Complete List of Publications
Publications
Fassl, A., Tagscherer, K.E., Richter, J., Berriel Diaz, M., Alcantara Llaguno, S.R., Campos, B., Kopitz, J., Herold-Mende, C., Herzig, S., Schmidt, M. HH, Parada, L.F., Wiestler, O.D. and Roth, W. 2011. Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1. Oncogene: in press
Rose, A.J., Berriel Diaz, M., Reimann, A., Klement, J., Walcher, T., Krones-Herzig, A., Strobel, O., Werner, J., Peters, A., Kleyman, A., Tuckermann, J.P., Vegiopoulos, A. and Herzig, S. 2011. Molecular Control of Systemic Bile Acid Homeostasis by the Liver Glucocorticoid Receptor. Cell Metab. 14: 123–130
Kulozik, Ph., Jones, A., Mattijssen, F., Rose, A. J., Reimann, A., Strzoda, D., Kleinsorg, S., Raupp, Ch., Kleinschmidt, J., Müller-Decker, K., Wahli, W., Sticht, C., Gretz, N., von Loeffelholz, Ch., Stockmann, M., Pfeiffer, A., Stöhr, S., Dallinga-Thie, G. M., Nawroth, P. P., Berriel Diaz M. and Herzig, S. 2011. Hepatic deficiency in transcriptional co-factor TBL1 promotes liver steatosis and hypertriglyceridemia. Cell Metab. 13: 389–400
Jeppesen,J., Albers,P.H., Rose,A.J., Birk,J.B., Schjerling,P., Dzamko,N., Steinberg,G.R., Kiens,B. 2011. Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake is AMPK independent. Journal of Lipid Research 52 (4): 699-711
Vegiopoulos, A., Müller-Decker, K., Strzoda, D., Schmitt, I., Chichelnitskiy, E., Ostertag, A., Berriel Diaz, M., Rozman, J., Hrabe de Angelis, M., Nüsing, R.M., Meyer, C., Wahli, W., Klingenspor, M., and Herzig, S. 2010. COX-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes. Science 328: 1158-1161
Comment in:
Beige can be slimming. Ishibashi, J., Seale, P. 2010. Science May 6
Scientists find a way to trigger fat-burning fat. TIME Magazine May 11, 2010
Kiss,E., Popovic,Z.V., Bedke,J., Adams,J., Bonrouhi,M., Babelova,A., Schmidt,C., Edenhofer,F., Zschiedrich,I., Domhan,S., Abdollahi,A., Schaefer,L., Gretz,N., Porubsky,S., Groene,H.J. 2010. Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage. American Journal of Pathology 176 (5): 2150-2162
Ostertag, A., Jones, A., Rose, A.J., Liebert, M., Kleinsorg, S., Reimann, A., Vegiopoulos, A., Berriel Diaz, M., Strzoda, D., Yamamoto, M., Satoh, T., Akira, S., and Herzig, S. 2010. Control of adipose tissue inflammation through TRB1. Diabetes 59:1991-2000
Haas, B., Mayer, P., Jenissen, K., Ahmad, M., Bloch, W., Berriel Diaz, M., Herzig, S., Fässler, R., and Pfeifer, A. 2009. Protein Kinase G controls insulin-induced brown fat cell differentiation and mitochondrial biogenesis. Sci. Signal. 2: ra78
Chichelnitskiy, E., Vegiopoulos, A., Berriel Diaz, M., Ziegler, A., Kleiman, A., Rauch, A., Tuckermann, J., and Herzig, S. 2009. In vivo PEPCK promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice. Hepatology 50: 1963-1971
Scherneck, S., Nestler, M., Vogel, H., Blüher, M., Block, M.D., Berriel Diaz, M., Herzig, S., Schulz, N., Teichert, M., Tischer, S., Al-Hasani, H., Kluge, R., Schürmann, A., and Joost, H.G. 2009. Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes caused by mouse locus Nidd/SJL. PLOS Genet. 5: e1000541
Narvekar, P., Berriel Diaz, M., Krones-Herzig, A., Hardeland, U., Strzoda, D., Stöhr, S., Frohme, M., and Herzig, S. 2009. Liver-specific Loss of Lipolysis-Stimulated Lipoprotein Receptor Triggers Systemic Hyperlipidemia in Mice. Diabetes 58: 1040-1049
Lemke, U., Krones-Herzig, A., Berriel Diaz, M., Narvekar, P., Ziegler, A., Vegiopoulos, A., Bohl, S., Klingmüller, U., Cato, A., Screaton, R., Müller-Decker, K., Kersten, S., and Herzig, S. 2008. The glucocorticoid receptor controls hepatic dyslipidemia through Hes1. Cell Metab. 8: 212-223
Berriel Diaz, M., Krones-Herzig, A., Metzger, D., Ziegler, A., Vegiopoulos, A., Klingenspor, M., Müller-Decker, K. and Herzig, S. 2008. Nuclear receptor co-factor RIP140 controls lipid metabolism during wasting in mice. Hepatology 48: 782-791
Zschiedrich, I., Hardeland, U., Krones-Herzig, A., Vegiopoulos, A., Berriel Diaz, M., Müggenburg, J., Sombroek, D., Hofmann, T., Zawatzky, R., Yu, X., Gretz, N., Christian, M., White, R., Parker, M.G., and Herzig, S. 2008. Co-activator function of RIP140 for NFkB/RelA-dependent cytokine gene expression. Blood 112: 264-276
Krones-Herzig, A., Mesaros, A., Metzger, D., Ziegler, A., Lemke, U., Brüning, J.C, and Herzig, S. 2006. Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1. J. Biol. Chem. 281: 3025-3029
Dimova, E., Möller, U., Herzig, S., Fink, T., Zachar, V., Ebbesen, P., and Kietzmann, T. 2005. Transcriptional regulation of Plasminogen Activator Inhibitor-1 expression by Insulin-Like Growth Factor-1 via MAP kinases and Hypoxia-Inducible Factor –1 in HepG2 cells. Thromb. Haemost. 93: 1176-1184
Koo, S.-H., Satoh, H., Herzig, S., Lee, C.-H., Hedrick, S., Kulkarni, R., Evans, R.M., Olefsky, J., and Montminy, M. 2004. PGC-1 promotes insulin resistance in liver via the PPARa dependent induction of TRB3. Nat. Med. 10: 530-534
Sawka-Verhelle, D., Escoubet-Lozach, L., Fong, A.L., Hester, K.D., Herzig, S., Lebrun, P., and Glass, C.K. 2004. PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation. J. Biol. Chem. 279: 17772-17784
Herzig, S., Hedrick, S., Morantte, I., Koo, S.-H., Galimi, F., and Montminy, M. 2003. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPARg. Nature 426: 190-193
Comment in:
Why so many of us are getting diabetes. Gorman, C. 2003. Time Magazine 162, Dec 8
Herzig, S.*, Du, K.*, Kulkarni, R., and Montminy, M. 2003. TRB-3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300: 1574-1577
* Authors contributed equally to this work.
Comment in:
Highlights: A sugar fix for fasters. Bussell, K. 2003. Nat. Rev. Mol. Cell. Biol. 4, 512
Putting the brakes on insulin signaling. Saltiel, A.R. 2003. N. Engl. J. Med. 349, 2560-2562
Canettieri, G., Morantte, I., Guzman, E., Asahara, H., Herzig, S., Anderson, S.D., Yates III, J.R., and Montminy. M. 2003. Attenuation of a phosphorylation dependent activator by an HDAC:PP1 complex. Nat. Struc. Biol. 10: 175-181
Herzig, S., Long, F., Jhala, U.S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, D., Schütz, G., Yoon, C., Puigserver, P., Spiegelman, B., and Montminy, M. 2001. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413: 179-183
Comment in:
News and Views: Metabolism: Controlling the glucose factory. Vidal-Puig, A. and O'Rahilly. 2001. Nature 413, 125–126
Herzig, S., Füzesi, L., and Knepel, W. 2000. Heterodimeric Pbx-Prep1 homeodomain protein binding to the glucagon gene restricting transcription in a cell type-dependent manner. J. Biol. Chem. 275: 27989-27999
Beimesche, S., Neubauer, A., Herzig, S., Grzeskowiak, R., Diedrich, T., Cierny, I., Scholz, D., Alejel, T., and Knepel, W. 1999. Tissue-specifictranscriptional activity of a pancreatic islet cell-specific enhancersequence/Pax6-binding site determined in normal adult tissues in vivo using transgenic mice. Mol. Endocrinol. 13: 718-728
Reviews and Book Chapters
Herzig, S. 2012. "Liver: A target of late diabetic complications". Exper. and Clin. Endocrinol. & Diabetes, in press
Sommerfeld, A., Krones-Herzig, A., and Herzig. S. 2010. Transcriptional co-factors and hepatic energy metabolism. Mol. Cell. Endocrinol., in press
Rose, A.J., Vegiopoulos, A., and Herzig, S. 2010. Role of glucocorticoids and the glucocorticoid receptor in metabolism: insights from genetic manipulations. J. Steroid Biochem. Mol. Biol. 122: 10-20
Herzig, S. and Werner, Jens. 2009. Paraneoplastic syndromes. In: Handbook of Pancreatic Cancer. Ed.: John Neoptolemos, Markus Büchler, James Abbruzzese, Raul Urrutia, in press
Jones, A., Kulozik, P., Ostertag, A., and Herzig, S. 2008. Common pathological processes and transcriptional pathways in Alzheimer´s disease and type 2 diabetes. J. Alzheimers Dis. 16: 787-808
Hardeland, U., and Herzig, S. 2008. Molecular mechanisms of muscle atrophy. Bioforum 5: 28-29
Herzig, S. 2007. Molecular control of hepatic gluconeogenesis. Diabetologie 2: 1-3
Vegiopoulos, A. and Herzig, S. 2007. Glucocorticoids, metabolism and metabolic diseases. Mol. Cell. Endocrinol. 275: 43-61
Herzig, S. 2007. Transcription factors in metabolic disease. Dtsch. Med. Wochenschr. 132: 1121-1124
Kleeff, J., Beckhove, P., Esposito, I., Herzig, S., Huber, P.E., Löhr, J.M., and Friess, H. 2007. Pancreatic cancer microenvironment. Int. J. Cancer 121, 699-705
(*All authors contributed equally to this work.)
Berriel Diaz, M., Lemke, U., and Herzig, S. 2006. Discovering orphans’ sweet secret: NR4A receptors and glucose production. Cell Metab. 4: 339-340
Schmoll, D., Herzig, S., and Barthel, A. 2006. Forkhead proteins and the regulation of hepatic gene expression. In: New transcription factors and their role in diabetes and therapy. Advances in Molecular and Cellular Endocrinology, 1st Edition.
Herzig, S. 2005. Insulin resistance: Tracing molecular events. Diabetes Spezial 01/2005: 26-27 (German)
Herzig, S. 2005. Molecular metabolic control. Bioforum 7-8: 2-4 (German)
Barthel, A., Herzig, S., Muller, H.W., Harborth, J., Bornstein, S.R. 2005. RNA interference-based strategies for metabolic syndrome treatment. Horm. Metab. Res. 37: 59-62
