Alcohol, Toxic metabolism and DNA repair in Blood Stem cells
Table of Contents
KJ Patel - MRC Laboratory for Molecular Biology Cambridge
Sept 19, 2012
15:00 DKFZ Auditorium
Host: Andreas Trumpp
Biosketch KJ Patel
KJ Patel is Senior Scientist at the MRC Laboratory for Molecular Biology in Cambridge. He was born in Kenya and did most of his education in the UK. He initially trained as a liver transplant doctor and then chose to enter research as a PhD student with M.Neuberger at the MRC in Cambridge where his dissertation work was in immunology. He then moved from this into a postdoc with A. Venkitaraman where he made the the discovery that the BRCA2 gene product functioned in DNA repair. This lead to a group leader position in the MRC LMB in Cambridge where for the last 12 years his lab has been working on a rare human genetic illness known as Fanconi Anaemia – a condition that results in defective development and stem cell failure. The most recent work from his lab uncovers what goes wrong in FA, giving new insights into the connections between metabolism, DNA repair and stem cell function.