Publications
Albrecht, SC, Gomes
Barata, A, Grosshans, J, Teleman, AA & Dick,
TP (2011): In vivo mapping of
hydrogen peroxide and oxidized glutathione reveals chemical and regional
specificity of redox homeostasis. Cell
Metab in press, doi:10.1016/j.cmet.2011.10.010
Morgan B, Sobotta M, and
Dick TP (2011) Measuring EGSH and H2O2
with roGFP2-based redox probes. Free Radic Biol Med. (in press)
Engelhard, J., Christian, B.E., Weingarten, L., Kuntz, G., Spremulli, L.L., and Dick T.P. (2011). In situ kinetic trapping reveals a fingerprint of reversible protein thiol oxidation in the mitochondrial matrix. Free Radic Biol Med 50, 1234-1241.
Braun, N. A., Morgan, B., Dick, T. P., and Schwappach, B. (2010). The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci 123, 2342-2350.
Meyer, A. J., and Dick, T. P. (2010). Fluorescent Protein-based Redox Probes. Antioxid Redox Signal 13, 621-650.
Reth, M. and Dick, T. P. (2010). Voltage control for B cell activation. Nat Immunol 11, 191-192.
Gutscher, M., Sobotta,M., Wabnitz, G., Ballikaya, S., Meyer, A., Samstag, Y., and Dick, T. P. (2009). Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases. J Biol Chem 284, 31532-31540. (JBC paper of the week)
Gutscher, M., Pauleau, A., Brach, T., Marty, L., Wabnitz, G., Samstag, Y., Meyer A. J., and Dick, T. P. (2008). Real-time imaging of the intracellular glutathione redox potential. Nat Meth 5, 553-559. (Selected by Faculty of 1000)
Schwertassek, U., Weingarten, L., Dick, T. P. (2007). Analysis of cell surface redox processes by mechanism-based kinetic trapping. Sci STKE 2007, pl8.
Kienast, A., Preuss, M., Winkler, M., and Dick, T. P. (2007). Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin. Nat Immunol 8, 864-872. (with News & Views; Selected by Faculty of 1000)
Schwertassek, U., Balmer, Y., Gutscher, M., Weingarten, L., Preuss, M., Engelhard, J., Winkler, M., and Dick, T. P. (2007). Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1. EMBO J 26, 3086-3097. (Selected by Faculty of 1000; Science's STKE Editor's Choice)
Schwertassek, U. and Dick, T.P. (2006) Activity-based proteomics. BIOforum 6, 46-47.
Dick, T. P. (2004) Assembly of MHC class I peptide complexes from the perspective of disulfide bond formation. Cell Mol Life Sci 61, 547-556.
Dick, T. P., Bangia, N., Peaper, D., and Cresswell, P. (2002). Disulfide bond isomerization and the assembly of MHC class I-peptide complexes. Immunity 16, 87-98.
Dick, T. P., and Cresswell, P. (2002). Thiol oxidation and reduction in MHC class I-restricted antigen processing and presentation. Methods Enzymol 348, 49-54.
Phan, U. T., Maric, M., Dick, T. P., and Cresswell, P. (2001). Multiple species express thiol oxidoreductases related to GILT. Immunogenetics 53, 342-6.
Toes, R. E., Nussbaum, A. K., Degermann, S., Schirle, M., Emmerich, N. P., Kraft, M., Laplace, C., Zwinderman, A., Dick, T. P., Muller, J., Schonfisch, B., Schmid, C., Fehling, H. J., Stevanovic, S., Rammensee, H. G., and Schild, H. (2001). Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products. J Exp Med 194, 1-12.
Kuttler, C., Nussbaum, A. K., Dick, T. P., Rammensee, H. G., Schild, H., and Hadeler, K. P. (2000). An algorithm for the prediction of proteasomal cleavages. J Mol Biol 298, 417-29.
Cresswell, P., Arunachalam, B., Bangia, N., Dick, T., Diedrich, G., Hughes, E., and Maric, M. (1999). Thiol oxidation and reduction in MHC-restricted antigen processing and presentation. Immunol Res 19, 191-200.
Cresswell, P., Bangia, N., Dick, T., and Diedrich, G. (1999). The nature of the MHC class I peptide loading complex. Immunol Rev 172, 21-8.
Dick, T. P., Nussbaum, A. K., Deeg, M., Heinemeyer, W., Groll, M., Schirle, M., Keilholz, W., Stevanovic, S., Wolf, D. H., Huber, R., Rammensee, H. G., and Schild, H. (1998). Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants. J Biol Chem 273, 25637-46.
Dick, T. P., Nussbaum, A. K., Keilholz, W., Schirle, M., Stevanovic, S., Dietz, K., Heinemeyer, W., Groll, M., Wolf, D. H., Huber, R., Rammensee, H. G., and Schild, H. (1998). Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. Proc Natl Acad Sci U S A 95, 12504-9. (the first two authors contributed equally)
Dick, T. P., Stevanovic, S., Keilholz, W., Ruppert, T., Koszinowski, U., Schild, H., and Rammensee, H. G. (1998). The making of the dominant MHC class I ligand SYFPEITHI. Eur J Immunol 28, 2478-86.
Stoltze, L., Dick, T. P., Deeg, M., Pommerl, B., Rammensee, H. G., and Schild, H. (1998). Generation of the vesicular stomatitis virus nucleoprotein cytotoxic T lymphocyte epitope requires proteasome-dependent and -independent proteolytic activities. Eur J Immunol 28, 4029-36.
Groettrup, M., Soza, A., Eggers, M., Kuehn, L., Dick, T. P., Schild, H., Rammensee, H. G., Koszinowski, U. H., and Kloetzel, P. M. (1996). A role for the proteasome regulator PA28alpha in antigen presentation. Nature 381, 166-8.
Schamel, W. W., and Dick, T. P. (1996). Signal transduction: specificity of growth factors explained by parallel distributed processing. Med Hypotheses 47, 249-55.
Dick, T. P., Ruppert, T., Groettrup, M., Kloetzel, P. M., Kuehn, L., Koszinowski, U. H., Stevanovic, S., Schild, H., and Rammensee, H. G. (1996). Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands. Cell 86, 253-62.
Dick, T. P., and Schamel, W. A. (1995). Molecular evolution of transfer RNA from two precursor hairpins: implications for the origin of protein synthesis. J Mol Evol 41, 1-9.
Weimbs, T., Dick, T., Stoffel, W., and Boltshauser, E. (1990). A point mutation at the X-chromosomal proteolipid protein locus in Pelizaeus-Merzbacher disease leads to disruption of myelinogenesis. Biol Chem Hoppe Seyler 371, 1175-83.