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Ausgewählte Publikationen Prof. Dr. Philipp Beckhove
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Beckhove P, Warta R, Lemke B, Stoycheva D, Momburg F, Schmitz-Winnenthal H, Ahmadi R, Dyckhoff G, Bucur M, Jünger S, Schoeler T, Lennerz V, Woelfel T, Unterberg A, Herold-Mende C 2010. Rapid T-cell based identification of tissue antigens by automated two-dimensional protein fractionation. J Clin Invest, 2010 Jun 1;120(6):2230-42, DOI 10.1172/JCI37646 (IF: 16,6)
Voss RH, Thomas S, Pfirschke C, Hauptrock B, Klobuch S, Kuball J, Grabowski M, Engel R, Guillaume P, Romero P, Huber C, Beckhove P, Theobald M. Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single chain TCR transduced human T cells. Blood. 2010 Apr 8. (Epub ahead of print) (IF: 9,7)
Blatner NR, Bonertz A, Beckhove P, Cheon EC, Krantz SB, Strouch M, Weitz J, Koch M, Halverson AL, Bentrem DJ, Khazaie K. In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6430-5. Epub 2010 Mar 22 (IF: 9,4)
Schmitz-Winnenthal, F. H. +, Pietsch, D.H., Schimmack, S. +, Bonertz, A., Udonta F., Ge, Y., Galindo, L. +, Volk, C. +, Zgraggen, K. +, Koch M., Buechler, M. +, Weitz, J. +, and Beckhove, P. Chronic pancreatitis is associated with disease-specific regulatory T cell responses. Gastroenterology. 2010 Mar;138(3):1178-88. (IF: 12,6)
Bonertz A., Weitz J. +, Pietsch D.H., Rahbari N.N., Schlude C., Ge Y., Jünger S., Vlodavsky I. +, Khazaie K., Jäger D., Reissfelder C., Antolovic D., Aigner M., Koch M. +, and Beckhove P. Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma. J Clin Invest 2009 (11): 3311-21 (IF: 16,6)
Bonertz A, Weitz J, Pietsch DH, Rahbari NN, Schlude C, Ge Y, Juenger S, Vlodavsky I, Khazaie K, Jaeger D, Reissfelder C, Antolovic D, Aigner M, Koch M, Beckhove P. Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma. J Clin Invest. 2009 Nov;119(11):3311-21. doi: 10.1172/JCI39608. Epub 2009 Oct 5.
N. Sommerfeldt*, P. Beckhove*, F. Schütz, C. Choi, Y. Ge, M. Bucur, C. Sohn, A. Schneeweis, J. Rom, D. Pollmann, D. Leucht , I. Vlodavsky and V. Schirrmacher. Heparanase: a new metastasis-associated antigen recognized in breast cancer patients by spontaneously induced memory T lymphocytes. Cancer Res., 66:7716-23, 2006*. These authors contributed equally to the study.
Choi C., Witzens M., Bucur M., Feuerer, M., Sommerfeldt N., Trojan, A, Ho A., Schirrmacher V., Goldschmidt H. and Beckhove P. :Enrichment of functional CD8 Memory T Cells specific for MUC1 in Bone Marrow of Multiple Myeloma Patients. Blood, 105:2132-4. 2005
Karcher J.*, Dyckhoff G.*, Beckhove P.*, Reisser C., Brysch M., Ziouta Y., Helmke B., Weidauer H., Schirrmacher V. and Herold-Mende C.: Anti-Tumor Vaccination of Patients with HNSCC with autologous Virus-modified Tumor Cells. Cancer Res., 64:8057-61, 2004. (*: These authors contributed equally to the study.)
Beckhove P., Feuerer M., Dolenc M., Choi C., Sommerfeldt N., Schwendemann J., Ehlert K., Altevogt P., Schuetz F., Bastert G., Schirrmacher V. and Umansky V.: Specifically activated CD45R0+ central and effector memory but not CD45RA+ naïve T cells from bone marrow of cancer patients selectively home to and reject xenotransplanted autologous tumors. J. Clin. Invest., 114:67-76, 2004.
Steiner H.H., Bonsanto M.M., Beckhove P., Brysch M., Schuele-Freyer R., Geletneky K., Kremer P., Ranaie G., Bauer H., Kunze S., Schirrmacher V. and Herold-Mende C.: Anti-tumor vaccination of patients with glioblastoma muliforme in a case-control study: Feasibility, safety and clinical benefit. J. Clin. Oncol., 22:4272-81, 2004.
Feuerer M.*, Beckhove P.*, Garbi N.*, Mahnke Y., Limmer A., Hommel M., Hämmerling G., Kyewski B., Hamann A., Umansky V., Schirrmacher V.: Bone marrow as a priming site for T cell responses to blood borne antigen. Nature Medicine, 9:1151-57, 2003. (*: Feuerer M, Beckhove, P and Garbi, N contributed equally to this study.)
Feuerer M.*, Beckhove P.*, Bai L., Solomayer E.F., Bastert G., Diel I.J., Pedain C., Oberniedermayr M., Schirrmacher V. and Umansky V.; Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow. Nature Medicine, 7:452-8, 2001. (*P.B. and M.F. contributed equally to the study.)
