The Alliance examines how the latest results in immunodiagnosis and immunotherapy can be applied for the benefit of the patients in model diseases like leukemia, hepatocellular carcinoma and melanoma . The aim is closing the gap between basic research and the research of animal models on the one hand and application-oriented science on the other in order to develop urgently needed new therapies for highly relevant diseases. The repertory of diseases is based on the great experience of the members of the alliance with these tumour entities.
In addition, these tumor entities represent examples for different types of tumor diseases. Hepatocellular carcinomas are often associated with viral infection, offering viral antigens as ideal targets for immunotherapy. Leukemia cells are particularly well-suited for immunotherapy because of their accessibility and melanoma, finally, serves as a model for solid, virus independent tumors in the Alliance.

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