List of Publications

Slavkovic Lukic, D., A. Hotz-Wagenblatt, J. Lei, A. Räthe, M. Mühle, J. Denner, C. Münk, and M. Löchelt. 2013. Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction. Retrovirology 24;10(1):76. doi: 10.1186/1742-4690-10-76.

Liu, W., J. Lei, Y.Liu, D. Slavkovic Lukic, A.-M. Räthe, Q. Bao, T. Kehl, A. Bleiholder, T. Hechler, and M. Löchelt. 2013 Feline Foamy Virus-Based Vectors: Advantages of an Authentic Animal Model. Viruses 5: 1702-1718.

Kehl, T. A. Bleiholder, F. Roßmann, S. Rupp, J. Lei, J. Lee, W. Boyce, W. Vickers, K. Crooks, S. VandeWoude, and Martin Löchelt. 2013. Complete Genome Sequences of Two Novel Puma concolor Foamy Viruses from California. Genome Announcements 1: 1-2

Mühle, M., K. Hoffmann, M. Löchelt, and J. Denner. 2013. Immunization with foamy virus Bet fusion proteins as novel strategy for HIV-1 epitope delivery. Immunologic Research. 56: 61-72.

Materniak, M., T. Hechler, M. Löchelt, and J. Kuzmak. 2013. Similar patterns of infection with bovine foamy virus in experimentally inoculated calves and sheep. J Virol. 87: 3516-3525.

Hechler, T., M. Materniak, T. Kehl, J. Kuzmak, and M. Löchelt. 2012. Complete genome sequences of two novel European clade bovine foamy viruses from Germany and Poland. J. Virol. 86: 10905-10906.

Chareza, S., D. Slavkovic Lukic, A.-M. Räthe, C. Münk, E. Zabogli, M. Pistello, and M. Löchelt. 2012. Molecular and functional interactions of cat APOBEC3 and feline foamy and immunodeficiency virus proteins: different ways to counteract host-encoded restriction. Virology 424: 138-146.

Mühle, M., M. Löchelt and J. Denner. 2012. Optimisation of expression and purification of the feline and primate foamy virus transmembrane envelope proteins using a 96 deep well screen. Protein Expression and Purification 81: 96-105.

Liu, Y., Y.-B. Kim, and M. Löchelt. 2011. N-terminally myristoylated Feline Foamy Virus Gag allows Env-independent budding of sub-viral particles. Viruses 3: 2223-2237.

Bleiholder, A., M. Mühle, T. Hechler, S. Bevins, S. vandeWoude, J. Denner and M. Löchelt. 2011. Pattern of Seroreactivity Against Feline Foamy Virus Proteins in Domestic Cats from Germany. Vet. Immunol. Immunopathol. 143: 292-300.

Mühle, M., A. Bleiholder, S. Kolb, J. Hübner, M. Löchelt and J. Denner. 2011. Immunological properties of the transmembrane envelope protein of the feline foamy virus and its use for serological screening. Virology 412: 333-340.

Münk, C. T. Hechler, S. Chareza and M. Löchelt. 2010. Restriction of feline retroviruses: lessons from cat APOBEC3 cytidine deaminases and TRIM5alpha proteins. Vet. Immunol. Immunopathol. 134:14-24.

Xu, X., A. zur Hausen, J. Coy, and M. Löchelt. 2009. Role of Transketolase-like protein 1 (TKTL1) in cell growth and viability. Int. J. Cancer 124: 1330-1337.

Perković, M. S. Schmidt, R.A. Russell, B. Stauch, H. Hofmann, F. Kopietz, B.-P. Kloke, J. Zielonka, H. Ströver, J. Hermle, D. Lindemann, V.K. Pathak, G. Schneider, M. Löchelt, K. Cichutek, C. Münk. 2009. Species-Specific Inhibition of APOBEC3C by the Prototype Foamy Virus Bet. J. Biol. Chem. 284: 5819-5826.

Liu, W., P. Backes, and M. Löchelt. 2009. Importance of the major splice donor and redefinition of cis-acting sequences of gutless feline foamy virus vectors. Virology 394: 208-217.

Münk, C., T. Beck, J. Zielonka, A. Hotz-Wagenblatt, S. Chareza, M. Battenberg, J. Thielebein, K. Cichutek, I. G. Bravo, S. O’Brien, M. Löchelt, and N. Yuhki. 2008. Functions, Structure, and Read-Through Alternative Splicing of Feline APOBEC3 Genes. Genome Biol. 9: Mar 3;9(3):R48 [Epub ahead of print].

Bastone, P., F. Romen, W. Liu, R. Wirtz, U. Koch, N. Josephson, S. Langbein, and M. Löchelt. 2007. Construction and Characterization of Efficient, Stable, and Safe Replication-Deficient Foamy Virus Vectors. Gene Therapy 14: 613-620.

Romen, F., P. Backes, M. Materniak, R. Sting, T. W. Vahlenkamp, R. Riebe, M. Pawlita, J. Kuzmak, and M. Löchelt. 2007. Serological Detection Systems for Identification of Cows Shedding Bovine Foamy Virus Via Milk. Virology 364: 123-131.

Münk, C., J. Zielonka, H. Constabel, B.-P. Kloke, B. Rengstl, M. Battenberg, F. Bonci, M. Pistello, M. Löchelt, and K. Cichutek 2007. Multiple Restrictions of Human Immunodeficiency Virus Type 1 in Feline Cells. J. Virol. 81: 7048-7060.

Romen, F., M. Pawlita, P. Sehr, S. Bachmann, J. Schröder, H. Lutz, and M. Löchelt. 2006. Antibodies against Gag are diagnostic markers for feline foamy virus infections while Env and Bet reactivity is undetectable in a substantial fraction of infected cats. Virology 345: 502-508.

Bastone, P., I. G. Bravo, and M. Löchelt. 2006. Feline Foamy Virus-Mediated Marker Gene Transfer: Identification of Essential Genetic Elements and Influence of Truncated and Chimeric Proteins. Virology 348: 190-199.

Lehmann-Che, J., M.-L. Giron, O. Delelis, M. Löchelt, P. Bittoun, J. Tobaly-Tapiero, H. de The, and A. Saib. 2005. Protease-dependent uncoating of a complex retrovirus. J. Virol. 79: 9244-9253.

Löchelt, M., F. Romen, P. Bastone, H. Muckenfuss, N. Kirchner, Y.-B. Kim, U. Truyen, U. Rösler, M. Battenberg, A. Saib, E. Flory, K. Cichutek, and C. Münk. 2005. The anti-retroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein. Proc. Natl. Acad. Sci. U.S.A. 102: 7982-7987.

Bastone, P. and M. Löchelt. 2004. Kinetics and characteristics of replication-competent revertants derived from self-inactivating foamy virus vectors. Gene Ther. 11: 465-473.

Geiselhart, V., P. Bastone, T. Kempf, M. Schnölzer, and M. Löchelt. 2004. Furin-Mediated Cleavage of the Feline Foamy Virus Env Leader Protein. J. Virol. 78: 13573-13581.

Geiselhart, V., A. Schwantes, P. Bastone, M. Frech, and M. Löchelt. 2003. Features of the Env leader protein and the N-terminal Gag domain of feline foamy virus important for virus morphogenesis. Virology 310: 235-244.

Schwantes, A., U. Truyen, J. Weikel, C. Weiss, and M. Löchelt. 2003. Application of chimeric feline foamy virus-based retroviral vectors for the induction of antiviral immunity in cats. J. Virol. 77: 7830-7842.

Weikel, J., M. Löchelt, and U. Truyen. 2003. Demonstration of feline foamy virus in experimentally infected cats by immunohistochemistry. J. Vet. Med. A 50: 415-417.

Bastone, P., U. Truyen, and M. Löchelt. 2003. Potential of Zoonotic Transmission of Non-Primate Foamy Viruses to Humans. J. Vet. Med. B 50: 417-423.

Löchelt, M. 2003. Foamy virus transactivation and gene expression. Curr. Top. Microbiol. Immunol. 277: 27-61.

Wilk, T., V. Geiselhart, M. Frech, S.D. Fuller, R.M. Flügel, and M. Löchelt. 2001. Specific interaction of a novel foamy virus Env leader protein with the N-terminal Gag domain. J. Virol. 75: 7995-8007.

Alke, A., A. Schwantes, K. Kido, M. Flötenmeyer, R.M. Flügel, and M. Löchelt. 2001. The bet Gene of feline foamy virus is required for virus replication. Virology 287: 310-320.

Zemba, M., A. Alke, J. Bodem, I.G. Winkler, R.L.P. Flower, K.-I. Pfrepper, H. Delius, R. M. Flügel, and M. Löchelt. 2000. Construction of infectious feline foamy virus genomes: cat antisera do not cross-neutralize feline foamy virus chimera with serotype-specific Env sequences. Virology 266: 150-156.

Wilk, T., F. deHaas, A. Wagner, T. Rutten, S. Fuller, R.M. Flügel, and M. Löchelt. 2000. The intact retroviral Env glycoprotein of human foamy virus is a trimer. J. Virol. 74: 2885-2887.

Winkler, I., J. Bodem, L. Haas, M. Zemba, H. Delius, R.P. Flower, R.M. Flügel, and M. Löchelt. 1997. Characterization of the genome of feline foamy virus and its proteins shows distinct features different from primate spumaviruses. J. Virol. 71: 6727-6741.

Löchelt, M., and R.M. Flügel. 1996. The human foamy virus pol gene is expressed as a Pro-Pol polyprotein and not as a Gag-Pol fusion protein. J. Virol. 70: 1033-1040.

Löchelt, M., S.F. Yu, M.L. Linial, and R.M. Flügel. 1995. The human foamy virus internal promoter is required for efficient gene expression and infectivity. Virology 206: 601-610.

Konvalinka, J., M. Löchelt, H. Zentgraf, R.M. Flügel, and H.-G. Kräusslich. 1995. Active spumavirus proteinase is essential for virus infectivity but not for formation of the Pol polyprotein. J. Virol. 69: 7264-7268.

Löchelt, M., R.M. Flügel, and M. Aboud. 1994. The human foamy virus internal promoter directs the expression of the functional Bel 1 transactivator and Bet protein early after infection. J. Virol. 68: 38-645.

Löchelt, M., W. Muranyi, and R.M. Flügel. 1993. Human foamy virus genome posesses an internal, Bel-1-dependent and functional promoter. Proc. Natl. Acad. Sci. U.S.A. 90: 7317-7321.

Löchelt, M., M. Aboud, and R.M. Flügel. 1993. Increase in the basal transcriptional activity of the human foamy virus internal promoter by the homologous long terminal repeat promoter in cis. Nucleic Acids Research 21: 4226-4230.

Keller, A., K.M. Partin, M. Löchelt, H. Bannert, R.M. Flügel, and B.R. Cullen. 1991. Characterization of the transcriptional trans-activator of human foamy retrovirus. J. Virol. 65: 2589-2594.

Löchelt, M., H. Zentgraf, and R.M. Flügel. 1991. Construction of an infectious DNA clone of the full-length human spuma-retrovirus genome and mutagenesis of the bel1 gene. Virology 184: 43-54.

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