Dr. Natalia Becker

Dr. Natalia Becker

Dr. Natalia Becker

Position:

Scientist

Phone:

+49 6221 42 2263

Fax:

+49 6221 42 2397

Building:

TP 4

Room:

S4.222

Area of Work

statistical computing, clinical trails,  machine learning, high-dimensional data,, statistical support for cancer-related research

Special Interest

classification, variable selection, penalisation, prediction and survival analysis, biomarker discovery

Selected Literature

  • Nakata S, Campos B, Bageritz J, Bermejo JL, Becker N, Engel F, Acker T, Momma S, Herold-Mende C, Lichter P, Radlwimmer B, Goidts V. LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells. Brain Pathol. 2013 Jan;23(1):60-72. doi: 10.1111/j.1750-3639.2012.00618.x.Epub 2012 Aug 30. PubMed PMID: 22805276. 
  • Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues  T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell. 2012 Oct 16;22(4):425-37. doi: 10.1016/j.ccr.2012.08.024. PubMed PMID: 23079654.  
  • Becker N, Toedt G, Lichter P, Benner A. Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data. BMC Bioinformatics. 2011 May 9;12:138. doi: 10.1186/1471-2105-12-138. PubMed PMID: 21554689; PubMed Central PMCID: PMC3113938. 
  • Becker N, Werft W, Toedt G, Lichter P, Benner A. penalizedSVM: a R-package for feature selection SVM classification. Bioinformatics. 2009 Jul 1;25(13):1711-2. doi: 10.1093/bioinformatics/btp286. Epub 2009 Apr 27. PubMed PMID: 19398451.
Pubmed


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