Research Projects:

The research group explores detection techniques at imaging spectrometers with the purpose to characterize tumor tissue by means of biochemical and physiological markers. The group focuses on experimental methods in the field of high–resolution NMR spectroscopy (MRS) and spectroscopic imaging (SI).

NMR (nuclear magnetic resonance), which is applied in many scientific disciplines, enables non–invasive observation of metabolic processes in living tissue (in vivo), while using extremely low–energy electromagnetic radiation.

An MRS application in radiologic diagnostics is the clinical monitoring of tumor patients during radiotherapy and chemotherapy. In cooperation with other medical research groups (within the research program "Imaging and Radiooncology" of the German Cancer Research Center as well as with external groups such as those of the medical clinics of the University of Heidelberg), patients are examined via MRS/SI on whole–body MR tomographs during routine diagnostic and clinical studies. In order to perform these measurements, the research group develops methods for detection of small metabolites, fast spectroscopic imaging for functional studies, and detection of rare nuclei in living tissue.

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