Head: Anika Jöcker
Members: Jitao Zhang, Christian Bender, Dirk Ledwinka, Bastian Buchholz
Former Members: Tim Beißbarth, Florian Hahne, Markus Seiler, Heiko Rosenfelder, Markus Ruschhaupt, Andreas Buness, Alexander Mehrle, Michael Weidlich, Jörg Kunert, Achim Tresch, Holger Fröhlich, Wolfgang Huber

The Bioinformatics and Modeling Group is a core element of the division and fulfills multiple tasks. These cover the statistical support in the planning of experiments, system administration and maintenance of a laboratory information management system (LIMS), implementation of tools, interfaces and databases, bioinformatics prediction of gene functions and pathways, data analysis and visualization, and the functional interpretation of data in discussions between data modelers and experimentalists. However, our work extends further into scientific questions in Bioinformatics, Biostatistics, and theoretical Systems Biology that are addressed to develop improved methods and tools for data analysis and interpretation. A special focus of the division is the functional interpretation of high-throughput data and the reconstruction of cellular pathways. State-of-the-art data analysis is applied in relevant biomedical projects, driving internationally competitive and respected bioinformatics method development. Also this work has substantially benefited from the close interactions between the multidisciplinary scientists of the division and with the other Bioinformatics and Biostatistics groups within the DKFZ, e.g. the Theoretical Bioinformatics (B080), Biostatistics (C060) and Molecular Biophysics (B020). The success of the Bioinformatics and Modeling group in biomedical applications is demonstrated by the many collaborative projects carried out within the division and other divisions of the Research Program and beyond the DKFZ.