Dr. Tobias Schafmeier
Position: Scientific Coordinator
Affiliation: DKFZ Molecular Metabolic Control A170
E-mail: t.schafmeier@dkfz.de
Phone: +49-(0)6221-42 3582
Fax: +49-(0)6221-42 3595
Building: DKFZ Main Building
Room: HH1.01.055
EDUCATION
2001-2005
PhD (Dr. rer.nat.)
Heidelberg University, graduated with summa cum laude
1995-2000
Diploma degree in Biology
University of Osnabrück, graduated with very good
PROFESSIONAL EXPERIENCE
07/2011 - today
Scientific Coordinator
Joint Research Division "Molecular Metabolic Control"
German Cancer Research Center (DKFZ) Heidelberg
Center for Molecular Biology (ZMBH) University of Heidelberg
Heidelberg University Hospital
06/2008 - 06/2011
Senior Scientist
Heidelberg University Biochemistry Center (BZH)
06/2005 - 05/2008
Postdoctoral Fellow
Heidelberg University Biochemistry Center (BZH)
10/2001 - 05/2005
PhD Student
Heidelberg University
01/2001 - 09/2001
Research Associate
Ludwig-Maximilians University Munich
MEMBERSHIPS
Member
Gesellschaft für Biochemie und Molekularbiologie (GBM)
Federation of European Biochemical Societies (FEBS)
Int. Union of Biochemistry and Molecular Biology
PUBLICATIONS
·Tobias Schafmeier & Axel Diernfellner (2011). Light input and processing in the circadian clock of Neurospora. FEBS Lett. 585, 1467-1473.
·Axel C.R. Diernfellner & Tobias Schafmeier (2011). Phosphorylations: making the Neurosporacrassa circadian clock tick. FEBS Lett.1461-1466.
·Özgür Tataroglu & Tobias Schafmeier (2010). Of switches and hourglasses: regulation of subcellular distribution in circadian clocks by phosphorylation. EMBO Rep. 11, 927-935.
·Erik Malzahn, Stilianos Ciprianidis, Krisztina Káldi, Tobias Schafmeier & Michael Brunner (2010). Photo-Adaptation in Neurospora Is Mediated by Competitive Interaction of Activating and Inhibitory Light-Oxygen-Voltage Domains. Cell 142, 762-772.
·Stella Tournaviti, Enrica San Pietro, Stefan Terjung, Tobias Schafmeier, Sabine Wegehingel, Julia Ritzerfeld, Juliane Schulz, Deborah F. Smith, Rainer Pepperkok & Walter Nickel (2009). Reversible Phosphorylation as a Molecular Switch to Regulate Plasma Membrane Targeting of Acylated SH4 Domain Proteins. Traffic 10, 1047-1060.
·Gencer Sancar, Cigdem Sancar, Michael Brunner & Tobias Schafmeier (2009). Activity of the circadian transcription factor White Collar Complex is regulated by phosphorylation of SP-motifs. FEBS Lett. 583, 1833-1840.
·Tobias Schafmeier, Axel Diernfellner, Astrid Schäfer, Orfeas Dintsis, Andrea Neiss & Michael Brunner (2008). Circadian activity and abundance rhythms of the Neurospora clock transcription factor WCC associated with rapid nucleo-cytoplasmic shuttling. Genes Dev. 22, 3397-3402.
·Andrea Neiss, Tobias Schafmeier & Michael Brunner (2008). Transcriptional regulation and function of the Neurospora clock gene white collar-2 and its isoforms. EMBO Rep. 9, 788-794.
·Christina Querfurth, Axel Diernfellner, Felix Heise, Linda Lauinger, Andrea Neiss, Özgür Tataroglu, Michael Brunner & Tobias Schafmeier (2007). Posttranslational Regulation of Neurospora Circadian Clock by CK1a-dependent Phosphorylation. Cold Spring Harbor Symp Quant Biol. LXXII, 177-183.
·Michael Brunner & Tobias Schafmeier (2006). Transcriptional and posttranscriptional regulation of the circadian clock of cyanobacteria and Neurospora. Genes Dev. 20, 1061-1074.
·Tobias Schafmeier, Krisztina Káldi, Axel Diernfellner, Christian A. Mohr & Michael Brunner (2006). Phosphorylation dependent maturation of Neurospora circadian clock protein from a nuclear repressor towards a cytoplasmic activator. Genes Dev. 20, 297-306.
·Axel Diernfellner, Tobias Schafmeier, Martha W. Merrow & Michael Brunner (2005). Molecular mechanism of temperature sensing by the circadian clock of Neurospora crassa. Genes Dev. 19, 1968-1973.
·Tobias Schafmeier, Andrea Haase, Krisztina Káldi, Johanna Scholz, Marc Fuchs & Michael Brunner (2005). Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor. Cell 122, 235-246
INVITED TALKS
·The White Collar Complex: light receptor, pacemaker and output regulator of the Neurospora circadian clock. University of Osnabrück, May 2011.
·Light-dependent gene expression and photoadaptation in a filamentous fungus. Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, December 2010.
·Input and signal processing by the circadian clock of Neurospora. BASF Bioscience Symposium 2010, BASF SE Limburgerhof, October 2010
·Circadian activity and abundance rhythms of the Neurospora clock transcription factor WCC. Ludwig-Maximilians-Universität Munich, May 2010.
·Frequency-modulated nucleo-cytoplasmic shuttling cycles are the basis for circadian activity and abundance rhythms of the Neurospora clock transcription factor WCC. 10th European Conference on Fungal Genetics, Leeuwenhorst, March 2010.
·How cells measure time: New insights into circadian clocks. University of Technology Kaiserslautern, November 2009.
·Die innere Uhr: Gene machen unseren Tag. Doctorate granting ceremony, Heidelberg University, December 2005.
·Compartment-specific functions of the clock protein FREQUENCY. SFB-Spring-Meeting, Lindenfels, April 2004.
·Posttranscriptional control of WHITE COLLAR-1 expression in Neurospora crassa is FREQUENCY-mediated and depends on an intact PEST-2 region. 1st Clock-Club-Meeting, Frankfurt, March 2003.