Dr. Manuela Hummel

Dr. Manuela Hummel

Dr. Manuela Hummel




+49 6221 42 2135


+49 6221 42 2397


TP 4



Area of Work

I am part of the systems medicine CLIOMMICS project, which aims in personalizing the treatment for multiple myeloma patients. We develop and improve prognostic models for survival, response to treatment and side effects by integration of different “omics”, clinical, cytogenetic and imaging data.


  • Biostatistics department at the DKFZ from October 2013
  • Senior analyst technician at the Centre for Genomic Regulation (CRG), Barcelona, Spain, 2008-2013
  • PhD, Institute for Medical Informatics, Biometry and Epidemiology (IBE), University of Munich, 2009
  • Diploma in Statistics, University of Munich, 2005

Selected Publications

  1. Llorens F, Hummel M, Pantano L, Pastor X, Vivancos A, Castillo E, Matllin H, Ferrer A, Ingham M, Noguera M, Kofler R, Dohm CJ, Pluvinet R, Bayés M, Himmelbauer H, del Rio AJ, Martí E, Sumoy L. Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor. BMC Genomics 2013; 14:371.
  2. Hummel M, Bonnin S, Lowy E, Roma G. TEQC: an R-package for quality control in target capture experiments. Bioinformatics 2011; 27 (9): 1316-1317. doi: 10.1093/bioinformatics/btr122
  3. Hummel M, Metzeler KH, Buske C, Bohlander SK, Mansmann U. Association between a Prognostic Gene Signature and Functional Gene Sets. Bioinformatics and Biology Insights 2008; 2: 335-347.
  4. Metzeler KH, Hummel M, Bloomfield CD, Spiekermann K, Braess J, Sauerland M-C, Heinecke A, Radmacher M, Marcucci G, Whitman SP, Maharry K, Paschka P, Larson RA, Berdel WE, Büchner T, Wörmann B, Mansmann U, Hiddemann W, Bohlander SK, Buske C. An 86 probe set gene expression signature predicts survival in cytogenetically normal acute myeloid leukemia. Blood 2008; 112(10):4193-201. doi 10.1182/blood-2008-02-134411.
  5. Hummel M, Meister R, Mansmann U. GlobalANCOVA: Exploration and Assessment of Gene Group Effects. Bioinformatics 2008; 24 (1): 78-85.


R-package for plotting heatmaps with mixed-type data

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