Abstract Submission Deadline 29/05/2017

International Symposium on Personalized Medicine 2017

Deadline 31st May 2017

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BMBF Contribution

Stop signal for dangerous immune responses

Scientists from the German Cancer Research Center (DKFZ) have copied a trick that dying cells use to prevent an undesired immune response. They now plan to develop this biological principle into a therapy method that specifically blocks allergic reactions or autoimmune responses without suppressing the whole immune system. The Federal Ministry of Education and Research (BMBF) contributes funds of €1.3 million to this project.

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Defective intercellular connections cause hydrocephalus

A defective gene leads to changes in the cellular layer between cerebrospinal fluid and brain nervous tissue, thus causing a buildup of fluid in the brain. This link, which scientists from the German Cancer Research Center in Heidelberg have now discovered, is the first known mechanism underlying genetic hydrocephalus.

DKTK

Diagnosis of children’s brain tumors – not every tumor marker is helpful

With the help of molecular tumor diagnostics, cancer medicine is able to filter out individual cancer properties, in order to recommend the most promising and potentially successful treatment options to patients. However, just how reliable such prognoses are also depends on the spatial distribution of the tumor markers inside a tumor. A current study by scientists at the German Cancer Consortium (DKTK) at the University Hospital Düsseldorf shows that for children's brain tumors a single tissue sample suffices in order to make reliable prognoses using gene activity patterns. Comparatively, genetic markers are usually too unevenly distributed in the tumor, thus making several biopsies necessary, the study shows. The DKTK combines the German Cancer Research Center in Heidelberg as the core center together with various university locations across Germany with a specific oncological focus.

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ECEC 2017

Second European Conference on Epigenetics and Cancer

From May 11th to May 13th the German Cancer Research Center is hosting the Second European Conference on Epigenetics and Cancer. About 200 scientists from all over the world will be exchanging views on how small chemical changes in DNA or in their packaging proteins contribute to cancer development, how they could improve cancer diagnosis, or even how they could serve as the target for new cancer therapies.

Latest News

Vitamin A deficiency is detrimental to blood stem cells

Lack of vitamin A in the body has a detrimental effect on the hematopoietic system in the bone marrow. The deficiency causes a loss of important blood stem cells, scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute of Stem Cell Research and Experimental Medicine (HI-STEM) now report in the latest issue of the journal CELL. These are dormant stem cells that only become active in an emergency such as heavy blood loss or infection. These findings will contribute to better comprehending the maturation process of blood cells and also open up new prospects in cancer therapy.

Bi-national Research Unit

Tailor-made viruses for enhanced cancer therapy

Scientists collaborating in a new bi-national research unit that was officially inaugurated on May 2 in Luxemburg aim to develop a second-generation viral therapy for cancer. The two partners in the new alliance are the German Cancer Research Center (DKFZ) in Heidelberg and the Luxembourg Institute of Health (LIH). The researchers plan to develop a method that combines the benefits of oncolytic viruses and of gene therapy. One goal is to treat brain cancer more effectively.

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Research For A Life Without Cancer
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