ORIGINAL PAPERS

1. Rommelaere, J. and Errera, M. (1972)
The effect of caffeine on the survival of UV-irradiated diploid and tetraploid Chinese hamster cells.
International Journal of Radiation Biology, 22, 285-291.
2. Errera, M. and Rommelaere, J. (1973)
Do mammalian cells have a recombination repair system?
In : "Proceedings of the Symposium on Control Mechanisms in Cellular Processes". Bhabha Atomic Research Center, Bombay, pp. 671-679.
3. Rommelaere, J., Susskind, M. and Errera, M. (1973)
Chromosome and chromatid exchanges in Chinese hamster cells.
Chromosoma, 41, 243-257.
4. Rommelaere, J., Cornelis, J.J., Miller-Faurès, A. and Errera, M. (1974)
The influence of 5-bromodeoxyuridine on DNA repair in Chinese hamster cells exposed to ultraviolet radiation.
Biochimica and Biophysica Acta, 340, 388-399.
5. Rommelaere, J., Miller-Faurès, A. and Errera, M. (1974)
Isolation of replicating DNA segments from Chinese hamster cells by density equilibrium centrifugation.
Journal of Molecular Biology, 90, 491-508.
6. Rommelaere, J. and Miller-Faurès, A. (1975)
Detection by density equilibrium centrifugation of recombinant -like DNA molecules in somatic mammalian cells.
Journal of Molecular Biology, 98, 195-218.
7. Rommelaere, J. and Hiernaux, J. (1975)
Model for the positional differentiation of the cap in Acetabularia.
Biosystems, 7, 250-258.
8. Rommelaere, J., Miller-Faurès, A. and Errera, M. (1975) Detection of possible heteroduplexes in Chinese hamster cells DNA by molecular autoradiography.
Archives de Biologie, 86, 323-332.
9. Cornelis, J.J., Rommelaere, J., Urbain, J. and Errera, M. (1977)
A sensitive immunological method for measuring pyrimidine dimers in situ.
Photochemistry and Photobiology, 26, 241-246.
10. Tondeur, F. and Rommelaere, J. (1977).
Interaction of caffeine with DNA of Chinese hamster cells.
Biochimica and Biophysica Acta, 475, 562-570.
11. Rommelaere, J., Faller, D.V. and Hopkins, N. (1977)
RNAse T1-resistant oligonucleotides of Akv-1 and Akv-2 type C viruses of AKR mice.
Journal of Virology, 24, 690-694.
12. Rommelaere, J., Faller, D.V. and Hopkins, N. (1978) Characterization and mapping of RNAse T-1 resistant oligonucleotides derived from the genome Akv and MCF murine leukemia viruses.
Proceedings of the National Academy of Sciences USA., 75, 495-499.
13. Rommelaere, J., Faller, D.V. and Hopkins, N. (1978)
Analysis of the genomes of leukemia viruses of the AKR mouse.
In: "Cold Spring Harbor Conference on Cell Proliferation". Cold Spring Harbor Press, vol. 5, pp. 561-575.
14. Hopkins, N., Faller, D.V., Rommelaere, J. and Schindler, J. (1978)
Analysis of murine leukemia virus recombinants.
In : "Proceedings of the ICN-UCLA Symposium on Persistent Viruses".
Academic Press, New York,.pp. 345-361.
15. Faller, D., Rommelaere, J. and Hopkins, N. (1978)
Large T1 oligonucleotides of Moloney leukemia virus missing in an env gene recombinant, HIX are present on an intracellular 21S Moloney viral RNA species.
Proceedings of the National Academy of Sciences USA, 75, 2964-2968.
16. Rommelaere, J., Donis-Keller, H. and Hopkins, N. (1979)
RNA sequencing provides evidence for allelism of determinants of the N-, B- or NB-tropism of murine leukemia viruses.
Cell, 16, 43-45.
17. Donis-Keller, H., Rommelaere, J., Ellis, R.W. and Hopkins, N. (1980)
Nucleotide sequences associated with the electrophoretic mobility of gp70 and the Glx phenotypes of certain murine leukemia viruses.
Proceedings of the National Academy of Sciences USA, 77, 1642-1645.
18. Rommelaere, J., Vos, J-M., Cornelis, J.J. and Ward, D.C. (1981)
UV-enhanced reactivation of Minute-Virus-of-Mice: stimulation of a late step in the viral life cycle.
Photochemistry and Photobiology, 33, 845-854.
19. Cornelis, J.J., Su, Z.Z., Ward, D.C. and Rommelaere, J. (1981)
Indirect induction of mutagenesis of intact parvovirus H-1 in mammalian cells treated with UV light or with UV-irradiated H-1 or SV40 viruses.
Proceedings of the National Academy of Sciences USA, 78, 4480-4484.
20. Vos, J-M., Cornelis, J.J., Limbosch, S., Zampetti-Bosseler, F. and Rommelaere, J. (1981)
UV-irradiation of related mouse hybrid cells: similar increase in capacity to replicate intact Minute-Virus-of-Mice but differential enhancement of survival of UV-irradiated virus.
Mutation Research, 83, 171-178.
21. Su, Z.Z., Cornelis, J.J. and Rommelaere, J. (1981)
Mutagenesis of intact parvovirus H-1 is expressed coordinately with enhanced reactivation of ultraviolet irradiated virus in human and rat cells treated with 2-nitronaphthofurans.
Carcinogenesis, 2, 1039-1043.
22. Luo, Z.Y., Cornelis, J.J., Vos, J.M. and Rommelaere, J. (1982)
UV-enhanced reactivation of capsid protein synthesis and infectious centre formation in mouse cells infected with UV- irradiated Minute-Virus-of-Mice.
International Journal of Radiation Biology, 40, 119-126.
23. Rommelaere, J. and Ward, D.C. (1982)
Effect of UV-irradiation on DNA replication of the parvovirus Minute-Virus-of-Mice in mouse fibroblasts.
Nucleic Acids Research, 10, 2577-2596.
24. Vos, J-M. and Rommelaere, J. (1982)
Réactivation de la réplication du DNA du parvovirus MVM dans les cellules de souris préexposées au rayonnement UV.
Comptes-rendus de la Société de Biologie (Paris), 176, 395-401.
25. Cornelis, J.J., Su, Z.Z. and Rommelaere, J. (1982)
Direct and indirect effects of ultraviolet light on the mutagenesis of parvovirus H-1 in human cells.
The EMBO Journal, 1, 693-699.
26. Vos, J-M. and Rommelaere, J. (1982)
Are pyrimidine dimers tolerated during DNA replication of UV-irradiated parvovirus Minute-Virus-of-Mice in mouse fibroblasts?
Biochimie, 64, 839-844.
27. Cornelis, J.J., Su, Z.Z., Dinsart, C. and Rommelaere, J. (1982)
Ultraviolet-irradiated Simian Virus 40 activate a mutator function in rat cells under conditions preventing viral DNA replication.
Biochimie, 64, 677-680.
28. Mousset, S. and Rommelaere, J. (1982)
Minute-Virus-of-Mice inhibits cell transformation by Simian Virus 40.
Nature, 300, 537-539.
29. Cornelis, J.J., Dinsart, C., Su, Z.Z. and Rommelaere, J. (1983)
Parvoviral probe for assessing the mutagenic risk of low doses of radiation and chemicals administered to human cells.
In: "The Use of Human Cells for the Assessment of Risk from Physical and Chemical Agents", ed. A. Castellani. Plenum Press, New York, pp. 119-140.
30. Rommelaere, J., Vos, J-M. and Ward, D.C. (1983)
Parvoviral probe of DNA replication in mammalian cells exposed to genotoxic agents.
In: "The Use of Human Cells for the Assessment of Risk from Physical and Chemical Agents", ed. A. Castellani. Plenum Press, New York, pp. 237-261.
31. Hardt, N., Dinsart, C., Spadari, S., Pedrali-Noy, G. and Rommelaere, J. (1983)
Interrelation between viral and cellular DNA synthesis in mouse cells infected with the parvovirus Minute-Virus-of-Mice.
Journal of General Virology, 64, 1991-1998.
32. Vos, J-M., Avalosse, B., Su, Z.Z. and Rommelaere,J. (1984)
Inhibition and recovery of the replication of depurinated parvovirus DNA in mouse fibroblasts.
In: "Proteins Involved in DNA Replication", eds. U. Hubscher and S. Spadari. Plenum Press, New York, pp. 143-150.
33. Dinsart, C., Cornelis, J.J., Klein, B., van der Eb, A. and Rommelaere, J. (1984)
Transfection with extracellularly UV-damaged DNA induces human and rat cells to express a mutator phenotype towards parvovirus H-1.
Molecular and Cellular Biology, 4, 324-328.
34. Su, Z.Z., Avalosse, B., Vos, J-M., Cornelis, J.J. and Rommelaere, J. (1985)
Mutagenesis at putative apurinic sites in alkylated single- stranded DNA of Parvovirus H-1 propagated in human cells.
Mutation Research, 149, 1-8.
35. Dinsart, C., Cornelis, J.J., Decaesstecker, M., van der Lubbe, J., van der Eb, A.J. and Rommelaere, J. (1985)
Differential effect of ultraviolet light on the induction of SV40 and a cellular mutator phenotype in transformed mammalian cells.
Mutation Research, 151, 9-14.
36. van der Lubbe, J.L.M., van Drunen, C.M., Hertoghs, J.J.L., Cornelis, J.J, Rommelaere, J. and van der Eb, A.J. (1985)
Enhanced induction of SV40 replication from transformed mammalian cells by fusion with UV-irradiated untransformed cells.
Mutation Research, 151, 1-8.
37. Hilgers, G., Deleys-Hertoghs, J., Cornelis, J.J., Klein, B. and Rommelaere, J. (1985)
Réactivation du parvovirus H-1 irradié aux rayons gamma dans les cellules de patients atteints d'Ataxia telangiectasia et de la chorée de Huntington.
Comptes-rendus de la Société de Biologie, 179, 283-287.
38. de Foresta, F., Deleys-Hertoghs, J., Cornelis, J.J., Klein, B. et Rommelaere, J. (1985)
La transformation par le virus SV40 sensibilise les fibroblastes de peau humaine à l'action lytique du Parvovirus H-1.
Comptes-rendus de la Société de Biologie, 179, 276-282.
39. Cornelis, J.J. and Rommelaere, J. (1985)
Timing of ultraviolet light-induced mutagenesis in SV40 relative to viral DNA replication in monkey cells.
Molecular and General Genetics, 201, 421-425.
40. Kisary, J., Avalosse, B., Miller, A. and Rommelaere, J. (1985)
The genome structure of a new chicken virus identifies it as a parvovirus.
Journal of General Virology, 66, 2259-2263.
41. Y.Q. Chen, de Foresta, F., Hertoghs, J., Avalosse, B., Cornelis, J.J. and Rommelaere, J. (1986)
Selective killing of SV40-transformed human fibroblasts by parvovirus H-1.
Cancer Research, 46, 3574-3579.
42. Mousset, S., Cornelis, J.J., Spruyt, N. and Rommelaere, J. (1986)
Transformation of established murine fibroblasts with an activated cellular Harvey ras oncogene or the polyoma virus middle T gene increases cell permissiveness to Parvovirus MVM.
Biochimie, 68, 951-956.
43. Kisary, J., Miller-Faurès, A. and Rommelaere, J. (1987)
Presence of fowl parvovirus in fibroblast cell cultures prepared from uninoculated white Leghorn chicken embryos.
Avian Pathology, 16, 115-121.
44. Avalosse, B.L., Chen, Y.Q.., Cornelis, J.J., Duponchel, N., Becquart, P., Namba, M. and Rommelaere, J. (1987)
Amplification of parvoviral DNA as a function of host cell transformation.
In : "Accomplishments in Oncology", eds. H. zur Hausen and J.R. Schlehofer. J.B. Lippincott Publ., Philadelphia, vol. 2, pp. 140-152.
45 Hilgers, G., Chen, Y.Q., Cornelis, J.J. and Rommelaere, J. (1987)
Deficient expression of enhanced reactivation of parvovirus H-1 in Ataxia telangiectasia cells irradiated with X-rays or UV-light.
Carcinogenesis, 8, 315-319.
46. Vos, J.M. and Rommelaere, J. (1987)
Replication of DNA containing apurinic sites in human and mouse cells probed with parvoviruses MVM and H-1.
Molecular and Cellular Biology, 7, 2620-2624.
47. Mousset, S. and Rommelaere, J. (1988)
Susceptibility to parvovirus Minute - Virus - of - Mice as a function of the degree of host cell transformation : little effect of Simian Virus 40 infection and phorbolester treatment.
Virus Research, 9, 107-117.
48. Hilgers, G., Abrahams, P.J., Schouten, R., Cornelis, J.J., Lehmann, A.R., van der Eb, A.J. and Rommelaere, J. (1988)
Les cellules de patients atteints d'ataxia telangiectasia manifestent une capacité normale de réactivation radioinduite du virus HSV - 1 endommagé.
Comptes rendus de la Société de Biologie, 181, 432-438.
49. Cornelis, J.J., Becquart, P., Duponchel, N., Salomé, N. Avalosse, B.L., Namba, M. and Rommelaere, J. (1988)
Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen or simian virus 40 correlates with an increase in their susceptibility to the autonomous parvoviruses H-1 and Minute Virus of Mice.
Journal of Virology, 62, 1679-1686.
50. Su, Z.Z., Luo, Z.Y., Guo, L.P., Dupont, F., Avalosse, B. and Rommelaere, J. (1988)
Positive selection of human cells lacking several transformation parameters from an SV40 - transformed culture by means of parvovirus H-1.
Carcinogenesis, 9, 1395-1400.
51. Cornelis, J.J., Spruyt, N., Spegelaere, P., Guetta, E., Darawshi, T., Cotmore, S.F., Tal, J. and Rommelaere, J. (1988)
Sensitization of transformed rat fibroblasts to killing by parvovirus MVM correlates with an increase in viral gene expression.
Journal of Virology, 62, 3438-3444.
52. Hilgers, G., Cornelis, J., Abrahams, P., Schouten, R., van der Eb, A. and Rommelaere, J. (1988)
Differential reactivation and mutagenesis of single - and double - stranded DNA viruses in irradiated cells from ataxia telangiectasia patients
In : "Light in Biology and Medicine", eds. R.H. Douglas, J. Moan and F. Dall'Acqua. Plenum Press, New York, vol 1, pp. 233-240.
53. Chen, Y.Q., Tuynder, M.C., Cornelis, J.J., Boukamp, P., Fusenig, N.E. and Rommelaere, J. (1989)
Sensitization of human keratinocytes to killing by parvovirus H-1 takes place during their malignant transformation but does not require them to be tumorigenic.
Carcinogenesis, 10, 163-167.
54. Hilgers, G., Abrahams, P.J., Chen, Y.Q., Schouten, R., Cornelis, J.J., van der Eb, A.J. and Rommelaere, J. (1989)
Impaired recovery and mutagenic SOS-like responses in ataxia telangiectasia cells.
Mutagenesis, 4, 271-276.
55. van Hille, B., Duponchel, N., Salomé, N., Spruyt, N., Cotmore, S.F., Tattersall, P., Cornelis, J.J. and Rommelaere, J. (1989)
Limitations to the expression of parvoviral nonstructural proteins may determine the extent of sensitization of EJ ras-transformed rat cells to Minute Virus of Mice.
Virology, 171, 89-97.
56. Dupressoir, T., Vanacker, J.M., Cornelis, J.J., Duponchel, N. and Rommelaere, J. (1989)
Inhibition by parvovirus H-1 of the formation of tumors in nude mice and colonies in vitro by transformed human mammary epithelial cells.
Cancer Research, 49, 3203-3208.
57. Salome, N., van Hille, B., Geuskens, M. and Rommelaere, J. (1989)
Partial reversion of conditional transformation correlates with a decrease in the sensitivity of rat cells to killing by parvovirus MVMp but not in their capacity for virus production: effect of a temperature - sensitive v-src oncogene.
Journal of Virology, 63, 4797-4807.
58. Avalosse, B.L., Barrijal, S., Chen, Y.Q., Cassiman, J-J., and Rommelaere, J. (1989)
Identification of a transformation-sensitive nuclear protein from normal human fibroblasts, that specifically interacts with Minute Virus of Mice DNA and correlates with cell resistance to the parvovirus.
Molecular Carcinogenesis, 2, 245-251.
59. Salome, N., van Hille, B., Duponchel, N., Meneguzzi, G., Cuzin, F., Rommelaere, J. and Cornelis, J.J. (1990)
Sensitization of transformed rat cells to parvovirus MVMp is restricted to specific oncogenes.
Oncogene, 5, 123-130.
60. Guetta, E., Mincberg, M., Mousset, S., Bertinchamps, C., Rommelaere, J. and Tal, J. (1990)
The selective killing of transformed rat cells by Minute Virus of Mice does not require infectious virus production.
Journal of Virology, 64, 458-462.
61. Brandenburger, A., Legendre, D., Avalosse, B. and Rommelaere, J. (1990)
NS-1 and NS-2 proteins may act synergistically in the cytopathogenicity of parvovirus MVMp.
Virology, 174, 576-584.
62. Cornelis, J.J., Chen, Y.Q., Spruyt, N., Duponchel, N., Cotmore, S.F., Tattersall, P. and Rommelaere, J. (1990)
Susceptibility of human cells to killing by the parvoviruses H-1 and minute virus of mice correlates with viral transcription.
Journal of Virology, 64, 2537-2544.
63. Caillet-Fauquet, P., Perros, M., Brandenburger, A., Spegelaere, P. and Rommelaere, J. (1990)
Programmed killing of human cells by means of an inducible clone of parvoviral genes encoding non-structural proteins.
The EMBO Journal, 9, 2989-2995.
64. Plaza, S., Boullard, A., Pelé, D., Cornelis, J.J., Rommelaere, J., Giacomoni, P.U. and Prunieras, M. (1991)
Unscheduled DNA synthesis: a quantitative indicator of residual antigenic pyrimidine dimers in human fibroblasts after UVB irradiation.
Photochemistry and Photobiology, 53, 217-227.
65. Tuynder, M., Godfrine, S., Cornelis, J.J. and Rommelaere, J. (1991)
Dose-dependent induction of resistance to terminal differentiation in X-irradiated cultures of normal human keratinocytes.
Proceedings of the National Academy of Sciences USA, 88, 2638-2642.
66. Hilgers, G., Clauss, I.M., Huez, G.A. and Rommelaere, J. (1991)
Post-transcriptional effect of ultraviolet light on gene expression in human cells : stabilization of cytokine-and poly(I)-poly(C)-induced messenger RNAs.
European Journal of Biochemistry, 201, 483-488.
67. Spegelaere, P., van Hille, B., Spruyt, N., Faisst, S., Cornelis, J.J. and Rommelaere, J. (1991)
Initiation of transcription from the minute virus of mice P4 promoter is stimulated in rat cells expressing a c-Ha-ras oncogene.
Journal of Virology, 65, 4919-4928.
68. Russell, S., Brandenburger, A., Flemming, C.L., Collins, M.K.L. and Rommelaere, J. (1992)
Transformation-dependent expression of interleukin genes delivered by a recombinant parvovirus.
Journal of Virology, 66, 2821-2828.
69. Perros, M., Vanacker, J.M., Koering, C., Dupressoir, T., Faisst, S. and Rommelaere, J. (1992)
Etude des interactions du parvovirus MVMp avec les cellules transformées.
In : "Interactions Virus-Cellules". Coll. de la Société Française de Microbiologie/Virologie, XI, 157-172.
70. Legrand, C., Mousset, S., Salomé, N. and Rommelaere, J. (1992)
Cooperation of oncogenes in cell transformation and sensitization to killing by parvovirus minute virus of mice.
Journal of General Virology, 73, 2003-2009.
71. Legendre, D. and Rommelaere, J. (1992)
Terminal regions of the NS-1 protein of parvovirus MVMp are involved in cytotoxicity and promoter trans-inhibition.
Journal of Virology, 66, 5705-5713.
72. Barrijal, S., Perros, M., Gu Z.N., Avalosse, B.L., Belenguer, P., Amalric, F. and Rommelaere, J. (1992)
Nucleolin forms a specific complex with a fragment of the viral (minus) strand of minute virus of mice DNA.
Nucleic Acids Research, 20, 5053-5060.
73. Bossens, M., Van Pachterbeke, C., Tuynder, M., Parent, D., Heenen, M. and Rommelaere, J. (1992)
In vitro infection of normal human keratinocytes by HPV-1 followed by amplification of the viral genome in reconstructed epidermis.
Journal of General Virology, 73, 3269-3273.
74. Legrand, C., Rommelaere, J. and Caillet-Fauquet, P. (1993)
MVM(p) NS-2 protein expression is required with NS-1 for maximal cytotoxicity in human transformed cells.
Virology, 195, 149-155.
75. Telerman, A., Tuynder, M., Dupressoir, T., Robaye, B., Sigaux, F., Shaulian, E., Oren, M., Rommelaere, J. and Amson, A. (1993)
A model for tumor suppression using H-1 parvovirus.
Proceedings of the National Academy of Sciences USA, 90, 8702-8706.
76. Van Pachterbeke, C., Tuynder, M., Cosyn, J.P., Lespagnard, L., Larsimont, D. and Rommelaere, J. (1993)
Parvovirus H-1 inhibits growth of short-term tumour-derived but not normal mammary tissue cultures.
International Journal of Cancer, 55, 672-677.
77. Faisst, S.R., Faisst, S., Grangette, C., Schlehofer, J.R. and Rommelaere, J. (1993)
NFB upstream regulatory sequences of the HIV-1 LTR are involved in the inhibition of HIV-1 promoter activity by the NS proteins of autonomous parvoviruses H-1 and MVMp.
Virology, 197, 770-773.
78. Tenenbaum, L., Dupont, F., Spegelaere, P., Zentilin, L., Norio, P., Giacca, M., Riva, S., Falaschi, A. and Rommelaere, J. (1993)
Inhibition of heterologous DNA replication by the MVMp non-structural NS-1 protein: identification of a target sequence.
Virology, 197, 630-641.
79. Vanacker, J.M., Laudet, V., Adelmant, G., Stéhelin, D. and Rommelaere, J. (1993)
Interconnection between thyroid hormone signalling pathways and parvovirus cytotoxic functions.
Journal of Virology, 67, 7668-7672.
80. Becquart, P., Vanacker, J.M., Duponchel, N., Bègue, A. and Rommelaere, J. (1993)
Expression of the nonstructural proteins of parvovirus MVMp from recombinant retroviruses: predominant role of the parvoviral NS-1 product in host cell disturbance.
Research in Virology, 144, 465-470.
81. Dupont, F., Tenenbaum, L., Guo, L.P., Spegelaere, P., Zeicher, M. and Rommelaere, J. (1994)
Use of an autonomous parvovirus vector for selective transfer of a foreign gene into transformed human cells of different tissue origins and its expression therein.
Journal of Virology, 68, 1397-1406.
82. Spegelaere, P., Cornelis, J.J., Tuynder, M. and Rommelaere, J. (1994)
Lack of a detectable effect of capsid proteins on the cell-dependent activity of parvovirus MVMp promoters.
Research in Virology,145, 5-12.
83. Koering, C.E., Dupressoir, T., Plaza, S., Stehelin, D. and Rommelaere, J. (1994)
Induced expression of the conditionally cytotoxic Herpes simplex virus thymidine kinase gene by means of a parvoviral regulatory circuit.
Human Gene Therapy, 5, 457-463.
84. Faisst, S., Perros, M., Deleu, L., Spruyt, N. and Rommelaere, J. (1994)
Mapping of upstream regulatory elements in the P4 promoter of parvovirus minute virus of mice.
Virology, 202, 466-470.
85. Perros, M., Spegelaere, P., Dupont, F., Vanacker, J.-M. and Rommelaere, J. (1994)
Cruciform structure of a parvovirus MVMp DNA motif involved in the attenuation of gene expression.
Journal of General Virology, 75, 2645-2653.
86. Mousset, S., Ouadrhiri, Y., Caillet-Fauquet, P. and Rommelaere, J. (1994)
The cytotoxicity of parvovirus MVMp non-structural proteins in FR 3T3 rat cells depends on oncogene expression.
Journal of Virology, 68, 6446-6453.
87. Legendre, D. and Rommelaere, J. (1994)
Targeting of promoters for trans-activation by a carboxy-terminal domain of the NS-1 protein of parvovirus MVMp.
Journal of Virology, 68, 7974-7985.
88. Gu, Z.-N., Plaza, S., Perros, M., Cziepluch, C., Rommelaere, J. and Cornelis, J.J. (1995)
NF-Y controls transcription of the minute virus of mice P4 promoter through interaction with an unusual binding site.
Journal of Virology, 69, 239-246.
89. Faisst, S., Faisst, S.R., Dupressoir, T., Plaza, S., Pujol, A., Jauniaux, J.C., Rhode, S. and Rommelaere, J. (1995)
Isolation of a fully infectious variant of parvovirus H-1 supplanting the standard strain in human cells.
Journal of Virology, 69, 4538-4543.
90. Op De Beeck, A., Anouja, F., Mousset, S., Rommelaere, J. and Caillet-Fauquet, P. (1995)The nonstructural (NS) proteins of the autonomous parvovirus minute virus of mice interfere with the cell cycle, inducing accumulation in G2.
Cell Growth & Differentiation, 6, 781-787.
91. Perros, M., Deleu, L., Vanacker, J.-M., Kherrouche, Z., Spruyt, N., Faisst, S. and Rommelaere, J. (1995)
Upstream CREs participate in the basal activity of minute virus of mice promoter P4 and in its stimulation in ras-transformed cells.
Journal of Virology, 69, 5506-5515.
92. Fuks, F., Deleu, L., Dinsart, C., Rommelaere, J. and Faisst, S. (1996)
Ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors.
Journal of Virology, 70, 1331-1339.
93. Koering, C. E., Geuskens, M. and Rommelaere, J. (1996)
Continuous production of minute virus of mice (MVMp) by an untransformed variant of Fisher rat fibroblast (FR3T3).
Journal of General Virology, 77, 447-452.
94. Vanacker, J.M., Corbau, R., Adelmant, G., Perros, M., Laudet, V. and Rommelaere, J. (1996)
Transactivation of a cellular promoter by the NS1 protein of parvovirus Minute Virus of Mice through a putative hormone-responsive element.
Journal of Virology, 70, 2369-2377.
95. Koering, C. E., Vennin-Fikry, M., Dupressoir, T., Schlehofer, J. R., Rommelaere, J. and Stéhelin, D. (1996)
Sensitivity to the parvovirus MVMp as a probe for azatyrosine-mediated phenotypic reversion of spontaneously transformed cells.
Journal of General Virology, 77, 913-917.
96. Brockhaus, K., Plaza, S., Pintel, D.J., Rommelaere, J. and Salomé, N. (1996)
Nonstructural proteins NS2 of minute virus of mice associate in vivo with 14-3-3 protein family members.
Journal of Virology, 70, 7527-7534.
97. López-Guerrero, J.A., Rayet, B., Tuynder, M., Rommelaere, J. and Dinsart, C. (1997) Constitutive activation of U937 promonocytic cell clones selected for their resistance to parvovirus H-1 infection.
Blood, 89,1642-1653.
98. Baldauf, A.Q., Willwand, K., Mumtsidu, E. Nüesch, J.P.F. and Rommelaere, J. (1997)
Specific initiation of replication at the 5'telomere of the circular species of minute virus of mice DNA.
Journal of Virology, 71, 971-980.
99. Van Pachterbeke, C., Tuynder, M., Brandenburger, A., Leclercq, G., Borras, M. and Rommelaere, J. (1997)
Varying sensitivity of human mammary carcinoma cells to the toxic effect of parvovirus H-1. European Journal of Cancer, 33, 1648-1653.
100. Pujol, A., Deleu, L., Nüesch, J.P.F., Cziepluch, C., Jauniaux, J-C. and Rommelaere, J.(1997)
Inhibition of parvovirus minute virus of mice replication by a peptide involved in the oligomerization of the non-structural protein NS1.
Journal of Virology , 71, 7393-7403.
101. Willwand, K., Baldauf, A.Q., Deleu, L., Mumtsidu, E., Costello, E., Beard, P. and
Rommelaere, J. (1997)
The minute virus of mice (MVM) non-structural protein NS1 induces nicking of MVM DNA at a unique site of the right-end telomere in both hairpin and duplex conformations in vitro.
Journal of General Virology, 78, 2647-2655.
102. Faisst, S., Guittard, D., Benner, A., Cesbron, J.Y., Schlehofer, J.R., Rommelaere, J.and Dupressoir, T. (1998)
Dose-dependent regression of HeLa cell-derived tumours in SCID mice after parvovirus H-1 infection.
International Journal of Cancer, 75, 584-589.
103. Willwand, K., Mumtsidu, E., Kuntz-Simon, G. and Rommelaere, J. (1998)
Initiation of DNA replication at palindromic telomeres is mediated by a duplex-to-hairpin transition induced by the minute virus of mice non-structural protein NS1.
Journal of Biological Chemistry, 273, 1165-1174.
104. Deleu, L., Fuks, F., Spitkovsky, D., Hörlein, R., Faisst, S. and Rommelaere, J. (1998)
Opposite transcriptional effects of cyclic-AMP-responsive elements in confluent or
p27 KIP -overexpressing cells versus serum-starved or growing cells.
Molecular and Cellular Biology, 18, 409-419.
105. Cziepluch, C., Kordes, E., Poirey, R., Grewenig, A., Rommelaere, J. and
Jauniaux, J.-C. (1998)
Identification of a novel cellular TPR-containing protein, SGT, that interacts with the
non-structural protein NS1 of parvovirus H-1.
Journal of Virology, 72, 4149-4156.
106. Kordes, E., Savelyeva, L., Schwab, M., Rommelaere, J., Jauniaux, J.C.
and Cziepluch, C. (1998)
Isolation and characterization of human SGT, and identification of homologues in S. cerevisiae and C. elegans.
Genomics, 52, 90-94.
107. Nüesch, J.P.F., Corbau, R., Tattersall, P. and Rommelaere, J. (1998)
Biochemical activities of minute virus of mice non-structural protein NS1 are modulated in vitro by the phosphorylation state of the polypeptide.
Journal of Virology, 72, 8002-8012.
108. Rayet, B., Lopez-Guerrero, J.-A., Rommelaere, J. and Dinsart, C. (1998).
Induction of programmed cell death by parvovirus H-1 in U937 cells: connection with the TNF* signalling pathway.
Journal of Virology, 72, 8893-8903.
109. Nüesch, J.P.F., Dettwiler, S., Corbau, R. and Rommelaere, J. (1998)
Replicative functions of minute virus of mice NS1 protein are regulated in vitro by phosphorylation through protein kinase C.
Journal of Virology, 72, 9966-9977.
110. Gu, Z.N., Kuntz-Simon, G., Rommelaere, J. and Cornelis, J. (1999)
Oncogenic transformation-dependent expression of a transcription factor NF-Y subunit.
Molecular Carcinogenesis, 24, 294-299.
111. Kuntz-Simon, G., Bashir, T., Rommelaere, J. and Willwand, T. (1999)
Neoplastic transformation-associated stimulation of the in vitro resolution of concatemer junction fragments from minute virus of mice DNA.
Journal of Virology, 73, 2552-2558.
112. Deleu, L., Pujol, A., Faisst, S. and Rommelaere, J. (1999)
Activation of promoter P4 of the autonomous parvovirus minute virus of mice (MVM) at the early S phase is required for productive infection.
Journal of Virology, 73, 3877-3885.
113. Kestler, J., Neeb, B., Struyf, S., Van Damme, J., Cotmore, S.F., D’Abramo, A., Tattersall, P., Rommelaere, J., Dinsart, C. and Cornelis, J.J. (1999)
Cis-requirements for the efficient production of recombinant DNA vectors based on
autonomous parvoviruses.
Human Gene Therapy, 10, 1619-1632.
114. Corbau, R., Salomé, N., Rommelaere, J. and Nüesch, J.P.F (1999)
Phosphorylation of the viral non-structural protein NS1 during MVMp infection of A9 cells.
Virology, 259, 402-415.
115. Bodendorf, U., Cziepluch, C., Jauniaux, J.-C., Rommelaere, J. and Salomé, N. (1999)
Nuclear export factor CRM1 interacts with the non-structural protein NS2 from parvovirus minute virus of mice.
Journal of Virology, 73, 7769-7779.
116. Dettwiler, S., Rommelaere, J. and Nüesch, J.P.F. (1999)
DNA unwinding functions of minute virus of mice NS1 protein are modulated specifically by the lambda isoform of protein kinase C.
Journal of Virology, 73, 7410-7420.
117. Ran, Z.H., Rayet, B., Rommelaere, J. and Faisst, S. (1999)
Parvovirus H-1-induced cell death: influence of intracellular NAD consumption on the regulation of necrosis and apoptosis.
Virus Research, 65, 161-174.
118. Perros, M., Fuks, F., Kherrouche, Z. and Rommelaere, J. (1999)
Atypical nucleoprotein complexes mediate CRE-dependent regulation of the early promoter of minute virus of mice.
Journal of General Virology, 80, 3267-3272.
119. Giese, N., De Martino, L., Haag, A., Dinsart, C., Cornelis, J.J and Rommelaere, J. (2000) Autonomous parvovirus-based vectors: potential for the gene therapy of cancer.
In: "Targeting of Drugs: Strategies for Gene Constructs and Delivery”, eds. G. Gregoriadis and B. McCormack. IOS Press, Amsterdam, pp.34-52.
120. Haag, A., Menten, P., Van Damme, J., Dinsart, C., Rommelaere, J. and Cornelis, J.J. (2000)
Highly efficient transduction and expression of cytokine genes into human tumor cells by means of autonomous parvovirus vectors: generation of antitumor responses in recipient mice.
Human Gene Therapy, 11, 597-609.
121. Cziepluch, C., Lampel, S., Grewenig, A., Grund, C., Lichter, P. and Rommelaere, J. (2000)
H-1 parvovirus associated replication (H1PAR)bodies: a distinct virus-induced
nuclear structure.
Journal of Virology, 74, 4807-4815.
122. Bashir, T., Hörlein, R., Rommelaere, J. and Willwand, K. (2000)
Cyclin A activates the DNA polymerase -dependent elongation machinery in vitro: a parvovirus DNA replication model.
Proceedings of the National Academy of Sciences USA, 97, 5522-5527.
123. Haag, A., Wayss, K., Rommelaere, J. and Cornelis, J.J. (2000)
Experimentally-induced infection with autonomous parvoviruses, minute virus of mice and H-1, in the African multimammate mouse (Mastomys coucha).
Comparative Medicine, 50, 613-621.
124. Corbau, R., Duverger, V., Rommelaere, J. and Nüesch, J.P.F. (2000)
Regulation of MVM NS1 by protein kinase C: impact of mutagenesis at consensus phosphorylation sites on replicative functions and cytopathic effects.
Virology, 278, 151-167.
125. Moehler, M., Blechacz, B., Weiskopf, N., Zeidler, M., Stremmel, W., Rommelaere, J.,
Galle, P.R. and Cornelis, J.J (2001)
Effective infection, apoptotic killing and gene transfer of human hepatoma cells but not
primary hepatocytes by parvovirus H-1 and derived vectors.
Cancer Gene Therapy, 8, 158-167.
126. Wetzel, K., Menten, P., Opdenakker, G., Van Damme, J., Gröne, H.J., Giese, N.,
Vecchi, A., Sozzani, S., Cornelis, J.J., Rommelaere, J. and Dinsart, C. (2001)
Transduction of human MCP-3 by a parvoviral vector induces leukocyte infiltration and
reduces growth of human cervical carcinoma cell xenografts.
The Journal of Gene Medicine, 3, 326-337.
127. Bashir, T., Rommelaere, J. and Cziepluch, C. (2001)
In vivo accumulation of cyclin A and cellular replication factors in autonomous parvovirus
MVM-associated replication bodies.
Journal of Virology, 75, 4394-4398.
128. Nüesch, J.P.F., Christensen, J. and Rommelaere, J. (2001)
Initiation of MVM DNA replication is regulated at the level of origin unwinding by atypical
PKC phosphorylation of NS1.
Journal of Virology, 75, 5730-5739.
129. Deleu, L., Pujol, A., Nüesch, J.P.F. and Rommelaere, J. (2001)
Inhibition of transcription-regulating properties of non structural protein 1 (NS1) of parvovirus minute virus of mice by a dominant negative form of NS1.
Journal of General Virology, 82, 1929-1934.
130. Olijslagers, S., Dege, A.Y., Dinsart, C., Voorhoeve, M., Rommelaere, J., Noteborn, M.H.M. and Cornelis, J.J. (2001)
Potentiation of a recombinant oncolytic parvovirus by expression of apoptin.
Cancer Gene Therapy, 8, 958-965.
131. Raykov, Z., Legrand, V., Homann, H.E. and Rommelaere, J. (2002)
Transient suppression of transgene expression by means of antisense oligonucleotides: a method for the production of toxin-transducing recombinant viruses.
Gene Therapy, 9, 358-362.
132. Giese, N.A., Raykov, Z., De Martino, L., Vecchi, A., Sozzani, S., Dinsart, C., Cornelis, J.J. and Rommelaere, J. (2002)
Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the IP-10 chemokine into immunocompetent mice.
Cancer Gene Therapy, 9, 432-442.
133. Willwand, K., Moroianu, A., Hörlein, R., Stremmel, W. and Rommelaere, J. (2002)
Specific interaction of the nonstructural protein NS1 of minute virus of mice (MVM) with
[ACCA]2 motifs in the center of the right-end MVM DNA palindrome induces hairpin-primed viral DNA replication.
Journal of General Virology ,83, 1659-1664.
134. Eichwald, V., Daeffler, L., Klein, M., Rommelaere, J. and Salomé, N. (2002)
The NS2 proteins of parvovirus minute virus of mice are required for efficient nuclear egress
of progency virions in mouse cells.
Journal of Virology, 76, 10307-10319.
135. Brown, C.S., DiSumma, F., Rommelaere, J., Dege, A.Y., Cornelis, J.J., Dinsart, C. and Spaan, W.J.M. (2002).
Production of recombinant H-1 parvovirus stocks devoid of replication-competent viruses.
Human Gene Therapy, 13, 2135-2145.
136. Nüesch, J.P.F., Lachmann, S., Corbau, R. and Rommelaere, J. (2003)
Regulation of minute virus of mice NS1 replicative functions by atypical PKC in vivo.
Journal of Virology, 77, 433-442.
137. Wrzesinski, C., Tesfay, L., Salomé, N., Jauniaux, J.C., Rommelaere, J., Cornelis, J. and
Dinsart, C. (2003)
Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and identify a DNA sequence that restricts parvovirus H-1 in mouse cells.
Journal of Virology, 77, 3851-3858.
138. Malerba, M., Daeffler, L., Rommelaere, J. and Iggo, R.D. (2003)
Replicating parvoviruses which target colon cancer cells.
Journal of Virology, 77, 6683-6691.
139. Moehler, M., Zeidler, M., Schede, J., Rommelaere, J., Galle, P.R., Cornelis, J.J. and Heike, M. (2003)
Oncolytic parvovirus H-1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells.
Cancer Gene Therapy, 10, 477-480.
140. Lachmann, S., Rommelaere, J. and Nüesch, J.P.F. (2003)
Novel PKC is required to activate replicative functions of the major non-structural protein NS1 of minute virus of mice.
Journal of Virology, 77, 8048-8060.
141. Daeffler, L., Hoerlein, R., Rommelaere, J. and Nüesch, J.P.F. (2003)
Modulation of minute virus of mice cytotoxic activities through site-directed mutagenesis
within the NS-coding region.
Journal of Virology, 77, 12466-12478.
142. Raykov, Z., Balboni, G., Aprahamian, M. and Rommelaere, J. (2004)
Carrier cell-mediated delivery of oncolytic parvoviruses for targeting metastases.
International Journal of Cancer, 109, 742-749.
143. Winnefeld, M., Rommelaere, J. and Cziepluch, C. (2004)
The human small glutamine-rich TPR-containing protein (h SGT) is required for
progress through cell division.
Experimental Cell Research, 293, 43-57.
144. Herrero y Calle, M., Cornelis, J.J., Herold-Mende, C., Rommelaere, J., Schlehofer, J.R.
and Geletneky, K. (2004)
Parvovirus H-1 infection of human glioma cells leads to complete viral replication and
efficient cell killing.
International Journal of Cancer, 109, 76-84.
145. Lang, S.I., Boelz, S., Stroh-Dege, A.Y., Rommelaere, J., Dinsart, C. and Cornelis, J.J.
(2005)
The infectivity and lytic activity of minute virus of mice wild type and derived vector
particles are strikingly different.
Journal of Virology, 79 , 289-298.
146. Li, J.- H., Werner, E., Hergenhahn, M., Poirey, R., Luo Z.-Y., Rommelaere,J. and Jauniaux, J.-C. (2005).
Expression profiling of human hepatoma cells reveals global repression of genes involved
in cell proliferation, growth and apoptosis upon infection with parvovirus H-1.
Journal of Virology, 79, 2274-2286.
147. Raykov, Z., Savelieva, L., Balboni, G., Giese, T., Rommelaere, J. and Giese, N.A. (2005)
B1 lymphocytes and myeloid dendritic cells in lymphoid organs are preferential extratumoral sites of parvovirus MVMp expression.
Journal of Virology, 79, 3517 - 3524.
148. Nüesch, J.P.F., Lachmann, S. and Rommelaere, J. (2005)
Selective alterations of the host cell architecture upon infection with parvovirus minute
virus of mice.
Virology, 331, 159-174.
149. Moehler, M.H., Zeidler, M., Wilsberg, V., Cornelis, J.J., Woelfel, T., Rommelaere, J., Galle, P.R. and Heike, M. (2005)
Parvovirus H1-induced tumor cell death enhances human immune response in vitro via increased phagocytosis, maturation and cross-presentation by dendritic cells.
Human Gene Therapy, 16, 996-1005
150. Liu, J., Ran Z.H., Xiao, S.D. and Rommelaere, J. (2005)
Changes in gene expression profiles induced by parvovirus H-1 in human gastric cancer cells.
Chinese Journal of Digestive Diseases, 6, 72-81.
151. Geletneky, K., Herrero y Calle, M., Rommelaere, J. and Schlehofer, J.R. (2005)
Oncolytic potential of rodent parvoviruses for cancer therapy in humans: a brief review.
Journal of Veterinary Medicine B, 52, 327 – 330.
152. Marchini, A., Daeffler, L., Marttila, T., Schneider, K.U., Blaschke, R.J., Schnölzer, M., Rommelaere, J. and Rappold, G. (2006).
Phosphorylation on Ser 106 modulates the cellular functions of the SHOX homeodomain protein.
Journal of Molecular Biology, 355, 590-603.
153. Mancini, A., Borrelli, A., Schiattarella, A., Fasano, S., Occhiello, A., Pica, A., Tommasino, M., Nüesch, J.P.F. and Rommelaere, J. (2006)
Tumor suppressive activity of a variant isoform of Mn superoxide dismutase released by a human liposarcoma cell line.
International Journal of Cancer, 119, 932-943.
154. Nüesch, J.P.F. and Rommelaere, J. (2006)
NS1 interaction with CKII: a novel protein complex mediating parvovirus-induced cytotoxicity.
Journal of Virology, 80, 4729-4739.
155. Abschuetz, A., Kehl, T., Geibig R., Leuchs, B., Rommelaere, J. and Regnier-Vigouroux, A. (2006).
The oncolytic murine autonomous parvovirus, a candidate vector for glioma gene therapy, is innocuous to normal and immunocompetent mouse glial cells.
Cell and Tissue Research, 325, 423-436.
156. Lang, S.I., Giese, N.A., Rommelaere, J., Dinsart, C. and Cornelis, J.J. (2006)
Humoral immune responses against minute virus of mice vectors.
The Journal of Gene Medicine, 8, 1141-1150.
157. Winnefeld, M., Grewenig, A. Schnölzer, M., Spring, H., Knoch, T.A., Gan, E.C., Rommelaere, J. and Cziepluch, C. (2006)
Human SGT interacts with Bag-6/Bat-3/Scythe, and cells with reduced levels of either protein display persistence of few misaligned chromosomes and mitotic arrest.
Experimental Cell Research, 312, 2500-2514.
158. Wetzel, K., Struyf, S., Van Damme, J., Kayser, T., Vecchi, A., Sozzani, S., Rommelaere, J., Cornelis, J.J. and Dinsart, C. (2007)
MCP-3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells.
International Journal of Cancer, 120, 1364-1371.
159. Raykov, Z., Grekova, S., Galabov, A.S., Balboni, G., Koch, U., Aprahamian, M. and Rommelaere, J. (2007)
Combined oncolytic and vaccination activities of parvovirus H-1 in a metastatic tumor model.
Oncology Reports, 17, 1493-1499.
160. Di Piazza, M., Mader, C., Geletneky, K., Herrero y Calle, M., Weber, E., Schlehofer,J., Deleu, L. and Rommelaere, J. (2007)
Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells.
Journal of Virology, 81, 4186-4198.
161. Nüesch, J.P.F. and Rommelaere, J. (2007)
A viral adaptor protein modulating Casein Kinase II activity induces cytopathic effects in permissive cells.
Proceedings of the National Academy of Sciences USA, 104, 12482-12487.
162. Angelova, A., Galabov, A.S., Rommelaere, J. and Raykov, Z. (2007)
Antitumour effects of combined radio-and parvovirotherapy in N-Ras-positive tumour cells.
Comptes Rendus de l’Académie Bulgare des Sciences, 60, 879-882.
163. Lachmann, S., Bär, S., Rommelaere, J. and Nüesch, J.P.F. (2008)
Parvovirus interference with intracellular signalling: mechanism of PKC activation in MVM-infected A9 fibroblasts.
Cellular Microbiology, 10, 755-769.
164. Krüger, L., Eskerski, H., Dinsart, C., Cornelis, J., Rommelaere, J., Haberkorn, U. and Kleinschmidt, J.A. (2008)
Augmented transgene expression in transformed cells using a parvoviral hybrid vector.
Cancer Gene Therapy, 15, 252-267.
165. Raykov, Z., Grekova, S., Leuchs, B., Aprahamian, M. and Rommelaere, J. (2008)
Arming parvoviruses with CpG motifs to improve their oncosuppressive capacity.
International Journal of Cancer, 122, 2880-2884.
166. Sieben, M., Herzer, K., Zeidler, M., Heinrichs, V., Leuchs, B., Schuler, M., Cornelis, J.J., Galle, P.R., Rommelaere, J. and Moehler, M. (2008)
Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein.
World Journal of Gastroenterology, 14, 3819-3828.
167. Baer, S., Daeffler, L., Rommelaere, J. and Nüesch, J.P.F. (2008)
Vesicular egress of non-enveloped lytic parvoviruses depends on gelsolin functioning.
PLoS Pathogens, 4 (8), e1000126, DOI:10.1371/1000126.
168. Mancini, A., Borrelli, A., Schiattarella, A., Aloj, L., Aurilio, M., Morelli, F., Pica, A., Occhiello, A., Lorizio, R., Mancini, R., Sica, A., Mazzarella, L., Sica, F., Grieco, P., Novellino, E., Pagnozzi, D., Pucci, P. and Rommelaere, J. (2008)
Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as anticancer agent.
International Journal of Cancer, 123, 2684-2695.
169. Enderlin, M., Kleinmann, E.V., Struyf, S., Buracchi, C., Vecchi, A., Kinscherf, R., Kiessling, F., Paschek, S., Sozzani, S., Rommelaere, J., Cornelis, J.J., Van Damme, J. and Dinsart, C. (2009)
TNF- and the IFN-inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act in synergy to induce antitumor effects in mouse glioblastoma.
Cancer Gene Therapy, 16, 149-160.
170. Angelova, A., Aprahamian, M., Grekova, S., Hajri, A., Leuchs, B., Giese, N., Herrmann, A., Dinsart, C., Balboni, G., Rommeleare, J* and Raykov, Z*. (2009)
Improvement of gemcitabine-based therapy of pancreatic carcinoma by means of oncolytic parvovirus H-1PV.
Clinical Cancer Research, 15, 511-519.
171. Raykov, Z., Georgieva, P., Angelova, A., Galabov, A. and Rommelaere, J. (2009)
Anticancer effects of an oncolytic parvovirus combined with nonconventional therapeutics on pancreatic carcinoma cell lines.
Acta Virologica, 53, 57-60.
172. Nüesch, J.P.F., Baer, S., Lachmann, S. and Rommelaere, J. (2009)
Ezrin-Radixin-Moesin family proteins are involved in parvovirus replication and spreading.
Journal of Virology, 83, 5854-5863.
173. Angelova, A., Aprahamian, M., Balboni, G., Delecluse, H.-J., Feederle, R., Kiprianova, I., Grekova, S., Galabov, A.S., Witzens-Harig, M., Ho, A.D., Rommelaere, J.* and Raykov, Z.* (2009)
Oncolytic rat parvovirus H-1PV, a candidate for the treatment of human lymphoma: in vitro and in vivo studies.
Molecular Therapy, 17, 1164-1172.
174. Grekova, S., Zawatzky, R., Hoerlein, R., Cziepluch, C., Mincberg, M., Davis, C., Rommelaere, J. and Daeffler, L. (2010)
Activation of an antiviral response in normal but not transformed mouse cells: a new determinant of minute virus of mice (MVMp) oncotropism.
Journal of Virology, 84, 516-531.
175. Dempe, S., Stroh-Dege, A.Y., Schwarz, E., Rommelaere, J. and Dinsart, C. (2010)
SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H-1PV.
International Journal of Cancer, 126, 2914-2927.
176. Geletneky, K., Hartkopf, A.D., Krempien, R., Rommelaere, J. and Schlehofer, J.R.(2010)
Improved killing of human high-grade glioma cells by combining ionizing radiation with oncolytic parvovirus H-1 infection.
Journal of Biomedicine and Biotechnology, 2010, e 3507448, DOI:10.1155/350748
177. Hristov, G., Krämer, M., Li, J-W., El-Andaloussi, N., Mora,R., Daeffler, L., Zentgraf, H., Rommelaere, J. and Marchini, A. (2010)
Through its non-structural protein NS1, parvovirus H-1 induces apoptosis via accumulation of reactive oxygen species.
Journal of Virology, 84, 5909-5922.
178. Lacroix,J., Li, J., Leuchs, B., Deubzer, H., Kulozik, A.E., Rommelaere,J., Schlehofer, J.R. and Witt, O. (2010)
Parvovirus H-1 selectively induces cytotoxic effects on human neuroblastoma cells.
International Journal of Cancer, 127, 1230-1239.
179. Geletneky, K., Kiprianova, I., Ayache, A., Koch, R., Herrero Y Calle, M., Deleu, L., Sommer, C., Thomas, N., Rommelaere, J.* and Schlehofer, J.R.* (2010)
Regression of advanced rat and human gliomas by local or systemic treatment with oncolytic parvovirus H-1 in rat models.
Neuro-Oncology, 12, 804-814.
180. Geletneky, K., Hartkopf, A.D., Krempien, R., Rommelaere, J. and Schlehofer, J.R. (2010).
Therapeutic implications of the enhanced short and long-term cytotoxicity of radiation treatment followed by oncolytic parvovirus H-1 infection in high-grade glioma cells.
Bioengineered Bugs, 1, 429-433.
181. Decrion-Barthod, A.-Z., Bosset, M., Plissonnier, M.-L., Marchini, A., Nicolier, M., Launay, S., Prétet, J.-L., Rommelaere, J. and Mougin, C. (2010)
Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells.
Anticancer Research, 30, 4049-4061.
182. Grekova, S.P., Aprahamian, M., Giese, N.A., Schmitt, S., Giese, T., Falk, C.S., Daeffler, L., Cziepluch, C., Rommelaere, J. and Raykov, Z. (2010)
Immune cells participate in the oncosuppressive activity of parvovirus H-1PV and are activated as a result of their abortive infection with this agent.
Cancer Biology and Therapy, 10, 1280-1289.
183. Bhat, R., Dempe, S., Dinsart, C. and Rommelaere, J. (2011)
Enhancement of NK cell anti-tumour responses using an oncolytic parvovirus.
International Journal of Cancer, 128, 908-919.
184. El-Andaloussi, N., Endele, M., Leuchs, B., Bonifati, S., Kleinschmidt, J., Rommelaere, J. and Marchini, A. (2011)
Novel adenovirus-based helper system to support production of recombinant parvovirus.
Cancer Gene Therapy, 18, 240-249.
185. Alkassar, M., Gaertner, B., Roemer, K., Graesser, F., Rommelaere, J., Kaestner, L., Haeckel, I. and Graf, N. (2011)
The combined effects of oncolytic reovirus plus Newcastle disease virus and reovirus plus parvovirus on U87 and U373 cells in vitro and in vivo.
Journal of Neurooncology, 104, 715-727.
186. Kiprianova, I., Thomas, N., Ayache, A., Fischer, M., Leuchs, B., Klein, M., Rommelaere, J. and Schlehofer, J.R. (2011)
Regression of glioma in rat models by intranasal application of parvovirus H-1.
Clinical Cancer Research, 17, 5333-5342.
187. Grekova, S., Aprahamian, M., Daeffler, L., Leuchs, B., Angelova, A., Giese, T., Galabov, A.S., Heller, A., Giese, N.A., Rommelaere, J. and Raykov, Z. (2011)
Interferon-gamma improves the vaccination potential of oncolytic parvovirus H-1PV for the treatment of peritoneal carcinosis in pancreatic cancer.
Cancer Biology and Therapy, 12, 889-895.
188. Moehler, M., Sieben, M., Roth, S., Springsguth, F., Leuchs, B., Zeidler, M., Dinsart, C., Rommelaere, J. and Galle, P.R. (2011)
Activation of the human immune system by chemotherapeutic or targeted agents combined with the oncolytic parvovirus H-1.
BioMed Central Cancer, 11: 464, DOI : 10.1186/1471-2407-11-464.
189. El-Andaloussi, N., Leuchs, B., Bonifati, S., Rommelaere, J. and Marchini, A. (2012)
Efficient recombinant parvovirus production with the help of adenovirus-derived systems.
Journal of Visualized Experiments, 62, e3518, DOI: 10.3791/3518.
190. Allaume, X., El-Andaloussi,N., Leuchs, B., Bonifati, S., Kulkarni, A., Marttila, T., Kaufmann, J.K., Nettelbeck, D.M., Kleinschmidt, J., Rommelaere, J. and Marchini, A. (2012)
Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid.
Journal of Virology, 86, 3452-3465.
191. Moralès, O., Richard, A., Martin, N., Mrizak, D., Sénéchal, M., Pancré, V., Rommelaere, J., Caillet-Fauquet, P., de Launoit, Y and Delhem, N. (2012)
Activation of a helper and not regulatory human CD4 + T cell response by oncolytic H-1 parvovirus.
PLoS ONE, 7, e32197, DOI: 10.1371/0032197.
192. Geletneky, K., Huesing, J., Rommelaere, J., Schlehofer, J.R., Dahm, M., Krebs, O., von Knebel Doeberitz, M., Huber, B. and Hajda, J. (2012)
Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol.
BioMed Central Cancer, 12: 99, DOI: 10.1186/1471-2407-12-99.
193. Grekova, S.P., Raykov, Z., Zawatzky, R., Rommelaere, J. and Koch, U. (2012)
Activation of a glioma-specific immune response by oncolytic minute virus of mice infection.
Cancer Gene Therapy, 19, 468-475.
194. Weiss, N., Stroh-Dege, A., Rommelaere, J., Dinsart, C. and Salomé, N. (2012)
An in-frame deletion in the NS protein-coding sequence of parvovirus H-1PV efficiently stimulates export and infectivity of progeny virions.
Journal of Virology, 86, 7554-7564.
195. Dempe, S., Lavie, M., Struyf, S., Bhat, R., Verbeke, H., Paschek, S., Berghmans, N., Geibig, R., Rommelaere, J., Van Damme, J. and Dinsart, C. (2012)
Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leukocyte recruitment.
Cancer Immunology, Immunotherapy, 61, 2113-2123.
196. Sánchez-Martinez, C., Grueso, E., Carroll, M., Rommelaere,J. and Almendral del Rio, J.M. (2012)
Essential role of the unordered VP2 n-terminal domain of the parvovirus MVM capsid in nuclear assembly and endosomal enlargement of the virion fivefold channel for cell entry.
Virology, 432, 45-56
197. Wang, Y.Y., Liu, J., Zheng, Q., Ran, Z.H., Salomé, N., Vogel, M., Rommelaere, J., Xiao, S.D. and Wang, Z. (2012)
Effect of the parvovirus H-1 non-structural protein NS1 on the tumorigenicity of human gastric cancer cells.
Journal of Digestive Diseases, 13, 366-373.
198. El-Andaloussi, N., Bonifati, S., Kaufmann, J.K., Mailly, L., Daeffler, L., Deryckere, F., Nettelbeck, D.M., Rommelaere, J. and Marchini, A. (2012)
Generation of an adenovirus-parvovirus chimera with enhanced oncolytic potential.
Journal of Virology, 86, 10418-10431.
199. Raykov, Z., Grekova, S., Hörlein, R., Leuchs, B., Giese, T., Giese, N.A., Rommelaere, J., Zawatzky, R. and Daeffler, L. (2013)
TLR-9 contributes to the antiviral innate immune sensing of rodent parvoviruses MVMp and H-1PV by normal human immune cells.
PLOS ONE, 8, e55086, DOI: 10.1371/0055086.
200. Bhat, R. and Rommelaere, J. (2013)
NK cell-dependent killing of colon carcinoma cells is mediated by natural cytotoxicity receptors (NCRs) and stimulated by an oncolytic virus.
BioMed Central Cancer, 13: 367, DOI: 10.1186/1471-2407-13-367.
201. Bär, S., Rommelaere, J. and Nüesch, J.P.F. (2013)
Vesicular transport of progeny parvovirus particles through ER and Golgi regulates maturation and cytolysis.
PLoS Pathogens, 9: 9, e1003605, DOI: 10.1371/journal.ppat.1003605.
202. Li, J.W., Bonifati, S., Hristov, G., Marttila, T., Valmary-Degano, S., Stanzel, S., Schnölzer, M., Mougin, C., Aprahamian, M., Grekova, S.P., Raykov, Z., Rommelaere, J. and Marchini, A. (2013)
Synergistic combination of valproic acid and oncolytic parvovirus H-1PV as a potential therapy against cervical and pancreatic carcinomas.
EMBO Molecular Medicine, 5, 1537-1555.
203. Lavie, M., Struyf, S., Stroh-Dege, A., Rommelaere, J., Van Damme, J. and Dinsart, C. (2013)
Capacity of wild-type and chemokine-armed parvovirus H-1PV for inhibiting neo-angiogenesis.
Virology, 447, 221-232.
204. Lacroix, J., Schlund, F., Adolph, K., Leuchs, B., Bender, S., Hielscher, T., Pfister, S.M., Witt, O., Rommelaere, J., Schlehofer, J.R. and Witt, H. (2014)
Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis.
International Journal of Cancer, 134, 703-716.
205. Angelova, A., Grekova, S., Heller, A., Kuhlmann, O., Soyka, E., Giese, T., Aprahamian, M., Bour, G., Rüffer, S., Cziepluch, C., Daeffler, L., Rommelaere, J., Werner, J., Raykov, Z. and Giese, N. (2014).
Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer.
Journal of Virology, 88, 5263-5276.
206. Grekova, S.P., Aprahamian, M., Giese, N.A., Bour, G., Giese, T., Grewenig, A., Leuchs, B., Hörlein, R., Heller, A., Angelova, A.L., Rommelaere, J. and Raykov, Z. (2014)
Genomic CpG enrichment of oncolytic parvoviruses as a potent anticancer vaccination strategy for the treatment of pancreatic adenocarcinoma.
Journal of Vaccines & Vaccination, 5: 227, DOI: 10.4172/2157-7560.1000227.
207. Tal, S., Mincberg, M., Rostovsky, I., Rommelaere, J., Salomé, N. and Davis, C. (2014).
The Minute Virus of Mice NS2 proteins are not essential for productive infection of embryonic murine cells in utero.
Virology, 468-470, 631-636.
208. Geletneky, K., Leoni, A.-L., Pohlmeyer-Esch, G., Loebhard, S., Baetz, A., Leuchs, B., Roscher, M., Hoefer, C., Jochims, K., Dahm, M., Huber, B., Rommelaere, J., Krebs, O. and Hajda, J. (2015).
Pathology, organ distribution and immune response after single and repeated intravenous injection of rats with clinical-grade parvovirus H-1.
Comparative Medicine, 65, 23-35.
209. Geletneky, K., Leoni, A.-L., Pohlmeyer-Esch, G., Loebhard, S., Leuchs, B., Hoefer, C., Jochims, K., Dahm, M., Huber, B., Rommelaere, J., Krebs, O. and Hajda, J. (2015)
Bioavailability, biodistribution and CNS toxicity of clinical-grade parvovirus H-1 after intravenous and intracerebral injection in rats.
Comparative Medicine, 65, 36-45.
210. Bär, S., Rommelaere, J. and Nüesch, J.P.F. (2015)
PKCη/Rdx-driven phosphorylation of PDK1: a novel mechanism promoting cancer cell survival and permissiveness for parvovirus-induced lysis.
PLoS Pathogens, 11: 3, e1004703, DOI: 10.1371/journal.ppat.1004703.
211. Geletneky, K., Nüesch, J.P.F., Angelova, A., Kiprianova, I. and Rommelaere, J. (2015)
Double-faceted mechanism of parvoviral oncosuppression.
Current Opinion in Virology, 13, 17-24.
212. Borrelli, A., Schiattarella, A., Mancini, R., Pica, A., Pollio, M.L., Ruggiero, M.G., Bonelli, P., De Luca, V., Tuccillo, F.M., Capasso, C., Gori, E., Sanseverino, M., Carpentieri, A., Birolo, L., Pucci, P., Rommelaere, J. and Mancini, A. (2016)
A new hexapeptide from the leader peptide of rMnSOD enters cells through the oestrogen receptor to deliver therapeutic molecules.
Scientific Reports, 6: 18691, DOI: 10.1038/srep 18691.
213. Leuchs, B., Roscher, M., Müller, M., Kürschner, K. and Rommelaere, J. (2016)
Standardized large-scale H-1PV production process with efficient quality and quantity monitoring.
Journal of Virological Methods, 229, 48-59.
214. Heller, A., Angelova, A., Bauer, S., Grekova, S.P., Aprahamian, M., Rommelaere, J., Volkmar, M., Janssen, J.W.G., Bauer, N., Herr, I., Giese, T., Gaida, M.M., Hackert, T., Fritz, S. and Giese, N.A.
Establishment and characterization of a novel cell line, ASAN-PaCa, derived from human adenocarcinoma arising in intraductal papillary mucinous neoplasm of the pancreas.
Pancreas, in press.
215. Josupeit, R., Bender, S., Kern, S., Leuchs, B., Hielscher, T., Herold-Mende, C., Schlehofer, J.R., Dinsart, C., Witt, O., Rommelaere, J. and Lacroix, J. (2016).
Pediatric and adult high-grade glioma stem cell models are permissive to lytic infection with parvovirus H-1.
Viruses, 8: 138, DOI: 10.3390/v8050138.
216. Dinsart, C., Pervolaraki, K., Stroh-Dege, A., Lavie, M., Ronsse, I., Rommelaere, J., Van Damme, J., Van Raemdonck, K. and Struyf, S. (2017)
Recombinant parvoviruses armed to deliver CXCL4L1 and CXCL10 are impaired in their antiangiogenic and antitumoral effects in a Kaposi sarcoma tumor model due to the chemokines’ interference with the virus cycle.
Human Gene Therapy, in press.
217. Leuchs, B., Frehtman, V., Riese, M., Müller, M. and Rommelaere, J. (2017)
A novel scalable, robust downstream process for oncolytic rat parvovirus: isoelectric point-based elimination of empty particles.
Applied Microbiology and Biotechnology, 101, - , DOI: 10.1007/s00253-016-8071-x.

REVIEW PAPERS

1. Radman, M., Rommelaere, J. and Errera, M. (1973)
Stability and evolution of DNA from the point of view of molecular radiobiology.
In: "Physicochemical Properties of Nucleic Acids", ed. J. Duchesne. Academic Press, New York, vol.3, pp. 161-201.
2. Rommelaere, J. (1985)
Induction by damaged DNA of repair systems in cells and bacteria: Minisymposium Report
In: "Photobiology 1984", eds. J. Longworth, J. Jagger and W. Shropshire. Prager Scientific, New York, pp. 101-109.
3. Rommelaere, J. and Tattersall, P. (1990)
Oncosuppression by Parvoviruses
In : "Handbook of Parvoviruses ", ed. P. Tijssen. CRC Press, Boca Raton, vol II, pp 41-57.
4. Cornelis, J.J. and Rommelaere, J. (1990)
Parvoviral probes for cellular responses to DNA damage.
In : "Handbook of Parvoviruses ", ed. P. Tijssen. CRC Press, Boca Raton, vol II, pp 231-246.
5. Rommelaere, J. (1990)
Action anticancéreuse des parvovirus.
Médecine/Sciences, 6, 534-543.
6. Rommelaere, J. and Cornelis, J.J. (1991)
Antineoplasic activity of parvoviruses.
Journal of Virological Methods, 33, 233-251.
7. Vanacker, J.-M. and Rommelaere, J. (1995)
Non-structural proteins of autonomous parvoviruses: from cellular effects to molecular mechanisms.
Seminars in Virology, 6, 291-297.
8. Dinsart, C., Cornelis, J.J. and Rommelaere, J. (1996)
Recombinant autonomous parvoviruses: new tools for the gene therapy of cancer?
Chemistry Today, 14, 32-38.
9. Rommelaere, J., Caillet-Fauquet, P., Almendral, J.M. and Stehelin, D. (1998)
Oncosuppression by parvoviruses: assessment of its potential use for the prevention and/or therapy of human cancer.
In: "Biomedical and Health Research: Cancer Research Supported under Biomed 1", ed. S.S. Baig. IOS Press, Amsterdam, Vol. 24 , pp. 34-42.
10. Cornelis, J.J., Haag, A., Kornfeld, C., Balboni, G., Dege, A., Neeb, B., Dinsart, C. and
Rommelaere, J. (2000)
Autonomous parvovirus vectors.
In: "Viral Vectors: Basic Science and Gene Therapy", eds. A.Cid-Arregui and A. Garcia-
Carranca. BioTechniques Books, Eaton Publ., Natick, MA, pp. 97-115.
11. Rommelaere, J. and Faisst, S. (2000)
Preface.
In: "Parvoviruses: from Molecular Biology to Pathology and Therapeutic Uses", eds. S.
Faisst and J. Rommelaere. Contributions to Microbiology, Karger, Basel, vol. 4, XI-XII.
12. Rommelaere, J., Dinsart, C. and Cornelis, J. (2001)
Vecteurs parvoviraux.
In: "La Thérapie Génique", ed. O. Cohen-Haguenauer. Editions Technique & Documentation, Paris, pp. 205-216.
13. Rommelaere, J. and Cornelis, J.J (2001)
Autonomous parvoviruses.
In: "Replication-Competent Viruses for Cancer Therapy", eds. P. Hernaiz Driever and S.D. Rabkin. Monographs in Virology, Karger, Basel, vol. 22, pp. 100-129.
14. Deleu, L., Daeffler, L., Faisst, S. and Rommelaere, J. (2002)
Action oncolytique des parvovirus de rongeurs.
Virologie, 6, 29-40.
15. Rommelaere, J., Almendral, J.M., Cornelis, J.J. and Nüesch, J.P.F. (2002)
Parvovirus.
In: "The Springer Index of Viruses", eds. C.A. Tidona and G. Darai. Springer Verlag, Heidelberg, pp. 713-722.
16. Cornelis, J.J., Lang, S.I., Stroh-Dege, A.Y., Balboni, G., Dinsart, C. and
Rommelaere, J. (2004)
Cancer therapy through autonomous parvovirus-mediated gene transfer.
Current Gene Therapy, 4, 249-261.
17. Cornelis, J.J., Salomé, N., Dinsart, C. and Rommelaere, J. (2004)
Vectors based on autonomous parvoviruses: novel tools to treat cancer?
The Journal of Gene Medicine, 6, S193-202.
18. Raykov, J., Aprahamian, M., Galabov, A. and Rommelaere, J. (2004)
Oncolytic parvoviruses as tools for cancer gene therapy.
Biotechnology and Biotechnological Equipment, 18, 3-9.
19. Rommelaere, J., Giese, N., Cziepluch, C. and Cornelis, J.J. (2005)
Parvoviruses as anti-cancer agents.
In: “Virus Therapy of Human Cancers”, eds. J.G. Sinkovics and J.C. Horvath. Marcel Dekker, Inc., New York, pp. 627-675.
20. Cornelis, J.J., Deleu, L., Koch, U. and Rommelaere, J. (2006)
Parvovirus oncosuppression.
In: “Parvoviruses”, eds. J.R. Kerr, S.F. Cotmore, M.E. Bloom, R.M. Linden and C.R. Parrish.
Edward Arnold Ltd., London, pp. 365-378.
21. Rommelaere, J., Dinsart, C., Régnier-Vigouroux, A., Salomé, N. and Schlehofer, J. (2007)
Des cancers traités par des virus.
Pour la Science, Dossier N 55, 56-60.
22. Raykov, Z. and Rommelaere, J. (2008)
Potential of tumor cells for delivering oncolytic viruses.
Gene therapy, 15, 704-710.
23. Nüesch, J.P.F., Baer, S. and Rommelaere, J. (2008)
Viral proteins killing tumor cells: new weapons in the fight against cancer.
Cancer Biology and Therapy, 7, 1374-1376.
24. Nüesch, J.P.F. and Rommelaere, J. (2009)
A parvoviral adaptor protein mediating toxicity for transformed cells.
In: "Proteins Killing Tumour Cells", eds. C. Backendorf, M. Noteborn and M. Tavassoli. Research Signpost (Series on Cell Death and Disease), Transworld Research Network, Trivandrum, pp. 125-137.
25. Rommelaere, J., Geletneky, K., Angelova, A.L., Daeffler, L., Dinsart, C., Kiprijanova, I., Schlehofer, J.R. and Raykov, Z. (2010)
Oncolytic parvoviruses as cancer therapeutics.
Cytokine and Growth Factor Reviews, 21, 185-195.
26. Schlehofer, J.R. and Rommelaere, J. (2010)
The vital viruses.
Science and Technology, 7, 240-241.
27. Geletneky, K. and Rommelaere, J. (2010)
Oncolytic parvovirus for cancer of the brain: are we approaching human trials?
Future Neurology, 5, 783-785.
28. Lacroix, J., Witt, O., Schlehofer, J. and Rommelaere, J. (2010)
Therapeutic exploitation of oncolytic viruses in pediatric oncology.
Drugs of the Future, 35, 1015-1027.
29. Rommelaere, J., Almendral, J.M., Cornelis, J.J. and Nüesch, J.P.F. (2012)
Parvovirus.
In: "The Springer Index of Viruses" (2nd Edition), eds. C.A. Tidona and G. Darai. Springer Verlag, Heidelberg, pp. 1231-1241.
30. Nüesch, J.P.F., Lacroix, J., Marchini, A. and Rommelaere, J. (2012)
Molecular pathways: rodent parvoviruses: mechanisms of oncolysis and prospects for clinical cancer treatment.
Clinical Cancer Research, 18, 3516-3523.
31. Grekova, S., Rommelaere, J. and Raykov, Z. (2012)
Parvoviruses: tools to fine-tune anticancer immune responses.
OncoImmunology, 1, 1417-1419.
32. Raykov, Z., Angelova, A.L. Galabov, A.S. and Rommelaere, J. (2012)
The story of a good virus: the parvovirus in the rye?
In: ̎ New Trends in Microbiology ̎ , eds. H. Najdenski, M. Angelova and S. Stoitsova.
Bulgarian Academy of Sciences, Sofia, pp. 83-92.
33. Raykov, Z., Grekova, S.P. and Rommelaere, J. (2013)
Parvoviruses – the friendly anticancer immunomodulators.
In: ̎ Molecular Vaccines”, vol. 1, ed. M. Giese. Springer Verlag, Wien/New York, pp. 413-424.
34. Nüesch, J.P.F. and Rommelaere, J. (2014)
Tumor suppressing properties of rodent parvovirus NS1 proteins and their derivatives.
Advances in Experimental Medicine and Biology, 818, 99-124, DOI: 10.1007/978-1-4471-6458-6_5
35. Moehler, M., Goepfert, K., Heinrich, B., Breitbach, C.J., Delic, M., Galle, P.R. and Rommelaere, J. (2014)
Oncolytic virotherapy as emerging immunotherapeutic modality: potential of parvovirus H-1.
Frontiers in Oncology (Tumor Immunity), 4: 92, DOI:10.3389/fonc. 2014.00092.
36. Marchini, A., Bonifati, S., Scott, E.M., Angelova, A.L. and Rommelaere, J. (2015)
Oncolytic parvoviruses: from basic virology to clinical applications.
Virology Journal, 12: 6, DOI: 10.1186/s12985-014-0223-y.
37. Bhat, R. and Rommelaere, J. (2015)
Emerging role of NK cells in oncolytic virotherapy.
ImmunoTargets and Therapy, 2015: 4, 65-77.
38. Angelova, A.L., Geletneky, K., Nüesch, J.P.F. and Rommelaere, J. (2015)
Tumor selectivity of oncolytic parvoviruses: from in vitro and animal models to cancer patients.
Frontiers in Bioengineering and Biotechnology, 3: 55, DOI:10.3389/fbioe.2015.00055.
39. Marchini, A., Scott, E.M. and Rommelaere, J. (2016)
Overcoming barriers in oncolytic virotherapy with HDAC inhibitors and immune checkpoint blockade.
Viruses, 8:9, DOI: 10.3390/v8010009.
40. Nettelbeck, D., Ungerechts, G., Bussow, S., Leuchs, B., Holm P.S., Rommelaere J., Coffey, M., Coffin, R. and Bell, J. (2016)
Moving oncolytic viruses into the clinic - clinical grade production, purification and characterization of diverse oncolytic viruses.
Molecular Therapy-Methods&Clinical Development, 3, 16018, DOI:10.1038/mtm. 2016.18.
41. Vassaux, G., Angelova, A., Baril, P., Midoux, P., Rommelaere, J. and Cordelier, P. (2016)
The promise of gene therapy for pancreatic cancer.
Human Gene Therapy, 27, 127-133.

EDITORSHIP

Parvoviruses: from molecular biology to pathology and therapeutic uses.
In: "Contributions to Microbiology”, Vol. 4, eds. J. Rommelaere and S. Faisst. Karger AG, Basel, 2000.

PATENTS

1. Nüesch, J.P.F. and Rommelaere, J.
Parvovirus NS1 variants.
US 6,919,196 B1 (2005); Eur 1 077 260 (2010).
2. Rommelaere, J., Cornelis, J., Dinsart, C., Tattersall, P., Cotmore, S. and d’Abramo, A.
Parvovirus vectors and their use.
Eur 1 001 031 (2006); US 7,267,825 B1 (2007).
3. Daeffler, L., Nüesch, J.P.F. and Rommelaere, J.
Compositions comprising a parvovirus VP1 variant and a parvovirus NS1 protein for induction of cytolysis.
Eur 1 275 658 (2006); US 8,450,289 (2013).
4. Rommelaere, J., Cornelis, J., Dinsart, C., Schlehofer, J.R., Geletneky, K. and Herrero y Calle, M.
Use of parvovirus for brain tumor therapy.
US 7,179,456 B2 (2007).
5. Nüesch, J.P.F. and Rommelaere, J.
Fusion polypeptide suitable as a cytotoxin.
Eur 1 620 468 (2012); US 8,598,326 (2013).
6. Raykov, Z., Rommelaere, J., Giese, N. and Aprahamian, M.
Parvovirus having a CpG-enriched genome useful for cancer therapy.
Eur 2 075 003 B1 (2010); US 8,535,929B2 (2013); Can 2,710,889 (2015).
7. Rommelaere, J., Schlehofer, J., Raykov, Z., Angelova, A., Aprahamian, M., Geletneky, K., Kiprijanova, I. and Heimberger, T.
Method for cancer therapy with a parvovirus combined with chemotherapy/Parvovirus cancer therapy and combination with chemotherapy.
Eur 2 082 745 (2009), 2 227 240 B1 (2011), 2 431 045 (2013); US 8,414,883 (2013);
Jap 5269096 (2013); Can 2 710 928 (2015).
8. Aprahamian, M., Geletneky, K., Grekova, S., Kiprijanova, I., Koch, U., Raykov, Z. and Rommelaere, J.
Oncolytic virotherapy for prevention of tumor recurrence.
Au 2010256024 (2013); Eur 2 437 760 B1 (2014); Jap 5778664 (2015); Can 2 761 659 (2015).
9. Fischer, M., Geletneky, K., Kiprijanova, I., Schlehofer, J.R. and Rommelaere, J.
Method for cancer therapy based on co-administration of a parvovirus and a cytokine.
Jap 5492986 (2014).
Method for brain cancer therapy by co-administration of a parvovirus and interferon- gamma. US 9,446,099 B2 (2016).
10. Kern, A., Kürschner, K., Müller, M., Münstermann, S., Rommelaere, J. and Leuchs, B.
Antibody that binds to H-1 parvovirus.
Eur 2 332 986 B1 (2013); US 8,828,400 B2 (2014); Jap 5755239 (2015); Can 2 781 796 (2016).
11. El-Andaloussi, N., Hristov, G., Li, J-W., Marchini, A. and Rommelaere, J.
Cancer therapy with a parvovirus combined with an HDAC inhibitor.
Eur 2 547 349 B1 (2014); Au 2011229490 (2014); Jap 5718377 (2015); Can 2 793 023 (2015).
12. Endele, M., Leuchs, B., Marchini, A., Rommelaere, J. and El-Andaloussi, N.
Adenovirus-derived helper virus for enhancing recombinant parvovirus production.
Eur 2 368 903 (2014); Au 2011231998 (2015); Jap 5829265 (2015); Can 2 794 383 (2015).
13. Buechler, M., Cziepluch, C., Daeffler, L., Giese, N., Giese, T., Raykov, Z., Rommelaere, J and Werner, J.
Diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy
Jap 5725463 (2015); Au 2011247360 (2016).
14. Plotzky, C., Rommelaere, J., Thomas, N. and Nüesch, J.P.F.
Modified rodent parvovirus capable of propagating and spreading through human gliomas.
Eur 2 384 761 (2013), 2 566 491 B1 (2015); Au 2011250204 (2014); US 9,029,117 B2 (2015); Jap 5812301 (2015); Can 2 798 098 (2016).
15. Dinsart, C., Michel, N., Rommelaere, J. and Salomé, N.
Modified parvovirus having enhanced anti-tumor efficacy.
US 8,916,176 B2 (2014); Eur 2 582 796 B1 (2016).
16. Lacroix, J., Kis, Z., Rommelaere, J., Schlehofer, J., Frank-Stöhr, M. and Leuchs, B. Oncolytic virotherapy for the therapy of Ewing’s sarcoma.
Eur 2 720 702 B1 (2015); Jap 5799242 (2015); Au 2012269386; US 9,333,225 B2 (2016).
17. Allaume, X., Marchini, A., El-Andaloussi, N., Rommelaere, J. and Leuchs, B.
Retargeting of rat parvovirus H-1 PV to cancer cells through genetic engineering of its capsid.
Jap 5765790 (2015); Au 2011317846 (2015); US 9,234,183 B2 (2016); Can 2 814 235 (2016).
18. Lacroix, J., Deubzer, H., Herold-Mende, C., Kern, S., Rommelaere, J., Schlehofer, J. and Witt, O.
Use of parvovirus for eliminating cancer stem cells.
Can 2 804 540 (2015); Jap 5782511 (2015); Au 2011276134 (2015).
19. Marchini, A., Illarionova, A., Rommelaere, J. and Leuchs, B.
Modified parvovirus useful for gene silencing.
Eur 2 620 503 (2014), 2 807 259 B1 (2016); Au 2013211755 (2016); Jap 5901796 (2016).
20. El-Andaloussi, N., Marchini, A. and Rommelaere, J.
Adeno-parvovirus chimera with enhanced oncolytical potential.
Can 2 832 369 (2016); Au 2012280629 (2016); Jap 5895051 (2016); US 9,441,246 B2 (2016).
21. Kiprijanova, I., Ayache, A., Schlehofer, J., Fischer, M. and Rommelaere, J.
Parvovirus for treatment of tumours by intranasal application.
Eur 2 579 885 B1 (2016).

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