	__________	+1.07	517471	554283	unknown	unknown
YJL069C	__________	-1.34	516928	384355	unknown	unknown
YKL066W	__________	+1.01	128511	129850	unknown	unknown
YLR001C	__________	+1.10	728262	798091	unknown	unknown
YLR373C	VID22_____	-1.08	184073	169772	vacolar protein targeting (putative)	unknown
YMR108W	ILV2______	-1.48	872294	589516	isoleucine and valine biosynthesis	acetolactate synthase
YNL160W	YGP1______	+4.06	332253	1348830	diauxic shift	unknown; response to nutrient limitation
YOL066C	RIB2______	+1.01	238059	241629	riboflavin biosynthesis	DRAP deaminase
YOR278W	HEM4______	-1.04	332749	318518	heme biosynthesis	uroporphyrinogen III synthase
YPL256C	CLN2______	+1.08	607599	655155	cell cycle	G1/S cyclin
YMR323W	__________	-1.54	236095	153186	unknown	unknown; similar to enolases (phosphopyruvate hydratase)
YBL078C	AUT7______	+1.29	150242	193565	autophagy	microtubule-associated protein (putative)
YDL080C	THI3______	-1.14	145084	127100	thiamine metabolism	alpha-ketoisocaproate carboxylase
YDR207C	UME6______	-1.31	245066	187209	meiosis	transcription factor
YFR003C	__________	+1.23	315583	389417	unknown	unknown
YGR008C	STF2______	+1.82	284950	517239	ATP synthesis	ATPase stabilizing factor
YIL169C	__________	-1.08	1054814	976095	unknown	unknown
YJR047C	ANB1______	-1.25	11375189	9073980	protein synthesis	translation initiation factor eIF5A
YKR044W	__________	-1.18	527253	447411	unknown	unknown
YLR201C	__________	+1.26	290376	365498	unknown	unknown
YML071C	__________	-1.12	320970	285471	unknown	unknown
YMR303C	ADH2______	-1.46	15585444	10694042	glycolysis	alcohol dehydrogenase II
YNR023W	SNF12_____	-1.26	409901	326457	transcription	component of SWI/SNF global activator complex
YOR102W	__________	+1.23	749838	923099	unknown	unknown
YPL078C	ATP4______	+1.10	1292947	1415816	ATP synthesis	ATPase; F0-ATP synthase subunit 4
YPR169W	__________	-1.24	1547893	1252897	unknown	unknown
YBR150C	TBS1______	+1.08	223785	240985	drug resistance (putative)	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YDR022C	CIS1______	+1.11	135445	149691	microtubule assembly	cik1 suppressor
YDR387C	__________	+1.04	172246	179994	unknown	unknown; similar to Itr1p and Itr2p
YER084W	__________	-1.17	127358	108777	unknown	unknown
YGL080W	__________	+1.23	269461	330479	unknown	unknown
YGR187C	HGH1______	-1.16	876295	754271	unknown	unknown; similar to human Hmg1p and Hmg2p
YHR204W	__________	-1.23	367871	298332	unknown	unknown; similar to alpha-mannosidase and other glycosyl
YJL081C	ARP4______	-1.11	487261	438961	cytoskeleton	actin-related protein
YKL078W	__________	-1.36	286209	210629	unknown	putative RNA helicase
YLR013W	GAT3______	-1.09	131080	120248	transcription (putative)	DNA binding protein, GATA family
YLR385C	__________	+1.02	94586	96948	unknown	unknown
YNL172W	APC1______	-1.09	108882	100133	mitosis	anaphase-promoting complex subunit
YOL078W	__________	-1.05	154555	146627	unknown	unknown
YOR290C	SNF2______	+1.01	615463	618812	transcription	component of SWI/SNF global activator complex
YPL266W	DIM1______	-1.31	1329931	1014434	rRNA processing, 18S	dimethyladenosine transferase
YBL090W	MRP21_____	+1.02	323643	331265	protein synthesis	ribosomal protein, mitochondrial
YDL092W	SRP14_____	+1.10	585717	645111	secretion	signal recognition particle subunit
YDR215C	__________	+1.07	131557	140387	unknown	unknown
YFR015C	GSY1______	+1.03	149459	153851	glycogen metabolism	glycogen synthase
YGR020C	VMA7______	+1.17	693223	808277	vacuolar acidification	vacuolar H+-ATPase V1 domain 14 kDa subunit
YHR033W	__________	-1.04	165110	158150	unknown	unknown; similar to Pro1p
YIR003W	__________	-1.29	310746	241688	unknown	unknown; similar to E. coli and Bacillus subtilis MinD, has
YJR059W	PTK2______	+1.06	288675	306665	polyamine transport	ser/thr protein kinase
YKR056W	RNC1______	-1.32	553116	419591	unknown	endo-exonuclease
YLR213C	CRR1______	-1.24	231702	187079	unknown	unknown; sporulation specific, related to Crh1p
YML083C	__________	-1.48	260364	175954	unknown	unknown
YMR313C	__________	-1.08	511043	474384	unknown	unknown
YNR035C	ARC35_____	-1.01	957285	950618	cytoskeleton	cortical actin patch integrity
YOR114W	__________	-1.17	292941	249777	unknown	unknown
YPL090C	RPS6A_____	+1.21	15744689	19074652	protein synthesis	ribosomal protein S6A
YPR181C	SEC23_____	-1.40	598277	427429	secretion	vesicle coat component
YBR162C	__________	-1.00	3129914	3116972	unknown	unknown; similar to Aga1p
YCR098C	GIT1______	-1.07	181298	169292	unknown	unknown; similar to phosphate transporter
YDR034C	LYS14_____	-1.11	281718	254744	lysine biosynthesis	transcription factor
YDR399W	HPT1______	+1.01	1693358	1706827	purine biosynthesis	hypoxanthine guanine phosphoribosyl transferase
YER094C	PUP3______	+1.09	1044637	1140872	protein degradation	20S proteasome subunit (beta3
YGL092W	NUP145____	-1.28	331709	258245	nuclear protein targeting	nuclear pore protein
YGR199W	PMT6______	-1.09	358800	330501	protein glycosylation	putative O-mannosyltransferase
YJL093C	TOK1______	-1.05	230140	219466	transport	outward-rectifier potassium channel
YKL090W	__________	-1.10	214322	194662	unknown	unknown
YLR025W	SNF7______	+1.07	491642	527783	glucose derepression	unknown
YLR397C	AFG2______	-1.25	258591	207492	unknown	(putative) AAA ATPase
YMR131C	RSA2______	-1.74	997210	573295	ribosome biogenesis	unknown
YNL184C	__________	-1.40	183432	131246	unknown	unknown
YOL090W	MSH2______	-1.06	555092	525508	DNA repair	MutS homolog; mismatch repair
YOR301W	RAX1______	-1.14	189224	166682	cell polarity (putative)	unknown
YPL278C	__________	+1.06	170304	181282	unknown	unknown
YAL010C	MDM10_____	-1.07	136551	127033	mitochondrial biogenesis	(putative) component of actin binding protein complex
YBR174C	__________	-1.13	118693	105170	unknown	unknown
YCRX04W	__________	-1.54	318538	206496
YDR045C	RPC11_____	+1.03	399002	410445	transcription	RNA polymerase III subunit C11
YDR412W	__________	-2.13	625992	293819	unknown	unknown
YER107C	GLE2______	-1.11	462539	415676	nuclear protein targeting	nuclear pore protein
YGL105W	ARC1______	-1.19	1799798	1517183	tRNA aminoacylation	G4 nucleic acid binding protein
YGR212W	__________	+1.05	136627	143350	unknown	unknown
YIL009W	FAA3______	-1.37	624045	456754	fatty acid metabolism	acyl CoA synthase
YJL106W	IME2______	+1.00	141639	141724	signaling, meiosis pathway	serine/threonine protein kinase
YKL102C	__________	+1.08	119750	128813	unknown	unknown; similar to potato lipoxygenase
YLR036C	__________	+1.07	153668	164524	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YLR410W	VIP1______	+1.01	108063	109355	unknown	unknown
YNL197C	WHI3______	-1.17	171990	147269	cell size	unknown
YOL103W	ITR2______	-1.16	524566	454088	transport	inositol permease
YOR313C	SPS4______	+1.20	210154	251751	sporulation	putative cell wall component
YPR008W	__________	-1.02	151047	148009	unknown	unknown; similar to Cup2p and Candida albicans
YBL101W	__________	-1.56	6001045	3858883	unknown	unknown
YCL008C	STP22_____	-1.27	207025	163129	vacuolar protein targeting	unknown; similar to Tsg101 tumor susceptibility gene
YDL105W	QRI2______	-1.10	152561	138666	unknown	unknown
YDR228C	PCF11_____	+1.02	887859	901357	mRNA 3'-end processing	cleavage/polyadenylation factor CF I component
YEL009C	GCN4______	-1.06	4214981	3968399	amino acid, purine biosynthesis	transcription factor
YFR028C	CDC14_____	-1.28	459030	357315	mitosis	protein phosphatase
YGR031W	__________	-1.34	206049	153541	unknown	unknown
YHR045W	__________	-1.05	353883	338374	unknown	unknown
YIR016W	__________	+1.10	460485	507379	unknown	unknown
YJR072C	__________	-1.23	593918	483753	unknown	unknown
YKR069W	MET1______	+1.12	173165	193487	methionine biosynthesis	siroheme synthase
YLR226W	BUR2______	-1.13	194616	172317	unknown	unknown
YML095C	RAD10_____	-1.02	242133	238491	DNA repair	ssDNA endonuclease
YNL009W	IDP3______	+1.03	140077	143753	TCA cycle	isocitrate dehydrogenase
YNR048W	__________	-1.04	235161	225078	unknown	unknown
YOR127W	RGA1______	+1.06	414598	439405	bud site selection	putative GTPase-activating protein (GAP) for Cdc42p or Rho1p
YPL103C	__________	-1.08	191177	177326	unknown	unknown
YPR194C	__________	+1.44	311831	449718	unknown	sexual differentiation protein family
YAL022C	FUN26_____	-1.12	225971	202533	unknown	unknown
YBR186W	PCH2______	+1.01	113160	114324	meiosis, checkpoint	unknown
YCRX16C	__________	-1.29	2287027	1776582
YDR057W	__________	-1.06	217868	204638	unknown	unknown
YDR424C	DYN2______	+1.18	293918	347023	cytoskeleton	dynein light chain
YER119C	__________	-1.02	214005	210301	unknown	unknown
YGL117W	__________	+1.10	172196	189076	unknown	unknown
YGR224W	AZR1______	+1.03	135973	140184	drug resistance (putative)	unknown; major facilitator superfamily
YIL020C	HIS6______	-1.14	568165	499760	histidine biosynthesis	Phosphoribosyl imidazolecarboxamide isomerase
YJL118W	__________	-1.00	115611	115182	unknown	unknown
YKL114C	APN1______	+1.07	481069	515072	DNA repair	apurinic/apyrimidinic endonuclease
YLR048W	RPS0B_____	-1.17	10573154	9062242	protein synthesis	ribosomal protein S0B
YLR420W	URA4______	-1.05	1685761	1611865	pyrimidine biosynthesis	dihydrooratase
YMR154C	RIM13_____	-1.03	222962	215786	sporulation	proteolytic processing of Rim1p
YNL209W	SSB2______	-1.71	10393837	6065794	translation	cytosolic HSP70
YOL113W	SKM1______	+1.18	237443	281233	unknown	protein kinase
YOR325W	__________	-1.26	160828	127874	unknown	unknown
YPR020W	ATP20_____	+1.20	655322	785353	ATP synthesis	mitochondrial ATP synthase subunit
YBL113C	__________	+1.00	1445312	1448511	unknown	unknown
YCL021W	__________	-1.16	1145874	991688
YDL117W	CYK3______	-1.09	213396	195488	cytokinesis (putative)	unknown
YEL020C	__________	-1.04	162882	155987	unknown	unknown; similar to oxalyl-CoA decarboxylase from
YFR037C	RSC8______	-1.21	888720	735561	chromatin structure	chromatin remodeling complex subunit
YHR056C	__________	-1.14	584242	514699	unknown	putative transcriptional regulator
YIR025W	__________	-1.06	263847	249774	unknown	unknown
YJR085C	__________	+1.36	729734	996050	unknown	unknown
YKR081C	__________	-1.20	1378668	1144534	unknown	unknown
YLR236C	__________	-1.08	137945	128148	unknown	unknown
YML105C	SEC65_____	-1.02	950521	935825	secretion	signal recognition particle subunit
YNL021W	HDA1______	-1.07	184662	173074	chromatin structure	histone deacetylase
YNR060W	FRE4______	-1.22	232624	191355	unknown	unknown; similar to ferric reductases Fre1p and Fre2p
YOR139C	__________	-1.16	164770	142044	unknown	unknown
YPL115C	BEM3______	-1.15	394658	344488	bud emergence	GTPase-activating protein for Cdc42p
YAL033W	POP5______	+1.01	215239	218039	tRNA processing	RNase P and RNase MRP subunit
YBR198C	TAF90_____	-1.16	276785	239630	transcription	TFIID 90 kD subunit
YDR069C	DOA4______	-1.02	232675	229226	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YDR436W	PPZ2______	-1.01	174332	173016	stress response	ser/thr phosphatase
YER130C	__________	+1.19	276685	330305	unknown	unknown
YGL129C	__________	+1.07	94983	102107	unknown	unknown; similar to crayfish 1,3-beta-D-glucan-binding
YGR236C	__________	-1.11	156671	141148	unknown	unknown
YIL032C	__________	-1.13	186437	164385	unknown	unknown
YJL130C	URA2______	-1.51	4033861	2673695	pyrimidine biosynthesis	carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase
YKL126W	YPK1______	+1.11	372164	413314	unknown	protein kinase
YLR060W	FRS1______	-1.18	1143344	967434	protein synthesis	tRNA synthetase, phenylalanyl, subunit
YLR430W	SEN1______	-1.17	666358	568939	tRNA splicing	RNA helicase, putative
YMR165C	SMP2______	-1.04	112549	108717	respiration; plasmid maintenance	unknown
YNL221C	POP1______	-1.33	514785	386753	rRNA and tRNA processing	RNase P and RNase MRP subunit
YOL125W	__________	-1.30	435109	335195	unknown	unknown
YOR337W	TEA1______	-1.09	140831	129770	transcription	Ty1 enhancer activator
YPR032W	SRO7______	-1.05	120531	114411	signaling (putative)	suppresses rho3 mutant
YBR012C	__________	-1.15	191818	166258	unknown	unknown
YCL033C	__________	+1.24	311808	387240	unknown	unknown; similar to Neisseria pilin
YDL129W	__________	+1.00	152381	152734	unknown	unknown
YDR252W	BTT1______	+1.06	118056	124836	transcription	negative regulator of RNA polymerase II
YEL032W	MCM3______	+1.02	106298	108219	DNA replication	MCM initiator complex
YFR049W	YMR31_____	+1.18	309295	364260	protein synthesis	ribosomal protein, mitochondrial
YGR050C	__________	+1.04	146543	153117	unknown	unknown
YHR066W	SSF1______	-1.11	969886	870463	mating (putative)	unknown
YIR037W	HYR1______	+1.33	767818	1021368	oxidative stress response	glutathione peroxidase
YJR096W	__________	+1.10	173463	190322	unknown	unknown; similar to aldolase reductase
YKR093W	PTR2______	-1.02	393357	384034	transport	small peptide permease
YLR248W	RCK2______	-1.18	380752	321713	unknown	Ca/calmodulin-dependent protein kinase
YNL033W	__________	-1.17	144849	124010	unknown	unknown
YNR072W	HXT17_____	-1.12	165145	147283	transport	hexose permease
YOR149C	SMP3______	-1.19	209568	176462	plasmid maintenance	integral membrane, protein kinase C pathway protein
YPL127C	HHO1______	-1.07	983638	921001	chromatin structure	histone H1
YBR210W	__________	+1.06	245764	261692	unknown	unknown
YDR081C	PDC2______	-1.06	170870	160774	glycolysis	regulator of pyruvate decarboxylase genes
YDR448W	ADA2______	+1.16	135325	157480	chromatin structure	histone acetyltransferase complex subunit
YER140W	__________	+1.07	177852	190985	unknown	unknown
YGL141W	HUL5______	+1.09	95343	103783	protein degradation, ubiquitin mediated	ubiquitin-protein ligase (E3)
YGR248W	SOL4______	+1.16	135987	157229	unknown	unknown; similar to Sol3p
YIL044C	AGE2______	+1.06	438028	464524	secretion	GTPase activating protein for ARFs
YJL142C	__________	+1.40	269178	376363	unknown	unknown
YKL138C	MRPL31____	+1.07	297822	320128	protein synthesis	ribosomal protein, mitochondrial L31
YLR072W	__________	-1.05	128542	122564	unknown	unknown
YLR442C	SIR3______	-1.04	397292	381837	silencing	nuclear protein, reulator of silencing at HML, HMR, telomeres

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL233W	BNI4______	-1.04	309500	297045	cytokinesis	may link chitin synthase to septins
YOL137W	__________	-1.03	276784	269842	unknown	major facilitator superfamily
YOR347C	PYK2______	-1.74	499946	286551	glycolysis	pyruvate kinase
YPR044C	__________	+1.20	15799800	19019498	unknown	unknown
YBR022W	__________	+1.12	259118	291320	unknown	unknown
YCL045C	__________	-1.10	641943	584790	unknown	unknown
YDL139C	SCM3______	+1.08	161467	174597	mitosis, chromosome segregation (putative)	unknown
YEL044W	__________	+1.05	196905	207278	unknown	unknown
YGR062C	COX18_____	+1.11	171356	190450	respiration	required for activity of mitochondrial cytochrome oxidase
YHR077C	NMD2______	-1.04	407987	393198	mRNA decay, nonsense-mediated	Nam7p/Upf1p-interacting protein
YJR108W	ABM1______	-1.04	122253	118068	cytoskeleton (putative)	unknown
YKR105C	__________	-1.20	190988	159436	unknown	major facilitator superfamily
YLR257W	__________	+1.32	688614	912168	unknown	unknown
YML128C	__________	+1.24	192856	238430	unknown	unknown
YNL043C	__________	+1.18	821780	967605	unknown	unknown
YOR161C	__________	-1.06	287897	272751	unknown	unknown
YPL139C	UME1______	-1.07	279372	260725	meiosis	transcription factor
YBR222C	FAT2______	+1.22	158693	193362	transport	peroxisomal (putative) fatty acid transporter
YDR093W	__________	+1.05	1691486	1771715	unknown	unknown; similar to members of Drs2p family of P-type
YDR460W	TFB3______	-1.01	224342	221420	transcription	TFIIH 38 kD subunit
YER150W	SPI1______	+1.87	209332	391504	unknown	unknown; similar to Sed1p; induced in stationary phase
YGL153W	PEX14_____	+1.07	190208	203314	peroxisomal protein targeting	peroxisomal import machinery component
YGR260W	TNA1______	-1.03	838773	816627	transport	nicotinic acid permease
YIL056W	__________	-1.07	287231	268040	unknown	unknown
YJL154C	VPS35_____	+1.11	318380	352729	vacuolar protein targeting	peripheral membrane protein
YKL150W	MCR1______	+1.42	587260	832788	electron carrier	cytochrome-b5 reductase
YLR084C	RAX2______	-1.11	321920	289992	cell polarity (putative)	unknown
YLR454W	__________	-1.19	1943582	1627153	unknown	unknown
YMR187C	__________	+1.08	194819	210357	unknown	unknown
YNL245C	__________	+1.03	369784	380461	unknown	unknown
YOL149W	DCP1______	+1.12	713920	798654	mRNA decay	decapping enzyme
YOR359W	__________	-1.12	159637	142094	unknown	unknown
YPR056W	TFB4______	-1.05	307296	293995	transcription	TFIIH 37 kD subunit
YBR034C	HMT1______	-1.24	937789	758285	protein processing	arginine methyltransferase
YCL057W	PRD1______	-1.24	527636	425701	protein degradation	proteinase yscD
YDL151C	__________	-1.77	270199	152802	unknown	unknown
YDR272W	GLO2______	+1.13	541824	610290	methylglyoxal resistance	glyoxalase II
YEL056W	HAT2______	-1.05	391629	371423	chromatin structure	histone acetyltransferase complex subunit
YGR074W	SMD1______	-1.02	334074	328050	mRNA splicing	U6 snRNP protein
YHR088W	RPF1______	-1.15	733207	636602	unknown	unknown
YJR120W	__________	-1.22	139615	114784	unknown	unknown
YLR268W	SEC22_____	+1.11	746479	829171	secretion	ER-to-Golgi v-SNARE
YMR007W	__________	+1.55	154475	239045	unknown	unknown
YOR173W	__________	+1.15	121548	139306	unknown	unknown
YPL151C	PRP46_____	-1.06	317409	300419	mRNA splicing	unknown
YAL067C	SEO1______	+1.17	91302	107088	drug resistance	suppressor of sulfoxyde ethionine
YBR234C	ARC40_____	+1.11	105568	116901	cytoskeleton	Arp2/3 complex subunit
YDR103W	STE5______	-1.02	195540	191264	signaling, pheromone pathway	scaffold protein for MAP kinase cascade
YDR472W	TRS31_____	+1.11	470955	521484	secretion (putative)	transport protein particle (TRAPP) subunit, 31 kD
YER160C	__________	-1.13	158299	139503	unknown	unknown
YGL165C	__________	+1.20	312278	375951	unknown	unknown
YGR272C	__________	-1.27	585211	462240	unknown	unknown
YIL067C	__________	-1.16	272948	235332	unknown	unknown
YJL166W	QCR8______	+1.49	1214153	1809679	oxidative phosphorylation	ubiquinol--cytochrome-c reductase subunit VIII
YKL162C	__________	-1.01	149058	147743	unknown	unknown
YLR096W	KIN2______	-1.25	657174	527720	unknown	protein kinase
YLR466W	YRF1-4____	+1.08	1886005	2037116	unknown	Y' helicase (subtelomerically-encoded)
YMR198W	CIK1______	-1.01	186046	184347	cytoskeleton	spindle pole body associated protein
YNL257C	SIP3______	+1.08	123058	132886	glucose derepression	(putative) transcriptional activator
YOL161C	__________	+1.11	322312	356800	unknown	unknown; similar to PAU1 family
YOR371C	__________	-1.12	178618	159116	unknown	unknown
YPR068C	HOS1______	+1.04	115274	120231	unknown	unknown; similar to Hda1p, Rpd3p, Hos2p, and Hos3p
YBR046C	ZTA1______	+1.18	118064	138811	unknown	putative quinone oxidoreductase
YCL069W	__________	-1.02	124985	123106	unknown	major facilitator superfamily
YDL163W	__________	-1.00	104390	104220	unknown	unknown
YDR284C	DPP1______	+1.22	276773	337357	phospholipid metabolism	diacylglycerol pyrophosphate phosphatase
YEL067C	__________	+1.04	134840	140057	unknown	unknown
YGR086C	__________	+1.18	3047490	3610359	unknown	unknown
YHR100C	__________	-1.07	506140	471704	unknown	unknown
YJR132W	NMD5______	-1.30	498501	382212	unknown	Nam7p/Upf1p-interacting protein
YLR280C	__________	+1.02	103845	105944	unknown	unknown
YMR019W	STB4______	-1.00	182855	182114	transcription	Sin3-binding protein
YNL065W	__________	+1.16	278580	323737	unknown	major facilitator superfamily
YOR185C	GSP2______	-1.17	2490755	2120165	nuclear organization	GTPase; ran homolog
YPL163C	SVS1______	+1.46	637647	930210	vanadate resistance	unknown
YAR019C	CDC15_____	+1.03	211565	217187	cell cycle	protein kinase
YBR246W	__________	-1.05	234216	223381	unknown	unknown
YDR115W	__________	+1.14	220836	250650	unknown	unknown; similar to prokaryotic L34 ribosomal protein
YDR484W	SAC2______	+1.12	201133	225788	cytoskeleton	suppressor of actin mutation
YER171W	RAD3______	-1.09	268328	246527	transcription; DNA repair	TFIIH subunit
YGL177W	__________	+1.16	145311	167862	unknown	unknown
YGR284C	ERV29_____	+1.11	873755	971709	secretion (putative)	unknown; transport vesicle protein
YIL077C	__________	+1.05	371718	388571	unknown	unknown
YJL178C	__________	-1.22	1138051	934060	unknown	unknown
YKL174C	__________	-1.03	321533	312859	unknown	unknown; similar to Hnm1p and other permeases
YLR108C	__________	+1.10	129959	142719	unknown	unknown
YMR210W	__________	-1.15	943278	818683	unknown	unknown
YNL269W	__________	+1.25	218447	272531	unknown	unknown
YOR007C	SGT2______	-1.38	2958635	2144479	unknown	unknown
YOR383C	__________	+1.21	636992	771039	unknown	unknown
YPR080W	TEF1______	+1.20	15958128	19165954	protein synthesis	translation elongation factor EF-1 alph
YBR058C	UBP14_____	-1.09	461333	423493	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YCLX08C	__________	+1.08	126851	137403
YDL175C	__________	+1.02	211103	215846	unknown	unknown
YDR296W	MHR1______	+1.10	205589	226819	recombination, mitochondrial	unknown
YER001W	MNN1______	+1.30	266428	345529	protein glycosylation	alpha-1,3-mannosyltransferase
YGR098C	ESP1______	+1.01	108866	109553	cytoskeleton	spindle pole body duplication
YHR112C	__________	+1.13	350367	397487	unknown	unknown; similar to cystathionine gamma-synthase Str2p
YJR144W	MGM101____	+1.13	1025539	1154962	mitochondrial genome maintenance	(putative) nucleic acid interactor
YLR291C	GCD7______	-1.18	674938	570018	protein synthesis	translation initiation factor eIF2b subunit

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YMR031C	__________	-1.29	328266	254156	unknown	unknown
YNL077W	__________	-1.08	270621	249511	unknown	unknown; similar to E. coli DnaJ and other DnaJ-like proteins
YOR195W	SLK19_____	-1.20	785248	654844	mitosis	unknown; synthetic lethal with kar3
YPL175W	SPT14_____	-1.20	318541	266279	protein processing	N-acetylglucosaminyltransferase (GPI anchor synthesis)
YAR042W	SWH1______	-1.03	126938	122814	unknown	unknown; similar to mammalian oxysterol-binding protein
YBR258C	__________	+1.10	198999	219492	unknown	unknown
YDR127W	ARO1______	+1.00	1190257	1191860	aromatic amino acid biosynthesis	pentafunctional enzyme
YDR496C	__________	-1.22	722284	593880	unknown	unknown
YER182W	__________	+1.25	288846	360993	unknown	unknown
YGL189C	RPS26A____	+1.24	15418516	19068851	protein synthesis	ribosomal protein S26A
YGR296W	YRF1-3____	+1.20	474640	568371	unknown	Y' helicase (subtelomerically-encoded)
YIL088C	__________	+1.12	375016	419096	unknown	unknown; similar to members of the major facilitator
YJL190C	RPS22A____	+1.21	15588425	18848439	protein synthesis	ribosomal protein S22A
YKL186C	MTR2______	+1.07	916000	984087	mRNA export	unknown
YLR120C	YPS1______	+1.06	229482	243316	protein processing	GPI-anchored aspartic protease
YMR222C	__________	-1.10	317897	289833	unknown	unknown; similar to S. pombe DFR1, dihydrofolate reductase
YNL281W	HCH1______	-1.05	1032968	986207	stress response (putative)	unknown; overexpression suppresses hsp82 mutation
YOR019W	__________	-1.01	221537	220116	unknown	unknown
YPR092W	__________	-1.06	156173	147273	unknown	unknown
YBR070C	__________	+1.21	237715	287272	stress response	osmotolerance protein (putative)
YCR008W	SAT4______	-1.02	268376	264352	salt tolerance	protein kinase
YDL187C	__________	-1.05	119270	113534	unknown	unknown
YDR308C	SRB7______	+1.07	220380	235429	transcription	RNA polymerase II mediator subunit
YER011W	TIR1______	+1.68	1948841	3280813	stress response (putative)	cell wall protein
YHR124W	NDT80_____	-1.70	848094	500100	meiosis	transcription factor
YJR156C	THI11_____	+1.02	186363	189167	pyrimidine biosynthesis	thiamine regulated gene
YLR303W	MET17_____	+2.24	475139	1063026	methionine biosynthesis	O-acetylhomoserine sulfhydrylase
YMR042W	ARG80_____	-1.24	221711	179090	arginine metabolism	transcription factor
YNL089C	__________	+1.08	232115	251695	unknown	unknown
YOR207C	RET1______	-1.01	125156	124175	transcription	RNA polymerase III 130 kD subunit
YPL186C	__________	+1.06	144866	153973	unknown	unknown
YBL007C	SLA1______	-1.33	290055	218227	cytoskeleton	cortical actin assembly
YBR270C	__________	-1.16	137568	118212	unknown	unknown
YDL009C	__________	+1.15	206437	236497	unknown	unknown
YDR139C	RUB1______	-1.05	322137	306576	protein degradation	ubiquitin-like protein
YDR508C	GNP1______	+1.06	344477	365676	transport	glutamine permease
YFL007W	BLM3______	-1.55	237757	153568	drug resustance	unknown; major facilitator superfamily
YGL201C	MCM6______	+1.15	85644	98377	DNA replication	MCM initiator complex
YHL007C	STE20_____	+1.03	265858	273540	signaling, pheromone and pseudohyphal growth pathways	serine-threonine protein kinase
YJL202C	__________	+1.12	242223	270635	unknown	unknown
YKL198C	PTK1______	-1.02	134327	131378	polyamine transport	ser/thr protein kinase
YLR132C	__________	+1.06	113231	119700	unknown	unknown
YMR234W	RNH1______	+1.13	315265	355087	DNA replication (putative)	ribonuclease H
YNL291C	MID1______	-1.02	285934	279747	transport	Ca(2+) channel component
YOR031W	CRS5______	+1.17	229149	268754	Cu2+ ion homeostasis	metallothionein-like protein
YPL009C	__________	-1.00	109275	108958	unknown	unknown
YPR104C	FHL1______	-1.22	426235	349339	transcription	transcriptional activator
YBR082C	UBC4______	+1.06	1237952	1318147	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YCR020C	MAK31_____	-1.19	218486	183799	dsRNA virus propagation	unknown
YDL199C	__________	-1.08	123777	114690	unknown	unknown; similar to members of the sugar permease family
YDR318W	MCM21_____	-1.04	182284	176021	mitosis, chromosome segregation	unknown
YER021W	RPN3______	-1.08	944423	873161	protein degradation	26S proteasome regulatory subunit
YGL009C	LEU1______	-1.39	246685	177148	leucine biosynthesis	3-isopropylmalate dehydratase
YGR120C	SEC35_____	+1.08	234243	253355	secretion	peripheral membrane protein required for ER to Golgi vesicle docking
YHR135C	YCK1______	+1.16	762449	887977	unknown	protein kinase
YJL009W	__________	+1.10	1232675	1356875	unknown	unknown
YKL008C	LAC1______	+1.16	420574	486134	aging	unknown; similar to Lag1p, has 6 potential transmembrane
YLL009C	COX17_____	+1.35	296616	399606	respiration	cytochrome oxidase assembly
YLR314C	CDC3______	+1.11	363757	405400	cytokinesis	septin
YMR052W	FAR3______	+1.16	155669	179998	cell cycle, pheromone arrest	unknown
YNL101W	__________	+1.02	224173	229742	unknown	unknown; similar to members of a putative transporter family
YOL009C	MDM12_____	+1.00	240027	240280	mitochondrial inheritance	transmembrane protein
YOR219C	STE13_____	+1.11	306901	339925	mating	alpha-factor maturation
YPL198W	RPL7B_____	-1.36	5848246	4308982	protein synthesis	ribosomal protein L7B
YAR068W	__________	-1.05	165404	157434	unknown	unknown; similar to ICWP protein
YBL019W	APN2______	-1.15	105176	91812	DNA repair	exonuclease III homolog (AP endonuclease)
YBR282W	MRPL27____	-1.15	277728	240721	protein synthesis	ribosomal protein, mitochondrial L27
YDL021W	GPM2______	+1.18	117017	137887	glycolysis	phosphoglycerate mutase
YDR151C	CTH1______	-1.08	288743	266464	unknown	unknown
YDR520C	__________	-1.06	128358	121551	unknown	unknown; similar to glycosyl hydrolase
YFL016C	MDJ1______	-1.26	309302	244993	protein folding	chaperone; DnaJ homolog
YGL213C	SKI8______	-1.06	507300	478685	meiosis, recombination	antiviral RNA binding protein
YHL017W	__________	-1.10	361243	329588	unknown	unknown; similar to Ptm1p, member of major
YIL111W	COX5B_____	+1.54	212866	327517	oxidative phosphorylation	cytochrome-c oxidase subunit Vb
YJL214W	HXT8______	+1.08	142198	152993	transport	hexose permease
YKL210W	UBA1______	-1.06	302409	285154	protein degradation, ubiquitin-mediated	E1-like (ub.-activating) enzyme
YLR144C	ACF2______	+1.01	208614	210368	cytoskeleton	cortical actin assembly
YML018C	__________	-1.29	1114319	861557	unknown	unknown
YMR245W	__________	+1.04	329132	340921	unknown	unknown
YNL303W	__________	-1.12	796018	710858	unknown	unknown
YOR043W	WHI2______	-1.17	552466	470689	cell size	unknown
YPL021W	ECM23_____	-1.05	121960	116165	cell wall biogenesis (putative)	unknown
YPR116W	__________	-1.03	117618	114516	unknown	unknown
YBR092C	PHO3______	+1.09	175354	190305	thiamine uptake	acid phosphatase, constitutive
YCR029C	__________	+1.06	782213	828921
YDL211C	__________	-1.20	174204	144772	unknown	unknown
YDR330W	__________	-1.22	227960	187256	unknown	unknown; similar to Undulin extracellular matrix
YER033C	ZRG8______	-1.22	170156	139288	unknown	unknown; zinc regulated
YGL021W	ALK1______	-1.03	103091	99712	DNA repair (putative)	DNA damage-responsive protein
YGR132C	PHB1______	-1.03	819631	797113	antiproliferative protein	unknown
YHR145C	__________	+1.00	5412544	5431948	unknown	unknown
YJL021C	__________	+1.21	478418	577258	unknown	unknown
YKL020C	SPT23_____	-1.07	355679	331927	transcription	transcription factor
YLL021W	SPA2______	-1.06	379437	359481	cytoskeleton	cortical actin patch component
YLR326W	__________	+1.18	185708	219347	unknown	unknown
YMR063W	RIM9______	-1.06	130360	122561	sporulation	stimulates expression of IME1
YNL113W	RPC19_____	-1.06	954420	897543	transcription	subunit common to RNA polymerases I and III
YOL021C	DIS3______	+1.01	94094	94821	RNA processing	3'-5' exoribonuclease complex subunit
YOR231W	MKK1______	-1.12	242617	216149	signaling, PKC1 pathway	MAP kinase (mitogen-activated protein kinase)
YPL210C	SRP72_____	-1.12	606001	543040	secretion	signal recognition particle subunit

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YBL031W	SHE1______	-1.05	117321	112094	unknown	overexpression is lethal
YBR294W	SUL1______	-1.00	133702	133355	transport	sulfate permease
YDL033C	__________	-1.10	152506	138045	unknown	unknown; similar to H. influenza protein HI0174
YDR163W	__________	+1.12	290522	325074	unknown	unknown
YDR532C	__________	+1.01	262467	265250	unknown	unknown
YFL026W	STE2______	-1.04	133788	128676	mating	alpha-factor receptor
YGL225W	GOG5______	-1.01	1552847	1544067	protein glycosylation	Golgi GDP-mannose transporter
YHL029C	__________	+1.06	268661	285442	unknown	unknown
YIL123W	SIM1______	-1.08	1368748	1271948	cell cycle	unknown
YJR002W	MPP10_____	-1.48	1273385	861727	rRNA processing	U3 snoRNP protein
YKL222C	__________	-1.19	184777	155842	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YLR156W	__________	+1.07	100424	107362	unknown	unknown
YML030W	__________	+1.02	475207	486762	unknown	unknown
YMR258C	__________	+1.01	234027	237327	unknown	unknown
YNL315C	ATP11_____	+1.00	451314	452125	ATP synthesis	F1F0-ATPase complex assembly protein
YOR055W	__________	-1.10	126068	114706	unknown	unknown
YPL033C	__________	-1.02	127188	124856	unknown	unknown
YPR128C	__________	-1.00	288158	287912	unknown	unknown; similar to ADP/ATP carrier proteins
YBR104W	YMC2______	-1.23	501028	407837	transport	mitochondrial carrier family
YCR041W	__________	+1.14	477322	542983	unknown	unknown
YDL223C	__________	-1.05	142672	135814	unknown	unknown
YDR342C	HXT7______	-1.10	2272536	2068430	transport	hexose permease
YER044C	MEI4______	-1.14	148276	130395	meiosis, chromosome pairing and recombination	unknown
YGL033W	HOP2______	+1.02	125671	128433	meiosis, chromosome pairing (putative)	unknown
YGR144W	THI4______	-1.03	126532	123245	thiamine biosynthesis	unknown; biosynthetic enzyme
YHR157W	REC104____	+1.03	143791	147667	meiosis, recombination	ds break formation complex subunit
YJL033W	HCA4______	-1.31	709952	543326	rRNA processing	RNA helicase
YKL032C	IXR1______	+1.04	1252051	1300019	transcription, oxygen-dependent	HMG-transcription factor
YLL033W	__________	+1.04	174731	181326	unknown	unknown
YLR338W	__________	-1.02	158565	156099	unknown	unknown
YMR075W	__________	+1.02	171600	174338	unknown	unknown
YNL125C	ESBP6_____	-1.10	239943	218324	unknown	unknown; similar to mammalian monocarboxylate transporters
YOL033W	MSE1______	-1.02	219372	215733	protein synthesis	tRNA synthetase, mitochondrial, glutamyl
YOR243C	__________	-1.40	713124	511116	unknown	unknown
YPL222W	__________	-1.04	110458	105977	unknown	unknown
YBL043W	ECM13_____	+1.02	120630	122683	cell wall biogenesis	unknown
YDL045C	FAD1______	+1.06	245895	260525	flavin biosynthesis	flavin adenine dinucleotide (FAD) synthetase
YDR173C	ARG82_____	+1.06	251008	267126	arginine metabolism	transcription factor
YDR544C	__________	+1.18	268594	316092	unknown	unknown
YFL036W	RPO41_____	-1.07	256989	240987	transcription	mitochondrial RNA polymerase
YGL236C	MTO1______	-1.16	194202	166951	salt tolerance (putative)	unknown; similar to E. coli gidA protein
YHL040C	ARN1______	-1.09	226484	207456	unknown	unknown; similar to subtelomerically-encoded proteins
YIL135C	__________	+1.08	101966	109740	unknown	unknown
YJR013W	__________	+1.10	285530	313585	unknown	unknown; similar to human angiotensin II type 1b
YKR009C	FOX2______	+1.07	116335	124571	fatty acid metabolism	peroxisomal beta-oxidation protein
YLR166C	SEC10_____	-1.03	206639	199745	secretion	exocyst complex subunit
YMR270C	RRN9______	-1.05	343938	326899	transcription	component of upstream activation factor complex (UAF)
YNL327W	EGT2______	+1.05	126245	132428	cell cycle	unknown
YOR067C	ALG8______	-1.11	566817	511021	protein glycosylation	glycosyltransferase
YPL045W	VPS16_____	-1.24	313682	253766	vacuolar protein targeting	component of sorting nexin complex
YPR138C	MEP3______	+1.02	482552	492701	transport	ammonia permease
YBR115C	LYS2______	-1.42	505999	356018	lysine biosynthesis	L-aminoadipate-semialdehyde dehydrogenase
YCR053W	THR4______	-1.01	1213475	1200137	threonine biosynthesis	threonine synthase
YDL235C	YPD1______	+1.29	569665	733299	signaling	two-component phosphorelay intermediate
YDR354W	TRP4______	+1.04	443552	459362	tryptophan biosynthesis	anthranilate phosphoribosyltransferase
YER054C	GIP2______	-1.01	8677102	8572521	glucose repression	(putative) Glc7p regulatory subunit
YGL045W	__________	-1.15	229894	200325	unknown	unknown
YGR156W	__________	-1.08	289274	268742	unknown	unknown
YHR169W	DBP8______	-1.17	616481	525365	unknown	RNA helicase
YJL046W	__________	-1.23	321639	262354	unknown	unknown; similar to lipoate-protein ligase A
YKL043W	PHD1______	-1.27	559039	438792	pseudohyphal growth	transcription factor
YLL045C	RPL8B_____	-1.13	14226479	12590438	protein synthesis	ribosomal protein L8B
YLR350W	__________	+1.26	577802	725890	unknown	unknown
YMR086W	__________	-1.03	148944	145002	unknown	unknown
YNL137C	NAM9______	-1.27	340365	268450	protein synthesis	ribosomal protein, mitochondrial S4 (putative)
YOL045W	__________	-1.15	485840	421543	unknown	protein kinase
YOR255W	__________	-1.02	134795	132750	unknown	unknown
YPL234C	TFP3______	+1.03	2239804	2303428	vacuolar acidification	vacuolar H+-ATPase V0 domain 17 KD subunit
YBL055C	__________	+1.09	196768	215049	unknown	unknown
YDL057W	__________	+1.19	131949	157446	unknown	unknown
YDR184C	ATC1______	-1.09	425121	388751	cell polarity	member of Bud6p complex
YFL048C	EMP47_____	+1.14	720686	821479	secretion	unknown; ER/Golgi membrane protein
YGL248W	PDE1______	+1.57	299243	468852	purine metabolism	3',5'-cyclic-nucleotide phosphodiesterase
YHR001W	__________	+1.04	459322	478589	unknown	unknown; similar to Ykr003p and members of the oxysterol-binding protein family
YIL147C	SLN1______	-1.07	1184936	1111430	signaling	two-component pathway
YJR025C	BNA1______	+1.48	395490	584042	nicotinic acid biosynthesis	3-hydroxyanthranilic acid dioxygenase
YKR021W	__________	-1.01	138503	136727	unknown	unknown
YLR178C	TFS1______	+1.35	226609	305932	cell cycle	suppresses cdc25 mutations
YML049C	RSE1______	+1.06	536935	571696	secretion and RNA splicing	unknown
YMR282C	AEP2______	+1.00	271473	272724	protein synthesis	translation of ATP9/OLI1 mRNA
YNL339C	YRF1-6____	+1.09	105766	115272	unknown	Y' helicase (subtelomerically-encoded)
YOR079C	ATX2______	+1.15	377216	432660	oxidative stress response	manganese-trafficking protein
YPL057C	SUR1______	+1.17	279455	326474	sphingolipid metabolism	suppresses cls2-2and rvs161
YPR150W	__________	+1.27	163274	208135	unknown	unknown
YBR127C	VMA2______	-1.40	528071	376991	vacuolar acidification	58 kD regulatory subunit
YCR065W	HCM1______	+1.01	123049	123764	transcription (putative)	forkhead family of DNA-binding proteins
YDL247W	__________	+1.27	86967	110420	unknown	unknown; similar to maltose permeases including Yjr160p,
YER064C	__________	-1.14	244775	215054	unknown	unknown; similar to members of a putative transporter family
YGL057C	__________	+1.09	200141	218242	unknown	unknown
YGR164W	__________	+1.09	192226	210038	unknown	unknown; similar to Hansenula wingei mitochondrial
YHR181W	__________	+1.11	565696	630483	unknown	unknown
YJL058C	__________	+1.03	168265	172492	unknown	unknown
YKL055C	OAR1______	-1.08	122729	113479	respiration	3-oxo-acyl-(acyl carrier protein) reductase
YLL057C	__________	-1.05	386559	368823	unknown	unknown; similar to C-terminal half E. coli dioxygenase
YLR362W	STE11_____	+1.00	144579	145143	signaling, pheromone and pseudohyphal growth pathways	MAPKKK (mitogen-activated protein kinase kinase kinase)
YMR097C	__________	+1.19	295703	350787	unknown	unknown
YNL149C	__________	+1.01	1247721	1260497	unknown	unknown
YOL055C	THI20_____	+1.00	234637	234837	thiamine metabolism (putative)	unknown; similar to bacterial transcription factors
YOR267C	__________	-1.01	886122	878888	unknown	protein kinase
YPL246C	__________	+1.02	416162	423617	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YBL067C	UBP13_____	-1.05	140651	133734	protein degradation, ubiquitin-mediated	ubiquitin carboxyl-terminal hydrolase
YDL069C	CBS1______	+1.12	199344	224110	protein synthesis	translation activator of COB mRNA (mitochondria)
YDR196C	__________	+1.10	330630	364748	unknown	unknown
YFL060C	SNO3______	+1.28	158745	202900	unknown	unknown; induced in stationary phase
YGL260W	__________	+1.01	118543	120080	unknown	unknown; similar to Yir040p
YHR011W	DIA4______	-1.04	192605	184963	pseudohyphal growth (putative)	unknown
YIL158W	__________	-1.13	794038	705193	unknown	unknown; similar to Ykr100p
YJR036C	HUL4______	-1.04	143804	138568	protein degradation (putative)	ubiquitin-protein ligase (E3)
YKR033C	__________	-1.04	116825	112024	unknown	unknown; similar to Gat1p
YLR190W	__________	-1.17	272063	233525	unknown	unknown
YML060W	OGG1______	-1.03	337526	328170	DNA repair	8-oxoguanine DNA glycosylase
YMR293C	__________	+1.03	171171	176673	unknown	unknown; similar to amidase
YNR012W	URK1______	-1.31	428927	326482	pyrimidine metabolism	uridine kinase
YOR091W	__________	-1.31	804803	616114	unknown	unknown
YPL067C	__________	+1.15	166325	192047	unknown	unknown
YBR139W	__________	+1.34	244004	325770	unknown	unknown; similar to serine-type carboxypeptidases
YCR076C	__________	+1.13	217434	244787	unknown	unknown
YDR011W	SNQ2______	-1.26	864927	687328	4-nitroquinoline-N-oxide resistance	putative ATP-dependent permease
YDR376W	ARH1______	+1.08	281985	303695	unknown	unknown; similar to human adrenodoxin reductase
YER073W	ALD5______	-1.15	537505	466496	fermentation	mitochondrial aldehyde dehydrogenase
YGL069C	__________	+1.01	546282	552597	unknown	unknown
YGR176W	__________	+1.03	383641	395386	unknown	unknown
YHR193C	EGD2______	+1.02	8376525	8508160	protein synthesis (putative)	homolog of human nascent-polypeptide-associated complex subunit
YJL070C	__________	-1.08	227066	209320	unknown	unknown; similar to rat AMP deaminase 1
YKL067W	YNK1______	+1.46	946759	1380599	nucleotide metabolism	nucleoside diphosphate kinase
YLR002C	__________	-1.24	920396	742115	unknown	unknown
YLR374C	__________	-1.01	132392	131558	unknown	unknown
YMR109W	MYO5______	-1.12	169157	151527	cytoskeleton	myosin, class I
YNL161W	CBK1______	-1.11	439094	394037	cell wall biosynthesis (putative)	protein kinase
YOL067C	RTG1______	-1.10	159829	145306	organelle communication	h-l-h transcription factor
YOR279C	__________	+1.08	273697	296499	unknown	unknown
YPL257W	__________	-1.00	151807	151409	unknown	unknown
YBL079W	NUP170____	-1.14	466234	409475	nuclear protein targeting	nuclear pore protein
YDL081C	RPP1A_____	+1.29	12273013	15864992	protein synthesis	ribosomal protein P1A, acidic
YDR208W	MSS4______	+1.03	359963	371442	actin organization	Phosphatidylinositol 4-Phosphate Kinase
YFR004W	RPN11_____	+1.07	789022	844171	transcription	putative global regulator
YGR009C	SEC9______	+1.09	413081	448862	secretion	plasma membrane t-SNARE
YHR022C	__________	-1.02	210467	205378	unknown	unknown; similar to N-terminal region of ras-related
YIL170W	HXT12_____	-1.19	221783	186431	transport	hexose permease
YJR048W	CYC1______	+1.01	2381909	2406467	oxidative phosphorylation	cytochrome-c isoform 1
YKR045C	__________	-1.00	882622	878265	unknown	unknown
YLR202C	__________	+1.10	172961	190682	unknown	unknown
YML072C	__________	-1.14	1694452	1490871	unknown	unknown
YMR304W	UBP15_____	-1.14	208135	182343	protein degradation, ubiquitin-mediated	putative deubiquitinating enzyme
YNR024W	__________	-1.09	356014	327380	unknown	unknown
YOR103C	OST2______	+1.14	788764	896586	protein glycosylation	oligosaccharyltransferase complex subunit
YPL079W	RPL21B____	+1.08	15309293	16466080	protein synthesis	ribosomal protein L21B
YPR170C	__________	-1.07	723657	673519	unknown	unknown
YBR151W	APD1______	+1.13	94552	106652	cytoskeleton (putative)	unknown
YCR088W	ABP1______	+1.21	583646	705798	cytoskeleton	actin binding protein
YDR023W	SES1______	-1.00	1787077	1779815	protein synthesis	tRNA synthetase, seryl
YDR388W	RVS167____	+1.11	463998	515191	cytoskeleton	actin-binding protein
YER085C	__________	-1.01	132781	131959	unknown	unknown
YGL081W	__________	+1.03	130331	134439	unknown	unknown
YGR188C	BUB1______	+1.05	266797	280320	cell cycle, checkpoint	protein kinase
YHR205W	SCH9______	+1.01	299384	301154	signaling	protein kinase
YJL082W	IML2______	+1.11	139873	155495	plasmid maintenance (putative)	unknown
YKL079W	SMY1______	+1.18	173473	204058	cytoskeleton	kinesin-related protein
YLR014C	PPR1______	+1.02	181849	185363	pyrimidine biosynthesis	transcription factor
YLR386W	__________	+1.15	161837	186474	unknown	unknown
YNL173C	MDG1______	-1.14	185669	162414	signaling, pheromone pathway	unknown
YOL079W	__________	-1.34	166771	124278	unknown	unknown; similar to NADH dehydrogenase chain 4-honeybee
YOR291W	__________	-1.20	657904	546512	unknown	unknown; similar to cation translocating ATPases
YPL267W	__________	-1.02	228511	223848	unknown	unknown
YBL091C	MAP2______	+1.06	573000	608889	protein processing	methionine aminopeptidase 2
YDL093W	PMT5______	-1.15	293267	255533	protein glycosylation	dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
YDR216W	ADR1______	+1.10	288186	316115	transcription	ADH2 and peroxisomal protein transcription factor
YFR016C	__________	+1.13	482696	547304	unknown	unknown; similar to Uso1p and to rat neurofilament
YGR021W	__________	-1.04	296708	285251	unknown	unknown
YHR034C	__________	-1.05	412793	393630	unknown	unknown
YIR004W	DJP1______	+1.01	424063	427943	peroxisome biogenesis	unknown
YJR060W	CBF1______	-1.10	192091	174880	mitosis	kinetochore protein
YKR057W	RPS21A____	+1.10	12917130	14167360	protein synthesis	ribosomal protein S21A
YLR214W	FRE1______	-1.52	1228881	809175	iron homeostasis	ferric (and cupric) reductase
YML084W	__________	-1.03	124558	121499	unknown	unknown
YMR314W	PRE5______	+1.04	1299503	1345826	protein degradation	20S proteasome subunit(alpha6)
YNR036C	__________	+1.02	769023	780783	unknown	unknown; similar to ribosomal protein S12
YOR115C	TRS33_____	+1.03	580716	595804	secretion (putative)	transport protein particle (TRAPP) subunit, 33 kD
YPL091W	GLR1______	-1.32	1077242	815742	glutathione metabolism	glutathione reductase
YPR182W	SMX3______	-1.08	379480	351669	mRNA splicing	core snRNP protein
YBR162W	YSY6______	+1.43	1385780	1982995	secretion (putative)	unknown
YCR099C	__________	+1.27	137292	174825	unknown	unknown; similar to Pep1p, probably represents a fragmented coding region of a pseudogene
YDR400W	URH1______	+1.14	211425	241953	pyrimidine metabolism	uridine nucleosidase
YER095W	RAD51_____	+1.22	249588	305604	DNA repair and recombination	recombinase
YGL093W	SPC105____	+1.08	234411	252045	cytoskeleton	spindle pole body component
YGR200C	ELP2______	-1.16	521680	450850	transcription	RNA polymerase II subunit (elongator)
YJL094C	__________	+1.03	150658	155866	unknown	unknown; similar to Enterococcus hirae Na+/H+-antiporter
YKL091C	__________	+1.22	206005	250434	unknown	unknown; similar to Sec14p
YLR026C	SED5______	+1.16	383249	443921	secretion	ER-to-Golgi t-SNARE
YLR398C	SKI2______	-1.08	153467	142070	mRNA decay and virus resistance	putative helicase
YMR132C	__________	-1.07	196256	183098	unknown	unknown
YNL185C	MRPL19____	-1.08	400829	371446	protein synthesis	ribosomal protein, mitochondrial L19
YOL091W	SPO21_____	-1.02	150179	147241	sporulation	unknown
YOR302W	__________	-1.09	117372	107450	unknown	unknown
YPL279C	__________	-1.36	517854	379887	unknown	unknown
YAL011W	__________	-1.39	204446	146706	unknown	unknown
YBR175W	__________	-1.30	259408	200106	unknown	unknown
YCRX05W	__________	-1.29	153576	118950
YDR046C	BAP3______	+1.08	276371	299047	transport	branched-chain amino acid permease
YDR413C	__________	-1.41	486217	345355	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YER108C	FLO8______	-1.33	216768	162540
YGL106W	MLC1______	-1.05	841596	798499	cytoskeleton	myosin light chain
YGR213C	RTA1______	+1.27	120947	153331	7-aminocholesterol resistance	unknown
YIL010W	DOT5______	+1.30	327181	425988	transcription	derepressor of telomeric silencing
YJL107C	__________	+1.02	117723	120580	unknown	unknown
YKL103C	LAP4______	+1.12	173557	194477	protein degradation	vacuolar aminopeptidase ysc1
YLR037C	__________	+1.25	157784	196740	unknown	unknown; similar to Pau3p and other members of the PAU1
YMR144W	__________	+1.02	214884	218244	unknown	unknown
YNL198C	__________	-1.13	106570	94162	unknown	unknown
YOR314W	__________	-1.05	110301	104703	unknown	unknown
YPR009W	__________	-1.16	367373	315630	unknown	unknown
YBL102W	SFT2______	-1.01	376416	371344	unknown	suppresses sed5 ts mutants
YCL009C	ILV6______	-1.63	583891	357867	isoleucine and valine biosynthesis	acetolactate synthase
YDL106C	GRF10_____	-1.22	167493	136827	phosphate signaling	transcription factor
YDR229W	__________	-1.13	126541	112235	unknown	unknown
YEL010W	__________	-1.12	95558	85699	unknown	unknown
YFR029W	PTR3______	-1.05	159180	151752	transport	peptide permease regulator
YGR032W	GSC2______	+1.54	163630	251769	cell wall biogenesis	1,3-beta-D-glucan synthase subunit
YHR046C	__________	+1.04	355252	369682	unknown	unknown; similar to inositol monophosphatase of E. coli,
YIR017C	MET28_____	+1.37	131672	180035	sulfur amino acid metbolism	transcriptional activator
YJR073C	OPI3______	+1.30	297904	388748	phospholipid metabolism	methylene-fatty-acyl-phospholipid synthase
YKR070W	__________	+1.19	369041	440193	unknown	unknown
YLR227C	__________	+1.27	220153	279197	unknown	unknown
YML096W	__________	-1.12	421492	376477	unknown	unknown
YNL010W	__________	+1.15	2420379	2794123	unknown	unknown
YNR049C	MSO1______	+1.20	467585	558895	secretion	unknown; interacts with Sec1p
YOR128C	ADE2______	-1.10	801702	730948	purine biosynthesis	phosphoribosylaminoimidazole carboxylase
YPL104W	MSD1______	-1.14	198784	174154	protein synthesis	tRNA synthetase, mitochondrial, aspartyl
YPR195C	__________	-1.05	129142	123233	unknown	unknown
YAL023C	PMT2______	-1.31	575953	438398	protein glycosylation	dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
YBR187W	__________	-1.53	484233	316933	unknown	unknown; similar to ND5 and PSB2 (SP:P03920 and SP:P20898)
YCRX17W	__________	-1.04	591955	568762
YDR058C	TGL2______	-1.05	137804	131043	fatty acid metabolism	triacylglycerol lipase
YDR425W	__________	-1.05	163708	155578	unknown	unknown
YGL118C	__________	+1.13	87581	98646	unknown	unknown; similar to Autographa californica late expression
YGR225W	AMA1______	+1.16	86019	99619	sporulation	activator of meiotic anaphase promoting complex
YIL021W	RPB3______	-1.09	753403	689743	transcription	RNA polymerase II 45 kDa subuni
YJL119C	__________	+1.18	138985	163454	unknown	unknown
YKL115C	__________	+1.10	112125	123128	unknown	unknown
YLR049C	__________	+1.16	322896	373505	unknown	unknown
YLR421C	RPN13_____	+1.03	1008530	1037702	protein degradation (putative)	26S proteasome subunit (putative)
YMR155W	__________	-1.06	217899	205362	unknown	unknown; similar to E. coli ribosomal protein S8
YNL210W	MER1______	+1.03	127144	131143	meiosis, MER2 mRNA splicing	RNA binding protein
YOL114C	__________	+1.07	132261	141149	unknown	unknown; similar to human DS-1 protein
YOR326W	MYO2______	-1.06	130297	123012	cytoskeleton	myosin, class V
YPR021C	__________	+1.06	268346	284068	unknown	unknown; similar to proteins of the mitochondrial carrier family
YBR001C	NTH2______	-1.18	203651	171977	trehalose metabolism	alpha,alpha-trehalase
YCL022C	__________	-1.54	306235	198236	unknown	unknown
YDL118W	__________	-1.24	194424	157002	unknown	unknown
YEL021W	URA3______	+1.19	15842660	18861801	pyrimidine biosynthesis	orotidine-5'-phosphate decarboxylase
YFR038W	__________	-1.28	675922	528165	unknown	unknown
YGR039W	__________	+1.01	194295	197092	unknown	unknown; similar to Sauroleishmania tar protein 1
YIR026C	YVH1______	-1.32	563517	427686	sporulation	protein phosphatase
YJR086W	STE18_____	+1.31	548204	716934	signaling, pheromone pathway	gamma subunit of G protein
YKR082W	NUP133____	-1.10	529454	481978	nuclear protein targeting	nuclear pore protein
YLR237W	THI7______	-1.03	192649	186888	transport	thiamine transporter
YML106W	URA5______	-1.07	3474903	3240621	pyrimidine biosynthesis	orotate phosphoribosyltransferase
YNL022C	__________	-1.24	461586	372470	unknown	unknown
YNR061C	__________	-1.14	841449	736578	unknown	unknown
YOR140W	SFL1______	-1.14	226450	198994	cell surface assembly	transcription factor
YPL116W	HOS3______	-1.14	205481	181030	unknown	unknown; similar to Hda1p, Rpd3p, Hos2p, and Hos1p
YAL034W	MTW1______	-1.19	224163	189103	unknown	unknown
YBR199W	KTR4______	-1.21	308841	256059	protein glycosylation	putative alpha-1,2-mannosyltransferase
YDR070C	__________	-1.25	156041	125274	unknown	unknown
YDR437W	__________	-1.09	209191	192365	unknown	unknown
YER131W	RPS26B____	+1.15	15468824	17865122	protein synthesis	ribosomal protein S26B
YGL130W	CEG1______	-1.09	224018	204805	mRNA capping	mRNA guanylyltransferase
YGR237C	__________	+1.10	213145	234337	unknown	unknown
YIL033C	SRA1______	-1.03	505476	488445	signaling?	cAMP dependent protein kinase, regulatory subunit
YJL131C	__________	+1.09	235514	256352	unknown	unknown; similar to carbamylphosphate synthetase
YKL127W	PGM1______	-1.13	438269	389306	glycolysis	phosphoglucomutase
YLR061W	RPL22A____	-1.02	8613328	8453294	protein synthesis	ribosomal protein L22A
YLR431C	__________	-1.07	204833	191899	unknown	unknown
YNL222W	SSU72_____	-1.11	147931	132884	transcription	nuclear protein
YOL126C	MDH2______	+1.13	431381	486742	TCA cycle	malate dehydrogenase
YOR338W	__________	+1.03	166259	170806	unknown	unknown
YPR033C	HTS1______	-1.16	1869978	1616973	protein synthesis	tRNA synthetase, histidyl
YBR012W	TY1A______	-1.07	3075992	2872733	unknown	unknown
YCL034W	__________	+1.02	546584	556627	unknown	unknown
YDL130W	RPP1B_____	-1.06	12822783	12095478	protein synthesis	ribosomal protein L44', acidic
YDR253C	MET32_____	+1.07	384558	412586	methionine metabolism	transcription factor
YEL033W	__________	+1.11	5379762	5947977	unknown	unknown
YFR050C	PRE4______	+1.26	1151452	1454507	protein degradation	proteasome subunit, B type
YGR051C	__________	+1.22	241692	294125	unknown	unknown
YHR067W	__________	-1.07	200960	188220	unknown	unknown
YIR038C	GTT1______	+1.00	381078	382151	glutathione metabolism	glutathione transferase
YJR097W	__________	+1.04	217051	225406	unknown	unknown; similar to E. coli DnaJ
YKR094C	RPL40B____	+1.07	14574986	15617777	protein synthesis	ribosomal protein L40B
YLR249W	YEF3______	+1.09	157594	171550	protein synthesis	translation elongation factor eEF3
YML117W	__________	-1.07	165320	154667	unknown	unknown
YNL034W	__________	-1.15	140216	122319	unknown	unknown; similar to Ynl018p
YNR073C	__________	-1.18	155610	132053	unknown	unknown; similar to E. coli D-mannonate oxidoreductase
YOR150W	MRPL23____	+1.07	490206	523191	protein synthesis	ribosomal protein, mitochondrial large subunit
YPL128C	TBF1______	-1.12	319035	283877	telomere length regulation	telomere TTAGGG repeat-binding factor
YAL043C	PTA1______	-1.08	141728	131083	tRNA processing	unknown
YBR211C	AME1______	+1.03	218419	224913	unknown	microtubule associated
YDR082W	STN1______	+1.03	196095	202581	telomere length regulation	asssociates with Cdc13p
YDR449C	__________	-1.09	492465	451888	unknown	unknown
YER141W	COX15_____	-1.14	312408	274298	respiration	cytochrome oxidase assembly factor
YGL142C	GPI10_____	+1.02	160304	164167	phospholipid metabolism	glycosyl phosphatidyl inositol (GPI) synthesis

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YGR249W	MGA1______	+1.05	112398	117752	pseudohyphal growth (putative)	unknown
YIL045W	PIG2______	-1.01	199733	197691	glucose repression	(putative) Glc7p regulatory subunit
YJL143W	TIM17_____	-1.15	965791	842146	mitochondrial protein targeting	inner membrane translocase component
YKL139W	CTK1______	+1.09	193823	210871	transcription	protein kinase; phosphorylates RNA pol. II subunit
YLR073C	__________	-1.05	606794	577176	unknown	unknown
YLR443W	ECM7______	+1.17	270715	315728	cell wall biogenesis	unknown
YMR176W	ECM5______	+1.05	358343	377756	cell wall biogenesis	unknown
YNL234W	__________	-1.01	190796	189633	unknown	unknown; similar to mammalian globins
YOL138C	__________	-1.11	318665	288197	unknown	unknown
YOR348C	PUT4______	-1.02	139434	136923	transport	proline and gamma-aminobutyrate permease
YPR045C	__________	+1.10	198001	217967	unknown	unknown; similar to C. elegans protein
YBR023C	CHS3______	+1.20	139690	167599	cell wall biogenesis	chitin synthase III
YCL046W	__________	+1.08	86489	93534	unknown	unknown
YDL140C	RPO21_____	-1.23	660385	535524	transcription	RNA polymerase II 215 kD subunit
YEL045C	__________	+1.00	107672	107757	unknown	unknown
YGR063C	SPT4______	+1.27	507579	645665	transcription	elongation factor
YHR078W	__________	-1.11	214090	193181	unknown	unknown
YJR109C	CPA2______	-1.10	142879	130415	glutamate metabolism	carbamyl phosphate synthetase
YKR106W	__________	-1.06	142429	134466	unknown	major facilitator superfamily
YLR258W	GSY2______	+1.13	153548	173089	glycogen metabolism	glycogen synthase
YML129C	COX14_____	+1.09	324589	352720	respiration	cytochrome-c oxidase assembly protein
YNL044W	YIP3______	+1.16	1171527	1362992	unknown	unknown; interacts with Ypt protein(s)
YOR162C	YRR1______	-1.06	317555	299138	transport	transcriptional activator of SNQ2
YPL140C	MKK2______	-1.11	228649	205188	signaling, PKC1 pathway	MAP kinase (mitogen-activated protein kinase)
YAL056W	__________	+1.11	83774	93015	unknown	unknown
YBR223C	__________	+1.15	95648	110442	unknown	unknown
YDR094W	__________	+1.17	419651	492262	unknown	unknown
YDR461W	MFA1______	+1.09	111465	121600	mating	a-factor precursor
YER151C	UBP3______	+1.02	232081	236697	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YGL154C	LYS5______	+1.12	248922	279202	lysine biosynthesis	aminoadipate-semialdehyde dehydrogenase subunit
YGR261C	APL6______	+1.05	278749	293925	vacuolar protein targeting	AP-3 complex subunit
YIL057C	__________	-1.02	1236766	1217383	unknown	unknown
YJL155C	FBP26_____	+1.38	169286	233709	fructose metabolism	fructose-2,6-bisphosphatase
YKL151C	__________	+1.11	229526	255480	unknown	unknown
YLR085C	ARP6______	-1.01	183623	181474	cytoskeleton (putative)	actin-related protein
YLR455W	__________	-1.19	221251	186450	unknown	unknown
YMR188C	__________	+1.02	441407	450255	unknown	unknown; similar to 30S ribosomal proteins (S17)
YNL246W	__________	-1.05	530325	506554	unknown	unknown; similar to Drosophila melanogaster SET protein
YOL150C	__________	+1.15	586950	673194	unknown	unknown
YOR360C	PDE2______	-1.03	553876	540038	signaling (putative)	high affinity 3',5'-cAMP phosphodiesterase
YPR057W	BRR1______	+1.06	334517	353572	mRNA splicing	required for snRNP biogenesis
YBR035C	PDX3______	+1.29	491803	633352	sterol uptake (putative)	pyridoxine (pyridoxamine) phosphate oxidase
YCL058C	__________	+1.01	602446	608985	unknown	unknown
YDL152W	__________	-1.10	108266	98816	unknown	unknown
YDR273W	__________	+1.14	144788	165714	unknown	unknown
YEL057C	__________	+1.21	152393	183969	unknown	unknown
YGR075C	PRP38_____	+1.13	375845	424139	mRNA splicing	U4/U6 snRNA dissociation factor
YHR089C	GAR1______	-1.25	2039224	1627354	rRNA processing	snoRNP protein
YJR121W	ATP2______	-1.08	1524902	1409886	ATP synthesis	F1F0-ATPase complex, F1 beta subunit
YLR269C	__________	+1.01	218043	220716	unknown	unknown
YMR008C	PLB1______	+1.10	268999	295857	phospholipid metabolism	phospholipase B
YOR174W	MED4______	+1.08	116185	125479	transcription	RNA polymerase II mediator subunit
YPL152W	RRD2______	-1.01	271863	269932	drug resistance	unknown
YBR235W	__________	+1.06	123937	131514	unknown	unknown; similar to human SLC12A1 gene for which mutations
YDR104C	SPO71_____	+1.06	137552	145275	sporulation	unknown
YDR473C	PRP3______	+1.01	229595	231150	mRNA splicing	U4/U6 snRNP protein
YER161C	SPT2______	+1.05	482713	506712	chromatin structure	HMG-like non-histone protein
YGL166W	CUP2______	+1.19	297267	352370	transcription	copper-dependent transcriptional activator
YGR273C	__________	+1.01	164744	166257	unknown	unknown
YIL068C	SEC6______	-1.23	653890	529943	secretion	exocyst complex subunit
YJL167W	ERG20_____	+1.22	4191400	5122376	sterol metabolism	farnesyl-pyrophosphate synthetase
YKL163W	PIR3______	+1.03	2258919	2319253	unknown	unknown; similar to members of the Pir1p/Hsp150p/Pir3p
YLR097C	__________	+1.12	277691	311616	unknown	unknown
YLR467W	YRF1-5____	+1.02	1626770	1659629	unknown	Y' helicase (subtelomerically-encoded)
YMR199W	CLN1______	+1.15	269043	308807	cell cycle	G1/S cyclin
YNL258C	__________	+1.11	123236	136261	unknown	unknown
YOL162W	__________	+1.15	135699	156682	unknown	unknown
YOR372C	NDD1______	-1.22	671112	548845	mitosis (putative)	unknown
YPR069C	SPE3______	+1.07	114869	123189	polyamine biosynthesis	putrescine aminopropyltransferase (spermidine synthase)
YBR047W	__________	+1.08	95278	103149	unknown	unknown
YCL073C	__________	+1.11	127425	141061	unknown	major facilitator superfamily
YDL164C	CDC9______	-1.16	325077	281167	DNA replication and repair	DNA ligase
YDR285W	ZIP1______	-1.06	141072	133323	meiosis	synaptonemal complex protein
YEL068C	__________	+1.03	196969	202118	unknown	unknown
YGR087C	PDC6______	-1.97	3290656	1668565	glycolysis	pyruvate decarboxylase 3
YHR101C	BIG1______	-1.09	232614	213986	signaling (putative)	suppresses rot1/rot2 synthetic lethality
YJR133W	XPT1______	-1.06	667453	632553	xanthine utilization	xanthine phosphoribosyltransferase
YLR281C	__________	+1.05	111334	117258	unknown	unknown
YMR020W	FMS1______	+1.11	246003	272241	sterol metabolism (putative)	unknown
YNL066W	SUN4______	-1.21	1456065	1204821	aging	unknown
YOR186W	__________	-1.09	137922	126990	unknown	unknown
YPL164C	MLH3______	-1.07	227211	212666	DNA repair; DNA recombination	MutL homolog
YAR020C	PAU7______	+1.03	121647	125464	unknown	unknown; similar to Pau3p/Ycr104p, PAU1 family
YBR247C	ENP1______	-1.31	754431	574355	protein glycosylation	putative oligosaccharyltransferase complex subunit
YDR116C	__________	-1.03	260299	251544	unknown	unknown; similar to prokaryotic ribosomal protein L1
YDR485C	__________	+1.11	150622	167751	unknown	unknown; similar to human YL-1 protein, GB:D43642
YER172C	BRR2______	-1.06	237217	224730	mRNA splicing	RNA helicase
YGL178W	MPT5______	+1.07	117372	125869	unknown	unknown
YGR285C	ZUO1______	-1.07	5628955	5285246	unknown	binds Z-DNA
YIL078W	THS1______	-1.27	2101605	1650758	protein synthesis	tRNA synthetase, threonyl
YJL179W	PFD1______	+1.12	548481	615561	protein folding	prefoldin subunit 1
YKL175W	__________	-1.10	554016	505183	unknown	unknown
YLR109W	AHP1______	-1.18	7717478	6531760	oxidative stress response	alkyl hydroperoxide reductase
YMR211W	__________	-1.08	258129	239215	unknown	unknown; similar to beta-tubulins
YNL270C	ALP1______	-1.12	155487	138745	transport	basic amino acid permease
YOR008C	SLG1______	-1.08	136488	125974	signaling, stress response and cell wall integrity	unknown
YOR384W	FRE5______	-1.08	148186	137776	unknown	unknown; similar to Fre2p
YPR081C	__________	-1.09	227310	208596	unknown	unknown; similar to glycyl-tRNA synthetases
YBR059C	AKL1______	-1.12	253302	226526	unknown	protein kinase
YCLX09W	__________	-1.04	107165	103208

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDL176W	__________	+1.11	207474	229825	unknown	unknown
YDR297W	SUR2______	+1.14	631593	718691	sphingolipid metabolism	hydroxylase
YER002W	__________	+1.18	99688	117168	unknown	unknown
YGR099W	TEL2______	+1.08	222547	240913	telomere length regulation	telomere binding protein
YHR113W	__________	-1.23	756247	614032	unknown	unknown; similar to vacuolar aminopeptidase Lap4p/Ape1p
YJR145C	RPS4A_____	+1.34	14017090	18851846	protein synthesis	ribosomal protein S4A
YLR292C	SEC72_____	+1.13	945251	1070813	secretion	ER protein translocation subcomplex subunit
YNL078W	__________	+1.04	343048	356983	unknown	unknown
YOR196C	LIP5______	-1.18	712698	605209	fatty acid metabolism	lipoic acid synthase
YPL176C	__________	-1.00	157607	157143	unknown	unknown; similar to Ssp134p
YAR043C	__________	-1.05	98675	94309
YBR259W	__________	+1.21	122691	148111	unknown	unknown; similar to serine-type carboxypeptidase Prc1p
YDR128W	__________	+1.01	167052	167905	unknown	unknown
YDR497C	ITR1______	+1.03	1110912	1141143	transport	inositol permease
YER183C	__________	+1.18	115099	136248	unknown	unknown
YGL190C	CDC55_____	+1.04	243108	252070	cell cycle	protein phosphatase
YIL089W	__________	+1.06	156020	164933	unknown	unknown
YJL191W	RPS14B____	-1.23	4254102	3448412	protein synthesis	ribosomal protein S14B
YKL187C	__________	+1.03	153058	158067	unknown	unknown; similar to 4-mycarosyl isovaleryl-CoA transferase
YLR121C	YPS3______	+2.10	250449	524860	protein processing	GPI-anchored aspartic protease
YMR223W	UBP8______	-1.28	228193	177986	protein degradation, ubiquitin-mediated	putative deubiquitinating enzyme
YNL282W	POP3______	-1.33	171800	128890	rRNA and tRNA processing	RNase P and RNase MRP subunit
YOR020C	HSP10_____	+1.05	1614605	1694231	protein folding	mitochondrial chaperonin
YPR093C	__________	-1.10	269243	244664	unknown	unknown
YBR071W	__________	+1.52	300620	457416	unknown	unknown; similar to Herpesvirus saimiri EERF2
YCR009C	RVS161____	+1.23	91712	113002	cytoskeleton	actin-binding protein
YDL188C	PPH22_____	+1.16	959810	1109578	cell cycle	protein phosphatase 2A
YDR309C	GIC2______	+1.32	234595	309395	bud emergence	binds Cdc42p
YER012W	PRE1______	+1.17	985859	1149417	protein degradation	20S proteasome subunit C11(beta4)
YHR125W	__________	+1.04	115296	119410	unknown	unknown
YJR157W	__________	+1.05	104608	109752	unknown	unknown
YLR304C	ACO1______	+1.05	552072	577943	TCA cycle	aconitase
YMR043W	MCM1______	-1.18	2674441	2273828	transcription	multifunctional regulator
YNL090W	RHO2______	-1.01	450977	446942	signaling	GTP-binding protein, rho family
YOR208W	PTP2______	+1.06	246809	262657	signaling, high osmolarity pathway	protein tyrosine phosphatase
YPL187W	MF(ALPHA)1	-1.32	14168037	10719005	mating	alpha factor precursor
YBL008W	HIR1______	-1.15	92509	80110	transcription	histone transcription inhibitor
YBR271W	__________	-1.56	317920	203556	unknown	unknown; similar to Clostridium botulinum C1 toxin
YDL010W	__________	-1.08	256444	237796	unknown	unknown; similar to Ybr014p and glutaredoxins
YDR140W	__________	-1.04	378229	363977	unknown	unknown
YDR509W	__________	-1.20	110872	92069	unknown	unknown
YFL008W	SMC1______	-1.28	685096	535123	mitosis, chromosome condensation and segregation	unknown
YGL202W	ARO8______	-1.18	1079163	910855	aromatic amino acid biosynthesis	aromatic amino acid aminotransferase
YHL008C	__________	+1.06	160039	169173	unknown	unknown; similar to E. coli NirC potential formate
YIL100W	__________	+1.05	114998	120210	unknown	unknown
YJL203W	PRP21_____	+1.08	223257	240475	mRNA splicing	U2 snRNP activation
YKL199C	YKT9______	+1.19	216490	256651	unknown	unknown
YLR133W	CKI1______	-1.11	141785	127165	lipid metabolism	choline kinase
YMR235C	RNA1______	-1.13	1927638	1705020	RNA export	GTPase activating protein for Gsp1p
YNL292W	PUS4______	-1.27	434986	343225	tRNA processing	pseudouridine synthase
YOR032C	HMS1______	+1.09	149188	162009	pseudohyphal growth	similar to myc family of transcription factors
YPL010W	RET3______	+1.21	1625258	1962042	secretion	vesicle coat component
YPR105C	__________	-1.00	516983	515055	unknown	unknown
YBR083W	TEC1______	-1.31	264523	202642	pseudohyphal growth	trancriptional activator
YCR020C	PET18_____	-1.02	138508	135450	mitochondrial DNA maintenance	unknown
YDL200C	MGT1______	+1.10	155191	170282	DNA repair	6-O-methylguanine-DNA methylase
YDR319C	__________	-1.02	196425	192278	unknown	unknown
YER022W	SRB4______	-1.20	219994	184078	transcription	RNA polymerase II mediator subunit
YGL010W	__________	-1.14	146883	128926	unknown	unknown
YGR121C	MEP1______	+1.14	186917	212822	transport	ammonia permease
YHR136C	SPL2______	+2.24	145908	326151	cell cycle	protein kinase inhibitor
YJL010C	__________	-1.26	425835	337362	unknown	unknown
YKL009W	MRT4______	-1.13	1994336	1771224	mRNA decay	unknown
YLL010C	PSR1______	-1.03	341315	332336	salt tolerance (putative)	phosphatase
YLR315W	__________	+1.12	102778	115372	unknown	unknown
YNL102W	POL1______	-1.01	487500	481996	DNA replication	polymerase alpha 180 kD subunit
YOL010W	RCL1______	-1.08	538938	496863	unknown	putative RNA 3'-terminal phosphate cyclase
YOR220W	__________	+1.33	312056	414778	unknown	unknown
YPL199C	__________	+1.06	1162763	1228632	unknown	unknown
YAR069C	__________	+1.03	121280	125258	unknown	unknown
YBL020W	RFT1______	-1.33	242229	182101	cell cycle	unknown
YBR283C	SSH1______	-1.50	1202100	803863	secretion	ER protein translocation complex subunit
YDL022W	GPD1______	+1.04	560753	585925	glycerol metabolism	glycerol-3-phosphate dehydrogenas
YDR152W	__________	-1.19	846393	709085	unknown	unknown
YDR521W	__________	-1.17	141261	120306	unknown	unknown
YFL017C	GNA1______	-1.00	494126	494040	UDP-N-acetylglucosamine biosynthesis	glucosamine-phosphate N-acetyltransferase
YGL214W	__________	+1.08	112239	120891	unknown	unknown
YHL018W	__________	+1.14	90431	103320	unknown	unknown; similar to human pterin-4-alpha-carbinolamine
YIL112W	__________	+1.04	225438	233624	unknown	unknown; similar to ankyrin and coiled-coil proteins
YJL215C	__________	+1.13	105285	119011	unknown	unknown
YKL211C	TRP3______	-1.05	428224	406176	tryptophan biosynthesis	anthranilate synthase component II and indole-3-phosphate synthase
YLR145W	__________	+1.11	219327	244147	unknown	unknown
YML019W	OST6______	-1.01	524796	519476	protein glycosylation	putative N-oligosaccharyltransferase complex subunit
YMR246W	FAA4______	-1.69	1439854	849808	fatty acid metabolism	long-chain-fatty-acid--CoA ligase
YNL304W	YPT11_____	-1.02	209165	204131	signaling (putative)	unknown; similar to Ypt1p and many other ras-like GTPases
YOR044W	__________	+1.03	162555	167112	unknown	unknown
YPL022W	RAD1______	-1.17	478101	409253	DNA repair, nucleotide excision	repairosome component
YPR117W	__________	-1.02	117163	115304	unknown	unknown
YBR093C	PHO5______	+1.87	984161	1838472	phosphate metabolism	acid phosphatase, repressible
YCR030C	__________	-1.12	161560	144138	unknown	unknown
YDL212W	SHR3______	-1.02	576786	568234	secretion; protein targeting, plasma membrane	ER membrane protein
YDR331W	GPI8______	-1.20	243851	203904	protein processing	transamidase (putative), GPI anchor attachment
YER034W	__________	-1.11	167262	150207	unknown	unknown
YGL022W	STT3______	-1.49	465378	312436	protein glycosylation	oligosaccharyltransferase complex assembly
YGR133W	PEX4______	+1.01	193316	194469	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YHR146W	__________	-1.53	896324	584529	unknown	unknown; similar to pheromone adaptation protein Mdg1p
YJL022W	__________	+1.03	124918	128324	unknown	unknown
YKL021C	MAK11_____	-1.27	627078	494747	dsRNA virus propagation	unknown; essential gene
YLL022C	HIF1______	-1.15	580321	502925	chromatin structure	interacts with histone acetyltransferase
YLR327C	__________	+2.88	116244	335214	unknown	unknown; similar to Stf2p

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YMR064W	AEP1______	-1.11	334126	300975	protein synthesis(putative)	ATP9/OLI1 expression
YNL114C	__________	-1.23	886372	720100	unknown	unknown
YOL022C	__________	-1.13	931769	824055	unknown	unknown
YOR232W	MGE1______	-1.09	1893376	1730281	mitochondrial protein targeting	could change to: protein folding; mitochondrial chaperone (has a targeting phenotype, only b/c misfolded proteins accumulate in the mito., which backs the pathway up)
YPL211W	NIP7______	-1.18	2302288	1950302	rRNA processing	unknown
YBL032W	__________	-1.30	627471	484036	unknown	unknown
YBR295W	PCA1______	-1.07	116461	108391	transport	Cu(2+) ATPase
YDL034W	__________	-1.04	110871	106712	unknown	unknown
YDR164C	SEC1______	-1.20	230168	191237	secretion	SNARE docking complex subunit (putative0
YDR533C	__________	+1.14	206105	235307	unknown	unknown
YFL027C	__________	-1.23	196790	160564	unknown	unknown
YHL030W	ECM29_____	+1.08	97216	104968	cell wall biogenesis	unknown
YIL124W	AYR1______	+1.20	518087	622129	lipid metabolism	1-Acyl dihydroxyacetone phosphate reductase
YJR003C	__________	-1.16	403916	349442	unknown	unknown; similar to human collagen alpha 3 (VI) chain
YKL223W	__________	+1.02	110575	112615	unknown	unknown
YLR157C	ASP3-2____	+1.06	131659	139497	asparagine utilization	L-asparaginase II
YMR259C	__________	-1.22	580515	475368	unknown	unknown
YNL316C	PHA2______	-1.05	219373	209722	phenylalanine biosynthesis	prephenate dehydratase
YOR056C	__________	-1.34	896600	671166	unknown	unknown
YPL034W	__________	+1.14	262488	298529	unknown	unknown
YPR129W	SCD6______	-1.12	656960	588636	secretion (putative)	suppressor of clathrin deficiency
YBR105C	VID24_____	+1.29	270737	348761	vacuolar protein targeting	peripheral vesicle membrane protein
YCR042C	TSM1______	-1.06	157831	148571	transcription	TFIID associated factor (TAF)
YDL224C	WHI4______	-1.07	208354	195415	cell size	putative RNA binding protein
YDR343C	HXT6______	-1.02	2051507	2005475	transport	hexose permease
YER044C	__________	+1.11	638826	710405	unknown	unknown
YGL034C	__________	-1.14	117257	103132	unknown	unknown
YGR145W	__________	-1.26	686582	544156	unknown	unknown; similar to MESA gene of Plasmodium falciparum
YHR158C	KEL1______	-1.10	166535	151315	unknown	null mutant has mating defect
YJL034W	KAR2______	-1.19	3159012	2658088	secretion	BiP homolog; ER protein translocation
YKL033W	__________	-1.10	168461	153315	unknown	unknown
YLL034C	__________	-1.24	289273	232866	unknown	unknown; similar to mammalian valosin-containing protein
YLR339C	__________	-2.23	2921774	1307583	unknown	unknown
YNL126W	SPC98_____	-1.05	174904	166796	cytoskeleton	spindle pole body component
YOL034W	__________	-1.00	210601	210194	unknown	unknown
YOR244W	ESA1______	+1.01	290571	294076	chromatin structure	histone acetyltransferase complex subunit
YPL223C	GRE1______	-1.10	163421	148884	unknown	unknown; induced by osmotic stress
YBL044W	__________	-1.02	109880	107671	unknown	unknown
YDL046W	__________	-1.01	388483	386312	unknown	unknown
YDR174W	HMO1______	+1.01	1492312	1511909	chromatin structure	non-histone protein
YDR545W	YRF1-1____	+1.18	953164	1123972	unknown	Y' helicase (subtelomerically-encoded)
YFL037W	TUB2______	-1.05	895175	852702	cytoskeleton	beta-tubulin
YGL237C	HAP2______	-1.14	972470	851877	transcription; respiration	transcription factor, activator of CYC1
YHL041W	__________	-1.07	133397	124393	unknown	unknown
YIL136W	OM45______	+1.21	287371	348646	(putative) mitochondrial organization	outer mitochondrial membrane protein
YJR014W	__________	-1.21	904100	745744	unknown	unknown
YKR010C	TOF2______	-1.07	233532	217554	DNA replication (putative)	interacts with DNA
YLR167W	RPS31_____	+1.21	15849454	19118644	protein synthesis	ribosomal protein S31
YML040W	__________	-1.19	3087017	2602603	unknown	unknown
YMR271C	URA10_____	-1.02	193892	190931	pyrimidine biosynthesis	orotate phosphoribosyltransferase
YNL328C	MDJ2______	-1.04	124773	119945	protein folding	mitochondrial chaperonin
YOR068C	__________	-1.21	150193	123999	unknown	unknown
YPL046C	ELC1______	-1.17	984830	842218	transcription	elongation factor Elongin C
YPR139C	__________	-1.05	488539	466735	unknown	unknown
YBR116C	__________	+1.04	107939	112525	unknown	unknown; similar to sea urchin NADH chain ND2
YCR054C	CTR86_____	-1.09	128744	117653	unknown	unknown
YDL236W	PHO13_____	-1.05	757728	723101	unknown	protein phosphatase and 4-nitrophenylphosphatase
YDR355C	__________	-1.11	107064	96296	unknown	unknown
YER055C	HIS1______	-1.04	2261345	2182219	histidine biosynthesis	ATP phosphoribosyltransferase
YGL046W	__________	-1.15	150624	131452	unknown	unknown
YGR157W	CHO2______	+1.10	351554	386909	phospholipid metabolism	phosphatidylethanolamine N-methyltransferase
YHR170W	NMD3______	-1.32	715964	543490	mRNA decay, nonsense-mediated	Nam7p/Upf1p-interacting protein
YJL047C	RTT101____	-1.07	180127	169069	transposition (putative)	unknown; regulator of Ty1 transposition
YKL044W	__________	-1.05	130104	124403	unknown	unknown
YLL046C	RNP1______	-1.04	102126	98496	unknown	ribonucleoprotein
YLR351C	NIT3______	+1.10	747684	825340	unknown	nitrilase
YNL138W	SRV2______	-1.13	1131563	1000961	signaling	adenylate cyclase-associated protein
YOL046C	__________	-1.07	140902	131375	unknown	unknown
YOR256C	__________	-1.06	243284	229798	unknown	unknown; similar to secretory protein Ssp134p
YPL235W	RVB2______	-1.23	1296173	1052665	unknown	unknown; similar to RUVB
YBL056W	PTC3______	-1.09	646708	595298	osmotic stress response (putative)	protein phosphatase
YDL058W	USO1______	-1.22	580404	474873	secretion	SNARE docking complex assembly
YDR185C	__________	+1.01	165191	166652	unknown	unknown; similar to Msf1p
YFL049W	__________	-1.04	199025	190851	unknown	unknown; similar to Npl6p
YGL249W	ZIP2______	-1.16	174474	149813	meiosis, synapsis	unknown
YIL148W	RPL40A____	+1.18	15810248	18710744	protein synthesis	ribosomal protein L40A
YKR022C	__________	-1.02	462117	455043	unknown	unknown
YLR179C	__________	+1.50	587216	881099	unknown	unknown; similar to Tfs1p
YML050W	__________	+1.14	193334	220105	unknown	unknown; similar to potato sucrose cleavage protein
YMR283C	RIT1______	-1.12	210478	187985	tRNA processing	initiator methionine tRNA 2'-O-ribosyl phosphate transferase
YNR001C	CIT1______	+1.46	281267	410386	TCA cycle	citrate synthase
YOR080W	DIA2______	+1.08	214045	230305	pseudohyphal growth (putative)	unknown
YPL058C	PDR12_____	+1.02	173258	177387	drug resistance	transporter
YPR151C	__________	+1.15	152204	174705	unknown	unknown
YBR128C	APG14_____	+1.08	140999	152489	autophagy	unknown; interacts with Apg6p/Vps30p
YCR066W	RAD18_____	-1.00	175281	174884	DNA repair, postreplication	forms complex with Rad6p; putative ATPase
YDL248W	COS7______	+1.65	1015598	1675464	unknown	unknown; similar to other subtelomerically-encoded
YER065C	ICL1______	-1.07	166793	156064	glyoxylate cycle	isocitrate lyase
YGL058W	RAD6______	+1.05	593430	620304	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YGR165W	__________	-1.03	405358	394955	unknown	unknown
YHR182W	__________	-1.10	261180	238478	unknown	unknown
YJL059W	YHC3______	-1.01	286174	282432	unknown	unknown; similar to human Batten disease-related protein
YKL056C	__________	+1.03	8549004	8797112	unknown	unknown
YLL058W	__________	-1.11	1907018	1725712	unknown	unknown; similar to Neurospora crassa O-succinylhomoserine
YLR363C	NMD4______	-1.08	202193	187422	unknown	Nam7p/Upf1p-interacting protein
YMR098C	__________	-1.07	268885	251820	unknown	unknown
YNL150W	__________	-1.00	1542538	1538453	unknown	unknown
YOL056W	GPM3______	-1.14	453852	399189	glycolysis	phosphoglycerate mutase
YOR268C	__________	-1.08	123354	114305	unknown	unknown
YPL247C	__________	-1.09	151996	140043	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YBL068W	PRS4______	-1.01	328024	324856	pentose phosphate cycle	ribose-phosphate pyrophosphokinase
YDL070W	BDF2______	+1.16	633659	732491	unknown	unknown; similar to mammalian glycogen
YDR197W	CBS2______	+1.11	220609	244330	protein synthesis	translation activator of COB mRNA
YFL061W	__________	-1.06	166723	157515	unknown	unknown; similar to E. coli cyanamide hydratase (urea
YGL261C	__________	+1.15	311077	357882	unknown	unknown; similar to Pau1p and members of the PAU1
YHR012W	VPS29_____	+1.10	499370	547585	vacuolar protein targeting	targets vacuolar receptor, Vps10
YIL159W	BNR1______	+1.00	1036771	1040519	cytoskeleton	actin filament organization
YJR037W	__________	-1.00	120324	119936	unknown	unknown
YKR034W	DAL80_____	+1.02	103460	105153	nitrogen catabolism	transcription factor
YLR191W	PEX13_____	-1.11	290854	263010	peroxisomal protein targeting	docks peroxisomal protein receptor
YML061C	PIF1______	-1.03	148513	144552	DNA repair, mitochondrial	DNA helicase
YMR294W	JNM1______	-1.02	321254	315606	mitosis, nuclear migration	unknown
YNR013C	__________	+1.04	839920	876394	unknown	unknown; major facilitator superfamily
YOR092W	ECM3______	-1.09	268402	246977	cell wall biogenesis	unknown
YPL068C	__________	-1.00	307056	305631	unknown	unknown
YPR159W	KRE6______	+1.16	364324	423385	cell wall biogenesis	glucan synthase subunit
YBR140C	IRA1______	-1.13	159191	140500	signaling, Ras pathway	GTPase-activating protein for Ras1p and Ras2p
YCR077C	PAT1______	-1.23	515481	419364	mitosis; chromosome transmission	topoisomerase II
YDR012W	RPL4B_____	-1.41	9780600	6935231	protein synthesis	ribosomal protein L4B
YDR377W	ATP17_____	+1.38	600272	830692	ATP synthesis	ATP synthase subunit f
YER074W	RPS24A____	+1.07	10680696	11404224	protein synthesis	ribosomal protein S24A
YGL070C	RPB9______	-1.00	524698	524184	transcription	RNA polymerase II 14.2 subunit
YGR177C	ATF2______	-1.36	263894	193942	acetate ester biosynthesis	alcohol acetyltransferase
YHR194W	__________	+1.03	168888	173723	unknown	unknown
YJL071W	ARG2______	-1.03	161916	157085	arginine biosynthesis	acetylglutamate synthase
YKL068W	NUP100____	-1.14	156285	136785	nuclear protein targeting	nuclear pore protein
YLR003C	__________	-1.18	694224	588010	unknown	unknown
YLR375W	STP3______	+1.11	328608	363198	tRNA splicing	unknown
YMR110C	__________	+1.18	245124	289895	unknown	unknown; similar to aldehyde dehydrogenase
YNL162W	RPL42A____	+1.03	14868100	15329265	protein synthesis	ribosomal protein L42A
YOL068C	HST1______	+1.05	922262	965900	silencing	Sir2p homolog
YOR280C	__________	-1.01	366358	362564	unknown	unknown; similar to S. pombe dihydrofolate reductase
YMR325W	__________	+1.10	269924	297889	unknown	unknown
YBL080C	PET112____	-1.10	140444	127368	protein synthesis	translation of COX2 mRNA (mitochondrial)
YDL082W	RPL13A____	-1.10	11020811	10048112	protein synthesis	ribosomal protein L13A
YDR209C	__________	+1.20	422417	504986	unknown	unknown
YFR005C	SAD1______	-1.03	355364	344472	mRNA splicing, snRNP assembly	unknown
YGR010W	__________	-1.10	230675	209770	unknown	unknown
YHR023W	MYO1______	-1.09	336412	308251	cell wall biosynthesis	myosin heavy chain
YIL171W	HXT12_____	+1.01	160618	162798	transport	hexose permease
YJR049C	UTR1______	-1.03	352104	340376	unknown	putative ferric reductase
YKR046C	__________	+1.12	824428	925415	unknown	unknown
YLR203C	MSS51_____	-1.10	384766	350414	mRNA splicing, COX1 and COB mRNA	unknown
YL16A;_	__________	-1.01	110557	110002
YNR025C	__________	-1.09	653001	598478	unknown	unknown
YOR104W	__________	+1.01	321204	324079	unknown	unknown
YPL080C	__________	+1.05	282469	296172	unknown	unknown
YPR171W	__________	-1.12	233238	208896	unknown	unknown
YBR152W	SPP381____	-1.31	151725	115837	mRNA processing (putative)	U4/U6,U5 snRNP protein
YCR089W	FIG2______	+1.00	110144	110539	mating	extracellular, cell wall protein
YDR024W	__________	-1.13	184408	162898	unknown	unknown
YDR389W	SAC7______	-1.11	203212	182717	signaling	GTPase-activating protein for Rho1p
YER086W	ILV1______	-1.03	397457	386667	isoleucine and valine biosynthesis	threonine deaminase
YGL082W	__________	+1.03	297180	305431	unknown	unknown
YGR189C	CRH1______	+2.55	1047793	2670849	cell wall biogenesis (putative)	unknown; cell wall protein
YHR206W	SKN7______	-1.38	369709	266981	oxidative stress	transcription factor
YJL083W	__________	+1.03	177738	182900	unknown	unknown; similar to Irs4p
YKL080W	VMA5______	+1.09	942559	1022926	vacuolar acidification	vacuolar H+-ATPase V1 sector subunit
YLR015W	BRE2______	-1.23	329303	266745	secretion (putative)	unknown; brefeldin A sensitive
YLR387C	__________	+1.03	383059	395092	unknown	unknown
YMR121C	RPL15B____	+1.07	15415328	16547919	protein synthesis	ribosomal protein L15B
YNL174W	__________	-1.86	542313	291127	unknown	unknown
YOL080C	REX4______	-1.28	282474	220338	RNA processing	RNA exonuclease
YOR292C	__________	-1.15	243879	211946	unknown	unknown
YPL268W	PLC1______	-1.14	160499	140563	signaling	phosphoinositide-specific phospholipase C
YBL092W	RPL32_____	+1.07	4546769	4854579	protein synthesis	ribosomal protein L23
YDL094C	__________	+1.06	147266	156579	unknown	unknown
YDR217C	RAD9______	+1.20	99561	119961	DNA repair; DNA damage checkpoint	unknown
YFR017C	__________	+1.28	152351	195625	unknown	unknown
YGR022C	__________	+1.05	105945	111181	unknown	unknown
YHR035W	__________	+1.03	130151	133604	unknown	unknown; similar to Sec23p, expressed under
YIR005W	IST3______	+1.13	186496	211673	salt tolerance (putative)	unknown
YJR061W	__________	+1.14	215309	244519	unknown	unknown
YKR058W	GLG1______	+1.09	182820	199468	glycogen metabolism	glycogen synthesis initiator
YLR215C	CDC123____	+1.01	261361	262744	unknown	unknown
YMR315W	__________	+1.52	479063	730516	unknown	unknown
YNR037C	__________	+1.16	348798	404667	unknown	unknown; similar to prokaryotic ribosomal protein S19
YOR116C	RPO31_____	-1.29	783912	608526	transcription	RNA polymerase III 160 kD subunit
YPL092W	SSU1______	-1.39	401499	287902	sulfite tolerance	unknown; plasma membrane protein, major facilitator superfamily
YPR183W	DPM1______	-1.06	1269487	1192991	protein glycosylation	dolichol phosphate mannose synthase
YBR163W	DEM1______	+1.06	171530	181466	cell morphology (putative)	unknown; similar to Pta1p
YCR100C	__________	-1.03	114169	110598	unknown	unknown; similar to Pep1p, probably represents a fragmented coding region of a pseudogene
YDR401W	__________	+1.09	95901	104772	unknown	unknown
YER096W	SHC1______	+1.08	97175	105153	sporulation	unknown; may be involved in chitin synthesis
YGL094C	PAN2______	+1.09	118079	129088	mRNA processing	Pab1p-dependent poly(A) ribonuclease subunit
YGR201C	__________	+1.23	237045	292458	unknown	unknown; similar to translation elongation factors
YHR215W	PHO12_____	+1.81	1554741	2820743	phosphate metabolism	secreted acid phosphatase
YJL095W	BCK1______	+1.00	139845	140242	signaling, PKC1 pathway	serine-threonine protein kinase
YKL092C	BUD2______	+1.03	138277	142844	bud site selection	GTPase-activating protein for Rsr1p/Bud1p
YLR027C	AAT2______	+1.12	1051280	1181827	aspartate metabolism	aspartate aminotranferase,
YLR399C	BDF1______	-1.33	439946	330096	meiosis	putative chromatin component
YMR133W	REC114____	-1.04	164574	157954	meiosis, recombination	ds break formation complex subunit
YNL186W	UBP10_____	-1.30	494434	380689	protein degradation, ubiquitin-mediated	ubiquitin C-terminal hydrolase
YOL092W	__________	-1.32	977186	741078	unknown	unknown
YOR303W	CPA1______	-1.14	948594	832007	arginine biosynthesis	carbamoyl phosphate synthetase, arginine specific
YPL280W	__________	+1.06	116118	123616	unknown	unknown
YAL012W	CYS3______	-1.39	952452	685955	methionine biosynthesis	cystathionine gamma-lyase
YBR176W	ECM31_____	-1.11	200618	180130	cell wall biogenesis	unknown
YCRX06W	__________	-1.17	110835	94512
YDR047W	HEM12_____	-1.02	625620	610858	heme biosynthesis	uroporphyrinogen decarboxylase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDR414C	ERD1______	-1.09	233718	214293	secretion	ER protein retention
YER109C	FLO8______	-1.05	119708	114009	flocculation (and PHD)	FLO1 activator
YGL107C	__________	+1.13	111891	126785	unknown	unknown
YGR214W	RPS0A_____	-1.10	10958765	9927941	protein synthesis	ribosomal protein S0A
YIL011W	__________	-1.19	269758	226906	unknown	unknown; similar to Yil176p, Yir041p and other members of
YJL108C	__________	+1.30	227716	295292	unknown	unknown
YKL104C	GFA1______	+1.72	511914	880134	cell wall biogenesis	chitin biosynthesis
YLR038C	COX12_____	+1.21	528531	637849	oxidative phosphorylation	cytochrome-c oxidase, subunit VIb
YMR145C	__________	+1.24	1399321	1734584	unknown	unknown; similar to rotenone-insensitive NADH-ubiquinone
YNL199C	GCR2______	-1.13	331483	293323	glycolysis	transcriptional activator
YOR315W	__________	-1.15	313246	272010	unknown	unknown
YPR010C	RPA135____	-1.34	1303644	971231	transcription	RNA polymerase I 135 kD subunit
YBL103C	RTG3______	-1.28	139717	109155	glyoxylate cycle	CIT2 regulator
YCL010C	__________	-1.11	108795	97636	unknown	unknown
YDL107W	MSS2______	+1.06	176294	186258	mRNA splicing, COX1 mRNA	unknown
YDR230W	__________	+1.27	161261	204632	unknown	unknown
YEL011W	GLC3______	-1.03	114361	111170	cell wall biogenesis	glycogen branching enzyme
YFR030W	MET10_____	+1.05	166263	174455	sulfate assimilation	sulfite reductase subunit
YGR033C	__________	-1.10	353647	322000	unknown	unknown
YHR047C	AAP1______	-1.08	188492	174454	protein degradation	arginine/alanine aminopeptidase
YJR074W	MOG1______	+1.09	312827	340727	unknown	unknown; interacts with Gsp1p
YKR071C	__________	-1.27	652239	512199	unknown	unknown
YML097C	VPS9______	-1.11	357186	322388	vacuolar protein targeting	similar to mammalian ras inhibitors
YNL011C	__________	+1.02	185458	189676	unknown	unknown
YNR050C	LYS9______	-1.19	1762257	1477199	lysine biosynthesis	saccharopine dehydrogenase
YOR129C	__________	-1.09	248556	228240	unknown	unknown
YPL105C	__________	-1.04	576522	553518	unknown	unknown; similar to Smy2p
YPR196W	__________	+1.11	232871	258811	unknown	regulates MAL genes (YPD)
YAL024C	LTE1______	-1.07	124323	116317	cell cycle	GDP/GTP exchange factor
YBR188C	NTC20_____	+1.05	212753	224234	mRNA splicing	Prp19p-associated complex protein
YCRX18C	__________	-1.10	137329	125301
YDR059C	UBC5______	+1.25	149378	187106	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YDR426C	__________	+1.08	140893	152281	unknown	unknown
YER120W	SCS2______	-1.28	1256326	983770	inositol metabolism	regulator of INO1 expression
YGL119W	ABC1______	+1.01	164994	166466	respiration	ubiquinol-cyt.-c reductase assembly protein
YGR226C	__________	+1.20	110019	131637	unknown	unknown
YIL022W	TIM44_____	-1.28	321695	251569	mitochondrial protein targeting	inner membrane translocase component
YJL120W	__________	-1.09	146579	134941	unknown	unknown
YKL116C	__________	+1.14	121932	138432	unknown	putative protein kinase
YLR050C	__________	+1.35	323117	436116	unknown	unknown; similar to C-terminal region of human MAC30
YLR422W	__________	+1.01	325417	327768	unknown	unknown
YMR156C	__________	+1.07	174503	185930	unknown	unknown
YNL211C	__________	+1.03	182934	187701	unknown	unknown
YOL115W	TRF4______	-1.10	247095	224400	mitosis, chromosome condensation	unknown
YOR327C	SNC2______	+1.22	998416	1217911	secretion	post-Golgi v-SNARE
YPR022C	__________	-1.01	989206	980372	unknown	unknown
YBR002C	RER2______	-1.24	506926	409882	protein glycosylation	cis-prenytransferase
YCL023C	__________	-1.06	101626	95706	unknown	unknown
YDL119C	__________	-1.07	538644	505315	unknown	unknown
YEL022W	GEA2______	-1.15	508164	440921	secretion	GDP/GTP exchange factor for ARF
YFR039C	__________	-1.12	166916	149333	unknown	unknown
YGR040W	KSS1______	-1.00	134770	134609	pheromone signal transduction	protein kinase
YHR057C	CYP2______	+1.24	583018	722433	protein folding	peptidyl-prolyl cis-trans isomerase
YIR027C	DAL1______	+1.09	129488	140639	allantoin utilization	allantoinase
YJR087W	__________	+1.12	561565	626821	unknown	unknown
YKR083C	__________	+1.20	248874	298833	unknown	unknown; similar to paramyosin
YLR238W	__________	+1.02	199107	203067	unknown	unknown
YML107C	__________	-1.06	277647	261911	unknown	unknown
YNL023C	FAP1______	-1.41	397144	282613	transcription (putative)	FKBP12-binding protein
YNR062C	__________	-1.13	144776	128223	unknown	unknown; similar to Haemophilus influenzae L-lactate
YOR141C	ARP8______	-1.10	154297	140742	cytoskeleton (putative)	actin-related protein
YPL117C	IDI1______	+1.05	1413880	1478005	isoprenoid biosynthesis	isopentenyl-diphosphate delta-isomerase
YAL034C	FUN19_____	-1.04	151092	145308	unknown	unknown
YBR200W	BEM1______	-1.21	287396	237932	bud emergence	binds Cdc24p
YDR071C	__________	+1.18	1279453	1507748	unknown	unknown
YDR438W	__________	+1.01	181347	183206	unknown	unknown
YER132C	PMD1______	-1.08	463630	430589	meiosis	gene expression regulator (putative)
YGL131C	__________	-1.17	1505856	1286585	unknown	unknown
YGR238C	KEL2______	+1.02	164072	167032	unknown	unknown; similar to Kel1p and Kel3p
YIL034C	CAP2______	-1.21	577437	477653	cytoskeleton	F-actin capping protein subunit
YJL132W	__________	-1.08	175756	162173	unknown	unknown; similar to phospholipase D
YKL128C	PMU1______	-1.41	513161	363150	unknown	phosphomutase homolog; suppresses ts tps2 mutant
YLR062C	__________	-1.02	5806351	5684491	unknown	unknown
YLR432W	IMD3______	-1.64	2818708	1723073	unknown	unknown; similar to Pur5p and inosine-5'-monophosphate dehydrogenase of human and E. coli
YMR167W	MLH1______	-1.06	233677	220911	DNA repair	MutL homolog; mismatch repair
YNL223W	AUT2______	-1.23	220768	178778	autophagy	microtubule-associated protein (putative)
YOL127W	RPL25_____	-1.02	15184260	14887725	protein synthesis	ribosomal protein L25
YOR339C	UBC11_____	-1.16	229281	197451	protein degradation, ubiquitin-mediated (putative)	homolog of ubiquitin carrier protein E2-C
YPR034W	ARP7______	-1.31	489427	372202	cytoskeleton (putative)	actin-related protein
YBR012W	TY1B______	+1.20	15958128	19078653	unknown	unknown
YCL035C	GRX1______	-1.12	801527	715057	oxidative stress response	glutaredoxin
YDR254W	CHL4______	+1.08	423066	455643	mitosis, chromosome segregation	unknown
YEL034W	HYP2______	-1.04	9390412	9017177	protein synthesis	translation initiation factor eIF5A
YFR051C	RET2______	-1.14	1375506	1211074	secretion	vesicle coat component
YGR052W	__________	-1.04	190580	182544	unknown	unknown
YHR068W	DYS1______	-1.66	1030877	620349	hypusine biosynthesis	deoxyhypusine synthase
YIR039C	YPS6______	+1.12	151588	169133	protein degradation	GPI-anchored aspartic protease
YJR098C	__________	+1.02	161536	164547	unknown	unknown
YKR095W	MLP1______	-1.03	108200	105452	DNA repair (putative)	myosin-like protein
YLR250W	SSP120____	+1.23	672043	825931	secretion	unknown
YML118W	__________	+1.11	138938	153967	unknown	unknown
YNL035C	__________	-1.31	428721	326504	unknown	unknown
YNR074C	__________	-1.04	228950	220663	unknown	unknown; similar to Bacillus subtilis nitrite reductase
YOR151C	RPB2______	-1.23	818543	666581	transcription	RNA polymerase II 140 kDa subunit
YPL129W	ANC1______	+1.04	1296447	1345847	transcription	TFIIF 30 kD subunit
YAL044C	GCV3______	+1.30	1386680	1802113	glycine metabolism	glycine decarboxylase
YBR212W	NGR1______	-1.00	383613	381710	unknown	glucose-repressible RNA-binding protein
YDR083W	__________	-1.26	962115	765706	unknown	unknown
YDR450W	RPS18A____	-1.08	13148240	12160963	protein synthesis	ribosomal protein S18A
YER142C	MAG1______	-1.26	312098	248561	DNA repair	3-methyladenine DNA glycosylase

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YGL143C	MRF1______	+1.04	233584	242950	protein synthesis	mitochondrial peptide chain release factor
YGR250C	__________	+1.52	256616	389378	unknown	unknown
YIL046W	MET30_____	-1.10	248324	226121	sulfur amino acid metbolism	F-box transcription factor
YJL144W	__________	+1.04	173442	180303	unknown	unknown
YKL140W	TGL1______	-1.10	181273	165380	glycerolipid metabolism	triglyceride lipase-cholesterol esterase
YLR074C	__________	-1.36	670068	491859	unknown	unknown
YLR444C	__________	+1.00	348853	350296	unknown	unknown
YMR177W	MMT1______	-1.02	233644	229065	mitochondrial iron transport	transmembrane domain (4) protein
YNL235C	__________	+1.17	364192	427245	unknown	unknown
YOL139C	CDC33_____	-1.12	3436473	3071387	protein synthesis	translation initiation factor eIF4E
YOR349W	CIN1______	-1.14	153108	134003	mitosis, chromosome segregation	unknown
YPR046W	MCM16_____	+1.07	268868	287942	mitosis,chromosome segregation	unknown
YBR024W	SCO2______	+1.03	86055	88300	respiration	Cox1p and Cox2p stability (putative)
YCL047C	__________	+1.33	243399	324325	unknown	unknown
YDL141W	BPL1______	-1.16	229865	198383	protein processing	biotin:apoprotein ligase
YDR262W	__________	-1.06	356573	335646	unknown	unknown
YEL046C	GLY1______	-1.29	366311	284328	glycine, serine, and threonine metabolism	L-threonine aldolase
YGR064W	__________	+1.17	413555	485259	unknown	unknown
YHR079C	IRE1______	-1.04	110479	106272	protein folding	sensor of unfolded proteins in the ER
YJR110W	__________	+1.11	162117	179929	unknown	unknown
YLR259C	HSP60_____	-1.18	788684	667201	protein folding	mitochondrial chaperonin
YML130C	ERO1______	-1.05	461831	441883	protein folding	protein disulfide bond formation in the ER
YNL045W	__________	-1.11	328686	296090	unknown	unknown; similar to leukotriene A4 hydrolases and zinc-containing aminopeptidases
YOR163W	DDP1______	+1.24	938808	1160822	dinucleoside polyphosphate metabolism	diadenosine and diphosphoinositol polyphosphate phosphohydrolase
YPL141C	__________	-1.12	373003	334030	unknown	unknown; similar to Kin4p
YAL058W	CNE1______	-1.12	231780	207121	secretion	calnexin and calreticulin homolog
YBR224W	__________	+1.06	79875	84817	unknown	unknown
YDR095C	__________	+1.08	140020	150640	unknown	unknown
YDR462W	MRPL28____	+1.08	226698	244151	protein synthesis	ribosomal protein, mitochondrial L28
YER152C	__________	-1.02	326079	318934	unknown	unknown
YGL155W	CDC43_____	-1.30	260041	199652	protein processing	geranylgeranyltransferase subunit
YGR262C	__________	-1.12	498745	445885	unknown	unknown; similar to apple tree calcium/calmodulin-binding
YIL058W	__________	-1.33	196211	148000	unknown	unknown
YJL156C	SSY5______	-1.22	184950	151596	transport, amino acid (putative)	unknown
YKL152C	GPM1______	+1.02	15156429	15412777	glycolysis	phosphoglycerate mutase
YLR086W	SMC4______	-1.32	270651	205279	mitosis, chromosome condensation and segregation	unknown
YLR456W	__________	-1.02	205465	200948	unknown	unknown
YMR189W	GCV2______	-1.05	143828	136649	amino acid metabolism	glycine decarboxylase P subunit
YNL247W	__________	-1.24	1771968	1423801	protein synthesis	tRNA synthetase, cysteinyl
YOL151W	GRE2______	-1.16	654487	566563	unknown	unknown; induced by osmotic stress
YOR361C	PRT1______	-1.28	1150976	896912	protein synthesis	translation initiation factor eIF3 subunit
YPR058W	YMC1______	-1.17	585936	501248	transport	(putative) mitochondrial carrier
YBR036C	CSG2______	-1.05	757281	718394	sphingolipid metabolism	mannosylation
YCL059C	KRR1______	-1.20	1141534	954574	unknown	essential
YDL153C	SAS10_____	-1.71	872424	511137	silencing	nuclear protein, reulator of silencing at HML, HMR, telomeres
YDR274C	__________	-1.13	160241	142039	unknown	unknown
YEL058W	PCM1______	+1.53	437626	668455	aminosugars metabolism	phosphoacetylglucosamine mutase
YGR076C	MRPL25____	-1.09	221228	203286	protein synthesis	ribosomal protein, mitochondrial L25
YHR090C	YNG2______	+1.03	231948	238211	chromatin structure	histone acetyltransferase complex subunit
YJR122W	CAF17_____	+1.01	256099	259294	catabolite repression	component of CCR4 transcriptional complex
YLR270W	__________	+1.01	324479	329250	unknown	unknown
YMR009W	__________	+1.15	571554	657674	unknown	unknown; similar to MMSAB operon regulatory protein
YNL055C	POR1______	+1.10	2461981	2698966	transport	mitochondrial outer membrane porin
YOR175C	__________	-1.29	453952	351367	unknown	unknown
YPL153C	RAD53_____	+1.09	125757	136678	cell cycle, checkpoint	protein kinase
YAR002C	ERP1______	+1.05	97264	101740	membrane trafficking; secretion (putative)	unknown
YBR236C	ABD1______	-1.12	326012	291789	mRNA capping	mRNA cap methyltransferase
YDR105C	__________	+1.04	344182	358156	unknown	unknown
YDR474C	__________	+1.04	181675	188158	unknown	unknown
YER162C	RAD4______	-1.04	189911	182718	DNA repair, nucleotide excision	repairosome component
YGL167C	PMR1______	-1.09	219205	202018	transport	Ca(2+) ATPase
YGR274C	TAF145____	-1.11	185429	166327	transcription	TFIID 145 kD subunit
YJL168C	SET2______	-1.40	414979	296855	galactose regulation	transcriptional repressor of Gal4
YKL164C	PIR1______	+1.04	3946569	4108997	unknown	unknown; Pir1p/Hsp150p/Pir3p family
YLR098C	CHA4______	-1.02	111728	109785	ser/thr metabolism	CHA1 activator
YMR200W	ROT1______	+1.28	351213	447814	cytoskeleton	unknown
YNL259C	ATX1______	+1.38	299779	415091	oxidative stress response	unknown
YOL163W	__________	-1.10	151680	138412	unknown	unknown; similar to Pseudomonas putida phthalate transporter
YOR373W	NUD1______	+1.01	116109	117644	chromatin structure	nucleosome assembly protein
YPR070W	MED1______	+1.10	110462	121871	transcription	RNA polymerase II mediator subunit
YBR048W	RPS11B____	+1.01	15525334	15709785	protein synthesis	ribosomal protein S11B
YCL074W	__________	-1.85	560684	302686	unknown	unknown
YDL165W	CDC36_____	-1.20	288982	240757	transcription	general negative regulator
YDR286C	__________	+1.01	317761	320136	unknown	unknown
YEL069C	HXT13_____	-1.32	379645	286635	transport	hexose permease
YGR088W	CTT1______	+1.06	131762	139972	oxidative stress response	catalase T
YHR102W	KIC1______	-1.07	164305	153327	mitosis (putative)	protein kinase; interacts with Cdc31p
YJR134C	SGM1______	-1.03	329794	320139	unknown; growth on galactose or mannose	unknown
YLR282C	__________	-1.00	101481	101077	unknown	unknown
YMR021C	MAC1______	-1.01	326834	324697	metal-dependent gene regulation	transcription factor
YNL067W	RPL9B_____	+1.21	15824537	19079254	protein synthesis	ribosomal protein L9B
YOR187W	TUF1______	-1.16	1136729	980839	protein synthesis	translation elongation factor Tu, mitochondrial
YPL165C	__________	+1.02	219847	223517	unknown	unknown
YAR023C	__________	-1.02	151028	147557	unknown	unknown; similar to subtelomerically-encoded proteins
YBR248C	HIS7______	+1.15	556021	638313	histidine biosynthesis	glutamine amidotransferase:cyclase
YDR117C	__________	+1.03	308566	317866	unknown	unknown
YDR486C	__________	+1.20	377952	455009	unknown	unknown; similar to Snf7p
YGL179C	__________	+1.04	120609	125092	unknown	putative protein kinase
YGR286C	BIO2______	-1.33	330140	247335	biotin biosynthesis	biotin synthetase
YIL079C	__________	-1.22	520194	426366	unknown	unknown; similar to gag polyprotein
YJL180C	ATP12_____	+1.13	331223	373852	ATP synthesis	F1F0-ATPase complex assembly
YKL176C	LST4______	-1.08	290567	269944	secretion	unknown; involved in secretion of nitroge- regulated permease
YLR110C	__________	+1.32	13931521	18388711	unknown	unknown; similar to Flo1p, Fig2p, Flo5p, Yal063p, and Ykr102p
YMR212C	EFR3______	-1.30	466284	359424	unknown	unknown; similar to myosin heavy chains; null requires PHO85
YNL271C	BNI1______	-1.02	154791	151664	bud site selection, bipolar	interacts with Rho1p
YOR009W	__________	+1.55	1236635	1911493	unknown	unknown; similar to PAU1 family
YOR385W	__________	+1.08	345801	372060	unknown	unknown
YPR082C	DIB1______	+1.13	422235	478328	unknown	unknown; similar to S. pombe dim1+
YBR060C	ORC2______	-1.13	366533	325204	DNA replication	origin recognition complex, 72 kD subunit
YCLX10C	__________	-1.02	237761	232210

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YDL177C	__________	+1.17	253736	296640	unknown	unknown
YDR298C	ATP5______	+1.20	918518	1105264	ATP synthesis	F1F0-ATPase subunit
YER003C	PMI40_____	+1.13	878210	996014	mannose metabolism	mannose-6-phosphate isomerase
YGR100W	MDR1______	-1.05	136523	129838	unknown	unknown
YHR114W	BZZ1______	-1.15	545985	475440	cytoskeleton (putative)	actin assembly complex component
YJR146W	__________	-1.33	198406	148949	unknown	unknown
YLR293C	GSP1______	-1.11	7351911	6595838	nuclear protein targeting	GTP-binding protein, ras superfamily
YMR032W	HOF1______	-1.14	250816	220038	cytokinesis	unknown
YNL079C	TPM1______	+1.02	2444004	2502801	cytoskeleton	tropomyosin
YOR197W	__________	-1.13	854810	759779	unknown	unknown
YPL177C	CUP9______	+1.01	621903	631092	Cu2+ ion homeostasis	putative DNA binding protein
YAR044W	OSH1______	-1.04	353580	338700	sterol biosynthesis (putative)	similar to human oxysterol binding protein
YBR260C	RGD1______	-1.14	237571	208837	unknown	GTPase-activating (GAP) protein (putative)
YDR129C	SAC6______	-1.00	822084	818352	cytoskeleton	fimbrin homolog
YDR498C	SEC20_____	-1.01	350098	347075	secretion	unknown; ER membrane protein
YER184C	__________	+1.14	148815	169789	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YGL191W	COX13_____	+1.23	1193234	1473533	oxidative phosphorylation	cytochrome-c oxidase subunit VIa
YIL090W	__________	-1.20	331050	275407	unknown	unknown
YJL192C	__________	-1.10	764447	693882	unknown	unknown; similar to E. coli
YKL188C	PXA2______	-1.06	152870	144557	transport	peroxisomal fatty acid transporter, ABC family
YLR122C	__________	+1.03	109104	112660	unknown	unknown
YNL283C	WSC2______	+1.11	411004	454657	cell wall biogenesis	alpha-1,4-glucan-glucosidase
YOR021C	__________	-1.34	1667506	1239828	unknown	unknown
YPR094W	__________	+1.10	338355	371284	unknown	unknown
YBR072W	HSP26_____	-1.03	90382	87910	diauxic shift	stress-induced protein
YCR010C	__________	+1.02	135665	138663	unknown	unknown
YDL189W	__________	-1.03	425275	413818	unknown	unknown
YDR310C	SUM1______	-1.04	128179	123804	silencing	nuclear protein
YER013W	PRP22_____	-1.06	219797	206477	mRNA splicing	RNA helicase
YGR110W	__________	+1.18	126091	148429	unknown	unknown
YHR126C	__________	+1.13	229830	258856	unknown	unknown; similar to members of the Pir1p/Hsp150p/Pir3p
YJR158W	HXT16_____	+1.03	166583	171037	transport	hexose permease
YLR305C	STT4______	-1.18	515316	436778	signaling, PKC1 pathway	phosphatidylinositol-4-kinase
YMR044W	IOC4______	-1.04	370278	356893	unknown	unknown
YNL091W	__________	-1.19	639725	537630	unknown	unknown; similar to Uso1p and human NF2 neurofibromatosis
YOR209C	NPT1______	+1.00	1214437	1218620	NAD biosynthesis	nicotinate phosphoribosyltransferase
YPL188W	POS5______	-1.09	354761	326713	unknown	unknown; similar to Utr1p and Yel041p
YBL009W	__________	-1.61	236792	146928	unknown	unknown
YBR272C	HSM3______	-1.29	232255	179655	mismatch repair	unknown; MutS homolog
YDL011C	__________	-1.23	144338	117685	unknown	unknown
YDR141C	DOP1______	+1.00	624740	626915	unknown	unknown; similar to Yps1p and E. nidulans dopA
YDR510W	SMT3______	+1.12	1569381	1762947	protein degradation	ubiquitin-like protein
YFL009W	CDC4______	-1.34	510254	381771	cell cycle	SCF-Cdc4p complex component
YGL203C	KEX1______	+1.06	669051	708023	secretion	carboxypeptidase (YSC-alpha)
YIL101C	XBP1______	-1.10	248814	226692	stress response	transcriptional repressor
YJL204C	__________	-1.06	792494	745545	unknown	unknown; similar to Tor2p, member of a family of
YKL200C	__________	-1.02	140723	137313
YLR134W	PDC5______	-1.35	11224788	8295010	glycolysis	pyruvate decarboxylase
YMR236W	TAF17_____	-1.23	621131	503180	transcription	TFIID 17 kD subunit
YNL293W	MSB3______	+1.17	213802	250977	unknown	unknown; suppresses bud emergence mutant
YOR033C	DHS1______	+1.04	236215	245363	DNA repair	exonuclease; also recombination
YPL011C	TAF47_____	-1.02	327270	321332	transcription	component of TAF(II) complex
YPR106W	ISR1______	+1.03	402248	412492	staurosporine resistance	protein kinase
YBR084C	RPL19A____	+1.09	15699086	17099353	protein synthesis	ribosomal protein L19A
YCR021C	HSP30_____	-1.11	376538	339666	diauxic shift	plasma membrane heat shock protein
YDL201W	__________	-1.58	503279	318409	unknown	unknown
YDR320C	__________	-1.37	374586	274090	unknown	unknown; similar to human transformation-sensitive
YER023W	PRO3______	-1.22	440518	361394	proline biosynthesis	delta 1-pyrroline-5-carboxylate reductase
YGL011C	SCL1______	-1.09	1306665	1197606	protein degradation	20S proteasome subunit YC7ALPHA/Y8
YGR122W	__________	+1.04	225638	234695	unknown	unknown
YHR137W	ARO9______	+1.04	249171	259864	aromatic amino acid metabolism	aromatic amino acid aminotransferase II
YJL011C	__________	+1.09	299999	327082	unknown	unknown
YKL010C	UFD4______	+1.15	102171	117289	protein degradation, ubiquitin-mediated	unknown; may influence multi-Ub chain topology
YLL011W	SOF1______	-1.07	513511	478133	rRNA processing	nucleolar snRNP protein
YLR316C	TAD3______	+1.02	221659	225360	tRNA processing	tRNA-specific adenosine deaminase subunit
YMR053C	STB2______	+1.09	138255	151018	unknown	binds Sin3p
YNL103W	MET4______	-1.01	400950	396246	sulfur amino acid metabolism	transcriptional activator
YOL011W	PLB3______	-1.09	333304	304715	phospholipid metabolism	phospholipase B
YOR221C	MCT1______	-1.26	336820	268324	fatty acid metabolism	malonyl-CoA:ACP transferase
YPL200W	__________	-1.05	109056	103641	unknown	unknown
YAR070C	__________	+1.05	106904	111893	unknown	unknown
YBL021C	HAP3______	-1.03	268134	259566	transcription	component of heterotrimeric CCAAT-binding factor
YBR284W	__________	-1.01	99948	98910	unknown	unknown; similar to AMP deaminase
YDL023C	__________	-1.59	153550	96627	unknown	unknown
YDR153C	__________	-1.33	194798	146414	unknown	unknown
YDR522C	SPS2______	-1.08	111328	103503	meiosis	unknown
YGL215W	CLG1______	-1.04	364448	350273	cell cycle	cyclin-like (Pho85p)
YHL019C	APM2______	+1.17	170940	199779	endocytosis	AP-2 complex subunit
YIL113W	__________	+1.10	119977	132376	unknown	protein phosphatase
YJL216C	__________	+1.07	134737	144724	unknown	unknown; similar to Mal62p (glucosidase P1)
YKL212W	SAC1______	-1.14	328574	287326	secretion	ER/Golgi ATP/ADP exchanger
YLR146C	SPE4______	-1.03	329374	319813	spermine biosynthesis	spermine synthase
YML020W	__________	-1.04	173689	167325	unknown	unknown
YMR247C	__________	-1.11	609831	547016	unknown	unknown
YNL305C	__________	+1.25	272576	341468	unknown	unknown; similar to Aspergillus nidulans negative-acting
YOR045W	TOM6______	-1.12	496049	444594	mitochondrial protein targeting	outer membrane translocase component
YPL023C	MET12_____	-1.32	359269	273008	methionine biosynthesis	methylenetetrahydrofolate reductase
YPR118W	__________	-1.07	971222	906272	unknown	unknown
YBR094W	__________	-1.27	360003	284302	unknown	unknown; similar to Mec1p and porcine tubulin-tyrosine
YCR031C	RPS14A____	-1.22	7214343	5906034	protein synthesis	ribosomal protein S14A
YDL213C	__________	-1.16	895671	769015	unknown	unknown
YDR332W	__________	-1.15	203372	177093	unknown	unknown; similar to DEAD box family helicases
YER035W	EDC2______	+1.09	277117	302470	mRNA processing	unknown; genetic interaction with dcp2-7
YGL023C	PIB2______	-1.04	255422	246114	signaling (putative)	unknown; binds phosphatidylinositol 3-phosphate
YGR134W	__________	+1.07	111514	119140	unknown	unknown
YHR147C	MRPL6_____	-1.00	442588	441688	protein synthesis	ribosomal protein, mitochondrial L6
YJL023C	PET130____	+1.21	190426	230322	protein synthesis, mitochondrial	unknown
YKL022C	CDC16_____	+1.10	212501	233425	cell cycle	anaphase-promoting complex subunit
YLL023C	__________	+1.14	358386	408085	unknown	unknown
YLR328W	__________	-1.07	363068	340322	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YMR065W	KAR5______	-1.02	209463	205230	mating; nuclear fusion	coiled-coil membrane protein
YNL115C	__________	+1.32	168722	222823	unknown	unknown
YOL023W	IFM1______	-1.12	171282	153444	protein synthesis	translation initiation factor 2, mitochondrial
YOR233W	KIN4______	-1.12	417896	374265	unknown	protein kinase
YPL212C	PUS1______	-1.41	551013	391409	tRNA processing	pseudouridine synthase
YBL033C	RIB1______	+1.10	78177	86099	flavin biosynthesis	GTP cyclohydrolase II
YBR296C	PHO89_____	+1.58	193644	306829	phosphate metabolism	Na+/Pi symporter
YDL035C	GPR1______	-1.03	276243	267066	signaling, pheromone pathway	G-protein coupled receptor, coupled to Gpa2p
YDR165W	__________	-1.25	996053	796157	unknown	unknown
YDR534C	__________	-1.16	193310	167247	unknown	unknown
YFL028C	CAF16_____	+1.05	410492	430824	transport	ATP-binding cassette (ABC) family
YGL226W	__________	+1.27	217614	275643	unknown	unknown; similar to Neurospora cytochrome-c oxidase
YIL125W	KGD1______	+1.05	233460	246082	respiration	alpha-ketoglutarate dehydrogenase
YJR004C	SAG1______	-1.58	1277504	807938	mating	alpha-agglutinin
YKL224C	__________	+1.22	241270	295550	unknown	unknown; similar to Ybr301p, member of the PAU1 family
YML031W	NDC1______	-1.18	454420	384415	cytoskeleton	spindle pole body duplication
YMR260C	TIF11_____	-1.01	5580272	5549419	protein synthesis	translation initiation factor eIF1a
YNL317W	PFS2______	-1.04	329617	316685	mRNA processing	polyadenylation factor subunit
YOR057W	SGT1______	-1.09	367100	336766	mitosis (putative)	unknown; suppresses skp1 mutation
YPL035C	__________	-1.04	207007	199383	unknown	unknown
YPR130C	__________	-1.08	884236	821095	unknown	unknown
YBR106W	PHO88_____	-1.02	2824888	2772902	phosphate transport	regulator of Pho81
YCR043C	__________	+1.03	467072	480155	unknown	unknown
YDL225W	SHS1______	-1.06	411649	388532	cytokinesis	septin (putative)
YDR344C	__________	-1.03	117142	113435	unknown	unknown
YER045C	__________	-1.07	269639	251083	unknown	unknown
YGL035C	MIG1______	-1.16	200288	172546	glucose repression	transcriptional repressor
YGR146C	__________	+1.31	216203	283188	unknown	unknown
YHR159W	__________	+1.03	128805	132851	unknown	unknown
YJL035C	TAD2______	+1.05	315477	329780	tRNA processing	tRNA-specific adenosine deaminase subunit
YLL035W	GRC3______	-1.47	412786	280408	unknown	unknown; essential
YLR340W	RPP0______	-1.01	14174387	14013415	protein synthesis	ribosomal protein L10, acidic
YMR076C	PDS5______	-1.23	531834	432786	mitosis, sister chromatid cohesion	unknown
YNL127W	__________	-1.16	197200	170183	unknown	unknown; similar to Fus2p
YOL035C	__________	+1.04	414668	432514	unknown	unknown
YOR245C	__________	+1.02	350672	357581	unknown	unknown
YPL224C	MMT2______	-1.03	277849	269711	mitochondrial ion transport	transmembrane domain (2) protein
YBL045C	COR1______	-1.04	940281	905199	oxidative phosphorylation	ubiquinol cytochrome-c reductase
YDL047W	SIT4______	-1.13	453860	400508	cell cycle	type 2A related protein phosphatase
YDR175C	__________	-1.01	233797	231921	unknown	unknown
YFL038C	YPT1______	+1.06	905199	955165	secretion	rab GTPase; ER-to-Golgi
YGL238W	CSE1______	-1.17	962930	822254	mitosis, chromosome segregation	kinetochore protein (putative)
YHL042W	__________	-1.10	146451	132858	unknown	unknown; similar to subtelomerically-encoded proteins
YIL137C	__________	-1.03	217972	210691	unknown	unknown; similar to aminopeptidases
YJR015W	__________	+1.00	439363	440216	unknown	unknown; similar to Sng1p and multidrug resistance proteins
YKR011C	__________	+1.12	179226	201200	unknown	unknown
YLR168C	(MSF1)____	+1.21	253319	305369	unknown	intramitochondrial protein sorting (putative)
YML041C	__________	+1.14	223182	253950	unknown	unknown
YMR272C	SCS7______	-1.23	601582	488111	fatty acid metabolism	ceramide hydroxylase
YNL329C	PEX6______	-1.10	366854	332566	peroxisome biogenesis	ATPase (putative)
YOR069W	VPS5______	+1.04	341728	355794	vacuolar protein targeting	sorting nexin family
YPL047W	__________	-1.17	794897	678089	unknown	unknown
YPR140W	__________	-1.06	307542	289272	unknown	unknown; similar to human Barth syndrome gene tafazzin
YBR117C	TKL2______	-1.53	272571	178698	pentose phosphate cycle	transketolase
YCR055C	__________	-1.29	713068	550675
YDL237W	__________	-1.03	422157	408599	unknown	unknown
YDR356W	NUF1______	-1.37	230792	168139	cytoskeleton	spindle pole body component
YER056C	FCY2______	-1.14	12576306	10987014	transport	purine-cytosine permease
YGL047W	__________	-1.07	357219	335363	unknown	unknown; similar to Plasmodium falciparum gametocytogenesis
YGR158C	MTR3______	-1.04	373404	359582	mRNA transport	nucleolar protein
YHR171W	APG7______	+1.15	145981	167958	autophagy	unknown; similar to ubiquitin-activating enzymes
YJL048C	__________	+1.36	310201	420837	unknown	unknown
YKL045W	PRI2______	+1.03	210886	218235	DNA replication	polymerase alpha 58 kD subunit (DNA primase)
YLL047W	__________	+1.12	162159	182349	unknown	unknown
YLR352W	__________	+1.03	146193	150156	unknown	unknown
YMR087W	__________	+1.07	299095	318796	unknown	unknown
YNL139C	RLR1______	-1.11	420675	380220	transcription	pleiotropic regulatory protein
YOL047C	__________	-1.01	135669	134602	unknown	unknown
YOR257W	CDC31_____	+1.08	589151	637758	cytoskeleton	spindle pole body component
YPL236C	__________	-1.13	161007	142596	unknown	unknown
YBL057C	__________	+1.02	609289	621104	unknown	unknown
YDL059C	RAD59_____	+1.02	140616	143609	DNA repair and recombination	unknown
YDR186C	__________	-1.04	187200	180710	unknown	unknown
YFL050C	ALR2______	-1.08	112195	104135	aluminum resistance	ion transporter (putative)
YGL250W	__________	+1.07	134300	143856	unknown	unknown
YHR002W	__________	-1.01	229454	226713	unknown	unknown; similar to Grave's disease protein; mitochondrial carrier (MCF) family
YIL149C	MLP2______	-1.27	758958	596803	nuclear protein targeting (putative)	unknown; similar to Mlp1p
YJR026W	__________	-1.24	3449112	2781570	unknown	unknown; similar to Hyr1p, Ybr244p, and glutathione peroxidases
YKR023W	__________	-1.03	304181	294856	unknown	unknown
YLR180W	SAM1______	-1.26	2216488	1760510	methionine metabolism	S-adenosylmethionine synthetase
YML051W	GAL80_____	-1.16	376820	325500	galactose regulation	transcriptional repressor
YMR284W	YKU70_____	+1.00	150879	151303	DNA repair	DNA binding; Ku70 homolog
YNR002C	FUN34_____	+1.04	165164	171266	unknown	unknown
YOR081C	__________	-1.09	260681	239784	unknown	unknown
YPL059W	GRX5______	+1.14	778976	889707	oxidative stres response	glutaredoxin
YPR152C	__________	-1.09	144241	132747	unknown	unknown; similar to Ykl012p
YBR129C	OPY1______	-1.03	387007	377041	mating	unknown
YCR067C	SED4______	-1.01	385526	380567	secretion	ER vesicle formation
YDR001C	NTH1______	+1.30	311738	405623	trehalose metabolism	alpha, alpha-trehalase
YDR366C	__________	-1.18	11262939	9520399	unknown	unknown
YER066W	__________	-1.04	276449	266894	unknown	unknown; similar to Cdc4p, has one WD (WD-40) domain
YGL059W	__________	+1.05	167534	175718	unknown	unknown; similar to Rat branched-chain alpha-ketoacid
YGR166W	KRE11_____	+1.17	354808	413470	cell wall biogenesis	regulates beta-1,6-glucan synthesis
YHR183W	GND1______	-1.03	2140554	2073301	pentose phosphate cycle	6-phosphogluconate dehydrogenase, decarboxylating
YJL060W	__________	+1.34	378238	508372	unknown	unknown; similar to kynurenine aminotransferase
YKL057C	NUP120____	-1.08	241249	222502	nuclear protein targeting	nuclear pore protein
YLL059C	__________	-1.02	107948	105591	unknown	unknown
YLR364W	__________	+1.26	120008	150762	unknown	unknown; similar to yeast glutaredoxin-like protein
YMR099C	__________	+1.15	1045395	1199854	unknown	unknown
YNL151C	RPC31_____	-1.36	1010669	740956	transcription	RNA polymerase III 31 kD subunit

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOL057W	__________	-1.26	558389	444923	unknown	unknown
YOR269W	PAC1______	-1.13	222756	196910	cytoskeleton (putative)	unknown; required in the absence of Cin8p
YPL248C	GAL4______	-1.04	133388	128770	galactose regulation	transcriptional activator
YBL069W	AST1______	-1.22	305513	250529	plasma membrane protein targeting	targets plasma membrane ATPase
YDL071C	__________	-1.06	121018	113868	unknown	unknown
YDR198C	__________	-1.13	265538	235567	unknown	unknown
YFL062W	COS4______	+1.52	1302577	1975075	unknown	unknown; similar to subtelomerically-encoded proteins
YGL262W	__________	-1.06	131399	124276	unknown	unknown
YHR013C	ARD1______	-1.04	1100014	1054775	protein processing	protein N-acetyltransferase subunit
YIL160C	POT1______	+1.06	140505	149178	fatty acid metabolism	peroxisomal 3-oxoacyl CoA thiolase
YJR038C	__________	-1.02	131328	128551	unknown	unknown
YKR035C	__________	-1.08	574808	531324	unknown	unknown
YLR192C	HCR1______	-1.11	969170	869252	unknown	unknown; high copy suppressor of rpg1
YML062C	MFT1______	-1.17	415739	354782	mitochondrial protein targeting	mitochondrial targeting protein
YNR014W	__________	-1.13	264605	233347	unknown	unknown
YOR093C	__________	-1.04	352504	337698	unknown	unknown
YPL069C	BTS1______	+1.03	355075	365710	protein processing	geranylgeranyl diphosphate synthase
YPR160W	GPH1______	+1.03	115620	118707	glycogen metabolism	glycogen phosphorylase
YBR141C	__________	-1.14	261015	229835	unknown	unknown
YCR079W	__________	+1.02	158992	162581	unknown	protein phosphatase
YDR013W	__________	+1.04	178645	185978	unknown	unknown
YDR378C	LSM6______	+1.18	677354	800173	mRNA splicing (putative)	unknown; similar to snRNA-associated protein
YER075C	PTP3______	+1.01	335758	339820	signaling, pheromone and high osmolarity pathways	protein tyrosine phosphatase
YGL071W	RCS1______	-1.04	112126	108123	iron transport	transcriptional activator
YGR178C	PBP1______	-1.34	417865	312433	mRNA processing	poly(A)-binding protein binding protein
YHR195W	NVJ1______	+1.01	273460	276942	vacuolar protein targeting (putative)	unknown; Vac8p binding protein
YJL072C	__________	+1.13	209516	236210	unknown	unknown
YKL069W	__________	+1.12	297933	332278	unknown	unknown
YLR004C	__________	+1.06	289266	306204	unknown	unknown; similar to allantoate transport protein
YLR376C	__________	+1.21	122881	148853	unknown	unknown
YMR111C	__________	-1.00	150724	150203	unknown	unknown; similar to Msn1p
YNL163C	__________	-1.12	264146	236645	protein synthesis	translation elongation factor eEF4
YOL069W	NUF2______	+1.03	355341	365979	cytoskeleton	spindle pole body component
YOR281C	PLP2______	-1.13	816937	725325	unknown	unknown; similar to phosducins
YMR326C	__________	+1.01	120361	121980	unknown	unknown; similar to members of the PAU1 family
YBL081W	__________	-1.14	749634	657445	unknown	37% identity to Drosophila l not protein
YDL083C	RPS16B____	-1.13	12963941	11441299	protein synthesis	ribosomal protein S16B
YDR210W	__________	+1.45	841120	1222697	unknown	unknown
YFR006W	__________	-1.08	790272	734945	unknown	unknown; similar to human X-pro dipeptidase
YGR011W	__________	+1.09	255550	278311	unknown	unknown
YHR024C	MAS2______	-1.10	418294	379128	protein processing	mitochondrial processing protease subunit
YJR050W	ISY1______	+1.03	317182	326550	mRNA splicing	unknown; interacts with spliceosome
YKR047W	__________	+1.19	1267060	1505057	unknown	unknown
YLR204W	QRI5______	+1.07	426249	456261	unknown	unknown
YML074C	NPI46_____	-1.31	3444557	2636772	protein folding	peptidyl-prolyl cis-trans isomerase
YMR305C	SCW10_____	+1.04	2218409	2305315	cell wall biogenesis	glucanase (putative)
YNR026C	SEC12_____	-1.22	376370	309577	secretion	ER-to-Golgi GDP/GTP exchange factor
YOR105W	__________	+1.08	372516	400832	unknown	unknown
YPL081W	RPS9A_____	-1.15	11960849	10416458	protein synthesis	ribosomal protein S9A
YPR172W	__________	-1.07	202593	189298	unknown	unknown
YBR153W	RIB7______	-1.05	488373	465099	flavin biosynthesis	HTP reductase
YCR090C	__________	-1.09	555788	509872	unknown	unknown
YDR025W	RPS11A____	+1.06	15743692	16670050	protein synthesis	ribosomal protein S11A
YDR390C	UBA2______	-1.46	562481	386412	protein degradation, ubiquitin-mediated	E1-like (ub.-activating) enzyme
YER087C	SBH1______	+1.00	977635	981586	secretion	ER protein translocation complex subunit
YGL083W	SCY1______	+1.55	222278	343621	unknown	unknown
YGR190C	__________	-1.25	139610	111373	unknown	unknown
YHR207C	__________	-1.06	316776	299001	unknown	unknown
YJL084C	__________	-1.09	317254	291044	unknown	unknown
YKL081W	TEF4______	-1.61	3625936	2249805	protein synthesis	translation elongation factor EF-1gamma
YLR016C	__________	-1.10	291459	264200	unknown	unknown
YLR388W	RPS29A____	+1.00	7503657	7512363	protein synthesis	ribosomal protein S29A
YMR122C	__________	-1.10	237109	216301	unknown	unknown
YNL175C	NOP13_____	-1.31	1597231	1217311	unknown	unknown; nucleolar protein
YOL081W	IRA2______	-1.14	195758	172299	signaling, Ras pathway	GTPase-activating protein for Ras1p and Ras2p
YOR293W	RPS10A____	-1.02	15903873	15616651	protein synthesis	ribosomal protein S10A
YPL269W	KAR9______	-1.17	306173	262626	cytoskeleton	cytoplasmic microtubule orientation
YBL093C	ROX3______	+1.04	269789	279511	transcription	RNA polymerase mediator subunit
YDL095W	PMT1______	-1.12	385299	343087	protein glycosylation	dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
YDR218C	SPR28_____	+1.02	123447	125895	sporulation	septin-related protein
YFR018C	__________	-1.14	157127	137745	unknown	unknown; similar to human glutaminyl-peptide
YGR023W	MTL1______	-1.12	302717	270213	signaling (putative)	unknown; acts with Mid2p
YHR036W	__________	-1.48	508000	342274	unknown	unknown
YIR006C	PAN1______	-1.27	188387	147950	cytoskeleton and endocytosis	actin filament organization
YJR062C	NTA1______	-1.09	121369	111520	protein degradation	amino-terminal amidase
YKR059W	TIF1______	-1.07	12857262	11981082	protein synthesis	translation initiation factor eIF4A
YLR216C	CPR6______	-1.33	944071	708552	protein folding (putative)	peptidyl-prolyl cus-trans isomerase
YMR316W	DIA1______	+1.37	466331	638696	pseudohyphal growth (putative)	unknown
YNR038W	DBP6______	-1.24	471164	381022	rRNA processing	RNA helicase, putative
YOR117W	RPT5______	-1.14	1122755	983735	protein degradation	26S proteasome regulatory subunit
YPL093W	NOG1______	-1.38	938506	677966	unknown	nucleolar G protein
YPR184W	GDB1______	-1.05	130114	123531	glycogen utilization	glycogen debranching enzyme
YBR164C	ARL1______	+1.11	896138	994460	secretion	ADP-ribosylation factor-like protein
YCR101C	__________	-1.02	141419	138277	unknown	unknown; similar to Pep1p, probably represents a fragmented coding region of a pseudogene
YDR035W	ARO3______	-1.14	816665	719036	aromatic amino acid biosynthesis	DAHP synthase
YDR402C	DIT2______	-1.28	151234	118161	sporulation, spore wall biogenesis	synthesizes dityrosine
YER097W	__________	-1.16	130813	112384	unknown	unknown
YGL095C	VPS45_____	+1.16	320715	371244	vacuolar protein targeting	membrane protein
YGR202C	PCT1______	-1.26	353688	280149	phospholipid metabolism	cholinephosphate cytidylyltransferase
YHR216W	IMD2______	-1.44	4329336	3007599	purine biosynthesis	IMP dehydrogenase
YJL096W	MRPL49____	+1.14	547698	625133	protein synthesis	ribosomal protein, mitochondrial L49
YKL093W	MBR1______	-1.52	266728	175492	mitochondrial biogenesis	unknown
YLR028C	ADE16_____	-1.08	450238	416798	purine biosynthesis	5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase
YLR400W	__________	-1.11	376287	338797	unknown	unknown
YMR134W	__________	+1.21	385125	465238	unknown	unknown
YNL187W	__________	-1.09	130242	119350	unknown	unknown
YOL093W	__________	-1.30	614447	474100	unknown	unknown
YOR304W	ISW2______	-1.13	925134	815372	unknown	unknown; similar to Drosophila nucleosome remodeling factor ISW1
YPL281C	ERR2______	-1.40	219458	156908	unknown	unknown; similar to enolase
YAL013W	DEP1______	-1.34	215818	160498	phospholipid metabolism	regulator

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YBR177C	EHT1______	-1.31	245472	187601	unknown	alcohol acyl transferase (putative)
YCRX07W	__________	-1.28	121430	94638
YDR048C	__________	-1.31	100650	77085	unknown	unknown
YDR415C	__________	-1.28	282497	221335	unknown	unknown; similar to bacterial leucyl aminopeptidase
YER110C	KAP123____	-1.86	440812	236379	nuclear protein targeting	beta-karyopherin
YGL108C	__________	+1.07	212981	228260	unknown	unknown
YGR215W	__________	+1.24	337335	419121	unknown	unknown
YIL012W	__________	+1.00	112439	112833	unknown	unknown
YJL109C	__________	-1.21	489530	405811	unknown	unknown
YKL105C	__________	+1.10	181590	199420	unknown	unknown
YLR039C	RIC1______	-1.13	125282	111250	transcription	(putative) transcriptional regulator of rRNA and proteins
YLR411W	CTR3______	-1.05	91624	87192	transport	copper transporter
YMR146C	TIF34_____	-1.18	1957391	1663814	protein synthesis	translation initiation factor eIF3, P39 subunit
YNL200C	__________	+1.13	162387	183138	unknown	unknown
YOL104C	NDJ1______	-1.06	152833	144674	meiosis, chromosome segregation	unknown
YOR316C	COT1______	+1.04	288378	300853	Co2+ ion homeostasis	mitochondrial membrane protein
YPR011C	__________	+1.04	264768	275509	unknown	unknown; similar to human Grave's disease carrier protein
YBL104C	__________	-1.17	250930	213850	unknown	morphology (putative)
YCL011C	GBP2______	+1.17	438464	512163	unknown	telomere-associated protein (putative)
YDL108W	KIN28_____	-1.18	382473	323518	transcription	protein kinase; also TFIIH subunit
YDR231C	COX20_____	-1.21	262908	217631	respiration	req. for cytochrome oxidase assembly
YEL012W	UBC8______	-1.52	208811	137113	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YFR031C	SMC2______	+1.05	14155301	14899735	mitosis, chromosome condensation and segregation	unknown
YGR034W	RPL26B____	+1.02	15342383	15587749	protein synthesis	ribosomal protein L26B
YHR048W	__________	-1.21	235855	195339	unknown	major facilitator superfamily
YIR018W	YAP5______	-1.30	154081	118348	transcription	basic leu zipper transcription factor
YJR075W	HOC1______	-1.25	485285	389682	protein glycosylation	putative mannosyltransferase
YKR072C	SIS2______	+1.02	719592	734785	cell cycle and ion homeostasis	unknown
YML098W	TAF19_____	+1.01	396324	399799	transcription	TFIID 19 kD subunit
YNL012W	SPO1______	-1.02	134503	131402	meiosis (spor.)	transcriptional regulator
YNR051C	BRE5______	-1.52	814925	536872	secretion (putative)	unknown; brefeldin A sensitive
YOR130C	ORT1______	+1.02	255162	259609	arginine biosynthesis	amino acid transporter
YPL106C	SSE1______	-1.36	2173910	1597934	calmodulin signaling	HSP70 family
YPR197C	__________	-1.16	162713	140657	unknown	unknown
YAL025C	MAK16_____	-1.41	831309	590369	dsRNA virus propagation	unknown; essential gene
YBR189W	RPS9B_____	-1.11	11674933	10546152	protein synthesis	ribosomal protein S9B
YCRX19W	__________	-1.28	250933	196705
YDR060W	__________	-1.52	790166	519941	unknown	unknown; similar to human CCAAT-binding protein (GB:Z49209)
YDR427W	RPN9______	+1.14	818905	933128	protein degradation	26S proteasome regulatory subunit
YER121W	__________	-1.26	195344	154970	unknown	unknown
YGL120C	PRP43_____	-1.36	390354	287903	mRNA splicing	spliceosome disassembly factor; RNA helicase
YGR227W	DIE2______	+1.19	149635	178726	glucosylation?	glucosyltransferase
YIL023C	__________	+1.24	293125	364848	unknown	unknown; similar to Atx2
YJL121C	RPE1______	+1.06	1218867	1296660	pentose phosphate cycle	Ribulose-5-phosphate 3-epimerase
YKL117W	SBA1______	+1.05	3394938	3579796	protein folding	Hsp90 associated co-chaperone
YLR051C	__________	+1.09	480288	524671	unknown	unknown
YLR423C	APG17_____	+1.02	153186	155991	unknown	unknown; similar to human cytokeratin 9 (SP:P35527)
YMR157C	__________	-1.05	310955	296034	unknown	unknown
YNL212W	VID27_____	-1.06	435059	409656	vacuolar protein targeting (putative)	unknown
YOL116W	MSN1______	-1.12	256775	229425	nutrient sensing	transcriptional activator
YOR328W	PDR10_____	-1.14	295429	259946	transport	ATP-binding cassette (ABC) family
YPR023C	EAF3______	-1.11	557771	502881	unknown	acetyltrasnferase complex component (putative)
YBR003W	COQ1______	-1.13	259241	229476	ubiquinone biosynthesis	exaprenyl pyrophosphate synthetase
YCL024W	KCC4______	-1.20	111455	93093	bud growth	protein kinase
YDL120W	YFH1______	-1.02	424219	417020	iron homeostasis, mitochondrial	frataxin homolog
YEL023C	__________	-1.02	108142	105748	unknown	unknown
YFR040W	SAP155____	-1.11	475853	427072	cell cycle	Sit4p-associated protein
YGR041W	BUD9______	+1.25	293606	368401	bud site selection, bipolar	unknown
YHR058C	MED6______	+1.07	243437	260893	transcription	RNA polymerase II mediator subunit
YIR028W	DAL4______	+1.21	155984	189196	allantoin utilization	allantoin permease
YJR088C	__________	-1.13	623004	549251	unknown	unknown
YKR084C	HBS1______	+1.01	409654	412341	unknown	unknown; similar to translation elongation factor EF-1alpha
YLR239C	__________	+1.05	253660	267194	unknown	unknown; similar to E. coli LipB protein which is
YML108W	__________	-1.03	371298	360671	unknown	unknown
YNL024C	__________	-1.06	221045	209475	unknown	unknown
YNR063W	__________	-1.03	129766	125527	unknown	unknown; similar to transcription factors, has Zn[2]-Cys[6]
YOR142W	LSC1______	-1.08	634460	589815	TCA cycle	succinyl-CoA ligase alpha subunit
YPL118W	MRP51_____	-1.15	619967	537727	protein synthesis	ribosomal protein, mitochondrial small subunit
YBR201W	DER1______	+1.11	147730	164448	protein degradation, ER	unknown
YDR072C	IPT1______	+1.30	480298	624710	sphingolipid biosynthesis	inositolphosphotransferase 1
YDR439W	LRS4______	+1.02	231091	236745	silencing (rDNA) (putative)	unknown
YER133W	GLC7______	-1.06	903160	849629	glycogen metabolism	protein phosphatase
YGL132W	__________	+1.07	126380	135084	unknown	unknown
YGR239C	PEX21_____	-1.22	288815	237321	peroxisome biogenesis (putative)	unknown, "peroxin"
YIL035C	CKA1______	-1.27	604163	477357	cell cycle (putative)	casein kinase II, catalytic subunit
YJL133W	MRS3______	+1.05	409858	429434	transport	mitochondrial carrier
YKL129C	MYO3______	+1.06	118987	126210	cytoskeleton	myosin, class I
YLR063W	__________	-1.08	119156	110606	unknown	unknown
YLR433C	CNA1______	-1.32	303784	230103	signaling	calcineurin catalytic A subunit
YMR168C	CEP3______	-1.23	288040	235028	mitosis	kinetochore protein complex, 71 KD subunit
YNL224C	__________	+1.01	289829	293520	unknown	unknown
YOL128C	__________	-1.31	224960	171597	unknown	protein kinase
YOR340C	RPA43_____	-1.53	1207520	789352	transcription	RNA polymerase I 36 kD subunit
YPR035W	GLN1______	+1.32	3464143	4564166	glutamine biosynthesis	glutamine synthetase
YBR013C	__________	+1.08	186809	201098	unknown	unknown
YCL036W	__________	-1.29	301916	233754	unknown	unknown
YDL131W	LYS21_____	-1.33	1405840	1057424	lysine biosynthesis	homocitrate synthase
YDR255C	__________	+1.13	157418	177593	unknown	unknown
YEL035C	UTR5______	-1.02	111593	109279	unknown	unknown
YFR052W	RPN12_____	+1.07	801713	854579	protein degradation	26S proteasome regulatory subunit
YGR053C	__________	+1.15	143078	164365	unknown	unknown
YHR069C	RRP4______	-1.04	567233	547456	rRNA processing	3'->5' exoribonuclease
YIR040C	__________	-1.04	136875	131661	unknown	unknown; similar to Yil174p, Yil175p, and Ycr103p, member of
YJR099W	YUH1______	+1.20	290324	349409	protein degradation, ubiquitin-mediated	ubiquitin-specific protease
YKR096W	__________	+1.08	97006	104886	unknown	unknown; similar to aldehyde dehydrogenase
YLR251W	__________	+1.11	145368	162066	unknown	unknown; similar to mouse MPV17 protein
YML119W	__________	-1.03	392912	382466	unknown	unknown
YNR075W	COS10_____	-1.15	117453	102572	unknown	unknown; similar to subtelomerically-encoded proteins
YOR152C	__________	+1.17	208563	243873	unknown	unknown
YPL130W	SPO19_____	-1.06	124829	117226	sporulaiton	GPI-protein, meiosis-specific

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YAL045C	__________	+1.17	259965	305401	unknown	unknown
YBR213W	MET8______	-1.26	152188	120380	sulfate assimilation	siroheme synthase
YDR084C	__________	+1.14	249002	283756	unknown	unknown
YDR451C	__________	+1.07	174800	187892	unknown	unknown; similar to Yox1p, which binds Leu-tRNA (SP:P34161)
YER143W	DDI1______	-1.09	237252	217524	unknown	unknown; induced by DNA damage
YGL144C	__________	+1.00	124928	125444	unknown	unknown
YGR251W	__________	-1.18	342256	289269	unknown	unknown
YIL047C	SYG1______	-1.17	370258	316125	signaling (putative)	pheromone pathway
YJL145W	__________	+1.10	582010	639757	unknown	unknown
YKL141W	SDH3______	+1.40	421632	589931	TCA cycle, oxidative phosphorylation	succinate dehydrogenase cytochrome b
YLR075W	RPL10_____	+1.09	15592273	17020171	protein synthesis	ribosomal protein L10
YLR445W	__________	+1.08	214183	230985	unknown	unknown
YMR178W	__________	-1.04	635306	608841	unknown	unknown
YNL236W	SIN4______	-1.16	364038	313523	transcription	RNA polymerase II mediator subunit
YOL140W	ARG8______	-1.11	195282	175330	arginine biosynthesis	acetylornithine aminotransferase
YOR350C	MNE1______	-1.13	203739	181028	unknown	unknown; similar to Lucilia illustris mitochondria cytochrome oxidase
YPR047W	MSF1______	+1.02	175023	178382	protein synthesis	tRNA synthetase, mitochondrial, phenylalanyl, subunit
YBR025C	__________	-1.62	2844118	1753815	unknown	unknown
YCL048W	__________	-1.17	122718	105091	unknown	unknown; similar to Ecm33p and Sps2p
YDL142C	CRD1______	+1.03	232621	240567	lipid biosynthesis	cardiolipin synthase
YDR263C	DIN7______	-1.26	209298	166585	DNA repair (putative)	DNA damage-inducible
YEL047C	__________	-1.05	357783	341331	unknown	putative fumarate reductase
YGR065C	VHT1______	-1.11	309503	279424	transport	H+-biotin symporter
YHR079C	SAE3______	+1.00	315397	315845	meiosis, recombination	unknown
YJR111C	__________	+1.06	208869	220687	unknown	unknown
YLR260W	LCB5______	+1.00	244789	244857	sphingolipid metabolism	long chain base kinase
YML131W	__________	-1.07	323431	300872	unknown	unknown
YNL046W	__________	+1.13	412324	464712	unknown	unknown
YOR164C	__________	-1.22	835620	685875	unknown	unknown
YPL142C	__________	-1.00	14563226	14535359	unknown	unknown
YAL059W	ECM1______	-1.35	731282	540942	cell wall biogenesis	unknown
YBR225W	__________	+1.00	145362	145747	unknown	unknown
YDR096W	GIS1______	-1.12	154581	137695	unknown	unknown
YDR463W	STP1______	-1.18	283270	239391	tRNA splicing	transcription
YER153C	PET122____	-1.01	105543	104529	protein synthesis	translation activator of COX3
YGL156W	AMS1______	-1.01	187777	185795	cell wall catabolism	vacuolar alpha-mannosidase
YGR263C	__________	+1.01	201712	204150	unknown	unknown
YIL059C	__________	-1.06	226847	214978	unknown	unknown
YJL157C	FAR1______	-1.11	253530	228141	cell cycle	Cdc28p kinase inhibitor
YKL153W	__________	+1.19	15853810	18854180	unknown	unknown
YLR087C	__________	+1.05	192786	202969	unknown	unknown
YLR457C	NBP1______	-1.05	172138	164132	unknown	Nap1p-binding protein
YMR190C	SGS1______	+1.06	121722	129279	mitosis, chromosome segregation	putative DNA helicase
YNL248C	RPA49_____	+1.13	105858	119159	transcription	RNA polymerase I 46 kD subunit
YOL152W	FRE7______	-1.34	294749	220136	unknown	unknown; similar to Fre1p and Fre2p
YOR362C	PRE10_____	-1.03	1287670	1249864	protein degradation	20S proteasome subunit C1 (alpha7)
YPR059C	__________	+1.05	489120	514092	unknown	unknown
YBR037C	SCO1______	-1.24	223198	180424	respiration	Cox1p and Cox2p stability (putative)
YCL060C	__________	-1.06	105625	99416
YDL154W	MSH5______	-1.07	106846	100234	DNA repair	MutS homolog; also recombination
YDR275W	__________	-1.20	310927	258806	unknown	unknown
YGR077C	PEX8______	+1.03	278375	286895	peroxisome biogenesis	unknown
YHR091C	MSR1______	-1.10	372250	339049	protein synthesis	tRNA synthetase, arginyl
YJR123W	RPS5______	+1.06	15577186	16452276	protein synthesis	ribosomal protein S5
YLR271W	__________	-1.45	475051	327854	unknown	unknown; similar to retrovirus-related protease
YMR010W	__________	+1.15	347148	398608	unknown	unknown
YNL056W	__________	+1.14	583281	662993	unknown	unknown
YOR176W	HEM15_____	-1.11	527536	474997	heme biosynthesis	ferrochelatase (protoheme ferrolyase)
YPL154C	PEP4______	+1.28	1207881	1544960	protein degradation	vacuolar aspartyl protease
YAR002W	NUP60_____	-1.04	468315	451527	nuclear protein targeting	nuclear pore protein
YBR237W	PRP5______	-1.08	147507	136483	mRNA splicing	RNA helicase
YDR106W	ARP10_____	+1.05	114206	120047	cytoskeleton (putative)	actin-related protein
YDR475C	__________	-1.03	107872	104256	unknown	unknown
YER163C	__________	+1.18	312671	367623	unknown	unknown
YGL168W	__________	+1.22	617468	750433	unknown	unknown
YGR275W	RTT102____	+1.02	498134	506486	transposition (putative)	unknown; regulator of Ty1 transposition
YIL069C	RPS24B____	+1.06	15339598	16184245	protein synthesis	ribosomal protein S24B
YJL169W	__________	-1.26	617259	488206	unknown	unknown
YKL165C	MCD4______	-1.15	412490	360183	sporulation	morphogenesis checkpoint
YLR099C	ICT1______	-1.03	304310	296050	copper ion homeostasis (putative)	unknown
YNL260C	__________	-1.19	287196	241690	unknown	unknown
YOL164W	__________	-1.13	202946	179789	unknown	unknown; similar to Pseudomonas sp. alkyl sulfatase
YOR374W	ALD4______	+1.18	312669	369783	ethanol utilization	mitochondrial aldehyde dehydrogenase
YPR071W	__________	+1.03	111738	115442	unknown	unknown; similar to Yil029p (GB:Z49219)
YBR049C	REB1______	-1.39	361371	259056	transcription	transcription factor
YCL075W	__________	+1.01	95551	96761	unknown	encoded by Ty5-1
YDL166C	__________	+1.11	726511	805322	unknown	unknown
YDR287W	__________	+1.15	229018	263983	unknown	unknown; similar to inositol monophosphatase (SP:P29218,
YEL070W	__________	+1.01	112722	113841	unknown	unknown; similar to E. coli D-mannonate oxidoreductase
YGR089W	__________	+1.01	211023	212960	unknown	unknown; similar to human desmoplakin I PIR:A35536
YHR103W	SBE22_____	-1.08	186342	172318	bud growth	unknown
YJR135C	MCM22_____	+1.06	214325	228012	mitosis, chromosome segregation	unknown
YLR283W	__________	+1.08	221692	239957	unknown	unknown
YMR022W	QRI8______	+1.26	597504	750554	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YNL068C	FKH2______	-1.23	272158	221711	unknown	unknown; similar to Drosophila forkhead
YOR188W	MSB1______	-1.16	594501	512283	polarized growth	unknown
YPL166W	__________	+1.01	119164	120724	unknown	unknown
YAR027W	__________	+1.25	316231	396864	unknown	unknown; similar to subtelomerically-encoded proteins
YBR249C	ARO4______	-1.09	1619635	1486006	aromatic amino acid biosynthesis	2-dehydro-3-deoxyphosphoheptonate aldolase
YDR118W	APC4______	+1.08	173751	188197	cell cycle	anaphase-promoting complex subunit
YDR487C	RIB3______	+1.21	713053	859502	flavin biosynthesis	3,4-dihydroxy-2-butanone 4-phosphate synthase
YER173W	RAD24_____	-1.05	202705	192420	DNA repair; cell cycle	exonuclease, putative; checkpoint protein
YGL180W	APG1______	-1.01	109272	108357	autophagy	protein kinase
YGR287C	__________	+1.01	169773	171819	unknown	unknown; similar to alpha-D-glucosidase (maltase) (YGR287C
YIL080W	__________	+1.10	288095	316883	unknown	unknown
YJL181W	__________	-1.08	140466	129776	unknown	unknown
YKL177W	__________	-1.20	197535	164505	unknown	unknown
YLR111W	__________	-1.06	123486	116003	unknown	unknown
YMR213W	CEF1______	-1.20	261837	218186	unknown	unknown; similar to S. pombe cdc5+
YNL272C	SEC2______	-1.19	511011	429092	secretion	GDP/GTP exchange factor for Sec4p

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YOR010C	TIR2______	-1.37	612402	445977	unknown	unknown; induced by cold shock
YOR386W	PHR1______	-1.03	146359	142692	DNA repair	deoxyribodipyrimidine photolyase
YPR083W	__________	-1.10	204811	186653	unknown	unknown; similar to Halobacterium holobium cell surface
YBR061C	__________	-1.22	505545	415650	unknown	unknown; similar to Ctr86p and E. coli ftsJ
YCLX11W	__________	-1.29	718761	559182
YDL178W	AIP2______	+1.00	535507	536144	unknown	actin interacting protein
YDR299W	BFR2______	-1.27	544223	430118	secretion	unknown
YER004W	__________	-1.02	862099	846030	unknown	unknown
YGR101W	__________	+1.04	191088	198524	unknown	unknown
YHR115C	__________	+1.08	565005	607576	unknown	unknown
YJR147W	HMS2______	-1.43	326799	229073	pseudohyphal growth	transcription factor
YLR294C	__________	+1.37	552068	758816	unknown	unknown
YNL080C	__________	+1.01	308465	311201	unknown	unknown
YOR198C	BFR1______	-1.06	1296231	1217589	secretion	unknown
YPL178W	CBC2______	-1.05	1013583	967921	meiosis, recombination	nuclear cap-binding protein complex small subunit
YAR047C	__________	-1.07	112426	105021	unknown	unknown
YBR261C	__________	-1.26	483431	382642	unknown	unknown
YDR130C	FIN1______	+1.10	226600	248347	cell cycle (putative)	intermediate filament protein
YDR499W	LCD1______	-1.09	199066	182473	unknown	unknown
YER185W	__________	+1.10	126816	139078	unknown	unknown; similar to Rtm1p
YGL192W	IME4______	-1.05	144873	138134	meiosis	transcription factor
YIL091C	__________	-1.18	514289	435960	unknown	unknown
YJL193W	__________	-1.04	272938	263697	unknown	unknown; similar to Sly41p and to triose
YKL189W	HYM1______	+1.01	208095	210427	unknown	unknown; similar to Aspergillus nidulans hymA which is
YLR123C	__________	+1.02	104113	106480	unknown	unknown; similar to class I family of aminoacyl-tRNA
YMR224C	MRE11_____	-1.00	167269	166823	meiosis, recombination	ds break formation complex subunit
YNL284C	MRPL10____	-1.00	469875	469140	protein synthesis	ribosomal protein, mitochondrial L10
YOR022C	__________	+1.05	146185	153524	unknown	unknown
YPR095C	SYT1______	+1.14	111409	127185	unknown	unknown; similar to S. typhimurium T1pA alpha-helical
YBR073W	RDH54_____	-1.04	357780	345094	meiosis	helicase
YCR011C	ADP1______	+1.07	317403	339490	transport	(putative) ATP-dependent permease
YDL190C	UFD2______	-1.13	251201	221471	protein degradation, ubiquitin-mediated	unknown; may influence multi-Ub chain topology
YDR311W	TFB1______	-1.10	254553	230435	transcription	TFIIH 75 kD subunit
YER014W	HEM14_____	+1.05	175075	184433	heme biosynthesis	protoporphyrinogen oxidase
YGR111W	__________	+1.13	398483	448819	unknown	unknown; similar to southern house mosquito carboxylesterase
YHR127W	HSN1______	-1.08	631083	586038	unknown	suppresses SEC4 dominant negative mutant
YJR159W	SOR1______	+1.07	200286	214565	sorbitol metabolism	sorbitol dehydrogenase
YLR306W	UBC12_____	-1.00	145409	145379	protein degradation, ubiquitin-mediated	E2 ub.-conjugating enzyme
YNL092W	__________	-1.01	123222	121694	unknown	unknown
YOR210W	RPB10_____	-1.39	824230	593754	transcription	shared subunit of RNA polymerases I, II, and III
YPL189W	GUP2______	+1.05	121610	127628	glycerol utilization	glycerol transporter (putative)
YBL010C	__________	-1.31	218235	166890	unknown	unknown
YBR273C	__________	-1.38	363038	263590	unknown	unknown
YDL012C	__________	-1.51	320333	212180	unknown	unknown
YDR142C	PEX7______	-1.36	182007	133622	peroxisome biogenesis	import receptor
YDR511W	__________	+1.11	235174	262044	unknown	unknown
YFL010W	AUA1______	+1.01	929486	941531	amino acid uptake	ammonia regulation of GAP1 activity
YGL204C	__________	-1.19	358003	300493	unknown	unknown
YIL102C	__________	-1.03	122840	119455	unknown	unknown
YJL205C	NCE101____	+1.17	214978	252593	secretion, non-classical	unknown
YKL201C	MNN4______	-1.02	100016	97769	protein glycosylation	phosphatidylinositol kinase homolg
YLR135W	__________	+1.08	124436	133971	unknown	unknown
YML010W	SPT5______	-1.27	387466	304019	transcription	elongation factor
YMR237W	__________	+1.09	384026	417057	unknown	unknown; similar to Chs6p/Csd3p
YNL294C	__________	+1.32	293121	385606	unknown	unknown
YOR034C	AKR2______	-1.13	220374	194739	endocytosis of Ste3p	unknown
YPL012W	__________	-1.19	1209694	1018790	unknown	unknown
YPR107C	YTH1______	+1.20	294715	352676	mRNA 3'-end processing	cleavage/polyadenylation specificity factor subunit
YBR084W	MIS1______	-1.64	786735	478585	folate metabolism	C1-tetrahydrofolate synthase
YCR022C	__________	-1.35	133676	99344	unknown	unknown
YDL202W	MRPL11____	-1.05	203985	193954	protein synthesis	ribosomal protein, mitochondrial L11
YDR321W	ASP1______	-1.48	1423615	962536	asparagine utilization	L-asparaginase I
YER024W	__________	-1.22	210977	173292	unknown	unknown; similar to Yat1p
YGL012W	ERG4______	-1.13	1039811	916933	sterol metabolism	sterol C-24 reductase
YGR123C	PPT1______	-1.18	636126	537680	unknown	protein phosphatase
YHR138C	__________	+1.52	207102	315388	unknown	unknown
YJL012C	PHM3______	-1.21	700916	577354	phosphate metabolism (putative)	polyphosphate synthetase (putative)
YKL011C	CCE1______	+1.09	218460	238097	tRNA processing	cruciform cutting endonuclease
YLL012W	__________	+1.04	417869	434281	unknown	unknown; similar to human triacylglycerol lipase
YLR317W	__________	-1.02	120839	118136	unknown	unknown
YMR054W	STV1______	-1.02	209682	205657	vacuolar acidification	vacuolar H+-ATPase V0 domain 102 KD subunit
YNL104C	LEU4______	-1.09	812008	741899	leucine biosynthesis	2-isopropylmalalate synthase
YOL012C	HTA3______	+1.03	820166	846443	chromatin structure	histone-related
YOR222W	ODC2______	+1.27	303601	386977	unknown	unknown; similar to mitochondrial ADP/ATP carrier proteins
YPL201C	__________	+1.09	135847	147646	unknown	unknown
YAR071W	PHO11_____	+1.75	1242491	2174343	phosphate metabolism	secreted acid phosphatase
YBL022C	PIM1______	-1.34	274426	205286	respiration	mitochondrial ATP-dependent protease
YBR285W	__________	-1.12	100029	89375	unknown	unknown
YDL024C	DIA3______	-1.04	112026	108209	pseudohyphal growth (putative)	unknown
YDR154C	__________	+1.11	5551932	6177153	unknown	unknown
YDR523C	SPS1______	-1.03	154915	151007	meiosis	protein kinase
YFL018C	LPD1______	-1.32	226787	171436	TCA cycle	dihydrolipoamide dehydrogenase
YGL216W	KIP3______	-1.08	152536	140735	mitosis	kinesin related protein
YHL020C	OPI1______	+1.07	1031241	1106132	phospholipid metabolism	negative regulator of phospholipid biosynthesis
YIL114C	POR2______	+1.00	167475	167566	mitochondrial transport	porin, anion channel
YJL217W	__________	-1.09	1564244	1434761	unknown	unknown
YKL213C	DOA1______	+1.02	345711	351833	protein degradation, ubiquitin-mediated	unknown
YLR147C	SMD3______	+1.06	255334	270415	mRNA splicing	core snRNP protein
YML021C	UNG1______	-1.07	351361	327371	DNA repair	uracil DNA glycosylase
YMR250W	GAD1______	+1.14	152334	173672	glutamate metabolism	glutamate decarboxylase
YNL306W	__________	-1.14	243873	213139	protein synthesis	ribosomal protein, mitochondrial small subunit
YOR046C	DBP5______	-1.15	1547153	1344593	mRNA export	RNA helicase
YPL024W	NCE4______	+1.07	290695	310162	cell separation	negative regulator of CTS1 expression
YPR119W	CLB2______	-1.03	222883	215754	cell cycle	G2/M cyclin
YBR095C	__________	-1.08	208287	192780	unknown	unknown; similar to Drosophila cyclin B
YCR032W	BPH1______	+1.04	280540	291442	transport	acetic acid export pump (putative)
YDL214C	__________	-1.08	97660	90548	unknown	protein kinase
YDR333C	__________	-1.21	327814	270006	unknown	unknown
YER036C	__________	-1.41	960596	681318	unknown	unknown; similar to members of the ATP-binding cassette
YGL024W	__________	-1.26	114735	91011	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YGR135W	PRE9______	+1.07	1213275	1295948	protein degradation	20S proteasome subunit Y13 (alpha3)
YHR148W	IMP3______	-1.12	533397	474691	rRNA processing	U3 snoRNP protein
YJL024C	APS3______	-1.21	289818	239806	vacuolar protein targeting	AP-3 complex subunit
YKL023W	__________	+1.06	269874	286012	unknown	unknown
YLL024C	SSA2______	-2.34	3096642	1324785	ER and mitochondrial translocation	cytosolic HSP70
YLR329W	REC102____	-1.05	139524	132644	meiosis, recombination	ds break formation complex subunit
YMR066W	SOV1______	+1.21	134921	162591	respiration (putative)	unknown; synthesis of Var
YNL116W	__________	-1.23	581715	472313	unknown	unknown
YOL024W	__________	-1.10	153245	139183	unknown	unknown
YOR234C	RPL33B____	-1.03	7188844	7005436	protein synthesis	ribosomal protein L33B
YPL213W	LEA1______	+1.13	375293	423255	mRNA splicing	U2 snRNP protein
YBL034C	STU1______	-1.12	152517	136180	mitosis	spindle component
YBR297W	MAL33_____	-1.07	149291	140109	maltose metabolism	regulator of maltose metabolic genes
YDL036C	__________	-1.24	289474	233077	unknown	unknown; similar to Rib2p
YDR166C	SEC5______	-1.00	89869	89493	secretion	exocyst complex subunit
YDR535C	__________	+1.01	101108	102604	unknown	unknown
YFL029C	CAK1______	+1.03	266472	273504	cell cycle	protein kinase
YGL227W	VID30_____	+1.06	650067	687116	vacuolar protein targeting (putative)	unknown; TOR inhibitor
YHL031C	GOS1______	-1.00	337584	336515	secretion	Golgi SNARE
YIL126W	STH1______	+1.01	99615	100404	chromatin structure	chromatin remodeling complex subunit
YJR005W	APL1______	-1.09	225318	205827	secretion	vesicle coat component
YKL225W	__________	+1.10	94743	104493	unknown	unknown
YML032C	RAD52_____	-1.22	245351	200973	DNA repair and recombination	Rad51p cofactor
YMR261C	TPS3______	-1.06	304668	287371	trehalose utilization	alpha,alpha-trehalose-phosphate synthase
YNL318C	HXT14_____	-1.07	112410	105264	transport	hexose permease
YOR058C	ASE1______	-1.12	286279	256068	mitosis	spindle midzone component
YPL036W	PMA2______	-1.81	448089	248195	H+ homeostasis	plasma membrane H+-ATPase
YPR131C	NAT3______	+1.08	330270	357187	protein processing	protein N-acetyltransferase
YBR107C	IML3______	+1.10	165123	182441	mitosis, chromosome segregation (putative)	unknown
YCR044C	PER1______	+1.08	339314	367076	protein processing (putative)	unknown
YDL226C	GCS1______	-1.09	710638	650270	secretion	vesicle transport; GAP for ARF
YDR345C	HXT3______	-1.13	3868216	3427148	transport	hexose permease
YER046W	__________	+1.05	239761	252740	unknown	unknown
YGL036W	MTC2______	+1.08	675920	729101	unknown	unknown
YGR147C	NAT2______	+1.04	242873	253312	protein processing	N-acetyltransferase for N-terminal methionine
YHR160C	PEX18_____	+1.07	140340	149828	peroxisome biogenesis (putative)	unknown, "peroxin"
YJL036W	SNX4______	+1.21	233472	281561	protein targeting (putative)	unknown; similar to human sorting nexins
YKL034W	__________	-1.03	193170	187437	unknown	unknown
YLL036C	PRP19_____	-1.12	282160	252807	mRNA splicing; DNA repair	non-snRNP spliceosome component
YLR341W	__________	+1.12	118101	132156	unknown	unknown
YMR077C	__________	-1.09	257555	236169	unknown	unknown; similar to Snf7p
YNL128W	TEP1______	-1.16	217106	186512	unknown	protein phosphatase
YOL036W	__________	-1.13	388760	343240	unknown	unknown
YOR246C	__________	-1.20	583782	485528	unknown	unknown
YPL225W	__________	-1.00	1427346	1423094	unknown	unknown
YBL046W	__________	-1.13	242333	214030	unknown	unknown
YDL048C	STP4______	+1.50	281274	422153	tRNA splicing	unknown
YDR176W	NGG1______	-1.03	151449	146807	chromatin structure	histone acetyltransferase complex subunit
YFL039C	ACT1______	-1.01	5514431	5466934	cytoskeleton	actin
YGL239C	__________	-1.01	175550	173462	unknown	unknown
YHL043W	ECM34_____	-1.02	160369	157881	cell wall biogenesis	unknown
YIL138C	TPM2______	-1.00	313618	312545	cytoskeleton	tropomyosin
YJR016C	ILV3______	-1.63	1243254	764449	isoleucine and valine biosynthesis	dihydroxyacid dehydratase
YKR012C	__________	-1.25	196352	157301	unknown	unknown
YLR169W	__________	+1.17	87987	102941	unknown	unknown
YML042W	CAT2______	-1.10	121688	111112	fatty acid transport	carnitine O-acetyltransferase
YNL330C	RPD3______	-1.26	526925	417639	chromatin structure	histone deacetylase
YOR070C	GYP1______	-1.10	132153	120324	signaling	GTPase-activating protein for Ypt1p
YPL048W	CAM1______	-1.52	2520357	1652797	protein synthesis	translation elongation factor EF-1gamma
YPR141C	KAR3______	-1.08	373011	344275	mating; nuclear fusion; mitosis	kinesin-like protein
YBR118W	TEF2______	+1.20	15752962	18866298	protein synthesis	translation elongation factor EF-1 alpha
YCR056W	__________	-1.48	1275171	858796
YDL238C	__________	-1.54	1484209	965384	unknown	unknown
YDR357C	__________	-1.22	697356	573706	unknown	unknown
YER056C	RPL34A____	-1.29	1564408	1213995	protein synthesis	ribosomal protein L34A
YGL048C	RPT6______	-1.26	699172	554101	protein degradation	26S proteasome regulatory subunit
YGR159C	NSR1______	-1.39	2926835	2109014	nuclear protein targeting	NLS-binding protein
YHR172W	SPC97_____	-1.11	228131	206248	cytoskeleton	spindle pole body component
YJL049W	__________	+1.00	332810	332981	unknown	unknown
YKL046C	__________	-1.06	500785	472325	unknown	unknown
YLL048C	YBT1______	+1.06	139693	148498	transport	bile acid transporter of ABC family
YLR353W	BUD8______	-1.05	122632	117238	bud site selection, bipolar	unknown
YMR088C	__________	-1.10	294791	269064	unknown	unknown
YNL140C	__________	-1.06	330063	310176	unknown	unknown
YOL048C	__________	+1.36	179197	243559	unknown	unknown
YOR258W	__________	+1.06	218820	231158	unknown	unknown
YPL237W	SUI3______	-1.19	1219984	1025303	protein synthesis	translation initiation factor eIF2 beta subunit
YBL058W	SHP1______	-1.04	462128	444449	glucose repression	(putative) Glc7p regulatory subunit
YDL060W	__________	-1.29	190497	148057	unknown	unknown
YDR187C	__________	-1.80	181369	100623	unknown	unknown
YFL051C	__________	-1.07	104004	97362	unknown	unknown; similar to Flo1p family of proteins
YGL251C	HFM1______	-1.12	212422	189204	unknown	DNA/RNA helicase, putative
YHR003C	__________	-1.52	738199	485347	unknown	unknown; similar to Ykl027p and weak similarity to E.
YIL150C	DNA43_____	-1.40	341813	243381	DNA replication	unknown
YJR027W	__________	+1.20	15958128	19070804	unknown	unknown; similar to E. coli molybdopterin-converting factor
YKR024C	DBP7______	-1.48	1519725	1027767	ribosome biogenesis	putative RNA helicase
YLR181C	__________	+1.07	523652	557824	unknown	unknown
YMR285C	__________	-1.16	396542	340648	unknown	unknown
YNR003C	RPC34_____	-1.52	395899	259901	transcription	RNA polymerase III 34 kD subunit
YOR082C	__________	-1.28	329327	256885	unknown	unknown
YPR153W	__________	-1.10	120148	109466	unknown	unknown
YBR130C	SHE3______	-1.03	270358	262160	cell polarity	asymmetric HO expression
YCR068W	__________	-1.00	117449	116942	unknown	unknown
YDR002W	YRB1______	+1.03	3130360	3231886	nuclear protein targeting	GTPase-activating protein for Ran
YDR367W	__________	+1.09	387159	422461	unknown	unknown
YGL060W	__________	+1.03	239546	246722	unknown	unknown
YGR167W	CLC1______	+1.12	1598950	1784977	endocytosis and secretion	clathrin light chain
YHR184W	SSP1______	-1.03	313464	304841	meiosis,nuclear division and spore formation	unknown
YJL061W	NUP82_____	-1.25	586177	467448	nuclear protein targeting	nuclear pore protein
YKL058W	TOA2______	+1.23	506874	623940	transcription	TFIIA 13.5 kD subunit

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YLL060C	GTT2______	-1.09	295465	271538	glutathione metabolism	glutathione transferase
YLR365W	__________	-1.04	114562	110270	unknown	unknown
YMR100W	MUB1______	-1.18	246411	208094	bud site selection	unknown
YNL152W	__________	-1.26	280980	222140	unknown	unknown
YOL058W	ARG1______	-1.00	399314	398501	arginine biosynthesis	arginosuccinate synthetase
YOR270C	VPH1______	-1.10	1991509	1815488	vacuolar acidification	vacuolar H+-ATPase 95 kD subunit
YPL249C	__________	-1.18	143596	121776	unknown	unknown
YBL070C	__________	+1.07	87714	94086	unknown	unknown
YDL072C	__________	+1.77	646705	1142775	unknown	unknown
YDR199W	__________	+1.41	193577	273342	unknown	unknown
YFL063W	__________	+1.22	121643	148089	unknown	unknown; similar to Gin11p and Ykl225p
YGL263W	COS12_____	+1.25	158372	197421	unknown	unknown; similar to subtelomerically-encoded proteins
YHR014W	SPO13_____	+1.09	122665	134184	meiosis	negative regulator of M phase (putative)
YIL161W	__________	+1.06	305921	324929	unknown	unknown
YJR039W	__________	+1.05	164628	173617	unknown	unknown; similar to Paramecium tetraurelia NADH
YKR036C	CAF4______	+1.04	256678	265811	catabolite repression	component of CCR4 transcriptional complex
YLR193C	__________	+1.01	289602	293473	unknown	unknown; similar to Msf1p
YML063W	RPS1B_____	+1.24	15410630	19164411	protein synthesis	ribosomal protein S1B
YMR295C	__________	+1.29	1161470	1503236	unknown	unknown
YNR015W	SMM1______	-1.30	652552	500889	protein synthesis, mitochondrial (putative)	unknown
YOR094W	ARF3______	-1.01	469899	467162	secretion	GTP-binding ADP-ribosylation factor
YPL070W	__________	+1.05	396806	415715	unknown	unknown
YPR161C	SGV1______	-1.23	451763	367765	cell cycle	protein kinase
YBR142W	MAK5______	-1.31	272197	207063	mRNA splicing	RNA helicase
YCR080W	__________	+1.01	87750	88239
YDR014W	__________	-1.06	106576	100216	unknown	unknown
YDR379W	RGA2______	-1.01	113313	112456	signaling	Rho-GTPase activating protein
YER076C	__________	+1.02	127441	130012	unknown	unknown; similar to KHR1 killer toxin
YGL072C	__________	+1.18	238492	281875	unknown	unknown
YGR179C	__________	+1.05	262428	275371	unknown	unknown; similar to chicken myosin heavy chain, cardiac
YHR196W	__________	-1.12	729297	652405	unknown	unknown
YJL073W	JEM1______	+1.06	375992	398379	mating; nuclear fusion	DnaJ-like protein
YKL070W	__________	+1.04	121364	126115	unknown	unknown; similar to Bacillus subtilis transcriptional
YLR005W	SSL1______	-1.02	446954	439442	transcription	TFIIH subunit
YLR377C	FBP1______	+1.09	144887	157669	gluconeogenesis	fructose-1,6-bisphosphatase
YMR112C	MED11_____	+1.07	273017	293310	transcription	RNA polymerase II mediator subunit
YNL164C	__________	-1.22	276607	227547	unknown	unknown
YOL070C	__________	-1.06	484412	455450	unknown	unknown
YOR282W	__________	-1.33	184301	138499	unknown	unknown
YPL258C	THI21_____	-1.05	174936	167016	thiamine metabolism (putative)	unknown
YBL082C	RHK1______	-1.25	465108	372046	protein glycosylation	Dol-P-Man dependent alpha-1,3- mannosyltransferase (putative)
YDL084W	SUB2______	-1.09	3193468	2937768	mRNA splicing	RNA helicase
YFR007W	__________	-1.06	121268	114540	unknown	unknown
YGR012W	__________	-1.07	500946	468978	unknown	unknown; similar to Cys4p
YHR025W	THR1______	-1.20	1424366	1185479	threonine biosynthesis	homoserine kinase
YIL172C	__________	-1.13	206598	183439	unknown	unknown; similar to alpha-D-glucosidase (maltase)
YJR051W	OSM1______	+1.06	423710	449521	anaerobic growth (putative)	fumarate reductase
YKR048C	NAP1______	-1.16	1003273	867079	chromatin structure	nucleosome assembly protein
YLR205C	__________	+1.42	222155	314952	unknown	unknown
YML075C	HMG1______	-1.35	1520788	1128094	sterol metabolism	3-hydroxy-3-methylglutaryl-coenzyme A reductase
YMR306W	FKS3______	-1.12	347966	310908	unknown	unknown; similar to Gls1p and Gls2p
YNR027W	__________	-1.24	269214	216258	unknown	unknown
YOR106W	VAM3______	-1.10	396530	360334	vacuole biogenesis	t-SNARE
YPL082C	MOT1______	+1.09	330345	359440	transcription	putative helicase
YPR173C	VPS4______	-1.14	859034	753197	vacuolar protein targeting	AAA ATPase family
YBR154C	RPB5______	-1.02	1046458	1023581	transcription	shared subunit of RNA polymerases I, II, and III
YCR091W	KIN82_____	-1.00	127618	127032	unknown	protein kinase
YDR026C	__________	-1.05	154096	146457	unknown	unknown; similar to Reb1p
YDR391C	__________	+1.50	217502	326463	unknown	unknown
YER087W	__________	+1.07	161542	172638	unknown	unknown; similar to E. coli prolyl-tRNA synthetase
YGL084C	GUP1______	+1.04	270174	281205	glycerol utilization	glycerol transporter (putative)
YGR191W	HIP1______	-1.31	642261	491284	transport	histidine permease
YHR208W	BAT1______	-1.29	1540986	1192761	branched chain amino acid degradation	transaminase
YJL085W	EXO70_____	-1.16	367193	315268	secretion	exocyst complex subunit
YKL082C	__________	-1.06	1123914	1063301	unknown	unknown
YLR017W	MEU1______	-1.18	819950	692984	glucose derepression	regulator of ADH2 expression
YLR389C	STE23_____	-1.16	253995	218099	mating	a-factor processing protease (putative)
YMR123W	PKR1______	-1.08	657107	610757	killer toxin sensitivity (Pichia farinosa toxin)	unknown
YNL176C	__________	+1.06	240479	253876	unknown	unknown
YOL082W	__________	+1.35	215945	292600	unknown	unknown
YOR294W	RRS1______	-1.19	1112624	938191	ribosome biogenesis (putative)	unknown
YPL270W	MDL2______	+1.13	310170	351330	transport	ATP-binding cassette (ABC) family
YBL094C	__________	+1.36	217496	296254	unknown	unknown; similar to Neurospora crassa chitin synthase
YDL096C	__________	-1.24	122460	98571	unknown	unknown
YDR219C	__________	+1.01	212500	214463	unknown	unknown
YFR019W	FAB1______	+1.00	101964	102154	mitosis	putative PIP 5-kinase
YGR024C	__________	+1.21	625632	757481	unknown	unknown
YHR037W	PUT2______	-1.21	192483	158756	amino acid biosynthesis	delta-1-pyrroline-5-carboxylate dehydrogenase
YIR007W	__________	-1.05	165204	157297	unknown	unknown; similar to endoglucanase
YJR063W	RPA12_____	+1.00	864632	864707	transcription	RNA polymerase I subunit
YKR060W	__________	-1.01	502770	497305	unknown	unknown
YLR217W	__________	-1.31	176447	134570	unknown	unknown
YML087C	__________	+1.15	224933	259199	unknown	unknown
YNR039C	ZRG17_____	-1.05	334044	317499	unknown	unknown; similar to Anopheles mitochondrial NADH
YOR118W	__________	-1.06	116238	109480	unknown	unknown
YPL094C	SEC62_____	-1.04	1313591	1264191	secretion	ER protein translocation subcomplex subunit
YPR185W	APG13_____	+1.09	1080672	1173691	autophagy	unknown
YBR165W	UBS1______	+1.12	120819	135238	protein degradation, ubiquitin-mediated	regulates Cdc34p (ubiquitin-conjugating enzyme)
YCR102C	__________	+1.12	125531	140595	unknown	unknown; similar to Bacillus subtilis sorbitol
YDR036C	__________	-1.09	209379	191244	unknown	unknown; similar to enoyl CoA hydratase
YDR403W	DIT1______	+1.07	113768	122193	sporulation, spore wall biogenesis	synthesizes dityrosine precursor
YER098W	UBP9______	-1.01	153869	152235	protein degradation, ubiquitin-mediated	ubiquitin C-terminal hydrolase
YGL096W	__________	+1.05	102551	107591	unknown	unknown; similar to Cup9p
YGR203W	__________	-1.28	671971	525356	unknown	unknown
YHR217C	__________	-1.02	655202	644754	unknown	unknown
YJL097W	__________	+1.24	843175	1047616	unknown	unknown
YKL094W	YJU3______	+1.05	566268	592663	unknown	unknown; similar to E.coli hypothetical protein
YLR029C	RPL15A____	+1.20	15807570	19021874	protein synthesis	ribosomal protein L15A
YLR401C	__________	-1.37	422638	309003	unknown	unknown; similar to R. capsulatus protein nifR3
YMR135C	__________	-1.07	304950	285118	unknown	unknown

		factor	median_fitted_data	median_fitted_data	gene annotation	gene annotation
		condition1	condition0(CONTROL)	condition1	functional category	description
		delta knr4	wt, strain AR27	delta knr4


YNL188W	KAR1______	-1.03	346466	335651	cytoskeleton	nuclear fusion; also spindle
YOL094C	RFC4______	-1.18	553758	470363	DNA replication	replication factor C, 37 kDa subunit
YPL282C	__________	-1.05	97381	92654	unknown	unknown; similar to other subtelomerically-encoded proteins