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Ausgewaehlte Publikationen

Gupta, N., Grebhardt, S., Mayer, D. (2012) Janus kinase 2 - a novel negative regulator of estrogen receptor α function. Cell. Signal. 24(1), 151-161.

Aleem, E., Nehrbass, D., Klimek, F., Mayer, D., Bannasch, P. (2011) Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis.Toxicol. Pathol. 39(3), 524-543.

Gupta, N., Schmitt, F., Grebhardt, S., Mayer, D. (2011) Beta-catenin is a positive regulator of estrogen receptor-α function in breast cancer cells. Cancers 3(3), 2990-3001.

Yu, L., Wang, C.Y., Shi, J., Miao, L., Du, X., Mayer, D., Zhang, J. (2011) Estrogen promotes invasion of prostate cancer cells in a paracrine manner through upregulation of matrix metalloproteinase 2 in prostatic stromal cells. Endocrinology 152(3), 773-781.

De Souza Rocha Simonini, P., Breiling, A., Gupta, N., Youns, M., Malekpour, M., Volinia, S., Najmabadi, H., Diederichs, S., Mayer, D., Lyko, F., Hoheisel, J.D., Riazalhosseini, Y. (2010) Epigenetically de-regulated microRNA-375 activates estrogen receptor-alpha signaling in breast cancer. Cancer Res. 70(22), 9175-9184.

Medunjanin, S., Weinert, S., Schmeisser, A., Mayer, D., Braun-Dullaeus, R. (2010) Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-alpha. Mol. Biol. Cell 21(9), 1620-1628.

Grisouard, J., Mayer, D. (2009) Specific involvement of glycogen synthase kinase-3 in the function and activity of steroid hormone receptors reveals the complexity of their regulation. Review. J. Steroid Biochem. Mol. Biol. 117, 87-92.

Shukla, A., Grisouard, J., Ehemann, V., Hermani, A., Enzmann, H., Mayer, D. (2009) Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines. Endocr. Relat. Cancer 16(2), 429-441.

Mayer, D., Shukla, A. Enzmann, H. (2008) Proliferative effects of insulin analogues on mammary epithelial cells. Arch. Physiol. Biochem. 114, 38-44.

Mukherjee, B., Mayer, D. (2008) Dihydrotestosterone interacts with EGFR / MAPK signalling and modulates EGFR levels in androgen receptor-positive LNCaP prostate cancer cells. Int. J. Oncol. 33, 623-629.

Grisouard, J., Medunjanin, S., Hermani, A., Shukla, A., Mayer, D. (2007) Glycogen synthase kinase-3 protects estrogen receptor-alpha from proteasomal degradation and is required for full transcriptional activity of the receptor. Mol. Endocrinol. 21, 2427-2439.

Hermani, A., De Servi, B., Medunjanin, S., Tessier, P.A., Mayer, D. (2006) S100A8 and S100A9 activate MAP kinase and NF-kappaB signalling pathways and trigger translocation of RAGE in human prostate cancer cells. Exp. Cell Res. 312, 184-197.

Hermani, A., Hess, J., De Servi, B., Medunjanin, S., Grobholz, R., Trojan, L., Angel, P., Mayer, D. (2005) The calcium-binding proteins S100A8 and S100A9 are novel diagnostic markers that are co-expressed with the receptor for advanced glycation end products (RAGE) in human prostate cancer. Clin. Cancer Res. 11, 5146-5152.

De Servi, B., Hermani, A., Medunjanin, S., Mayer, D. (2005) Impact of PKC-delta on estrogen receptor localisation and activity in breast cancer cells. Oncogene 24, 4946-4955.

Medunjanin, S., Hermani, A., De Servi, B., Grisouard, J., Rincke, G., Mayer, D. (2005) Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor-alpha and is involved in the regulation of receptor activity. J. Biol. Chem. 280, 33006-33014.

Liao, Y., Abel, U., Grobholz, R., Hermani, A., Trojan, L., Angel, P., Mayer, D. (2005) Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumour grade. Human Pathol. 36, 1186-1196.

Mayer, D., Forstner, K. (2004) Impact of dehydroepiandrosterone on hepatocarcinogenesis in the rat (Review). Int. J. Oncol. 25, 1021-1030.

Liao, Y., Grobholz, R., Abel, U., Trojan, L., Michel, M.S., Angel, P., Mayer, D. (2003) Increase of AKT/PKB expression correlates with Gleason pattern in human prostate cancer. Int. J. Cancer (Cancer Cell Biology) 107, 676-680.

Schnarr, B., Strunz, K., Ohsam, J., Benner, A., Wacker, J., Mayer, D. (2000) Downregulation of insulin-like growth factor-1 receptor and insulin receptor substrate-1 in advanced human breast cancer. Int. J. Cancer (Pred. Oncol.) 89, 506-513.

Letzte Aktualisierung: 20.12.2011 Seitenanfang