Publications
Table of Contents
Relevant publications by Viktor Umansky (since 2001)
1. Feuerer, M., Beckhove, P., Bai, L., Solomayer, E.-F., Bastert, G., Diehl, I.J., Pedain, C., Oberniedermayr, M., Schirrmacher, V., and Umansky, V. Therapy of human tumors in NOD/SCID mice with patient derived re-activated memory T cells from bone marrow. Nature Med., 7: 452-458, 2001.
2. Feuerer, M., Rocha, M., Bai, L., Umansky, V., Solomayer, E.-F., Bastert, G., Diehl, I.J., and Schirrmacher, V. Enrichment of memory T cells and other profound changes in the immune compartment of bone marrow from untreated breast cancer patients. Int.J.Cancer, 92: 96-105, 2001.
3. Bai, L., Feuerer, M., Beckhove, P., Umansky, V. and Schirrmacher, V. Generation of dendritic cells from human bone marrow mononuclear cells: Advantages for clinical application in comparison to peripheral blood monocyte derived cells. Int. J. Oncol., 20: 247-253, 2002.
4. Schirrmacher, V., Feuerer, M., Beckhove, P., Ahlert, T., and Umansky, V. T cell memory, anergy and immunotherapy in breast cancer. J. Mammary Gland Biol. Neoplasia, 7: 201-208, 2002.
5. Bai, L., Beckhove, P., Feuerer, M., Umansky, V., Choi, C., Schütz, F., Solomayer, E.-F., Diel, I.J., and Schirrmacher, V. Cognate interactions between memory T cells and tumor antigen-presenting dendritic cells from bone marrow of breast cancer patients: Bidirectional cell stimulation, survival and antitumor activity in vivo. Int. J. Cancer, 103: 73-83, 2003.
6. Solomayer, E.-F., Feuerer, M., Bai, L., Umansky, V., Beckhove, P., Meyberg, G.C., Bastert, G., Schirrmacher, V., and Diehl, I.J. Influence of adjuvant hormone therapy and chemotherapy on the immune system analyzed in the bone marrow of patients with breast cancer. Clin. Cancer Res., 9: 174-180, 2003.
7. Beckhove, P., Schütz, F., Diehl, I.J., Solomayer, E.-F., Bastert, G., Förster, J., Oberniedermayr, M., Feuerer, M., Bai, L., Sinn, H.-P., Umansky, V. and Schirrmacher, V. Efficient engraftment of human primary breast cancer transplants in NOD/SCID mice. Int. J. Cancer, 105: 444-453, 2003.
8. Schirrmacher, V., Feuerer, M., Fournier, P., Ahlert, T., Umansky, V., and Beckhove, P. T-cell priming in bone marrow: the potential for long-lasting protective anti-tumor immunity. Trends Mol. Med., 9: 526-534, 2003.
9. Feuerer, M., Beckhove, P., Garbi, N., Mahnke, Y., Limmer, A., Hommel, M., Hämmerling, G., Kyewski, B., Hamann, A., Umansky, V., and Schirrmacher, V. Bone marrow as a priming site for T-cell responses to blood-borne antigen. Nature Med., 9: 1151-1157, 2003.
10. Feuerer, M., Beckhove, P., Mahnke, Y., Hommel, M., Kyewski, B., Hamann, A., Umansky, V., and Schirrmacher, V. Bone marrow microenvironment facilitating dendritic cell: CD4 T cell interactions and maintenance of CD4 memory. Int. J. Oncol., 25: 867-876, 2004.
11. Beckhove, P., Feuerer, M., Dolenc, M., Schuetz, F., Choi, C., Sommerfeldt, N., Schwendemann, J., Ehlert, K., Altevogt, P., Bastert, G., Schirrmacher, V., and Umansky, V. Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors. J. Clin. Invest., 114: 67-76, 2004.
12. Muller-Berghaus, J., Ehlert, K., Ugurel, S., Umansky, V., Bucur, M., Schirrmacher, V., Beckhove, P., and Schadendorf, D.. Melanoma-reactive T cells in the bone marrow of melanoma patients: association with disease stage and disease duration. Cancer Res., 66: 5997-6001, 2006.
13. Bazhin, A.V., Schadendorf, D., Willner, N., De Smet, C., Heinzelmann, A., Tikhomirova, N.K., Umansky, V., Philippov, P.P., and Eichmuller, S.B. Photoreceptor proteins as cancer-retina antigens. Int. J. Cancer, 120: 1268-1276, 2007.
14. Schirrmacher, V., Beckhove, P., Fournier, P., and Umansky V. Second international conference on cancer vaccines/adjuvants/delivery for the next decade (CVADD): Heidelberg, Germany, 10-12 October 2007. Cancer Immunol. Immunother., 2008 57: 1421-1427.
15. Umansky, V., Abschuetz, O., Osen, W., Ramacher, M., Zhao, F., Kato, M., and Schadendorf, D. Melanoma specific memory T cells are functionally active in ret transgenic mice without macroscopical tumors. Cancer Res., 68: 9451-9458, 2008.
16. Bazhin, A.V., Dalke, C., Willner, N., Abschütz, O., Wildberger, H.G.H., Philippov, P.P., Dummer, R., Graw, J., de Angelis, M.H., Schadendorf, D., Umansky, V., and Eichmuller, S.B. Cancer-retina antigens as potential paraneoplastic antigens in melanoma-associated retinopathy. Int. J. Cancer, 124: 140-149, 2009.
17. Lakshmikanth, T., Burke, S., Hassan Ali, T., Kimpfler, S., Francesco, F., Ruggeri, L., Capanni, M., Umansky, V., Paschen, A., Sucker, A., Pende, D., Groh, V., Biassoni, R., Höglund, P., Kato, M., Shibuya, K., Schadendorf, D., Anichini, A., Ferrone, S., Velardi, A., Kärre, K., Shibuya, A., Carbone, E., Colucci, F. Receptor-mediated recognition of melanoma by natural killer cells and its implications for immunotherapy. J. Clin. Invest., 119: 1251-1263, 2009.
18. Zhao, F., Falk, C., Osen, W., Kato, M., Schadendorf, D., and Umansky, V. Activation of p38 MAPK Drives Dendritic Cells to Become Tolerogenic in Ret Transgenic Mice Spontaneously Developing Melanoma. Clin.Cancer Res., 15: 4382-4390, 2009.
19. Ramacher, M., Umansky, V., and Efferth, T. Effect of artesunate on immune cells in ret transgenic mouse melanoma model. Anti-Cancer Drugs, 2009, in press.
20. Kimpfler, S., Sevko, A., Ring, S., Falk, C., Osen, W., Frank, K., Kato, M., Mahnke, K., Schadendorf, D., and Umansky, V. Skin melanoma development in ret transgenic mice despite the depletion of CD25+FoxP3+ regulatory T cells in lymphoid organs. J. Immunol., 183: 6330-6337, 2009.
21. Bazhin, A.V., Kahnert, S., Kimpfler, S., Schadendorf, D., and Umansky, V. Distinct metabolism of cAMP in regulatory and helper CD4+ T cells. Mol. Immunol., 47: 678-674, 2010.
22. Umansky, V., and Guinn, B.A. ESCII-PIVAC meeting "Recent advances in cancer immunotherapy with an emphasis on cancer vaccines" held in Athens, 9-11 October 2008. Cancer Immunol. Immunother. 59: 635-640, 2010.
23. Umansky, V. Conference Scene: The 3rd International Cancer Vaccine Conference. Immunotherapy, 2: 151-154, 2010.
24. Schneider, T., Kimpfler, S., Warth, A., Schnabel, P.A., Dienemann, H., Schadendorf, D., Hoffmann, H., Umansky, V. Foxp3+ regulatory T cells and natural killer cells distinctly infiltrate primary tumors and draining lymph nodes in pulmonary adenocarcinoma. J. Thoracic Oncology, 2010, in press.
